CN104524535A - Traditional Chinese medicine composition for treating chronic pulmonary heart disease and preparation method of traditional Chinese medicine composition - Google Patents

Traditional Chinese medicine composition for treating chronic pulmonary heart disease and preparation method of traditional Chinese medicine composition Download PDF

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CN104524535A
CN104524535A CN201510026679.6A CN201510026679A CN104524535A CN 104524535 A CN104524535 A CN 104524535A CN 201510026679 A CN201510026679 A CN 201510026679A CN 104524535 A CN104524535 A CN 104524535A
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chinese medicine
rhizoma
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范丰双
葛翠萍
吴俊杰
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范丰双
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Abstract

The invention discloses a traditional Chinese medicine composition for treating a chronic pulmonary heart disease. The traditional Chinese medicine composition is prepared from the following raw materials by certain weight ratios: ephedra, cassia twig, rhizoma zingiberis, asarum, pinellia ternate, schisandra chinensis, white peony root, rhizoma belamcandae, semen lepidii, astragalus membranaceus, angelica sinensis, rhodiola rosea, gecko, agarwood, peach seed, flos carthami, ligusticum wallichii, salviae miltiorrhizae, spina gleditsiae, codonopsis pilosula, roasted rhizoma atractylodis macrocephalae, poria cocos and honey-fried licorice root. The traditional Chinese medicine composition has the efficacies of eliminating dampness, removing phlegm, freeing the lung, relieving asthma, nourishing the blood for tranquilization, supplementing qi and promoting the production of body fluid. The traditional Chinese medicine composition is capable of effectively treating the chronic pulmonary heart disease.

Description

A kind of Chinese medicine composition for the treatment of chronic pulmonary heart disease and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for the treatment of chronic pulmonary heart disease.The invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Chronic pulmonary heart disease causes lung tissue structure and dysfunction by the chronic disease of lung tissue, pulmonary artery or thorax, pulmonary vascular resistance is caused to increase, pulmonary artery pressure increases, and making right cardiectasis, hypertrophy, companion or do not accompany the heart disease of right heart failure, is commonly encountered diseases, frequently-occurring disease.Sicken age is many more than 40 years old, increase with the age and prevalence increases, cold district, highlands, rural area prevalence are high, and its protopathy is the most common with chronic bronchitis, emphysema, acute attack is common with winter-spring season, often brings out lung, cardiac insufficiency because of respiratory tract infection.Clinical manifestation is mainly: the symptom of lung primary disease, the sign of emphysema and right heart insufficiency and pulmonary encephalopathy etc., and during serious attack, dyspnea increases the weight of, limitation of activity, and appetite declines, and even occurs respiratory failure, right heart failure and threat to life.
Chronic pulmonary heart disease belongs to the categories such as traditional Chinese medical science the syndrome of dyspnea, phlegm retention, pulmonary distension, edema.First pathological change is the positive QI-insufficiency of body, lower for the resistance, pathogen invasion and attack human body, and lung is first by it, and mistake department falls in lung qi a surname, sends out as breathing with cough.If repeatedly experience pathogen, lung is felt frustrated weak, and phlegm retention is detained, and with the passing of time healthy energy must decline, and involve the heart further, spleen, kidney are all dirty.Lung wound with the passing of time must and in the heart, insufficiency of heart-QI be difficult to promote then to cause stagnation of heart-blood and see cardiopalmus, breast door, suppress breathe heavily, cyanosis, tongue be dim; The spleen has the function to transport and transform nutrients, dysfunction of the spleen in transportation, indigestion, raw in phlegm-damp, the above criminal's of gushing lung, and see that the amount of coughing up phlegm is many; The main water of kidney, suffers from a deficiency of the kidney and is difficult controlling the water circulation, the heart attacked by pathogenic water, then increase the weight of cardiopalmus, breathe hard; Kidney is main improving inspiration by invigorating kidney-QI again, the main breathing of lung, and lung qi descendingly should return kidney, and kidney qi has again takes the photograph the effect of lung qi received, if deficiency of kidney-QI can not be taken the photograph and receive lung qi, then sends out as dyspnea due to deficiency.Therefore, the generation of pulmonary heart disease, is lung, the heart, spleen, the dirty functional disorder of kidney four.
At present, treatment pulmonary heart disease does not have specific drug, most with antiinflammatory, cough-relieving, relieving asthma or treat with treating cardiopathic medicine, also can adopt diuresis if desired, expand blood vessel medicine and cardiac tonic, to improve the treatments such as ventilation, but effect is very undesirable, very easily recurrence and mortality rate is high, antibiotic use can only play interim symptom management, the interim threat that mitigate the disease is serious, can not fundamentally disease therapy.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has evident in efficacy for treatment chronic pulmonary heart disease, cheap, with strong points, has no side effect, the feature not easily recurred.
Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment chronic pulmonary heart disease.
Inventor is in clinical treatment practice for many years, observe the misery that chronic pulmonary heart disease brings to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula for the treatment of the Chinese medicine preparation of chronic pulmonary heart disease repeatedly, the present invention selects Herba Ephedrae, Ramulus Cinnamomi, Rhizoma Zingiberis, Herba Asari, the Rhizoma Pinelliae, Fructus Schisandrae Chinensis, the Radix Paeoniae Alba, Rhizoma Belamcandae, Semen Lepidii (Semen Descurainiae), the Radix Astragali, Radix Angelicae Sinensis, Radix Rhodiolae, Gecko, Lignum Aquilariae Resinatum, Semen Persicae, Flos Carthami, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Spina Gleditsiae, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae (parched), Poria, Radix Glycyrrhizae Preparata combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is dampness expectorant, depressed lung-energy dispersing, nourishing blood to tranquillize the mind, effect of supplementing QI for promoting the production of body fluid, thus effectively can treat chronic pulmonary heart disease.
The effect of Chinese medicine of the present invention:
Wherein:
Herba Ephedrae: be the dry herb stem of Ephedraceae plant plait Herba Ephedrae Ephedra sinica Stapf, epheday intermedia Ephedraintermedia Schrenk et C.A.Mey. or ephedra equisetina Ephedra equisetina Bge..Nature and flavor: pungent, micro-hardship, temperature.Return lung, urinary bladder channel.Effect: diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema.For anemofrigid cold, uncomfortable in chestly to breath with cough, edema due to wind pathogen edema; Bronchial asthma.Herba Ephedrae is warm in nature pungent loose, can diaphoresis cold expelling and inducing sweat, wind rash of can faling apart again.With the fever with chills controlled caused by affection of exogenous wind-cold, the disease such as lossless, normal and Ramulus Cinnamomi mutual reinforcement between is use, has the effect of relieving the exterior syndrome by diaphoresis.Thoroughly sending out smooth as controlled measles, when having cough symptom out of breath concurrently, can drink and adding Herba Ephedrae in letting eruptions out with drugs of pungent flavor and cool nature medicine, because of lung governing skin and hair, this product can lung qi dispersing, can disperse again, the effect of can receive rash, relievining asthma.
Ramulus Cinnamomi: be the dry twig of canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Effect: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Cure mainly exterior syndrome due to wind-cold; Arthralgia due to cold-dampnes; WEIJIA is lumpd; The thoracic obstruction; Cardiopalmus; Phlegm retention." Changsha medicine solution " carries: " enter liver man and promoting the circulation of blood divides, determine meridians and reach Rong Yu.Kind solution ailment said due to cold or exposure, adjusts wood gas most.The detrapping of sending up the lucid YANG, the punching of the turbid descending the moon is inverse, the anxious contraction of relaxing muscles and tendons feeling pulse; The heap soil or fertilizer over and around the roots resistance in profit joint, fall apart and suppress, pain relieving Chu, the meridian dredging, opens numbness puckery, very dries cold.Only renal mass, more pacifies palpitation with fear." modern medicine study confirm, Ramulus Cinnamomi can effectively blood vessel dilating, promote diaphoresis, contained cinnamic aldehyde, natrium cinnamicum have antipyretic, analgesia, calmness, anticonvulsant action, in addition Ramulus Cinnamomi antibacterial, antiviral effect in addition.Ramulus Cinnamomi is warm in nature, and the kind gas that activates yang, can change YIN-cold, temperature three-way meridian, for all pain cards of congealing cold with blood stasis.
Rhizoma Zingiberis: be the dry rhizome of zingiber Zingiber officinale Rosc..Nature and flavor: pungent, hot.Return spleen, stomach, the heart, lung meridian.Effect: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, warming the lung to resolve fluid-retention.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.
Herba Asari: be the dry herb of aristolochiaceae plant Herba Asari Asarum heterotropoides Fr.Schmidtvar.mandshuricum (Maxim.) Kitag., Seoul Herba Asari Asarum sieboldii Miq.var.seoulense Nakai or magnificent Herba Asari Asarum sieboldii Miq..Nature and flavor are pungent; Temperature; Mild toxicity.Return lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel.Effect: mass dissipating and swelling eliminating; Induce sweat cold expelling; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention; The therapeutic method to keep the adverse QI flowing downwards is eliminated the phlegm, sensible.Antibacterial, antivirus action kakuol preserved material, volatilization wet goods have certain In-vitro Inhibitory Effect to gram positive bacteria, bacillus subtilis and Bacillus typhi, and decoct also has inhibitory action to tubercule bacillus and Bacillus typhi.Herba Asari volatile oil is to multiple fungus as Aspergillus flavus, Aspergillus niger, Candida albicans etc. all have inhibitory action, and antibacterial effective ingredient is safrole.
The Rhizoma Pinelliae: be the tuber at the Rhizoma Arisaematis section plant Rhizoma Pinelliae (Pinellia ternata (Thunb.) Breit.).Nature and flavor are pungent, temperature, poisonous.Enter spleen, stomach warp.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.The pungent loose warm-dryness syndrome of these product is poisonous, main enter taste double enter lung, water of manageing it wets, lowering the adverse flow of QI, and kind taste damp-phlegm of dispelling.Water is wet to be gone, and the strong and sputum of spleen is from disappearing, and inverse gas falls then harmonization of the stomach and feeling of fullness vomiting from only, therefore is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the good medicine of dissolving lump and resolving mass.Both cure mainly the abundant expectoration cough with asthma QI rising in reverse order of spleen damp-phlegm heap soil or fertilizer over and around the roots, control again the dizzy palpitation and insomnia that damp-phlegm is violated." property of medicine opinion ": expectorant saliva, appetite promoting and the spleen strengthening, anti-nausea, go expectorant in the heart full, lower lung qi, master coughs knot.
Fructus Schisandrae Chinensis: be the dry mature fruit of magnoliaceae schisandra Schisandra chinensis (Turcz.) Baill. or schisandra chinensis Schisandra sphenanthera Rehd.et Wils..Nature and flavor: warm, sour, sweet.Return lung, the heart, kidney channel.Function: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
The Radix Paeoniae Alba: be the dry root of dicotyledon ranunculaceae plant Radix Paeoniae Paeonia lactiflora Pall..Nature and flavor: cool, picric acid, is slightly cold.Effect: easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving, yin fluid astringing receives antiperspirant.Research shows: the paeoniflorin contained in the Radix Paeoniae Alba has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.This product energy nourishing the liver blood, holding back liver-yin, subduing the hyperfunction of the liver sun, dispersing liver-energy, can delay again that contraction is anxious, relieve the pain pain, is the good medicine of the various pain for the treatment of Liver Channel.
Rhizoma Belamcandae: be the dry rhizome of irides Rhizoma Belamcandae Belamcanda chinensis (L.) DC..Nature and flavor: bitter, cold.Return lung meridian.Effect: heat-clearing and toxic substances removing, expectorant, sore-throat relieving.For the pent-up of pyretic toxicity phlegm-fire, laryngopharynx swelling and pain, accumulation and obstruction of sputum, cough and asthma.Except with except the medicine for expectorant, sore-throat relieving, also in order to eliminating mass abdominal mass, except malaria with splenomegaly, stimulate the menstrual flow and close in biejiajian pills.Another name is crow fan.Join Fructus Arctii or Radix Scutellariae, then relieving sore-throat by clearing away heat; As joined Herba Ephedrae, then eliminating phlegm to relieve asthma." Bencao Jingshu ": " Rhizoma Belamcandae, hardship can be let out down, therefore is apt to fall; Hold concurrently pungent, thus kind loose.Therefore main cough with dyspnea, sore throat pharyngalgia, must not message, and eliminating stagnation gas is evil inverse in the heart.Both fallen and fallen apart, benefit is to be slightly cold, therefore the large heat of staple food drink.
Semen Lepidii (Semen Descurainiae): be the dry mature seed of crucifer Lepidium sativum L. Lepidium apetalum Willd. or descurainia sophia (l.) webb ex prantl Descurainia sophia (L.) Webb ex prantl.Nature and flavor: pungent, bitter, Great Cold.Return lung, urinary bladder channel.Effect: eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema." Bencao Jingshu ": Semen Lepidii is the positive medicine of meridian of Hand-TAI YIN, thus Zhong Jing eliminating the pathogens from the lung soup with it, also start with sun bright, meridian of Foot-TAI YANG.The lung belonging to metal, main fur, bladder belongs to water, hides body fluid, and then bladder is with here for obstruction of lung-QI, and it is obstructed that the upper orifices of example closes then lower orifices, and lower orifices are obstructed, then water is wet overflows for dyspnea with fullness of the chest, for swelling, for gathering, all diease occurrences.Pungent energy falls apart, and hardship can be let out, and Great Cold is heavy cloudy can descendingly relieve oedema or abdominal distension through diuresis or purgation, thus can treat " herbal classic " lead all diseases.
The Radix Astragali: be the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch.) Bge.var.mongholicus (Bge.) Hsiao or Radix Astragali Astragalus membranaceus (Fisch.) Bge..Nature and flavor: sweet, tepor.Return lung, spleen, liver, kidney channel.Effect: tonifying Qi and lifting yang, consolidating superficial resistance arresting sweating, inducing diuresis to remove edema, the evacuation of pus of holder skin ulcer, regulating fluid apssage.This product all has inhibitory action to dysentery bacterium, anthrax bacillus, α-hemolytic streptococcus, beta hemolytic streptococcus, diphtheria corynebacterium, bacillus pseudodiphthericus, Diplococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, bacillus subtilis etc. in vitro.
Radix Angelicae Sinensis: be the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.Nature and flavor are sweet, pungent, bitter, temperature.Return liver, the heart, spleen channel.Effect: enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.Radix Angelicae Sinensis has inhibitory action to central nervous system, and volatile oil has the effects such as calmness, hypnosis, analgesia, anesthesia." Radix Astragali and Radix Angelicae Sinensis have the reason of mutual reinforcement between." gas of the large tonifying the lung spleen of the Radix Astragali, there is admittedly outer energy; Radix Angelicae Sinensis benefit blood and battalion are blood man gas medicines, with pungent elevator behavior use, with gentle Xin Run for merit.Two tastes close it, just can Yin grows while yang is generating, therefore damage traumatology disease in medical treatment wound, no matter Qi and blood deficiency, with or without heating, multiplexly to return, stilbene matches.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores.Carry according to " book on Chinese herbal medicine is just ": " its sweet in the mouth and weigh, therefore specially can enrich blood, its gas is light and pungent, therefore again can promoting the circulation of blood, can support nutrition blood, QI invigorating spermatogenesis, settling five organs, strong body, beneficial mind, all tangible deficient diseases, nothing unsuitable." modern medicine study confirmation, Radix Angelicae Sinensis has antibacterial, antiinflammation.
Radix Rhodiolae: be Crassulaceae Rhodida plant Radix Rhodiolae Rhodiola saera (Prain) Fu, with all herbal medicine.Nature and flavor: sweet, puckery, cold.Effect: QI invigorating lung heat clearing; Fructus Alpiniae Oxyphyllae is nourished heart; Hemostasis with astringents; Dissipating blood stasis for subsidence of swelling.Main deficiency of vital energy and physically weak; Fear of cold after being ill; Shortness of breath and fatigue; Cough due to lung-heat; Spitting of blood; Leucorrhea is suffered from diarrhoea; Traumatic injury; Burn and scald; Neurosis; Altitude sickness.
Gecko: be the dry body of Gekkonidae animal Gecko Gekko gecko Linnaeus.Nature and flavor: salty are flat.Return lung, kidney channel.Effect: invigorating the lung and the kidney, improving inspiration by invigorating kidney-QI Dingchuan, supporing yang benefit essence.For dyspnea due to deficiency tachypnea, chronic cough hemoptysis, impotence and seminal emission." Bencao Jingshu ": Gecko, its main lung impairment and cough of a specified duration, pouring drop person, all lung kidney is disease, and suffer from a deficiency of the kidney and heat-dissipating in labor pole then lung, therefore exopathogen is easily invaded, and internal evidence is held concurrently and sent out also.Gecko belongs to cloudy, can source on moisturizing, then lung kidney all institute is supported, and consumptive fever is coughed and is certainly removed; The convergence of vessels in the lung, regulating fluid apssage.Lower defeated bladder.Normal lung-QI, therefore drench dewatering road from leading to also.
Lignum Aquilariae Resinatum: for Isolated From Thymelaeaceae Species Lignum Aquilariae Resinatum Aquilaria sinensis (Lour.) Gilg contains the timber of resin.Nature and flavor: pungent, bitter, tepor.Return spleen, stomach, kidney channel.Effect: promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.For the vexed pain of breast abdominal distention, gastrofrigid vomiting singultus, QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration." medicineization justice ": Lignum Aquilariae Resinatum, pure sun and rising, body weight and sinking, acrid in the mouth is wandered away, and gas hero is walked crosswise, therefore has exceedingly high ability merit, controls all carbuncles of thoracic dorsal extremity and skin pruritus.And fragrant energy replenishing vital QI with drugs of warm nature internal organs, protect and defend gas.If cold-damp is stagnant in bottom, helps with this and relax through medicine, kind expulsion pathogen; If injury from falling down, help and blood medicine with this, the analgesic therapy of energy dissipating blood stasis; If strange all diseases, help with this and attack expectorant medicine, can calm the nerves by sending down the abnormal ascending QI.In a word, dredging the meridian, blood is capable with gas, and expectorant is with cyclostrophic, and all genus sufferings, know more invariably.
Semen Persicae: be the dry mature seed of rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunusdavidiana (Carr.) Franch..Nature and flavor: bitter, sweet, flat.GUIXIN, liver, large intestine channel.Effect: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma.The power of Semen Persicae blood stasis dispelling is comparatively strong, also known as stasis-breaking drug, is used for the treatment of blood stasis, WEIJIA, often joins Flos Carthami, Radix Angelicae Sinensis.Semen Persicae is improved effect to blood flow retardance, blood obstacle, and each internal organs can be made respectively to organize functional recovery normal.
Flos Carthami: be the tubular corolla of feverfew Flos Carthami Carthamus tinctorius L..Nature and flavor: temperature, pungent.GUIXIN, Liver Channel.Effect: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.The pungent loose temperature of Flos Carthami is led to, and specially enters blood system, can blood circulation promoting and blood stasis dispelling, and stimulate the menstrual flow pulse-taking, and the mutual reinforcements between such as normal and Semen Persicae, Radix Angelicae Sinensis, Rhizoma Chuanxiong are for use.Flos Carthami has blood vessel dilating effect.Carthamus yellow can obviously extend blood plasma recalcification time, prothrombin time and clotting time." Amplification on Materia Medica addendum ": " Flos Carthami, broken stagnant blood, nourishes blood.Multiplex then removing blood stasis is few with then nourishing blood." crude extract from carthamus tinctorius L. with water has slight excited heart, increases the effect of coronary flow, have myocardial ischemia and alleviate effect, and make decreased heart rate, the amplitude that electrocardiogram S-T section is raised significantly declines, and also has anticoagulant and increases fibrinolysis activity.
Rhizoma Chuanxiong: be the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort..Nature and flavor: pungent, temperature.Return liver, gallbladder, heart channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.The pungent loose temperature of this product is led to, can top, up mountain peak, assigns the sea of blood, outer thorough fur, bypass extremity, can invigorate blood circulation and can circulation of qi promoting, and it is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.If heart arteries and veins stasis blocking, obstruction of qi in the chest and cardialgia, then normal being equal to Ramulus Cinnamomi, Radix Salviae Miltiorrhizae, is used.This product contains ligustrazine can suppress vascular smooth muscle contraction, coronary artery dilator, increase coronary flow, improve myocardial ischemia situation and Mesentery microcirculation, increase brain and LBF amount, reduce peripheral vascular resistance, can also anticoagulant, can the formation of preventing thrombosis in advance, there is good curative effect to cardiovascular and cerebrovascular disease.
Radix Salviae Miltiorrhizae: be the dry root and rhizome of dicotyledon Labiatae Labiatae salvia Radix Salviae Miltiorrhizae Salvia/miltiorrhizaBge.Nature and flavor: bitter, are slightly cold.Gui Jing: enter the heart, Liver Channel.Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind.For costa sternales hypochondriac pain, rheumatic arthralgia, lump in the abdomen lumps.Modern medicine experiment proves, Radix Salviae Miltiorrhizae also has anti-platelet aggregation, reduces the function of blood viscosity and the inside and outside blood coagulation system of adjustment, is the natural Chinese medicine that a kind of safety treats again thrombus disease reliably.
Spina Gleditsiae: be the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Nature and flavor: pungent, temperature.Return lung, Liver Channel.Effect: detumescence and apocenosis, promoting blood circulation by removing wind.Modern pharmacology is studied its decoct flat board and to be burrowed method, has inhibitory action to staphylococcus aureus and micrococcus catarrhalis.It is up that Spina Gleditsiae can draw all medicines, the kind disease controlling the part of the body cavity above the diaphragm housing the heart and lungs.
Radix Codonopsis: be the dry root of Campanulaceae Radix Codonopsis Codonopsis pilosula (Franch.) Nannf., element flower Radix Codonopsis Codonopsis pilosula Nannf.var.modesta (Nannf.) L.T.Shen or radix codonpsis tangshen Codonopsis tangshen Oliv..Nature and flavor: sweet, flat.Return spleen, lung meridian.Effect: mend strengthening spleen and lung, nourishing blood to promote the production of body fluid.For deficiency of the spleen and lung, breathe hard, cardiopalmus, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.Acid mucopolysaccharide in Radix Codonopsis has anticoagulant, can reduce blood fat and reduce blood viscosity and plasma viscosity, and has blood pressure lowering, blood fat reducing, antioxidation, defying age, improves the immunity of human body.Old myocardial infarction and cerebral thrombosis recovery phase are made moderate progress, has and purify the blood, prophylaxis of hypertension, the effect of cardiovascular and cerebrovascular disease.
Rhizoma Atractylodis Macrocephalae (parched): be the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..Nature and flavor: bitter, sweet, temperature.Return spleen, stomach warp.Effect: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, the Rhizoma Atractylodis Macrocephalae can air making-up and spleen enlivening, again can dampness diuretic, is the key medicine of the spleen strengthening and damp drying.In the sweet temperature compensation of the Rhizoma Atractylodis Macrocephalae, can air making-up and spleen enlivening, also can strengthening superficial resistance to stop perspiration, and the Radix Astragali, Radix Pseudostellariae compatibility, play the merit of spleen reinforcing lung altogether.To rule together asthenia, the weak person of overstrain.Rhizoma Atractylodis Macrocephalae antibacterial action is obvious: infusion has inhibitory action to acrothesium floccosum, star nocardia in vitro.Decoct also has inhibitory action to meningococcus.The Rhizoma Atractylodis Macrocephalae also has the function promoting hemopoietic.
Poria: be the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.Nature and flavor: sweet, light, flat.GUIXIN, lung, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Sweet the providing additional supplies of this product is oozed, and not only mends but also sharp, and effect is gentle, and property is flat and partially without cold and heat, is the key medicine of promoting diuresis to eliminate damp pathogen.Poria decoct has obvious sedation." modality ": " cure mainly Ji Rou Shun muscle of throbbing with fear cautious, dizziness agitation is controlled on side." this product is by heart-spleen boosting and tranquilizing mind.Be used for deficiency of both the heart and spleen, the irritability of insufficiency of vital energy and blood.
Radix Glycyrrhizae Preparata: be the dry root and rhizome of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza Inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza Glabra L..Radix Glycyrrhizae Preparata is that processed goods smoked by the honey of Radix Glycyrrhizae.Nature and flavor are sweet, flat.GUIXIN, lung, spleen, stomach warp.Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery." Japan hanako materia medica ": peace soul determines soul.Mend five kinds of strain and seven kinds of impairment, all be deficient, palpitation with fear, unhappy, forgetful.Logical nine orifices, sharp hundred arteries and veins, beneficial intensive culture gas, strengthening bone and muscle, separates cold and hot.
Side's solution of the present invention is: square epheday intermedia, Ramulus Cinnamomi diaphoresis cold expelling, depressed lung-energy dispersing, the expectorant of Rhizoma Zingiberis dampness, warming the lung to resolve fluid-retention, Herba Asari warming the lung to resolve fluid-retention, the therapeutic method to keep the adverse QI flowing downwards are eliminated the phlegm, Rhizoma Pinelliae drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the above five tastes are monarch drug altogether, fundamentally carry out drying dampness to eliminate phlegm, depressed lung-energy dispersing from disease, diaphoresis cold expelling, pulmonary circulation is strengthened, reduces pulmonary vascular resistance, thus alleviate the phenomenon of pulmonary hypertension.Fructus Schisandrae Chinensis supplementing QI for promoting the production of body fluid, kidney calming, the Radix Paeoniae Alba enrich blood easing the affected liver, yin fluid astringing receive antiperspirant, Rhizoma Belamcandae heat-clearing and toxic substances removing, expectorant sore-throat relieving, Semen Lepidii (Semen Descurainiae) eliminating pathogen from the lung for relieving asthma, line water detumescence, the Radix Astragali, Chinese angelica blood supplementing are invigorated blood circulation, tonifying Qi and lifting yang, above Six-element is ministerial drug altogether, assist a ruler in governing a country on the one hand monarch drug depressed lung-energy dispersing, on the other hand enrich blood invigorates blood circulation, kidney calming, pained, the tachypnea that treatment chronic pulmonary heart disease causes, cardio palmus shape, and carry out taking a tonic or nourishing food to build up one's health conditioning to the health of patient, strengthen patient's body constitution, promote that patient recovers.The lung heat clearing of Radix Rhodiolae QI invigorating, Fructus Alpiniae Oxyphyllae is nourished heart, Gecko invigorating the lung and the kidney, improving inspiration by invigorating kidney-QI Dingchuan, Lignum Aquilariae Resinatum promoting the circulation of QI to relieve pain, helping inspiration to relieve asthma, Semen Persicae, Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, nourishing blood to tranquillize the mind, Spina Gleditsiae promoting blood circulation by removing wind, strengthening spleen and lung mended by Radix Codonopsis, nourishing blood to promote the production of body fluid, Rhizoma Atractylodis Macrocephalae (parched), Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming, a few taste is adjuvant drug altogether above, other complication that relieve chronic pulmonary heart disease brings, and there is anti-inflammation, the effect of promoting blood circulation to restore menstrual flow, get through pulmonary artery, blood vessel stasis blocking near heart, that blood operation is smooth, thus reach the object for the treatment of chronic pulmonary heart disease, Radix Glycyrrhizae Preparata priming return through, coordinating the actions of various ingredients in a prescription, for making medicine.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, has effect of dampness expectorant, depressed lung-energy dispersing, nourishing blood to tranquillize the mind, supplementing QI for promoting the production of body fluid, effectively can treat chronic pulmonary heart disease.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Herba Ephedrae 3-9 part, Ramulus Cinnamomi 7-17 part, Rhizoma Zingiberis 7-17 part, Herba Asari 1-5 part, Rhizoma Pinelliae 4-14 part, Fructus Schisandrae Chinensis 5-15 part, Radix Paeoniae Alba 7-17 part, Rhizoma Belamcandae 7-17 part, Semen Lepidii (Semen Descurainiae) 4-14 part, Radix Astragali 13-23 part, Radix Angelicae Sinensis 10-20 part, Radix Rhodiolae 7-17 part, Gecko 3-9 part, Lignum Aquilariae Resinatum 1-5 part, Semen Persicae 7-17 part, Flos Carthami 4-14 part, Rhizoma Chuanxiong 7-17 part, Radix Salviae Miltiorrhizae 13-23 part, Spina Gleditsiae 10-20 part, Radix Codonopsis 10-20 part, Rhizoma Atractylodis Macrocephalae (parched) 13-23 part, Poria 7-17 part, Radix Glycyrrhizae Preparata 3-9 part.
Wherein be preferably: 6 parts, Herba Ephedrae, Ramulus Cinnamomi 12 parts, Rhizoma Zingiberis 12 parts, Herba Asari 3 parts, the Rhizoma Pinelliae 9 parts, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Belamcandae 12 parts, Semen Lepidii (Semen Descurainiae) 9 parts, the Radix Astragali 18 parts, Radix Angelicae Sinensis 15 parts, Radix Rhodiolae 12 parts, Gecko 6 parts, Lignum Aquilariae Resinatum 3 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 18 parts, Spina Gleditsiae 15 parts, Radix Codonopsis 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 18 parts, 12 parts, Poria, Radix Glycyrrhizae Preparata 6 parts.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, as pill, powder, tablet, oral liquid etc.Such as these crude drug pulverize mix homogeneously can be made powder to take after mixing it with water; Can decocting be used, obtain filtrate after filtration, add antiseptic and make oral liquid; Also directly decoction can be taken if desired.
The preferred preparation method of the present invention is decoction, and its preparation method is as follows:
Step one: by weight proportion of the present invention, first becomes medicated bag by Fructus Schisandrae Chinensis, Semen Lepidii (Semen Descurainiae) bundle, is put in water and soaks about 45 minutes, filters, for subsequent use;
Step 2: by weight proportion of the present invention, grinds to 200 mesh sieves by Gecko, Semen Persicae, Rhizoma Atractylodis Macrocephalae (parched), Poria, for subsequent use;
Step 3: by weight proportion of the present invention, by Rhizoma Zingiberis, the Radix Paeoniae Alba, Rhizoma Belamcandae, the Radix Astragali, Radix Angelicae Sinensis, Lignum Aquilariae Resinatum, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Codonopsis is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 6 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, then Herba Ephedrae is added, Herba Asari, the Rhizoma Pinelliae, Radix Rhodiolae, medicated bag in Spina Gleditsiae and step one decocts about 30 minutes, add Ramulus Cinnamomi afterwards, Flos Carthami, Radix Glycyrrhizae Preparata decocts filtration in 15 minutes, obtain filtrate, merge twice filtrate, filter, waste, add the powder in step 2, mix homogeneously, both Chinese medicine decoction of the present invention, sooner or later respectively once, decoction being taken warmly.
The effects such as medicine dampness of the present invention expectorant, depressed lung-energy dispersing, nourishing blood to tranquillize the mind, supplementing QI for promoting the production of body fluid, and it is evident in efficacy, cheap, with strong points, have no side effect, not easily recur, the mode that this Chinese medicine preparation adopts is treated and can be reduced the damage of Western medicine to patient's hepatic and renal function, fundamentally carry out conditioning health, recuperating cures the disease combines, and accelerates the improvement of the state of an illness, adds up according to clinical 196 routine patient view, to use after a course for the treatment of of medicine of the present invention total effective rate 96% after 89.8%, two courses for the treatment of of total effective rate.
Detailed description of the invention
Embodiment one, 3 parts, Herba Ephedrae, Ramulus Cinnamomi 7 parts, Rhizoma Zingiberis 7 parts, Herba Asari 1 part, the Rhizoma Pinelliae 4 parts, Fructus Schisandrae Chinensis 5 parts, the Radix Paeoniae Alba 7 parts, Rhizoma Belamcandae 7 parts, Semen Lepidii (Semen Descurainiae) 4 parts, the Radix Astragali 13 parts, Radix Angelicae Sinensis 10 parts, Radix Rhodiolae 7 parts, Gecko 3 parts, Lignum Aquilariae Resinatum 1 part, 7 parts, Semen Persicae, 4 parts, Flos Carthami, Rhizoma Chuanxiong 7 parts, Radix Salviae Miltiorrhizae 13 parts, Spina Gleditsiae 10 parts, Radix Codonopsis 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 13 parts, 7 parts, Poria, Radix Glycyrrhizae Preparata 3 parts.
Embodiment two, 6 parts, Herba Ephedrae, Ramulus Cinnamomi 12 parts, Rhizoma Zingiberis 12 parts, Herba Asari 3 parts, the Rhizoma Pinelliae 9 parts, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Belamcandae 12 parts, Semen Lepidii (Semen Descurainiae) 9 parts, the Radix Astragali 18 parts, Radix Angelicae Sinensis 15 parts, Radix Rhodiolae 12 parts, Gecko 6 parts, Lignum Aquilariae Resinatum 3 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 18 parts, Spina Gleditsiae 15 parts, Radix Codonopsis 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 18 parts, 12 parts, Poria, Radix Glycyrrhizae Preparata 6 parts.
Embodiment three, 9 parts, Herba Ephedrae, Ramulus Cinnamomi 17 parts, Rhizoma Zingiberis 17 parts, Herba Asari 5 parts, the Rhizoma Pinelliae 14 parts, Fructus Schisandrae Chinensis 15 parts, the Radix Paeoniae Alba 17 parts, Rhizoma Belamcandae 17 parts, Semen Lepidii (Semen Descurainiae) 14 parts, the Radix Astragali 23 parts, Radix Angelicae Sinensis 20 parts, Radix Rhodiolae 17 parts, Gecko 9 parts, Lignum Aquilariae Resinatum 5 parts, 17 parts, Semen Persicae, 14 parts, Flos Carthami, Rhizoma Chuanxiong 17 parts, Radix Salviae Miltiorrhizae 23 parts, Spina Gleditsiae 20 parts, Radix Codonopsis 20 parts, Rhizoma Atractylodis Macrocephalae (parched) 23 parts, 17 parts, Poria, Radix Glycyrrhizae Preparata 9 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 392 example for medical treatment.Patient is divided into observation group and matched group at random, wherein male 200 example, women 192 example, M-F 1: 04.1, max age 81 years old, minimal ages 40 years old, the course of disease time is not etc., every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, Therapeutic Method:
1, observation group is according to Medications Example two of the present invention, and preferred preparation method, weighting raw materials (daily dose), and filter and remove residue after decocting, services once, decoction being taken warmly sooner or later.It within 15 days, is a course for the treatment of.
2, matched group is according to the Chinese medicine composition for the treatment of chronic pulmonary heart disease in CN 102961699A, every day twice, within 15 days, is an observation cycle.
Three, efficacy assessment standard
1, cure: each clinical symptom disappearance of chronic pulmonary heart disease, auscultation of lung is done moist rale and is disappeared, and electrocardiogram and chest X-ray recover normal.
2, take a turn for the better: each clinical symptoms of chronic pulmonary heart disease obviously alleviates, and body constitution is progressively recovered, and electrocardiogram and chest X-ray obviously improve, edema extinction.
3, do not heal: chronic pulmonary heart disease clinical symptoms is without any improvement.
Four, observation group's result statistics
Matched group result is added up
Wherein: total effective rate=cure rate+improvement rate
Use the Comparison of therapeutic situation of two groups of patients after two courses for the treatment of
Group Number of cases Cure [n (%)] Take a turn for the better [n (%)] Do not heal [n (%)] Total effective rate (%)
Observation group 196 134(68.4) 54(27.6) 8(4) 96.0
Matched group 196 63(32) 88(45) 45(23) 77.0
Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness at treatment chronic pulmonary heart disease, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, Lee, female, 59 years old, patient's body constitution is always bad, suffers from chronic pulmonary heart disease, and with chronic obstructive pulmonary disease, cough, expectoration phenomenon is more than, gasp for breath through normal after each activity, there is the phenomenon of breathing heavily and suppressing, use is relievingd asthma and some anti-infective Drug therapys, effect is always undesirable, at all can not drug withdrawal, went to a doctor in here afterwards, adopt made decoction in the embodiment of the present invention two, after patient takes two courses for the treatment of, cough, expectoration phenomenon obviously alleviates, breathe heavily after activity and suppress phenomenon and be eased, cardiopalmus, edema of lower limbs phenomenon also disappears, for consolidate curative effect, continue to take two courses for the treatment of, patient clinical symptom disappears completely, activity freely, obvious sensation body constitution is also enhanced, the mental status also improves, follow up a case by regular visits to half a year, have no recurrence recovery from illness.
Case two, Bai, man, 64 years old, cough, breathe hard, feeling of distension and oppression over the chest, cough with asthma, time tired, sensation obviously increases the weight of, sometimes cardio palmus shape can obviously be felt, remove examination in hospital, be diagnosed as chronic pulmonary heart disease, carry out here treatment, adopt made decoction in the embodiment of the present invention two, after patient takes two courses for the treatment of, sensory symptoms obviously alleviates, breathe smooth and easy, do not cough and do not breathe heavily, cardiopalmus, phenomenon uncomfortable in chest is also eased, the mental status is improved, continue to take a course for the treatment of, patient clinical symptom disappears completely, body constitution also improves, activity freely, without other malaise symptoms, follow up a case by regular visits to half a year, have no recurrence, recovery from illness.
Case three, in certain, man, 69 years old, patient respiratory difficulty, cardiopalmus, and with puffiness of face, appetite is poor, cough with asthma is out of breath, the symptoms such as appetite difference, especially when evening, sleep quality degradation, body constitution worse and worse, be diagnosed as chronic pulmonary heart disease, take some medicines such as relievining asthma, effect is always not obvious, went to a doctor in here afterwards, adopt made decoction in the embodiment of the present invention two, after taking three courses for the treatment of, symptom sensation obviously alleviates, sensation of oppression over the chest with shortness of breath phenomenon is also eased, nocturnal cough obviously alleviates, sleep quality is improved, for consolidate curative effect, patient continues to take two courses for the treatment of, patient feels that breathing is smooth and easy, without sense of discomfort, cardiopalmus, phenomenon uncomfortable in chest disappears completely, other clinical symptoms also disappear, follow up a case by regular visits to half a year, have no recurrence, recovery from illness.

Claims (4)

1. treat the Chinese medicine composition of chronic pulmonary heart disease for one kind, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Herba Ephedrae 3-9 part, Ramulus Cinnamomi 7-17 part, Rhizoma Zingiberis 7-17 part, Herba Asari 1-5 part, Rhizoma Pinelliae 4-14 part, Fructus Schisandrae Chinensis 5-15 part, Radix Paeoniae Alba 7-17 part, Rhizoma Belamcandae 7-17 part, Semen Lepidii (Semen Descurainiae) 4-14 part, Radix Astragali 13-23 part, Radix Angelicae Sinensis 10-20 part, Radix Rhodiolae 7-17 part, Gecko 3-9 part, Lignum Aquilariae Resinatum 1-5 part, Semen Persicae 7-17 part, Flos Carthami 4-14 part, Rhizoma Chuanxiong 7-17 part, Radix Salviae Miltiorrhizae 13-23 part, Spina Gleditsiae 10-20 part, Radix Codonopsis 10-20 part, Rhizoma Atractylodis Macrocephalae (parched) 13-23 part, Poria 7-17 part, Radix Glycyrrhizae Preparata 3-9 part.
2. the Chinese medicine composition of the treatment chronic pulmonary heart disease according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: 6 parts, Herba Ephedrae, Ramulus Cinnamomi 12 parts, Rhizoma Zingiberis 12 parts, Herba Asari 3 parts, the Rhizoma Pinelliae 9 parts, Fructus Schisandrae Chinensis 10 parts, the Radix Paeoniae Alba 12 parts, Rhizoma Belamcandae 12 parts, Semen Lepidii (Semen Descurainiae) 9 parts, the Radix Astragali 18 parts, Radix Angelicae Sinensis 15 parts, Radix Rhodiolae 12 parts, Gecko 6 parts, Lignum Aquilariae Resinatum 3 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Rhizoma Chuanxiong 12 parts, Radix Salviae Miltiorrhizae 18 parts, Spina Gleditsiae 15 parts, Radix Codonopsis 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 18 parts, 12 parts, Poria, Radix Glycyrrhizae Preparata 6 parts.
3. the Chinese medicine preparation for the treatment of chronic pulmonary heart disease according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is decoction.
4. treat a preparation method for the Chinese medicine preparation of chronic pulmonary heart disease, it is characterized in that, preparation method is as follows: step one: by weight proportion of the present invention, first Fructus Schisandrae Chinensis, Semen Lepidii (Semen Descurainiae) bundle are become medicated bag, be put in water and soak about 45 minutes, filter, for subsequent use, step 2: by weight proportion of the present invention, grinds to 200 mesh sieves by Gecko, Semen Persicae, Rhizoma Atractylodis Macrocephalae (parched), Poria, for subsequent use, step 3: by weight proportion of the present invention, by Rhizoma Zingiberis, the Radix Paeoniae Alba, Rhizoma Belamcandae, the Radix Astragali, Radix Angelicae Sinensis, Lignum Aquilariae Resinatum, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, Radix Codonopsis is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 6 centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, then Herba Ephedrae is added, Herba Asari, the Rhizoma Pinelliae, Radix Rhodiolae, medicated bag in Spina Gleditsiae and step one decocts about 30 minutes, add Ramulus Cinnamomi afterwards, Flos Carthami, Radix Glycyrrhizae Preparata decocts filtration in 15 minutes, obtain filtrate, merge twice filtrate, filter, waste, add the powder in step 2, mix homogeneously, both Chinese medicine decoction of the present invention, sooner or later respectively once, decoction being taken warmly.
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Publication number Priority date Publication date Assignee Title
CN111514220A (en) * 2020-05-15 2020-08-11 陶渝生 Traditional Chinese medicine composition for treating coronary atherosclerotic heart disease and preparation method thereof

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CN1259360A (en) * 1998-10-29 2000-07-12 何天有 Medicine for treating pulmonary hart diseases

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514220A (en) * 2020-05-15 2020-08-11 陶渝生 Traditional Chinese medicine composition for treating coronary atherosclerotic heart disease and preparation method thereof

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