CN106177409A - A kind of Chinese medicine composition for the treatment of radiation dermatitis - Google Patents

A kind of Chinese medicine composition for the treatment of radiation dermatitis Download PDF

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CN106177409A
CN106177409A CN201610593571.XA CN201610593571A CN106177409A CN 106177409 A CN106177409 A CN 106177409A CN 201610593571 A CN201610593571 A CN 201610593571A CN 106177409 A CN106177409 A CN 106177409A
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herba
radix
rhizoma
chinese medicine
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林红丽
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Abstract

nullThe invention discloses the Chinese medicine composition of a kind for the treatment of radiation dermatitis，Its raw material of Chinese medicine and weight be: Alectoria asiatica Du Rietz 10 20 parts，Radix achyranthis asperae (Herba Achyranthis Asperae) 10 20 parts，Radix Scrophulariae 5 15 parts，Rhizoma Saururi (Herba Saururi) 10 20 parts，Herba abutili indici 10 20 parts，Radix Rehmanniae 10 20 parts，Rhizoma Coptidis 5 15 parts，Herba Portulacae 10 20 parts，Herba Artemisiae Scopariae 10 20 parts，Folium Eucalypti Robustae 5 15 parts，Radix Ophiopogonis 10 20 parts，Herba Agrimoniae 10 20 parts，Flos Chrysanthemi 10 20 parts，Indigo Naturalis 5 15 parts，Herba Plantaginis 10 20 parts，Radix Gymnematis Sylvestris 10 20 parts，Stone trailing plants 5 15 parts，Caulis et Folium cayratiae trifoliae 10 20 parts，Rhizoma Polygoni Cuspidati 10 20 parts，Cortex Lycii 10 20 parts，Olibanum 5 15 parts，Radix Et Rhizoma Rhei 10 20 parts，Rhizoma Polygoni Cuspidati 10 20 parts，5 15 parts of Radix Glycyrrhizae.It has clearing away heat and cooling blood, subduing swelling and detoxicating, inrigorating qi and promoting blood circulation, effect of dissipating blood stasis dredging collateral, and treating radiation dermatitis is evident in efficacy, safe and reliable.

Description

A kind of Chinese medicine composition for the treatment of radiation dermatitis
Technical field
The present invention relates to the medicinal preparation not determining structure of a kind of traditional herbal medicines, especially a kind of therapeutic radiation skin Scorching Chinese medicine composition.
Background technology
Radiodermatitis is that the skin mucosa caused due to lonizing radiation (mainly β and gamma-rays and x-ray) irradiation is struvite Infringement.Primary disease is mainly seen in the radiocurable patient of acceptance and is engaged in radiation work and protects not tight person.Lonizing radiation irradiate and can draw Play a series of dermoreactions and damage, show as reversible alopecia, dermatitis, pigmentation and irreversible skin and wither Contracting, sebaceous gland, the destruction of sweat gland and permanent hair disappearance, so that radium necrosis, followed by form ulcer.At present, clinical It is soft that upper treating radiation dermatitis many employings affected area smears Calamine Lotion, vitamin E or recombinant human epidermal growth factor class Cream, also can take the Therapeutic Method such as excision to severe patient.Its uncertain therapeutic efficacy is cut, and costly, and clinical application is by one Fixed restriction.
The traditional Chinese medical science is thought, radiodermatitis, belongs to the traditional Chinese medical science and " burns " category.Lonizing radiation are " burning hot poison are evil ", are by YIN damaged by pathogenic heat, Cause heat accumulate flesh natural fibre line of meat desquamation, pruritus, ulcer, heat in blood produce erythema, blood stasis cause pigmentation, coagulation of QI-blood, meridians block and cause Causalgia.Therefore the treatment of radiation skin injury should use heat and toxic materials clearing away medicine, tonic and drug for invigorating blood circulation and eliminating stasis with protection.
According to theory of Chinese medical science, for the pathogeny of radiodermatitis, with heat-clearing and toxic substances removing, inrigorating qi and promoting blood circulation as the rule for the treatment of, carry out Dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Prior art use hormones, vitamins or recombinant human epidermal growth factor class Drug therapy put to overcome Penetrating property dermatitis exist uncertain therapeutic efficacy cut, costly, the deficiency of medication inconvenience, the present invention provide a kind of preparation convenient, evident in efficacy, The Chinese medicine composition of safe and reliable treating radiation dermatitis.
The technical solution adopted for the present invention to solve the technical problems is: the Chinese medicine composition of a kind for the treatment of radiation dermatitis Thing, it is characterised in that: its raw material of Chinese medicine and weight be: Alectoria asiatica Du Rietz 10-20 part, Radix achyranthis asperae (Herba Achyranthis Asperae) 10-20 part, Radix Scrophulariae 5-15 Part, Rhizoma Saururi (Herba Saururi) 10-20 part, Herba abutili indici 10-20 part, Radix Rehmanniae 10-20 part, Rhizoma Coptidis 5-15 part, Herba Portulacae 10-20 part, Herba Artemisiae Scopariae 10- 20 parts, Folium Eucalypti Robustae 5-15 part, Radix Ophiopogonis 10-20 part, Herba Agrimoniae 10-20 part, Flos Chrysanthemi 10-20 part, Indigo Naturalis 5-15 part, Herba Plantaginis 10-20 part, Radix Gymnematis Sylvestris 10-20 part, stone trailing plants 5-15 part, Caulis et Folium cayratiae trifoliae 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Cortex Lycii 10-20 Part, Olibanum 5-15 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: the Chinese medicine composition of a kind for the treatment of radiation dermatitis, it is characterised in that: wherein Medicine raw material and weight be: Alectoria asiatica Du Rietz 15 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 15 parts, Radix Scrophulariae 10 parts, Rhizoma Saururi (Herba Saururi) 15 parts, Herba abutili indici 15 parts, raw Radix Rehmanniae 15 parts, Rhizoma Coptidis 10 parts, Herba Portulacae 15 parts, Herba Artemisiae Scopariae 15 parts, Folium Eucalypti Robustae 10 parts, Radix Ophiopogonis 15 parts, Herba Agrimoniae 15 parts, Flos Chrysanthemi 15 Part, Indigo Naturalis 10 parts, Herba Plantaginis 15 parts, Radix Gymnematis Sylvestris 15 parts, stone trailing plants 10 parts, Caulis et Folium cayratiae trifoliae 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Cortex Lycii 15 Part, Olibanum 10 parts, Radix Et Rhizoma Rhei 15 parts, Rhizoma Polygoni Cuspidati 15 parts, 10 parts of Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.The present invention In Chinese medicine composition: Alectoria asiatica Du Rietz has nourishing the liver and kidney, effect of convergence hidroschesis；Radix achyranthis asperae (Herba Achyranthis Asperae) has blood circulation promoting and blood stasis dispelling, inducing diuresis for treating stranguria syndrome, clear Effect of pyrolysis table；Radix Scrophulariae has effect of removing heat from blood YIN nourishing, eliminating fire and detoxication；Rhizoma Saururi (Herba Saururi) has eliminating damp-heat, detumescence, the merit of removing toxic substances Effect；Herba abutili indici has effect of wind and heat dispersing, preventing phlegm from forming and stopping coughing, subduing swelling and detoxicating；Radix Rehmanniae has clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, stops Effect of regulating menstruation bitterly；Rhizoma Coptidis has effect of heat clearing and damp drying, eliminating fire and detoxication；Herba Portulacae has heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, dehumidifying Treating stranguria effect；Herba Artemisiae Scopariae has clearing away heat-damp and promoting diuresis, effect of jaundice eliminating subcutaneous ulcer；Folium Eucalypti Robustae has effect of heat-clearing and toxic substances removing；Radix Ophiopogonis has Effect that YIN nourishing and the production of body fluid promoting, lung moistening clear away heart-fire；Herba Agrimoniae has astringing to arrest bleeding, stomach invigorating preventing the attack (or recurrence) of malaria, effect of detoxification sore treatment；Flos Chrysanthemi has thin Wind heat clearing away, effect of subduing swelling and detoxicating；Indigo Naturalis has effect of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire；Herba Plantaginis has heat clearing away Diuresis, effect of removing pathogenic heat from blood and toxic substance from the body；Radix Gymnematis Sylvestris has clearing away heat and cooling blood, evacuation of pus detumescence, effect of pain relieving granulation promoting；Stone trailing plants has heat clearing away Effect of removing toxic substances；Caulis et Folium cayratiae trifoliae has clearing away heat-damp and promoting diuresis, effect of removing toxic substances and promoting subsidence of swelling；Rhizoma Polygoni Cuspidati has promoting blood circulation to remove blood stasis, dispelling wind and removing obstruction in the collateral, clear Diarrhea of heat type is wet, removing toxic substances, effect of relieving cough and resolving phlegm；Cortex Lycii has removing heat from blood except steaming, effect of lung heat clearing pathogenic fire reducing；Olibanum has row of invigorating blood circulation Gas, pain relieving, effect of detumescence and promoting granulation；Radix Et Rhizoma Rhei has pathogenic fire purging removing food stagnancy, heat-clearing and toxic substances removing, cooling blood for hemostasis, effect of blood stasis dispelling cough-relieving；Rhizoma Polygoni Cuspidati There is effect of promoting blood circulation to remove blood stasis, dispelling wind and removing obstruction in the collateral, clearing away heat-damp and promoting diuresis, removing toxic substances, relieving cough and resolving phlegm；Radix Glycyrrhizae have invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, Expelling phlegm for arresting cough, effect of coordinating the actions of various ingredients in a prescription.Drug component in the present composition, through dialectical compatibility, complements each other using, There is synergism, play clearing away heat and cooling blood, subduing swelling and detoxicating, inrigorating qi and promoting blood circulation, effect of dissipating blood stasis dredging collateral altogether, radiodermatitis is reached mark This double purpose controlled.
The component of the present composition all uses natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, low cost.It is abided by Following the prescriptions principle of the traditional Chinese medical science, various component drug use the use that is decocted in water for oral dose.Checking and middle adverse drug reaction by clinic application (ADR) safety evaluatio, it is evident in efficacy, safe and reliable, mild in medicine property and, toxic and side effects do not occurs, total effective rate 84%, cure Rate reaches 69%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
The Chinese medicine composition of a kind for the treatment of radiation dermatitis, its raw material of Chinese medicine and weight proportion be: Alectoria asiatica Du Rietz 15g, Radix achyranthis asperae (Herba Achyranthis Asperae) 15g, Radix Scrophulariae 10g, Rhizoma Saururi (Herba Saururi) 15g, Herba abutili indici 15g, Radix Rehmanniae 15g, Rhizoma Coptidis 10g, Herba Portulacae 15g, Herba Artemisiae Scopariae 15g, Folium Eucalypti Robustae 10g, Radix Ophiopogonis 15g, Herba Agrimoniae 15g, Flos Chrysanthemi 15g, Indigo Naturalis 10g, Herba Plantaginis 15g, Radix Gymnematis Sylvestris 15g, stone trailing plants 10g, SANYE crow liana Certain kind of berries 15g, Rhizoma Polygoni Cuspidati 15g, Cortex Lycii 15g, Olibanum 10g, Radix Et Rhizoma Rhei 15g, Rhizoma Polygoni Cuspidati 15g, Radix Glycyrrhizae 10g.
Embodiment 2
The Chinese medicine composition of a kind for the treatment of radiation dermatitis, its raw material of Chinese medicine and weight proportion be: Alectoria asiatica Du Rietz 10g, Radix achyranthis asperae (Herba Achyranthis Asperae) 20g, Radix Scrophulariae 5g, Rhizoma Saururi (Herba Saururi) 20g, Herba abutili indici 10g, Radix Rehmanniae 20g, Rhizoma Coptidis 5g, Herba Portulacae 20g, Herba Artemisiae Scopariae 10g, Folium Eucalypti Robustae 15g, Radix Ophiopogonis 10g, Herba Agrimoniae 20g, Flos Chrysanthemi 10g, Indigo Naturalis 15g, Herba Plantaginis 10g, Radix Gymnematis Sylvestris 20g, stone trailing plants 5g, Caulis et Folium cayratiae trifoliae 20g, Rhizoma Polygoni Cuspidati 10g, Cortex Lycii 20g, Olibanum 5g, Radix Et Rhizoma Rhei 20g, Rhizoma Polygoni Cuspidati 10g, Radix Glycyrrhizae 15g.
Embodiment 3
The Chinese medicine composition of a kind for the treatment of radiation dermatitis, its raw material of Chinese medicine and weight proportion be: Alectoria asiatica Du Rietz 20g, Radix achyranthis asperae (Herba Achyranthis Asperae) 10g, Radix Scrophulariae 15g, Rhizoma Saururi (Herba Saururi) 10g, Herba abutili indici 20g, Radix Rehmanniae 10g, Rhizoma Coptidis 15g, Herba Portulacae 10g, Herba Artemisiae Scopariae 20g, Folium Eucalypti Robustae 5g, Radix Ophiopogonis 20g, Herba Agrimoniae 10g, Flos Chrysanthemi 20g, Indigo Naturalis 5g, Herba Plantaginis 20g, Radix Gymnematis Sylvestris 10g, stone trailing plants 15g, Caulis et Folium cayratiae trifoliae 10g, Rhizoma Polygoni Cuspidati 20g, Cortex Lycii 10g, Olibanum 15g, Radix Et Rhizoma Rhei 10g, Rhizoma Polygoni Cuspidati 20g, Radix Glycyrrhizae 5g.
Embodiment 4
The Chinese medicine composition of a kind for the treatment of radiation dermatitis, its raw material of Chinese medicine and weight proportion be: Alectoria asiatica Du Rietz 12g, Radix achyranthis asperae (Herba Achyranthis Asperae) 18g, Radix Scrophulariae 8g, Rhizoma Saururi (Herba Saururi) 18g, Herba abutili indici 12g, Radix Rehmanniae 18g, Rhizoma Coptidis 8g, Herba Portulacae 18g, Herba Artemisiae Scopariae 12g, Folium Eucalypti Robustae 13g, Radix Ophiopogonis 12g, Herba Agrimoniae 18g, Flos Chrysanthemi 12g, Indigo Naturalis 13g, Herba Plantaginis 12g, Radix Gymnematis Sylvestris 18g, stone trailing plants 8g, Caulis et Folium cayratiae trifoliae 18g, Rhizoma Polygoni Cuspidati 12g, Cortex Lycii 18g, Olibanum 8g, Radix Et Rhizoma Rhei 18g, Rhizoma Polygoni Cuspidati 12g, Radix Glycyrrhizae 13g.
Embodiment 5
The Chinese medicine composition of a kind for the treatment of radiation dermatitis, its raw material of Chinese medicine and weight proportion be: Alectoria asiatica Du Rietz 18g, Radix achyranthis asperae (Herba Achyranthis Asperae) 12g, Radix Scrophulariae 13g, Rhizoma Saururi (Herba Saururi) 12g, Herba abutili indici 18g, Radix Rehmanniae 12g, Rhizoma Coptidis 13g, Herba Portulacae 12g, Herba Artemisiae Scopariae 18g, Folium Eucalypti Robustae 8g, Radix Ophiopogonis 18g, Herba Agrimoniae 12g, Flos Chrysanthemi 18g, Indigo Naturalis 8g, Herba Plantaginis 18g, Radix Gymnematis Sylvestris 12g, stone trailing plants 13g, Caulis et Folium cayratiae trifoliae 12g, Rhizoma Polygoni Cuspidati 18g, Cortex Lycii 12g, Olibanum 13g, Radix Et Rhizoma Rhei 12g, Rhizoma Polygoni Cuspidati 18g, Radix Glycyrrhizae 8g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: by prescription Raw material of Chinese medicine put in container, add cold water and cover powder, soak 15～20 minutes, added water no powder about 8 centimetres, and carried out Decoct for the first time, at a simmer before use intense fire to decoct, with slow fire boiling 20～30 minutes after boiling；Second time decocts, and added water no medicine About 6 centimetres of face, decocts 15～20 minutes after water boiling.Twice decoction is removed slag extracting juice, merges.
The present invention, with the Chinese medicine composition of a kind for the treatment of radiation dermatitis given by embodiment 1, does clinical efficacy and sums up As follows:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 46 example, the maleest 27 examples, female 19 example, year Age 12～60 years old.
Two, diagnostic criteria:
1, having radioactivity contact history according to patient, infringement betides radiation position and the clinical characters similar to thermal burn is examined Disconnected；
2, carry out pathologic finding, help diagnosis.
Three, usage and dosage: during clinical practice, one day potion, decocting twice extracting juice about 300ml, take for twice in point morning, evening, Six days courses for the treatment of.
Four, criterion of therapeutical effect:
1, cure: illing skin heals, red and swollen elimination, check normal；
2, take a turn for the better: skin damage area reduces, and redness substantially alleviates；
3, do not heal: sings and symptoms is without significant change.
Five, therapeutic effect: in this clinical observation case, take medicine 3-10 the course for the treatment of, cure 32 examples, take a turn for the better 7 examples, the most 7 examples. During treatment, centering clinical drug causes all types of anaphylaxis, causes each system of human body, organ, the merit of tissue suspected of medicine Can and form in terms of abnormal, cause the mutagenesis reactions such as cancer, the dependency of medicine suspected of medicine and think important or have Other untoward reaction being worth are evaluated, and i.e. middle adverse drug reaction (ADR) is evaluated, and do not occur untoward reaction and poison pair to make With.
Six, model case:
Case 1: Xiao, man, 26 years old.CT Room practice doctor, there is redness in two thigh fronts, have causalgia sense, accompany scratchiness, touch it Severe pain.After 2 courses for the treatment of of medicament taking prepared by the Chinese medicine composition of the present invention, affected part is red and swollen and pain of itching substantially alleviates, skin lesion Place's skin color major part recovers normal；Continue to take 2 courses for the treatment of, each transference cure, cure.
Case 2: Zhang, female, 26 years old, rear flank in X-ray examination ankle, ankle inside skin occurred intensive mottled red Swollen, companion's pruritus and calcination pain, once used Calamine Lotion, but it was warm or after sun direct projection, can recur, and even produced because of scratching Rotten to the corn and indolence.Take 1 course for the treatment of of medicament prepared by the Chinese medicine composition of the present invention, pain relief at erosion, rotten to the corn face Long-pending reduction, burning sensation alleviates；Continue after taking 2 courses for the treatment of, skin healing, incrustation；Consolidating after taking 1 course for the treatment of, incrustation comes off, red and swollen Disappearing, only remaining cicatrix, the colour of skin is increasingly normal, cures.

Claims (2)

1. the Chinese medicine composition of a treating radiation dermatitis, it is characterised in that: its raw material of Chinese medicine and weight be: hair Seven 10-20 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 10-20 part, Radix Scrophulariae 5-15 part, Rhizoma Saururi (Herba Saururi) 10-20 part, Herba abutili indici 10-20 part, Radix Rehmanniae 10-20 part, Rhizoma Coptidis 5-15 part, Herba Portulacae 10-20 part, Herba Artemisiae Scopariae 10-20 part, Folium Eucalypti Robustae 5-15 part, Radix Ophiopogonis 10-20 part, Herba Agrimoniae 10-20 Part, Flos Chrysanthemi 10-20 part, Indigo Naturalis 5-15 part, Herba Plantaginis 10-20 part, Radix Gymnematis Sylvestris 10-20 part, stone trailing plants 5-15 part, Caulis et Folium cayratiae trifoliae 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Cortex Lycii 10-20 part, Olibanum 5-15 part, Radix Et Rhizoma Rhei 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Radix Glycyrrhizae 5-15 Part.
The Chinese medicine composition of a kind for the treatment of radiation dermatitis the most according to claim 1, it is characterised in that: its raw material of Chinese medicine And weight is: Alectoria asiatica Du Rietz 15 parts, Radix achyranthis asperae (Herba Achyranthis Asperae) 15 parts, Radix Scrophulariae 10 parts, Rhizoma Saururi (Herba Saururi) 15 parts, Herba abutili indici 15 parts, Radix Rehmanniae 15 Part, Rhizoma Coptidis 10 parts, Herba Portulacae 15 parts, Herba Artemisiae Scopariae 15 parts, Folium Eucalypti Robustae 10 parts, Radix Ophiopogonis 15 parts, Herba Agrimoniae 15 parts, Flos Chrysanthemi 15 parts, blue or green Black pigment used by women in ancient times to paint their eyebrows 10 parts, Herba Plantaginis 15 parts, Radix Gymnematis Sylvestris 15 parts, stone trailing plants 10 parts, Caulis et Folium cayratiae trifoliae 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Cortex Lycii 15 parts, breast Fragrant 10 parts, Radix Et Rhizoma Rhei 15 parts, Rhizoma Polygoni Cuspidati 15 parts, 10 parts of Radix Glycyrrhizae.
CN201610593571.XA 2016-07-26 2016-07-26 A kind of Chinese medicine composition for the treatment of radiation dermatitis Pending CN106177409A (en)

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