CN103251888A - Chinese medicine composition for treating depression - Google Patents
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Abstract
The invention provides a Chinese medicine composition for treating depression. The Chinese medicine composition is prepared from scorpion, tuber fleeceflower stem, hyperforin perforatum, fiveleaf akebia fruit, rhizoma acori graminei, polygala tenuifolia, rhizoma anemarrhenae, radix curcumae, periostracum cicada, jujube and liquorice. The composition can be used for treating depression in clinic.
Description
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of depression.
Background technology
Depression belongs to the melancholia category in motherland's medical science, and the traditional Chinese medical science thinks that melancholia is because feelings will is not relaxed the caused class disease of depression and stagnation of QI.Mainly show as and feel depressed, irritable emotion, distending pain over the hypochondrium or irritability are kind cries, and blocks various complicated symptoms such as insomnia if any foreign body in the pharynx.Depressed is because feelings will is hindered, and depression of liver-QI causes due to the five internal organs mechanism of qi discord gradually.But mainly being that liver, spleen, the heart three are dirty gets involved and disorder of QI and blood forms.The traditional Chinese medical science is thought the generation of melancholia, because of disgruntled, ponder over, institute grieved, worried seven emotions hinders, and causes the liver failing to maintain the normal flow of QI, spleen mistake fortuneization, the mind is not normal, the internal organs yin and yang qi and blood disorder forms.The just cause of disease stagnation of QI and hold damp-phlegm, food stagnation, heat stagnation person under the arm, then how true card; Prolonged illness is by gas and blood, and Sthenia is transforming into asthenia, overtaxes one's nerves as for a long time strongly fragrant, and heart spleen all loses, and hyperactivity of fire caused by deficiency of YIN etc. all belong to deficiency syndrome.At present can adopt medicines such as resist melancholy agent, tranquilizer, sleeping pill, psychosis for the treatment of depression, but toxic and side effects is big, therapeutic effect is not good enough.
Summary of the invention
The Chinese medicine composition of the treatment depression that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts Scorpio, Caulis Polygoni Multiflori, Herba Hyperici perforati, Fructus Akebiae, Rhizoma Acori Graminei, Radix Polygalae, the Rhizoma Anemarrhenae, Radix Curcumae, Periostracum Cicadae, Fructus Jujubae, Radix Glycyrrhizae is according to certain compatibility requirement, through being processed into.
Preparing Chinese medicine composition of the present invention is made by following raw material medicaments: Scorpio 40-60 part, Caulis Polygoni Multiflori 30-50 part, Herba Hyperici perforati 20-40 part, Fructus Akebiae 20-40 part, Rhizoma Acori Graminei 20-40 part, Radix Polygalae 10-20 part, Rhizoma Anemarrhenae 10-20 part, Radix Curcumae 10-20 part, Periostracum Cicadae 10-20 part, Fructus Jujubae 10-20 part, Radix Glycyrrhizae 10-20 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 50 parts of Scorpios, 40 parts of Caulis Polygoni Multiflori, 30 parts of Herba Hyperici perforatis, 30 parts of Fructus Akebiaes, 30 parts of Rhizoma Acori Graminei, 15 parts of Radix Polygalaes, 15 parts of the Rhizoma Anemarrhenaes, 15 parts of Radix Curcumaes, 15 parts of Periostracum Cicadaes, 15 parts in Fructus Jujubae, 15 parts in Radix Glycyrrhizae.
The pharmacological action of Chinese medicine of the present invention is as follows:
Scorpio: salty, hot, flat, poisonous, return Liver Channel.Relieving spasm by subduing liver-wind, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.Be used for infantile convulsion and twitch epilepsy, apoplexy and hemiplegia, rheumatoid arthritis stubborn.
Caulis Polygoni Multiflori: sweet, little hardship, flat.GUIXIN, Liver Channel.Tranquilizing by nourishing the heart dispels the wind, collateral dredging.Be used for insomnia, dreaminess, blood deficiency, numbness of the skin, rheumatic arthralgia, diseases such as rubella pruritus.
Herba Hyperici perforati: bitter, puckery, flat.Return Liver Channel.Astringing to arrest bleeding, regulating menstruation lactogenesis, heat-clearing and toxic substances removing, dampness removing.Be used for spitting of blood, spit blood, discharging fresh blood stool, metrorrhagia, traumatic hemorrhage, newborn woman's agalactia, jaundice is had sore throat, conjunctival congestion and swelling pain, urinary tract infection, mouth and nose are given birth to skin ulcer, diseases such as carbuncle furuncle and phyma poison.
Fructus Akebiae: little hardship, property are put down.Return liver, stomach, urinary bladder channel.Dispersing the stagnated liver-QI for regulating the stomach, promoting blood circulation and stopping pain, hard masses softening and resolving, diuresis.Be used for stagnation of liver-QI and stomach-QI, gastral cavity abdomen, the side of body help distending pain, and diet does not disappear, and dysentery is just let out, hernia pain, lumbago, amenorrhea dysmenorrhea, goiter scrofula, malignant tumor etc.
Rhizoma Acori Graminei: hot, bitter, tepor, GUIXIN, liver, spleen channel.Eliminate phlegm for resuscitation removing dampness to restore normal function of the stomach, mind calming Fructus Alpiniae Oxyphyllae.Be used for the calentura coma, forgetful, insomnia, tinnitus.
Radix Polygalae: bitter, hot, tepor, GUIXIN, kidney, lung meridian.Mind tranquilizing and the heart calming eliminates the phlegm and has one's ideas straightened out, the dissipation carbuncle.Be used for palpitation with fear, insomnia forgetfulness, phlegmatic mental confusion, epilepsy is gone mad.
The Rhizoma Anemarrhenae: sweet, bitter, cold, return lung, stomach, kidney channel.Clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.Be used for calentura excessive thirst, cough due to lung-heat.
Radix Curcumae: bitter, hot, cold, return liver, gallbladder, heart channel.The blood-activating and qi-promoting pain relieving, resolving depression clears away heart-fire, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood.The card that is used for calentura coma, epilepsy unconsciousness due to blockage of phlegm.
Periostracum Cicadae: sweet, cold, return lung, Liver Channel.Dispelling wind and heat pathogens, rash is antipruritic, relieving convulsion.Be used for conjunctival congestion cataracta, infantile convulsion night cry.
Fructus Jujubae: sweet, warm.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind relaxes the property of medicine.Be used for insufficiency of the spleen anorexia and loose stool, fatigue and weakness, blood deficiency and yellow complexion and women's internal organs, mind uneasiness, protection healthy energy etc.
Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.The QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.The severe palpitation, the irregularly intermittent and regularly intermittent pulse that are used for deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.
Scorpio has relieving spasm by subduing liver-wind among the present invention, removing obstruction in the collateral to relieve pain, the effect of dispersing pathogen accumulation, find that through clinical practice depression is had unique curative effect, be monarch drug, with Caulis Polygoni Multiflori, Herba Hyperici perforati, Fructus Akebiae, Rhizoma Acori Graminei, Radix Polygalae, the Rhizoma Anemarrhenae, Radix Curcumae, Periostracum Cicadae, Fructus Jujubae, the Radix Glycyrrhizae compatibility uses, and reaches the purpose for the treatment of depression.
Chinese medicine composition of the present invention was in 2009 to 2012 clinical observation depression 50 routine patients, and clinical report is as follows:
1, physical data
Among the 50 routine patients, women's 28 examples, male's 22 examples, at minimum 18 years old of age, maximum 67 years old, the course of disease was many at 3 months to 10 years, 48.3 years old mean age.
2, diagnostic criteria
" Chinese mental disorder classification and diagnostic criteria the 3rd edition " (CCMD-3) diagnostic criteria of depression, preceding 17 〉=18 minutes of Hamilton depressive scale (HAMD), do not have other neuropsychiatric diseases, alcohol-free and drug dependence and similar drug allergy history are got rid of diseases such as the heart, liver, kidney.
3, Therapeutic Method
3.1 prescription: Scorpio 50g, Caulis Polygoni Multiflori 40g, Herba Hyperici perforati 30g, Fructus Akebiae 30g, Rhizoma Acori Graminei 30g, Radix Polygalae 15g, Rhizoma Anemarrhenae 15g, Radix Curcumae 15g, Periostracum Cicadae 15g, Fructus Jujubae 15g, Radix Glycyrrhizae 15g.
3.2 preparation method: said medicine technology is routinely made decoction.
3.3 instructions of taking: each 1 dose, every day 2 times, 4 weeks were 1 course for the treatment of.
4, therapeutic outcome:
4.1 treatment evaluation criteria: adopt HAMD evaluation clinical efficacy, subtract the evaluation of branch rate with HAMD, adopt recovery from illness, effective, invalid 3 grades of standards of grading, subtract branch rate 〉=75% and be recovery from illness, 25～75% is that effectively＜25% is invalid.Total effective rate (%)=[(recovery from illness+effectively)/total routine number] * 100%.
4.2 result: among the 50 routine patients, 33 examples of fully recovering (66%), effective 15 examples (30%), invalid 2 examples (4%), total effective rate is 96%.
5, model case
5.1 Lee, the man 45 years old, has suffered from depression and has examined, the frequent heart of readme occurs gloomy, lonely, dreary, grieved, forfeiture and kith and kin, the extraneous interest that exchanges dealing, sigh frequently, dejected, sobbing in August, 2009.Once used many medicines all not prove effective.Taken the Chinese medicine that the present invention treats depression, after three courses for the treatment of, disease obtains recovery from illness.
5.2 fourth, the woman, 29 years old, not smooth because of work, susceptible to lose temper due to restlessness appears, and depressed, the recent months sx is often flown into a rage, and is emotional, two side of body and distending pain of the breast, inappetence, insomnia and dreamful sleep, red tongue with yellow fur, stringy pulse.Taken the Chinese medicine that the present invention treats depression, after three courses for the treatment of, disease obtains recovery from illness.
5.3 Huang, the woman, 65 years old, to have a sleepless night for many years, appearance in nearly several months is depressed, and insomnia increases the weight of, and lies awake all night the stabbing hypochondrium pain that often shows effect, dysmenorrhea, dark tongue quality, stringy and hesitant pulse sometimes.Taken the Chinese medicine composition that the present invention treats depression, after three courses for the treatment of, disease obtains recovery from illness.
The specific embodiment
The present invention is further illustrated below in conjunction with embodiment, and following this embodiment only for explanation the present invention to the present invention without limits.
Embodiment 1, a kind of Chinese medicine composition for the treatment of depression, and it is to be made by following raw material medicaments: Scorpio 40g, Caulis Polygoni Multiflori 30g, Herba Hyperici perforati 20g, Fructus Akebiae 20g, Rhizoma Acori Graminei 20g, Radix Polygalae 10g, Rhizoma Anemarrhenae 10g, Radix Curcumae 10g, Periostracum Cicadae 10g, Fructus Jujubae 10g, Radix Glycyrrhizae 10g.
Embodiment 2, a kind of Chinese medicine composition for the treatment of depression, and it is to be made by following raw material medicaments: Scorpio 50g, Caulis Polygoni Multiflori 40g, Herba Hyperici perforati 30g, Fructus Akebiae 30g, Rhizoma Acori Graminei 30g, Radix Polygalae 15g, Rhizoma Anemarrhenae 15g, Radix Curcumae 15g, Periostracum Cicadae 15g, Fructus Jujubae 15g, Radix Glycyrrhizae 15g.
Embodiment 3, a kind of Chinese medicine composition for the treatment of depression, and it is to be made by following raw material medicaments: Scorpio 60g, Caulis Polygoni Multiflori 50g, Herba Hyperici perforati 40g, Fructus Akebiae 40g, Rhizoma Acori Graminei 40g, Radix Polygalae 20g, Rhizoma Anemarrhenae 20g, Radix Curcumae 20g, Periostracum Cicadae 20g, Fructus Jujubae 20g, Radix Glycyrrhizae 20g.
Claims (2)
1. treat depressed Chinese medicine composition for one kind, it is characterized in that it is to be made by following raw material medicaments:
Scorpio 40-60 part, Caulis Polygoni Multiflori 30-50 part, Herba Hyperici perforati 20-40 part, Fructus Akebiae 20-40 part, Rhizoma Acori Graminei 20-40 part, Radix Polygalae 10-20 part, Rhizoma Anemarrhenae 10-20 part, Radix Curcumae 10-20 part, Periostracum Cicadae 10-20 part, Fructus Jujubae 10-20 part, Radix Glycyrrhizae 10-20 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments:
50 parts of Scorpios, 40 parts of Caulis Polygoni Multiflori, 30 parts of Herba Hyperici perforatis, 30 parts of Fructus Akebiaes, 30 parts of Rhizoma Acori Graminei, 15 parts of Radix Polygalaes, 15 parts of the Rhizoma Anemarrhenaes, 15 parts of Radix Curcumaes, 15 parts of Periostracum Cicadaes, 15 parts in Fructus Jujubae, 15 parts in Radix Glycyrrhizae.
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| CN 201310189004 CN103251888A (en) | 2013-05-10 | 2013-05-10 | Chinese medicine composition for treating depression |
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| CN 201310189004 CN103251888A (en) | 2013-05-10 | 2013-05-10 | Chinese medicine composition for treating depression |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173933A (en) * | 2014-08-25 | 2014-12-03 | 王浩 | Traditional Chinese medicine composition for treating depressive disorder |
| CN104491760A (en) * | 2015-01-15 | 2015-04-08 | 柏跃龙 | Traditional Chinese medicine composition for treating depression |
| CN104606636A (en) * | 2015-01-29 | 2015-05-13 | 北京中医药大学东方医院 | Traditional Chinese medicine composition for treating depression and preparation method thereof |
| CN105582480A (en) * | 2016-03-03 | 2016-05-18 | 林炜 | Traditional Chinese medicine composition for treating depression |
-
2013
- 2013-05-10 CN CN 201310189004 patent/CN103251888A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104173933A (en) * | 2014-08-25 | 2014-12-03 | 王浩 | Traditional Chinese medicine composition for treating depressive disorder |
| CN104491760A (en) * | 2015-01-15 | 2015-04-08 | 柏跃龙 | Traditional Chinese medicine composition for treating depression |
| CN104606636A (en) * | 2015-01-29 | 2015-05-13 | 北京中医药大学东方医院 | Traditional Chinese medicine composition for treating depression and preparation method thereof |
| CN104606636B (en) * | 2015-01-29 | 2018-03-06 | 北京中医药大学东方医院 | A kind of Chinese medicine composition for treating depression and preparation method thereof |
| CN105582480A (en) * | 2016-03-03 | 2016-05-18 | 林炜 | Traditional Chinese medicine composition for treating depression |
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Application publication date: 20130821 |