CN104997854A - Traditional Chinese medicine for treating interstitial keratitis - Google Patents
Traditional Chinese medicine for treating interstitial keratitis Download PDFInfo
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- CN104997854A CN104997854A CN201510518295.6A CN201510518295A CN104997854A CN 104997854 A CN104997854 A CN 104997854A CN 201510518295 A CN201510518295 A CN 201510518295A CN 104997854 A CN104997854 A CN 104997854A
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Abstract
The invention relates to a traditional Chinese medicine for treating interstitial keratitis. The traditional Chinese medicine is prepared from the following crude drugs in parts by weight: 10 parts of all-grass of bieberstein carlina, 6 parts of piper cubeba, 15 parts of sedum lineare, 30 parts of polygonum dissitiflorum, 6 parts of centaurium pulchellum, 15 parts of ainsliaea henryi, 8 parts of ligularia tsangchanensis, and 8 parts of silver vine. Clinical experiments prove that the traditional Chinese medicine can be used for safely and effectively treating interstitial keratitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of interstitial keratitis.
Background technology
Interstitial keratitis or title corneal stroma inflammation, also referred to as non-ulcerative keratitis, refer to the non-ulcerative, the nonsuppurative inflammation that occur in corneal stroma.Treponema pallidum, tubercule bacillus, leprosy bacillus and herpes simplex virus infection are the common causes of disease.Only make a presentation with regard to syphilis interstitial keratitis herein.The main clinic symptoms of this disease is ocular pain, photophobia, shed tears.Blepharospasm companion ciliary congestion; Main clinical characteristics is that corneal stroma edema infiltrates, and often vascularization occurs subsequently, vision is in declining in various degree.Interstitial keratitis belongs to " interstitial keratitis " category of motherland's medical science.Primary disease belongs to wind wheel disease, and planted agent is in liver and gall, therefore primary disease is many steams in order because wind-heat of liver channel or liver and gall pyretic toxicity accumulate, the body fluid of heat, and blood stasis stagnates and causes; Or evil poison volt for a long time, consume cloudy liquid, the hepatic and renal YIN deficiency, caused by hyperactivity of deficient fire; Caused by dampness-heat of the liver, person's course of disease is longer.This onset of disease To Be Protected from Heat photophobia, eyelid difficulty is opened, eyeball pain, visual deterioration, and wheel holding is dark red, or conjunctiva being red and turbid, interstitial keratitis, or muddy from central authorities or periphery, unrestrainedly gradually covers whole black eyeball, causes lustreless cornea, as ground glass shape.While becoming with cornea disease, iridocyclitis or dry scarce can be there is, therefore notably, in order to avoid deal with improperly, cause blind.Primary disease is dialectical, must sift the cause of disease.Work corneal opacity, ciliary hyperemia, the photophobia person of shedding tears is caused by wind-heat of liver channel; Work corneal opacity, eyeball dull pain person is caused by retention of damp-heat in the interior; The black eyeball hyperemic arterioles extended of work, ciliary congestion, the twinge person of shedding tears is caused by liver and gall pyretic toxicity; If recurrent exerbation, black eyeball clouding, mild ciliary congestion, the not aobvious person of pain is caused by hyperactivity of deficient fire.
Medical material present Research involved in the present invention is as follows:
Herba Carlinae biebersteinii [another name] Nitraria sibirica, acid fat, breathe out not.[source] medical material Ji Yuan: be the fruit of zygophyllaceae plant nitraria schoberi and tingia Cortex Acanthopanacis Radicis.Gather and store: gathering during fruit maturation in autumn, dry.[nature and flavor] sweet acid; Micro-salty; Temperature.[return through] spleen; Liver; Kidney channel.[function cures mainly] strengthening the spleen and stomach; Replenishing QI and blood; Tune have through.Main insufficiency of the spleen lack of appetite; Dyspepsia; Deficiency of both QI and blood; Asthenic body; Have through uncomfortable.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Cubeb [another name] clear eggplant, PiLing Fructus Solani melongenae, cubeb, complete eggplant.The fruit that [source] is Piperaceae plant Fructus Litseae or canella cubeb litsen tree, fruit fully grow up and immaturity still in cyan time gather, connecting Fruit branch takes, and dries.After drying, take fruit (every palpus connects stalklet).[nature and flavor] are pungent, warm.[return through] returns spleen, kidney channel.[function cures mainly] warming the spleen and kidney, invigorating the stomach and promoting digestion.Control food stagnation flatulence, coldness and pain in the epigastrium, regurgitation is vomitted, increased borborygmus and diarrhea, dysentery, accumulation of phlegm in the hypochondrium.[usage and dosage] takes orally: decoct soup, 1.5 ~ 6g.[attention] deficiency of YIN blood system has heat, and fever and cough is forbidden.[extracts] " China's book on Chinese herbal medicine ".
Herba Sedi Linearis [another name] burns grass, flame careless, Herba Sedi Multicaulis, Herba Portulacae Grandiflorae, Drymoglossum heterophyllum (C. Chr) Ching, Canis familiaris L. tooth half, imperial pasture and water, HUISHENGCAO, ricebird tongue, Wan Niancao, Herba Portulacae Grandiflorae, golden small arms propellant, Canis familiaris L. tooth lobe, little Herba Sedi Multicaulis, sharp leaf Herba Sedi Linearis list, in vain opening, HERBA SEDI SARMENTOSI, pig tooth, Herba Senecionis Chrysanthemoidis, poultry grass, the little Herba Sedi Sarmentosi of Guan Ye.[source] medical material Ji Yuan: be the stem and leaf of crassulaceae plants Herba Sedi Linearis.Gather and store: using fresh herb is with adopting; Or the summer, Qiu Liangji, extract Herb, clean, decontrol in water and scald, pick up, to dry or a heatable brick bed is done.[nature and flavor] are sweet; Light; Cold.[return through] heart; Lung; Liver; Spleen channel.[function cures mainly] heat-clearing and toxic substances removing; Dampness removing; Hemostasis.Main laryngopharynx swelling and pain; Conjunctival congestion toxic swelling; Pyretic toxicity carbuncle; Furuncle; Erysipelas; Herpes zoster; Burn and scald; Venom; Jaundice; Damp-heat dysentery; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Verruca plana.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Polygonum dissitiflorum Hemsl [another name] returns in vain, Lian Yaci.[source] medical material Ji Yuan: be the herb of polygonaceae plant Polygonum dissitiflorum Hemsl.Gather and store: the florescence gathers herb, using fresh herb or dry.[return through] Liver Channel, kidney channel, urinary bladder channel.[function cures mainly] heat-clearing and toxic substances removing; Dampness removing.Main acute, chronic hepatitis; Urine leaching pain; Venom.[usage and dosage] takes orally: decoct soup, 30 ~ 60g.[extracts] " China's book on Chinese herbal medicine ".
Herba centaurll altaici [source] medical material Ji Yuan: be the wounded in the battle herb of gentianaceae plant Centaurium meyeri Druce.Gather and store: when adopting when blooming, cleaning, dry.[nature and flavor] are bitter; Cold in nature.[return through] liver; Stomach warp.[function cures mainly] heat-clearing and toxic substances removing.Main hepatitis; Cholecystitis; Have a headache and fever; Toothache; Tonsillitis.[usage and dosage] takes orally: decoct soup, 5 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".
Two Lang Jian [another name] are shown in blood grass.[source] medical material Ji Yuan: be the herb of the long fringe Ainsliaea fragrans Champ. of feverfew.Gather and store: summer, autumn gather, using fresh herb or cutting are dried.[nature and flavor] bitter in the mouth; Acid; Cool in nature.The heat clearing away of [function cures mainly] dissipating blood stasis; Relieving cough and asthma.Main traumatic injury; Blood stasis swells and ache; Venom; Cough due to lung-heat; Asthma.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
The sharp leaf Farfugium kaemferi of Cangshan Farfugium kaemferi [another name].[source] Compositae Cangshan Farfugium kaemferi, is used as medicine with root.[nature and flavor] are bitter, temperature.[return through] returns lung kidney two warp.[function cures mainly] cold expelling, lung moistening sending down the abnormal ascending QI, preventing phlegm from forming and stopping coughing, diuresis.Cure mainly cough due to wind and cold, bronchitis, pulmonary tuberculosis hemoptysis, pharyngolaryngitis.[usage and dosage] takes orally: decoct soup, 4 ~ 12g.[extracts] " China's book on Chinese herbal medicine ".
Ramulus et Folium Actinidiae Polygamae [another name] sky knotweed, rattan sky knotweed, sky knotweed wood, lily feet branch, containing water wine, milk milk, Cortex schizophragmatis integrifolii radicis, carambola, sheep milk Codonopsis ussuriensis Hemsl..[source] medical material Ji Yuan: be the branch and leaf of Actinidiaceae plant Ramulus et Folium Actinidiae Polygamae.Gather and store: spring, autumn adopt, drying or using fresh herb.[nature and flavor] are pungent; Temperature; [return through] liver; Kidney channel.[function cures mainly] remove rheumatism; Antalgic; Lump in the abdomen.Main apoplexy and hemiplegia; Anemofrigid-damp arthralgia; Pain in the lumbar region; Colic; Lump in the abdomen; Diarrhea due to disorder of qi; Tuberculoid leprosy wind.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[attention] this product pungent temperature consumption gas, should not take for a long time.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of interstitial keratitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing interstitial keratitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of interstitial keratitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Carlinae biebersteinii 10 parts, cubeb 6 parts, Herba Sedi Linearis 15 parts, Polygonum dissitiflorum Hemsl 30 parts, Herba centaurll altaici 6 parts, two Lang Jian 15 parts, Cangshan Farfugium kaemferi 8 parts, Ramulus et Folium Actinidiae Polygamae 8 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and interstitial keratitis patient 240 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 120 example and matched group 120 example at random, treatment group man 62 example, female 58 example, 13 ~ 25 years old age; Matched group man 60 example, female 60 example, 12 ~ 27 years old age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national interstitial keratitis clinical speciality:
(1), syphilis or tuberculosis medical history, teenager is common.
(2), keep in dark place, shed tears, visual deterioration.
(3), early stage edema of corneal endothelium, trickle deposit, with uveitis.
(4), the first slight mist-like bleary of cornea periphery Medium Culture, ciliary congestion, by extending partially into cornea surrounding, sometimes stretch out ligule muddiness to stretch to CC, total corneal is that white diffusivity is muddy, newborn with hairbrush shape deep-level blood vessel nebula, stretches into deep layer substrate.
(5), course of disease several weeks, once the corneal opacity absorbs, pannus left over permanent vestige to the several months.
(6), Fahrenheit or the Kahn reaction positive.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 2 times; 3 weeks courses for the treatment of.
Matched group external 0.1% dexamethasone eye dropping of eye drops, every 2 hours 1 time, 1% atropine eye drop eye drip.3 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: transference cure, inflammatory resolution, Medium Culture remains cicatrix;
Effective: symptom inflammation alleviates;
Invalid: symptom inflammation is without improvement or increase the weight of.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment interstitial keratitis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Herba Carlinae biebersteinii 10 grams, cubeb 6 grams, Herba Sedi Linearis 15 grams, Polygonum dissitiflorum Hemsl 30 grams, Herba centaurll altaici 6 grams, two Lang Jian 15 grams, Cangshan Farfugium kaemferi 8 grams, Ramulus et Folium Actinidiae Polygamae 8 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of interstitial keratitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Herba Carlinae biebersteinii 10 grams, cubeb 6 grams, Herba Sedi Linearis 15 grams, Polygonum dissitiflorum Hemsl 30 grams, Herba centaurll altaici 6 grams, two Lang Jian 15 grams, Cangshan Farfugium kaemferi 8 grams, Ramulus et Folium Actinidiae Polygamae 8 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of interstitial keratitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Herba Carlinae biebersteinii 10 grams, cubeb 6 grams, Herba Sedi Linearis 15 grams, Polygonum dissitiflorum Hemsl 30 grams, Herba centaurll altaici 6 grams, two Lang Jian 15 grams, Cangshan Farfugium kaemferi 8 grams, Ramulus et Folium Actinidiae Polygamae 8 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of interstitial keratitis.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of interstitial keratitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Carlinae biebersteinii 10 parts, cubeb 6 parts, Herba Sedi Linearis 15 parts, Polygonum dissitiflorum Hemsl 30 parts, Herba centaurll altaici 6 parts, two Lang Jian 15 parts, Cangshan Farfugium kaemferi 8 parts, Ramulus et Folium Actinidiae Polygamae 8 parts.
2. a kind of Chinese medicine being used for the treatment of interstitial keratitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Carlinae biebersteinii 10 parts, cubeb 6 parts, Herba Sedi Linearis 15 parts, Polygonum dissitiflorum Hemsl 30 parts, Herba centaurll altaici 6 parts, two Lang Jian 15 parts, Cangshan Farfugium kaemferi 8 parts, Ramulus et Folium Actinidiae Polygamae 8 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of interstitial keratitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Carlinae biebersteinii 10 parts, cubeb 6 parts, Herba Sedi Linearis 15 parts, Polygonum dissitiflorum Hemsl 30 parts, Herba centaurll altaici 6 parts, two Lang Jian 15 parts, Cangshan Farfugium kaemferi 8 parts, Ramulus et Folium Actinidiae Polygamae 8 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of interstitial keratitis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Carlinae biebersteinii 10 parts, cubeb 6 parts, Herba Sedi Linearis 15 parts, Polygonum dissitiflorum Hemsl 30 parts, Herba centaurll altaici 6 parts, two Lang Jian 15 parts, Cangshan Farfugium kaemferi 8 parts, Ramulus et Folium Actinidiae Polygamae 8 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
Priority Applications (1)
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| CN201510518295.6A CN104997854A (en) | 2015-08-21 | 2015-08-21 | Traditional Chinese medicine for treating interstitial keratitis |
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| CN201510518295.6A CN104997854A (en) | 2015-08-21 | 2015-08-21 | Traditional Chinese medicine for treating interstitial keratitis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168627A (en) * | 2015-09-08 | 2015-12-23 | 粘芙蓉 | Traditional Chinese medicine for treating pityriasis versicolor |
| CN105233221A (en) * | 2015-11-03 | 2016-01-13 | 宁波优美科新材料有限公司 | Traditional Chinese medicine for treating scabies |
-
2015
- 2015-08-21 CN CN201510518295.6A patent/CN104997854A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168627A (en) * | 2015-09-08 | 2015-12-23 | 粘芙蓉 | Traditional Chinese medicine for treating pityriasis versicolor |
| CN105233221A (en) * | 2015-11-03 | 2016-01-13 | 宁波优美科新材料有限公司 | Traditional Chinese medicine for treating scabies |
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Application publication date: 20151028 |