CN105125865A - Traditional Chinese medicine for treating optic atrophy - Google Patents
Traditional Chinese medicine for treating optic atrophy Download PDFInfo
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- CN105125865A CN105125865A CN201510528135.XA CN201510528135A CN105125865A CN 105125865 A CN105125865 A CN 105125865A CN 201510528135 A CN201510528135 A CN 201510528135A CN 105125865 A CN105125865 A CN 105125865A
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Abstract
The invention relates to a traditional Chinese medicine for treating optic atrophy. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 20 parts of eclipta alba, 15 parts of herba epimedii, 12 parts of rhizoma curculiginis, 15 parts of drymoglossum piloselloides presl, 20 parts of ficus wightiana, 15 parts of polystichum craspedosorum, 12 parts of heliotropium indicum, and 6 parts of Paphiopedilum concolor Tang et Wang. The clinical experiment proves that the traditional Chinese medicine can safely and effectively treat optic atrophy.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of optic atrophy.
Background technology
Optic atrophy be a kind of due to the various cause of disease cause optic nerve fiber conduction function to produce the optic nerve degenerative change of obstacle.If atrophy is called ascending optic atrophy because retina and ganglion cell cause, and atrophy is called descending optic atrophy by below lateral geniculate body as optic chiasma, tractus opticus, optic nerve cause.General performance by optic disc is divided into primary optic atrophy and secondary optic atrophy clinically.Primary optic atrophy (or atrophia nervi optici simplex) optic disc sharpness of border, color and luster is pale (partly or entirely) obviously, can see cribriform plate of sclera hole.Secondary optic atrophy (or non-atrophia nervi optici simplex) optic disc obscure boundary, color and luster canescence or wax yellow, color and luster is comparatively dark, and cribriform plate of sclera hole loses, optic disc edge and around and retina can see the abnormal changes such as Blood vessel pattern, pigment be disorderly.The total pathogenesis of primary disease is sweat pore obstruction in order, causes blurring of vision.It is formed and deficiency of both the liver and kidney, asthenia of essence and blood; Deficiency of spleen-YANG and kidneyYANG is precise and tiny not to be changed; Prolonged illness the heart-nutriment loses; The calentura later stage, cloudy essence consumption wound; Seven emotions pent-up, liver is lost bar and reaches closely related.In addition, head eye wound, oncothlipsis, encephalic operation etc. make order system impaired, and the venation stasis of blood is stagnant, and profound mansion impatency also can form primary disease.
Medical material present Research involved in the present invention is as follows:
Herba Ecliptae [another name] Mo Liancao, floods and droughts lotus, Alternanthera sessilis (L.) DC., spend Sesarmae dehaani grass, Herba Ecliptae, wild sunflower, black dish, tusche grass, careless, the inkweed of prepared Chinese ink, Herba Ecliptae in vain.[source] this product is the dry aerial parts of feverfew Eclipta prostrata.Tap when the flowers are in blossom, dry.[nature and flavor] are sweet, sour, cold.[return through] returns kidney, Liver Channel.[function cures mainly] nourishing the liver and kidney, cooling blood for hemostasis.For odontoseisis, early whitening of beard and hair, vertigo and tinnitus, soreness of the waist and knees, YinXuXueRe, haematemesis, epistaxis, hematuria, dysentery, metrostaxis, traumatic hemorrhage.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] spleen-kidney vacuity cold person avoids clothes.[extracts] " China's book on Chinese herbal medicine ".
Herba Epimedii [another name] Epimedium, Herba Epimedii, Birdfoot, trident wind, epilepsy, Herba Epimedii, three furculas, Herba Saniculae lamelligerae, Rhizoma Smilacis Chinensis.[source] this product is the dry aerial parts of Berberidaceae plant Herba Epimedii, Epimedium sagittatum, E. Pubescens, Epimedium wushanense or Herba Epimedii.Tap when summer, autumn, stem and leaf was luxuriant, the thick stalk of removing and impurity, dry or dry in the shade.[nature and flavor] acrid, sweet, warm.[return through] returns liver, kidney channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] empty YANG transmission is lifted, and nocturnal emission is more than, just red xerostomia, strong sun not flaccidity avoid it.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Curculiginis [another name] Rhizoma Curculiginis root, thatch claw, tragopogon pratensis l., unipods Rhizoma Curculiginis, curled-up dragon grass, wind sedge, cold meal grass, little RHIIZOMA CURCULIGINIS, RHIIZOMA CURCULIGINIS, Radix Scorzonerae Albicaulis, unipods silk thatch, Huang Mao ginseng, unipods Huang Mao, the solely green Rhizoma Imperatae of foot, sky palm fibre, brown, the native Radix Paeoniae Alba in mountain, suppressing the hyperactive liver potato, dish palm fibre, mountain Cymbidium ensifolium (L.) Sw..[source] this product is the dry rhizome of amrallid Rhizoma Curculiginis.Autumn, season in winter two excavate, removing root head and fibrous root, cleaning, drying.[nature and flavor] are pungent, heat.[return through] returns kidney,liver,spleen warp.[function cures mainly] kidney-replenishing, bone and muscle strengthening, dispelling cold and dampness.For sexual impotence cold sperm, muscles and bones flaccidity is soft, the cold numbness of waist knee joint, yang deficiency cold diarrhea.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] all fevers due to yin deficiency without exception, cough, haematemesis, epistaxis, tooth blood, hematuria, stranguria with blood, seminal emission nebulousurine, sexual intercourse in dream, lumbago due to renal deficiency, foot knee joint is unable, hyperactivity of deficient fire, xerostomia pharyngalgia, mental confusion sexual impotence, the water essence that dries up exhausts, and can not breed, the lonely positive depletion of YIN of old man, incontinence of urine consumption of essence, blood deficiency can not nourishing muscle and tendon, so that hemiplegia flaccidity syndrome and arthralgia syndrome, stomach man pathogenic heat can not kill paddy, the noisy easy famine of stomach man asthenic fire, and three disappear five types of jaundice, yin asthenia generating intrinsic heat exogenous cold, sun faints fiery pole like cards such as water, and method is also forbidden.[extracts] " China's book on Chinese herbal medicine ".
The skilful root rattan of Drymoglossum Herba Drymoglossi [another name], the company's of flying grass, star hair Drymoglossum Herba Drymoglossi, Drymoglossum Herba Drymoglossi, Semen Benincasae dish.[source] fern Polypodiaceae Drymoglossum Herba Drymoglossi platymiscium Drymoglossum Herba Drymoglossi is with all herbal medicine.The whole year can adopt, and cleans, using fresh herb or dry.[nature and flavor] slightly sweet flavor, slightly cool in nature.[return through] returns liver, kidney channel.[function cures mainly] eliminating inflammation and expelling toxin, dispelling wind stopping cough.To harness the Yellow River subcutaneous ulcer, tuberculous lymphadenitis, parotitis, cough hemoptysis, rheumatic ostalgia, breast carcinoma, constipation due to dry stool.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] all gate of vitality's heateds, strong sun not flaccidity, have damp and hot, and the puckery person of urine leaching avoids clothes.[extracts] " China's book on Chinese herbal medicine ".
Shaft of a writing brush banyan [another name] shaft of a writing brush tree, paint uncle, bird banyan, red fruit fig-tree.[source] this product is that Moraceae shaft of a writing brush banyan is used as medicine with root, leaf.[nature and flavor] sweet, micro-hardship, flat.[return through] returns liver, gallbladder meridian.[function cures mainly] relieves inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Polystichum craspedosorum (Maxim.) Diels. [another name] Fructus Hordei Vulgaris tiller, wheat tiller, Fructus Hordei Vulgaris hair, large Polystichum craspedosorum (Maxim.) Diels..[source] is the herb of Dryopteridaceae plant Polystichum craspedosorum (Maxim.) Diels., gathers and stores: the whole year all can gather.Dig out afterwash, using fresh herb or dry.[nature and flavor] are bitter; Cold.[return through] enters the heart, liver, large intestine three warp.[function cures mainly] heat-clearing and toxic substances removing.Main acute mastitis; Furuncle and phyma; Enteritis.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Herba Heliotroph [another name] squid grass, careless, the timothy grass of speckle, trunk Huang, trunk grass, cuttlefish moss, towser tail, trunk flower, garden heliotrope, Canis familiaris L. tail worm, corner Soviet Union, eave tile Serpentis, smelly Fructus Citri Limoniae.[source] medical material Ji Yuan: be herb or the root of comfrey Herba Heliotroph.Gather and store: autumn gathers, using fresh herb or dry.[nature and flavor] are bitter; Flat.[return through] lung; Urinary bladder channel.[function cures mainly] diuresis; Detumescence; Removing toxic substances.Main pneumonia; Empyema; Pharyngalgia; Oral erosion; Vesical calculus; Carbuncle.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[attention] is not taken by pregnant women.[extracts] " China's book on Chinese herbal medicine ".
Philippine Paphiopedilum (Concolor Paphiopedilum) [another name] red straw sandals, paphio-pedilum concolor (par. Ex Balem.)pfiiz., lion tail, Herba Senecionis Kirilowi.[source] medical material Ji Yuan: be the herb of the homochromy pocket orchid of orchid.Gather and store: summer, autumn gather, using fresh herb or dry.[nature and flavor] bitter in the mouth; Acid; Property is put down.[return through] returns spleen channel.[function cures mainly] heat-clearing and toxic substances removing; Dissipating blood stasis for subsidence of swelling.Main furuncle swelling toxin; Venom; Splenomegaly; Pulmonary tuberculosis hemoptysis; Traumatic injury.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of optic atrophy, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing optic atrophy.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of optic atrophy, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Ecliptae 20 parts, Herba Epimedii 15 parts, Rhizoma Curculiginis 12 parts, Drymoglossum Herba Drymoglossi 15 parts, shaft of a writing brush banyan 20 parts, Polystichum craspedosorum (Maxim.) Diels. 15 parts, Herba Heliotroph 12 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and optic atrophy 110 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 60 example and matched group 50 example at random, 18 ~ 60 years old treatment group age, 32 years old mean age; 24 ~ 55 years old matched group age, 34 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national optic atrophy clinical speciality:
(1), tabes dorsalis, intracranial tumor, retrobulbar neuritis and trauma history.
(2), vision obviously declines or blind.
(3), look disk boundary is clear, pale asphyxia, physiological depression expand, sieve plate hole is high-visible, blood vessel attenuates.
(4), visual field concentric contraction.
(5), secondary optic atrophy caused by optic neuritis and edema, disk boundary is fuzzy, and sieve plate hole is unclear, and the visible pigmentation of retina, blood vessel attenuates.
(6), underwent eye-ground vascular fluorescence visualization loses fluorography.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.One month course for the treatment of.
Matched group oral vitamin B, 2 are each, every day 1 time; Inosine, 0.2 ~ 0.6g, 3 times on the one.One month course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: vision restoration is to more than 1.0, and central region dim spot disappears;
Effective: vision improves more than 4 row, central region dim spot reduces or absolute scotoma becomes relative scotoma;
Effective: vision improves more than 2 row, and the visual field is unchanged;
Invalid: vision is identical with before treatment with the visual field or make retrogress.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment optic atrophy, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Herba Ecliptae 20 grams, Herba Epimedii 15 grams, Rhizoma Curculiginis 12 grams, Drymoglossum Herba Drymoglossi 15 grams, shaft of a writing brush banyan 20 grams, Polystichum craspedosorum (Maxim.) Diels. 15 grams, Herba Heliotroph 12 grams, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of optic atrophy.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Herba Ecliptae 20 grams, Herba Epimedii 15 grams, Rhizoma Curculiginis 12 grams, Drymoglossum Herba Drymoglossi 15 grams, shaft of a writing brush banyan 20 grams, Polystichum craspedosorum (Maxim.) Diels. 15 grams, Herba Heliotroph 12 grams, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of optic atrophy.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Herba Ecliptae 20 grams, Herba Epimedii 15 grams, Rhizoma Curculiginis 12 grams, Drymoglossum Herba Drymoglossi 15 grams, shaft of a writing brush banyan 20 grams, Polystichum craspedosorum (Maxim.) Diels. 15 grams, Herba Heliotroph 12 grams, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of optic atrophy.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of optic atrophy, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Ecliptae 20 parts, Herba Epimedii 15 parts, Rhizoma Curculiginis 12 parts, Drymoglossum Herba Drymoglossi 15 parts, shaft of a writing brush banyan 20 parts, Polystichum craspedosorum (Maxim.) Diels. 15 parts, Herba Heliotroph 12 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 parts.
2. a kind of Chinese medicine being used for the treatment of optic atrophy as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Ecliptae 20 parts, Herba Epimedii 15 parts, Rhizoma Curculiginis 12 parts, Drymoglossum Herba Drymoglossi 15 parts, shaft of a writing brush banyan 20 parts, Polystichum craspedosorum (Maxim.) Diels. 15 parts, Herba Heliotroph 12 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of optic atrophy as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Ecliptae 20 parts, Herba Epimedii 15 parts, Rhizoma Curculiginis 12 parts, Drymoglossum Herba Drymoglossi 15 parts, shaft of a writing brush banyan 20 parts, Polystichum craspedosorum (Maxim.) Diels. 15 parts, Herba Heliotroph 12 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of optic atrophy as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Ecliptae 20 parts, Herba Epimedii 15 parts, Rhizoma Curculiginis 12 parts, Drymoglossum Herba Drymoglossi 15 parts, shaft of a writing brush banyan 20 parts, Polystichum craspedosorum (Maxim.) Diels. 15 parts, Herba Heliotroph 12 parts, Philippine Paphiopedilum (Concolor Paphiopedilum) 6 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| CN201510528135.XA CN105125865A (en) | 2015-08-25 | 2015-08-25 | Traditional Chinese medicine for treating optic atrophy |
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| CN201510528135.XA CN105125865A (en) | 2015-08-25 | 2015-08-25 | Traditional Chinese medicine for treating optic atrophy |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106267023A (en) * | 2016-09-30 | 2017-01-04 | 李先强 | A kind of active pills for improving acuity of sight for optic atrophy |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1850218A (en) * | 2006-03-09 | 2006-10-25 | 北京市眼科研究所 | Chinese medicine composition for treating optic atrophy and preparing method therefor |
| CN103656290A (en) * | 2013-12-11 | 2014-03-26 | 张有富 | Medicine for treating optic atrophy and preparation method of medicine |
| CN104435803A (en) * | 2014-10-28 | 2015-03-25 | 王春磊 | Traditional Chinese medicine preparation for treating liver-kidney deficiency type optic atrophy |
-
2015
- 2015-08-25 CN CN201510528135.XA patent/CN105125865A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1850218A (en) * | 2006-03-09 | 2006-10-25 | 北京市眼科研究所 | Chinese medicine composition for treating optic atrophy and preparing method therefor |
| CN103656290A (en) * | 2013-12-11 | 2014-03-26 | 张有富 | Medicine for treating optic atrophy and preparation method of medicine |
| CN104435803A (en) * | 2014-10-28 | 2015-03-25 | 王春磊 | Traditional Chinese medicine preparation for treating liver-kidney deficiency type optic atrophy |
Non-Patent Citations (1)
| Title |
|---|
| 唐鸥: "视神经萎缩辨治经验", 《上海中医药杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106267023A (en) * | 2016-09-30 | 2017-01-04 | 李先强 | A kind of active pills for improving acuity of sight for optic atrophy |
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Application publication date: 20151209 |