CN103735991A - Traditional Chinese medicine composition for treating purpura - Google Patents

Traditional Chinese medicine composition for treating purpura Download PDF

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CN103735991A
CN103735991A CN201410011769.3A CN201410011769A CN103735991A CN 103735991 A CN103735991 A CN 103735991A CN 201410011769 A CN201410011769 A CN 201410011769A CN 103735991 A CN103735991 A CN 103735991A
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parts
radix
fructus
chinese medicine
medicine composition
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姜丽莎
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Abstract

The invention relates to a traditional Chinese medicine composition for treating purpura. The traditional Chinese medicine composition comprises the following raw traditional Chinese medicines in parts by weight: 10 to 40 parts of radix rehmanniae, 5 to 20 parts of lithospermum, 5 to 25 parts of couch grass root, 5 to 25 parts of isatis root, 5 to 20 parts of sanguisorba officinalis, 5 to 25 parts of radix paeoniae alba, 5 to 20 parts of angelica sinensis, 5 to 25 parts of glossy privet fruit, 5 to 25 parts of eclipta alba, 5 to 20 parts of honeysuckle, 5 to 20 parts of fructus forsythia, 5 to 25 parts of rhizoma atractylodis macrocephalae, 5 to 25 parts of rehmannia glutinosa, 5 to 20 parts of radix scrophulariae, 5 to 25 parts of poria, 5 to 20 parts of lycium barbarum, 5 to 25 parts of rhizoma alismatis, 5 to 20 parts of dogwood, 5 to 20 parts of fructus amomi, 5 to 20 parts of pangolin, and 5 to 15 parts of liquorice. The traditional Chinese medicine composition has the effects of tonifying kidney and enriching Yin, promoting circulation and removing stasis, purging fire for removing toxin, clearing away heat and drying dampness, and cooling blood for hemostasis, shows a remarkable effect on treating purpura, and has a reliable effect.

Description

A kind of Chinese medicine composition for the treatment of purpura
Technical field
The present invention relates to a kind of pharmaceutical product of not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of purpura ].
Background technology
Purpura is the general name of color change after skin and mucosal bleeding.Clinical manifestation is petechia, purpura and ecchymosis, does not generally exceed surface, while only having anaphylactoid purpura, can slightly swell, and starts as aubergine, presses and does not fade, and shoals gradually later, to left and right flavescence in two weeks, disappears.Onset is more anxious, and purpura easily occurs repeatedly, can betide skin, the mucosa at the each position of whole body.Erythra is various, and little person is as needle point sample, and large person becomes ecchymosis or hematoma, also can merge in flakes.During Acute onset, often with epistaxis, bleeding from the gum, have blood in stool, the symptom such as hematuria or vomiting, stomachache, arthralgia.Because primary disease is hematostaxis, without obvious inducement, and without obvious simultaneous phenomenon, therefore bring certain difficulty to treatment.At present, to purpura, adopt Chinese patent medicine to treat as Cornu rhinocerotis Dihuang Wan, ZHONGJIEFENG PIAN, tablet of cow-bezoar for tranquilization, Folium Nelumbinis ball etc. clinically, exist the poor deficiency of therapeutic effect.
The traditional Chinese medical science thinks, the cause of disease of purpura have deficiency and excess point.Outer because the heresy of affection due to external wind and heat, the damp and hot poison of holding under the arm accumulates and hinders in flesh table blood system, the absurd row of forcing blood, excessive skin pores key, take excess syndrome as main.In because plain body-centered temper insufficiency of blood, damage of kidney-YIN, hyperactivity of deficient fire, due to escape of blood from meridian, take deficiency syndrome as main.
According to theory of Chinese medical science, for the pathogeny of purpura, excess syndrome is take clearing away heat and cooling blood as Therapeutic Principle, and deficiency syndrome, take nourishing qi to stop, nourishing YIN to lower pathogenic fire as Therapeutic Principle, are carried out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome the deficiency for the treatment of purpura in prior art and exist weak curative effect, the invention provides a kind of prepare easy, cost is low, the Chinese medicine composition of evident in efficacy, the treatment purpura that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of purpura, it is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Rehmanniae 10-40 part, Radix Arnebiae (Radix Lithospermi) 5-20 part, Rhizoma Imperatae 5-25 part, Radix Isatidis 5-25 part, Radix Sanguisorbae 5-20 part, Radix Paeoniae Alba 5-25 part, Radix Angelicae Sinensis 5-20 part, Fructus Ligustri Lucidi 5-25 part, Herba Ecliptae 5-25 part, Flos Lonicerae 5-20 part, Fructus Forsythiae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-25 part, Radix Rehmanniae Preparata 5-25 part, Radix Scrophulariae 5-20 part, Poria 5-25 part, Fructus Lycii 5-20 part, Rhizoma Alismatis 5-25 part, Fructus Corni 5-20 part, Fructus Amomi 5-20 part, Squama Manis 5-20 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of purpura, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 25 parts, the Radix Rehmanniae, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Rhizoma Imperataes, 15 parts of Radix Isatidis, 10 parts of Radix Sanguisorbaes, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Angelicae Sinensis, 15 parts of Fructus Ligustri Lucidi, 15 parts of Herba Ecliptaes, 10 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts, Radix Rehmanniae Preparata, 10 parts of Radix Scrophulariaes, 15 parts of Poria, 10 parts of Fructus Lyciis, 15 parts of Rhizoma Alismatis, 10 parts of Fructus Corni, 10 parts of Fructus Amomis, 10 parts of Squama Maniss, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience guidance, selected medicament composing prescription.In Chinese medicine composition of the present invention: the Radix Rehmanniae has the effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, pain relieving regulating menstruation; Radix Arnebiae (Radix Lithospermi) has the effect of clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, removing toxic substances rash; Rhizoma Imperatae has the effect of cooling blood for hemostasis, heat-clearing and toxic substances removing; Radix Isatidis has the effect of heat-clearing and toxic substances removing, removing heat from blood detumescence, sore-throat relieving; Radix Sanguisorbae has the effect of cooling blood for hemostasis, removing toxic substances sore; The Radix Paeoniae Alba has the effect of clear and coherent blood vessels, nourishing blood to suppress the hyperactive liver, slow middle arresting sweating; Radix Angelicae Sinensis have enrich blood invigorate blood circulation, menstruction regulating and pain relieving, the effect of loosening bowel to relieve constipation; Fructus Ligustri Lucidi has the effect that nourishing the liver and kidney, tonifying YIN nourish blood; Herba Ecliptae has the effect of liver-nourishing kidney-boosting, cooling blood for hemostasis; Flos Lonicerae has the effect of heat-clearing and toxic substances removing, wind-heat dissipating; Fructus Forsythiae has the effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating; The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, the antiabortive effect of hidroschesis; Radix Rehmanniae Preparata has the effect of the yin nourishing of enriching blood, life essence-filling, marrow-benefitting; Radix Scrophulariae has the effect of removing heat from blood YIN nourishing, eliminating fire and detoxication; Poria has benefiting vital QI for tranquillizing, invigorating the spleen and regulating the stomach, dispels effect damp and hot, row water stopping leak; Fructus Lycii has the effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, strengthening the body resistance, spermatogenesis benefit marrow, enriching yin and nourishing kidney, benefiting vital QI for tranquillizing; Rhizoma Alismatis has promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil; Fructus Corni has the effect of liver and kidney tonifying, essence astringing and desertion stemming; Fructus Amomi has removing dampness appetizing, warming spleen and stopping diarrha, the antiabortive effect of regulating the flow of vital energy; Squama Manis has the effect of promoting blood circulation to remove obstruction in the collateral, detumescence and apocenosis, wind-expelling pain-stopping, lactogenesis; Radix Glycyrrhizae has the effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component is through dialectical compatibility, helps using mutual assistant, plays altogether the effect of tonifying kidney and nourishing yin, blood circulation promoting and blood stasis dispelling, eliminating fire and detoxication, heat clearing and damp drying, cooling blood for hemostasis, and the treatment of purpura is reached to treating both the principal and secondary aspects of a disease.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy reliable, and the property of medicine is gentle, does not occur toxic and side effects, and effective percentage reaches 90%, cure rate 65%.
The specific embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for purpura, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 25g, Radix Arnebiae (Radix Lithospermi) 10g, Rhizoma Imperatae 15g, Radix Isatidis 15g, Radix Sanguisorbae 10g, Radix Paeoniae Alba 15g, Radix Angelicae Sinensis 10g, Fructus Ligustri Lucidi 15g, Herba Ecliptae 15g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Rhizoma Atractylodis Macrocephalae 15g, Radix Rehmanniae Preparata 15g, Radix Scrophulariae 10g, Poria 15g, Fructus Lycii 10g, Rhizoma Alismatis 15g, Fructus Corni 10g, Fructus Amomi 10g, Squama Manis 10g, Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for purpura, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 10g, Radix Arnebiae (Radix Lithospermi) 20g, Rhizoma Imperatae 5g, Radix Isatidis 25g, Radix Sanguisorbae 12g, Radix Paeoniae Alba 10g, Radix Angelicae Sinensis 5g, Fructus Ligustri Lucidi 25g, Herba Ecliptae 10g, Flos Lonicerae 20g, Fructus Forsythiae 5g, Rhizoma Atractylodis Macrocephalae 25g, Radix Rehmanniae Preparata 10g, Radix Scrophulariae 20g, Poria 5g, Fructus Lycii 20g, Rhizoma Alismatis 10g, Fructus Corni 20g, Fructus Amomi 5g, Squama Manis 20g, Radix Glycyrrhizae 12g.
Embodiment 3
Treat a Chinese medicine composition for purpura, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 20g, Radix Arnebiae (Radix Lithospermi) 12g, Rhizoma Imperatae 10g, Radix Isatidis 20g, Radix Sanguisorbae 5g, Radix Paeoniae Alba 6g, Radix Angelicae Sinensis 12g, Fructus Ligustri Lucidi 5g, Herba Ecliptae 20g, Flos Lonicerae 12g, Fructus Forsythiae 15g, Rhizoma Atractylodis Macrocephalae 20g, Radix Rehmanniae Preparata 5g, Radix Scrophulariae 15g, Poria 10g, Fructus Lycii 12g, Rhizoma Alismatis 5g, Fructus Corni 15g, Fructus Amomi 12g, Squama Manis 5g, Radix Glycyrrhizae 6g.
Embodiment 4
Treat a Chinese medicine composition for purpura, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 30g, Radix Arnebiae (Radix Lithospermi) 15g, Rhizoma Imperatae 20g, Radix Isatidis 5g, Radix Sanguisorbae 15g, Radix Paeoniae Alba 12g, Radix Angelicae Sinensis 15g, Fructus Ligustri Lucidi 20g, Herba Ecliptae 5g, Flos Lonicerae 15g, Fructus Forsythiae 12g, Rhizoma Atractylodis Macrocephalae 5g, Radix Rehmanniae Preparata 20g, Radix Scrophulariae 5g, Poria 20g, Fructus Lycii 15g, Rhizoma Alismatis 20g, Fructus Corni 12g, Fructus Amomi 15g, Squama Manis 6g, Radix Glycyrrhizae 5g.
Embodiment 5
Treat a Chinese medicine composition for purpura, its raw material of Chinese medicine and weight proportion are: Radix Rehmanniae 40g, Radix Arnebiae (Radix Lithospermi) 5g, Rhizoma Imperatae 25g, Radix Isatidis 10g, Radix Sanguisorbae 20g, Radix Paeoniae Alba 5g, Radix Angelicae Sinensis 20g, Fructus Ligustri Lucidi 10g, Herba Ecliptae 25g, Flos Lonicerae 5g, Fructus Forsythiae 20g, Rhizoma Atractylodis Macrocephalae 10g, Radix Rehmanniae Preparata 25g, Radix Scrophulariae 12g, Poria 25g, Fructus Lycii 5g, Rhizoma Alismatis 25g, Fructus Corni 5g, Fructus Amomi 20g, Squama Manis 12g, Radix Glycyrrhizae 15g.
Chinese medicine composition in embodiment of the present invention decocting method is routinely produced medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and cover powder, soak 15~20 minutes, then add water and do not have approximately 6 centimetres of powder, decoct for the first time, adopt intense fire to decoct before at a simmer, after boiling with slow fire boiling 20~30 minutes; Decoct for the second time, add water and do not have approximately 4 centimetres of powder, after water boils, decoct 15~20 minutes.Decoct extracting juice twice, merge.
The present invention, with the given a kind of Chinese medicine composition for the treatment of purpura of embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation 80 cases, male 35 examples, female's 45 examples, 15~45 years old age.
Two, diagnosis basis:
(1), whole body or the visible point-like of extremity or speckle shape hemorrhage, do not exceed skin, repeatedly outbreak.Or hemorrhage speckle slightly exceeds skin, color is scarlet or dark red, and micro-itching can accompany the diseases such as stomachache or joint aches;
(2), can accompany low grade fever, bleeding from the gum, epistaxis, menorrhagia.Can there is headache in severe patient, stupor, has blood in stool, hematuria.
Three, usage and dosage: during clinical practice, potion on the one, the about 400ml of twice extracting juice of decocting, point morning, late twice empty stomach decoction being taken warmly.It within six days, is a course for the treatment of.Avoid cold and uncooked food during the treatment thing of pungent stimulation.
Four, criterion of therapeutical effect:
(1) cure: the purple point of purpura and General Symptoms disappear, and it is normal that lab index is recovered;
(2) effective: cyanosis of the skin speckle obviously reduces, and General Symptoms alleviates, and lab index is improved;
(3) invalid: cyanosis of the skin speckle, General Symptoms and lab index are all unchanged.
Five, therapeutic effect: in this clinical observation case, take medicine 2-6 the course for the treatment of, recovery from illness 52 examples, follow up a case by regular visits to and have no recurrence; Effective 20 examples, invalid 8 examples.During treatment, there is not toxic and side effects.
Six, model case:
Case 1:
Lee, man, 18 years old.After cat fever, on both legs skin, there are many purpuras, extremities joint swelling pain, and with stomachache, pale complexion, dizzy weak.Examine and see: pale tongue, white and thin fur, thready and stringy pulse.Be diagnosed as anaphylactoid purpura.Take 1 course for the treatment of of medicament prepared by Chinese medicine composition of the present invention, arthroncus is disappeared, and on lower limb, purpura is faded, and other symptoms alleviate; Continue to take 2 courses for the treatment of, all symptoms all disappear, and cure.
Case 2:
Bai, female, 27 years old.Before one week, without obviously inducement is unexpected, occurred that two lower limb and buttocks were dispersed in purpura, disease is seen patient's fatigue and weak, and two lower limb are heavy, constipation with dry stool, red tongue, yellow and thin fur, deep-thready pulse.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, purpura before alleviates, and does not occur new blue point again; Continue to take 2 courses for the treatment of, all symptoms disappear completely, cure.
Case 3:
Grandson, female, 42 years old.The two lower limb of patient play purpura, itch, and with stomachache, inappetence.Local hospital is diagnosed as: anaphylactoid purpura.Take after the Drug therapys such as antihistaminic and adrenocortical hormone transference cure.Obviously inducement disease relapse of nothing before 5 days.When medical, disease is seen the existing punctation of two skin of lower extremity, and shape differs and differs in size, a little higher than skin, the heat that occurs together, stomachache, anorexia.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, two lower limb, purpura color is thin out, and pruritus alleviates; Continue to take 2 courses for the treatment of, all diseases disappear, and cure.

Claims (2)

1. a Chinese medicine composition for the treatment of purpura, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: Radix Rehmanniae 10-40 part, Radix Arnebiae (Radix Lithospermi) 5-20 part, Rhizoma Imperatae 5-25 part, Radix Isatidis 5-25 part, Radix Sanguisorbae 5-20 part, Radix Paeoniae Alba 5-25 part, Radix Angelicae Sinensis 5-20 part, Fructus Ligustri Lucidi 5-25 part, Herba Ecliptae 5-25 part, Flos Lonicerae 5-20 part, Fructus Forsythiae 5-20 part, Rhizoma Atractylodis Macrocephalae 5-25 part, Radix Rehmanniae Preparata 5-25 part, Radix Scrophulariae 5-20 part, Poria 5-25 part, Fructus Lycii 5-20 part, Rhizoma Alismatis 5-25 part, Fructus Corni 5-20 part, Fructus Amomi 5-20 part, Squama Manis 5-20 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of purpura according to claim 1, is characterized in that: its raw material of Chinese medicine and weight portion proportioning are: 25 parts, the Radix Rehmanniae, 10 parts of Radix Arnebiae (Radix Lithospermi)s, 15 parts of Rhizoma Imperataes, 15 parts of Radix Isatidis, 10 parts of Radix Sanguisorbaes, 15 parts of the Radix Paeoniae Albas, 10 parts of Radix Angelicae Sinensis, 15 parts of Fructus Ligustri Lucidi, 15 parts of Herba Ecliptaes, 10 parts of Flos Loniceraes, 10 parts of Fructus Forsythiaes, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts, Radix Rehmanniae Preparata, 10 parts of Radix Scrophulariaes, 15 parts of Poria, 10 parts of Fructus Lyciis, 15 parts of Rhizoma Alismatis, 10 parts of Fructus Corni, 10 parts of Fructus Amomis, 10 parts of Squama Maniss, 10 parts, Radix Glycyrrhizae.
CN201410011769.3A 2014-01-11 2014-01-11 Traditional Chinese medicine composition for treating purpura Pending CN103735991A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173812A (en) * 2014-09-04 2014-12-03 纪雪梅 Pharmaceutical composition for treating blood-heat bleeding type acute idiopathic thrombocytopenic purpura and preparation method of pharmaceutical composition

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101658643A (en) * 2009-09-15 2010-03-03 刘锋 Medicament for treating allergic purpura

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101658643A (en) * 2009-09-15 2010-03-03 刘锋 Medicament for treating allergic purpura

Non-Patent Citations (1)

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Title
童亚芳等: "周信有教授治疗小儿紫癜经验", 《中医儿科杂志》, vol. 3, no. 3, 31 May 2007 (2007-05-31), pages 2 - 4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104173812A (en) * 2014-09-04 2014-12-03 纪雪梅 Pharmaceutical composition for treating blood-heat bleeding type acute idiopathic thrombocytopenic purpura and preparation method of pharmaceutical composition

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