CN111265644A - Bone-activating pain-relieving plaster and preparation method thereof - Google Patents

Abstract

The invention relates to a bone-activating analgesic plaster and its preparation method, the plaster is prepared from earthworm, trogopterus dung, radix Linderae, Clematis chinensis, herba Aristolochiae, rhizoma Atractylodis, Angelica sinensis, rhizoma Et radix Notopterygii, flos Carthami, radix Angelicae Dahuricae, radix Saposhnikoviae, Olibanum, Myrrha, herba speranskiae tuberculatae, rhizoma Zingiberis, Os Canitis, radix Paeoniae alba, herba asari, rhizoma Chuanxiong, radix Notoginseng, caulis Piperis Kadsurae, caulis Lonicerae, herba Aristolochiae Mollissimae, radix scrophulariae, squama Manis, rhizoma Curcumae, radix Glycyrrhizae, rhizoma corydalis Preparata, herba Menthae, flos Caryophylli, radix Cyathulae, and cortex Eucommiae Preparata by rational compatibility, scientific ratio; the plaster prepared by the invention has the effects of warming and activating meridian, diminishing inflammation and relieving pain, softening hardness and resolving hard mass, promoting blood circulation and removing blood stasis, and dispelling wind and eliminating dampness; the elastic regeneration of activated fibrous tissues can be improved, the pressed tissues can be relaxed, qi and blood can smoothly flow, and pain can be eliminated; has remarkable curative effect on cervical spondylosis, lumbar spondylosis, lower limb joint pain, tenosynovitis, tennis elbow and old bone injury patients, and does not relapse.

Description

Bone-activating pain-relieving plaster and preparation method thereof

Technical Field

The invention relates to a plaster, in particular to a plaster for activating bone and relieving pain and a preparation method thereof.

Background

Bone injury is roughly divided into mechanical trauma, invasion of cold evil, disturbance of wind evil and the like, and the more serious the trauma is, the more severe the pain is. Post-traumatic pain is a reaction to aseptic inflammation of soft tissues, resulting from the stimulation of nerve endings by the chemical substances produced. Therefore, muscle and small vessel spasm, blood supply insufficiency of soft tissues, metabolism and nutrition disorder can be reflexively caused, even inflammatory fiber adhesion or inflammatory tissue hyperplasia occurs, the contracture soft tissues compress small vessels and nerve endings, and regular pressure pain points of specific parts appear clinically.

The traditional Chinese medicine considers that the body is wounded and swollen, and the qi is wounded and painful. The obstruction of channels and collaterals due to injury of bone and tendon can lead to stagnation of qi and blood, and pain caused by obstruction. The patient is easy to have the problems of emotional dysphoria, anxiety, increased body temperature, nausea and vomiting, accelerated heart rate and the like due to pain and limited motor function, and can induce other diseases or aggravate the original diseases.

At present, the medicines for treating bone injury pain are various, such as oral analgesic medicines and some hormone medicines for injection, although oral medicines can play a certain role in relieving pain, the effect of radically treating diseases is difficult to achieve, and gastrointestinal tracts are easy to be stimulated by long-term administration, so that the medicines are not easy to be taken by patients with stomach diseases; the injection of the medicine can only temporarily inhibit the disease development, the patient can not be cured, and the long-term injection of the hormone can cause great harm to the human body. In contrast, various topical plasters are popular with patients. Chinese patent CN107496865A discloses a rheumatalgia plaster, which is prepared from the following medicinal materials in parts by weight: 15-20 parts of pubescent angelica root, 13-16 parts of feverfew, 13-16 parts of obscured homalomena rhizome, 10-13 parts of kadsura pepper stem, 10-13 parts of asarum, 9-12 parts of sarcandra glabra, 13-16 parts of cinnamon, 5-7 parts of dried ginger and 4-6 parts of borneol; and provides a preparation method thereof. Chinese patent CN105079583A discloses a plaster for treating ostealgia, which comprises the following components in parts by weight: 90-110 parts of raw rhubarb, 50-70 parts of salvia miltiorrhiza, 50-70 parts of safflower, 30-50 parts of corydalis tuber, 8-12 parts of borneol, 90-110 parts of hibiscus leaves, 15-25 parts of tortoise shell and 40-60 parts of rice straw ash. The existing plaster has too simple formula, is difficult to achieve scientific formula of complex pain etiology, and has the disadvantages of too large particle size, difficult medicine effect reaching focus and common treatment effect by adding the traditional Chinese medicine grinding method.

Disclosure of Invention

Aiming at the defects of the prior art, the invention aims to provide the bone-activating pain-relieving plaster which has the effects of warming and activating meridian, diminishing inflammation and relieving pain, softening hardness and resolving hard mass, promoting blood circulation to remove blood stasis, and dispelling wind and removing dampness, and has obvious curative effects on cervical spondylosis, lumbar spondylosis, lower limb arthralgia, tenosynovitis, tennis elbow and old bone fracture patients.

In order to achieve the purpose, the invention adopts the following technical scheme:

the plaster for activating bone and relieving pain is prepared from the following raw materials in parts by weight: 10-25 parts of earthworm, 15-20 parts of trogopterus dung, 10-15 parts of combined spicebush root, 20-30 parts of clematis root, 15-30 parts of Japanese tussah vine, 10-20 parts of rhizoma atractylodis, 10-20 parts of angelica, 15-30 parts of notopterygium root, 30-40 parts of safflower, 20-30 parts of angelica dahurica, 15-25 parts of divaricate saposhnikovia root, 10-15 parts of frankincense, 10-15 parts of myrrh, 30-40 parts of garden balsam stem, 30-50 parts of dried ginger, 15-20 parts of dog bone, 20-30 parts of white paeony root, 20-30 parts of asarum, 20-30 parts of szechuan lovage rhizome, 30-50 parts of pseudo-ginseng, 20-25 parts of kadsura pepper stem, 20-25 parts of honeysuckle stem, 30-35 parts of wooly mollissima, 15-30 parts of figwort root, 15-20 parts of stir-baked pan, 15-30 parts of mint, 20-25 parts of clove, 30-50 parts of medicinal cyathula root, 20-35 parts of fried eucommia bark, 1200 parts of yellow lead and 1500 parts of red sage root, and 1800 parts of vegetable oil and 2200 parts of sand-broken sage root.

Preferably, the plaster is prepared from the following raw materials in parts by weight: 15-20 parts of earthworm, 16-18 parts of trogopterus dung, 12-13 parts of combined spicebush root, 22-28 parts of clematis root, 20-25 parts of henbane stem, 12-18 parts of rhizoma atractylodis, 12-18 parts of angelica, 20-25 parts of notopterygium root, 32-38 parts of safflower, 22-28 parts of angelica dahurica, 18-22 parts of divaricate saposhnikovia root, 12-14 parts of frankincense, 11-14 parts of myrrh, 32-38 parts of garden balsam stem, 35-45 parts of dried ginger, 16-18 parts of dog bone, 22-28 parts of white peony root, 22-28 parts of asarum, 22-26 parts of szechuan lovage rhizome, 35-45 parts of pseudo-ginseng, 21-24 parts of kadsura pepper stem, 22-24 parts of honeysuckle stem, 32-34 parts of wooly mollissima, 20-25 parts of figwort root, 16-18 parts of stir-baked pangolin scales, 20-25 parts of mint, 22-24 parts of clove, 35-45 parts of medicinal cyathula root, 25-30 parts of fried eucommia bark, 1300 parts of yellow lead and 1400 parts of vegetable oil and 1900 parts of tea.

Preferably, the plaster is prepared from the following raw materials in parts by weight: 18 parts of earthworm, 17 parts of trogopterus dung, 12.5 parts of combined spicebush root, 25 parts of clematis root, 22 parts of henbane stem, 15 parts of rhizoma atractylodis, 15 parts of angelica, 22 parts of notopterygium root, 35 parts of safflower, 25 parts of angelica dahurica, 20 parts of divaricate saposhnikovia root, 13 parts of frankincense, 12.5 parts of myrrh, 35 parts of garden balsam stem, 40 parts of dried ginger, 17 parts of dog bone, 25 parts of white paeony root, 25 parts of asarum, 24 parts of szechuan lovage rhizome, 40 parts of pseudo-ginseng, 22.5 parts of kadsura pepper stem, 23 parts of honeysuckle stem, 33 parts of wooly datchmanspipe herb, 22.5 parts of figwort root, 17 parts of pangolin scales, 40 parts of zedoary, 22.5 parts of liquorice, 27 parts of vinegar rhizoma corydalis, 22.5 parts of mint.

Preferably, the vegetable oil is one of sesame oil, cottonseed oil, rapeseed oil and peanut oil.

On the other hand, the invention also provides a preparation method of the bone-activating pain-relieving plaster, which comprises the following steps:

(1) weighing the raw materials according to a formula, mixing and drying earthworm, trogopterus dung, combined spicebush root, clematis root, Japanese dutchmanspipe stem, rhizoma atractylodis, Chinese angelica, notopterygium root, safflower, angelica dahurica, divaricate saposhnikovia root, frankincense, myrrh, garden balsam stem, dried ginger, dog bone, white paeony root, manchurian wildginger, szechuan lovage rhizome, pseudo-ginseng, kadsura pepper stem, honeysuckle stem, berba aristolochiae mollissimae, figwort root, stir-baked pangolin scales, zedoary, liquorice, vinegar rhizoma corydalis, mint, clove, medicinal cyathula root and stir-fried eucommia bark, crushing into 1000-fold-powder with a wall;

(2) parching Plumbum Preparatium with slow fire until water and gas in the pill are dispersed completely, and cooling;

(3) putting the vegetable oil into a pot, boiling with strong fire for 10-15 minutes, then decocting with slow fire for 45-60 minutes, slowly adding the fried yellow lead obtained in the step (2) into the vegetable oil pot, stirring while adding, slowly adding the traditional Chinese medicine mixed powder obtained in the step (1) into the vegetable oil pot after the vegetable oil is slightly cold, uniformly stirring, and finally pouring the plaster on kraft paper or special plaster cloth to obtain the plaster.

The traditional Chinese medicine used by the invention has the following medicinal properties:

earthworm: cold in nature, salty in taste; enter intestines, stomach and kidney meridians. Has effects in clearing away heat, relieving spasm, promoting urination, and removing toxic materials. Can be used for treating febrile convulsion, rheumatic arthritis, hemiplegia, infantile convulsion, and urinary dysfunction; erysipelas dermatitis is externally applied.

Trogopterus dung: warm in nature, salty and sweet in taste. It enters liver meridian. Has effects in promoting blood circulation, relieving pain, removing blood stasis, stopping bleeding, and removing food stagnation. It can be used for treating blood and qi pain of heart and abdomen, amenorrhea, puerperal abdominal pain due to blood stasis, metrorrhagia, metrostaxis, and infantile malnutrition; it can be used for treating snake bite, scorpion bite, and centipede bite.

Combined spicebush root: warm in nature and pungent in flavor. It enters lung meridian, spleen meridian, kidney meridian and bladder meridian. Has effects in regulating qi, relieving depression, dispelling cold, and relieving pain. It can be used for treating abdominal distention and pain due to adverse qi, indigestion, regurgitation, vomiting, cold hernia, etc.

Clematis root: warm in nature, pungent and salty in flavor. It enters bladder meridian. Has effects of dispelling pathogenic wind, eliminating dampness, activating qi-flowing and dredging collaterals. It can be used for treating rheumatic arthralgia, paralysis, and numbness.

Caulis aristolochiae: warm in nature and bitter in taste. It enters liver, spleen and kidney meridians. Has effects of activating qi-flowing, promoting blood circulation, inducing diuresis, and relieving swelling. Can be used for treating abdominal pain, arthralgia, and edema during pregnancy.

Rhizoma atractylodis: warm in nature, pungent and bitter in flavor. It enters spleen, stomach and liver meridians. Has effects of eliminating dampness, invigorating spleen, dispelling pathogenic wind, dispelling cold, and improving eyesight. It can be used for treating abdominal distention, diarrhea, edema, tinea pedis, and rheumatic arthralgia.

Chinese angelica: warm in nature, sweet and pungent in flavor. It enters liver meridian, heart meridian and spleen meridian. Has effects in replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation. It can be used for treating rheumatic arthralgia, traumatic injury, superficial infection, pyocutaneous disease, etc.

Notopterygium root: warm in nature, pungent and bitter in flavor. It enters bladder meridian and kidney meridian. Has effects in relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, removing dampness, and relieving pain. It can be used for treating wind-cold type common cold, headache, stiff neck, rheumatalgia, and soreness of shoulder and back.

Safflower: warm in nature and pungent in flavor. It enters heart and liver meridians. Has effects in promoting blood circulation, dredging channels, removing blood stasis, and relieving pain. It can be used for treating abdominal mass, traumatic injury, pyocutaneous disease, swelling and pain.

Radix angelicae: warm in nature and pungent in flavor. It enters stomach meridian, large intestine meridian and lung meridian. Has effects in dispelling pathogenic wind, removing dampness, inducing resuscitation, relieving pain, relieving swelling, and expelling pus. Can be used for treating supraorbital pain, nasal obstruction, nasosinusitis, toothache, leukorrhagia, and pyocutaneous disease with swelling and pain.

Wind prevention: warm in nature, sweet and pungent in flavor. It enters bladder meridian, liver meridian and spleen meridian. Has effects of relieving exterior syndrome, dispelling pathogenic wind, and eliminating dampness. Can be used for treating rheumatic arthralgia, spasm of limbs, skin pruritus due to rheumatism, and tetanus.

Frankincense: warm in nature, pungent and bitter in flavor. They enter heart, spleen and liver meridians. Has effects in regulating qi, promoting blood circulation, relieving pain, eliminating swelling, and promoting granulation. Can be used for treating stagnation of qi and blood, pain of heart and abdomen, carbuncle, sore, toxic swelling, traumatic injury, and rheumatalgia.

Myrrh: mild in nature, bitter and pungent in flavor. It enters liver meridian. Has effects of dispelling blood stasis, relieving pain, eliminating swelling, and promoting granulation. It is indicated for abscess, deep-rooted carbuncle, swelling and pain, pain of heart, abdomen, tendons and bones, blood injury, wound healing and tissue regeneration.

Garden balsam stem: warm in nature and pungent in flavor. Has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles, promoting blood circulation, and relieving pain. It can be used for treating rheumatic arthralgia, contracture of bones and muscles, tinea pedis due to cold-dampness, skin sore, tinea, and toxic swelling.

Dried ginger: warm in nature and pungent in flavor. It enters spleen, stomach and lung meridians. Has the effects of warming middle-jiao, expelling cold, restoring yang and dredging collaterals. It can be used for treating psychroalgia of heart and abdomen, emesis, diarrhea, cold limbs, slight pulse, cough and asthma due to cold, arthralgia due to wind-cold-dampness, emesis due to yang deficiency, epistaxis, and hematochezia.

Dog bones: warm in nature, pungent and salty in flavor. Has effects of invigorating spleen, regulating meridians, promoting blood circulation, and promoting granulation. Can be used for treating rheumatalgia, weakness of waist and legs, numbness of limbs, chronic dysentery, sore and fistula, and chilblain.

White peony root: mild in nature and bitter in taste. It enters liver and spleen meridians. Has the effects of nourishing blood, softening liver, relieving pain, astringing yin and arresting sweating. It can be used for treating chest, abdomen, hypochondriac pain, dysentery, abdominal pain, spontaneous perspiration, night sweat, fever due to yin deficiency, menoxenia, metrorrhagia, and leukorrhagia.

Asarum: warm in nature and pungent in flavor. It enters lung and kidney meridians. Has effects of dispelling cold, relieving exterior syndrome, dispelling pathogenic wind and relieving pain. It can be used for treating rheumatalgia, and pain due to wind-cold.

Ligusticum wallichii: warm in nature and pungent in flavor. It enters liver, gallbladder and pericardium meridians. Has effects of promoting blood circulation, activating qi-flowing, dispelling pathogenic wind and relieving pain. It can be used for treating wind-cold headache, dizziness, hypochondriac pain, abdominal pain, arthralgia due to cold, spasm of tendons, and traumatic injury with swelling and pain.

Pseudo-ginseng: warm in nature, sweet and slightly bitter in taste. It enters liver and stomach meridians. Has effects of stopping bleeding, removing blood stasis, and relieving swelling and bleeding. It can be used for treating traumatic swelling, pain, hemorrhage, dysentery, metrorrhagia, puerperal abdominal pain due to blood stasis, carbuncle, swelling, and sore.

Caulis piperis futokadsurae: slightly warm in nature and pungent in flavor. It enters liver meridian. Has effects of dispelling pathogenic wind, removing dampness, relieving rigidity of muscles and activating collaterals. Can be used for treating rheumatic arthritis, lumbago, skelalgia, lumbar muscle strain, spasm of muscles and tendons, and puerperal paralysis.

Honeysuckle stem: cold in nature and sweet in taste. It enters stomach and liver meridians. Has the effects of clearing away heat and toxic materials, and relieving arthralgia and dredging channels. It is mainly used for treating rheumatic arthralgia, difficulty in flexion and extension of joints, etc.

Herba Aristolochiae Mollissimae: mild in nature, pungent and bitter in flavor. It enters liver meridian and stomach meridian. Has effects of dispelling pathogenic wind, dredging collaterals, activating qi-flowing and relieving pain. Can be used for treating rheumatic arthralgia, numbness of limbs, spasm of muscles and bones, and pain due to traumatic injury.

Figwort root: slightly cold in nature, sweet, bitter and salty in taste. It enters lung meridian, stomach meridian and kidney meridian. Has effects in cooling blood, nourishing yin, purging pathogenic fire, and removing toxic substance. It can be used for treating yin injury due to febrile disease, polydipsia, warm toxicity, macula, constipation due to body fluid consumption, etc.

Processing pangolin scales: has effects in relieving swelling and suppuration, dispelling blood stasis, dredging meridians, promoting lactation, promoting blood circulation, and relieving pain. It can be used for treating carbuncle, cellulitis, sore, arthralgia due to wind-cold-dampness, amenorrhea, galactostasis, hemostasis, and eschar accumulation.

Zedoary turmeric: warm in nature, pungent and bitter in flavor. It enters spleen and liver meridians. Has effects of activating qi-flowing, removing blood stasis, resolving food stagnation and relieving pain. Can be used for treating amenorrhea due to blood stasis, food stagnation, distending pain, and early stage cervical cancer.

Licorice root: mild in nature and sweet in taste. They enter heart, stomach, spleen and lung meridians. Has effects of invigorating spleen and qi, relieving cough and eliminating phlegm, relieving spasm and relieving pain, and harmonizing drug property.

Vinegar Yanhu: warm in nature, pungent and bitter in flavor. It enters liver, stomach and heart meridians. Has effects in promoting blood circulation, activating qi-flowing, and relieving pain. Can be used for treating thoracic obstruction, cardialgia, gastralgia, hypochondriac distention and pain due to stagnation of qi due to depression of the liver, dysmenorrhea, puerperal abdominal pain due to stagnation, hernia of cold type, traumatic injury, and rheumatalgia.

Mint: cool in nature and pungent in flavor. It enters lung and liver meridians. Has effects of dispelling pathogenic wind heat, refreshing head, and promoting eruption. It can be used for treating skin pruritus and measles without adequate eruption.

Clove: pungent flavor and warm nature. It enters stomach, spleen and kidney meridians. Has effects of warming middle-jiao, lowering adverse qi, invigorating kidney, and tonifying yang.

Radix cyathulae: mild in nature, sweet and slightly bitter in taste. It enters liver and kidney meridians. Has effects of removing blood stasis, dredging channels, promoting joint movement, and inducing diuresis for treating stranguria. Can be used for treating rheumatic lumbago, gonalgia, foot flaccidity, spasm of tendons, stranguria with blood, and stranguria with urine.

Parching eucommia ulmoides: warm in nature and sweet in taste. Has effects in tonifying liver and kidney, strengthening muscle and bone, regulating Chong and ren meridians, and preventing miscarriage.

The drug effect of the traditional Chinese medicine used in the invention is summarized as follows:

the medicine has the effects of dispelling wind, eliminating dampness, warming channels and dredging collaterals: earthworm, trogopterus dung, combined spicebush root, Japanese Aristolochia, rhizoma atractylodis, Chinese angelica, notopterygium root, safflower, angelica dahurica, divaricate saposhnikovia root, frankincense, myrrh, garden balsam stem, dried ginger, dog bone, white paeony root and liquorice.

The medicine with the functions of diminishing inflammation and relieving pain comprises the following components: caulis Piperis Futokadsurae, caulis Lonicerae, and herba Aristolochiae Mollissimae.

The medicine with the effect of softening hard masses and resolving hard masses: radix Cyathulae, parched Eucommiae cortex, radix Clematidis, radix scrophulariae, and squama Manis.

The medicine with the efficacy of promoting blood circulation and removing blood stasis: notoginseng, chuanxiong rhizome, zedoary, vinegar-soaked corydalis root.

The medicine with the effect of walking channels and collaterals: clove, mint and asarum.

Compared with the prior art, the invention has the following beneficial effects:

(1) the plaster is prepared by reasonably matching 32 traditional Chinese medicines and scientifically proportioning, and has the effects of warming and activating meridian, diminishing inflammation and relieving pain, softening hardness and resolving masses, promoting blood circulation to remove blood stasis, and dispelling wind and eliminating dampness; the elastic regeneration of activated fibrous tissues can be improved, the pressed tissues can be relaxed, qi and blood can smoothly flow, and pain can be eliminated; has remarkable curative effect on cervical spondylosis, lumbar spondylosis, lower limb joint pain, tenosynovitis, tennis elbow and old bone injury patients, and does not relapse.

(2) According to the invention, the traditional Chinese medicines in the formula are subjected to wall breaking and crushing treatment, so that each medicine particle is close to the pore diameter of epidermal tissue pores, and the medicine can better penetrate through skin to reach a focus, and can treat both principal and secondary aspects of diseases.

(3) The plaster is convenient to use, safe, reliable, free of toxic and side effects and wide in applicable population.

Detailed Description

The invention is further illustrated by the following specific examples:

example 1

(1) Weighing the raw materials according to a formula, mixing and drying 18 parts of earthworm, 17 parts of trogopterus dung, 12.5 parts of radix linderae, 25 parts of radix clematidis, 22 parts of herba aristolochiae, 15 parts of rhizoma atractylodis, 15 parts of angelica sinensis, 22 parts of notopterygium root, 35 parts of safflower, 25 parts of radix angelicae, 20 parts of radix sileris, 13 parts of frankincense, 12.5 parts of myrrh, 35 parts of garden balsam stem, 40 parts of dried ginger, 17 parts of dog bone, 25 parts of radix paeoniae alba, 25 parts of asarum, 24 parts of ligusticum wallichii, 40 parts of pseudo-ginseng, 22.5 parts of futokadsura stem, 23 parts of honeysuckle stem, 33 parts of wooly datchmanspipe, 22.5 parts of radix scrophulariae, 17 parts of stir-baked squama manitis, 40 parts of curcuma zedoary, 22.5 parts of liquorice, 27 parts of vinegar rhizoma corydalis, 22.5 parts of mint, 23 parts of clove, 40 parts of medicinal cyathula root and;

(2) frying 1350 parts of yellow lead with slow fire until the water in the lead is dispersed completely, and cooling for later use;

(3) putting 2000 parts of vegetable oil into a pot, boiling with strong fire for 12 minutes, then decocting with slow fire for 52 minutes, slowly adding the fried yellow lead obtained in the step (2) into the vegetable oil pot while stirring, slowly adding the Chinese medicinal mixed powder obtained in the step (1) into the vegetable oil pot after the vegetable oil is slightly cold, uniformly stirring, and finally pouring the plaster on kraft paper or special plaster cloth to obtain the plaster.

Example 2

(1) Weighing the raw materials according to a formula, mixing and drying 10 parts of earthworm, 15 parts of trogopterus dung, 10 parts of radix linderae, 20 parts of radix clematidis, 15 parts of herba aristolochiae, 10 parts of rhizoma atractylodis, 10 parts of angelica sinensis, 15 parts of notopterygium root, 30 parts of safflower, 20 parts of radix angelicae, 15 parts of radix sileris, 10 parts of frankincense, 10 parts of myrrh, 30 parts of garden balsam stem, 30 parts of dried ginger, 15 parts of dog bone, 20 parts of white paeony root, 20 parts of asarum, 20 parts of ligusticum wallichii, 30 parts of pseudo-ginseng, 20 parts of kadsura pepper stem, 20 parts of honeysuckle stem, 30 parts of mollissimae, 15 parts of radix scrophulariae, 15 parts of stir-baked squama manitis, 30 parts of rhizoma zedoariae, 15 parts of liquorice, 25 parts of vinegar rhizoma corydalis, 15 parts of mint, 20 parts of clove, 30 parts of radix cyathulae and 20 parts of fried;

(2) parching 1200 parts of yellow lead with slow fire until the water in the lead is dispersed completely, and cooling for later use;

(3) putting 1800 parts of vegetable oil into a pot, boiling with strong fire for 10 minutes, then decocting with slow fire for 45 minutes, slowly adding the fried yellow lead obtained in the step (2) into the vegetable oil pot while stirring, slowly adding the traditional Chinese medicine mixed powder obtained in the step (1) into the vegetable oil pot after the vegetable oil is slightly cold, uniformly stirring, and finally pouring the plaster on kraft paper or special plaster cloth to obtain the plaster.

Example 3

(1) Weighing the raw materials according to a formula, mixing and drying 25 parts of earthworm, 20 parts of trogopterus dung, 15 parts of combined spicebush root, 30 parts of clematis root, 30 parts of Japanese tussah, 20 parts of rhizoma atractylodis, 20 parts of angelica, 30 parts of notopterygium root, 40 parts of safflower, 30 parts of angelica dahurica, 25 parts of divaricate saposhnikovia root, 15 parts of frankincense, 15 parts of myrrh, 40 parts of garden balsam stem, 50 parts of dried ginger, 20 parts of dog bone, 30 parts of white paeony root, 30 parts of asarum, 30 parts of szechuan lovage rhizome, 50 parts of pseudo-ginseng, 25 parts of kadsura pepper stem, 25 parts of honeysuckle stem, 35 parts of mollissima, 30 parts of figwort root, 20 parts of pangolin scales, 50 parts of zedoary, 30 parts of liquorice, 30 parts of vinegar rhizoma corydalis, 30 parts of mint, 25 parts of clove, 50 parts of medicinal cyathula;

(2) frying 1500 parts of yellow lead with slow fire until the water in the lead is dispersed completely, and cooling for later use;

(3) putting 2200 parts of vegetable oil into a pot, boiling with strong fire for 15 minutes, then decocting with slow fire for 60 minutes, slowly adding the fried yellow lead obtained in the step (2) into the vegetable oil pot while stirring, slowly adding the Chinese medicinal mixed powder obtained in the step (1) into the vegetable oil pot after the vegetable oil is slightly cold, uniformly stirring, and finally pouring the plaster on kraft paper or special plaster cloth to obtain the plaster.

Example 4

(1) Weighing the raw materials according to a formula, mixing and drying 15 parts of earthworm, 16 parts of trogopterus dung, 12 parts of radix linderae, 22 parts of radix clematidis, 20 parts of herba aristolochiae, 12 parts of rhizoma atractylodis, 12 parts of angelica sinensis, 20 parts of notopterygium root, 32 parts of safflower, 22 parts of radix angelicae, 18 parts of radix sileris, 12 parts of frankincense, 11 parts of myrrh, 32 parts of garden balsam stem, 35 parts of rhizoma zingiberis, 16 parts of dog bone, 22 parts of radix paeoniae alba, 22 parts of asarum, 22 parts of ligusticum wallichii, 35 parts of pseudo-ginseng, 21 parts of caulis piperis futokadsurae, 22 parts of honeysuckle stem, 32 parts of mollissimae, 20 parts of radix scrophulariae, 16 parts of pangolin scales, 35 parts of rhizoma zedoariae, 20 parts of liquorice, 26 parts of vinegar rhizoma corydalis, 20 parts of mint, 22 parts of clove, 35 parts of radix cyathulae and 25 parts;

(2) parching 1300 parts of Plumbum Preparatium with slow fire until water in the pill is dispersed completely, and cooling;

(3) adding 1900 parts of vegetable oil into a pot, boiling with strong fire for 12 minutes, then decocting with slow fire for 50 minutes, slowly adding the fried yellow lead obtained in the step (2) into the vegetable oil pot while stirring, slowly adding the traditional Chinese medicine mixed powder obtained in the step (1) into the vegetable oil pot after the vegetable oil is slightly cold, uniformly stirring, and finally pouring the plaster on kraft paper or special plaster cloth to obtain the plaster.

Example 5

(1) Weighing the raw materials according to a formula, mixing and drying 20 parts of earthworm, 18 parts of trogopterus dung, 13 parts of radix linderae, 28 parts of radix clematidis, 25 parts of herba aristolochiae, 18 parts of rhizoma atractylodis, 18 parts of angelica sinensis, 25 parts of notopterygium root, 38 parts of safflower, 28 parts of radix angelicae, 22 parts of divaricate saposhnikovia root, 14 parts of frankincense, 14 parts of myrrh, 38 parts of garden balsam stem, 45 parts of dried ginger, 18 parts of dog bone, 28 parts of white paeony root, 28 parts of asarum, 26 parts of ligusticum wallichii, 45 parts of pseudo-ginseng, 24 parts of kadsura pepper stem, 24 parts of honeysuckle stem, 34 parts of wooly datchmanspipe herb, 25 parts of radix scrophulariae, 18 parts of stir-baked squama manitis, 45 parts of rhizoma zedoariae, 25 parts of liquorice, 28 parts of vinegar rhizoma corydalis, 25 parts of mint, 24 parts of clove, 45 parts;

(2) parching 1400 parts of Plumbum Preparatium with slow fire until the water in the pill is dispersed completely, and cooling;

(3) putting 2100 parts of vegetable oil into a pot, boiling with strong fire for 13 minutes, then decocting with slow fire for 55 minutes, slowly adding the fried yellow lead obtained in the step (2) into the vegetable oil pot while stirring, slowly adding the traditional Chinese medicine mixed powder obtained in the step (1) into the vegetable oil pot after the vegetable oil is slightly cold, uniformly stirring, and finally pouring the plaster on kraft paper or special plaster cloth to obtain the plaster.

And (3) clinical trials:

1. the experimental population is as follows:

selecting 600 patients with cervical spondylosis, lumbar spondylosis, arthralgia, tenosynovitis, tennis elbow and old bone injury, wherein 385 patients are male, 215 patients are female and the age is 20-70 years old; the treatment group and the control group are divided into 350 cases in the treatment group and 250 cases in the control group.

2. The medication condition is as follows:

treatment groups: the plaster prepared in the invention example 1 is applied to the affected part, and the plaster is replaced once every 12 hours, and the total plaster is applied for 20 times.

Control group: applying the ostealgia plaster to the affected part, and changing the plaster once every 12 hours for 20 times.

3. And (4) conclusion:

treatment groups: the total effective rate is 93.2%, no obvious abnormality is found in routine examination of blood, urine and feces and examination of electrocardiogram, liver function and kidney function, and allergy phenomena such as redness, swelling, pruritus and the like do not appear on affected parts of patients.

Control group: the total effective rate is 80.6%, and no obvious abnormality is found in routine examination of blood, urine and stool and examination of electrocardiogram, liver function and kidney function, and allergic phenomena such as redness, swelling, pruritus and the like appear on affected parts of individual patients.

Typical cases are:

in case 1, mr. Zhao, 52 years old, 2016 suffering from lumbar disc herniation, bedridden, pain, repeated disease, taking a lot of external medicine for treating lumbar spondylosis during the period, can not completely cure, using the plaster of the invention for 24 times, can completely cure without recurrence.

In case 2, the female with money is 61 years old, the female suffers from lumbar disc herniation for 4 years, the walking is inconvenient, all housework can not be done, and the female can be cured by pasting the plaster for 30 times without relapse.

Case 3, old mr, age 43, cervical hyperplasia for 2 years, strain, long history, headache, insomnia, restlessness, numb fingers, heavy back, and labor loss. After the plaster is applied for 22 times of healing, all the heavy physical labor can be participated, and the symptoms of headache and insomnia disappear.

Case 4, qiu woman, age 52, suffered from cervical hyperplasia for 3 years, and nearly half a year, were unable to work, and no cure was found by looking for an inquiry of physicians everywhere. After the plaster is applied for 26 times, the plaster works normally.

In case 5, Wu girl, age 28, tennis lovers suffered from tennis elbow for 1 year, were unable to hold the object with the hands, and had severe influence on normal life due to the movements of lifting water buckets, twisting towels and the like, the life was recovered to normal after the plaster of the invention was applied for 20 times, and normal tennis playing was possible.

In case 6, mr. Liu, 48 years old, when the woodworker is in 10 years old, suffers from tennis elbow, can not work in nearly 1 year, and feels pain when holding chopsticks in severe cases, and doctors ask questions everywhere and can not be cured. The plaster of the invention is applied for 32 times of healing and normally works.

In case 7, Roman, 56 years old, bruised the femur of the right leg 5 years ago, the walking was dull and painful, and the disease could not be cured completely, and the disease could be cured completely without recurrence after applying the plaster of the invention for 30 times.

In case 8, the female was born before the age of 44 years, the patient suffered from the tenosynovitis of the thumb, the movement of the thumb was blocked, and the housework could not be normally done, and the plaster of the invention can be used for 20 times of healing without relapse.

The present invention is not limited to the above-described preferred embodiments, but various modifications and changes can be made by those skilled in the art without departing from the spirit and principle of the present invention.

Claims (5)

1. The plaster for activating bone and relieving pain is characterized by being prepared from the following raw materials in parts by weight: 10-25 parts of earthworm, 15-20 parts of trogopterus dung, 10-15 parts of combined spicebush root, 20-30 parts of clematis root, 15-30 parts of Japanese tussah vine, 10-20 parts of rhizoma atractylodis, 10-20 parts of angelica, 15-30 parts of notopterygium root, 30-40 parts of safflower, 20-30 parts of angelica dahurica, 15-25 parts of divaricate saposhnikovia root, 10-15 parts of frankincense, 10-15 parts of myrrh, 30-40 parts of garden balsam stem, 30-50 parts of dried ginger, 15-20 parts of dog bone, 20-30 parts of white paeony root, 20-30 parts of asarum, 20-30 parts of szechuan lovage rhizome, 30-50 parts of pseudo-ginseng, 20-25 parts of kadsura pepper stem, 20-25 parts of honeysuckle stem, 30-35 parts of wooly mollissima, 15-30 parts of figwort root, 15-20 parts of stir-baked pan, 15-30 parts of mint, 20-25 parts of clove, 30-50 parts of medicinal cyathula root, 20-35 parts of fried eucommia bark, 1200 parts of yellow lead and 1500 parts of red sage root, and 1800 parts of vegetable oil and 2200 parts of sand-broken sage root.

2. The plaster for activating bone and relieving pain as claimed in claim 1, wherein the plaster is prepared from the following raw materials in parts by weight: 15-20 parts of earthworm, 16-18 parts of trogopterus dung, 12-13 parts of combined spicebush root, 22-28 parts of clematis root, 20-25 parts of henbane stem, 12-18 parts of rhizoma atractylodis, 12-18 parts of angelica, 20-25 parts of notopterygium root, 32-38 parts of safflower, 22-28 parts of angelica dahurica, 18-22 parts of divaricate saposhnikovia root, 12-14 parts of frankincense, 11-14 parts of myrrh, 32-38 parts of garden balsam stem, 35-45 parts of dried ginger, 16-18 parts of dog bone, 22-28 parts of white peony root, 22-28 parts of asarum, 22-26 parts of szechuan lovage rhizome, 35-45 parts of pseudo-ginseng, 21-24 parts of kadsura pepper stem, 22-24 parts of honeysuckle stem, 32-34 parts of wooly mollissima, 20-25 parts of figwort root, 16-18 parts of stir-baked pangolin scales, 20-25 parts of mint, 22-24 parts of clove, 35-45 parts of medicinal cyathula root, 25-30 parts of fried eucommia bark, 1300 parts of yellow lead and 1400 parts of vegetable oil and 1900 parts of tea.

3. The plaster for activating bone and relieving pain as claimed in claim 2, wherein the plaster is prepared from the following raw materials in parts by weight: 18 parts of earthworm, 17 parts of trogopterus dung, 12.5 parts of combined spicebush root, 25 parts of clematis root, 22 parts of henbane stem, 15 parts of rhizoma atractylodis, 15 parts of angelica, 22 parts of notopterygium root, 35 parts of safflower, 25 parts of angelica dahurica, 20 parts of divaricate saposhnikovia root, 13 parts of frankincense, 12.5 parts of myrrh, 35 parts of garden balsam stem, 40 parts of dried ginger, 17 parts of dog bone, 25 parts of white paeony root, 25 parts of asarum, 24 parts of szechuan lovage rhizome, 40 parts of pseudo-ginseng, 22.5 parts of kadsura pepper stem, 23 parts of honeysuckle stem, 33 parts of wooly datchmanspipe herb, 22.5 parts of figwort root, 17 parts of pangolin scales, 40 parts of zedoary, 22.5 parts of liquorice, 27 parts of vinegar rhizoma corydalis, 22.5 parts of mint.

4. The live bone analgesic patch as claimed in any one of claims 1 to 3 wherein the vegetable oil is one of sesame oil, cottonseed oil, rapeseed oil and peanut oil.

5. A process for preparing the live bone analgesic plaster according to any one of claims 1 to 4, comprising the steps of:

(1) weighing the raw materials according to a formula, mixing and drying earthworm, trogopterus dung, combined spicebush root, clematis root, Japanese dutchmanspipe stem, rhizoma atractylodis, Chinese angelica, notopterygium root, safflower, angelica dahurica, divaricate saposhnikovia root, frankincense, myrrh, garden balsam stem, dried ginger, dog bone, white paeony root, manchurian wildginger, szechuan lovage rhizome, pseudo-ginseng, kadsura pepper stem, honeysuckle stem, berba aristolochiae mollissimae, figwort root, stir-baked pangolin scales, zedoary, liquorice, vinegar rhizoma corydalis, mint, clove, medicinal cyathula root and stir-fried eucommia bark, crushing into 1000-fold-powder with a wall;

(2) parching Plumbum Preparatium with slow fire until water and gas in the pill are dispersed completely, and cooling;

(3) putting the vegetable oil into a pot, boiling with strong fire for 10-15 minutes, then decocting with slow fire for 45-60 minutes, slowly adding the fried yellow lead obtained in the step (2) into the vegetable oil pot, stirring while adding, slowly adding the traditional Chinese medicine mixed powder obtained in the step (1) into the vegetable oil pot after the vegetable oil is slightly cold, uniformly stirring, and finally pouring the plaster on kraft paper or special plaster cloth to obtain the plaster.