CN105477564A - Traditional Chinese medicine composition for treating prosopalgia - Google Patents

Traditional Chinese medicine composition for treating prosopalgia Download PDF

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Publication number
CN105477564A
CN105477564A CN201610049700.9A CN201610049700A CN105477564A CN 105477564 A CN105477564 A CN 105477564A CN 201610049700 A CN201610049700 A CN 201610049700A CN 105477564 A CN105477564 A CN 105477564A
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pain
chinese medicine
medicine composition
traditional chinese
fici pumilae
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刘明
章峰
肖传敏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/83Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

Provided is a traditional Chinese medicine composition for treating prosopalgia. The composition is prepared from Scheffter leacantha Vig.[Schef-flera kwangsiensis Merr.ex Li], daphne odora flowers, ficus pumila, Ixora chinensis Lam., curcuma, tangerine seeds, Hamate Calanthe, rhizoma curcumae longae, bauhinia seeds, anise and liquorice roots. The traditional Chinese medicine composition can be clinically used for treating prosopalgia.

Description

One treats prosopalgic Chinese medicine composition
This case is divisional application, original applying number: 201410140862.4; Original application day: on 04 10th, 2014; Former denomination of invention: one treats prosopalgic Chinese medicine.
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to one and treat prosopalgic Chinese medicine composition.
Background technology
Primary trigeminal neuralgia system a kind of periodicity, paroxysmal, violent and insufferable pain, pain often presents electric shock, acupuncture, lancinates or burn sample, and the general several seconds is to stopping suddenly after several minutes.There is trigger point responsive especially nervi trigeminus areal area, and it is one or more that pain is usually confined to one-sided nervi trigeminus.In the past comparatively conventional clinically method has: Drug therapy, alinjection and operative treatment.Operative treatment comprises: peripheral branch Avulsion, amputation and spinal tract of trigeminal nerve amputation.But most of patients is difficult to be treated surgically.After recurrence, therapeutic effect is how not good.Additive method is as treatments such as medicine carbamazepine, alinjections, and wherein carbamazepine is the prosopalgic first-selection of Drug therapy, but also because side effect is large or risk is higher, patient is difficult to accept.The traditional Chinese medicine composition for treating trigeminal neuralgia that the present invention prepares, achieves good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, to the prosopalgic Chinese medicine composition of the treatment of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts and spend schefflera in vain, Flos daphnes odorae, Caulis fici pumilae (Fructus Fici Pumilae), Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Radix Curcumae, Fructus Citri tangerinae core, four is stupefied logical, Rhizoma Curcumae Longae, Semen Bauhiniae championii, anistree, Radix Glycyrrhizae, according to certain compatibility requirement, through being processed into.
Prepare Chinese medicine composition of the present invention to be made up of following raw material medicaments: spend schefflera 50-70 part in vain, Flos daphnes odorae 30-40 part, Caulis fici pumilae (Fructus Fici Pumilae) 30-40 part, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 20-30 part, Radix Curcumae 20-30 part, Fructus Citri tangerinae core 20-30 part, four stupefied logical 15-20 parts, Rhizoma Curcumae Longae 15-20 part, Semen Bauhiniae championii 15-20 part, anistree 6-10 part, Radix Glycyrrhizae 6-10 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: spend schefflera 60 parts in vain, Flos daphnes odorae 35 parts, Caulis fici pumilae (Fructus Fici Pumilae) 35 parts, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 25 parts, Radix Curcumae 25 parts, Fructus Citri tangerinae core 25 parts, four stupefied logical 18 parts, 18 parts, Rhizoma Curcumae Longae, Semen Bauhiniae championii 18 parts, anistree 8 parts, 8 parts, Radix Glycyrrhizae.
The pharmacological action of Chinese medicine composition of the present invention is as follows:
Spend schefflera in vain: micro-hardship, puckery, warm.Wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral.For rheumatic arthralgia, sciatica, migraine and general headache, trigeminal neuralgia, the diseases such as dysmenorrhea.
Flos daphnes odorae: sweet, pungent, flat.Return lung, stomach, Liver Channel.Promoting blood circulation and stopping pain, detoxicating and resolving stagnation of pathogens.Clinical in headache, toothache, laryngopharynx swelling and pain, rheumatalgia, breast is swollen hard, the diseases such as rheumatalgia.
Caulis fici pumilae (Fructus Fici Pumilae): sour, cool.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances and promoting subsidence of swelling.Clinical in rheumatic arthralgia, sciatica, dysentery, urine drenches, edema, malaria, amenorrhea, and postnatal blood stasis is suffered from abdominal pain, laryngopharynx swelling and pain, orchitis, dermatitis rhus, pain pyogenic infections from tumour or sore, the diseases such as traumatic injury.
Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati): sweet, light, cool.Return Liver Channel.Clearing away heat and cooling blood, eliminating stasis to stop pain.For hypertension, menoxenia, amenorrhea, traumatic injury, skin infection furuncle and phyma etc.
Radix Curcumae: bitter, acrid, cold, returns liver, gallbladder, heart channel.Blood-activating and qi-promoting pain relieving, resolving depression clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood.For the card of calentura coma, epilepsy unconsciousness due to blockage of phlegm.
Fructus Citri tangerinae core: flat, bitter, returns liver, kidney channel.Regulate the flow of vital energy, eliminating stagnation, pain relieving.For inguinal hernia, painful and swollen testis, acute mastitis swells and ache.
Four is stupefied logical: puckery, sweet, be slightly cold.Dispelling wind and removing obstruction in the collateral, suppressing the hyperactive liver to relieve the wind syndrome.Clinical in rheumatic arthritis, sciatica, traumatic injury, fracture, traumatic hemorrhage, hypertension, migraine, infantile convulsion, the diseases such as proctoptosis.
Rhizoma Curcumae Longae: bitter in the mouth, pungent, warm in nature.Return spleen, Liver Channel.Removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.The all cards of stagnation of QI and blood, born of the same parents' abdomen hypochondriac pain, dysmenorrhes, the stagnant stomachache of the stasis of blood in puerperal, rheumatic arthralgia, traumatic injury, carbuncle etc.
Semen Bauhiniae championii: bitter, Xin Wen.Return liver, stomach warp.For the seed of leguminous plant Caulis Bauhihiae Championii.Promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling.For stagnation of QI and blood, distending pain over the hypochondrium, gastric abscess, traumatic injury.
Anistree: pungent, sweet, warm.Return liver,kidney,spleen, stomach warp.Cold expelling, regulate the flow of vital energy, pain relieving.For colic of cold type stomachache, the vomiting of chills and pain of the waist and kness, fear of cold, the disturbance of lower legs due to pathogenic cold and dampness etc.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.For severe palpitation, the irregularly intermittent and regularly intermittent pulse of deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.
Primary disease belongs to the traditional Chinese medical science " headache " card category.Motherland's medical science is thought " general rule not bitterly, stagnation of QI and blood may bring about pain ".Its etiology and pathogenesis is because ailment said due to cold or exposure enters middle women's head-ornaments meridians, and the turbid mutual knot of expectorant in body, day lingering arthralgia resistance channels, and qi and blood circulation is smooth, stagnation of QI and blood may bring about pain and cause this and sickly to occur, so method is when dispelling pathogenic wind and eliminating phlegm, promoting blood circulation to remove obstruction in the collateral, relieving spasm to stop pain.The present invention spends schefflera wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral in vain, is monarch drug, Flos daphnes odorae promoting blood circulation and stopping pain, detoxicating and resolving stagnation of pathogens, and Caulis fici pumilae (Fructus Fici Pumilae) dispels the wind, promoting blood circulation to remove obstruction in the collateral, removing toxic substances and promoting subsidence of swelling, is ministerial drug; Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) eliminating stasis to stop pain, the pain relieving of Radix Curcumae blood-activating and qi-promoting, Fructus Citri tangerinae core is regulated the flow of vital energy, eliminating stagnation, pain relieving, four stupefied logical dispelling wind and removing obstruction in the collateral, Rhizoma Curcumae Longae promoting the circulation of QI to relieve pain, Semen Bauhiniae championii promoting the circulation of QI to relieve pain, invigorate blood circulation, anistree regulating QI to relieve pain, Radix Glycyrrhizae blood-activating and qi-promoting, pain relieving, liver and kidney tonifying.All medicines share, and play the merit of wind-expelling pain-stopping, promoting blood circulation to remove obstruction in the collateral, circulation of qi promoting removing toxic substances altogether, reach the prosopalgic object for the treatment of.
Chinese medicine composition of the present invention is used in 2009 to 2013 the routine patients of clinical observation trigeminal neuralgia disease 55, and clinical report is as follows:
1, physical data
In 55 routine patients, women 25 example, male 30 example, at minimum 45 years old of age, maximum 77 years old, the course of disease was many at 2 months to 5 years, 53 years old mean age.
2, diagnostic criteria
With reference to " internal disease diagnostic criteria ":
Ictal pain within face and forehead last for several seconds to 2min; pain has following 4 features: pain is positioned at the distribution of nervi trigeminus more than 1 or 1; pain has suddenly, violent, show shallow, lancinate sample or burn the character of sample; by toggle area; or caused as taken food, speaking, wash one's face, brush teeth by some daily routines; completely normal twice interictal patient; during panic attacks; conjunctival congestion; shed tears, facial flushes, sialorrhea; the cause visible face spasm of pain repeatedly, does not have neural any defect finding.
3, Therapeutic Method
3.1 prescriptions: spend schefflera 60g in vain, Flos daphnes odorae 35g, Caulis fici pumilae (Fructus Fici Pumilae) 35g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 25g, Radix Curcumae 25g, Fructus Citri tangerinae core 25g, four stupefied logical 18g, Rhizoma Curcumae Longae 18g, Semen Bauhiniae championii 18g, anistree 8g, Radix Glycyrrhizae 8g.
3.2 preparation methoies: said medicine routinely technique makes decoction.
3.3 instructions of taking: each 1 dose, every day 2 times 30 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 with reference to " Chinese medical disease Standardization of diagnosis and curative effect ":
Cure: after treatment, pain disappears, and follows up a case by regular visits to and does not recur half a year;
Effective: after medication, pain disappears, and follow up a case by regular visits in half a year and have recurrence (> 3 months), then medication is still effective;
Effective: remission after medication, but recurrence in 1-2 month;
Do not heal: symptom is without obvious change.
4.2 results: in 55 routine patients, cure 25 examples (45.5%), effective 18 examples (32.7%), effective 7 examples (12.7%), and do not heal 5 examples (9.1%), and total effective rate is 90.9%.
5, model case
5.1 grandsons, man, 66 years old.Readme trigeminal neuralgia 3 years, can trigger trigeminal neuralgia when touching facial or excited.On the right side of during outbreak, buccal, lower jaw are as lightning sample pain, have a strong impact on daily life.Once took carbamazepine, originally pain can be alleviated, rear poor effect, red tongue with thin and yellow fur, and there is petechia on tongue limit, deep and stringy pulse.Take the present invention to treat prosopalgic Chinese medicine composition and treat, after treating 2 courses for the treatment of, pain degree, number of times all alleviate, and continue to take 1 course for the treatment of, and recovery from illness, follows up a case by regular visits to half a year and do not show effect.
5.2 Liu, female, 52 years old, left side gingiva, buccal pain, the traction brilliance, recurrent exerbation, gesture was as acupuncture of lancinating, and endlessly, the micro-fiber crops of lip cheek car lower jaw part, buccal flushing, sialorrhea of shedding tears, even mild wind strokes face, can inspire paroxysmal pain in groan.Taken the present invention and treated prosopalgic Chinese medicine composition, 1 course for the treatment of, pain degree, number of times all alleviate, and continue to take 1 course for the treatment of, and recovery from illness, follows up a case by regular visits to half a year and do not show effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, one treats prosopalgic Chinese medicine composition, and it is made up of following raw material medicaments: spend schefflera 50g in vain, Flos daphnes odorae 30g, Caulis fici pumilae (Fructus Fici Pumilae) 30g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 20g, Radix Curcumae 20g, Fructus Citri tangerinae core 20g, four stupefied logical 15g, Rhizoma Curcumae Longae 15g, Semen Bauhiniae championii 15g, anistree 6g, Radix Glycyrrhizae 6g.
Embodiment 2, one treats prosopalgic Chinese medicine composition, and it is made up of following raw material medicaments: spend schefflera 60g in vain, Flos daphnes odorae 35g, Caulis fici pumilae (Fructus Fici Pumilae) 35g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 25g, Radix Curcumae 25g, Fructus Citri tangerinae core 25g, four stupefied logical 18g, Rhizoma Curcumae Longae 18g, Semen Bauhiniae championii 18g, anistree 8g, Radix Glycyrrhizae 8g.
Embodiment 3, one treats prosopalgic Chinese medicine composition, and it is made up of following raw material medicaments: spend schefflera 70g in vain, Flos daphnes odorae 40g, Caulis fici pumilae (Fructus Fici Pumilae) 40g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 30g, Radix Curcumae 30g, Fructus Citri tangerinae core 30g, four stupefied logical 20g, Rhizoma Curcumae Longae 20g, Semen Bauhiniae championii 20g, anistree 10g, Radix Glycyrrhizae 10g.

Claims (1)

1. treat a prosopalgic Chinese medicine composition, it is characterized in that crude drug is:
Spend schefflera 50g in vain, Flos daphnes odorae 30g, Caulis fici pumilae (Fructus Fici Pumilae) 30g, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati) 20g, Radix Curcumae 20g, Fructus Citri tangerinae core 20g, four stupefied logical 15g, Rhizoma Curcumae Longae 15g, Semen Bauhiniae championii 15g, anistree 6g, Radix Glycyrrhizae 6g.
CN201610049700.9A 2014-04-10 2014-04-10 Traditional Chinese medicine composition for treating prosopalgia Withdrawn CN105477564A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498753A (en) * 2017-05-23 2018-09-07 苏州富欧生物科技有限公司 A kind of Chinese medicine preparation for treating trigeminal neuralgia

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Publication number Priority date Publication date Assignee Title
CN104399004A (en) * 2014-12-11 2015-03-11 青岛市市立医院 Traditional Chinese medicine formula for treating prosopalgia
CN104491732A (en) * 2014-12-26 2015-04-08 陈蔚峰 Traditional Chinese medicine formula for treating craniocerebral injury or intracranial tumor postoperative neuralgia
CN104623193A (en) * 2015-01-09 2015-05-20 青岛市中心医院 Traditional Chinese medicine formula for treating prosopalgia
CN104815203A (en) * 2015-04-20 2015-08-05 韩萍 Traditional Chinese medicine prescription for treating prosopalgia
CN106139043A (en) * 2016-09-22 2016-11-23 耿燕娜 A kind of Neurology Department treats prosopalgic medicine

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CN102961450A (en) * 2012-11-30 2013-03-13 刘静 Traditional Chinese medicine composition for treating prosopalgia
CN103463344A (en) * 2013-08-20 2013-12-25 田家浩 Traditional Chinese medicinal composition for treating trigeminal neuralgia

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CN1046093C (en) * 1994-04-05 1999-11-03 戚嘉和 Traditional Chinese medicinal prepn. for treating trifacial neuralgia

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Publication number Priority date Publication date Assignee Title
CN102961450A (en) * 2012-11-30 2013-03-13 刘静 Traditional Chinese medicine composition for treating prosopalgia
CN103463344A (en) * 2013-08-20 2013-12-25 田家浩 Traditional Chinese medicinal composition for treating trigeminal neuralgia

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108498753A (en) * 2017-05-23 2018-09-07 苏州富欧生物科技有限公司 A kind of Chinese medicine preparation for treating trigeminal neuralgia

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Application publication date: 20160413