CN102198202A - Pills for treating gout - Google Patents
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- CN102198202A CN102198202A CN2011101156422A CN201110115642A CN102198202A CN 102198202 A CN102198202 A CN 102198202A CN 2011101156422 A CN2011101156422 A CN 2011101156422A CN 201110115642 A CN201110115642 A CN 201110115642A CN 102198202 A CN102198202 A CN 102198202A
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Abstract
The invention discloses a Chinese medicine for treating gout, namely pills for treating gout. The formula of the pills for treating gout comprises: 10 to 20 weight parts of prepared monkshood, 10 to 20 weight parts of prepared radix aconiti agrestis, 10 to 20 weight parts of safflower, 10 to 20 weight parts of rhizoma acori graminei, 10 to 20 weight parts of black soyabean, 10 to 20 weight parts of szechuan pepper, 10 to 20 weight parts of lycopodium clavatum, 8 to 12 weight parts of notopterygium root, 8 to 12 weight parts of radix angelicae pubescentis, 8 to 12 weight parts of cassia twig, 8 to 12 weight parts of white paeony root, 8 to 12 weight parts of cinnamon, 8 to 12 weight parts of fried liquoric root. Besides the above main ingredients, the formula also comprises an acaciahoney auxiliary ingredient. By taking the pills for treating gout, the effects of warning channels, activating yang, sweating, expelling pathogenic factors from muscles and skin, balancing energy and qi, warming limbs, inducing diaphoresis to dispel cold, relieving pain in limbs, reliving pain, unblocking channels, expelling internal cold and pathogen, removing Yin pathogen, soothing mind, depressing upward invasion qi, lowering counterflow, keeping healthy qi in position, depressing and defusing mephitis, and discharging toxic matters from sweat or urine and feces are achieved. By regulating the five organs and six hollow organs, the Chinese medicine can treat gout from root, the treatment period is short, the cost is low, the toxic and side effect are light and the treatment effect is desirable.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of gout, belong to pure Chinese herbal medicine.
Background technology
Gout claims " hyperuricemia " again, and the purine metabolism obstacle belongs to arthritic a kind of.Gout is that the metabolism of the material of purine in the human body gets muddled, and the synthetic increase of uric acid or discharge reduce, and cause hyperuricemia, during the blood uric acid excessive concentration, uric acid is deposited in joint, cartilage and the kidney with the form of sodium salt, causes to organize foreign body inflammatory reaction, i.e. gout.The gout that modern medicine is said also is equivalent to diseases such as the traditional Chinese medical science " arthralgia aggravated by cold ", " severe and migratory arthralgia ", " beriberi ".Western medical treatment does not have effect method at present, and medication has bigger toxic and side effects, the cost height.Though other traditional Chinese medical science medicine can be obtained certain curative effect, there is the unsafty defective of therapeutic effect.
Summary of the invention
Technical problem to be solved by this invention is, a kind of Chinese medicine for the treatment of gout is provided, by expelling cold and relieving exterior syndrome, and making the adverse-rising QI downwards, easypro contraction relieves the pain, and fundamentally treats gout, to overcome the defective of existing such disease medicine of treatment.
It is as follows that the present invention solves the problems of the technologies described above the technical scheme that is adopted:
A kind of Chinese medicine for the treatment of gout is characterized in that its prescription is: Radix Aconiti Preparata 10-20 part, Radix Aconiti Kusnezoffii Preparata 10-20 part, Flos Carthami 10-20 part, Rhizoma Acori Graminei 10-20 part, Semen sojae atricolor 10-20 part, river MAJIAO 10-20 part, Herba Lycopodii 10-20 part, Rhizoma Et Radix Notopterygii 8-12 part, Radix Angelicae Pubescentis 8-12, Ramulus Cinnamomi 8-12 part, Radix Paeoniae Alba 8-12 part, Cortex Cinnamomi 8-12 part, Radix Glycyrrhizae Preparata 8-12 part; Described part all refers to weight portion.
Preferred prescription is: 15 parts of Radix Aconiti Preparatas, 15 parts of Radix Aconiti Kusnezoffii Preparatas, 15 parts on Flos Carthami, 15 parts of Rhizoma Acori Graminei, 15 parts of Semen sojae atricolor, 15 parts of river MAJIAO, 15 parts of Herba Lycopodiis, 10 parts of Rhizoma Et Radix Notopterygiis, Radix Angelicae Pubescentis 10,10 parts of Ramulus Cinnamomi, 10 parts of the Radix Paeoniae Albas, 10 parts of Cortex Cinnamomis, 10 parts of Radix Glycyrrhizae Preparata.
The main Chinese herbal medicine of prescription of the present invention is according to traditional medicine and modern medicine analysis, and the property of medicine and pharmacological action are as follows:
Radix Aconiti Preparata: meridian distribution of property and flavor: heat; Hot, bitter; GUIXIN, spleen, liver, kidney channel; Big poison.Function cures mainly: expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Radix Aconiti Kusnezoffii Preparata: meridian distribution of property and flavor: heat; Hot, bitter; GUIXIN, liver,kidney,spleen warp; Big poison.Function cures mainly: expelling wind and removing dampness, antalgic.Be used for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Flos Carthami: meridian distribution of property and flavor: temperature; Hot; GUIXIN, Liver Channel.Function cures mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.Be used for amenorrhea, dysmenorrhea, lochia is not all right, purplish or white patches on the skin abdominal mass mass in the abdomen, injury from falling down, skin infection swells and ache.
Rhizoma Acori Graminei: meridian distribution of property and flavor: temperature; Hot, bitter; GUIXIN, stomach warp.Function cures mainly: removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.It is not hungry to be used for the wrist painful abdominal mass, mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.
Semen sojae atricolor: Semen sojae atricolor is flat, sweet in the mouth; Return spleen, kidney channel; Have that the detumescence therapeutic method to keep the adverse QI flowing downwards, lung moistening are scorching, activating blood and promoting diuresis, the eliminating impediment that dispels the wind, blood-enriching tranquillizing, the spleen invigorating that makes eye bright, the kidney invigorating tonifying YIN, antidotal effect; Be used for that edema distension, pathogenic wind-toxic beriberi, jaundice edema, migratory arthralgia spasm, puerperal exposure to wind are painful, locked mouth, carbuncle sore tumefacting virus, can separate poison of drug, system wind heat and end night sweat, the function of black hair hair color and life lengthening.
River MAJIAO: meridian distribution of property and flavor: temperature; Suffering, fiber crops; Return spleen, stomach, kidney channel.Function cures mainly: warming spleen and stomach for dispelling cold, removing damp and stopping pain, parasite killing detoxifcation, the antipruritic raw meat of separating.
Herba Lycopodii: meridian distribution of property and flavor: temperature; Little hardship, suffering; Return the liver,spleen,kidney warp.Function cures mainly: expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Be used for joint aches, joint stuffiness.
Rhizoma Et Radix Notopterygii: meridian distribution of property and flavor: temperature; Hot, bitter; Return bladder, kidney channel.Function cures mainly: cold expelling, dispel the wind dehumidifying, pain relieving.Be used for the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
Radix Angelicae Pubescentis: function cures mainly: expelling wind and removing dampness, numbness relieving and pain relieving.Be used for anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache.
Ramulus Cinnamomi: meridian distribution of property and flavor: temperature; Hot, sweet; GUIXIN, lung, urinary bladder channel.Function cures mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI.Be used for anemofrigid cold, wrist abdomen cold type of pain, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Paeoniae: meridian distribution of property and flavor: be slightly cold; Bitter, acid, sweet; Return liver, spleen channel.Function cures mainly: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.It is dizzy to be used to have a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Cortex Cinnamomi: meridian distribution of property and flavor: big heat; Hot, sweet; Return spleen, kidney, the heart, Liver Channel.Function cures mainly: it is supporing yang to mend fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.Be used for sexual impotence, cold womb, chills and pain of the waist and kness is suffered from a deficiency of the kidney and is done to breathe heavily, dizziness due to yang deficiency, the conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Radix Glycyrrhizae Preparata: meridian distribution of property and flavor: flat; Sweet; GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Flos Sophorae Mel: meridian distribution of property and flavor: gas perfume (or spice), it is extremely sweet to distinguish the flavor of.Function cures mainly: tonification spleen invigorating, nourishing the lung to arrest cough, laxation relieving constipation, slow middle pain relieving, wind-damp dispelling, detoxifcation.
Good effect of the present invention is: we be the treatment gout effective prescription, when the cold-evil invades human body, or injury of meridian is obstructed for a long time, the endogenous cold external beam is not hot and suffocatingly declared, and a hair key closes, meridians block, pathogen can not outwards be distributed, and corrodes muscles and bones in the course of time, destroys the defence of human body and drainage system and the gout symptom occurs.Can warming the meridian for promoting the flow of YANG QI by taking medicine of the present invention, the diaphoresis expelling pathogenic factors from muscles, table gas and, warm extremity induce sweat with the exogenous cold of loosing, and remove limb aching pain, can relieve the pain again to take into account and get through passages through which vital energy circulates, disintegrate inner cold-evil, the YIN pathogen of dispelling, metancenter will, making the adverse-rising QI downwards, make healthy energy playback, the bad odor sedimentation, dissolve, dislike thing and just discharge from perspiration or two.Make the vital organs of the human body in order, can fundamentally treat gout, and treatment cycle is short, cost is low, and toxic and side effects is little, the therapeutic effect ideal.
Obtained tangible clinical effectiveness through clinical practice, cure rate reaches 91.5%, and total effective rate reaches 97.9%, no obvious toxic-side effects.
The specific embodiment
Further specify the present invention below in conjunction with instantiation.
Prescription example one:
Get 10 parts of Radix Aconiti Preparatas, 10 parts of Radix Aconiti Kusnezoffii Preparatas, 10 parts on Flos Carthami, 10 parts of Rhizoma Acori Graminei, 10 parts of Semen sojae atricolor, 10 parts of river MAJIAO, 10 parts of Herba Lycopodiis, 8 parts of Rhizoma Et Radix Notopterygiis, 8 parts of Radix Angelicae Pubescentiss, 8 parts of Ramulus Cinnamomi, 8 parts of the Radix Paeoniae Albas, 8 parts of Cortex Cinnamomis, 8 parts of mixed powders of Radix Glycyrrhizae Preparata are broken into 100 order granules, and baking is a ball with the Flos Sophorae Mel, and every ball weighs 8 grams.Instructions about how to take medicine and usage: every clothes one ball, every day 2 times, diaphoresis.
Prescription example two:
Get 15 parts of Radix Aconiti Preparatas, 15 parts of Radix Aconiti Kusnezoffii Preparatas, 15 parts on Flos Carthami, 15 parts of Rhizoma Acori Graminei, 15 parts of Semen sojae atricolor, 15 parts of river MAJIAO, 15 parts of Herba Lycopodiis, 10 parts of Rhizoma Et Radix Notopterygiis, Radix Angelicae Pubescentis 10,10 parts of Ramulus Cinnamomi, 10 parts of the Radix Paeoniae Albas, 10 parts of Cortex Cinnamomis, 10 parts of Radix Glycyrrhizae Preparata.Method for making and instructions about how to take medicine are with embodiment one.
Prescription example three:
Get 20 parts of Radix Aconiti Preparatas, 20 parts of Radix Aconiti Kusnezoffii Preparatas, 20 parts on Flos Carthami, 20 parts of Rhizoma Acori Graminei, 20 parts of Semen sojae atricolor, 20 parts of river MAJIAO, 20 parts of Herba Lycopodiis, 12 parts of Rhizoma Et Radix Notopterygiis, Radix Angelicae Pubescentis 12,12 parts of Ramulus Cinnamomi, 12 parts of the Radix Paeoniae Albas, 12 parts of Cortex Cinnamomis, 12 parts of Radix Glycyrrhizae Preparata, method for making and instructions about how to take medicine are with embodiment one.
It below is clinical report
From year January in January, 2008 to 2011, the inventor uses the present invention's example two treatment patient with gout 75 examples of writing out a prescription in Yantai Fushan District the People's Hospital, and treat 30 examples and carry out controlled observation with using oral colchicine and oral allopurinol the same period, receive better effects, now be reported as follows.
1, clinical data
1.1 case is selected to formulate with reference to the diagnostic criteria of gouty arthritis in " gout ": 1. joint fluid has special urate crystal; 2. confirm to have the tophus of urate crystal with chemical method or polarizing microscope; 3. have following clinical, laboratory and X line and take the photograph 6 persons in 12 of the sheet signs etc.: once above acute arthritis outbreak; Inflammation shows in 1 day and reaches the peak; Monarthritis; The joint is rubescent; Swollen or the pain of the 1st metatarsophalangeal joints; Involve the one-sided outbreak of the 1st metatarsophalangeal joints; One-sided midtarsal joints is got involved; Suspicious tophus; Hyperuricemia; The X line is taken the photograph the swelling of sheet intraarticular unsymmetry; The X line is taken the photograph sheet and is shown that the bone erosion is not accompanied in the capsule change under the cortical bone; Arthritis stage of attack joint fluid microorganism culturing feminine gender.Exclusion standard: the age is at under-18s or over-65s, to drug allergy person; Merge gouty nephropathy, renal insufficiency person; Merge serious primary disease such as the heart, liver, kidney, brain and hemopoietic system and insane; Late period arthritis severe deformity, disability person; Not medication in accordance with regulations can't be judged curative effect or data not congruent affect the treatment evaluation or safety judgement person.
1.2 physical data is observed case totally 105 examples, is divided into 2 groups at random.75 examples are organized in treatment, male 60 examples, women 15 examples; Year at age (39.5 ± 15.27); The course of disease (4.6 ± 1.1) year; Matched group 30 examples, male 20 examples, women 10 examples; Year at age (40.2 ± 14.8); The course of disease (4.5 ± 0.9) year.2 groups of physical data are learned processing by statistics, and there are no significant that meaning (P＞0.05) has comparability for difference.
2, Therapeutic Method
2.1 matched group adopts western medicine.Oral colchicine (0.5mg/ sheet) is taken 2 first, and every then 2h takes 1, when gastrointestinal symptom such as nausea,vomiting,diarrhea or remission occurring, promptly stops using.Be generally 4-8mg, change 1 of every day after the remission into, took for 1 week altogether.Oral allopurinol, each 0.1g, every day 3 times.4 weeks of the course of treatment.
2.2 the treatment group adopts 2 of oral medicine gout pill of the present invention every days, divides early, late decoction being taken warmly.4 weeks of the course of treatment.
2.3 observation item is clinical efficacy 1.; 2. blood uric acid and erythrocyte sedimentation rate change before and after the treatment.
2.4 statistical method adopts the SPSS statistical software to analyze.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, lab testing improve or are normal.Invalid: clinical symptoms does not have being clearly better or increases the weight of.
3.2 therapeutic outcome
3.212 the group clinical efficacy relatively sees Table 1.Total effective rate treatment group is that 87.9% matched group is 76.6%, 2 group of comparison, and difference has significance meaning (P＜0.05).
Table 1 clinical efficacy relatively
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| The treatment group | 75 | 13(17.3％) | 53(70.7％) | 9(12.0％) | 88.0 |
| Matched group | 30 | 2(6.6％) | 21(70％) | 7(23.3％) | 76.6 |
Compare ※ P＜0.05 with matched group
3.2.22 blood uric acid and erythrocyte sedimentation rate variation relatively see Table 2 before and after the group treatment.
Treatment group treatment back blood uric acid, erythrocyte sedimentation rate all have obvious decline, relatively preceding with treatment, difference has highly significant diversity meaning (P＜0.01) matched group, and only blood uric acid is relatively preceding with treatment, difference compares after significance meaning (P＜0.01) treatment group blood uric acid, erythrocyte sedimentation rate and treatment of control group are arranged, and difference has significance meaning (P＜0.01).
Blood uric acids and erythrocyte sedimentation rate variation comparison before and after 2 groups of treatments of table 2 (X ± S)
With preceding relatively ※ P＜0.01 of treatment; With comparison after the treatment of control group, △ P＜0.01
This shows that medicine of the present invention is better than other medicines for treatment gout effect, cures the effective percentage height.
Claims (2)
1. a Chinese medicine for the treatment of gout is characterized in that its prescription is: Radix Aconiti Preparata 10-20 part, Radix Aconiti Kusnezoffii Preparata 10-20 part, Flos Carthami 10-20 part, Rhizoma Acori Graminei 10-20 part, Semen sojae atricolor 10-20 part, river MAJIAO 10-20 part, Herba Lycopodii 10-20 part, Rhizoma Et Radix Notopterygii 8-12 part, Radix Angelicae Pubescentis 8-12, Ramulus Cinnamomi 8-12 part, Radix Paeoniae Alba 8-12 part, Cortex Cinnamomi 8-12 part, Radix Glycyrrhizae Preparata 8-12 part; Described part all refers to weight portion.
2. the Chinese medicine of treatment gout as claimed in claim 1 is characterized in that its prescription is: 20 parts of Radix Aconiti Preparatas, 20 parts of Radix Aconiti Kusnezoffii Preparatas, 20 parts on Flos Carthami, 20 parts of Rhizoma Acori Graminei, 20 parts of Semen sojae atricolor, 20 parts of river MAJIAO, 20 parts of Herba Lycopodiis, 12 parts of Rhizoma Et Radix Notopterygiis, Radix Angelicae Pubescentis 12,12 parts of Ramulus Cinnamomi, 12 parts of the Radix Paeoniae Albas, 12 parts of Cortex Cinnamomis, 12 parts of Radix Glycyrrhizae Preparata.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977207A (en) * | 2014-05-04 | 2014-08-13 | 周景龙 | Medicinal liquor for treating gout |
| CN104491039A (en) * | 2014-12-09 | 2015-04-08 | 黎颖 | Pharmaceutical composition for treating acute gout as well as preparation method and application of pharmaceutical composition |
| CN105456844A (en) * | 2015-12-31 | 2016-04-06 | 刘宝龙 | Pharmaceutical composition for preventing and treating gout |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101057915A (en) * | 2007-04-29 | 2007-10-24 | 丁延全 | Capsule for nourishing kidney and treating rheumatalgia |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101057915A (en) * | 2007-04-29 | 2007-10-24 | 丁延全 | Capsule for nourishing kidney and treating rheumatalgia |
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| Title |
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| 《中国中医急症》 20071130 呼永河 急性痛风性关节炎中医治法研究近况 1399－1402 1－2 第16卷, 第11期 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103977207A (en) * | 2014-05-04 | 2014-08-13 | 周景龙 | Medicinal liquor for treating gout |
| CN104491039A (en) * | 2014-12-09 | 2015-04-08 | 黎颖 | Pharmaceutical composition for treating acute gout as well as preparation method and application of pharmaceutical composition |
| CN105456844A (en) * | 2015-12-31 | 2016-04-06 | 刘宝龙 | Pharmaceutical composition for preventing and treating gout |
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