CN105535149A - Traditional Chinese medicine composition for treating pediatric jaundice with liver and gallbladder wetness-heat syndrome - Google Patents
Traditional Chinese medicine composition for treating pediatric jaundice with liver and gallbladder wetness-heat syndrome Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
Abstract
The invention relates to a traditional Chinese medicine composition for treating pediatric jaundice with the liver and gallbladder wetness-heat syndrome. The traditional Chinese medicine composition is prepared from matsumura leafflower herb, rhizoma polygoni cuspidate, kazinoki papermulberry branchlets and leaves, american maidenhair fern, whole grass of cerastium viscosum L., herba artemisiae scopariae, mahonia ganpinensis fedde, semi-pinnated brake herb, Japanese snakegourd roots and roots of Yunnan supplejack. The traditional Chinese medicine composition can be clinically used for treating pediatric jaundice with the liver and gallbladder wetness-heat syndrome.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly relate to a kind of Chinese medicine composition for the treatment of liver gallbladder damp-heat type infantile jaundice.
Background technology
Infantile jaundice refers to that the abnormal blood mesobilirubin level that causes of bilirubin metabolism raises and occurs the clinical symptoms of skin, sclera and mucosa xanthochromia.Clinical common pattern of syndrome has: dampness-heat in the liver and gallbladder, the spleen and stomach being stranded by dampness, excessive noxious heat, cold coagulation sun decline.The clinical symptoms main manifestations of liver gallbladder damp-heat type infantile jaundice is: yellow skin and eye, yellow distinct, generates heat thirsty, in the heart regretful Nang, xerostomia and bitter, tending to vomit of feeling sick, abdominal distention hypochondriac pain, constipation or be canescence, oliguria with yellow urine, red tongue, yellow and greasy fur, wiry and frequent pulse.The comprehensive remedy measures such as infantile jaundice many employings combination of Chinese and Western medicine and phototherapy clinically.Long-term practice through inventor draws, treatment by Chinese herbs liver gallbladder damp-heat type infantile jaundice has better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment liver gallbladder damp-heat type infantile jaundice of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizing the property of medicine of Chinese medicine uniqueness, adopting Herba Phyllanthi matsumuraes, Rhizoma Polygoni Cuspidati, Folium et Cacumen Broussonetiae Kazinoki, Herba adianti pedati, Herba Cerastii glomerati, Herba Artemisiae Scopariae, Radix Berberidis anhweiensis, Herba Pteridis Semipinnatae, Radix Trichosanthis Cucumeroidis, Radix Berchemiae Yunnanensis according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention to be made up of following raw material medicaments: Herba Phyllanthi matsumuraes 30-50 part, Rhizoma Polygoni Cuspidati 20-40 part, Folium et Cacumen Broussonetiae Kazinoki 20-40 part, Herba adianti pedati 20-40 part, Herba Cerastii glomerati 15-25 part, Herba Artemisiae Scopariae 15-25 part, Radix Berberidis anhweiensis 15-25 part, Herba Pteridis Semipinnatae 9-15 part, Radix Trichosanthis Cucumeroidis 9-15 part, Radix Berchemiae Yunnanensis 9-15 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: Herba Phyllanthi matsumuraes 40 parts, Rhizoma Polygoni Cuspidati 30 parts, Folium et Cacumen Broussonetiae Kazinoki 30 parts, 30 parts, Herba adianti pedati, Herba Cerastii glomerati 20 parts, Herba Artemisiae Scopariae 20 parts, Radix Berberidis anhweiensis 20 parts, Herba Pteridis Semipinnatae 12 parts, Radix Trichosanthis Cucumeroidis 12 parts, Radix Berchemiae Yunnanensis 12 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Herba Phyllanthi matsumuraes: bitter, cold.Clearing away heat-damp and promoting diuresis, liver heat removing and eyesight improving.Cure mainly jaundice, dysentery, have loose bowels, edema, gonorrhea, infantile malnutrition, conjunctival congestion and swelling pain, hemorrhoid, venom.
Rhizoma Polygoni Cuspidati: bitter, is slightly cold.Return liver, gallbladder, lung meridian.Blood circulation promoting and blood stasis dispelling, dampness removing jaundice eliminating, heat-clearing and toxic substances removing.Cure mainly women's amenorrhea, dysmenorrhea, lochiostasis ， lumps in the chest and abdomen, rheumatic arthralgia, jaundice due to damp-heat, stranguria with turbid discharge leukorrhagia, injury from falling down, sore swollen toxin, burn due to hot liquid or fire.
Folium et Cacumen Broussonetiae Kazinoki: sweet, light is flat.Expelling wind and removing dampness, promoting blood circulation and stopping pain.Cure mainly rheumatic arthralgia, have loose bowels, dysentery, jaundice, edema, carbuncle furuncle, traumatic injury.
Herba adianti pedati: bitter, is slightly cold.Return lung, liver, urinary bladder channel.Heat-clearing and toxic substances removing, relieving stranguria by diuresis.Cure mainly cough due to lung-heat, dysentery, jaundice, urine leaching is puckery, carbuncle, scrofula, scalds.
Herba Cerastii glomerati: sweet, micro-hardship is cool.Return lung, stomach, Liver Channel.Heat clearing away, dampness removing, removing pathogenic heat from blood and toxic substance from the body.Cure mainly cold, fever, diarrhea due to damp-heat, discharging fresh blood stool, acute mastitis, furuncle, hypertension.
Herba Artemisiae Scopariae: micro-hardship, micro-pungent, is slightly cold.Return spleen, stomach, urinary bladder channel.Clearing away heat-damp and promoting diuresis, jaundice eliminating.Cure mainly jaundice, dysuria, eczema pruritus.
Radix Berberidis anhweiensis: bitter, cold.Heat clearing and damp drying, eliminating fire and detoxication.Cure mainly jaundice due to damp-heat, diarrhoea, dysentery, conjunctival congestion and swelling pain, pathopyretic ulcer, beriberoid pyretic arthralgia.
Herba Pteridis Semipinnatae: bitter, pungent, cool.Return liver, large intestine channel.Clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, removing toxic substances and promoting subsidence of swelling.Cure mainly dysentery, jaundice, conjunctival congestion and swelling pain, toothache, spit blood, bleeding hemorrhoids, traumatic hemorrhage, traumatic injury, furuncle furuncle and phyma, acute mastitis, skin pruritus, venom.
Radix Trichosanthis Cucumeroidis: bitter, cold.Return large intestine, stomach warp.Purge heat and promote the production of body fluid, dissipating blood stasis for subsidence of swelling.Cure mainly calentura excessive thirst, jaundice, constipation with heat retention, dysuria, amenorrhea, agalactia ， mass in the abdomen, carbuncle.
Radix Berchemiae Yunnanensis: bitter, micro-, cool.Heat clearing away, dampness removing, removing toxic substances.Cure mainly pyretic stranguria, jaundice, dysentery, leukorrhagia, traumatic injury.
The traditional Chinese medical science is thought, liver gallbladder damp-heat type infantile jaundice is many because of damp and hot pathogenic factor, and retardance liver and gall, mechanism of qi is obstructed, and catharsis is not normal, caused by bile is excessive.Herba Phyllanthi matsumuraes clearing away heat-damp and promoting diuresis, liver heat removing and eyesight improving in the present invention are monarch drug; Rhizoma Polygoni Cuspidati blood circulation promoting and blood stasis dispelling, dampness removing jaundice eliminating, heat-clearing and toxic substances removing, Folium et Cacumen Broussonetiae Kazinoki expelling wind and removing dampness, promoting blood circulation and stopping pain, Herba adianti pedati heat-clearing and toxic substances removing, relieving stranguria by diuresis are ministerial drug; Herba Cerastii glomerati clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, Herba Artemisiae Scopariae clearing away heat-damp and promoting diuresis, jaundice eliminating, Radix Berberidis anhweiensis heat clearing and damp drying, eliminating fire and detoxication, Herba Pteridis Semipinnatae clearing away heat-damp and promoting diuresis, cooling blood for hemostasis, removing toxic substances and promoting subsidence of swelling, Radix Trichosanthis Cucumeroidis purge heat promote the production of body fluid, dissipating blood stasis for subsidence of swelling, Radix Berchemiae Yunnanensis clearing away heat-damp and promoting diuresis detoxify.Find through clinical practice, to liver gallbladder damp-heat type infantile jaundice, there is unique curative effect, all medicines play clearing away heat-damp and promoting diuresis, liver heat removing and eyesight improving, dampness removing jaundice eliminating, expelling wind and removing dampness, heat-clearing and toxic substances removing, removing pathogenic heat from blood and toxic substance from the body, heat clearing and damp drying, cooling blood for hemostasis, effect of promoting the production of body fluid of purging heat altogether, reach the object for the treatment of liver gallbladder damp-heat type infantile jaundice.
Chinese medicine composition of the present invention was in 2008 to 2012 the routine patients of clinical observation liver gallbladder damp-heat type infantile jaundice 128, and clinical report is as follows:
1, physical data
In 128 routine patients, boy 66 example, girl 62 example, at minimum 4 months of age, maximum 6 years old, the course of disease was many at 2 days to 15 days, 3.5 years old mean age.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
icteric sclera, skin are yellow, yellowish urine, based on icteric sclera;
from the beginning of there being fever with aversion to cold, indigestion and loss of appetitely detest oil, nausea and vomiting, spiritlessness and weakness, or stool color is thin out;
there is eating and drinking without temperance, the medical histories such as hepatitis contact or applied chemistry goods medicine;
liver, spleen or gollbladder dilation, with tenderness or tenderness.
And have following symptom: yellow skin and eye, yellow distinct, generate heat thirsty, in the heart regretful Nang, xerostomia and bitter, tending to vomit of feeling sick, abdominal distention hypochondriac pain, constipation or be canescence, oliguria with yellow urine, red tongue, yellow and greasy fur, wiry and frequent pulse.
3, Therapeutic Method:
3.1 prescriptions: Herba Phyllanthi matsumuraes 40g, Rhizoma Polygoni Cuspidati 30g, Folium et Cacumen Broussonetiae Kazinoki 30g, Herba adianti pedati 30g, Herba Cerastii glomerati 20g, Herba Artemisiae Scopariae 20g, Radix Berberidis anhweiensis 20g, Herba Pteridis Semipinnatae 12g, Radix Trichosanthis Cucumeroidis 12g, Radix Berchemiae Yunnanensis 12g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 3 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 specify with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Cure: jaundice disappears, other transference cures, and lab index is normal;
Take a turn for the better: jaundice and other symptoms alleviate, bilirubin is normal or reduce, and other lab index take a turn for the better;
Do not heal: jaundice is not moved back or deepened, other symptoms and lab index are without improvement.
4.2 results: in 128 routine patients, cure 104 examples (81.3%), 22 examples that take a turn for the better (17.2%), and do not heal 2 examples (1.5%), and total effective rate is 98.5%.
5, model case
5.1 open up certain, female, 1 years old.Patient's binocular and whole skin jaundice, yellow bright-coloured, agitation is cryed, bowel movements, red tongue, yellow and greasy fur, wiry and frequent pulse.Be diagnosed as liver gallbladder damp-heat type infantile jaundice.Take medicine of the present invention, treat 1 course for the treatment of, binocular and whole skin xanthochromia obviously disappear, and continue to take 2 courses for the treatment of, all diseases all disappear, recovery from illness, follow up a case by regular visits to without recurrence after 1 year.
5.2 peaceful certain, man, 3 years old.Patient skin and binocular jaundice, yellow distinct, tending to vomit of feeling sick, agitation is cryed, constipation, oliguria with yellow urine, red tongue, yellow and greasy fur, wiry and frequent pulse.Be diagnosed as liver gallbladder damp-heat type infantile jaundice.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, skin and binocular xanthochromia obviously disappear, and continue to take 2 courses for the treatment of, all diseases all disappear, recovery from illness, follow up a case by regular visits to without recurrence after 1 year.
5.3 Qi, female, 4 years old.Patient's binocular and whole skin are yellow distinct, generate heat thirsty, xerostomia and bitter, nauseating tending to vomit, bowel movements, oliguria with yellow urine, red tongue, yellow and greasy fur, wiry and frequent pulse.Be diagnosed as.Take medicine of the present invention, every day 1 dose, after 1 course for the treatment of, binocular and whole skin xanthochromia obviously disappear, and continue to take 2 courses for the treatment of, all diseases all disappear, recovery from illness, follow up a case by regular visits to without recurrence after 1 year.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, treating a Chinese medicine composition for liver gallbladder damp-heat type infantile jaundice, is be made up of Herba Phyllanthi matsumuraes 30g, Rhizoma Polygoni Cuspidati 20g, Folium et Cacumen Broussonetiae Kazinoki 20g, Herba adianti pedati 20g, Herba Cerastii glomerati 15g, Herba Artemisiae Scopariae 15g, Radix Berberidis anhweiensis 15g, Herba Pteridis Semipinnatae 9g, Radix Trichosanthis Cucumeroidis 9g, Radix Berchemiae Yunnanensis 9g.
Embodiment 2, treating a Chinese medicine composition for liver gallbladder damp-heat type infantile jaundice, is be made up of Herba Phyllanthi matsumuraes 40g, Rhizoma Polygoni Cuspidati 30g, Folium et Cacumen Broussonetiae Kazinoki 30g, Herba adianti pedati 30g, Herba Cerastii glomerati 20g, Herba Artemisiae Scopariae 20g, Radix Berberidis anhweiensis 20g, Herba Pteridis Semipinnatae 12g, Radix Trichosanthis Cucumeroidis 12g, Radix Berchemiae Yunnanensis 12g.
Embodiment 3, treating a Chinese medicine composition for liver gallbladder damp-heat type infantile jaundice, is be made up of Herba Phyllanthi matsumuraes 50g, Rhizoma Polygoni Cuspidati 40g, Folium et Cacumen Broussonetiae Kazinoki 40g, Herba adianti pedati 40g, Herba Cerastii glomerati 25g, Herba Artemisiae Scopariae 25g, Radix Berberidis anhweiensis 25g, Herba Pteridis Semipinnatae 15g, Radix Trichosanthis Cucumeroidis 15g, Radix Berchemiae Yunnanensis 15g.
Claims (2)
1. treat the Chinese medicine composition of liver gallbladder damp-heat type infantile jaundice for one kind, it is characterized in that, it is made up of following raw material medicaments: Herba Phyllanthi matsumuraes 30-50 part, Rhizoma Polygoni Cuspidati 20-40 part, Folium et Cacumen Broussonetiae Kazinoki 20-40 part, Herba adianti pedati 20-40 part, Herba Cerastii glomerati 15-25 part, Herba Artemisiae Scopariae 15-25 part, Radix Berberidis anhweiensis 15-25 part, Herba Pteridis Semipinnatae 9-15 part, Radix Trichosanthis Cucumeroidis 9-15 part, Radix Berchemiae Yunnanensis 9-15 part.
2. Chinese medicine composition according to claim 1, it is characterized in that, it is made up of following raw material medicaments: Herba Phyllanthi matsumuraes 40 parts, Rhizoma Polygoni Cuspidati 30 parts, Folium et Cacumen Broussonetiae Kazinoki 30 parts, 30 parts, Herba adianti pedati, Herba Cerastii glomerati 20 parts, Herba Artemisiae Scopariae 20 parts, Radix Berberidis anhweiensis 20 parts, Herba Pteridis Semipinnatae 12 parts, Radix Trichosanthis Cucumeroidis 12 parts, Radix Berchemiae Yunnanensis 12 parts.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007191A (en) * | 2012-11-23 | 2013-04-03 | 邹洪胜 | Chinese medicinal composition for treating jaundice |
| CN103990081A (en) * | 2014-06-17 | 2014-08-20 | 刘青振 | Traditional Chinese medicine composition and application thereof in preparation of medicine for treating infant jaundice |
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2016
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103007191A (en) * | 2012-11-23 | 2013-04-03 | 邹洪胜 | Chinese medicinal composition for treating jaundice |
| CN103990081A (en) * | 2014-06-17 | 2014-08-20 | 刘青振 | Traditional Chinese medicine composition and application thereof in preparation of medicine for treating infant jaundice |
Non-Patent Citations (1)
| Title |
|---|
| 赵培侠等: "茵虎汤治疗新生儿黄疸50例", 《陕西中医》 * |
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