CN105497267A - Traditional Chinese medicine composition for treating extreme noxious heat type infantile jaundice - Google Patents

Traditional Chinese medicine composition for treating extreme noxious heat type infantile jaundice Download PDF

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CN105497267A
CN105497267A CN201610047173.8A CN201610047173A CN105497267A CN 105497267 A CN105497267 A CN 105497267A CN 201610047173 A CN201610047173 A CN 201610047173A CN 105497267 A CN105497267 A CN 105497267A
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柏跃龙
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree

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Abstract

Provided is a traditional Chinese medicine composition for treating extreme noxious heat type infantile jaundice. The traditional Chinese medicine composition is prepared from roots of slenderstalk mahonia, kazinoki papermulberry branchlet and leaves, Japanese snakegourd roots, herb of American maidenhair, all-grass of matsumura leafflower, herba lysimachiae, radix scutellariae, roots of Yunnan supplejack, radix scrophulariae and lysimachia clethroides duby. The traditional Chinese medicine composition can be used for treating the extreme noxious heat type infantile jaundice in clinic.

Description

A kind of Chinese medicine composition for the treatment of extreme noxious heat infantile jaundice
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly relate to a kind of Chinese medicine composition for the treatment of extreme noxious heat infantile jaundice.
Background technology
Infantile jaundice refers to that the abnormal blood mesobilirubin level that causes of bilirubin metabolism raises and occurs the clinical symptoms of skin, sclera and mucosa xanthochromia.Clinical common pattern of syndrome has: excessive noxious heat, cold coagulation sun decline, dampness-heat in the liver and gallbladder, the spleen and stomach being stranded by dampness.The clinical symptoms main manifestations of extreme noxious heat infantile jaundice is: fall ill hurried, jaundice is deepened rapidly, yellow skin as gold, with the hot excessive thirst of height, unconsciousness and delirium, or see epistaxis, have blood in stool, skin ecchymosis, deep red tongue, yellow fur and dry, stringy and rolling pulse number.The comprehensive remedy measures such as infantile jaundice many employings combination of Chinese and Western medicine and phototherapy clinically.Long-term practice through inventor draws, treatment by Chinese herbs extreme noxious heat infantile jaundice has better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment extreme noxious heat infantile jaundice of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizing the property of medicine of Chinese medicine uniqueness, adopting Radix Berberidis anhweiensis, Folium et Cacumen Broussonetiae Kazinoki, Radix Trichosanthis Cucumeroidis, Herba adianti pedati, Herba Phyllanthi matsumuraes, Herba Lysimachiae, Radix Scutellariae, Radix Berchemiae Yunnanensis, Radix Scrophulariae, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention to be made up of following raw material medicaments: Radix Berberidis anhweiensis 30-50 part, Folium et Cacumen Broussonetiae Kazinoki 20-40 part, Radix Trichosanthis Cucumeroidis 20-40 part, Herba adianti pedati 20-40 part, Herba Phyllanthi matsumuraes 15-25 part, Herba Lysimachiae 15-25 part, Radix Scutellariae 15-25 part, Radix Berchemiae Yunnanensis 9-15 part, Radix Scrophulariae 9-15 part, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 9-15 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: Radix Berberidis anhweiensis 40 parts, Folium et Cacumen Broussonetiae Kazinoki 30 parts, Radix Trichosanthis Cucumeroidis 30 parts, 30 parts, Herba adianti pedati, Herba Phyllanthi matsumuraes 20 parts, Herba Lysimachiae 20 parts, Radix Scutellariae 20 parts, Radix Berchemiae Yunnanensis 12 parts, Radix Scrophulariae 12 parts, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 12 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Radix Berberidis anhweiensis: bitter, cold.Heat clearing and damp drying, eliminating fire and detoxication.Cure mainly jaundice due to damp-heat, diarrhoea, dysentery, conjunctival congestion and swelling pain, pathopyretic ulcer, beriberoid pyretic arthralgia.
Folium et Cacumen Broussonetiae Kazinoki: sweet, light is flat.Expelling wind and removing dampness, promoting blood circulation and stopping pain.Cure mainly rheumatic arthralgia, have loose bowels, dysentery, jaundice, edema, carbuncle furuncle, traumatic injury.
Radix Trichosanthis Cucumeroidis: bitter, cold.Return large intestine, stomach warp.Purge heat and promote the production of body fluid, dissipating blood stasis for subsidence of swelling.Cure mainly calentura excessive thirst, jaundice, constipation with heat retention, dysuria, amenorrhea, agalactia , mass in the abdomen, carbuncle.
Herba adianti pedati: bitter, is slightly cold.Return lung, liver, urinary bladder channel.Heat-clearing and toxic substances removing, relieving stranguria by diuresis.Cure mainly cough due to lung-heat, dysentery, jaundice, urine leaching is puckery, carbuncle, scrofula, scalds.
Herba Phyllanthi matsumuraes: bitter, cold.Clearing away heat-damp and promoting diuresis, liver heat removing and eyesight improving.Cure mainly jaundice, dysentery, have loose bowels, edema, gonorrhea, infantile malnutrition, conjunctival congestion and swelling pain, hemorrhoid, venom.
Herba Lysimachiae: sweet, micro-hardship is cool.Return liver, gallbladder, kidney, urinary bladder channel.Heat clearing away, dampness removing, treating stranguria, calculus, removing toxic substances.Cure mainly jaundice due to damp-heat, pyretic stranguria, oedema due to nephritis, liver, gallbladder and urinary system calculus, pyretic toxicity carbuncle, venom.
Radix Scutellariae: bitter, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Clearing away heat-fire, dampness is detoxified, hemostasis, antiabortive.Cure mainly cough due to lung-heat, calentura unconsciousness due to high fever, liver-fire is had a headache, and conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria, tells nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle.
Radix Berchemiae Yunnanensis: bitter, micro-, cool.Heat clearing away, dampness removing, removing toxic substances.Cure mainly pyretic stranguria, jaundice, dysentery, leukorrhagia, traumatic injury.
Radix Scrophulariae: sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Removing heat from blood, nourishing YIN to lower pathogenic fire, removing toxic substances.Cure mainly warm febrile disease to join the army blood, fever of the body, excessive thirst, crimson tongue, send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, scrofula sucutaneous nodule, skin sore.
Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis): bitter, pungent is flat.Clearing away heat-damp and promoting diuresis, promoting blood circulation to remove blood stasis, removing toxicity for eliminating carbuncles.Cure mainly edema, pyretic stranguria, jaundice, dysentery, beriberoid pyretic arthralgia, leukorrhagia, amenorrhea, traumatic injury, fracture, traumatic hemorrhage, acute mastitis, furuncle, venom.
The traditional Chinese medical science is thought, the many heresies because of diseases caused by exogenous pathogenic factor pyretic toxicity of extreme noxious heat infantile jaundice, and cause excessive noxious heat, suffocating of liver and gall is unfavorable in addition, and bile is excessive, invades skin table, bet bladder, therefore sees that body, order, urine are all yellow.Radix Berberidis anhweiensis heat clearing and damp drying, eliminating fire and detoxication in the present invention are monarch drug; Folium et Cacumen Broussonetiae Kazinoki expelling wind and removing dampness, promoting blood circulation and stopping pain, Radix Trichosanthis Cucumeroidis purge heat promote the production of body fluid, dissipating blood stasis for subsidence of swelling, Herba adianti pedati heat-clearing and toxic substances removing, relieving stranguria by diuresis are ministerial drug; Herba Phyllanthi matsumuraes clearing away heat-damp and promoting diuresis, liver heat removing and eyesight improving, Herba Lysimachiae clearing away heat-damp and promoting diuresis, Radix Scutellariae clearing away heat-fire, dampness are detoxified, and Radix Berchemiae Yunnanensis clearing away heat-damp and promoting diuresis detoxifies, Radix Scrophulariae nourishing YIN to lower pathogenic fire, removing toxic substances, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) clearing away heat-damp and promoting diuresis, promoting blood circulation to remove blood stasis.Find through clinical practice, to extreme noxious heat infantile jaundice, there is unique curative effect, all medicines play altogether heat clearing and damp drying, eliminating fire and detoxication, expelling wind and removing dampness, purge heat promote the production of body fluid, the removing toxic substances of heat-clearing and toxic substances removing, liver heat removing and eyesight improving, clearing away heat-fire, dampness, nourishing YIN to lower pathogenic fire, promoting blood circulation to remove blood stasis effect, reach the object for the treatment of extreme noxious heat infantile jaundice.
Chinese medicine composition of the present invention was in 2008 to 2012 the routine patients of clinical observation extreme noxious heat infantile jaundice 128, and clinical report is as follows:
1, physical data
In 128 routine patients, girl 63 example, boy 65 example, at minimum 4 months of age, maximum 6 years old, the course of disease was many at 2 days to 15 days, 2.5 years old mean age.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
icteric sclera, skin are yellow, yellowish urine, based on icteric sclera;
from the beginning of there being fever with aversion to cold, indigestion and loss of appetitely detest oil, nausea and vomiting, spiritlessness and weakness, or stool color is thin out;
there is eating and drinking without temperance, the medical histories such as hepatitis contact or applied chemistry goods medicine;
liver, spleen or gollbladder dilation, with tenderness or tenderness.
And have following symptom: fall ill hurried, jaundice is deepened rapidly, yellow skin as gold, with the hot excessive thirst of height, unconsciousness and delirium, or see epistaxis, have blood in stool, skin ecchymosis, deep red tongue, yellow fur and dry, stringy and rolling pulse number.
3, Therapeutic Method:
3.1 prescriptions: Radix Berberidis anhweiensis 40g, Folium et Cacumen Broussonetiae Kazinoki 30g, Radix Trichosanthis Cucumeroidis 30g, Herba adianti pedati 30g, Herba Phyllanthi matsumuraes 20g, Herba Lysimachiae 20g, Radix Scutellariae 20g, Radix Berchemiae Yunnanensis 12g, Radix Scrophulariae 12g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 12g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 3 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 specify with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Cure: jaundice disappears, other transference cures, and lab index is normal;
Take a turn for the better: jaundice and other symptoms alleviate, bilirubin is normal or reduce, and other lab index take a turn for the better;
Do not heal: jaundice is not moved back or deepened, other symptoms and lab index are without improvement.
4.2 results: in 128 routine patients, cure 111 examples (86.7%), 14 examples that take a turn for the better (10.9%), and do not heal 3 examples (2.4%), and total effective rate is 97.6%.
5, model case
5.1 Liu, man, 1 years old 3 months, binocular and whole skin jaundice, yellow skin as gold, nausea and vomiting, high hot excessive thirst, deep red tongue, yellow fur and dry, stringy and rolling pulse number.Be diagnosed as extreme noxious heat infantile jaundice.Take medicine of the present invention, treat 1 course for the treatment of, binocular and whole skin xanthochromia obviously disappear, and continue to take 2 courses for the treatment of, all diseases all disappear, recovery from illness, follow up a case by regular visits to without recurrence after 1 year.
5.2 Zhangs, female, 2 years old 5 months, binocular and whole skin jaundice, oliguria yellow skin was as gold, and irritated with high heat, skin has ecchymosis, deep red tongue, yellow fur and dry, stringy and rolling pulse number.Be diagnosed as extreme noxious heat infantile jaundice.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, binocular and whole skin xanthochromia obviously go down, and body temperature is normal, and spirit takes a turn for the better, and urine volume polychrome is yellowish, continues to take 2 courses for the treatment of, and all diseases all disappear, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
5.3 Liu, man, 3 years old, skin and binocular xanthochromia, large dry stool, urine was deep yellow, whole skin and sclera severe xanthochromia, with the hot excessive thirst of height, listless, deep red tongue, yellow fur and dry, stringy and rolling pulse number.Be diagnosed as extreme noxious heat infantile jaundice.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, binocular and whole skin xanthochromia obviously go down, and continue to take 2 courses for the treatment of, all diseases all disappear, recovery from illness, follow up a case by regular visits to without recurrence after 1 year.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, treating a Chinese medicine composition for extreme noxious heat infantile jaundice, is be made up of Radix Berberidis anhweiensis 30g, Folium et Cacumen Broussonetiae Kazinoki 20g, Radix Trichosanthis Cucumeroidis 20g, Herba adianti pedati 20g, Herba Phyllanthi matsumuraes 15g, Herba Lysimachiae 15g, Radix Scutellariae 15g, Radix Berchemiae Yunnanensis 9g, Radix Scrophulariae 9g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 9g.
Embodiment 2, treating a Chinese medicine composition for extreme noxious heat infantile jaundice, is be made up of Radix Berberidis anhweiensis 40g, Folium et Cacumen Broussonetiae Kazinoki 30g, Radix Trichosanthis Cucumeroidis 30g, Herba adianti pedati 30g, Herba Phyllanthi matsumuraes 20g, Herba Lysimachiae 20g, Radix Scutellariae 20g, Radix Berchemiae Yunnanensis 12g, Radix Scrophulariae 12g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 12g.
Embodiment 3, treating a Chinese medicine composition for extreme noxious heat infantile jaundice, is be made up of Radix Berberidis anhweiensis 50g, Folium et Cacumen Broussonetiae Kazinoki 40g, Radix Trichosanthis Cucumeroidis 40g, Herba adianti pedati 40g, Herba Phyllanthi matsumuraes 25g, Herba Lysimachiae 25g, Radix Scutellariae 25g, Radix Berchemiae Yunnanensis 15g, Radix Scrophulariae 15g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 15g.

Claims (2)

1. treat the Chinese medicine composition of extreme noxious heat infantile jaundice for one kind, it is characterized in that, it is made up of following raw material medicaments: Radix Berberidis anhweiensis 30-50 part, Folium et Cacumen Broussonetiae Kazinoki 20-40 part, Radix Trichosanthis Cucumeroidis 20-40 part, Herba adianti pedati 20-40 part, Herba Phyllanthi matsumuraes 15-25 part, Herba Lysimachiae 15-25 part, Radix Scutellariae 15-25 part, Radix Berchemiae Yunnanensis 9-15 part, Radix Scrophulariae 9-15 part, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 9-15 part.
2. Chinese medicine composition according to claim 1, it is characterized in that, it is made up of following raw material medicaments: Radix Berberidis anhweiensis 40 parts, Folium et Cacumen Broussonetiae Kazinoki 30 parts, Radix Trichosanthis Cucumeroidis 30 parts, 30 parts, Herba adianti pedati, Herba Phyllanthi matsumuraes 20 parts, Herba Lysimachiae 20 parts, Radix Scutellariae 20 parts, Radix Berchemiae Yunnanensis 12 parts, Radix Scrophulariae 12 parts, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 12 parts.
CN201610047173.8A 2016-01-25 2016-01-25 Traditional Chinese medicine composition for treating extreme noxious heat type infantile jaundice Withdrawn CN105497267A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104922218A (en) * 2015-07-01 2015-09-23 臧海阳 Traditional Chinese medicine composition for treating exuberant heat toxin type of infantile jaundice

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103495060A (en) * 2013-09-23 2014-01-08 马立明 Chinese medicine composition for treating infantile jaundice

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103495060A (en) * 2013-09-23 2014-01-08 马立明 Chinese medicine composition for treating infantile jaundice

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104922218A (en) * 2015-07-01 2015-09-23 臧海阳 Traditional Chinese medicine composition for treating exuberant heat toxin type of infantile jaundice

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Application publication date: 20160420