CN103784804A - Pharmaceutical composition for treating benign prostatic hyperplasia - Google Patents

Pharmaceutical composition for treating benign prostatic hyperplasia Download PDF

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Publication number
CN103784804A
CN103784804A CN201410078228.2A CN201410078228A CN103784804A CN 103784804 A CN103784804 A CN 103784804A CN 201410078228 A CN201410078228 A CN 201410078228A CN 103784804 A CN103784804 A CN 103784804A
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parts
herba
prostatic hyperplasia
radix
rhizoma
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CN201410078228.2A
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陈磊
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Abstract

The invention relates to a pharmaceutical composition for treating benign prostatic hyperplasia. The pharmaceutical composition comprises, by weight, 13-17 parts of radix astragali, 13-17 parts of Chinese yam, 13-17 parts of pangolin, 11-13 parts of polygonum aviculare, 11-13 parts of salvia miltiorrhiza, 11-13 parts of talc, 11-13 parts of achyranthes bidentata, 11-13 parts of prepared rehmannia roots, 11-13 parts of dianthus superbus, 11-13 parts of dandelion, 6-8 artemisia anomata, 6-8 parts of algae, 6-8 parts of fructus forsythiae, 6-8 parts of semen plantaginis, 6-8 parts of pericarpium citri reticulatae viride, 6-8 parts of radix angelicae tuhuo, 6-8 parts of lalang grass rhizome, 6-8 parts of golden cypress, 6-8 parts of polygonum cuspidatum, 2-4 parts of the seeds of cowherb, 2-4 parts of cinnamon, 2-4 parts of gizzard pepsin, 2-4 parts of pillworm, and 2-4 parts of amber. The pharmaceutical composition has the advantages of being definite in curative effect, and little in toxic and side effect.

Description

A kind of Chinese medicine composition for the treatment of prostatic hyperplasia
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine composition for the treatment of prostatic hyperplasia.
Background technology
Prostatic hyperplasia is one of male senile patient common disease, cumulative many with population in the world senescence onset of illness.Prostatic hyperplasia clinical symptoms main manifestations is frequent micturition, dysuria, urine retention and hematuria etc., and sickness rate increased progressively with the age, but not necessarily has clinical symptoms while having preneoplastic lesions.A lot of about the study of incident mechanism of prostatic hyperplasia, but the cause of disease still fails to illustrate so far.Current known prostatic hyperplasia must possess testis and exist and two conditions of age growth.Along with the going deep into of basic research, think that prostatic hyperplasia is the interactional result of prostate epithelial cell and Interstitial cell in recent years.
At present, the conventional medicine for the treatment of prostatic hyperplasia has 5α-reductase inhibitor, alpha-blocking agent, androgen antagonist and derivant, plant amedica etc.There is the deficiencies such as curative effect is not obvious, toxic and side effects is large in it.
Summary of the invention
The technical problem to be solved in the present invention is: for solving the deficiencies in the prior art, the invention provides a kind of Chinese medicine composition for the treatment of prostatic hyperplasia, the present invention has advantages of that determined curative effect, toxic and side effects are little.
A kind of Chinese medicine composition for the treatment of prostatic hyperplasia, crude drug by following weight portion is made: Radix Astragali 13-17 part, Rhizoma Dioscoreae 13-17 part, Squama Manis 13-17 part, Herba Polygoni Avicularis 11-13 part, Radix Salviae Miltiorrhizae 11-13 part, Talcum 11-13 part, Radix Achyranthis Bidentatae 11-13 part, Radix Rehmanniae Preparata 11-13 part, Herba Dianthi 11-13 part, Herba Taraxaci 11-13 part, Herba Artemisiae Anomalae 6-8 part, Sargassum 6-8 part, Fructus Forsythiae 6-8 part, Semen Plantaginis 6-8 part, Pericarpium Citri Reticulatae Viride 6-8 part, Radix Angelicae Pubescentis 6-8 part, Rhizoma Imperatae 6-8 part, Cortex Phellodendri 6-8 part, Rhizoma Polygoni Cuspidati 6-8 part, Semen Vaccariae 2-4 part, Cortex Cinnamomi 2-4 part, Endothelium Corneum Gigeriae Galli 2-4 part, Armadillidium 2-4 part, succinum 2-4 part.
The Chinese medicine composition of described treatment prostatic hyperplasia, its preferably: the crude drug by following weight portion is made: 15 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, Squama Manis 15 12 parts of Fen, Herba Polygoni Avicularis, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts, Talcum, 12 parts of Radix Achyranthis Bidentataes, 12 parts of Radix Rehmanniae Preparata, 12 parts of Herba Dianthis, 12 parts of Herba Taraxacis, 7 parts of Herba Artemisiae Anomalaes, 7 parts of Sargassums, 7 parts of Fructus Forsythiaes, 7 parts of Semen Plantaginiss, 7 parts, Pericarpium Citri Reticulatae Viride, 7 parts of Radix Angelicae Pubescentiss, 7 parts of Rhizoma Imperataes, 7 parts of Cortex Phellodendris, 7 parts of Rhizoma Polygoni Cuspidati, 3 parts of Semen Vaccariae, 3 parts of Cortex Cinnamomis, 3 parts of Endothelium Corneum Gigeriae Galli, 3 parts of Armadillidiums, 3 parts of succinums.
The preparation method of the Chinese medicine composition of described treatment prostatic hyperplasia, is characterized in that: Chinese medicinal preparation method is routinely made and is suitable for medicinal oral drugs.
The Chinese medicine composition of described treatment prostatic hyperplasia is as the application of preparation treatment prostatic hyperplasia medicine.
The pharmaceutical characteristic of each crude drug of the present invention is as follows:
The Radix Astragali: sweet, tepor, returns lung, spleen, liver, kidney channel; Effect: polishing consolidating superficial resistance, holder skin ulcer granulation promoting.
Rhizoma Dioscoreae: sweet, flat, return lung, spleen, kidney channel; Effect: spleen invigorating, tonifying the lung, reinforces the kidney, benefit essence.
Squama Manis: salty, be slightly cold.Return liver, stomach warp.Effect: the stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.
Herba Polygoni Avicularis: hardship, is slightly cold.Return urinary bladder channel.Effect: inducing diuresis for treating stranguria syndrome, parasite killing, antipruritic.
Radix Salviae Miltiorrhizae: bitter, be slightly cold, GUIXIN, Liver Channel; Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind.
Talcum: sweet, light, cold.Return bladder, lung, stomach warp.Effect: inducing diuresis for treating stranguria syndrome, clearing away summer-heat, damp eliminating sore.
Radix Achyranthis Bidentatae: bitter, sour, flat.Return liver, kidney channel.Effect: invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.
Radix Rehmanniae Preparata: sweet, tepor, returns liver, kidney channel; Effect: nourishing YIN and supplementing blood, beneficial essence is filled out marrow.
Herba Dianthi: hardship, cold.GUIXIN, small intestine meridian.Effect: inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow.
Herba Taraxaci: bitter, sweet, cold liver, the stomach warp of returning; Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.
Herba Artemisiae Anomalae: hardship, temperature.Enter the heart, spleen channel.Effect: removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling.
Sargassum: cold; Salty; Return liver, kidney channel.Effect: hard masses softening and resolving, expectorant, diuretic.
Fructus Forsythiae: hardship, be slightly cold, return lung, the heart, small intestine meridian; Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Herba Plantaginis: sweet, cold, return liver, kidney, lung, small intestine meridian; Effect: clearing away heat and promoting diuresis, eliminate the phlegm, removing heat from blood, removing toxic substances.
Pericarpium Citri Reticulatae Viride: toil, tepor; Enter liver, gallbladder meridian; Effect: soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant.
Radix Angelicae Pubescentis: pungent, bitter, tepor.Return kidney, urinary bladder channel.Effect: expelling wind and removing dampness, numbness relieving and pain relieving.
Rhizoma Imperatae: sweet, cold.Return lung, stomach, urinary bladder channel.Effect: cooling blood for hemostasis, clearing away heat and promoting diuresis.
Cortex Phellodendri: hardship, cold; Return kidney, urinary bladder channel; Effect: heat clearing and damp drying, pathogenic fire purging is except steaming, detoxification sore treatment.
Rhizoma Polygoni Cuspidati: micro-hardship, be slightly cold, return liver, gallbladder, lung meridian; Effect: expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.
Semen Vaccariae: hardship, flat; Enter liver, stomach warp; Effect: promoting the circulation of blood is stimulated the menstrual flow, expedites the emergence of stimulating milk secretion, detumescence sore.
Cortex Cinnamomi: pungent, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel; Effect: mend supporing yang, the let the fire back to its origin of fire, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.
Endothelium Corneum Gigeriae Galli: sweet in the mouth, property is flat, returns spleen, stomach, kidney, urinary bladder channel.Effect: strengthening the spleen to promote digestion, arresting seminal emission, eliminating mass fossil.
Armadillidium: sour in the mouth, salty, cool in nature, return liver, kidney channel.Effect: removing blood stasis with potent drugs eliminating mass, stimulate the menstrual flow, diuretic, removing toxic substances, pain relieving.
Succinum: sweet, flat.Enter the heart, liver, small intestine meridian.Effect: tranquillizing the mind by relieving convulsion, dissipating blood stasis hemostasis, relieving stranguria by diuresis.
The beneficial effect that the present invention compared with prior art had is: the present invention is under Traditional Chinese medical theory and clinical experience guidance, choose each crude drug and proportioning thereof, there is clearing away heat-damp and promoting diuresis, inrigorating qi and promoting blood circulation, function that detumescence is treating stranguria, reach the object for the treatment of prostatic hyperplasia.
Below in conjunction with clinical experiment, beneficial effect of the present invention is described:
(1) clinical data: the present invention treats Patients with Prostatic Hyperplasia 45 examples altogether, the age is 55-72 year.
(2) Therapeutic Method: the oral drugs that Chinese medicine composition of the present invention is made can be decoction, tablet, pill and capsule etc.Take decoction as example, 1 pair of every day, point take for 2 times, early, respectively take 1 evening, within 20 days, is 1 course for the treatment of.
(3) the standard of curative effect evaluation:
Cure: unobstructed micturition, prostatic examination is obviously dwindled, without residual urine;
Take a turn for the better: the symptom of urinating takes a turn for the better, residual urine reduces;
Do not heal: symptom and every inspection are all without improving.
(4) therapeutic outcome: the present invention treats Patients with Prostatic Hyperplasia 45 examples altogether, through 1-3 course of therapy, cures 39 examples, accounts for 87%, and 6 examples that take a turn for the better, account for 13%, and effective percentage is 100%, has no any side effect.Cure in 39 examples, cure 10 examples 1 course for the treatment of, cure 22 examples 2 courses for the treatment of, cure 7 examples 3 courses for the treatment of.Result shows, the present invention has advantages of that determined curative effect, toxic and side effects are little.
(5) model case
1, Lee so-and-so, man, 58 years old, suffer from prostatic hyperplasia 2 years, Symptoms is: oliguria Huang is red, the puckery pain of frequent micturition, drop is not smooth, little distention and fullness in the abdomen, red tongue, yellow and greasy fur, rapid pulse.After using 1 course for the treatment of of Chinese medicine preparation of the present invention, fully recover, follow up a case by regular visits to not recurrence in 1 year.
2, marquis so-and-so, man, 70 years old, suffer from the prostatic hyperplasia several years, Symptoms is: perineum, lower abdominal distention pain, dysuria, hematuria, purplish tongue or have ecchymosis, tongue is white, deep and stringy pulse.After using 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom is obviously improved, and not recurrence in 1 year is followed up a case by regular visits in 3 recoveries from illness courses for the treatment of.
3, the Qin so-and-so, man, 60 years old, be diagnosed as on inspection prostatic hyperplasia, Symptoms is: sagging distention in the smaller abdomen, urine wish solution is not well, enuresis nocturna, pale tongue, white and thin fur, soft and thready pulse.After 1 course for the treatment of of Chinese medicine preparation of invention, symptom is obviously improved, and not recurrence in 2 years is followed up a case by regular visits in 2 recoveries from illness courses for the treatment of.
The specific embodiment
Embodiment 1:
Treat a Chinese medicine composition for prostatic hyperplasia, made by the crude drug of following weight portion: 15 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, Squama Manis 15 12 parts of Fen, Herba Polygoni Avicularis, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts, Talcum, 12 parts of Radix Achyranthis Bidentataes, 12 parts of Radix Rehmanniae Preparata, 12 parts of Herba Dianthis, 12 parts of Herba Taraxacis, 7 parts of Herba Artemisiae Anomalaes, 7 parts of Sargassums, 7 parts of Fructus Forsythiaes, 7 parts of Semen Plantaginiss, 7 parts, Pericarpium Citri Reticulatae Viride, 7 parts of Radix Angelicae Pubescentiss, 7 parts of Rhizoma Imperataes, 7 parts of Cortex Phellodendris, 7 parts of Rhizoma Polygoni Cuspidati, 3 parts of Semen Vaccariae, 3 parts of Cortex Cinnamomis, 3 parts of Endothelium Corneum Gigeriae Galli, 3 parts of Armadillidiums, 3 parts of succinums.
Its preparation method is: Chinese medicinal preparation method is routinely made and is suitable for medicinal oral drugs.
Embodiment 2:
Treat a Chinese medicine composition for prostatic hyperplasia, made by the crude drug of following weight portion: 13 parts of the Radixs Astragali, 13 parts of Rhizoma Dioscoreaes, Squama Manis 13 11 parts of Fen, Herba Polygoni Avicularis, 11 parts of Radix Salviae Miltiorrhizaes, 11 parts, Talcum, 11 parts of Radix Achyranthis Bidentataes, 11 parts of Radix Rehmanniae Preparata, 11 parts of Herba Dianthis, 11 parts of Herba Taraxacis, 6 parts of Herba Artemisiae Anomalaes, 6 parts of Sargassums, 6 parts of Fructus Forsythiaes, 6 parts of Semen Plantaginiss, 6 parts, Pericarpium Citri Reticulatae Viride, 6 parts of Radix Angelicae Pubescentiss, 6 parts of Rhizoma Imperataes, 6 parts of Cortex Phellodendris, 6 parts of Rhizoma Polygoni Cuspidati, 2 parts of Semen Vaccariae, 2 parts of Cortex Cinnamomis, 2 parts of Endothelium Corneum Gigeriae Galli, 2 parts of Armadillidiums, 2 parts of succinums.
Its preparation method is: Chinese medicinal preparation method is routinely made and is suitable for medicinal oral drugs.
Embodiment 3:
Treat a Chinese medicine composition for prostatic hyperplasia, made by the crude drug of following weight portion: 17 parts of the Radixs Astragali, 17 parts of Rhizoma Dioscoreaes, Squama Manis 17 13 parts of Fen, Herba Polygoni Avicularis, 13 parts of Radix Salviae Miltiorrhizaes, 13 parts, Talcum, 13 parts of Radix Achyranthis Bidentataes, 13 parts of Radix Rehmanniae Preparata, 13 parts of Herba Dianthis, 13 parts of Herba Taraxacis, 8 parts of Herba Artemisiae Anomalaes, 8 parts of Sargassums, 8 parts of Fructus Forsythiaes, 8 parts of Semen Plantaginiss, 8 parts, Pericarpium Citri Reticulatae Viride, 8 parts of Radix Angelicae Pubescentiss, 8 parts of Rhizoma Imperataes, 8 parts of Cortex Phellodendris, 8 parts of Rhizoma Polygoni Cuspidati, 4 parts of Semen Vaccariae, 4 parts of Cortex Cinnamomis, 4 parts of Endothelium Corneum Gigeriae Galli, 4 parts of Armadillidiums, 4 parts of succinums.
Its preparation method is: Chinese medicinal preparation method is routinely made and is suitable for medicinal oral drugs.
Embodiment 4:
Treat a Chinese medicine composition for prostatic hyperplasia, made by the crude drug of following weight portion: 15 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, Squama Manis 15 11 parts of Fen, Herba Polygoni Avicularis, 11 parts of Radix Salviae Miltiorrhizaes, 11 parts, Talcum, 11 parts of Radix Achyranthis Bidentataes, 11 parts of Radix Rehmanniae Preparata, 11 parts of Herba Dianthis, 11 parts of Herba Taraxacis, 8 parts of Herba Artemisiae Anomalaes, 8 parts of Sargassums, 8 parts of Fructus Forsythiaes, 8 parts of Semen Plantaginiss, 8 parts, Pericarpium Citri Reticulatae Viride, 8 parts of Radix Angelicae Pubescentiss, 8 parts of Rhizoma Imperataes, 8 parts of Cortex Phellodendris, 8 parts of Rhizoma Polygoni Cuspidati, 2 parts of Semen Vaccariae, 2 parts of Cortex Cinnamomis, 2 parts of Endothelium Corneum Gigeriae Galli, 2 parts of Armadillidiums, 2 parts of succinums.
Its preparation method is: Chinese medicinal preparation method is routinely made and is suitable for medicinal oral drugs.

Claims (4)

1. treat the Chinese medicine composition of prostatic hyperplasia for one kind, it is characterized in that: the crude drug by following weight portion is made: Radix Astragali 13-17 part, Rhizoma Dioscoreae 13-17 part, Squama Manis 13-17 part, Herba Polygoni Avicularis 11-13 part, Radix Salviae Miltiorrhizae 11-13 part, Talcum 11-13 part, Radix Achyranthis Bidentatae 11-13 part, Radix Rehmanniae Preparata 11-13 part, Herba Dianthi 11-13 part, Herba Taraxaci 11-13 part, Herba Artemisiae Anomalae 6-8 part, Sargassum 6-8 part, Fructus Forsythiae 6-8 part, Semen Plantaginis 6-8 part, Pericarpium Citri Reticulatae Viride 6-8 part, Radix Angelicae Pubescentis 6-8 part, Rhizoma Imperatae 6-8 part, Cortex Phellodendri 6-8 part, Rhizoma Polygoni Cuspidati 6-8 part, Semen Vaccariae 2-4 part, Cortex Cinnamomi 2-4 part, Endothelium Corneum Gigeriae Galli 2-4 part, Armadillidium 2-4 part, succinum 2-4 part.
2. the Chinese medicine composition for the treatment of prostatic hyperplasia according to claim 1, is characterized in that: the crude drug by following weight portion is made: 15 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, Squama Manis 15 12 parts of Fen, Herba Polygoni Avicularis, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts, Talcum, 12 parts of Radix Achyranthis Bidentataes, 12 parts of Radix Rehmanniae Preparata, 12 parts of Herba Dianthis, 12 parts of Herba Taraxacis, 7 parts of Herba Artemisiae Anomalaes, 7 parts of Sargassums, 7 parts of Fructus Forsythiaes, 7 parts of Semen Plantaginiss, 7 parts, Pericarpium Citri Reticulatae Viride, 7 parts of Radix Angelicae Pubescentiss, 7 parts of Rhizoma Imperataes, 7 parts of Cortex Phellodendris, 7 parts of Rhizoma Polygoni Cuspidati, 3 parts of Semen Vaccariae, 3 parts of Cortex Cinnamomis, 3 parts of Endothelium Corneum Gigeriae Galli, 3 parts of Armadillidiums, 3 parts of succinums.
3. the preparation method of the Chinese medicine composition for the treatment of prostatic hyperplasia according to claim 1 and 2, is characterized in that: Chinese medicinal preparation method is routinely made and is suitable for medicinal oral drugs.
4. the Chinese medicine composition for the treatment of prostatic hyperplasia according to claim 1 and 2 is as the application of preparation treatment prostatic hyperplasia medicine.
CN201410078228.2A 2014-03-05 2014-03-05 Pharmaceutical composition for treating benign prostatic hyperplasia Pending CN103784804A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147157A (en) * 2014-09-01 2014-11-19 上海浦东高星生物技术研究所 Chinese patent medicine for treating prostatic hyperplasia of old people
CN104367951A (en) * 2014-11-13 2015-02-25 李鸿光 Medicine for treating prostate hyperplasia
CN104435450A (en) * 2014-12-25 2015-03-25 崔合芳 Traditional Chinese medicine composition for treating qi stagnation and blood stasis type prostate hyperplasia and preparation method thereof
CN105920544A (en) * 2016-06-27 2016-09-07 许建成 Traditional Chinese medicinal preparation for treating prostate hyperplasia and preparation method thereof
CN106177281A (en) * 2016-08-18 2016-12-07 黄逢雨 A kind of Chinese medicine composition treating prostatic hyperplasia
CN104147157B (en) * 2014-09-01 2017-01-04 上海浦东高星生物技术研究所 A kind of Chinese patent medicine treating old man's prostatic hyperplasia

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Publication number Priority date Publication date Assignee Title
CN1951470A (en) * 2006-09-30 2007-04-25 刘唐保 Medicament for treating chronic prostatitis and prostatic hyperplasia
CN101732660A (en) * 2009-12-25 2010-06-16 卢速江 Chinese medicinal preparation for treating prostate disease and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1951470A (en) * 2006-09-30 2007-04-25 刘唐保 Medicament for treating chronic prostatitis and prostatic hyperplasia
CN101732660A (en) * 2009-12-25 2010-06-16 卢速江 Chinese medicinal preparation for treating prostate disease and preparation method thereof

Non-Patent Citations (1)

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詹慧春等: "中医药治疗前列腺增生症的临床研究概况", 《实用中西医结合临床》 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104147157A (en) * 2014-09-01 2014-11-19 上海浦东高星生物技术研究所 Chinese patent medicine for treating prostatic hyperplasia of old people
CN104147157B (en) * 2014-09-01 2017-01-04 上海浦东高星生物技术研究所 A kind of Chinese patent medicine treating old man's prostatic hyperplasia
CN104367951A (en) * 2014-11-13 2015-02-25 李鸿光 Medicine for treating prostate hyperplasia
CN104435450A (en) * 2014-12-25 2015-03-25 崔合芳 Traditional Chinese medicine composition for treating qi stagnation and blood stasis type prostate hyperplasia and preparation method thereof
CN105920544A (en) * 2016-06-27 2016-09-07 许建成 Traditional Chinese medicinal preparation for treating prostate hyperplasia and preparation method thereof
CN106177281A (en) * 2016-08-18 2016-12-07 黄逢雨 A kind of Chinese medicine composition treating prostatic hyperplasia

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