CN104042852A - Traditional Chinese medicine liquid with anesthesia effect and preparation method - Google Patents
Traditional Chinese medicine liquid with anesthesia effect and preparation method Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine liquid with an anesthesia effect and a preparation method. The traditional Chinese medicine liquid is mainly prepared from the following raw materials in parts by weight: 10-13 parts of cicada slough, 20-26 parts of corydalis tuber, 9-13 parts of pericarpium papaveris, 18-25 parts of myrrh, 5-9 parts of Scutellaria baicalensis, 11-14 parts of cuttlebone, 18-22 parts of camphor, 6-13 parts of dragon blood, 20-27 parts of Callicarpa bodinieri, 7-11 parts of radix clematidis and 16-25 parts of frankincense. The traditional Chinese medicine liquid provided by the invention is scientific in formula, low in price as the liquid is appropriately prepared from multiple pure natural Chinese medicine materials, convenient to use and free of toxic or side effect, and can take the effect into play rapidly to relieve the pain of patients, and the raw material medicines have good anesthesia and analgesia effects after being combined together.
Description
Technical field
The invention belongs to Chinese medicine goods field, specifically relate to a kind of traditional Chinese medicine liquid and preparation method with anesthesia effect, be mainly used in anesthesia and slow down pain.
Background technology
Anesthesia refers to make patient when undergoing surgery or have wound operation, not feel pain and uncomfortable state.It is generally acknowledged, anesthesia is that a kind of nervus centralis of being produced by medicine or additive method and (or) the reversibility function of peripheral nervous system suppress, and the feature of this inhibition is mainly to feel the particularly forfeiture of the pain sensation.Clinically, anesthesia mainly comprises general anesthesia and local anesthesia.General anesthesia refers to anesthetics is entered in body by suction, vein, intramuscular injection or rectal perfusion, and central nervous system is suppressed, and causes patient to realize and disappears and the process of the painless feel in the whole body.This anesthesia method is " sleeping state " as the saying goes, and feature is that patient realizes disappearance, and whole-body muscle is lax, experiences less than pain.The most frequently used general anesthesia mode is intubation and general anaesthesia, and feature is to adopt intravenous anesthetic or inhalation anesthetic to produce general anesthesia effect, needs circulation of qi promoting cannula in art, and mechanical assistance is breathed.Local anesthesia is to utilize local anesthetic as procaine, lignocaine etc., is injected at corresponding site spinal nerves, plexus nervorum or nerve trunk and the thinner peripheral termination of nerve are blocked, and a certain position of health is temporarily lost sensibility.The feature of local anesthesia is exactly " part " that anesthesia is confined to health, and patient's consciousness is regained consciousness.Conventional method comprises intravertebral anesthesia (retardance), nerve block, field block, local infiltration anesthesia and topical anesthesia etc.
In the pertinent literature of existing anesthesia Chinese medicine, Granted publication CN 102133323 B(application number 201110049132.X) Chinese patent literature discloses a kind of herbal anesthetic, raw material by following parts by weight is made: Venenum Bufonis 13-15 part, Radix Aconiti 8-13 part, Radix Aconiti Kusnezoffii 7-13 part, Pericarpium Zanthoxyli 20-25 part, Herba Asari 16-20 part, Radix Zanthoxyli 15-18 part, Borneolum Syntheticum 7-10 part, Folium Et Cacumen Murrayae 20-30 part, Herba Houttuyniae 4-6 part, Galla Chinensis 2-4 part, Folium Artemisiae Argyi 6-8 part, Rhizoma Paridis 4-6 part, Herba Taraxaci 4-6 part, Fructus Bruceae 4-6 part, Radix Notoginseng 100-130 part and 75% ethanol 600-700 part.Application publication number CN 103705791 A(application numbers 201410017120.2) Chinese patent literature discloses a kind of medicine for clinical anesthesia and preparation method, belongs to the field of Chinese medicines; The raw material of effective ingredient of the present invention consists of Venenum Bufonis, Caulis Spatholobi, Hex godajam (colebr) Wall, Moschus, Camphora, Herba Lycopodii, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Borneolum Syntheticum, Flos Daturae, the Radix Angelicae Dahuricae, Fructus Piperis Longi, Rhizoma Imperatae, Fructus Piperis, Rhizoma Arisaematis, Coriaria sinica and Radix Cirsii Japonici.
At present, the prior art that comprises above-mentioned patent documentation is in administration of anaesthetic and slow down aspect pain and remain deficiency, such as uncertain therapeutic efficacy is cut, with high costs, uses inconvenience etc.A kind of traditional Chinese medicine liquid with anesthesia effect is badly in need of in clinical practice.
Summary of the invention
For the deficiencies in the prior art, the object of the present invention is to provide a kind of effectively lenitive traditional Chinese medicine liquid and preparation method with anesthesia effect.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The traditional Chinese medicine liquid with anesthesia effect, contained Chinese medicine takes off the primary raw material of stating weight proportion and is prepared from: Periostracum Cicadae 10-13 part, Rhizoma Corydalis 20-26 part, Pericarpium Papaveris 9-13 part, Myrrha 18-25 part, Radix Scutellariae 5-9 part, Endoconcha Sepiae 11-14 part, Camphora 18-22 part, Sanguis Draxonis 6-13 part, Folium Callicarpae Formosanae 20-27 part, Radix Clematidis 7-11 part, Olibanum 16-25 part.
The above-mentioned traditional Chinese medicine liquid with anesthesia effect, preferred scheme, contained Chinese medicine takes off the primary raw material of stating weight proportion and is prepared from: Periostracum Cicadae 11-12 part, Rhizoma Corydalis 22-24 part, Pericarpium Papaveris 10-12 part, Myrrha 20-23 part, Radix Scutellariae 6-8 part, Endoconcha Sepiae 12-13 part, Camphora 19-21 part, Sanguis Draxonis 9-10 part, Folium Callicarpae Formosanae 22-25 part, Radix Clematidis 8-10 part, Olibanum 19-22 part.
The above has the traditional Chinese medicine liquid of anesthesia effect, better preferred scheme, and contained Chinese medicine takes off the primary raw material of stating weight proportion and is prepared from: 12 parts of Periostracum Cicadaes, 23 parts of Rhizoma Corydalis, 11 parts of Pericarpium Papaveriss, 22 parts of Myrrhas, 7 parts of Radix Scutellariaes, 13 parts of Endoconcha Sepiaes, 20 parts of Camphoras, 10 parts of Sanguis Draxonis, 24 parts of Folium Callicarpae Formosanae, 9 parts of Radix Clematidis, 21 parts of Olibanums.
According to the traditional Chinese medicine liquid described in arbitrary above with anesthesia effect, its preparation methods steps is as follows:
(1) get clean Periostracum Cicadae and Pericarpium Papaveris, slowly adding consumption is the refined honey that 0.3-0.5 doubly measures, and adds a cover moistening 25-45 minute (preferably 35 minutes), treat that sweet liquid inhales thoroughly, put in heat pot and constantly fry to buff, take loosen tack-free for spending, take out airing, pulverize, cross 60-100 mesh sieve;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools standbyly, pulverizes, and crosses 40-80 mesh sieve (preferably 60 mesh sieves);
(3) by weight the preferred 3:1 of 2-4:1() ratio get yellow wine and vinegar is mixed to get adjuvant, get clean Myrrha, Olibanum and Sanguis Draxonis, adding consumption is the adjuvant of 0.2-0.4 times of weight, slightly moistening, after liquid is sucked, be placed in marmite, with slow fire heating, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, standby, pulverize, cross 50-70 mesh sieve (preferably 60 mesh sieves);
(4) Rhizoma Corydalis, Folium Callicarpae Formosanae, Radix Scutellariae and Radix Clematidis are pulverized, cross 60-100 mesh sieve, after mixing with (1)-(3) gains, add 1-3 times of water gaging to decoct 2-4 hour (preferably 3 hours), centrifugalize, Camphora is smashed to pieces with supernatant and is mixed, add dehydrated alcohol to make to reach 50% containing alcohol amount, standing 50-130 minute, filters, and sterile packaged obtains target product.
According to preparation method recited above, preferred scheme is that step (1) is crossed 70-90 mesh sieve (preferably 80 mesh sieves).
According to preparation method recited above, preferably scheme is, 0.4 times of amount of consumption of step (1) refined honey.
According to preparation method recited above, preferred scheme is that the consumption of step (3) adjuvant is 0.3 times of amount.
According to preparation method recited above, preferred scheme is that step (4) is crossed 70-90 mesh sieve (preferably 80 mesh sieves).
According to preparation method recited above, preferred scheme is that step (4) amount of water is 2 times.
According to preparation method recited above, preferred scheme is that step (4) time of repose is 80-100 minute (preferably 90 minutes).
The traditional Chinese medicine liquid with anesthesia effect, the pharmacological effect of contained raw material is respectively:
Periostracum Cicadae: sweet, salty, cool.Return lung, Liver Channel.Effect: dispelling wind-heat, rash sore-throat relieving, expellings wind and relieving convulsion.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, cough hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, infantile convulsion is twitched, tetanus.
Rhizoma Corydalis: be the tuber of papaveraceae plant corydalis.Invigorate blood circulation, dissipating blood stasis, regulates the flow of vital energy, pain relieving.Control all pains of trusted subordinate's waist knee joint, menoxenia ， mass in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
Pericarpium Papaveris: sour, puckery, be slightly cold.Return lung, kidney, large intestine channel.The astringing intestine to stop diarrhea of astringing the lung, reinforces the kidney, pain relieving.Cure mainly chronic cough due to asthenia of viscera, pant, have loose bowels, dysentery, proctoptosis, seminal emission, leucorrhea, trusted subordinate and bones and muscles pain.
Myrrha: be the gum resin of olive subject plant myrrh or Alan fort myrrh.Loose blood blood stasis removing, subduing swelling and relieving pain.Control and fall damage, incised wound, muscles and bones, all Tong ， of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.
Radix Scutellariae: hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.Cure mainly hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Endoconcha Sepiae: be the inner shell of the multiple sepiellae seu sepiaes such as Sepiidae sepiella maindroni de Rochebrune, Sepia animal golden cuttlefish.Salty, puckery, temperature.Return liver, kidney channel.Astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness sore.Cure mainly haematemesis, hematemesis, metrorrhagia, has blood in stool, epistaxis, wound hemorrhage, emission due to deficiency of the kidney spermatorrhea, leucorrhea with red and white discharge, has a stomachache noisy, belch pantothenic acid, eczema ulcer.
Camphora: pungent, heat, mild toxicity.GUIXIN, spleen channel.Sensible ward off dirty, killing parasites for relieving itching, reducing swelling and alleviating pain.Cure mainly calentura coma, Sino-Russian dampinging off, acute filthy disease is vomited and diarrhoea and is suffered from abdominal pain, the disturbance of lower legs due to pathogenic cold and dampness, scabies stubborn dermatitis, tinea alba, chilblain, ecthyma, burn due to hot liquid or fire, traumatic pain, toothache, wind-fire acute conjunctivitis.
Sanguis Draxonis: be the resin in Palmae Daemonorops plant Sanguis Draxonis fruit and rattan.Sweet, salty, flat, mild toxicity.Dissipating blood stasis analgesic therapy, hemostasis, promoting tissue regeneration and ulcer healing.Cure mainly traumatic injury, ecchymoma due to internal injury, dysmenorrhea, postpartum stagnation stomachache, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time and hemorrhoid.
Folium Callicarpae Formosanae: be root and the leaf of Herba Verbenae Callicarpa plant Folium Callicarpae Macrophyllae.Pungent, bitter, flat.Return liver, spleen, stomach warp.Dissipating blood stasis hemostasis, reducing swelling and alleviating pain.Leaf: cure mainly haematemesis, spitting of blood, epistaxis, has blood in stool; External curing traumatic hemorrhage.Root: cure mainly treating swelling and pain by traumatic injury, rheumatic ostalgia.
Radix Clematidis: be the root and rhizome of Ranunculaceae Actions of Clematis Species Radix Clematidis, Clematis hexapetala, northeast clematis.Pungent, salty, micro-hardship, temperature, mild toxicity.Return bladder, Liver Channel.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Cure mainly rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, beriberi swells and ache, malaria, the bone larynx of choking with sobs.And control phlegm retention and gather.
Olibanum: the oleo-gum-resin of oozing out for skin zones such as Burseraceae Boswellia plant Boswellia carterii, Bao Da Boswellia carterii, wild Boswellia carteriis.Pungent, bitter, temperature.GUIXIN, liver, spleen channel.Invigorate blood circulation, circulation of qi promoting, pain relieving.Cure mainly trusted subordinate's pain, amenorrhea, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, traumatic injury stasis of blood pain, swollen ulcer drug, the sore being festered and unhealed.
Beneficial effect of the present invention is:
Traditional Chinese medicine liquid prescription science of the present invention, contained crude drug has good analgesia effectiveness through combination, by multiple natural Chinese medicines material, through the appropriate process of preparing Chinese medicine, is obtained, so the present invention is cheap, easy to use, and without any side effects, onset rapidly, alleviates patient's misery.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1the traditional Chinese medicine liquid with anesthesia effect, takes off the primary raw material of stating weight proportion and is prepared from (getting 16g for every part): 10 parts of Periostracum Cicadaes, 20 parts of Rhizoma Corydalis, 9 parts of Pericarpium Papaveriss, 18 parts of Myrrhas, 5 parts of Radix Scutellariaes, 11 parts of Endoconcha Sepiaes, 18 parts of Camphoras, 6 parts of Sanguis Draxonis, 20 parts of Folium Callicarpae Formosanae, 7 parts of Radix Clematidis, 16 parts of Olibanums.
The above-mentioned preparation method with the traditional Chinese medicine liquid of anesthesia effect, step is as follows:
(1) get clean Periostracum Cicadae and Pericarpium Papaveris, slowly adding consumption is the refined honey of 0.3 times of amount, adds a cover moistening 25 minutes, treats that sweet liquid inhales thoroughly, puts in heat pot and constantly fries to buff, take to loosen tack-free to be degree, to take out airing, pulverize, 60 mesh sieves;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools standbyly, pulverizes, and crosses 40 mesh sieves;
(3) by weight the ratio of 2:1, get yellow wine and vinegar is mixed to get adjuvant, get clean Myrrha, Olibanum and Sanguis Draxonis, adding consumption is the adjuvant of 0.2 times of weight, slightly moistening, after liquid is sucked, be placed in marmite, with slow fire heating, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, standby, pulverize, cross 50 mesh sieves;
(4) Rhizoma Corydalis, Folium Callicarpae Formosanae, Radix Scutellariae and Radix Clematidis are pulverized, cross 60 mesh sieves, after mixing with (1)-(3) gains, add 1 times of water gaging to decoct 2 hours, centrifugalize, Camphora is smashed to pieces with supernatant and is mixed, add dehydrated alcohol to make to reach 50% containing alcohol amount, standing 50 minutes, to filter, sterile packaged obtains target product.
typical case oneweek certain, man, 27 years old.Time accidentally isolate left hand the back of the hand in April, 2012 in work, darker because of wound, so be sent to hospital after first aid at the scene, sews up.Before operation, after doctor cleans out wound, get clean sponge and dip embodiment 1 gained herb liquid, spread upon gently wound, after 8 minutes, wound pain disappears, and suture operation normally carries out.
embodiment 2the traditional Chinese medicine liquid with anesthesia effect, takes off the primary raw material of stating weight proportion and is prepared from (getting 8g for every part): 13 parts of Periostracum Cicadaes, 26 parts of Rhizoma Corydalis, 13 parts of Pericarpium Papaveriss, 25 parts of Myrrhas, 9 parts of Radix Scutellariaes, 14 parts of Endoconcha Sepiaes, 22 parts of Camphoras, 13 parts of Sanguis Draxonis, 27 parts of Folium Callicarpae Formosanae, 11 parts of Radix Clematidis, 25 parts of Olibanums.
The above-mentioned preparation method with the traditional Chinese medicine liquid of anesthesia effect, step is as follows:
(1) get clean Periostracum Cicadae and Pericarpium Papaveris, slowly adding consumption is the refined honey of 0.5 times of amount, adds a cover moistening 45 minutes, treats that sweet liquid inhales thoroughly, puts in heat pot and constantly fries to buff, take to loosen tack-free to be degree, to take out airing, pulverize, 100 mesh sieves;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools standbyly, pulverizes, and crosses 40 mesh sieves;
(3) by weight the ratio of 4:1, get yellow wine and vinegar is mixed to get adjuvant, get clean Myrrha, Olibanum and Sanguis Draxonis, adding consumption is the adjuvant of 0.4 times of weight, slightly moistening, after liquid is sucked, be placed in marmite, with slow fire heating, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, standby, pulverize, cross 70 mesh sieves;
(4) Rhizoma Corydalis, Folium Callicarpae Formosanae, Radix Scutellariae and Radix Clematidis are pulverized, cross 100 mesh sieves, after mixing with (1)-(3) gains, add 3 times of water gagings to decoct 4 hours, centrifugalize, Camphora is smashed to pieces with supernatant and is mixed, add dehydrated alcohol to make to reach 50% containing alcohol amount, standing 130 minutes, to filter, sterile packaged obtains target product.
embodiment 3the traditional Chinese medicine liquid with anesthesia effect, takes off the primary raw material of stating weight proportion and is prepared from (getting 9g for every part): 11 parts of Periostracum Cicadaes, 22 parts of Rhizoma Corydalis, 10 parts of Pericarpium Papaveriss, 20 parts of Myrrhas, 6 parts of Radix Scutellariaes, 12 parts of Endoconcha Sepiaes, 19 parts of Camphoras, 9 parts of Sanguis Draxonis, 22 parts of Folium Callicarpae Formosanae, 8 parts of Radix Clematidis, 19 parts of Olibanums.
The above-mentioned preparation method with the traditional Chinese medicine liquid of anesthesia effect, step is as follows:
(1) get clean Periostracum Cicadae and Pericarpium Papaveris, slowly adding consumption is the refined honey of 0.3 times of amount, adds a cover moistening 25 minutes, treats that sweet liquid inhales thoroughly, puts in heat pot and constantly fries to buff, take to loosen tack-free to be degree, to take out airing, pulverize, 70 mesh sieves;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools standbyly, pulverizes, and crosses 40 mesh sieves;
(3) by weight the ratio of 2:1, get yellow wine and vinegar is mixed to get adjuvant, get clean Myrrha, Olibanum and Sanguis Draxonis, adding consumption is the adjuvant of 0.2 times of weight, slightly moistening, after liquid is sucked, be placed in marmite, with slow fire heating, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, standby, pulverize, cross 50 mesh sieves;
(4) Rhizoma Corydalis, Folium Callicarpae Formosanae, Radix Scutellariae and Radix Clematidis are pulverized, cross 70 mesh sieves, after mixing with (1)-(3) gains, add 1 times of water gaging to decoct 2 hours, centrifugalize, Camphora is smashed to pieces with supernatant and is mixed, add dehydrated alcohol to make to reach 50% containing alcohol amount, standing 80 minutes, to filter, sterile packaged obtains target product.
embodiment 4the traditional Chinese medicine liquid with anesthesia effect, takes off the primary raw material of stating weight proportion and is prepared from (getting 5g for every part): 12 parts of Periostracum Cicadaes, 24 parts of Rhizoma Corydalis, 12 parts of Pericarpium Papaveriss, 23 parts of Myrrhas, 8 parts of Radix Scutellariaes, 13 parts of Endoconcha Sepiaes, 21 parts of Camphoras, 10 parts of Sanguis Draxonis, 25 parts of Folium Callicarpae Formosanae, 10 parts of Radix Clematidis, 22 parts of Olibanums.
The above-mentioned preparation method with the traditional Chinese medicine liquid of anesthesia effect, step is as follows:
(1) get clean Periostracum Cicadae and Pericarpium Papaveris, slowly adding consumption is the refined honey of 0.5 times of amount, adds a cover moistening 45 minutes, treats that sweet liquid inhales thoroughly, puts in heat pot and constantly fries to buff, take to loosen tack-free to be degree, to take out airing, pulverize, 90 mesh sieves;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools standbyly, pulverizes, and crosses 80 mesh sieves;
(3) by weight the ratio of 4:1, get yellow wine and vinegar is mixed to get adjuvant, get clean Myrrha, Olibanum and Sanguis Draxonis, adding consumption is the adjuvant of 0.4 times of weight, slightly moistening, after liquid is sucked, be placed in marmite, with slow fire heating, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, standby, pulverize, cross 70 mesh sieves;
(4) Rhizoma Corydalis, Folium Callicarpae Formosanae, Radix Scutellariae and Radix Clematidis are pulverized, cross 90 mesh sieves, after mixing with (1)-(3) gains, add 3 times of water gagings to decoct 4 hours, centrifugalize, Camphora is smashed to pieces with supernatant and is mixed, add dehydrated alcohol to make to reach 50% containing alcohol amount, standing 100 minutes, to filter, sterile packaged obtains target product.
typical case twohuang, female, 54 years old.Grow cutaneous papilloma because of right side lower limb in June, 2013, surface is that nipple is outwards outstanding, sees many buttress shaft shape outthrust, goes to hospital to carry out excision, before operation, after doctor cleans out wound, get clean sponge and dip embodiment 4 gained herb liquids, spread upon gently lower limb affected part, right side, after 5 minutes, stimulate coating place, without pain, anesthesia onset.
embodiment 5the traditional Chinese medicine liquid with anesthesia effect, takes off the primary raw material of stating weight proportion and is prepared from (getting 12g for every part): 12 parts of Periostracum Cicadaes, 23 parts of Rhizoma Corydalis, 11 parts of Pericarpium Papaveriss, 22 parts of Myrrhas, 7 parts of Radix Scutellariaes, 13 parts of Endoconcha Sepiaes, 20 parts of Camphoras, 10 parts of Sanguis Draxonis, 24 parts of Folium Callicarpae Formosanae, 9 parts of Radix Clematidis, 21 parts of Olibanums.
The above-mentioned preparation method with the traditional Chinese medicine liquid of anesthesia effect, step is as follows:
(1) get clean Periostracum Cicadae and Pericarpium Papaveris, slowly adding consumption is the refined honey of 0.4 times of amount, adds a cover moistening 35 minutes, treats that sweet liquid inhales thoroughly, puts in heat pot and constantly fries to buff, take to loosen tack-free to be degree, to take out airing, pulverize, 80 mesh sieves;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools standbyly, pulverizes, and crosses 60 mesh sieves;
(3) by weight the ratio of 3:1, get yellow wine and vinegar is mixed to get adjuvant, get clean Myrrha, Olibanum and Sanguis Draxonis, adding consumption is the adjuvant of 0.3 times of weight, slightly moistening, after liquid is sucked, be placed in marmite, with slow fire heating, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, standby, pulverize, cross 60 mesh sieves;
(4) Rhizoma Corydalis, Folium Callicarpae Formosanae, Radix Scutellariae and Radix Clematidis are pulverized, cross 80 mesh sieves, after mixing with (1)-(3) gains, add 2 times of water gagings to decoct 3 hours, centrifugalize, Camphora is smashed to pieces with supernatant and is mixed, add dehydrated alcohol to make to reach 50% containing alcohol amount, standing 90 minutes, to filter, sterile packaged obtains target product.
experimental examplein order to verify that medicated sponge of the present invention has definite curative effect to the alleviation of anesthesia and pain in operation, patient's 216 examples of performing the operation during year August in August, 2011 to 2012 have been randomly drawed, male 124 examples wherein, female's 92 examples, age 22-74 year, body weight 50-75kg, patient is divided into experimental group and matched group at random, two groups are compared on age, sex, sick kind, Surgical Operation, and difference not statistically significant, has comparability.
Experimental group is got clean sponge and is dipped and with the embodiment of the present invention 5 gained, have the traditional Chinese medicine liquid of anaesthetizing effect patient is carried out to local anesthesia before operation and in operation, matched group carries out conventional preoperative preparation, and the patient who undergos surgery is carried out to the conventional anesthesia of subcutaneous injection medication (as procaine etc.).
By one, do not know that the doctor of the situation of dividing into groups observes and record patient's pain visual imitation assessment (VAS) of postoperative 8h, calculates and draw the meansigma methods of scoring.The case load that occurs untoward reaction after record anesthesia.
The observed result of experimental group and matched group is as shown in table 1:
Table 1
Observed result is analyzed: patient's pain visual imitation assessment (VAS) of the postoperative 8h of experimental group is significantly less than matched group, the patient of illustrative experiment group is starkly lower than matched group in postoperative pain, so traditional Chinese medicine liquid anaesthetic effect of the present invention is remarkable, and from untoward reaction generation statistical data, can find out, traditional Chinese medicine liquid of the present invention is without any side effects.
Claims (10)
1. the traditional Chinese medicine liquid with anesthesia effect, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Periostracum Cicadae 10-13 part, Rhizoma Corydalis 20-26 part, Pericarpium Papaveris 9-13 part, Myrrha 18-25 part, Radix Scutellariae 5-9 part, Endoconcha Sepiae 11-14 part, Camphora 18-22 part, Sanguis Draxonis 6-13 part, Folium Callicarpae Formosanae 20-27 part, Radix Clematidis 7-11 part, Olibanum 16-25 part.
2. the traditional Chinese medicine liquid according to claim 1 with anesthesia effect, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: Periostracum Cicadae 11-12 part, Rhizoma Corydalis 22-24 part, Pericarpium Papaveris 10-12 part, Myrrha 20-23 part, Radix Scutellariae 6-8 part, Endoconcha Sepiae 12-13 part, Camphora 19-21 part, Sanguis Draxonis 9-10 part, Folium Callicarpae Formosanae 22-25 part, Radix Clematidis 8-10 part, Olibanum 19-22 part.
3. the traditional Chinese medicine liquid according to claim 1 with anesthesia effect, is characterized in that, takes off the primary raw material of stating weight proportion and is prepared from: 12 parts of Periostracum Cicadaes, 23 parts of Rhizoma Corydalis, 11 parts of Pericarpium Papaveriss, 22 parts of Myrrhas, 7 parts of Radix Scutellariaes, 13 parts of Endoconcha Sepiaes, 20 parts of Camphoras, 10 parts of Sanguis Draxonis, 24 parts of Folium Callicarpae Formosanae, 9 parts of Radix Clematidis, 21 parts of Olibanums.
4. according to the preparation method of the arbitrary described traditional Chinese medicine liquid of claim 1-3, it is characterized in that, step is as follows:
(1) get clean Periostracum Cicadae and Pericarpium Papaveris, slowly adding consumption is the refined honey that 0.3-0.5 doubly measures, and adds a cover moistening 25-45 minute (preferably 35 minutes), treat that sweet liquid inhales thoroughly, put in heat pot and constantly fry to buff, take loosen tack-free for spending, take out airing, pulverize, cross 60-100 mesh sieve;
(2) get clean Endoconcha Sepiae and be placed in and forge in tank, upper cover one pannikin, commissure, with yellow mud sealing, is put several rice on pannikin, with slow fire grilling, wait a meter zoom Huang, after ceasing fire, takes out, and must forge Endoconcha Sepiae, cools standbyly, pulverizes, and crosses 40-80 mesh sieve (preferably 60 mesh sieves);
(3) by weight the preferred 3:1 of 2-4:1() ratio get yellow wine and vinegar is mixed to get adjuvant, get clean Myrrha, Olibanum and Sanguis Draxonis, adding consumption is the adjuvant of 0.2-0.4 times of weight, slightly moistening, after liquid is sucked, be placed in marmite, with slow fire heating, fry the aobvious glossy gloss to surface, taking-up is dried in the air cool, standby, pulverize, cross 50-70 mesh sieve (preferably 60 mesh sieves);
(4) Rhizoma Corydalis, Folium Callicarpae Formosanae, Radix Scutellariae and Radix Clematidis are pulverized, cross 60-100 mesh sieve, after mixing with (1)-(3) gains, add 1-3 times of water gaging to decoct 2-4 hour (preferably 3 hours), centrifugalize, Camphora is smashed to pieces with supernatant and is mixed, add dehydrated alcohol to make to reach 50% containing alcohol amount, standing 50-130 minute, filters, and sterile packaged obtains target product.
5. preparation method according to claim 4, is characterized in that, step (1) is crossed 70-90 mesh sieve (preferably 80 mesh sieves).
6. preparation method according to claim 4, is characterized in that, 0.4 times of amount of consumption of step (1) refined honey.
7. preparation method according to claim 4, is characterized in that, the consumption of step (3) adjuvant is 0.3 times of amount.
8. preparation method according to claim 4, is characterized in that, step (4) is crossed 70-90 mesh sieve (preferably 80 mesh sieves).
9. preparation method according to claim 4, is characterized in that, step (4) amount of water is 2 times.
10. preparation method according to claim 4, is characterized in that, step (4) time of repose is 80-100 minute (preferably 90 minutes).
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| CN102357223A (en) * | 2011-10-21 | 2012-02-22 | 安徽中医学院附属针灸医院 | Medicine for curing acute soft tissue injury and preparation method thereof |
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| CN102357223A (en) * | 2011-10-21 | 2012-02-22 | 安徽中医学院附属针灸医院 | Medicine for curing acute soft tissue injury and preparation method thereof |
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| 张彩山: "《中老年自我治病全书》", 31 August 2013, 天津科学技术出版社 * |
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| CN105943815A (en) * | 2016-06-13 | 2016-09-21 | 于小兵 | Medicine for clinical anesthesia and preparing method and application thereof |
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