CN103933367A - Traditional Chinese medicine formula of navel patch for treating atrophic gastritis and preparation method of traditional Chinese medicine formula - Google Patents

Traditional Chinese medicine formula of navel patch for treating atrophic gastritis and preparation method of traditional Chinese medicine formula Download PDF

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CN103933367A
CN103933367A CN201410184883.6A CN201410184883A CN103933367A CN 103933367 A CN103933367 A CN 103933367A CN 201410184883 A CN201410184883 A CN 201410184883A CN 103933367 A CN103933367 A CN 103933367A
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chinese medicine
parts
radix
medicine formula
traditional chinese
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CN103933367B (en
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邢建伟
苏秋菊
赵美玲
王多诚
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Qingdao Municipal Hospital
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Qingdao Municipal Hospital
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Abstract

The invention provides a traditional Chinese medicine formula of navel patch for treating atrophic gastritis and a preparation method of the of traditional Chinese medicine formula. The traditional Chinese medicine formula comprises dendrobe, citrus medica, costusroot, agilawood, basic fuchsin, hericium erinaceus, pig's gall bladder, medicated leaven, fried chicken gizzard-membrane, lindera aggregate, rhizoma acori graminei, root of straight ladybell and radix ophiopogonis. The navel patch disclosed by the invention provides an external treatment way for externally treating chronic atrophic gastritis by internal-use medicines, and is convenient, effective and not easy to relapse.

Description

A kind of Chinese medicine formula and preparation method for the treatment of the subsides of atrophic gastritis umbilicus
Technical field
The present invention relates to a kind of Chinese medicine formula, especially a kind of Chinese medicine formula and preparation method for the treatment of the subsides of atrophic gastritis umbilicus.
Background technology
Atrophic gastritis also claims chronic atrophic gastritis, with gastric epithelial and body of gland atrophy, and decreased number, gastric mucosa attenuation, mucosa basic unit thickens, or companion gland metaplasia and intestinal gland metaplasia, or to have atypical hyperplasia be the chronic digestive system disease of feature.Often show as epigastrium dull pain, distension, belch, inappetence, or become thin, anemia etc., without specificity.A kind of many paathogenic factors disease and precancerous lesion.The not effective especially medicine of western medical treatment chronic atrophic gastritis at present, just for some medicines of symptom.Treatment by Chinese herbs primary disease mostly is oral.
Summary of the invention
For obtaining the new and effective medicine applicable to treatment atrophic gastritis, the inventor, is paying after sufficient creative work, thereby is completing the present invention through a large amount of further investigations this.
The present invention relates to a kind of Chinese medicine formula for the treatment of atrophic gastritis, described Chinese medicine formula comprises Herba Dendrobii 17-20 part, fragrant Citron skin 12-15 part, Radix Aucklandiae 7-10 part, Lignum Aquilariae Resinatum 2-5 part, GUIZIHONG 5-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 6-9 part, Fel Sus domestica 3-6 part, Massa Medicata Fermentata 7-10 part, Endothelium Corneum Gigeriae Galli (parched) 7-10g part Radix Linderae 6-9 part, Rhizoma Acori Graminei 6-9 part, Radix Adenophorae (Radix Glehniae) 6-9 part, Radix Ophiopogonis 6-9 part.
Exemplify as one is exemplary, in described pharmaceutical composition, in weight portion, its concrete constituent content is as follows:
20 parts of Herba Dendrobiis, 12 parts of fragrant Citron skins, 10 parts of the Radix Aucklandiae, 2 parts of Lignum Aquilariae Resinatum, 5 parts of GUIZIHONG, 6 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 6 parts of Fel Sus domestica, 10 parts of Massa Medicata Fermentata, 10 parts of Endothelium Corneum Gigeriae Galli (parched)s, 6 parts of the Radixs Linderae, 6 parts of Rhizoma Acori Graminei, 6 parts of Radix Adenophorae (Radix Glehniae), 6 parts of Radix Ophiopogonis.
Umbilicus described above pastes, and its preparation method is: 1) take Pericarpium Citri, the Radix Aucklandiae, Lignum Aquilariae Resinatum extraction volatile oil by above-mentioned weight portion; 2) take other all kinds of medical material mix homogeneously according to above-mentioned weight portion, add the water of 10 times of volumes to boil, after boiling, changing little fire boils medicine 20 minutes again, the traditional Chinese medicine liquid boiling is poured in container, former medicinal residues add the water of 10 times of volumes to repeat to boil medicine again one time, and medicinal residues are outwelled, and the traditional Chinese medicine liquid boiling for twice is sneaked into evaporation together, unnecessary water evaporates is fallen, obtained the Chinese medicine preparation of picture paste; 3) in above-mentioned paste Chinese medicine preparation, add step 1) extract volatile oil, a certain amount of penetrating agent and wetting agent, be coated onto on non-woven fabrics, be prepared into umbilicus paste.
Described penetrating agent can be Oleum menthae, Fructus Citri Limoniae oil, Oleum Eucalypti, Oleum Caryophylli, Fructus Cnidii oil, Radix Angelicae Sinensis volatile oil, Lignum Pini Nodi wet goods.
Described wetting agent can be glycerol, vaseline, Cera Flava etc.
Umbilicus as above pastes, and its using method is: the treatment of external application umbilicus, paste 24 hours at every turn, the next day once.
Beneficial effect: umbilicus pastes as external preparation, and umbilicus is SHENQUE acupoint, and this cave is the center of body surface gravitational field, appearance material in human body is had to powerful spasm effect, is also the place that stomach wall is the thinnest, and acupuncture point has warming and tonifying primordial YANG, invigorating the spleen and stomach, the solid de-effect of recovery.Above-mentioned umbilicus pastes Chinese medicine formula multiselect promoting the circulation of QI to relieve pain, and the Chinese medicine of invigorating the spleen and regulating the stomach, is all that atrophic gastritis is had to obvious therapeutical effect in clinical middle proof.In this prescription, there are some Chinese medicines to there is volatility, add some simultaneously and there is volatile Chinese medicine and increased the transmitance to stomach wall, improved curative effect.Umbilicus of the present invention is provided by a kind of external treatment mode for the treatment of chronic atrophic gastritis except endo-medicine that provides.There is convenient, fast, effective advantage.Umbilicus of the present invention pastes and can use separately also and can be used in conjunction with existing endo-medicine, has improved therapeutic efficiency.
The property of medicine of main component:
1), Herba Dendrobii: meridian distribution of property and flavor: be slightly cold; Sweet; Return stomach, kidney channel
Function cures mainly: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Lose for cloudy impairment of body fluid, xerostomia excessive thirst, lack of appetite is retched, deficiency-heat after being ill, poor vision.
Herba Dendrobii has excitation to intestinal tube, can make shrinkage amplitude increase.Pharmacological testing shows, oral Herba Dendrobii decoct can promote gastric secretion, helps digest.Dendrobine similar to Fei Xiting drug effect and effect a little less than, Herba Dendrobii extractum can stimulate the contraction of intestinal smooth muscle, promote gastrointestinal peristalsis.Herba Dendrobii can be received the effect of uniqueness, satisfaction to chronic atrophic gastritis.In addition, Herba Dendrobii contains esters composition, has the effect that blood circulation promoting and blood stasis dispelling, blood vessel dilating and antiplatelet condense, and can improve the blood circulation of gastric tissue.
2) Pericarpium Citri:
Meridian distribution of property and flavor: pungent, sour, nontoxic.
Function cures mainly: the therapeutic method to keep the adverse QI flowing downwards, remove expectorant water, pain due to disorder of QI under the heart.This product is stomach invigorating purging medicine, for diseases such as dyspepsia, abundant expectoration uncomfortable in chest, vomitings; For chronic gastritis, nerve stomachache (peratodynia) is comparatively suitable.
This product is containing citric acid, vitamin (C, P), hesperidin, citric acid, malic acid, pectin, tannin.Better to chronic gastritis, nerve stomachache curative effect.Contained volatile oil has gentle stimulation to gastrointestinal tract, can promote to wriggle and digestive juice secretion in the intestines and stomach, gets rid of enteral pneumatosis, and has phlegm-dispelling functions.
3) Radix Aucklandiae:
Meridian distribution of property and flavor: pungent, bitter, temperature.Return spleen, stomach, large intestine, three warmers, gallbladder meridian
Function with cure mainly: promoting the circulation of QI to relieve pain, soothing the liver, the spleen invigorating of regulating the flow of vital energy disappear stagnant.
The pungent temperature of this product is fragrant loose, can rise and can fall, and leads to the gas of managing three warmers, and the especially gas of benefaction gastrointestinal and pain relieving has the merit of strengthening the spleen to promote digestion concurrently, and all cards are conventional product due to all taste QI stagnation of the large intestine.4) Lignum Aquilariae Resinatum:
Meridian distribution of property and flavor: pungent, bitter, temperature.Return spleen, stomach, kidney, lung meridian
Effect: sending down the abnormal ascending QI warming middle-JIAO, warming the kidney is supporing yang.
Cure mainly: control QI rising in reverse order and pant, vomiting singultus, abdominal distention, waist knee joint cold caused by deficiency,
Large intestine constipation due to insufficiency, urine qi stranguria, man's cold sperm.
The Radix Aucklandiae and Lignum Aquilariae Resinatum are used in conjunction with, and have the effect of QI invigorating circulation of qi promoting.
Detailed description of the invention
Below by specific embodiment, the present invention is described in detail; but the purposes of these exemplary embodiments and object are only used for exemplifying the present invention; not real protection scope of the present invention is formed to any type of any restriction, more non-protection scope of the present invention is confined to this.
Embodiment 1
Treat a Chinese medicine formula for atrophic gastritis, become (every part of 1g) by following component parts by weights array
17 parts of Herba Dendrobiis, 12 parts of fragrant Citron skins, 7 parts of the Radix Aucklandiae, 2 parts of Lignum Aquilariae Resinatum, 5 parts of GUIZIHONG, 6 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 3 parts of Fel Sus domestica, 7 parts of Massa Medicata Fermentata, 7 parts of Endothelium Corneum Gigeriae Galli (parched)s, 6 parts of the Radixs Linderae, 6 parts of Rhizoma Acori Graminei, 6 parts of Radix Adenophorae (Radix Glehniae), 6 parts of Radix Ophiopogonis.
Concrete preparation method is as follows:
1) take Pericarpium Citri, the Radix Aucklandiae, Lignum Aquilariae Resinatum extraction volatile oil by above-mentioned weight portion; 2) take other all kinds of medical material mix homogeneously according to above-mentioned weight portion, add the water of 10 times of volumes to boil, after boiling, changing little fire boils medicine 20 minutes again, the traditional Chinese medicine liquid boiling is poured in container, former medicinal residues add the water of 10 times of volumes to repeat to boil medicine again one time, and medicinal residues are outwelled, and the traditional Chinese medicine liquid boiling for twice is sneaked into evaporation together, unnecessary water evaporates is fallen, obtained the Chinese medicine preparation of picture paste; 3) in above-mentioned paste Chinese medicine preparation, add step 1) extract volatile oil, a certain amount of penetrating agent and wetting agent, be coated onto on non-woven fabrics, be prepared into umbilicus paste.
External application umbilicus treatment is pasted 24 hours at every turn, the next day once.
Embodiment 2
Treat a Chinese medicine formula for atrophic gastritis, become (every part of 1g) by following component parts by weights array
20 parts of Herba Dendrobiis, 15 parts of fragrant Citron skins, 10 parts of the Radix Aucklandiae, 5 parts of Lignum Aquilariae Resinatum, 8 parts of GUIZIHONG, 9 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 6 parts of Fel Sus domestica, 10 parts of Massa Medicata Fermentata, 9 parts of Endothelium Corneum Gigeriae Galli (parched) 10g part Radixs Linderae, 9 parts of Rhizoma Acori Graminei, 9 parts of Radix Adenophorae (Radix Glehniae), 9 parts of Radix Ophiopogonis.
Concrete preparation method and using method are with embodiment 1.
Embodiment 3
Treat a Chinese medicine formula for atrophic gastritis, become (every part of 1g) by following component parts by weights array
20 parts of Herba Dendrobiis, 12 parts of fragrant Citron skins, 10 parts of the Radix Aucklandiae, 2 parts of Lignum Aquilariae Resinatum, 5 parts of GUIZIHONG, 6 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 6 parts of Fel Sus domestica, 10 parts of Massa Medicata Fermentata, 10 parts of Endothelium Corneum Gigeriae Galli (parched)s, 6 parts of the Radixs Linderae, 6 parts of Rhizoma Acori Graminei, 6 parts of Radix Adenophorae (Radix Glehniae), 6 parts of Radix Ophiopogonis.
Concrete preparation method and using method are with embodiment 1.
Performance test:
Umbilicus of the present invention pastes the therapeutic efficiency to atrophic gastritis.
Subjects: 200, suffer from atrophic gastritis.
Test method:
200 patients are divided into two groups at random, i.e. oral medicine group 100 people, age 30-70 year, the course of disease 6 months-2 years; 100 people are organized in umbilicus subsides, age 28-68 year, the course of disease 7 months-2 years.
Brief summary: symptom is improved situation comparison.2 groups of patient's stomachache, abdominal distention, inappetence all improve significantly, but the relapse rate umbilicus subsides group after treatment is starkly lower than oral medicine group (in table 1).
Table 12 group patients with atrophic gastritis symptom is improved situation comparison [example (%)]
Case and clinical effectiveness:
Clinical practice and the effect of Chinese medicine formula of the present invention in treatment atrophic gastritis.
1) Mrs Liu, 55 years old, suffers from atrophic gastritis 3 years, time have stomach pain, anorexia abdominal distention, belch acid regurgitation, angry rear pain increases the weight of, constipation with dry stool; yellowish or reddish urine, red tongue, yellow and thin fur uses umbilicus subsides prepared by Chinese medicine formula of the present invention to treat after March; stomach pain is obviously alleviated, and appetite increases.Analyze: this type of patient violates stomach because of fire caused by depression of liver-QI, umbilicus prepared by Chinese medicine formula of the present invention pastes has dispersing the stagnated live-QI to relieve the stagnation of QI, and effect of regulating QI to relieve pain, reaches therapeutic effect.
2) Mrs Li, 43 years old, suffers from atrophic gastritis 2 years.Patient has gastralgia for many years time, mostly is twinge, and pain is paroxysmal, and pain very reflexes to the shoulder back of the body, thirsty, poor appetite, and large dry stool, yellow urine, tongue is dark red, and there is ecchymosis on tongue limit, yellow and thin fur, hesitant pulse.Use umbilicus prepared by Chinese medicine formula of the present invention to paste treatment after 3 months, after medication, pain of gastric cavity obviously alleviates, and without thirsty, two is just normal, patient's transference cure, clinical cure.Resolve: this type of patient is because of the with the passing of time hyperamization stasis of blood of the stagnation of QI, and umbilicus prepared by Chinese medicine formula of the present invention pastes has promoting flow of QI and blood, and effect of removing obstruction in the collateral to relieve pain, reaches therapeutic effect.
3) Mr. Liu, 48 years old.Suffer from atrophic gastritis 2 years, time have stomach to have a dull ache, in stomach, have noisy sense.Companion's dry mouth and tougue, hyperhidrosis, especially night hyperhidrosis, agitation, becomes thin, umbilicus prepared by weak Chinese medicine formula of the present invention pasted after 3 months, patient's stomach pain and noisy sense disappear, thirsty without xerostomia, perspire and weak sense alleviates, body weight increases.Resolve: for this type of deficiency of stomach-YIN disease, umbilicus prepared by Chinese medicine formula of the present invention pastes has YIN nourishing spleen invigorating, nourishing the stomach and in effect, reach therapeutic effect.
To sum up, umbilicus of the present invention pastes has lasting medicine, and the advantage that relapse rate is low, can together be used with oral drugs, improves the efficiency for the treatment of.
The purposes that should be appreciated that these embodiment only limits the scope of the invention for the present invention being described but not being intended to.In addition; also should understand; after having read technology contents of the present invention, those skilled in the art can make various changes, amendment and/or modification to the present invention, within these all equivalent form of values fall within the protection domain that the application's appended claims limits equally.

Claims (5)

1. treat the Chinese medicine formula that atrophic gastritis umbilicus pastes, described Chinese medicine formula comprises Herba Dendrobii, fragrant Citron skin, the Radix Aucklandiae, Lignum Aquilariae Resinatum, GUIZIHONG, Hericium erinaceus (Bull. Ex Fr.) Pers., Fel Sus domestica, Massa Medicata Fermentata, Endothelium Corneum Gigeriae Galli (parched), the Radix Linderae, Rhizoma Acori Graminei, Radix Adenophorae (Radix Glehniae), Radix Ophiopogonis.
2. Chinese medicine formula as claimed in claim 1, is characterized in that: in weight portion, its concrete constituent content is as follows:
Herba Dendrobii 17-20 part, fragrant Citron skin 12-15 part, Radix Aucklandiae 7-10 part, Lignum Aquilariae Resinatum 2-5 part, GUIZIHONG 5-8 part, Hericium erinaceus (Bull. Ex Fr.) Pers. 6-9 part, Fel Sus domestica 3-6 part, Massa Medicata Fermentata 7-10 part, Endothelium Corneum Gigeriae Galli (parched) 7-10g part Radix Linderae 6-9 part, Rhizoma Acori Graminei 6-9 part, Radix Adenophorae (Radix Glehniae) 6-9 part, Radix Ophiopogonis 6-9 part.
3. Chinese medicine formula as claimed in claim 1 or 2, is characterized in that: in weight portion, its concrete constituent content is as follows:
20 parts of Herba Dendrobiis, 12 parts of fragrant Citron skins, 10 parts of the Radix Aucklandiae, 2 parts of Lignum Aquilariae Resinatum, 5 parts of GUIZIHONG, 6 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 6 parts of Fel Sus domestica, 10 parts of Massa Medicata Fermentata, 10 parts of Endothelium Corneum Gigeriae Galli (parched)s, 6 parts of the Radixs Linderae, 6 parts of Rhizoma Acori Graminei, 6 parts of Radix Adenophorae (Radix Glehniae), 6 parts of Radix Ophiopogonis.
4. the Chinese medicine formula as described in claim 1-3, its preparation method is:
1) take Pericarpium Citri, the Radix Aucklandiae, Lignum Aquilariae Resinatum extraction volatile oil by above-mentioned weight portion;
2) take other all kinds of medical material mix homogeneously according to above-mentioned weight portion, add the water of 10 times of volumes to boil, after boiling, changing little fire boils medicine 20 minutes again, the traditional Chinese medicine liquid boiling is poured in container, former medicinal residues add the water of 10 times of volumes to repeat to boil medicine again one time, and medicinal residues are outwelled, and the traditional Chinese medicine liquid boiling for twice is sneaked into evaporation together, unnecessary water evaporates is fallen, obtained the Chinese medicine preparation of picture paste;
3) in above-mentioned paste Chinese medicine preparation, add step 1) volatile oil extracting, a certain amount of penetrating agent and wetting agent, be coated onto on non-woven fabrics, be prepared into umbilicus and paste.
5. Chinese medicine formula as claimed in claim 4, its using method is: umbilicus is pasted and outer spreads on patient's umbilicus, paste 24 hours at every turn, the next day once.
CN201410184883.6A 2014-05-05 2014-05-05 A kind of Chinese medicine preparation and preparation method who treats the subsides of atrophic gastritis navel Expired - Fee Related CN103933367B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853395A (en) * 2015-01-19 2016-08-17 王文联 Usage method of navel plaster
CN106074472A (en) * 2016-06-07 2016-11-09 胡淑贤 A kind of medicine treating alimentary canal inflammation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181617A (en) * 2007-12-04 2008-05-21 朱惠芬 Chinese medicine preparation for curing gastrointestinal disease
CN101229323A (en) * 2008-01-21 2008-07-30 邯郸制药有限公司 Lily oral liquid and quality standard and test method of pharmaceutical preparation thereof
CN102228660A (en) * 2011-07-04 2011-11-02 李久章 Medicine for treating gastrointestinal diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181617A (en) * 2007-12-04 2008-05-21 朱惠芬 Chinese medicine preparation for curing gastrointestinal disease
CN101229323A (en) * 2008-01-21 2008-07-30 邯郸制药有限公司 Lily oral liquid and quality standard and test method of pharmaceutical preparation thereof
CN102228660A (en) * 2011-07-04 2011-11-02 李久章 Medicine for treating gastrointestinal diseases

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853395A (en) * 2015-01-19 2016-08-17 王文联 Usage method of navel plaster
CN106074472A (en) * 2016-06-07 2016-11-09 胡淑贤 A kind of medicine treating alimentary canal inflammation

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