CN105687732A - Traditional Chinese medicine for treating erythema multiforme - Google Patents

Traditional Chinese medicine for treating erythema multiforme Download PDF

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Publication number
CN105687732A
CN105687732A CN201610102314.1A CN201610102314A CN105687732A CN 105687732 A CN105687732 A CN 105687732A CN 201610102314 A CN201610102314 A CN 201610102314A CN 105687732 A CN105687732 A CN 105687732A
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parts
radix
chinese medicine
erythema multiforme
herba
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包玲丽
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/77Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention relates to a traditional Chinese medicine for treating erythema multiforme. The traditional Chinese medicine comprises, by weight, 12 parts of persicaria perfoliata roots, 15 parts of allium victorialis, 15 parts of radix crepidis ligneae, 10 parts of gymnema sylvestre schult, 6 parts of lysimachia glaucina franch, 9 parts of ipomoea pes-caprae, 12 parts of orchidaceae pecteilis and 8 parts of sapindus delavayi. The traditional Chinese medicine has the advantage that as proved by clinical experiments, the erythema multiforme can be safely and effectively treated by the traditional Chinese medicine.

Description

A kind of Chinese medicine for treating erythema multiforme
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for treating erythema multiforme。
Background technology
Erythema multiforme, has another name called erythema multiforme exudativu, is a kind of agnogenic acute inflammation dermatoses, is often accompanied by mucosal injury, also can with visceral lesion time serious。Primary disease is apt to occur in spring and autumn, and female patient, more than male, is more common in child and youth。Generally falling ill urgency, there are the prodromes such as heating, discomfort, pharyngalgia, watery nasal discharge, cough in 1 week before skin lesion in about 1/3 patient。Primary disease is relatively common, spring, Qiu Haofa。Prognosis bona, generally can spontaneous recovery, but can sending out again of having。Erythema multiforme is a kind of to exceed the erythema dermatosis for feature that skin is target shape, often symmetrical。
" General Treatise on the Cause and Symptoms of Diseases " is called " cold sore ";Golden Mirror of Medicine is because of its " shape is opal such as ", therefore is also called " erythema multiforme ";Also with good grounds primary disease often shows effect when wild goose comes, and is called " wild goose be the wind comes from " and " wild goose waits skin ulcer "。In addition with " itching eruption due to wind-heat in blood ", " erythema multiforme " etc.。Its symptom relevant, Golden Mirror of Medicine vividly describe into: " from the beginning of shape such as opal, honorable flicker, no pus depletion of blood, but sufferings are seldom, for a long time then nearly shin。" etiology and pathogenesis aspect, " General Treatise on the Cause and Symptoms of Diseases " thinks that caused by ferritic blood deficiency person " heavily tactile wind and cold ", Ming Dynasty's " skin infection experience pandect " then thinks that primary disease is to be formed by " Liver Channel heat in blood, spleen channel is damp and hot, wind and heat in the lung meridian " is sympathetic。
Medical material present Research involved in the present invention is as follows:
Radix Polygoni Perfoliati [another name] river root of Pennisetum centrasiaticum Tzvel.。[source] medical material Ji Yuan: for the root of polygonaceae plant Herba Polygoni Perfoliati。Gather and store: excavating root summer, Ex-all earth, using fresh herb or dry。[nature and flavor] acid;Bitter;Property is put down。[return through] returns Liver Channel。[function cures mainly] removing toxic substances and promoting subsidence of swelling。Main boil on the nape opposite the mouth;Hemorrhoid;Anal fistula。[usage and dosage] takes orally: decoct soup, 9~15g。[extracts] " China's book on Chinese herbal medicine "。
Herba Alii fistulosi [another name] lattice Herba Alii fistulosi, Herba Alii fistulosi, every Herba Alii fistulosi, deer ear Herba Alii fistulosi, angle Herba Alii fistulosi, sky Bulbus Allii, Herba Goodyerae biflorae。[source] medical material Ji Yuan: for the bulb of liliaceous plant Herba Alii fistulosi。Gather and store: summer, autumn excavate, cleaning, using fresh herb。[nature and flavor] acrid in the mouth;Warm in nature。[return through] lung meridian。[function cures mainly] dissipating blood stasis;Hemostasis;Removing toxic substances。Main traumatic injury;Blood stasis swells and ache;Epistaxis;Sore, carbuncle and painful swelling。[usage and dosage] takes orally: decoct soup, 15~30g。[extracts] " China's book on Chinese herbal medicine "。
Radix Crepidis Ligneae [another name] horse hair ginseng, Herba Ceratophylli Demeersi, Trimeresurus stejnegeri, spire Radix Crepidis Ligneae, Kochia scoparia, brush handle Herba Asari, Crepis crocea Babc.(C.turczaninowii C.A.Mey.)。[source] medical material Ji Yuan: for the root of the green stem Radix Crepidis elongatae of feverfew。Gather and store: summer, autumn gather, cleaning, dry。[nature and flavor] taste is micro-sweet;Bitter;Cool in nature。[return through] returns lung meridian, Liver Channel, kidney channel。[function cures mainly] heat clearing away;Cough-relieving;Dampness removing;Eliminating carbuncle。Main bronchus is scorching;Pneumonia;Hepatitis;Leucorrhea;Carbuncle furuncle。[usage and dosage] takes orally: decoct soup, 15~30g。[extracts] " China's book on Chinese herbal medicine "。
The Cornu Caprae seu Ovis torsion climing, little of Radix Gymnematis Sylvestris [another name] heartbroken hardship, lamb angle block, Radix Morindae Umbellatae, Rhizoma Smilacis Bockii, She Tianjiao, meal Wood-scoop rattan, Wu Yeteng, distension related to the heart Huang, spire Cornu Caprae seu Ovis are turned round。[source] medical material Ji Yuan: for root or the browse of dicotyledon Yao Luo section plant Largeleaf Gymnema。Gathering and store: root, the whole year all can adopt, and cleans, and section is dried or using fresh herb;Branch and leaf are gathered spring, using fresh herb。[nature and flavor] put down;Bitter。[return through] heart;Liver;Spleen channel。[function cures mainly] clearing away heat and cooling blood;Evacuation of pus is subsided a swelling;Pain relieving granulation promoting。Main air pain of dampness syndrome;Laryngopharynx swelling and pain;Scrofula;Acute mastitis;Furuncle;Eczema;Innominate toxic swelling;Venom。[usage and dosage] takes orally: decoct soup, 15~30g。[extracts] " China's book on Chinese herbal medicine "。
Lysimachia glaucina Franch [source] medical material Ji Yuan: for the herb of Ofthe Primulaceae Herba Tephrosiae purpureae Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis)。Gather and store: summer gathers, using fresh herb or dry。[nature and flavor] are pungent;Cool in nature。[return through] Liver Channel。[function cures mainly] rash。Main infantile measles is not saturating。[usage and dosage] takes orally: decoct soup, 3~10g。[extracts] " China's book on Chinese herbal medicine "。
Herba Ipomoeae Pes-Capraes [another name] king crab rattan, two leaf Radix Ipomoeae, lion rattan, Herba Dichodrae, Herba Calthae Membranaceae, sea potato, the Herba Blumeae Laciniatae, Ma Liuteng, Radix Clematidis terniflorae, sea potato rattan, Radix Stauntoniae chinensis, husky lampwick。[source] medical material Ji Yuan: for the herb of dicotyledon scammonia section plant king crab rattan。Gather and store: annual or summer, autumn seasonality are gathered, and remove impurity, cutting or sheet, dry。[nature and flavor] are pungent;Bitter;It is slightly cold。[return through] liver;Spleen channel。[function cures mainly] expelling wind and removing dampness;Eliminating carbuncle eliminating stagnation。Main air pain of dampness syndrome;Carbuncle;Furunculosis;Acute mastitis;Anal fistula。[usage and dosage] takes orally: decoct soup, 3~12g。Take passages] " China's book on Chinese herbal medicine "。
White butterfly is spent [another name] Radix Pecteilis susannae, gentle grass, soil Rhizoma Polygonati Odorati, ovum gallinaceum ginseng, cock flower, Radix Satyrii nepalensis, spends ginseng, pairing umbrella, Herba Microtis taiwanianae in vain。[source] medical material Ji Yuan: for the tuber that orchid tap is blue。Gather and store: autumn gathers, drying。[nature and flavor] sweet in the mouth;Slightly warm in nature。[function cures mainly] kidney invigorating and YANG supporting;Soothing the liver cold expelling。Main lumbago due to renal deficiency;Sexual impotence;Seminal emission;Colic of cold type。[usage and dosage] takes orally: decoct soup, 9~15g。[extracts] " China's book on Chinese herbal medicine "。
Semen Sapindi Delavayi [another name] bodhi pearl。[source] medical material Ji Yuan: for the fruits and seeds of Yunnan, sapindaceous plant river Fructus Sapindi Mukouossi。Gather and store: autumn fruit picking is real, using fresh herb or dry。[nature and flavor] are bitter;It is slightly cold。[return through] kidney;Bladder warp。[function cures mainly] circulation of qi promoting removing food stagnancy;Removing toxic substances parasite killing。Main hernia pain;Infantile malnutrition;Tonsillitis;Mumps;Mange;Impetigo;Ascariasis。[usage and dosage] takes orally: decoct soup, 6~15g。[extracts] " China's book on Chinese herbal medicine "。
Summary of the invention
It is desirable to provide a kind of Chinese medicine for treating erythema multiforme, by selecting suitable medical material and proportioning thereof, reach safely and effectively to cure the purpose of erythema multiforme。
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for treating erythema multiforme, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: Radix Polygoni Perfoliati 12 parts, Herba Alii fistulosi 15 parts, Radix Crepidis Ligneae 15 parts, Radix Gymnematis Sylvestris 10 parts, Lysimachia glaucina Franch 6 parts, Herba Ipomoeae Pes-Capraes 9 parts, white butterfly spend 12 parts, Semen Sapindi Delavayi 8 parts。
Below in conjunction with clinical laboratory data, beneficial effects of the present invention is described:
1, physical data
Inventor in October, 2012~2013 year collect outpatient service and erythema multiforme patient 60 example of being in hospital altogether between October, be randomly divided into treatment group 30 example and matched group 30 example, male 12 examples for the treatment of group, female 18 example, 20~70 years old age, 44.6 years old mean age;Matched group man's 13 examples, female 17 example, 19~70 years old age, 44.5 years old mean age。2 groups of sexes, age and course of disease comparing difference not statistically significant, have comparability。
Diagnostic criteria
Diagnostic criteria according to whole nation erythema multiforme clinical speciality meeting:
Symptom: erythema multiforme is pleomorphism with skin lesion, has erythema, pimple, vesicle, bulla, purpura, welt etc., with iris shape skin lesion for typical case's skin lesion。
Laboratory and other inspections: primary disease can be made a definite diagnosis according to skin lesion form and characteristic distributions, generally without special experimental laboratory and other inspection。Some skin lesion that is not true to type, when being with the naked eye difficult to differentiate, by means of histopathology and laboratory examination, but can only serve auxiliary diagnostic effect。
1) blood routine examination, when being typically in macule-papular type, the only typical performance of skin lesion, blood routine examination is without special change。When vesicle-bulla type and serious symptom type, numeration of leukocyte may be up to (10~20) × 109/L or more, and wherein neutrophilia and eosinophil leucocyte also can rise, particularly with high heat, during arthralgia, not only numeration of leukocyte rises, and erythrocyte sedimentation rate also can be had to accelerate。
2) routine urianlysis: when vesicle-bulla type and serious symptom type erythema multiforme, can have albumen in urine, very then may occur in which hematuria。
2, test method
2.1 Therapeutic Method
The capsule that the oral present invention specific embodiment 3 for the treatment of group prepares, every day 3 times。7 days courses for the treatment of。
Matched group is administered orally prednisone 10mg, every day 3 times, and after 3 days, decrement is l0mg, every day 2 times, 7 days courses for the treatment of。
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect
Cure: 1. skin lesion disappears completely, can leave pigmentation spots。2. no longer recur。
Effective: 1. skin lesion is whole or most disappears。2. even have slight recurrence。
Invalid: skin lesion part is without improving or increasing the weight of。
3.2 therapeutic outcomes are in Table 1。
1 liang of table group comparitive study
Visible, the medicine that the present invention prepares can safely and effectively treat erythema multiforme, has promotional value。
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment。
Embodiment 1
Weigh: Radix Polygoni Perfoliati 12 grams, Herba Alii fistulosi 15 grams, Radix Crepidis Ligneae 15 grams, Radix Gymnematis Sylvestris 10 grams, Lysimachia glaucina Franch 6 grams, Herba Ipomoeae Pes-Capraes 9 grams, white butterfly spend 12 grams, Semen Sapindi Delavayi 8 grams;Add 8 times amount water, decoct 1.5 hours, filter;Filtering residue adds 6 times amount water, decocts 1 hour, filters;Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of adult normal。
For treating erythema multiforme。Oral, every bu Morning Afternoon Evening is taken for three times。
Embodiment 2
Weigh: Radix Polygoni Perfoliati 12 grams, Herba Alii fistulosi 15 grams, Radix Crepidis Ligneae 15 grams, Radix Gymnematis Sylvestris 10 grams, Lysimachia glaucina Franch 6 grams, Herba Ipomoeae Pes-Capraes 9 grams, white butterfly spend 12 grams, Semen Sapindi Delavayi 8 grams;Add 10 times amount water, decoct 2 hours, filter;Filtering residue adds 8 times amount water, decocts 1.5 hours, filters;Merging filtrate, concentration, dry, packaging, the powder of one day consumption of adult normal must be met。
For treating erythema multiforme。Oral, every bu Morning Afternoon Evening is taken for three times。
Embodiment 3
Weigh: Radix Polygoni Perfoliati 12 grams, Herba Alii fistulosi 15 grams, Radix Crepidis Ligneae 15 grams, Radix Gymnematis Sylvestris 10 grams, Lysimachia glaucina Franch 6 grams, Herba Ipomoeae Pes-Capraes 9 grams, white butterfly spend 12 grams, Semen Sapindi Delavayi 8 grams;Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, concentration, dry, load capsule shells, the capsule of one day consumption of adult normal must be met。
For treating erythema multiforme。Oral, every bu Morning Afternoon Evening is taken for three times。

Claims (4)

1. the Chinese medicine being used for treating erythema multiforme, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: Radix Polygoni Perfoliati 12 parts, Herba Alii fistulosi 15 parts, Radix Crepidis Ligneae 15 parts, Radix Gymnematis Sylvestris 10 parts, Lysimachia glaucina Franch 6 parts, Herba Ipomoeae Pes-Capraes 9 parts, white butterfly spend 12 parts, Semen Sapindi Delavayi 8 parts。
2. the Chinese medicine for treating erythema multiforme as claimed in claim 1, it is characterized in that, its preparation method is: weigh: Radix Polygoni Perfoliati 12 parts, Herba Alii fistulosi 15 parts, Radix Crepidis Ligneae 15 parts, Radix Gymnematis Sylvestris 10 parts, Lysimachia glaucina Franch 6 parts, Herba Ipomoeae Pes-Capraes 9 parts, white butterfly spend 12 parts, Semen Sapindi Delavayi 8 parts;Add 8 times amount water, decoct 1.5 hours, filter;Filtering residue adds 6 times amount water, decocts 1 hour, filters;Merging filtrate, is concentrated into 120 parts, obtains decoct;Above-mentioned part each means weight portion。
3. the Chinese medicine for treating erythema multiforme as claimed in claim 1, it is characterized in that, its preparation method is: weigh: Radix Polygoni Perfoliati 12 parts, Herba Alii fistulosi 15 parts, Radix Crepidis Ligneae 15 parts, Radix Gymnematis Sylvestris 10 parts, Lysimachia glaucina Franch 6 parts, Herba Ipomoeae Pes-Capraes 9 parts, white butterfly spend 12 parts, Semen Sapindi Delavayi 8 parts;Add 10 times amount water, decoct 2 hours, filter;Filtering residue adds 8 times amount water, decocts 1.5 hours, filters;Merging filtrate, concentration, dry, packaging, obtain powder;Above-mentioned part each means weight portion。
4. the Chinese medicine for treating erythema multiforme as claimed in claim 1, it is characterized in that, its preparation method is: weigh: Radix Polygoni Perfoliati 12 parts, Herba Alii fistulosi 15 parts, Radix Crepidis Ligneae 15 parts, Radix Gymnematis Sylvestris 10 parts, Lysimachia glaucina Franch 6 parts, Herba Ipomoeae Pes-Capraes 9 parts, white butterfly spend 12 parts, Semen Sapindi Delavayi 8 parts;Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, concentration, dry, load capsule shells, obtain capsule;Above-mentioned part each means weight portion。
CN201610102314.1A 2016-02-24 2016-02-24 Traditional Chinese medicine for treating erythema multiforme Pending CN105687732A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106334064A (en) * 2016-09-30 2017-01-18 毛华养 Externally used medicament for erythema multiforme

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102370797A (en) * 2011-10-26 2012-03-14 文登市口腔医院 Traditional Chinese medicine for treating erythema multiforme
CN104248677A (en) * 2014-07-07 2014-12-31 贺珍 Traditional Chinese medicinal preparation for treating erythema multiforme
CN105168543A (en) * 2015-09-28 2015-12-23 成都倍加特生物科技有限公司 Decoction medicine for treating erythema multiforme and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102370797A (en) * 2011-10-26 2012-03-14 文登市口腔医院 Traditional Chinese medicine for treating erythema multiforme
CN104248677A (en) * 2014-07-07 2014-12-31 贺珍 Traditional Chinese medicinal preparation for treating erythema multiforme
CN105168543A (en) * 2015-09-28 2015-12-23 成都倍加特生物科技有限公司 Decoction medicine for treating erythema multiforme and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106334064A (en) * 2016-09-30 2017-01-18 毛华养 Externally used medicament for erythema multiforme

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Application publication date: 20160622