CN105250933B - A kind of preparation method of the 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots and its paste - Google Patents
A kind of preparation method of the 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots and its paste Download PDFInfo
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Abstract
The present invention relates to the preparation method of a kind of 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots and its paste, bulk pharmaceutical chemicals component is as follows: Radix Aconiti, Radix Aconiti Kusnezoffii, safflower, Rhizoma Chuanxiong, corydalis tuber, olibanum (system), myrrh (system), radix achyranthis bidentatae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, pangolin (system), Radix Angelicae Sinensis, turmeric, scorpio, dragon's blood, native copper, Rhizoma Gastrodiae, dog bone, Cortex Eucommiae, semen momordicae, dandelion, black fungus, realgar, alum, Chinese prickly ash, frutus cnidii, radix aucklandiae, santal, borneol, lycopodium calvatum, honeysuckle, gypsum, mushroom, needle mushroom, catechu, asarum.The invention also discloses the preparation methods of the Traditional Chinese medicine composition paste.The 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots of the present invention, it is quick, good effect can effectively solve the problems, such as the treatment of the diseases such as cervical vertebra pain, rheumatism atrophic arthritis, scapulohumeral periarthritis, sciatica, joint motion be unfavorable, neck-shoulder pain, lumbago and leg pain, extremity numbness, blood stasis caused by chronic strain.
Description
Technical field
The present invention relates to the preparation methods of a kind of 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots and its paste, belong to Chinese medicine
Medicine technical field.
Background technique
Due to stepping up for living standard, the accelerating rhythm of life, while not focusing on taking exercises, because wind, it is cold,
The reasons such as wet, hot and caused by cervical vertebra pain, rheumatism atrophic arthritis, scapulohumeral periarthritis, sciatica, joint motion it is unfavorable,
The people of the symptoms such as neck-shoulder pain, lumbago and leg pain caused by chronic strain, extremity numbness, blood stasis is more and more.Human body machine table, channels and collaterals because
Experience caused by wind, cold, wet, heat etc. with limbs joint and DOMS, numbness, weigh, joint stuffiness, even arthrocele is burnt
Heat etc. are a kind of disease of primary symptom, are referred to as rheumatism.
Mainly alleviate by taking anodyne the pain of body for the treatment of above-mentioned illness at present, such as there are commonly
Non-steroidal anti-inflammatory drugs and central antalgica, wherein non-steroidal anti-inflammatory drugs long-time service can cause patient's upper digestive tract inflammation, gruel
Rotten, ulcer, bleeding, seriously damage gastric mucosa, are in addition also possible to lead to the generation of cardiovascular disease；And central antalgica is mostly
Some narcoticness, single-minded, smart two classes drug, the easy habituation of such drug, country strictly manages.Therefore effective and safety to control
Treating the above disease is current urgent problem to be solved.
Chinese patent literature CN 103599402A (application number 201310624592.X) discloses a kind of cream of activating microcirculation and removing stasis medicinal
Medicine is deployed by the Chinese medicine and vaseline of following weight parts and is made: 20~40 parts of radix paeoniae rubra, 20~40 parts of olibanum, myrrh 20~40
Part, 20~40 parts of pheretima, 20~40 parts of Rhizoma Chuanxiong, 20~40 parts of dragon's blood, 20~40 parts of Radix Notoginseng, 10~30 parts of monkshood, spina gleditsiae 10
~30 parts, 10~30 parts of rhizoma homalonemae, 10~30 parts of Rhizoma Gastrodiae, 10~30 parts of Rhizoma Et Radix Notopterygii, 10~30 parts of Radix Angelicae Pubescentis, 10~30 parts of cortex acanthopanacis,
5~15 parts of ramulus cinnamomi, 5~15 parts of bush, 5~15 parts of the bletilla striata, windproof 5~15 parts, 5~15 parts of yellow lead, 5~15 parts of pueraria lobata, safflower 5
~15 parts, 5~15 parts of rhizoma corydalis, 5~15 parts of borneol, 5~15 parts of dalbergia wood, 5~15 parts of cattail pollen.
The plaster of above-mentioned activating microcirculation and removing stasis medicinal, using radix paeoniae rubra, olibanum, myrrh as monarch drug in a prescription, effect focuses on promoting blood circulation and stopping pain, and for pungent
Open gradually dissipate, expelling wind and eliminating dampness, eliminating cold to stop pain, wind-damp dispelling, logical blood network, cold dispelling numbness analgesic aspect effect it is general, can not fundamentally disappear
The unfavorable all diseases caused except train of thought is obstructed.
Corydalis tuber: pungent, bitter, temperature.Return liver, the spleen channel.Promoting blood circulation, promoting the circulation of qi, analgesic.For chest side of body, epigastric pain, chest impediment and cardialgia, warp
Close dysmenorrhea, postpartum stasis, tumbling and swelling.
Radix achyranthis bidentatae: nourishing liver and kidney, strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow are ensuringd proper downward flow of the blood.For soreness of waist and knee joint, muscles and bones is powerless, menostasis { sign }
Lump in the abdomen, dizziness due to hyperactivity of liver-YANG.
Turmeric: pungent, bitter, temperature.Returns spleen, Liver Channel.Breaking blood and promoting the circulation of qi, relieving pain of dysmenorrhea.For pricking pain in the chest, chest impediment and cardialgia, dysmenorrhea
Menostasis , Disorder lump in the abdomen, rheumatism shoulder arm pain, tumbling and swelling.
Cortex Eucommiae: nourishing liver and kidney, strengthening the bones and muscles: curing mainly kidney deficiency and liver, and pain in the loins knee is soft.
Dandelion: it is bitter, dry, it trembles with fear.Return liver, stomach meridian.It is clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.For furuncle swelling toxin, cream
Carbuncle, scrofula, hot eyes, pharyngalgia, pulmonary abscess, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
Lycopodium calvatum: slight bitter, acrid in flavour and warm in nature.Liver,spleen,kidney is returned to pass through.Dispelling wind and eliminating dampness, relaxing tendons and activating collaterals.For joint pain, bend and stretch not
Benefit.
Chinese prickly ash: warm in pain, desinsection are antipruritic.For coldness and pain in the epigastrium, vomiting and diarrhea, abdominal pain due to enterositosis；Eczema itch are controlled in external application.
Frutus cnidii: eliminating dampness wind-dispelling, desinsection is antipruritic, warming kidney and enhancing body.For pruritus vulvae leukorrhagia, eczema itch, arthritis with fixed pain caused by dampness pain in the loins, kidney deficiency
Impotence, uterus cold infertile.
Radix aucklandiae: promoting the circulation of qi, analgesic, invigorating the spleen help digestion.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of 36-flavor Glutinous Chinese medicine compositions and its paste to activate blood circulation and disperse blood clots
Preparation method.
Technical solution of the present invention is as follows:
A kind of 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
14~16 parts of Radix Aconiti, 14~16 parts of Radix Aconiti Kusnezoffii, 14~16 parts of safflower, 5~7 parts of Rhizoma Chuanxiong, 5~7 parts of corydalis tuber, olibanum
13~15 parts of (system), 13~15 parts of myrrh (system), 13~15 parts of radix achyranthis bidentatae, 14~16 parts of Rhizoma Et Radix Notopterygii, 14~16 parts of Radix Angelicae Pubescentis, pangolin
5~7 parts of (system), 15~17 parts of Radix Angelicae Sinensis, 8~10 parts of turmeric, 4~6 parts of scorpio, 4~6 parts of dragon's blood, 4~6 parts of native copper, Rhizoma Gastrodiae 4
~6 parts, 14~16 parts of dog bone, 14~16 parts of Cortex Eucommiae, 8~10 parts of semen momordicae, 8~10 parts of dandelion, 3~5 parts of black fungus, realgar
9~11 parts, 11~13 parts of alum, 10~12 parts of Chinese prickly ash, 10~12 parts of frutus cnidii, 5~7 parts of radix aucklandiae, 5~7 parts of santal, borneol 14
~16 parts, 14~16 parts of lycopodium calvatum, 14~16 parts of honeysuckle, 11~13 parts of gypsum, 1~3 part of mushroom, 1~3 part of needle mushroom, youngster
11~13 parts of tea, 2~4 parts of asarum.
Preferred according to the present invention, the 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots, bulk pharmaceutical chemicals component is as follows, is
Parts by weight:
15 parts of Radix Aconiti, 15 parts of Radix Aconiti Kusnezoffii, 15 parts of safflower, 6 parts of Rhizoma Chuanxiong, 6 parts of corydalis tuber, 14 parts of olibanum (system), myrrh (system)
14 parts, 14 parts of radix achyranthis bidentatae, 15 parts of Rhizoma Et Radix Notopterygii, 15 parts of Radix Angelicae Pubescentis, 6 parts of pangolin (system), 16 parts of Radix Angelicae Sinensis, 9 parts of turmeric, 5 parts of scorpio, dragon's blood 5
Part, 5 parts of native copper, 5 parts of Rhizoma Gastrodiae, 15 parts of dog bone, 15 parts of Cortex Eucommiae, 9 parts of semen momordicae, 9 parts of dandelion, 4 parts of black fungus, realgar 10
Part, 12 parts of alum, 11 parts of Chinese prickly ash, 11 parts of frutus cnidii, 6 parts of radix aucklandiae, 6 parts of santal, 15 parts of borneol, 15 parts of lycopodium calvatum, honeysuckle 15
Part, 12 parts of gypsum, 2 parts of mushroom, 2 parts of needle mushroom, 12 parts of catechu, 3 parts of asarum.
Chinese medicine composition of the invention can be made into any dosage form of suitable external application, for example, paste, creme, patch, powder,
Finish, tincture etc..
The preparation method of the above-mentioned 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots, includes the following steps:
(1) in proportion by olibanum (system), myrrh (system), catechu, alum, gypsum, native copper, realgar, dragon's blood, borneol through powder
After broken, powder is made in sieving；
(2) in proportion by Radix Aconiti, Radix Aconiti Kusnezoffii, safflower, Rhizoma Chuanxiong, corydalis tuber, radix achyranthis bidentatae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, pangolin (system), when
Return, turmeric, scorpio, Rhizoma Gastrodiae, dog bone, Cortex Eucommiae, semen momordicae, dandelion, black fungus, Chinese prickly ash, frutus cnidii, radix aucklandiae, santal, stretch muscle
After grass, honeysuckle, mushroom, needle mushroom, asarum is cataclasm, it is placed in frying in sesame oil, oil is taken to remove slag, is filtered, 60~90min is boiled,
Tanning oil is made；
(3) it takes red lead to be added in step (2) tanning oil obtained, stirs evenly, receive cream, just cream is made in releasing fire-toxin；
(4) first cream made from step (3) is taken, after dissolving, powder made from step (1) is proportionally added into, stirs evenly, be made three
The Traditional Chinese medicine composition paste that ten Six-elements activate blood circulation and disperse blood clots.
It is preferred according to the present invention, it further include being prepared into the 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots obtained
It is the step of finished product, specific as follows:
The 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots is cut into the circular piece of 8~12g weight, is shared on cloth, i.e.,
?.
Preferred according to the present invention, the dosage of sesame oil is 1200~1400 parts by weight in the step (2).
Preferred according to the present invention, deep-fat frying time is 120~180min in the step (2).
Preferred according to the present invention, it is 400~500 parts by weight that red lead, which obtains dosage, in the step (3).
Preferred according to the present invention, specific step is as follows for releasing fire-toxin in the step (3):
Cream is soaked in water 6~8 days, first three days change water twice daily, change daily later water 1 time.
The 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots of the present invention, with Radix Aconiti, Radix Aconiti Kusnezoffii it is pungent open gradually dissipate, wind-dispelling
Winning wet, eliminating cold to stop pain is monarch.Be aided with safflower, Rhizoma Chuanxiong, olibanum (system), myrrh (system), Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, pangolin (system) wind-dispelling dissipate
It trembles with fear, win wet, easing joint movement, activating microcirculation and removing stasis medicinal, activating collaterals and eliminating stagnation, numbness relieving and pain relieving, it is altogether minister that corydalis tuber, radix achyranthis bidentatae, which reinforce above-mentioned effect,.Fang Zhong
Again with Radix Angelicae Sinensis, scorpio, dragon's blood, native copper promoting blood circulation to remove blood stasis, logical numbness active pain relieving, turmeric reinforces above-mentioned effect；Rhizoma Gastrodiae wind-damp dispelling stops
Numbness pain；Dog bone wind-damp dispelling, strengthening the bones and muscles, Cortex Eucommiae reinforce above-mentioned effect；Semen momordicae mass dissipating and swelling eliminating, dandelion reinforce above-mentioned effect；It is black
Agaric promoting blood circulation to remove blood stasis；Realgar, alum detoxifying and relieving itching, Chinese prickly ash, frutus cnidii reinforce above-mentioned effect；Santal promoting the circulation of qi eliminating cold to stop pain, radix aucklandiae
Reinforce above-mentioned effect；Borneol active pain relieving, lycopodium calvatum reinforce above-mentioned effect；Honeysuckle, gypsum take its cold and cool, both made with radix aconiti agrestis it
The big hot temperate-dryness of pungent-warm too, and holds back the function of flesh removing toxic substances；Mushroom, needle mushroom, catechu blood-nourishing qi-restoratives, too consume to prevent temperate-dryness and feel frustrated
Blood is altogether adjutant.To make medicine, priming reaches sick institute for asarum expelling wind and clearing away cold, sensible analgesic.
The effect of compatibility mode of we had both strengthened the wind-damp dispelling of the monarch and his subjects' drug, led to blood network, and cold dispelling numbness relieves pain, and prevent
The scorching mistake of full side's pungent-warm, to protect the consumption wound for holding back skin qi and blood.Full side is played altogether, and expelling wind and clearing away cold, activating microcirculation and removing stasis medicinal removes obstruction in channels to relieve pain it
Function, suitable for chill it is wet it is outer invade, blood-stasis internal-depression, train of thought is obstructed and causes limbs, joint, numbness of skin, pain, movable unfavorable all
Disease, for the good recipe for controlling numbness pain.
We are prepared into externally applied ointment dosage form, and drug is made to directly act on diseased region, " it is cut in skin, it is thorough to be managed in meat, it takes the photograph
In air-breathing, it is melted into sepage ", " and with being controlled other than its medication detoxification gas, pressing down within poison gas and disappear, energy centralizing qi, Tong Yingwei increases drop,
Manage yin-yang, five viscera settling ".So that the active principle of drug is directly entered microcirculation, immediate treatment is carried out to diseased region and is controlled, was both kept away
The effective component for having exempted from drug is damaged through the effect of gastric acid and enzyme system, in turn avoids the involvement of other organs.Pharmacodynamics is real
Test the result shows that, microcirculation disorder can be obviously improved by being applied with this product, improve micro- blood flow velocity, inhibit inflammatory reaction, improve pain
Threshold and achieve the effect that blood circulation and channel invigorating, silt releasing and analgesia.
Raw material explanation
Though the application raw material pangolin is national second-level protected animal, pangolin marketing unit is standby in national correlation department
Case, after second class protection animal certification is sold in acquirement, sales behavior is legal, therefore the raw material is used as medicine and does not violate correlation method law
Rule.
Beneficial effect
1, the 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots of the present invention, quick, good effect can effectively solve cervical vertebra
Bitterly, rheumatism atrophic arthritis, scapulohumeral periarthritis, sciatica, joint motion be unfavorable, neck, shoulder, waist and leg caused by chronic strain
Bitterly, the treatment problem of the diseases such as extremity numbness, blood stasis.
2, the 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots of the present invention, corydalis tuber can increase the work of promoting qi circulation and relieving pain with Rhizoma Chuanxiong
With；The effect of nourishing liver and kidney, strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow can be enhanced in radix achyranthis bidentatae, Cortex Eucommiae；Turmeric matches scorpio, enhancing breaking blood and promoting the circulation of qi analgesic
Effect；Dandelion can enhance clearing heat and detoxicating, the effect of dispersing swelling and dissipating binds with semen momordicae；Lycopodium calvatum can enhance dispelling wind and eliminating dampness, and relaxing muscles and tendons is living
The effect of network；Chinese prickly ash, frutus cnidii not only can detoxifying and relieving itching, also enhancing eliminating dampness wind-dispelling, warm in pain the effect of；Radix aucklandiae enhances promoting the circulation of qi
Eliminating cold to stop pain effect.
Specific embodiment
Below with reference to embodiment, technical scheme is described further, but institute's protection scope of the present invention is not limited to
This.
Bulk pharmaceutical chemicals described in embodiment are the common marketable material medicine in this field.
Embodiment 1
A kind of 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
15 parts of Radix Aconiti, 15 parts of Radix Aconiti Kusnezoffii, 15 parts of safflower, 6 parts of Rhizoma Chuanxiong, 6 parts of corydalis tuber, 14 parts of olibanum (system), myrrh (system)
14 parts, 14 parts of radix achyranthis bidentatae, 15 parts of Rhizoma Et Radix Notopterygii, 15 parts of Radix Angelicae Pubescentis, 6 parts of pangolin (system), 16 parts of Radix Angelicae Sinensis, 9 parts of turmeric, 5 parts of scorpio, dragon's blood 5
Part, 5 parts of native copper, 5 parts of Rhizoma Gastrodiae, 15 parts of dog bone, 15 parts of Cortex Eucommiae, 9 parts of semen momordicae, 9 parts of dandelion, 4 parts of black fungus, realgar 10
Part, 12 parts of alum, 11 parts of Chinese prickly ash, 11 parts of frutus cnidii, 6 parts of radix aucklandiae, 6 parts of santal, 15 parts of borneol, 15 parts of lycopodium calvatum, honeysuckle 15
Part, 12 parts of gypsum, 2 parts of mushroom, 2 parts of needle mushroom, 12 parts of catechu, 3 parts of asarum.
The preparation method of the above-mentioned 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots, includes the following steps:
(1) in proportion by olibanum (system), myrrh (system), catechu, alum, gypsum, native copper, realgar, dragon's blood, borneol through powder
After broken, powder is made in sieving；
(2) in proportion by Radix Aconiti, Radix Aconiti Kusnezoffii, safflower, Rhizoma Chuanxiong, corydalis tuber, radix achyranthis bidentatae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, pangolin (system), when
Return, turmeric, scorpio, Rhizoma Gastrodiae, dog bone, Cortex Eucommiae, semen momordicae, dandelion, black fungus, Chinese prickly ash, frutus cnidii, radix aucklandiae, santal, stretch muscle
After grass, honeysuckle, mushroom, needle mushroom, asarum are cataclasm, it is placed in frying 120min in 1200 parts by weight sesame oil, oil is taken to remove slag, filtered
It crosses, boils 90min, tanning oil is made；
(3) it takes 400 parts by weight red leads to be added in step (2) tanning oil obtained, stirs evenly, receive cream, cream is soaked in 6 in water
It, first three days change water twice daily, change daily later water 1 time, and just cream is made；
(4) first cream made from step (3) is taken, after dissolving, powder made from step (1) is proportionally added into, stirs evenly, be made three
The Traditional Chinese medicine composition paste that ten Six-elements activate blood circulation and disperse blood clots, be then cut into 12g weight circular piece, share on cloth to get 36-flavor Glutinous
Activate blood circulation and disperse blood clots plaster.
Embodiment 2
A kind of 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
14 parts of Radix Aconiti, 16 parts of Radix Aconiti Kusnezoffii, 14 parts of safflower, 7 parts of Rhizoma Chuanxiong, 5 parts of corydalis tuber, 13 parts of olibanum (system), myrrh (system)
15 parts, 15 parts of radix achyranthis bidentatae, 14 parts of Rhizoma Et Radix Notopterygii, 16 parts of Radix Angelicae Pubescentis, 5 parts of pangolin (system), 17 parts of Radix Angelicae Sinensis, 8 parts of turmeric, 4 parts of scorpio, dragon's blood 6
Part, 4 parts of native copper, 6 parts of Rhizoma Gastrodiae, 14 parts of dog bone, 16 parts of Cortex Eucommiae, 10 parts of semen momordicae, 8 parts of dandelion, 3 parts of black fungus, realgar 11
Part, 11 parts of alum, 12 parts of Chinese prickly ash, 10 parts of frutus cnidii, 7 parts of radix aucklandiae, 7 parts of santal, 14 parts of borneol, 14 parts of lycopodium calvatum, honeysuckle 16
Part, 11 parts of gypsum, 3 parts of mushroom, 1 part of needle mushroom, 13 parts of catechu, 2 parts of asarum.
The preparation method of the above-mentioned 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots, includes the following steps:
(1) in proportion by olibanum (system), myrrh (system), catechu, alum, gypsum, native copper, realgar, dragon's blood, borneol through powder
After broken, powder is made in sieving；
(2) in proportion by Radix Aconiti, Radix Aconiti Kusnezoffii, safflower, Rhizoma Chuanxiong, corydalis tuber, radix achyranthis bidentatae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, pangolin (system), when
Return, turmeric, scorpio, Rhizoma Gastrodiae, dog bone, Cortex Eucommiae, semen momordicae, dandelion, black fungus, Chinese prickly ash, frutus cnidii, radix aucklandiae, santal, stretch muscle
After grass, honeysuckle, mushroom, needle mushroom, asarum are cataclasm, it is placed in frying 180min in 1400 parts by weight sesame oil, oil is taken to remove slag, filtered
It crosses, boils 60min, tanning oil is made；
(3) it takes 500 parts by weight red leads to be added in step (2) tanning oil obtained, stirs evenly, receive cream, cream is soaked in 8 in water
It, first three days change water twice daily, change daily later water 1 time, and just cream is made；
(4) first cream made from step (3) is taken, after dissolving, powder made from step (1) is proportionally added into, stirs evenly, be made three
The Traditional Chinese medicine composition paste that ten Six-elements activate blood circulation and disperse blood clots, be then cut into 8g weight circular piece, share on cloth to get 36-flavor Glutinous work
Blood silt plaster.
Embodiment 3
A kind of 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
16 parts of Radix Aconiti, 14 parts of Radix Aconiti Kusnezoffii, 16 parts of safflower, 5 parts of Rhizoma Chuanxiong, 7 parts of corydalis tuber, 15 parts of olibanum (system), myrrh (system)
13 parts, 13 parts of radix achyranthis bidentatae, 16 parts of Rhizoma Et Radix Notopterygii, 14 parts of Radix Angelicae Pubescentis, 7 parts of pangolin (system), 15 parts of Radix Angelicae Sinensis, 10 parts of turmeric, 6 parts of scorpio, dragon's blood 4
Part, 6 parts of native copper, 4 parts of Rhizoma Gastrodiae, 16 parts of dog bone, 14 parts of Cortex Eucommiae, 8 parts of semen momordicae, 10 parts of dandelion, 5 parts of black fungus, realgar 9
Part, 13 parts of alum, 10 parts of Chinese prickly ash, 12 parts of frutus cnidii, 5 parts of radix aucklandiae, 5 parts of santal, 16 parts of borneol, 16 parts of lycopodium calvatum, honeysuckle 14
Part, 13 parts of gypsum, 1 part of mushroom, 3 parts of needle mushroom, 11 parts of catechu, 4 parts of asarum.
The preparation method of the above-mentioned 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots, includes the following steps:
(1) in proportion by olibanum (system), myrrh (system), catechu, alum, gypsum, native copper, realgar, dragon's blood, borneol through powder
After broken, powder is made in sieving；
(2) in proportion by Radix Aconiti, Radix Aconiti Kusnezoffii, safflower, Rhizoma Chuanxiong, corydalis tuber, radix achyranthis bidentatae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, pangolin (system), when
Return, turmeric, scorpio, Rhizoma Gastrodiae, dog bone, Cortex Eucommiae, semen momordicae, dandelion, black fungus, Chinese prickly ash, frutus cnidii, radix aucklandiae, santal, stretch muscle
After grass, honeysuckle, mushroom, needle mushroom, asarum are cataclasm, it is placed in frying 150min in 1300 parts by weight sesame oil, oil is taken to remove slag, filtered
It crosses, boils 70min, tanning oil is made；
(3) it takes 450 parts by weight red leads to be added in step (2) tanning oil obtained, stirs evenly, receive cream, cream is soaked in 6 in water
~8 days, first three days changed water twice daily, changed daily later water 1 time, and just cream is made；
(4) first cream made from step (3) is taken, after dissolving, powder made from step (1) is proportionally added into, stirs evenly, be made three
The Traditional Chinese medicine composition paste that ten Six-elements activate blood circulation and disperse blood clots, be then cut into 10g weight circular piece, share on cloth to get 36-flavor Glutinous
Activate blood circulation and disperse blood clots plaster.
Comparative example 1
Chinese medicine composition as described in Example 1, the difference is that, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
10 parts of the root of Chinese clematis, 20 parts of bone-grass, 15 parts of safflower, 6 parts of Rhizoma Chuanxiong, 6 parts of corydalis tuber, 14 parts of olibanum (system), myrrh (system)
14 parts, 14 parts of radix achyranthis bidentatae, 15 parts of Rhizoma Et Radix Notopterygii, 15 parts of Radix Angelicae Pubescentis, 6 parts of pangolin (system), 16 parts of Radix Angelicae Sinensis, 9 parts of turmeric, 5 parts of scorpio, dragon's blood 5
Part, 5 parts of native copper, 5 parts of Rhizoma Gastrodiae, 15 parts of dog bone, 15 parts of Cortex Eucommiae, 9 parts of semen momordicae, 9 parts of dandelion, 4 parts of black fungus, realgar 10
Part, 12 parts of alum, 11 parts of Chinese prickly ash, 11 parts of frutus cnidii, 6 parts of radix aucklandiae, 6 parts of santal, 15 parts of borneol, 15 parts of lycopodium calvatum, honeysuckle 15
Part, 12 parts of gypsum, 2 parts of mushroom, 2 parts of needle mushroom, 12 parts of catechu, 3 parts of asarum.
The preparation method is the same as that of Example 1 for paste.
Comparative example 2
Chinese medicine composition as described in Example 1, the difference is that, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
15 parts of Radix Aconiti, 15 parts of Radix Aconiti Kusnezoffii, 12 parts of peach kernel, 9 parts of rhizoma corydalis, 10 parts of Radix Curcumae, 18 parts of turmeric, lycopodium calvatum 12
Part, 18 parts of lanatechead saussurea herb with flower, 9 parts of rhizoma dioscoreae nipponicae, 16 parts of Radix Angelicae Sinensis, 5 parts of scorpio, 5 parts of dragon's blood, 5 parts of native copper, 5 parts of Rhizoma Gastrodiae, 15 parts of dog bone,
15 parts of Cortex Eucommiae, 9 parts of semen momordicae, 9 parts of dandelion, 4 parts of black fungus, 10 parts of realgar, 12 parts of alum, 11 parts of Chinese prickly ash, 11 parts of frutus cnidii,
6 parts of radix aucklandiae, 6 parts of santal, 15 parts of borneol, 15 parts of honeysuckle, 12 parts of gypsum, 2 parts of mushroom, 2 parts of needle mushroom, 12 parts of catechu, asarum 3
Part.
The preparation method is the same as that of Example 1 for paste.
Comparative example 3
Chinese medicine composition as described in Example 1, the difference is that, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
15 parts of Radix Aconiti, 15 parts of Radix Aconiti Kusnezoffii, 15 parts of safflower, 6 parts of Rhizoma Chuanxiong, 6 parts of corydalis tuber, 14 parts of olibanum (system), myrrh (system)
14 parts, 14 parts of radix achyranthis bidentatae, 15 parts of Rhizoma Et Radix Notopterygii, 15 parts of Radix Angelicae Pubescentis, 6 parts of pangolin (system), 16 parts of Radix Angelicae Sinensis, 9 parts of turmeric, 5 parts of scorpio, dragon's blood 5
Part, 5 parts of native copper, 5 parts of Rhizoma Gastrodiae, 15 parts of dog bone, 15 parts of Cortex Eucommiae, 9 parts of semen momordicae, 9 parts of dandelion, 4 parts of black fungus, realgar 10
Part, 12 parts of alum, 11 parts of Chinese prickly ash, 8 parts of frutus cnidii, 14 parts of santal, 18 parts of camphor, 12 parts of Fructus Forsythiae, 9 parts of rhizoma anemarrhenae, 5 parts of ganoderma lucidum, what
5 parts of the tuber of multiflower knotweed, 3 parts of asarum.
The preparation method is the same as that of Example 1 for paste.
Comparative example 4
Chinese medicine composition as described in Example 1, the difference is that, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
15 parts of Radix Aconiti, 15 parts of Radix Aconiti Kusnezoffii, 15 parts of safflower, 6 parts of Rhizoma Chuanxiong, 6 parts of corydalis tuber, 14 parts of olibanum (system), myrrh (system)
14 parts, 14 parts of radix achyranthis bidentatae, 15 parts of Rhizoma Et Radix Notopterygii, 15 parts of Radix Angelicae Pubescentis, 6 parts of pangolin (system), 16 parts of Radix Angelicae Sinensis, 9 parts of turmeric, 5 parts of scorpio, dragon's blood 5
Part, 5 parts of native copper, 5 parts of Rhizoma Gastrodiae, 15 parts of dog bone, 15 parts of Cortex Eucommiae, 9 parts of semen momordicae, 9 parts of dandelion, 4 parts of black fungus, realgar 10
Part, 12 parts of alum, 11 parts of Chinese prickly ash, 11 parts of frutus cnidii, 6 parts of radix aucklandiae, 6 parts of santal, 15 parts of borneol, 15 parts of lycopodium calvatum, honeysuckle 15
Part, 12 parts of gypsum, 2 parts of mushroom, 2 parts of needle mushroom, 12 parts of catechu, 1 part of the flower bud of lily magnolia.
The preparation method is the same as that of Example 1 for paste.
Comparative example 5
A kind of Chinese medicine composition to activate blood circulation and disperse blood clots, it is parts by weight that bulk pharmaceutical chemicals component is as follows:
10 parts of Radix Aconiti, 20 parts of Radix Aconiti Kusnezoffii, 10 parts of safflower, 10 parts of Rhizoma Chuanxiong, 10 parts of corydalis tuber, 10 parts of olibanum (system), myrrh
20 parts of (system), 10 parts of radix achyranthis bidentatae, 20 parts of Rhizoma Et Radix Notopterygii, 10 parts of Radix Angelicae Pubescentis, 10 parts of pangolin (system), 20 parts of Radix Angelicae Sinensis, 15 parts of turmeric, scorpio 10
Part, 2 parts of dragon's blood, 2 parts of native copper, 2 parts of Rhizoma Gastrodiae, 10 parts of dog bone, 10 parts of Cortex Eucommiae, 15 parts of semen momordicae, 12 parts of dandelion, black fungus 1
Part, 3 parts of realgar, 5 parts of alum, 8 parts of Chinese prickly ash, 15 parts of frutus cnidii, 3 parts of radix aucklandiae, 10 parts of santal, 10 parts of borneol, 20 parts of lycopodium calvatum, gold
20 parts of honeysuckle flower, 5 parts of gypsum, 5 parts of mushroom, 5 parts of needle mushroom, 8 parts of catechu, 1 part of asarum.
The preparation method is the same as that of Example 1 for paste.
Test example
Select case standard
There is rheumatism attacked by the cold and evil history, have joint or muscle is miserable, numb, pain, activity are difficult, to the cold or Changes in weather
(cloudy day rains, blows) aggravation.It excludes by fracture, dislocation, tumour, deformity, endocrine and is metabolized caused arthralgia trouble
Person；The joint caused pain patients of rheumatoid arthritis, ankylosing spondylitis, rheumatic fever are turned out to be on inspection；Merging angiocarpy,
The severe primaries such as liver, kidney and hemopoietic system disease, mental patient；Pregnant woman or breast feeding women, allergic constitution or to Chinese medicine
Allergy sufferers.
Diagnostic criteria
Wind-cold-dampness arthralgia Standards of Chinese Medical Syndrome Differentiation: limb muscle, arthralgia, heavy or swelling and pain, local chilly, skin is red,
Not hot, the pain increase in intensity under coldness of touching, pain alleviated while getting warmth, the fat matter of tongue is light secretly, whitens, and stringy and tense pulse or string are slow.
Therapeutic scheme
The cold rheumatoid joint pain patient for meeting diagnostic criteria adds paste obtained in embodiment 1-3 and comparative example 1-5
Affected part is spread on after temperature softening, dressing is primary weekly, and surrounding is as a treatment course.
Safety observations
1. general physical examination project and laboratory check
Blood routine, routine urinalysis, stool routine examination, hepatic and renal function, Electrocardiography have been carried out to 100 patients before and after medication,
It is showed no abnormal change after medication, the results are shown in Table 1.
Table 1
Curative effect judging standard
Clinical efficacy:
(1) clinical cure: the symptoms such as affected joints, myalgia, swelling, sign disappearance, joint motion are freely.
(2) effective: affected joints, myalgia disappear, and function of joint returns to normal.
(3) effectively: affected joints, myalgia or swelling take a favorable turn.
(4) invalid: affected joints, muscle symptoms are without improvement person after medication 7 days.
The clinical therapeutic efficacy of embodiment 1-3 and comparative example 1-5 are as shown in table 2:
Table 2
Upper exterior syndrome is bright, and the present invention is obvious to the therapeutic effect of wind-cold-dampness arthralgia symptom, and effective percentage is to control 97.00% or more
Treat the active drug of wind-cold-dampness arthralgia symptom.And it can be seen from upper data our monarch, minister, help, keep medicine compatibility reasonable, it is common to make
With that can play remarkable effect, above-mentioned all medicines replace with other alternative medicines of similar effect, will lead to the decline of curative effect.
Meanwhile it can be seen that by the experimental result of embodiment and comparative example 5.The weight proportion of each component is also of crucial importance,
When the variation of the proportion of each component, clinical efficacy is decreased obviously.This patent monarch minister, helps, makes to be formulated and match rationally, prepares work
Skill is stablized feasible.In conclusion the present invention is for treating various wind-cold-dampness arthralgia symptom good effects, especially to waist-leg, shoulder arm pain,
The symptoms such as extremity numbness, local swelling are effect improved significant and easy to use.Therefore this medicine drug safety, performance stabilization can
It leans on.
Claims (8)
1. a kind of 36-flavor Glutinous Chinese medicine composition to activate blood circulation and disperse blood clots, which is characterized in that bulk pharmaceutical chemicals component is as follows, is parts by weight:
14~16 parts of Radix Aconiti, 14~16 parts of Radix Aconiti Kusnezoffii, 14~16 parts of safflower, 5~7 parts of Rhizoma Chuanxiong, 5~7 parts of corydalis tuber, frankincense 13
~15 parts, 13~15 parts of myrrh, 13~15 parts of radix achyranthis bidentatae, 14~16 parts of Rhizoma Et Radix Notopterygii, 14~16 parts of Radix Angelicae Pubescentis, 5~7 parts of pangolin processed,
15~17 parts of Radix Angelicae Sinensis, 8~10 parts of turmeric, 4~6 parts of scorpio, 4~6 parts of dragon's blood, 4~6 parts of native copper, 4~6 parts of Rhizoma Gastrodiae, dog bone 14
~16 parts, 14~16 parts of Cortex Eucommiae, 8~10 parts of semen momordicae, 8~10 parts of dandelion, 3~5 parts of black fungus, 9~11 parts of realgar, alum
11~13 parts, 10~12 parts of Chinese prickly ash, 10~12 parts of frutus cnidii, 5~7 parts of radix aucklandiae, 5~7 parts of santal, 14~16 parts of borneol, stretch muscle
Grass 14~16 parts, 14~16 parts of honeysuckle, 11~13 parts of gypsum, 1~3 part of mushroom, 1~3 part of needle mushroom, 11~13 parts of catechu,
2~4 parts of asarum.
2. Chinese medicine composition as described in claim 1, which is characterized in that bulk pharmaceutical chemicals component is as follows, is parts by weight:
15 parts of Radix Aconiti, 15 parts of Radix Aconiti Kusnezoffii, 15 parts of safflower, 6 parts of Rhizoma Chuanxiong, 6 parts of corydalis tuber, 14 parts of frankincense, 14 parts of myrrh, radix achyranthis bidentatae
14 parts, 15 parts of Rhizoma Et Radix Notopterygii, 15 parts of Radix Angelicae Pubescentis, 6 parts of pangolin processed, 16 parts of Radix Angelicae Sinensis, 9 parts of turmeric, 5 parts of scorpio, 5 parts of dragon's blood, native copper 5
Part, 5 parts of Rhizoma Gastrodiae, 15 parts of dog bone, 15 parts of Cortex Eucommiae, 9 parts of semen momordicae, 9 parts of dandelion, 4 parts of black fungus, 10 parts of realgar, 12 parts of alum,
11 parts of Chinese prickly ash, 11 parts of frutus cnidii, 6 parts of radix aucklandiae, 6 parts of santal, 15 parts of borneol, 15 parts of lycopodium calvatum, 15 parts of honeysuckle, 12 parts of gypsum,
2 parts of mushroom, 2 parts of needle mushroom, 12 parts of catechu, 3 parts of asarum.
3. the preparation method of the 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots described in claim 1, which is characterized in that packet
Include following steps:
(1) in proportion by frankincense, myrrh, catechu, alum, gypsum, native copper, realgar, dragon's blood, borneol after crushed, mistake
Powder is made in sieve；
(2) in proportion by Radix Aconiti, Radix Aconiti Kusnezoffii, safflower, Rhizoma Chuanxiong, corydalis tuber, radix achyranthis bidentatae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, pangolin processed, Radix Angelicae Sinensis, ginger
Huang, scorpio, Rhizoma Gastrodiae, dog bone, Cortex Eucommiae, semen momordicae, dandelion, black fungus, Chinese prickly ash, frutus cnidii, radix aucklandiae, santal, lycopodium calvatum, gold and silver
After flower, mushroom, needle mushroom, asarum are cataclasm, it is placed in frying in sesame oil, oil is taken to remove slag, is filtered, 60~90min is boiled, tanning is made
Oil；
(3) it takes red lead to be added in step (2) tanning oil obtained, stirs evenly, receive cream, just cream is made in releasing fire-toxin；
(4) first cream made from step (3) is taken, after dissolving, powder made from step (1) is proportionally added into, stirs evenly, be made 36
The Traditional Chinese medicine composition paste that taste activates blood circulation and disperses blood clots.
4. preparation method as claimed in claim 3, which is characterized in that further include 36-flavor Glutinous activating blood circulation and dispersing blood clots obtained
The step of drug composition paste is prepared into finished product, specific as follows:
By the 36-flavor Glutinous Traditional Chinese medicine composition paste to activate blood circulation and disperse blood clots be cut into 8~12g weight circular piece, share on cloth to get.
5. preparation method as claimed in claim 3, which is characterized in that in the step (2) dosage of sesame oil be 1200~
1400 parts by weight.
6. preparation method as claimed in claim 3, which is characterized in that in the step (2) deep-fat frying time be 120~
180min。
7. preparation method as claimed in claim 3, which is characterized in that it is 400~500 that red lead, which obtains dosage, in the step (3)
Parts by weight.
8. preparation method as claimed in claim 3, which is characterized in that specific step is as follows for releasing fire-toxin in the step (3):
Cream is soaked in water 6~8 days, first three days change water twice daily, change daily later water 1 time.
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|---|---|---|---|---|
| CN1389255A (en) * | 2002-07-25 | 2003-01-08 | 佑金马 | Composite Chinese medicine for treating rheumarthritis and rheumatoid arthritis |
| CN102068647A (en) * | 2011-01-19 | 2011-05-25 | 张成海 | Chinese medicinal composition for treating lumbocrural pains by ironing and warming |
| CN102188673A (en) * | 2010-03-17 | 2011-09-21 | 赵贵凤 | Plaster for promoting muscles and bones, and preparation and application thereof |
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|---|---|---|---|---|
| CN1389255A (en) * | 2002-07-25 | 2003-01-08 | 佑金马 | Composite Chinese medicine for treating rheumarthritis and rheumatoid arthritis |
| CN102188673A (en) * | 2010-03-17 | 2011-09-21 | 赵贵凤 | Plaster for promoting muscles and bones, and preparation and application thereof |
| CN102068647A (en) * | 2011-01-19 | 2011-05-25 | 张成海 | Chinese medicinal composition for treating lumbocrural pains by ironing and warming |
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| 活血止痛散外敷治疗踝关节扭伤60例;卢晓峰;《中医研究》;20100731;第23卷(第7期);49-50 |
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