CN104127659A - Traditional Chinese medicine for treating chronic pharyngitis - Google Patents

Traditional Chinese medicine for treating chronic pharyngitis Download PDF

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Publication number
CN104127659A
CN104127659A CN201410420747.2A CN201410420747A CN104127659A CN 104127659 A CN104127659 A CN 104127659A CN 201410420747 A CN201410420747 A CN 201410420747A CN 104127659 A CN104127659 A CN 104127659A
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China
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parts
chinese medicine
herba
chronic pharyngitis
semen
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CN201410420747.2A
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Chinese (zh)
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高忠青
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Zibo Kuake Pharmaceutical Technology Co Ltd
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Zibo Kuake Pharmaceutical Technology Co Ltd
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Priority to CN201410420747.2A priority Critical patent/CN104127659A/en
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Abstract

The invention relates to a traditional Chinese medicine for treating chronic pharyngitis. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 8 parts of oroxylum indicum, 11 parts of laciniate kalanchoe herb, 23 parts of commelina hengalensis L., 9 parts of polygonum filiforme, 7 parts of stephania elegans, 12 parts of asparagus cochinchinensis and 1 part of entada phaseoloides. The clinical experiment proves that chronic pharyngitis can be safely and effectively treated by the traditional Chinese medicine.

Description

A kind of Chinese medicine that is used for the treatment of chronic pharyngitis
 
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine that is used for the treatment of chronic pharyngitis.
Background technology
Chronic pharyngitis is mainly thoroughly not cause repeatedly showing effect due to acute pharyngitis treatment, transfers to chronicly, or because suffer from various cacorhinias, nose key blocks, long-term mouth breathing, and physics, chemical factor, cervical region radiotherapy etc. often stimulate pharyngeal due to.The various chronic diseases of whole body, as anemia, constipation, lower respiratory tract chronic inflammatory disease, cardiovascular disease etc. also can secondary primary disease.Conscious pharyngeal discomfort, does, itches, swollen, and secretions is many and causalgia is easy to dry, has foreign body sensation, and not out, can not swallow, and above symptom is being spoken slightly manyly, after edible irritable food, when fatigue or Changes in weather, increases the weight of.Breathe and swallow all unblocked.Chronic pharyngitis belongs to the traditional Chinese medical science " chronic throat obstruction, chronic pharyngitis " category, its morbidity is many, and by virus, antibacterial repeated infection or in atmospheric pollution in recent years, serious, edible pungent taste is greasy increases and pharyngeal being subject to, pharyngeal mucosa, Submucosa and adenoid diffuse inflammation that the many factors such as various chemical factors stimulations cause.The sick position of primary disease is in pharynx, in close relations with lung spleen, and its pathological change is that mucosa is congested, Submucosa connective tissue and lymph foilicie hyperplasia.Treatment chronic pharyngitis focuses on heat-clearing and toxic substances removing, Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, clearing throat.
Medical material present Research involved in the present invention is as follows:
[source] medical material Ji Yuan such as Semen Oroxyli [another name] Semen Oroxyli, Semen Oroxyli, cutter tree of heap of stone, 300 liang of silver-colored medicines, Semen Oroxyli, cloud Semen Oroxyli: be the mature seed of Bignoniaceae plant Semen Oroxyli.The mature fruit of gathering in autumn, winter, tans by the sun to cracking of fruit, takes out seed, dries.[nature and flavor] mildly bitter flavor; Sweet; Cold nature.[return through] returns lung; Liver; Stomach is through the lung moistening of [function cures mainly] sore-throat relieving; Dispersing the stagnated liver-QI for regulating the stomach; Expelling pus and promoting granulation.Main pharyngalgia sore throat; Hoarseness; Cough; Stomachache due to hyperactive liver-QI attacking the stomach; Skin infection is burst and is not held back for a long time; Acute eczema.[usage and dosage] is for oral administration: decoct soup, 6-9g; Grind 1.5-3g into powder.External: appropriate, apply ointment or plaster; Or grind into powder and spread affected part.The herbal > > of [extracts] < < China
The blue or green back of the body of Herba Kalanchoes Laciniatae [another name] Radix Semiaquilegiae, Laciniate Kalanchoe Herb, five pawl Radix Notoginseng, false Rhizoma Coptidis [source] are the herb of crassulaceae plants Herba Kalanchoes Laciniatae.All can adopt the whole year, many using fresh herbs.[nature and flavor] are sweet; Bitter; Cold.[return through] heart; Liver; Lung meridian.The hemostasis of [function cures mainly] dissipating blood stasis; Heat-clearing and toxic substances removing.Main traumatic injury; Sprain; Traumatic hemorrhage; Pharyngolaryngitis; Scald; Eczema; Carbuncle pyogenic infections from tumour or sore; Venom.[usage and dosage] is for oral administration: decoct soup, 10-15g.External: appropriate, smash deposited; Or smash juice and be coated with.The herbal > > of [extracts] < < China
Horse Auricled Hedyotis Herb [another name] bamboo dish, the young dish of bamboo, bamboo bamboo dish, Herba Commelinae Bengalensis, match end, thousand Exposures to Sunlight [source] are the herb of Commelianaceae plant meal bag grass.[nature and flavor] hardship; Cold.[function cures mainly] heat-clearing and toxic substances removing; Inducing diuresis to remove edema.Main calentura heating; Excessive thirst; Laryngopharynx swelling and pain; Hematodiarrhoea; Pyretic stranguria; Hemorrhoid; Furuncle carbuncle; Snake bite and insect sting.[usage and dosage] is for oral administration: decoct soup, 15-30g, fresh goods 30-60g.External: appropriate, fresh goods is smash deposited; Or decoct washing.The herbal > > of [extracts] < < China
Herba Tripterospermi [another name] is worn rattan Cephalanthera falcata (Thunb) Lindl flower, Semen Oroxyli, Polygonum runcinatum Buch.Ham, iron plate is blue or green, four feet are liked, mountain butterfly [source] is the tender herb of children of gentianaceae plant Tripterospermum affine.Summer, autumn gather, and dry or using fresh herb.[nature and flavor] are pungent, sweet, bitter, property.[function cures mainly] clearing away lung-heat to relieve cough; Cooling blood for hemostasis; Diuresis removing toxic substances.Main cough due to lung-heat; Pulmonary tuberculosis spitting of blood; Lung abscess; Nephritis; Acute mastitis; Carbuncle sore furuncle is swollen; Wound hemorrhage; Venom.[usage and dosage] is for oral administration: decoct soup, 9~15g, fresh goods 30~60g.External: appropriate, fresh goods is smash deposited; Or grind into powder and spread.The herbal > > of [extracts] < < China
The graceful Radix Stephaniae Japonicae of Artline Radix Stephaniae Japonicae [another name], Radix Sophorae Tonkinensis, little Radix Sophorae Tonkinensis, Radix Stephaniae Japonicae.[source] is the root of menispermaceous plants Artline Radix Stephaniae Japonicae.All can excavate the whole year, removes fibrous root, cleans, and dries.[habitats distribution] is distributed in From Western Yunnan.[nature and flavor] are pungent; Bitter; Cold.[function cures mainly] heat-clearing and toxic substances removing; Wind-expelling pain-stopping.Main laryngopharynx swelling and pain; Sore; Hemorrhoid are swollen; Rheumatic arthralgia.[usage and dosage] is for oral administration: decoct soup, 3-9g.The herbal > > of [extracts] < < China
Radix Asparagi [another name] the Men winter, greatly when a door root, Radix Asparagi [source] they are the tuber of liliaceous plant Radix Asparagi.After field planting, 2-3 can gather, and prescinds viticula, and lifted root removes earth, with decocting in water or steam to rhagades of the skin, pulls out in clear water, peels off while hot crust, dries or stifling with sulfur.[nature and flavor] sweet in the mouth; Bitter; Cold in nature.[return through] lung; Kidney channel.[function cures mainly] is nourshing Yin and drynsessmoistening prescription; Lung heat clearing pathogenic fire reducing.Main cough caused by dryness-heat; Deficiency of YIN chronic cough; Consumption of YIN caused by febrile disease; Interior-heat is quenched one's thirst; Dryness of the intestine constipation; Laryngopharynx swelling and pain.[usage and dosage] is for oral administration: decoct soup, 6-15g; Endure cream, or enter ball, loose.External: appropriate, fresh goods is smash and applied or mash the painting of strand juice.The herbal > > of [extracts] < < China
Semen Entadae [another name] resembles the seed that bean, zygote, Ke, glasses bean [source] this product Wei Dou section are planted thing Semen Entadae.Winter, spring gather after seed maturity, and decapsidate, dries.[nature and flavor] are puckery sweet; Flat; Nontoxic.[return through] stomach; Liver; Large intestine channel.[function cures mainly] promoting the circulation of QI to relieve pain, inducing diuresis and reducing edema.Main abdominal distention, jaundice, beriberi edema, dysentery, hemorrhoid, proctoptosis, sore throat.[usage and dosage] is for oral administration: charred medicinal herb with its property retained is ground into powder, 1-3g; Or decoction.External: appropriate, smash to apply or grind into powder and dress.The herbal > > of [extracts] < < China.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of chronic pharyngitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic pharyngitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine that is used for the treatment of chronic pharyngitis, it is characterized in that, it is that raw medicinal material by following weight proportion is prepared from: 8 parts of Semen Oroxylis, 11 parts of Herba Kalanchoes Laciniataes, 23 parts of horse Auricled Hedyotis Herbs, 9 parts of Herba Tripterospermis, 7 parts of Artline Radix Stephaniae Japonicaes, 1 part of Radix Asparagi 12 Fen, Semen Entadae.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects patients with chronic pharyngitis 104 examples in JIUYUE, 2011-2014 altogether between year April, all meet chronic pharyngitis diagnostic criteria.Treatment group 52 examples, male 31 examples, female's 21 examples, age 34.24 ± 11.29; Matched group 52 examples, male 32 examples, female's 20 examples, age 37.98 ± 15.77.Two groups of Genders, age ratio, p> 0.05 difference not statistically significant, has comparability.
2, test method
2.1 tcm diagnosis standards
The dry pain of throat, scorching hot, after polylogia, symptom increases the weight of, and chokes and coughs without expectorant, or have a small amount of sticky expectorant, again and again ask drink, drink amount is few, and during afternoon and dusk, symptom is obvious, and pharyngeal congestion is kermesinus, mucosa is dry, atrophy, or has lymph foilicie hyperplasia, and red tongue with thin fur is few, thready and rapid pulse.
2.2 case inclusion criteria and exclusion standards
Inclusion criteria: 1. all be diagnosed as chronic pharyngitis and meet Chinese medical discrimination belong to syndrome of flaring up of deficient fire person can include test case in; 2. the age is in 18-65 year.
Exclusion standard: 1. confirm on inspection by person due to some invisible pathological changes of oropharynx, nasopharynx, throat, nose, larynx, esophagus, cervical region and whole body; 2. gestation or women breast-feeding their children, those who are allergic to this drug; 3. be associated with the serious primary disease such as cardiovascular, liver, kidney, hemopoietic system, psychotic; Though be 4. primary disease, long-term taking Western medicine or other medicines person, must stop using more than 2 weeks, otherwise should get rid of.
2.3 Therapeutic Method
The decoct that the oral the present invention for the treatment of group makes according to specific embodiment 1, every day 3 times.14 days courses for the treatment of.
Matched group oral administered compound Herba Pileae Scriptae Tabellae, is used 14 days courses for the treatment of according to its description.
2.4 observation index
The untoward reaction that 1. may occur clinically;
2. blood, urine routine test, electrocardiogram and liver (blood ALT), kidney (blood BUN) functional check;
3. health giving quality observation: symptom is with pharyngeal sense of discomfort growth and decline situation of change; Pharyngeal sign is with the variation of the performances such as the hyperemia of pharyngeal mucosa, edema, plumpness, dry, atrophy; The enlargement situation of pharyngeal lymphoid tissue (comprising palate tonsil, retropharyngeal lymph nodes, lateral pharyngeal band etc.) and cervical lymph node;
4. syndrome observation.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
3.1.1 chronic pharyngitis comprehensive therapeutic effect:
1. effective: in medication 2 weeks, clinical symptoms and sign are most of to disappear;
2. effective: in medication 2 weeks, clinical symptoms and sign partly disappear;
3. invalid: after medication, symptom slightly alleviates or without alleviating, sign is not improved.
Total effective rate=(effective+effectively)/total number of cases * 100%
3.1.2 the disease standards of grading of traditional Chinese medical science hyperactivity of deficient fire disease
Each individual event syndrome (hyperemia of pharyngeal sense of discomfort growth and decline situation of change, pharyngeal mucosa, edema,
The enlargement situation of plump, dry, atrophy, palate tonsil, retropharyngeal lymph nodes, lateral pharyngeal band and cervical lymph node) by light, in, heavily comment 1,2,3 minute, do nothing 0 minute, its cumulative point is integration.
3.2 therapeutic outcome
The Comprehensive Clinical curative effect of two groups of treatments is in Table 1.
Table 1 liang group Clinical efficacy comparison
Group n Effective Effectively Invalid Total effective rate
Treatment group 52 23 24 5 90.4%
Matched group 52 17 23 12 76.9%
Data in table are analyzed through Ridit, and the curative effect for the treatment of group is better than matched group, p< 0.01.Test group 52 examples, effective 23 examples (44.2%), effective 24 examples (46.2%), invalid 5 examples (9.6%), total effective rate 90.4%.
Before and after table 2 liang group treatment, the scoring of traditional Chinese medical science disease relatively
Group n Before treatment After treatment Minimizing amplitude
Treatment group 52 27.6±6.9 9.5±4.8 18.1±5.3
Matched group 52 26.3±5.3 16.4±5.1 9.9±6.4
By treatment group before table 2 data analysis treatment similar to the integration of matched group ( p> 0.05); Treatment after treatment group integration than matched group few ( p< 0.05); The amplitude treatment group that integration reduces than matched group large ( p< 0. 01).
3.3 untoward reaction and routine test
Two groups have no untoward reaction clinically, and the detections such as treatment front and back routine blood test, routine urinalysis, blood ALT, blood BUN and electrocardiogram have no abnormal changes.It is high that visible the present invention is used for the treatment of chronic pharyngitis cure rate, has the value of applying.
The specific embodiment
In order to understand better and to implement the present invention, below in conjunction with specific embodiment, further illustrate the present invention.
Specific embodiment 1
Take: 8 grams of Semen Oroxylis, 11 grams of Herba Kalanchoes Laciniataes, 23 grams of horse Auricled Hedyotis Herbs, 9 grams of Herba Tripterospermis, 7 grams of Artline Radix Stephaniae Japonicaes, 1 gram of Radix Asparagi 12 Ke, Semen Entadae; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of normal adult.
Be used for the treatment of chronic pharyngitis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: 8 grams of Semen Oroxylis, 11 grams of Herba Kalanchoes Laciniataes, 23 grams of horse Auricled Hedyotis Herbs, 9 grams of Herba Tripterospermis, 7 grams of Artline Radix Stephaniae Japonicaes, 1 gram of Radix Asparagi 12 Ke, Semen Entadae; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of chronic pharyngitis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 3
Take: 8 grams of Semen Oroxylis, 11 grams of Herba Kalanchoes Laciniataes, 23 grams of horse Auricled Hedyotis Herbs, 9 grams of Herba Tripterospermis, 7 grams of Artline Radix Stephaniae Japonicaes, 1 gram of Radix Asparagi 12 Ke, Semen Entadae; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, must meet the capsule of one day consumption of normal adult.
Be used for the treatment of chronic pharyngitis.Oral, every bu morning, noon and afternoon take for three times.

Claims (4)

1. a Chinese medicine that is used for the treatment of chronic pharyngitis, it is characterized in that, it is that raw medicinal material by following weight proportion is prepared from: 8 parts of Semen Oroxylis, 11 parts of Herba Kalanchoes Laciniataes, 23 parts of horse Auricled Hedyotis Herbs, 9 parts of Herba Tripterospermis, 7 parts of Artline Radix Stephaniae Japonicaes, 1 part of Radix Asparagi 12 Fen, Semen Entadae.
2. the Chinese medicine that is used for the treatment of chronic pharyngitis as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Semen Oroxylis, 11 parts of Herba Kalanchoes Laciniataes, 23 parts of horse Auricled Hedyotis Herbs, 9 parts of Herba Tripterospermis, 7 parts of Artline Radix Stephaniae Japonicaes, 1 part of Radix Asparagi 12 Fen, Semen Entadae; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. the Chinese medicine that is used for the treatment of chronic pharyngitis as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Semen Oroxylis, 11 parts of Herba Kalanchoes Laciniataes, 23 parts of horse Auricled Hedyotis Herbs, 9 parts of Herba Tripterospermis, 7 parts of Artline Radix Stephaniae Japonicaes, 1 part of Radix Asparagi 12 Fen, Semen Entadae; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packing, obtains powder; Above-mentioned part all refers to weight portion.
4. the Chinese medicine that is used for the treatment of chronic pharyngitis as claimed in claim 1, is characterized in that, its preparation method is: take: 8 parts of Semen Oroxylis, 11 parts of Herba Kalanchoes Laciniataes, 23 parts of horse Auricled Hedyotis Herbs, 9 parts of Herba Tripterospermis, 7 parts of Artline Radix Stephaniae Japonicaes, 1 part of Radix Asparagi 12 Fen, Semen Entadae; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, obtain capsule; Above-mentioned part all refers to weight portion.
CN201410420747.2A 2014-08-26 2014-08-26 Traditional Chinese medicine for treating chronic pharyngitis Pending CN104127659A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104586935A (en) * 2015-02-13 2015-05-06 淄博夸克医药技术有限公司 Traditional Chinese medicine for treating chronic pharyngitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1631425A (en) * 2004-12-02 2005-06-29 李佩服 Lozenge for treating its pharyngitis and preparation process thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1631425A (en) * 2004-12-02 2005-06-29 李佩服 Lozenge for treating its pharyngitis and preparation process thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104586935A (en) * 2015-02-13 2015-05-06 淄博夸克医药技术有限公司 Traditional Chinese medicine for treating chronic pharyngitis

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