CN103611003A - Traditional Chinese medicine composition for improving somatic functions of patients with lung cancer and preparation method thereof - Google Patents
Traditional Chinese medicine composition for improving somatic functions of patients with lung cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for improving somatic functions of patients with lung cancer, The invention is characterized in that the composition is prepared from the following medicinal materials in parts by weight: 6-12 parts of dangshen, 6-12 parts of radix astragali, 6-12 parts of rhizoma atractylodis macrocephalae, 12-18 parts of tuckahoe, 12-18 parts of Polyporus umbellatus, 12-18 parts of Coix Semen Coicis, 5-13 parts of dried orange peel, 26-35 parts of herba oldenlandiae, 26-35 parts of herba houttuyniae and 26-35 parts of folium cycas. The preparation method comprises the following steps: weighing the medicinal materials, putting into a container, adding 8 times of water, decocting for 1.5 hours, and filtering; adding 6 times of water into the filter residue, decocting for 1 hour, and filtering; and merging the filtrates, concentrating, drying and encapsulating. The clinical experiment proves that the proper medicinal materials and proportion thereof are selected to achieve the obvious effect of improving the somatic functions of patients with lung cancer, and the composition has the advantages of high safety and no toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of for improving Chinese medicine composition of patients with lung cancer physical function and preparation method thereof.
Background technology
Pulmonary carcinoma is that M & M growth is the fastest, and population health and life are threatened to one of maximum malignant tumor.Over nearly 50 years, many countries all report that the M & M of pulmonary carcinoma all obviously increases, and male lung cancer M & M all accounts for first of all malignant tumor, and women's sickness rate accounts for second, and mortality rate accounts for second.The clinical manifestation more complicated of pulmonary carcinoma, the morning and evening of the having or not of sings and symptoms, weight and appearance, depend on tumor happening part, histological type, have or not and shift and have or not complication, and the difference of reaction degree and toleration.Pulmonary carcinoma early symptom is often slighter, even can be without any discomfort.Central type carcinoma of lung symptom occurs early and is heavy, in peripheral type carcinoma of lung symptom appearance evening and lighter, even asymptomatic, while being everlasting health check-up, is found.
Chinese medicine formula about treatment pulmonary carcinoma has a lot.As Chinese patent CN01118917.7 discloses a kind of Chinese medicine preparation for the treatment of pulmonary carcinoma, according to monarch, minister, help, make principles of formulating prescriptions compatibility.Monarch drug is Cordyceps; Ministerial drug comprises Radix Adenophorae, Radix Glehniae, Bulbus Lilii; Adjuvant drug comprises Fructus Polygoni Orientalis, Herba Taraxaci, Herba Hedyotidis Diffusae, Carapax Trionycis, Radix Notoginseng; Making medicine is Fructus Trichosanthis.The present invention is without toxicity, has righting, tumor suppression, eliminates the phlegm, antitussive and antifatigue effect.Eliminating evil experiment has obvious inhibition effectiveness to Lewis lung cancer and hepatocarcinoma Hep solid tumor, and S180 sarcoma and ehrlich carcinoma are had to tumor suppression and the effect of extending life survival rate.But in practical application, the actual therapeutic effect of related Chinese medicinal composition is not very good, and exists in varying degrees certain toxic and side effects.
Summary of the invention
The present invention aims to provide a kind of for improving Chinese medicine composition of patients with lung cancer physical function and preparation method thereof, by selecting suitable medical material and proportioning thereof, reaches effective remarkable efficacy of improving patients with lung cancer physical function, and safe without toxic side effect.
In order to achieve the above object, the present invention is by the following technical solutions: a kind of for improving the Chinese medicine composition of patients with lung cancer physical function, by the medical material of following weight proportion, be prepared from: 6～12 parts of Radix Codonopsis, 6～12 parts of the Radixs Astragali, 6～12 parts of the Rhizoma Atractylodis Macrocephalaes, 12～18 parts, Poria, 12～18 parts of Polyporus, 12～18 parts of raw Semen Coiciss, 5～13 parts of Pericarpium Citri Reticulataes, 26～35 parts of Herba Hedyotidis Diffusaes, 26～35 parts of Herba Houttuyniae, 26～35 parts of Folium cordylines fruticosaes.
As preferably, by the medical material of following weight proportion, be prepared from: 7～11 parts of Radix Codonopsis, 7～11 parts of the Radixs Astragali, 7～11 parts of the Rhizoma Atractylodis Macrocephalaes, 13～17 parts, Poria, 13～17 parts of Polyporus, 13～17 parts of raw Semen Coiciss, 6～12 parts of Pericarpium Citri Reticulataes, 28～33 parts of Herba Hedyotidis Diffusaes, 26～31 parts of Herba Houttuyniae, 27～32 parts of Folium cordylines fruticosaes.
As preferably, by the medical material of following weight proportion, be prepared from: 8～10 parts of Radix Codonopsis, 8～10 parts of the Radixs Astragali, 8～10 parts of the Rhizoma Atractylodis Macrocephalaes, 14～16 parts, Poria, 14～16 parts of Polyporus, 14～16 parts of raw Semen Coiciss, 8～10 parts of Pericarpium Citri Reticulataes, 30～32 parts of Herba Hedyotidis Diffusaes, 28～30 parts of Herba Houttuyniae, 28～30 parts of Folium cordylines fruticosaes.
As preferably, by the medical material of following weight proportion, be prepared from: 9 parts of Radix Codonopsis, 10 parts of the Radixs Astragali, 11 parts of the Rhizoma Atractylodis Macrocephalaes, 14 parts, Poria, 15 parts of Polyporus, 16 parts of raw Semen Coiciss, 10 parts of Pericarpium Citri Reticulataes, 32 parts of Herba Hedyotidis Diffusaes, 30 parts of Herba Houttuyniae, 28 parts of Folium cordylines fruticosaes.
As preferably, by the medical material of following weight proportion, be prepared from: 9 parts of Radix Codonopsis, 9 parts of the Radixs Astragali, 9 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts, Poria, 15 parts of Polyporus, 15 parts of raw Semen Coiciss, 9 parts of Pericarpium Citri Reticulataes, 30 parts of Herba Hedyotidis Diffusaes, 30 parts of Herba Houttuyniae, 30 parts of Folium cordylines fruticosaes.
A kind of for improving the preparation method of the Chinese medicine composition of patients with lung cancer physical function, comprise the steps: to take Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Polyporus, raw Semen Coicis, Pericarpium Citri Reticulatae, Herba Hedyotidis Diffusae, Herba Houttuyniae, Folium cordylines fruticosae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
As preferably, comprise the steps: to take Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Polyporus, raw Semen Coicis, Pericarpium Citri Reticulatae, Herba Hedyotidis Diffusae, Herba Houttuyniae, Folium cordylines fruticosae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, according to this area common process, granulate.
As preferably, comprise the steps: to take Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Polyporus, raw Semen Coicis, Pericarpium Citri Reticulatae, Herba Hedyotidis Diffusae, Herba Houttuyniae, Folium cordylines fruticosae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Radix Codonopsis [function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
The Radix Astragali [function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
The Rhizoma Atractylodis Macrocephalae [function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Poria [function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Polyporus [function cures mainly] promoting diuresis to eliminate damp pathogen.For dysuria, edema, has loose bowels, stranguria with turbid discharge, leukorrhagia.
Raw Semen Coicis [function cures mainly] promoting diuresis to eliminate damp pathogen, inducing diuresis to remove edema, eliminating damp-heat, invigorating spleen to remove dampness, alleviation contracture, removing pus and relieving carbuncle.
Pericarpium Citri Reticulatae [function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Herba Hedyotidis Diffusae [function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis), furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria.
Herba Houttuyniae [function cures mainly] heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, inducing diuresis for treating stranguria syndrome.For lung abscess vomiting pus, expectorant dyspnea of heat type is coughed, hematodiarrhoea, pyretic stranguria, carbuncle sore tumefacting virus.
Folium cordylines fruticosae [function cures mainly] heat clearing away, hemostasis, dissipating blood stasis.Control dysentery, spit blood, have blood in stool, stomachache, hematuria, menorrhagia, treating swelling and pain by traumatic injury.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
Clinical patient's case 148 examples of suffering from pulmonary carcinoma of accepting for medical treatment, the Chinese medicinal formulae that adopts embodiment 1 to prepare, every day is sooner or later respectively once.Therapeutic evaluation: cure: transference cure; Effective: symptom alleviates, physical function obviously improves; Invalid: symptom does not disappear, without obviously changing.
Therapeutic outcome: effective totally 112 examples, effective percentage is followed up a case by regular visits to after the month up to 75.5%, 2-3 again, and physical function further improves.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Embodiment 1
Take: 9 grams of Radix Codonopsis, 9 grams of the Radixs Astragali, 9 grams of the Rhizoma Atractylodis Macrocephalaes, 15 grams, Poria, 15 grams of Polyporus, 15 grams of raw Semen Coiciss, 9 grams of Pericarpium Citri Reticulataes, 30 grams of Herba Hedyotidis Diffusaes, 30 grams of Herba Houttuyniae, 30 grams of Folium cordylines fruticosaes, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of pulmonary carcinoma.Every day sooner or later respectively once.
Embodiment 2
Take: 6 grams of Radix Codonopsis, 6 grams of the Radixs Astragali, 6 grams of the Rhizoma Atractylodis Macrocephalaes, 12 grams, Poria, 12 grams of Polyporus, 12 grams of raw Semen Coiciss, 5 grams of Pericarpium Citri Reticulataes, 26 grams of Herba Hedyotidis Diffusaes, 26 grams of Herba Houttuyniae, 26 grams of Folium cordylines fruticosaes, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Filtering residue adds 2 times of water gagings, decocts 1 hour, filters; Merge three times filtrate, concentrated.
Be used for the treatment of pulmonary carcinoma.Every day sooner or later respectively once.
Embodiment 3
Take: 12 grams of Radix Codonopsis, 12 grams of the Radixs Astragali, 12 grams of the Rhizoma Atractylodis Macrocephalaes, 18 grams, Poria, 18 grams of Polyporus, 18 grams of raw Semen Coiciss, 13 grams of Pericarpium Citri Reticulataes, 35 grams of Herba Hedyotidis Diffusaes, 35 grams of Herba Houttuyniae, 35 grams of Folium cordylines fruticosaes, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merge filtrate twice, concentrated.
Be used for the treatment of pulmonary carcinoma.Every day sooner or later respectively once.
Embodiment 4
Take: 9 grams of Radix Codonopsis, 10 grams of the Radixs Astragali, 11 grams of the Rhizoma Atractylodis Macrocephalaes, 14 grams, Poria, 15 grams of Polyporus, 16 grams of raw Semen Coiciss, 10 grams of Pericarpium Citri Reticulataes, 32 grams of Herba Hedyotidis Diffusaes, 30 grams of Herba Houttuyniae, 28 grams of Folium cordylines fruticosaes, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Filtering residue adds 2 times of water gagings, decocts 1 hour, filters; Merge three times filtrate, concentrated.
Be used for the treatment of pulmonary carcinoma.Every day sooner or later respectively once.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give all embodiments exhaustive.Every still row in protection scope of the present invention of apparent variation that technical scheme of the present invention extends out or change that belong to.
Claims (8)
1. one kind for improving the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, by the medical material of following weight proportion, be prepared from: 6～12 parts of Radix Codonopsis, 6～12 parts of the Radixs Astragali, 6～12 parts of the Rhizoma Atractylodis Macrocephalaes, 12～18 parts, Poria, 12～18 parts of Polyporus, 12～18 parts of raw Semen Coiciss, 5～13 parts of Pericarpium Citri Reticulataes, 26～35 parts of Herba Hedyotidis Diffusaes, 26～35 parts of Herba Houttuyniae, 26～35 parts of Folium cordylines fruticosaes.
2. according to claim 1 a kind of for improving the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, by the medical material of following weight proportion, be prepared from: 7～11 parts of Radix Codonopsis, 7～11 parts of the Radixs Astragali, 7～11 parts of the Rhizoma Atractylodis Macrocephalaes, 13～17 parts, Poria, 13～17 parts of Polyporus, 13～17 parts of raw Semen Coiciss, 6～12 parts of Pericarpium Citri Reticulataes, 28～33 parts of Herba Hedyotidis Diffusaes, 26～31 parts of Herba Houttuyniae, 27～32 parts of Folium cordylines fruticosaes.
3. according to claim 1 a kind of for improving the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, by the medical material of following weight proportion, be prepared from: 8～10 parts of Radix Codonopsis, 8～10 parts of the Radixs Astragali, 8～10 parts of the Rhizoma Atractylodis Macrocephalaes, 14～16 parts, Poria, 14～16 parts of Polyporus, 14～16 parts of raw Semen Coiciss, 8～10 parts of Pericarpium Citri Reticulataes, 30～32 parts of Herba Hedyotidis Diffusaes, 28～30 parts of Herba Houttuyniae, 28～30 parts of Folium cordylines fruticosaes.
4. according to claim 1 a kind of for improving the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, by the medical material of following weight proportion, be prepared from: 9 parts of Radix Codonopsis, 10 parts of the Radixs Astragali, 11 parts of the Rhizoma Atractylodis Macrocephalaes, 14 parts, Poria, 15 parts of Polyporus, 16 parts of raw Semen Coiciss, 10 parts of Pericarpium Citri Reticulataes, 32 parts of Herba Hedyotidis Diffusaes, 30 parts of Herba Houttuyniae, 28 parts of Folium cordylines fruticosaes.
5. according to claim 1 a kind of for improving the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, by the medical material of following weight proportion, be prepared from: 9 parts of Radix Codonopsis, 9 parts of the Radixs Astragali, 9 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts, Poria, 15 parts of Polyporus, 15 parts of raw Semen Coiciss, 9 parts of Pericarpium Citri Reticulataes, 30 parts of Herba Hedyotidis Diffusaes, 30 parts of Herba Houttuyniae, 30 parts of Folium cordylines fruticosaes.
6. one kind for improving the preparation method of the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, comprise the steps: to take Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Polyporus, raw Semen Coicis, Pericarpium Citri Reticulatae, Herba Hedyotidis Diffusae, Herba Houttuyniae, Folium cordylines fruticosae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell.
7. according to claim 6 a kind of for improving the preparation method of the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, comprise the steps: to take Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Polyporus, raw Semen Coicis, Pericarpium Citri Reticulatae, Herba Hedyotidis Diffusae, Herba Houttuyniae, Folium cordylines fruticosae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, dry, then add appropriate dextrin and correctives, according to this area common process, granulate.
8. according to claim 6 a kind of for improving the preparation method of the Chinese medicine composition of patients with lung cancer physical function, it is characterized in that, comprise the steps: to take Radix Codonopsis, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Poria, Polyporus, raw Semen Coicis, Pericarpium Citri Reticulatae, Herba Hedyotidis Diffusae, Herba Houttuyniae, Folium cordylines fruticosae, insert in container, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, concentrated, dry, pulverize.
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| CN104147450A (en) * | 2014-09-08 | 2014-11-19 | 成都市飞龙水处理技术研究所 | Orally-taken medicine for treating lung cancer and preparation method thereof |
| CN104306807A (en) * | 2014-11-18 | 2015-01-28 | 广东省中医院 | Compound preparation for treating advanced lung cancer and preparing method thereof |
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Application publication date: 20140305 |