CN105079184A - Medicine for treating osteoporosis - Google Patents
Medicine for treating osteoporosis Download PDFInfo
- Publication number
- CN105079184A CN105079184A CN201510560675.6A CN201510560675A CN105079184A CN 105079184 A CN105079184 A CN 105079184A CN 201510560675 A CN201510560675 A CN 201510560675A CN 105079184 A CN105079184 A CN 105079184A
- Authority
- CN
- China
- Prior art keywords
- parts
- medicine
- herba
- osteoporosis
- active pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of medicine compositions, in particular to a medicine for treating osteoporosis. The medicine is characterized by being prepared from the following active pharmaceutical ingredients in parts by weight: 5-9 parts of tortoise plastron, 4-7 parts of lycopodiella inundata (L.) Holub, 4-8 parts of shorthorned epimedium herb, 4-7 parts of stem of falsenettleleaf pepper, 4-8 parts of creeping psychotria branchlet and leaf, 5-8 parts of garden balsam root, 6-9 parts of acer mono, 6-9 parts of radix morindae officinalis, 7-9 parts of sambucus thunbergiana, 6-9 parts of aralia chinensis, 2-5 parts of ardisia villosa, 6-9 parts of laciniate blumea herb, 2-5 parts of pyrola, 4-6 parts of Chinese maple root, 2-4 parts of semen astragali complanati, 4-6 parts of all-grass of arcuaate iolet, 2-4 parts of canarium pimela and 7-9 parts of meadow fescue. A preparation method of the medicine comprises the following steps: soaking the active pharmaceutical ingredients in water, boiling, and removing dregs to obtain a filtrate of the medicine. The medicine has the efficacies of nourishing liver and kidney, and strengthening muscles and bones; through scientific compatibility of the active pharmaceutical ingredients with different medicine properties, an ideal treatment effect can be achieved, the medicine can directly reach lesions, the curative time is short, and the possibility of recurrence after osteoporosis is cured is low.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically one treats osteoporotic medicine.
Background technology
As everyone knows, osteoporosis is one group of osteopathia that multiple reasons causes, and osseous tissue has normal calcification, and calcium salt and substrate are normal rates, and the metabolic osteopathy being reduced to feature with unit volume inner bone tissues amount becomes.In most osteoporosis, caused by the minimizing of osseous tissue increases mainly due to bone absorption.Fall ill how slowly indivedual very fast, with skeleton pain, be easy to fracture for feature biochemical analysis is normal.The visible cortical bone of pathological anatomy is belittled, and bone trabecula sparse atrophy osteoid layer is not thick.
At present, the whole world about has 200,000,000 people to suffer from osteoporosis, and its sickness rate has leapt to the 7th of the various commonly encountered diseases in the world.Also report is had to show the 6th that occupies common disease.Osteoporosis has been acknowledged as serious social public health problem.Western medicine: absorbing state is uncertain, affects appetite, easily repeatedly.
Summary of the invention
Object of the present invention is exactly to overcome existing technical deficiency, one is provided to treat osteoporotic medicine, there is nourishing the liver and kidney, effect of bone and muscle strengthening, adopts the Chinese crude drug of different properties, has carried out scientific compatibility, desirable therapeutic effect can be reached, the through focus of energy, healing time is short, not easily recurs after healing.
The technical scheme that the present invention solves the problems of the technologies described above employing is: one treats osteoporotic medicine, it is characterized in that being made up of the crude drug of following weight portion: Carapax et Plastrum Testudinis 5 ~ 9, little Lycopodium clavatum 4 ~ 7, Herba Epimedii 4 ~ 8, Caulis Piperis Boehmeriaefolii 4 ~ 7, Ramulus et Folium Psychotriae Serpentis 4 ~ 8, Radix Impatientis 5 ~ 8, Acer mono Maxim. 6 ~ 9, Radix Morindae Officinalis 6 ~ 9, Rhizoma seu Herba Elatostematis stewardii 7 ~ 9, Cortex araliae chinensis 6 ~ 9, snow red 2 ~ 5, the Herba Blumeae Laciniatae 6 ~ 9, Herba Pyrolae 2 ~ 5, Cortex Aceris Sinensis 4 ~ 6, Semen Astragali Complanati 2 ~ 4, thunderclap pasture and water 4 ~ 6, Fructus Canarii Pimelae 2 ~ 4, Isodon ternifolius 7 ~ 9, by medicinal for above-mentioned raw materials water soaking, to remove slag after decocting to obtain filtrate.
The invention has the beneficial effects as follows to have nourishing the liver and kidney, effect of bone and muscle strengthening, adopt the Chinese crude drug of different properties, carried out scientific compatibility, can reach desirable therapeutic effect, focus of going directly, healing time is short, not easily recurs after healing.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
Adopt Carapax et Plastrum Testudinis, little Lycopodium clavatum, Herba Epimedii, Caulis Piperis Boehmeriaefolii, Ramulus et Folium Psychotriae Serpentis, Radix Impatientis, Acer mono Maxim., Radix Morindae Officinalis, Rhizoma seu Herba Elatostematis stewardii, Cortex araliae chinensis, red, the Herba Blumeae Laciniatae of snowing, Herba Pyrolae, Cortex Aceris Sinensis, Semen Astragali Complanati, thunderclap pasture and water, Fructus Canarii Pimelae, Isodon ternifolius be that raw material is prepared from.Its component (weight portion) is every secondary is Carapax et Plastrum Testudinis 7, little Lycopodium clavatum 6, Herba Epimedii 6, Caulis Piperis Boehmeriaefolii 5, Ramulus et Folium Psychotriae Serpentis 6, Radix Impatientis 6, Acer mono Maxim. 7, Radix Morindae Officinalis 7, Rhizoma seu Herba Elatostematis stewardii 8, Cortex araliae chinensis 7, red 4, the Herba Blumeae Laciniatae 8 of snowing, Herba Pyrolae 3, Cortex Aceris Sinensis 5, Semen Astragali Complanati 3, thunderclap pasture and water 5, Fructus Canarii Pimelae 3, Isodon ternifolius 8.Get above-mentioned 18 taste raw materials, gross weight is 176 grams, add water 800 ~ 900 milliliters and at room temperature soak 5 ~ 6 hours, slow fire decocted to 60 ~ 80 minutes, filtrate about 150 milliliters of removing slag to obtain, and medicinal residues add water 200 ~ 300ml again, decoct 20 ~ 30 minutes, to remove slag to obtain filtrate 50 ~ 70 milliliters, altogether the medicine juice of about 200 ~ 220 milliliters, i.e. obtained decoction of the present invention.Load in sterile glass vials, seal bottle cap is for subsequent use, and every day 1 dose point 2 times is oral, sooner or later respectively once, and each (medicine) being taken before meal 100 ~ 110 milliliters.
Carapax et Plastrum Testudinis YIN nourishing of the present invention, YANG hyperactivity suppressing, the kidney invigorating, strong bone; Little Lycopodium clavatum expelling wind and removing dampness, dredge the meridian passage, reducing swelling and alleviating pain.Main lumbago, skelalgia of rheumatism, arthralgia, traumatic injury; Herba Epimedii controls sexual impotence erectile problem, dribbling urination, and muscles and bones contraction is anxious; Caulis Piperis Boehmeriaefolii cures mainly: cold, rheumatic arthralgia, traumatic injury, fracture; Ramulus et Folium Psychotriae Serpentis wind-damp dispelling, strengthening bone and muscle, pain relieving, detumescence; Radix Impatientis is invigorated blood circulation, and stimulates the menstrual flow, softening the hard mass, detumescence.Dispelling the wind and dampness pathogens bones and muscles pain, tumbling and swelling; Acer mono Maxim. expelling wind and removing dampness, promoting blood circulation and stopping pain.Main migraine and general headache, anemofrigid-damp arthralgia, traumatic injury stasis of blood pain; Radix Morindae Officinalis cures mainly that impotence and seminal emission, cold womb are infertile, menoxenia, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity are soft; Rhizoma seu Herba Elatostematis stewardii promoting blood circulation to remove blood stasis, detumescence cough-relieving.Control osteopatia sprain, mumps, amenorrhea, cough; Cortex araliae chinensis cures mainly: rheumatic arthritis, waist and leg ache, and edema due to deficiency of the kidney is quenched one's thirst, traumatic injury, fracture; Snow red promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.Cure mainly treating swelling and pain by traumatic injury; The Herba Blumeae Laciniatae is used for rheumatic ostalgia, headache, treating swelling and pain by traumatic injury, the disease such as eczema and venom; Herba Pyrolae wind-damp dispelling, bone and muscle strengthening, hemostasis.For rheumatic arthralgia, weakness of the waist and knees; Cortex Aceris Sinensis expelling wind and removing dampness, controls arthralgia, fracture; Thunderclap pasture and water tonify deficiency, dehumidifying, relaxing muscles and tendons and activating QI and blood in the collateral.Control deficiency-heat not move back, oedema due to nephritis, rheumatic arthralgia; Semen Astragali Complanati has the effect of tonifying the kidney to consolidate the essence, liver heat removing and eyesight improving, cures mainly soreness of waist and knee joint; Fructus Canarii Pimelae relaxing muscles and tendons and activating QI and blood in the collateral, damp eliminating of dispeling the wind.For lumbago, skelalgia of rheumatism, numb hand and foot; Isodon ternifolius controls dysentery enteritis, pharyngolaryngitis, tonsillitis, urinary tract infection, cystitis, acute nephritis, swelling pain.
The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize.Its processing technique is identical with embodiment 1.
The clinical trial carried out below in conjunction with my institute is done further the present invention, is described in detail:
The Criteria of Osteoporosis of doctor trained in Western medicine is with reference to " diagnostic criteria of primary osteoporosis for Chinese people (trying) ", according to international diagnostic criteria, simultaneously in conjunction with Chinese feature, according to bone density lower than agnate, same to sex, deduct two standard deviations (-2.0SD) with position Healthy People peak bone mass bone amount meansigma methods, osteoporosis can be diagnosed as.
In 114 routine patients with primary osteoporosis, man 62 example, female 52 example, age 52-73 year, 55 years old mean age, average course of disease 7.1 years, all patients all do not suffer from the disease such as rheumatism, endocrine, immunity affecting bone metabolism.114 patients are divided into 2 groups at random, and two groups of no significant difference (P > 0.05), have comparability.
Treatment group: 57 people, male 30 people, female 27 people; Take embodiment one medicament, every day 1 dose point 2 times is oral, sooner or later each once, each (medicine) being taken before meal 100 ~ 110 milliliters 1 month is a course for the treatment of.
Matched group: 57 people, male 32 people, female 25 people; Oral alfacalcidol soft capsule 0.5 μ g (2), 1 time on the one; Oral calcium gluconate oral administration solution one time 1,3 times on the one; Oral clodronic acid disodium, 1.6g/ day, takes at twice, entering diet front and rear 2 hours, takes between meal, within 1 month, is a course for the treatment of.
Adopt Study of bone mineral density instrument (DEXA), measure the left forearm overall bone density of far-end 1/3 radius (g/cm2).
Osteoporosis efficacy assessment standard:
The observation of clinical cardinal symptom is with reference to Chinese's osteoporosis suggestion diagnostic criteria.
Effective: lumbar and back pain disappears substantially, functional activity is normal.
Effective: lumbar and back pain alleviates, functional activity is normal.
Invalid: lumbar and back pain does not alleviate, functional activity does not improve
Therapeutic outcome:
See table 1, as can be seen from Table 1, adopt treatment by Chinese herbs osteoporosis of the present invention, relative to matched group on therapeutic effect, there is significant improvement.
A table 1 liang group treats Clinical efficacy comparison example (%) after 2 months respectively
Table 2 liang group treats the change (g/cm2) of BMD value before and after treatment after 2 months respectively
From table 2 to find out, adopt Drug therapy osteoporosis of the present invention, relative to matched group on therapeutic effect, there is significant improvement.After adopting Drug therapy osteoporosis therapy of the present invention, BMD value significantly improves, and improvement degree is obviously better than matched group.
Model case: patient paddy, man, 65 years old, because lumbago is gone to a doctor, forgetful, tongue is thin, thready pulse without strength, with alopecia tooth pine, Hiccough and deaf, soreness of the waist and knees, through health check-up and kidney function test no abnormality seen, x-ray inspection shows: tubular bone cortex is thinning, pulp cavity broadens, bone trabecula decreased number, its gap is also broadening, is diagnosed as osteoporosis.Take embodiment one medicament, every day 1 dose point 2 times is oral, sooner or later each once, each (medicine) being taken before meal 100 ~ 110 milliliters, treat lumbar and back pain after 1 month and alleviate, functional activity is normal, and treat lumbar and back pain after 2 months and substantially disappear, functional activity is normal.
Claims (1)
1. the osteoporotic medicine for the treatment of, it is characterized in that being made up of the crude drug of following weight portion: Carapax et Plastrum Testudinis 5 ~ 9, little Lycopodium clavatum 4 ~ 7, Herba Epimedii 4 ~ 8, Caulis Piperis Boehmeriaefolii 4 ~ 7, Ramulus et Folium Psychotriae Serpentis 4 ~ 8, Radix Impatientis 5 ~ 8, Acer mono Maxim. 6 ~ 9, Radix Morindae Officinalis 6 ~ 9, Rhizoma seu Herba Elatostematis stewardii 7 ~ 9, Cortex araliae chinensis 6 ~ 9, red 2 ~ 5, the Herba Blumeae Laciniatae 6 ~ 9 of snowing, Herba Pyrolae 2 ~ 5, Cortex Aceris Sinensis 4 ~ 6, Semen Astragali Complanati 2 ~ 4, thunderclap pasture and water 4 ~ 6, Fructus Canarii Pimelae 2 ~ 4, Isodon ternifolius 7 ~ 9, by medicinal for above-mentioned raw materials water soaking, filtrate of removing slag after decocting to obtain.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510560675.6A CN105079184A (en) | 2015-08-26 | 2015-08-26 | Medicine for treating osteoporosis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510560675.6A CN105079184A (en) | 2015-08-26 | 2015-08-26 | Medicine for treating osteoporosis |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105079184A true CN105079184A (en) | 2015-11-25 |
Family
ID=54561113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510560675.6A Pending CN105079184A (en) | 2015-08-26 | 2015-08-26 | Medicine for treating osteoporosis |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105079184A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106266351A (en) * | 2016-11-07 | 2017-01-04 | 成都泠汐尚品科技有限公司 | One is used for treating osteoporotic Chinese medicine formula |
CN107349363A (en) * | 2017-07-14 | 2017-11-17 | 庄乾东 | A kind of Chinese medicine preparation for treating osteoporosis and preparation method thereof |
CN107496885A (en) * | 2017-09-29 | 2017-12-22 | 南京仙草堂生物科技有限公司 | A kind of preparation method for the dendrobium candidum Chinese medicine preparation for treating osteoporosis |
CN107569668A (en) * | 2017-09-29 | 2018-01-12 | 南京仙草堂生物科技有限公司 | A kind of dendrobium candidum Chinese medicine preparation for treating osteoporosis |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1879846A (en) * | 2006-04-30 | 2006-12-20 | 桂林天和药业股份有限公司 | A Chinese medicinal preparation for treating rheumatism, hyperosteogeny and osteoporosis and method for preparing same |
-
2015
- 2015-08-26 CN CN201510560675.6A patent/CN105079184A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1879846A (en) * | 2006-04-30 | 2006-12-20 | 桂林天和药业股份有限公司 | A Chinese medicinal preparation for treating rheumatism, hyperosteogeny and osteoporosis and method for preparing same |
Non-Patent Citations (2)
Title |
---|
杨茂伟等: "金乌骨通胶囊治疗骨质疏松67例临床观察", 《中国骨质疏松杂志》 * |
胡荫奇等: "《简明中西医结合风湿病学》", 28 February 2009, 科学技术文献出版社 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106266351A (en) * | 2016-11-07 | 2017-01-04 | 成都泠汐尚品科技有限公司 | One is used for treating osteoporotic Chinese medicine formula |
CN107349363A (en) * | 2017-07-14 | 2017-11-17 | 庄乾东 | A kind of Chinese medicine preparation for treating osteoporosis and preparation method thereof |
CN107496885A (en) * | 2017-09-29 | 2017-12-22 | 南京仙草堂生物科技有限公司 | A kind of preparation method for the dendrobium candidum Chinese medicine preparation for treating osteoporosis |
CN107569668A (en) * | 2017-09-29 | 2018-01-12 | 南京仙草堂生物科技有限公司 | A kind of dendrobium candidum Chinese medicine preparation for treating osteoporosis |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102988657A (en) | Plaster for treating fracture and traumatic injury and preparation method of plaster | |
CN104189871A (en) | Medicated wine for treating osteoproliferation | |
CN105079184A (en) | Medicine for treating osteoporosis | |
CN103520579A (en) | Medicinal liquor used for treating lumbocrural pain, hyperostosis and sciatica | |
CN102626505B (en) | Massaging paste based on Chinese medicinal herbs and preparation method thereof | |
CN102247497A (en) | Chinese patent medicine for treating rheumatoid arthritis | |
CN103784804A (en) | Pharmaceutical composition for treating benign prostatic hyperplasia | |
CN104857311A (en) | Traditional Chinese medicine for treating ischemic necrosis of femoral head | |
CN104306606A (en) | A traditional Chinese medicine preparation for treating osteoarthritis and a preparing method thereof | |
CN103784824A (en) | Chinese herbal preparation for treating lumbar disc herniation and rheumatoid | |
CN103495085A (en) | Traditional Chinese medicine preparation for treating radiodermatitis | |
CN112755169A (en) | Traditional Chinese medicine plaster for treating rheumatic ostealgia | |
CN101972321A (en) | Plaster for treating pains on neck, shoulder, lumbar and legs as well as traumatic injuries | |
CN104258308A (en) | Traditional Chinese medicine preparation for treating cholelithiasis | |
CN104383175A (en) | Medicine for treating chronic osteomyelitis and preparation method of medicine | |
CN104800443A (en) | Bone setting agent with functions of tonifying kidney and regenerating bone marrow | |
CN104758525A (en) | Traditional Chinese medicine composition for treating primary dysmenorrhea in the type of cold-dampness coagulation | |
CN111265644A (en) | Bone-activating pain-relieving plaster and preparation method thereof | |
CN101954043A (en) | Medicament for treating hyperosteogeny and preparation method thereof | |
CN102028810B (en) | Traditional Chinese medicine for treating lumbar intervertebral disc protrusion | |
CN102430066B (en) | Sciatic nerve liquid | |
CN105456538A (en) | Drug for treating osteoporosis | |
CN105560610A (en) | Traditional Chinese medicine for treating bone fracture and preparation method | |
CN104815132A (en) | External lotion for treating low back and leg pain and preparation method | |
CN104491255A (en) | Traditional Chinese medicine preparation for treating acute cholecystitis |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151125 |