CN103251797B - A kind of traditional Chinese medicine composition for treating burns and scalds and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating burns and scalds, which mainly comprises rehmannia root, dwarf lilyturf tuber, Chinese magnoliavine fruit, figwort root, common anemarrhena rhizome, honeysuckle flower, silktree albizzia bark, sinkiang arnebia root, catechu, dalbergia wood, menthol, aloe gel and white vaseline.

Description

A kind of traditional Chinese medicine composition for treating burns and scalds and preparation method thereof

technical field

The invention discloses a traditional Chinese medicine composition, especially a traditional Chinese medicine composition for treating burns and scalds and a preparation method thereof. The invention belongs to the field of traditional Chinese medicine.

Background technique

Burns and scalds are common accidental injuries in life. It is a kind of damage to the human body due to strong heat, so that the skin and flesh rot. In mild cases, only the skin and flesh are damaged; in severe cases, not only the skin and flesh are damaged, but also the fire and poison are blazing, injuring the Yin fluid in the body, or invading the blood, attacking the viscera internally, resulting in the disharmony of the viscera and viscera, and the balance of yin and yang. Severe burns can even be life-threatening if not treated in time.

Baili Tart Burn Treatment Center believes that according to the severity of the burn, it is mainly judged according to the location of the burn, the size of the area and the depth of the burn. Burns on the head and face, or those not on the head and face but with large and deep burns are considered severe. According to the depth, burns and scalds are generally divided into three degrees: 1. I degree burns: only the epidermis is injured, the injured skin is red and swollen, and it feels hot and painful, but no blisters appear; 2. .Second degree burns: damage to the dermis, local redness, swelling, fever, unbearable pain, and obvious blisters; 3. III degree burns: full-thickness skin, including fat, bone and muscle under the skin, are damaged, the skin is burnt black, Necrosis, the pain is not severe at this time, because many nerves are also damaged together.

Most of the medicines for the treatment of burns and scalds now have a single prescription, a single treatment range, and unsatisfactory effects, which often leave the wounded with hard-to-eliminate scars, increase the psychological burden of the wounded, and the cost of treatment is high, which increases the patient's life. economic burden.

Contents of the invention

In view of the above deficiencies, one of the objectives of the present invention is to provide a traditional Chinese medicine composition for treating burns and scalds, which has the characteristics of remarkable curative effect, no toxic and side effects, and can remove scars relatively completely. Raw material, low cost.

Another object of the present invention is to provide the above-mentioned preparation method for treating burns and scalds.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

A traditional Chinese medicine composition for treating burns and scalds. The preferred proportion is prepared from the main raw materials in the following weight proportions: 9-15 parts of rehmannia glutinosa, 6-12 parts of Radix Ophiopogon japonicus, 1.5-6 parts of Schisandra chinensis, and 9 parts of Scrophulariaceae -15 parts, 6-12 parts of Anemarrhena, 6-15 parts of honeysuckle, 6-12 parts of Albizia bark, 5-9 parts of comfrey, 1-3 parts of catechu, 9-15 parts of Dalbergia, 0.02-0.1 parts of menthol 2-6 parts of aloe vera gel, appropriate amount of white petrolatum.

A traditional Chinese medicine composition for treating burns and scalds, more preferably prepared by taking the main raw materials in the following weight ratios: 10-14 parts of rehmannia glutinosa, 8-10 parts of Radix Ophiopogon japonicus, 2-4 parts of Schisandra chinensis, and Scrophularia scrophulariae 10-14 parts, 8-10 parts of Anemarrhena, 8-12 parts of honeysuckle, 8-10 parts of Albizia juniper, 6-8 parts of comfrey, 1.5-2.5 parts of catechu, 10-13 parts of Jiangxiang, 0.05- menthol 0.09 parts, 3-5 parts of aloe vera gel, appropriate amount of white petrolatum.

A traditional Chinese medicine composition for treating burns and scalds. The optimal proportion is prepared from the main raw materials in the following weight proportions: 12 parts of rehmannia glutinosa, 9 parts of Radix Ophiopogon japonicus, 3 parts of Schisandra chinensis, 12 parts of Scrophulariaceae, and 9 parts of Anemarrhena , 10 parts of honeysuckle, 9 parts of acacia bark, 7 parts of comfrey, 2 parts of catechu, 11 parts of balsamic, 0.06 parts of menthol, 4 parts of aloe vera gel, and appropriate amount of white petrolatum.

A preparation method of a traditional Chinese medicine composition for treating burns and scalds, the preparation steps are as follows:

① Put Rehmannia glutinosa, Ophiopogon japonicus, Schisandra chinensis, Scrophulariaceae, Anemarrhena, and honeysuckle in a non-iron container, add water and decoct twice, the first time is 40 minutes, the second time is 30 minutes, the two filtrates are combined, and then Fry until the remaining 200 ml of liquid medicine is passed through a mesh sieve;

② Grind Albizia Julibrissin, Comfrey, Catechin, and Dalbergia into powder, and sieve through a mesh;

③ Add the powder ground in ② to the liquid medicine decocted in ①, and add an appropriate amount of white petrolatum, stir evenly until the liquid becomes a thick paste, seal it and let it stand;

④ After standing still, add aloe vera gel and menthol, stir evenly again, seal and let stand to fully integrate the active ingredients.

In the preparation method of the above-mentioned traditional Chinese medicine composition, step ① add 3000-6000 milliliters of water and decoct twice (preferably 4000-5500 milliliters, more preferably 5000 milliliters).

In the preparation method of the above-mentioned Chinese medicine composition, step ① the medicinal liquid is passed through a 10-14 mesh sieve (preferably a 12 mesh sieve).

In the preparation method of the above-mentioned traditional Chinese medicine composition, step ② passes through a 10-16 mesh sieve (preferably a 14 mesh sieve).

In the preparation method of the above-mentioned traditional Chinese medicine composition, step ③ stirs until the medicinal liquid becomes a thick paste, seals and stands still for 15-30 hours (preferably 18-25 hours, more preferably 20 hours).

Above-mentioned preparation method in Chinese medicine composition, step 4. seal and stand for 10-20 hours (preferably 14-18 hours, more preferably 16 hours).

Method of use: In order to achieve the best therapeutic effect of the present invention, take an appropriate amount and apply it evenly on the burns and scalds every morning and evening.

A traditional Chinese medicine composition for treating burns and scalds, the pharmacological effects of each bulk drug are respectively:

Rehmannia glutinosa: sweet in taste, cold in nature. It has the effects of clearing away heat and promoting body fluid, cooling blood and stopping bleeding, and is used for febrile disease and yin deficiency, crimson tongue and polydipsia, and internal heat due to yin deficiency.

Ophiopogon japonicus: sweet in taste, slightly cold in nature. It has the effects of nourishing yin and promoting body fluid, moisturizing the lungs and clearing the heart. It is used for dry cough, upset and insomnia, internal heat and thirst.

Fructus Schisandra: sour in taste, sweet in taste, warm in nature. It has the effects of astringent and astringent, nourishing qi and promoting body fluid, invigorating the kidney and calming the heart, and is used for chronic cough and dyspnea, and short qi and pulse deficiency.

Radix Scrophulariae: sweet, bitter, slightly cold in nature. There is cooling blood and nourishing yin, the effect of purging fire and detoxification, used for febrile disease impairing yin, bone steaming and labor cough, carbuncle and sore tumefacting virus.

Anemarrhena: bitter, sweet, cold in nature. It has the effects of clearing heat and purging fire, promoting body fluid and moistening dryness, and is used for febrile diseases caused by exogenous pathogenesis, high fever and polydipsia, lung heat and dry cough.

Honeysuckle: sweet in the mouth, cold in nature. There is heat-clearing and toxic substances removing, the effect of dispelling wind-heat, is used for carbuncle swollen furuncle, pyretic toxin bloody dysentery, and febrile disease generates heat.

Albizia Albiziae: sweet in taste, mild in nature. It has the effects of relieving stagnation and calming the nerves, promoting blood circulation and reducing swelling, and is used for lung abscess sores, pain from falls, restlessness, depression and insomnia.

Comfrey: sweet in taste, cold in nature. It has the effect of cooling blood and promoting blood circulation, detoxifying and clearing rash. It is used for blood heat and poison, impermeable measles, sores, water and fire burns.

Catechu: bitter in taste, slightly cold in nature. It has the effect of reducing dampness, promoting granulation and astringing sores. It is used for ulcers, pain from falls, and traumatic bleeding.

Dalbergia: pungent in taste, warm in nature. It has the effects of promoting qi and blood circulation, relieving pain, and stopping bleeding. It is used for epigastric pain, liver depression and hypochondriac pain, injury from falls, and traumatic bleeding.

Menthol: It is a saturated cyclic alcohol obtained from peppermint oil. It is a direction medicine, flavoring medicine and carminative. It is used to produce a cool feeling on the skin or mucous membranes to relieve discomfort and pain.

Aloe Vera Gel: Extracted from the natural herbal plant "Aloe Vera" by "freeze stabilization" technology. It has the effect of healing wounds, stopping bleeding and draining pus, and eliminating scars.

White petrolatum: A semisolid mixture of various hydrocarbons obtained from petroleum. For pharmaceutical excipients, lubricants, ointment mechanisms.

Burns are caused by fire and poison, and belong to the category of "sore ulcers" in traditional Chinese medicine. The ancients called them "fire sores" or "soup scald sores". The main pathogenesis of this disease is local blood fatigue and internal resistance, stagnation of meridians, and flaming heat and toxin. Therefore, in the treatment, the method of promoting blood circulation, dispelling fatigue and dredging collaterals, clearing away heat, detoxification and cooling blood should be taken as the Dafa. The traditional Chinese medicine composition of the present invention is based on the principle of traditional Chinese medicine for treating burns and scalds. The selected Chinese medicinal materials can effectively stop bleeding and relieve pain, eliminate scars, and have low cost. Long-term use will not cause economic burden to patients. It is an ideal medicine for treating burns and scalds. .

Detailed ways

The technical solutions of the present invention will be described in detail below in conjunction with the examples and experimental examples, but the scope of protection is not limited thereto.

Embodiment 1 A traditional Chinese medicine composition for treating burns and scalds. The following Chinese medicine raw materials are taken: 9 grams of rehmannia glutinosa, 6 grams of Radix Ophiopogon japonicus, 1.5 grams of Schisandra chinensis, 9 grams of Radix Scrophulariae, 6 grams of Anemarrhena anemarrhena, 6 grams of honeysuckle, and 6 grams of Cortex Albiziae , 5 grams of comfrey, 1 gram of catechu, 9 grams of balsamic, 0.02 grams of menthol, 2 grams of aloe vera gel, and an appropriate amount of white petrolatum.

The preparation method of above-mentioned Chinese medicine composition, the step is:

①Put Rehmannia glutinosa, Ophiopogon japonicus, Schisandra chinensis, Scrophularia scrophulariae, Anemarrhena, and honeysuckle in a non-iron container, add 3000 ml of water and decoct twice, the first time is 40 minutes, the second time is 30 minutes, and the two filtrates are combined , and then decocted until the remaining 200 ml of the liquid medicine was passed through a 10-mesh sieve;

② Grind Albizia Julibrissin, Comfrey, Catechin, and Dalbergia into powder, and pass through a 10-mesh sieve;

③ Add the ground powder in ② to the decocted medicinal liquid in ①, and add appropriate amount of white vaseline, stir evenly until the medicinal liquid becomes a thick paste, seal and let stand for 15 hours;

④ After standing still, add aloe vera gel and menthol, stir again, seal and let stand for 10 hours to fully integrate the active ingredients.

Typical case one Zhao XX, 22 years old, female, Dongchangfu District, Liaocheng City, Shandong Province. Symptoms: The backs of both feet of the patient were scalded by boiling water, which is a superficial second-degree burn, accompanied by red, swollen blisters and peeling in some parts. Visiting time: April 5, 2012. After debridement, the pain of the scalded area was significantly relieved after applying the traditional Chinese medicine composition of the present invention. After 4 days, some wounds began to congeal; 15 days later, the wound was completely healed without leaving any scars.

Embodiment 2 A traditional Chinese medicine composition for treating burns and scalds. The following traditional Chinese medicine raw materials are taken: 10 grams of rehmannia root, 8 grams of Radix Ophiopogon japonicus, 2 grams of Schisandra chinensis, 10 grams of Radix Scrophulariae, 8 grams of Anemarrhena anemarrhena, 8 grams of honeysuckle, and 8 grams of Cortex Albiziae , 6 grams of comfrey, 1.5 grams of catechin, 10 grams of balsamic, 0.05 grams of menthol, 3 grams of aloe vera gel, and an appropriate amount of white petrolatum.

The preparation method of above-mentioned Chinese medicine composition, the step is:

①Put Rehmannia glutinosa, Ophiopogon japonicus, Schisandra chinensis, Scrophulariaceae, Anemarrhena, and honeysuckle in a non-iron container, add 4000 ml of water and decoct twice, the first time is 40 minutes, the second time is 30 minutes, and the two filtrates are combined , and then decocted until the remaining 200 ml of the liquid medicine was passed through a 12-mesh sieve;

② Grind Albizia Julibrissin, Comfrey, Catechin, and Dalbergia into powder, and pass through a 12-mesh sieve;

③ Add the ground powder in ② to the decocted medicinal liquid in ①, and add an appropriate amount of white vaseline, stir evenly until the medicinal liquid becomes a thick paste, seal and let stand for 18 hours;

④ After standing still, add aloe vera gel and menthol, stir again, seal and let stand for 14 hours to fully integrate the active ingredients.

Typical Case 2 Liu XX, 5 years old, male, Qingyun County, Dezhou City, Shandong Province. Symptoms: The patient accidentally put his right hand into a charcoal stove, the wound turned burnt yellow, and branched blood vessels could be seen in the deep layer. It was diagnosed as a deep second-degree burn. Visiting time: February 15, 2012. After debridement of the wound, the traditional Chinese medicine composition of the present invention was evenly applied, the wound was exposed, and within 5 days, supplementary drug treatment was given to the exudate site, and anti-inflammatory rehydration treatment was given intravenously. The pain symptoms were significantly relieved on the same day, and the wound began to heal after 8 days, and the wound was completely healed after 35 days, leaving no scar tissue.

Embodiment 3 A traditional Chinese medicine composition for treating burns and scalds. The following traditional Chinese medicine raw materials are taken: 14 grams of rehmannia root, 10 grams of Radix Ophiopogon japonicus, 4 grams of Schisandra chinensis, 14 grams of Radix Scrophulariae, 10 grams of Anemarrhena anemarrhena, 12 grams of honeysuckle, 10 grams of Albizia juniper , 8 grams of comfrey, 2.5 grams of catechin, 13 grams of balsamic, 0.09 grams of menthol, 5 grams of aloe vera gel, and an appropriate amount of white petrolatum.

The preparation method of above-mentioned Chinese medicine composition, the step is:

①Put Rehmannia glutinosa, Ophiopogon japonicus, Schisandra chinensis, Scrophularia scrophulariae, Anemarrhena anemarrhena, and honeysuckle in a non-iron container, add 5500 ml of water and decoct twice, the first time is 40 minutes, the second time is 30 minutes, and the two filtrates are combined , and then decocted until the remaining 200 ml of the liquid medicine was passed through a 12-mesh sieve;

② Grind Albizia Julibrissin, Comfrey, Catechin, and Dalbergia into powder, and pass through a 16-mesh sieve;

③ Add the powder ground in ② to the liquid medicine decocted in ①, and add an appropriate amount of white vaseline, stir evenly until the liquid becomes a thick paste, seal and let stand for 25 hours;

④ After standing still, add aloe vera gel and menthol, stir again, seal and let stand for 16 hours to fully integrate the active ingredients.

Embodiment 4 A traditional Chinese medicine composition for treating burns and scalds. The following traditional Chinese medicine raw materials are taken: 15 grams of rehmannia glutinosa, 12 grams of Ophiopogon japonicus, 6 grams of Schisandra chinensis, 15 grams of Scrophulariae scrophulariae, 12 grams of Anemarrhena anemarrhena, 15 grams of honeysuckle, and 12 grams of Albizia juniper , comfrey 9 grams, catechin 3 grams, balsamic 15 grams, menthol 0.1 grams, aloe vera gel 6 grams, white petrolatum amount.

The preparation method of above-mentioned Chinese medicine composition, the step is:

①Put Rehmannia glutinosa, Ophiopogon japonicus, Schisandra chinensis, Scrophularia scrophulariae, Anemarrhena anemarrhena, and honeysuckle in a non-iron container, add 6000 ml of water and decoct twice, the first time is 40 minutes, the second time is 30 minutes, and the two filtrates are combined , and then decocted until the remaining 200 ml of the liquid medicine was passed through a 14-mesh sieve;

② Grind Albizia Julibrissin, Comfrey, Catechin, and Dalbergia into powder, and pass through a 16-mesh sieve;

③ Add the ground powder in ② to the decocted medicinal liquid in ①, and add an appropriate amount of white vaseline, stir evenly until the medicinal liquid becomes a thick paste, seal and let stand for 30 hours;

④ After standing still, add aloe vera gel and menthol, stir again, seal and let stand for 20 hours to fully integrate the active ingredients.

Typical case Sanma XX, 12 years old, male, Lanshan District, Linyi City, Shandong Province. Symptoms: The patient has a large area of burns on the chest, which accounts for about 15% of the total body area. The degree of burns ranges from superficial second degree to deep second degree. Symptoms such as blisters, peeling, redness and swelling appear at the wound, accompanied by severe pain. Visiting time: July 3, 2012. After debridement and application of the traditional Chinese medicine composition of the present invention, the patient stopped crying and the pain was significantly relieved. At the same time, he was given rehydration and anti-infection treatment. After 10 days of use, he suffered from superficial second-degree burns The site is completely scabbed, and the part of the deep second-degree scald part begins to scab. After 20 days of use, the superficial second-degree scald part is fully healed, and the deep second-degree scald part begins to heal. After 30 days of use, all parts are healed. No visible scars were left.

Example 5 A traditional Chinese medicine composition for treating burns and scalds. The following traditional Chinese medicine raw materials are taken: 12 grams of rehmannia root, 9 grams of Radix Ophiopogon japonicus, 3 grams of Schisandra chinensis, 12 grams of Radix Scrophulariae, 9 grams of Anemarrhena anemarrhena, 10 grams of honeysuckle, and 9 grams of Albizia juniper , 7 grams of comfrey, 2 grams of catechin, 11 grams of balsamic, 0.06 grams of menthol, 4 grams of aloe vera gel, and an appropriate amount of white petrolatum.

The preparation method of above-mentioned Chinese medicine composition, the step is:

①Put Rehmannia glutinosa, Ophiopogon japonicus, Schisandra chinensis, Scrophularia scrophulariae, Anemarrhena anemarrhena, and honeysuckle in a non-iron container, add 5000 ml of water and decoct twice, the first time is 40 minutes, the second time is 30 minutes, and the two filtrates are combined , and then decocted until the remaining 200 ml of the liquid medicine was passed through a 12-mesh sieve;

② Grind Albizia Julibrissin, Comfrey, Catechin, and Dalbergia into powder, and pass through a 14-mesh sieve;

③ Add the ground powder in ② to the decocted medicinal liquid in ①, and add an appropriate amount of white vaseline, stir evenly until the medicinal liquid becomes a thick paste, seal and let stand for 20 hours;

④ After standing still, add aloe vera gel and menthol, stir evenly again, seal and let stand for 16 hours to fully integrate the active ingredients.

Method of use: In order to achieve the best therapeutic effect of the present invention, take an appropriate amount and apply it evenly on the burns and scalds every morning and evening.

Experimental example

During December 2011-November 2012, 200 burn and scald patients in the outpatient department and inpatient department were selected as observation examples, and they were divided into two groups, the experimental group and the control group, and the experimental group used the Chinese medicine composition obtained in Example 5. , every morning and evening, take an appropriate amount and apply it evenly on the burns and scalds. The control group uses other medicines for treating burns and scalds. Both groups took 7 days as a course of treatment, and evaluated the curative effect after 6 courses of treatment.

The control group consisted of 100 cases, including 47 males and 53 females, aged from 1 to 55 years old, with an average age of 25.23±15.62 years old. Causes of injury: 53 cases of burns, 46 cases of boiling water burns, 1 case of oil burns, average burn area 11.32±8.60cm ² ; the experimental group consisted of 100 cases, 50 males and 50 females, aged from 18 months to 58 years, with an average age of 24.26±16.24 years. Causes of injury: burns in 50 cases, boiling water in 48 cases, oil There were 2 cases of burns, with an average burn area of 10.28±7.93cm ² . There was no significant difference between the two groups. All patients washed the wound with 0.9% sodium chloride injection in turn, and cut off the blisters if there were blisters; those with burns did not remove them, and disinfected with hydrogen peroxide.

Table 1: Comparison of clinical symptoms and signs before and after treatment in the two groups

Note: The burn area and healing days in the above table are the average.

Results: Comparing the evaluation of clinical symptoms and signs between the two groups before and after treatment, the two main efficacy indicators of the two groups of patients were improved after treatment, and the improvement effect of the experimental group was significantly better than that of the control group.

Through the clinical observation of the control group and the experimental group applying the traditional Chinese medicine composition to 200 patients with burns and scalds, it is proved that the experimental group has obvious advantages in the treatment of burns and scalds. According to case comparison, the traditional Chinese medicine composition of the present invention has remarkable effect on burns and scalds. For burns and scalds, it can significantly shorten the course of disease and reduce the amount of antibiotics used, thereby reducing costs. The effect is obvious, and the probability of skin grafting operations is significantly reduced. It has been proved by clinical tests that using the traditional Chinese medicine composition of the present invention can quickly achieve the purpose of pain relief, effectively accelerate wound healing, and relatively completely eliminate scars. It is a safe and effective traditional Chinese medicine composition for treating burns and scalds.

Claims (1)

1. treat a preparation method for the Chinese medicine composition of burn and scald, it is characterized in that, get following traditional Chinese medicine raw medicine: Radix Rehmanniae 12 grams, Radix Ophiopogonis 9 grams, Fructus Schisandrae Chinensis 3 grams, Radix Scrophulariae 12 grams, the Rhizoma Anemarrhenae 9 grams, Flos Lonicerae 10 grams, Cortex Albiziae 9 grams, Radix Arnebiae (Radix Lithospermi) 7 grams, 2 grams, catechu, Lignum Dalbergiae Odoriferae 11 grams, Mentholum 0.06 gram, Aloe glue 4 grams, white vaseline is appropriate; Step is:

1. by Radix Rehmanniae, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Scrophulariae, the Rhizoma Anemarrhenae, Flos Lonicerae is placed in non iron container, adds water 5000 milliliters and decocts twice, and first time is 40 minutes, and second time is 30 minutes, and twice filtrate merges, then decocts, and only more than 200 milliliters to medicinal liquid, 12 mesh sieves crossed by medicinal liquid;

2. by Cortex Albiziae, Radix Arnebiae (Radix Lithospermi), catechu, Lignum Dalbergiae Odoriferae pulverize, crosses 14 mesh sieves;

3. the powder of milled in is 2. added 1. in the medicinal liquid decocted, and add appropriate white vaseline, stir to medicinal liquid becomes thick paste, sealing and standing 20 hours;

4., after leaving standstill, add Aloe glue and Mentholum, again stir, sealing and standing 16 hours, makes effective ingredient fully merge.