CN105288298A - Traditional Chinese medicine preparation for treating cerebral aneurysm sequelae and preparation method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for treating cerebral aneurysm sequelae and preparation method of traditional Chinese medicine preparation Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating cerebral aneurysm sequelae. The traditional Chinese medicine preparation comprises the raw materials of astragalus, ramulus cinnamomi, poria, rhizoma arisaematis, fructus lycii, flos campsis, white chrysanthemum, rhizoma pinelliae, eupolyphaga seu steleophaga, centipede, scorpio, semen cassiae, spica prunellae, radix sophorae subprostratae, radix clematidis, radix salviae miltiorrhizae, rhizoma corydalis, diverse wormwood herb, radix rehmanniae praeparata, szechuan lovage rhizome, radix paeoniae alba, angelica sinensis, fructus oryzae germinatus, and hairyvein agrimonia herb and bud, and belongs to the field of traditional Chinese medicine invention. According to different properties of all the herbs, the raw materials are cleaned, sliced, pre-treated, and then prepared in proportion by a special method to obtain the traditional Chinese medicine preparation, which has the functions of warming meridians and smoothing vessels, nourishing yin and supplementing qi, cooling blood to remove stasis, and removing stasis to reduce pain. The traditional Chinese medicine preparation is unique in product combination and preparation method, and clinical tests show that the traditional Chinese medicine preparation is remarkable in curative effect, short in treatment period, low in price and free from adverse effects and toxic or/and side effects, and has a wide market application prospect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for cerebral aneurysm sequela, the invention still further relates to the preparation method of this Chinese medicine preparation.
Background technology
Cerebral aneurysm refers to that the localized abnormality of cerebral arteries inner chamber expands and causes a kind of warty of arterial wall to give prominence to, the basis that the many birth defects because of cerebral arteries tube wall local of intracranial aneurysm and cavity pressure increase causes cystic bulging, is the first cause of disease causing subarachnoid hemorrhage.Cerebral aneurysm sequela is that aneurysm rupture often occurs suddenly, and main manifestations subarachnoid hemorrhage can be levied without location.A few patients companion intracerebral hematoma can have infull hemiplegia, aphasia, sensation and disturbance of visual field.After stopped bleeding, patient's consciousness, sings and symptoms take a turn for the better.If there is cerebral vasospasm or hemorrhage again, then patient's consciousness worsens again, to have disappeared or stable sings and symptoms again occurs or increases the weight of, has even occurred new sign.There are light headache and meningeal irritation sign, have fixing delayed ischemic neurological deficits.To severe headache and meningeal irritation sign have slight delayed ischemic neurological deficits as oculomotor paralysis or drowsiness or confusion, stiffness of the neck in severe patient, and there is delayed ischemic neurological deficits.Stupor, moderate or severe hemiplegia, have obvious delayed ischemic neurological deficits and increase the weight of in Progressive symmetric erythrokeratodermia.
At present, cerebral aneurysm sequela there is no specific short.The most at all surgical operation treats, and operation method has directly and indirect two classes.The traffic of Direct Surgery mainly between interruption artery tumor and parent artery, keeps the unobstructed of parent artery.Still removing hematocele in brain pond in early days hemorrhage simultaneously, having certain effect to preventing cerebral vasospasm.Therefore be the most reasonably treat, should first-selection be classified as.Indirect operation refers to ligation or the feeding artery by sacculus obstructing arterial tumor, with reduce aneurysmal blood for and tumor in pressure, impel thrombosis in aneurysm and inaccessible.Its curative effect is reliable not as direct method, and have cause cerebral infarction may, the normal cerebrovascular reconstruction operations that need adopt is made up, limit the use of the intracranial aneurysm in Direct Surgery can not be made, patient can be made to produce very large misery, therapeutic process again and again, DeGrain, expense is high, causes larger pressure at heart and ailing pressure to patient.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for cerebral aneurysm sequela, it is remarkable that this Chinese medicine preparation has therapeutic effect for treatment cerebral aneurysm sequela, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
Inventor is in clinical treatment practice for many years, and according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out to be used for the treatment of the new formula of the Chinese medicine preparation of cerebral aneurysm sequela repeatedly.The present invention has that therapeutic effect is remarkable, and healing time is short, cheap, has no adverse reaction and the feature of secondary toxic action.
The effect of Chinese medicine of the present invention:
Wherein:
The Radix Astragali: be leguminous plant Radix Astagali Astragalusmembranaceus(Fisch.) Bge.var.mongholicus(Bge.) Hsiao or Radix Astragali Astragalusmembranaceus(Fisch.) dry root of Bge..Nature and flavor: sweet, temperature.Return lung, spleen channel.Effect: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Ramulus Cinnamomi: be the dry twig of canella Cortex Cinnamomi CinnamomumcassiaPresl.Spring, Xia Erji gather, and except defoliation, dry, or section is dried.Nature and flavor: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.Cure mainly diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Poria: be On Polyporaceae Poria Poriacocos(Schw.) dry sclerotia of Wolf.Nature and flavor: sweet, light are flat.GUIXIN, lung, spleen, kidney channel.Effect: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.Record in " property of medicine opinion ": appetizing, preventing or arresting vomiting is inverse, kind tranquilizing mind.Main consumptive lung disease expectorant is stopped up.
Fructus Lycii: be the dry mature fruit of plant of Solanaceae lycium barbarum LyciumbarbarumL..Nature and flavor: sweet are flat.Return liver, kidney channel.Effect: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.Record in " Treatise on Dietetic Therapy ": hard muscle is always resistance to, except wind, tonification muscles and bones, the beneficial people of energy, removes asthenia.
Flos Campsis: for bavin Wei section plant is reached the clouds Campsisgrandiflora(Thunb.) K.Schum. or America reaches the clouds Campsisradicans(L.) dried floral of Seem. and root.Return liver, pericardium channel.Effect: removing heat from blood, blood stasis dispelling, dispels the wind.For menoxenia, Jing Bi WEIJIA, puerperal swelling of the breast, rubella is rubescent, skin pruritus, acne.
The Rhizoma Pinelliae: be aroid Rhizoma Pinelliae Pinelliaternata(Thunb.) dry tuber of Breit..Nature and flavor: pungent, temperature; Poisonous.Return spleen, stomach, lung meridian.Effect: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
Eupolyphaga Seu Steleophaga: be Corydiidae insecticide eupolyphoge sinensis EupolyphagasinensisWalker or Ji eupolyphoge sinensis Steleophagaplancyi(Boleny) female worm dry body.Nature and flavor: salty, cold; Slightly poisonous.Return Liver Channel.Effect: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Scolopendra: be the dry body of Scolopendridae animal Scolopendpa Subspinipes Mutilans L. KOCH ScolopendrasubspinipesmutilansL.Koch.Nature and flavor: pungent, temperature; Poisonous.Return Liver Channel.Effect: endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.Record in " detailed outline ": control pediatric epilepsy scared tetany caused by wind pathogen, infantum tetanus locked mouth, erysipelas, tinea alba, scrofula, inguinal bubo, anal fistula, Serpentis abdominal mass, thecal whitlow, snakebite.
Scorpio: be the dry body of Buthidae animal Scorpio ButhusmartensiiKarsch.Nature and flavor: pungent are flat.Return Liver Channel.Effect: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.Record in " detailed outline ": control adult Xuan malaria, deaf, hernia, all wind skin ulcers, woman's leukorrhagia, prolapse of the uterus.
Semen Cassiae: be the dry mature seed of leguminous plant Semen Cassiae CassiaobtusifoliaL. or little Semen Cassiae CassiatoraL..Nature and flavor: sweet, bitter, salty, are slightly cold.Return liver, large intestine channel.Function cures mainly: clearing away heat to improve acuity of vision, loosening bowel to relieve constipation.For the puckery pain of conjunctival congestion, the many tear of photophobia, has a headache dizzy, poor vision, constipation.Record in " Hunan medicine will ": improving eyesight, diuresis.Control giddy, beriberi, edema, lung abscess, the thoracic obstruction.
Spica Prunellae: be the dry fruit ear of labiate Spica Prunellae PrunellavulgarisL..Nature and flavor: pungent, bitter, cold.Return liver, gallbladder meridian.Effect: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.Record in " herbal classic ": main cold and heat, scrofula, scrofula, head sore, broken disease, loose wart stagnation of QI, swelling of the feet arthralgia chiefly caused by damp pathogen.
Radix Sophorae Tonkinensis: be the dry root and rhizome of leguminous plant Sophora tonkinensis Gagnep. SophoratonkinensisGapnep..Nature and flavor: bitter, cold; Poisonous.Attach to the lung and stomach meridians.Effect: heat-clearing and toxic substances removing, detumescence sore-throat relieving.Pent up for fire-toxin, laryngopharynx swelling and pain, gingivitis.Record in " Kaibao Bencao ": all poison of drug of principal solution, pain relieving.Disappear pyogenic infections from tumour or sore, and acute jaundice fever and cough, kills small worm.
Radix Clematidis: be the dry root and rhizome of ranunculaceae plant Radix Clematidis ClematischinensisOsbeck, Clematis hexapetala (mountain knotweed) ClematishexapetalaPall. or northeast clematis (black common vetch) ClematismanshuricaRupr..Nature and flavor: pungent, salty, temperature.Return urinary bladder channel.Effect: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.For rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone is choked with sobs larynx.Record in Tang Materia Medica: waist, kidney, foot knee joint, gather, all cold diseases of enteral, be not recovered for many years, the effect of clothes.
Radix Salviae Miltiorrhizae: be the dry root and rhizome of labiate Radix Salviae Miltiorrhizae SalviamiltiorrhizaBunge..Nature and flavor: bitter, are slightly cold.GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.Record in " the southern regions of the Yunnan Province book on Chinese herbal medicine ": reinforcing the heart sedate, calming heart and tranquilizing mind.Control forgetful punching seized with terror, palpitation with fear is insomnia.
Rhizoma Corydalis: be the dry tuber of papaveraceae plant corydalis CorydalisyanhusuoW.T.Wang.Nature and flavor: pungent, bitter, temperature.Return liver, spleen channel.Effect: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Record in " Japan hanako materia medica ": except wind, control gas, warm waist knee joint, broken disease addiction, flutter damage blood stasis, fall tire, and sudden and violent lumbago.
Herba Artemisiae Anomalae: be the herb of feverfew artemisia anomalas.Nature and flavor: bitter, temperature.GUIXIN, spleen channel.Effect: removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling.Control amenorrhea lump in the abdomen, chest and abdomen swelling and pain, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, Yong Du burning swelling.Record in Tang Materia Medica: main removing blood stasis, lower swollen.
Radix Rehmanniae Preparata: be the Preparation process product of Radix Rehmanniae.Nature and flavor: sweet, tepor.Return liver, kidney channel.Function cures mainly: nourishing YIN and supplementing blood, and beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.Record in " pearl sac ": enrich blood greatly empty not enough, promoting blood circulation, physical strength profiting.
Rhizoma Chuanxiong: be samphire Rhizoma Chuanxiong LigusticumchuanxiongHort.(or LigusticumwallichiiFranch.) dry rhizome.Nature and flavor: pungent, temperature.Return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Record in " Japan hanako materia medica ": control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, strengthening bone and muscle, adjusts many arteries and veins, and broken Disorder ties stagnated blood, supports fresh blood, puts on flesh, serious epistaxis, spits blood and hematuria, hemorrhoid complicated by anal fistula, brain carbuncle carbuncle on the back, and scrofula wart is gone to live in the household of one's in-laws on getting married, skin ulcer scabies, and evacuation of pus repercussive blood.
The Radix Paeoniae Alba: be the dry root of ranunculaceae plant Radix Paeoniae PaeonialactifloraPall..Nature and flavor: bitter, sour, are slightly cold.Return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.Record in " herbal classic ": main pathogen stomachache, except arthralgia due to stagnation of blood, broken hard long-pending, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
Radix Angelicae Sinensis: be umbelliferae angelica Angelicasinensis(Oliv.) dry root of Diels.Nature and flavor: sweet, acrid, warm.Return liver, the heart, spleen channel.Effect: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.Record in " Japan hanako materia medica ": control a wind cutting, all blood, mend all labor, broken stagnant blood, supports fresh blood and main Disorder addiction.
Fructus Setariae Germinatus: be grass foxtail millet Setariaitalica(L.) mature fruit of Beauv. is through germinateing drying and obtaining.Nature and flavor: sweet, temperature.Return spleen, stomach warp.Effect: help digestion and in, spleen benefiting and stimulating the appetite.Do not disappear for food stagnation, abdominal distention halitosis, weakness of the spleen and stomach, not hungry lack of appetite.Fructus Setariae Germinatus (parched) relatively helps digestion, for not hungry lack of appetite.It is stagnant that Fructus Setariae Germinatus (parched to brown) is apt to eliminate indigestion, do not disappear for stagnant.Record in " Chinese crude drug handbook ": control insufficiency of the spleen, the heart is had a stomachache, and distension, pyretic toxicity dysentery, excessive thirst, becomes thin.
Herba Agrimoniae: be the dry aerial parts of rosaceous plant Radix Agrimoniae AgrimoniapilosaLedeb..Nature and flavor: bitter, puckery are flat.GUIXIN, Liver Channel.Effect: astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.For hemoptysis, spit blood, metrostaxis, malaria, dysentery, de-power impairment caused by overstrain, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia." BAICAO mirror ": the therapeutic method to keep the adverse QI flowing downwards is invigorated blood circulation, reason all kinds of diseases and ailments, loose feeling of fullness; Fall and flutter haematemesis, metrorrhagia, dysentery, discharging fresh blood stool.
Rhizoma Arisaematis: be aroid Rhizoma Arisaematis Arisaemaerubescens(Wall.) dry tuber of Schott., Arisaema heterophyllum B1. ArisaemaheterophyllumBlume or arisaema amurense Maxim ArisaemaamurenseMaxim..Nature and flavor: bitter, pungent, temperature; Poisonous.Return lung, liver, spleen channel.Effect: drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Life uses external treatment carbuncle, snake bite and insect sting.Record in " herbal classic ": main pained, cold and heat, stagnation of QI, gathers, fullness in the epigastrium especially referring to the abcess of the abdomen in ancient times, muscle and tendon injury, flaccidity, arrests slow, dredging water passages.
Flos Chrysanthemi: be the dry capitulum of feverfew chrysanthemum ChrysanthemummorifoliumRamat..Nature and flavor: sweet, bitter, are slightly cold.Return lung, Liver Channel.Function cures mainly: loose wind heat clearing away, suppressing the hyperactive liver improving eyesight.For anemopyretic cold, have a headache dizzy, conjunctival congestion and swelling pain, eyes is dim-sighted.Record in " herbal classic ": main all dizziness due to wind, to swell and ache, order for de-, lacrimation, the dead flesh of skin, aversion to wind arthralgia chiefly caused by damp pathogen, sharp vim and vigour.
Side's solution of the present invention is: Radix Astragali invigorating QI to consolidate the body surface resistance, expelling pus and promoting granulation, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, Poria promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming, Fructus Lycii nourishing the liver and kidney, replenishing vital essence to improve eyesight, Radix Rehmanniae Preparata nourishing YIN and supplementing blood, beneficial essence fill out marrow, the pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver, nourishing blood for regulating menstruation, and above Six-element medicine is as monarch drug in side, all return kidney channel, there is the effect of warming the meridian and promoting blood circulation, YIN nourishing and QI supplementing.Chinese medicine is thought, the many evil poison of formation of cerebral aneurysm are outer invades, and interior volt blood system, causes channels impaired and give birth to.And cerebral aneurysm sequela is because of ruptured cerebral aneurysm, causes body deficient qi and blood and cause this disease symptoms.So warming the meridian and promoting blood circulation, YIN nourishing and QI supplementing are the bases for the treatment of cerebral aneurysm sequela, above Six-element medicine is monarch drug, first fundamentally warming the meridian and promoting blood circulation, YIN nourishing and QI supplementing, makes disease obtain basic control.Rhizoma Arisaematis is expellingged wind and relieving convulsion, mass dissipating and swelling eliminating, Flos Campsis cooling blood and removing stasis, Rhizoma Pinelliae drying dampness to eliminate phlegm, dissolving lump and resolving mass, Eupolyphaga Seu Steleophaga blood stasis amenorrhea, lump in the abdomen mass in the abdomen, Scolopendra merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain, Scorpio endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, Spica Prunellae relieves inflammation or internal heat improving eyesight, mass dissipating and swelling eliminating, , Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, Rhizoma Corydalis is invigorated blood circulation promoting the circulation of QI, Herba Artemisiae Anomalae removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling, Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, Herba Agrimoniae astringing to arrest bleeding, ministerial drug in the above 13 taste medicine sides of being, auxiliary monarch drug warming the meridian and promoting blood circulation on the one hand, effect of YIN nourishing and QI supplementing, there is as ministerial drug effect of cooling blood and removing stasis, removing obstruction for relieving pain on the other hand, can effectively prevent cerebral aneurysm from again recurring and causing secondary injury.Flos Chrysanthemi falls apart wind heat clearing away, suppressing the hyperactive liver improving eyesight, Semen Cassiae clearing away heat to improve acuity of vision, loosening bowel to relieve constipation, Radix Sophorae Tonkinensis heat-clearing and toxic substances removing, detumescence sore-throat relieving, Radix Clematidis expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, Fructus Setariae Germinatus help digestion and in, spleen benefiting and stimulating the appetite, above five kinds of Chinese medicine, as adjuvant drug, causes the inducement of cerebral aneurysm sequela from pathology treatment, the warming the meridian and promoting blood circulation of the monarch and his subjects two medicine, effect of YIN nourishing and QI supplementing can be promoted as adjuvant drug, the effect of body cooling blood and removing stasis, removing obstruction for relieving pain can be promoted by using corrigent the monarch and his subjects two medicine again.Simultaneously as the effect with heat-clearing and toxic substances removing, dehumidifying stomach function regulating.The all medicines of this side share, and the monarch and his subjects pull together, and minister assistant is auxiliary altogether, has effect of warming the meridian and promoting blood circulation, YIN nourishing and QI supplementing, cooling blood and removing stasis, removing obstruction for relieving pain, can effectively treat cerebral aneurysm sequela.
Another important feature of the present invention is that this Chinese medicine preparation contains abundant nutritional labeling, be rich in aminoacid and have more than 17 kinds, wherein essential amino acid has threonine, valine, methionine, isoleucine, leucine, lysine and phenylalanine, trace element containing needed by human has ferrum, chromium, copper, boron, manganese, strontium and zinc, several human body macroelement of another calcic, potassium, magnesium, phosphorus.Above nutritional labeling is all needed by human material, effectively can strengthen body immunity.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Radix Astragali 48-52g, Ramulus Cinnamomi 13-17g, Poria 18-22g, Rhizoma Arisaematis 10-14g, Fructus Lycii 16-20g, Flos Campsis 10-14g, Flos Chrysanthemi 8-12g, Rhizoma Pinelliae 8-12g, Eupolyphaga Seu Steleophaga 10-14g, Scolopendra 8-12g, Scorpio 8-12g, Semen Cassiae 22-26g, Spica Prunellae 16-20g, Radix Sophorae Tonkinensis 13-17g, Radix Clematidis 16-20g, Radix Salviae Miltiorrhizae 18-22g, Rhizoma Corydalis 16-20g, Herba Artemisiae Anomalae 18-22g, Radix Rehmanniae Preparata 16-20g, Rhizoma Chuanxiong 13-17g, Radix Paeoniae Alba 13-17g, Radix Angelicae Sinensis 16-20g, Fructus Setariae Germinatus 13-17g, Herba Agrimoniae 28-32g.
Wherein be preferably: Radix Astragali 50g, Ramulus Cinnamomi 15g, Poria 20g, Rhizoma Arisaematis 12g, Fructus Lycii 18g, Flos Campsis 12g, Flos Chrysanthemi 10g, Rhizoma Pinelliae 12g, Eupolyphaga Seu Steleophaga 12g, Scolopendra 10g, Scorpio 10g, Semen Cassiae 24g, Spica Prunellae 18g, Radix Sophorae Tonkinensis 15g, Radix Clematidis 18g, Radix Salviae Miltiorrhizae 20g, Rhizoma Corydalis 18g, Herba Artemisiae Anomalae 20g, Radix Rehmanniae Preparata 18g, Rhizoma Chuanxiong 15g, Radix Paeoniae Alba 15g, Radix Angelicae Sinensis 18g, Fructus Setariae Germinatus 15g, Herba Agrimoniae 30g.
A kind of preparation method of the Chinese medicine preparation for cerebral aneurysm sequela is as follows:
Step one: by weight of the present invention, get Radix Rehmanniae Preparata, pulverizes, and crosses 200 mesh sieves, for subsequent use;
Step 2: by weight of the present invention, get Eupolyphaga Seu Steleophaga processed, Scolopendra, Scorpio medical material be placed in marmite, add the water of 3 times of volumes, intense fire infusion 20-30 minute, lard speech with literary allusions fiery infusion 30-40 minute, filter liquor, repeatedly infusion three times, merges three filtrates, for subsequent use;
Step 3: by weight of the present invention, gets Rhizoma Corydalis and makes vinegar Rhizoma Corydalis according to Traditional Chinese medicine frying method for making vinegar, cooling, pulverizes pulverizing, crosses 200 mesh sieves, for subsequent use;
Step 4: by weight proportion of the present invention, get the Radix Astragali, Ramulus Cinnamomi, Rhizoma Arisaematis, the Rhizoma Pinelliae, Radix Sophorae Tonkinensis, Radix Clematidis, Radix Salviae Miltiorrhizae, white Peony Root be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Poria, Flos Campsis, Flos Chrysanthemi, Spica Prunellae, Herba Artemisiae Anomalae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Agrimoniae and respectively with Semen Cassiae, Fructus Lycii, Fructus Setariae Germinatus intense fire infusion 10-20 minute that bundle ties, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use;
Step 5: combining step two, step 4 gained filtrate and with step one, three gained powder, mixing, stir evenly, medicine soup is carried out concentrate and add ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, it is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment by gained concentration of liquid medicine, by air-dry for thick paste pulverizing, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, every bag containing effective ingredient 0.1g, both the honeyed pill for the treatment of cerebral aneurysm sequela of the present invention.
Using method of the present invention: get honey pill agent, takes in one hour after meal, each one bag, every day three times.
Medicine of the present invention has the effect of warming the meridian and promoting blood circulation, YIN nourishing and QI supplementing, cooling blood and removing stasis, removing obstruction for relieving pain, and good analgesic effect, cheap, have no side effect, easy to use, the mode that this Chinese medicine preparation adopts is treated and can be reduced the injury of Western medicine to patient body, alleviate the slight illness of patient, according to clinical 60 routine patient view statistics, use medicine of the present invention the total effective rate course for the treatment of 83.3%, two the total effective rate course for the treatment of 93.4%.
Detailed description of the invention
Embodiment one: Radix Astragali 50g, Ramulus Cinnamomi 15g, Poria 20g, Rhizoma Arisaematis 12g, Fructus Lycii 18g, Flos Campsis 12g, Flos Chrysanthemi 10g, Rhizoma Pinelliae 12g, Eupolyphaga Seu Steleophaga 12g, Scolopendra 10g, Scorpio 10g, Semen Cassiae 24g, Spica Prunellae 18g, Radix Sophorae Tonkinensis 15g, Radix Clematidis 18g, Radix Salviae Miltiorrhizae 20g, Rhizoma Corydalis 18g, Herba Artemisiae Anomalae 20g, Radix Rehmanniae Preparata 18g, Rhizoma Chuanxiong 15g, Radix Paeoniae Alba 15g, Radix Angelicae Sinensis 18g, Fructus Setariae Germinatus 15g, Herba Agrimoniae 30g.
Embodiment two: Radix Astragali 51g, Ramulus Cinnamomi 14g, Poria 21g, Rhizoma Arisaematis 11g, Fructus Lycii 18g, Flos Campsis 13g, Flos Chrysanthemi 11g, Rhizoma Pinelliae 11g, Eupolyphaga Seu Steleophaga 11g, Scolopendra 10g, Scorpio 10g, Semen Cassiae 23g, Spica Prunellae 17g, Radix Sophorae Tonkinensis 15g, Radix Clematidis 19g, Radix Salviae Miltiorrhizae 21g, Rhizoma Corydalis 18g, Herba Artemisiae Anomalae 21g, Radix Rehmanniae Preparata 16g, Rhizoma Chuanxiong 14g, Radix Paeoniae Alba 16g, Radix Angelicae Sinensis 17g, Fructus Setariae Germinatus 15g, Herba Agrimoniae 31g.
Embodiment three: Radix Astragali 52g, Ramulus Cinnamomi 14g, Poria 21g, Rhizoma Arisaematis 11g, Fructus Lycii 16g, Flos Campsis 12g, Flos Chrysanthemi 11g, Rhizoma Pinelliae 11g, Eupolyphaga Seu Steleophaga 11g, Scolopendra 11g, Scorpio 11g, Semen Cassiae 24g, Spica Prunellae 16g, Radix Sophorae Tonkinensis 16g, Radix Clematidis 17g, Radix Salviae Miltiorrhizae 21g, Rhizoma Corydalis 18g, Herba Artemisiae Anomalae 21g, Radix Rehmanniae Preparata 16g, Rhizoma Chuanxiong 17g, Radix Paeoniae Alba 17g, Radix Angelicae Sinensis 17g, Fructus Setariae Germinatus 15g, Herba Agrimoniae 30g.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Accept out-patient 60 example for medical treatment, patient is divided at random observation group and each 30 examples of matched group, wherein male 30 example, women 30 example, M-F 1:1, max age 66 years old, minimal ages 38 years old, course of disease some months is not by several years etc.Every basic documents such as two groups of patient ages, sex, courses of disease are substantially identical, no significant difference (P > 0.05).
Two, diagnostic criteria
1, morbidity is anxious, the symptom of typical subarachnoid hemorrhage and sign.
2, office's source symptoms such as oculomotor paralysis can be had.
3, Cranial Computed Tomography can show hematoma, subarachnoid hemorrhage situation, and CT and magnetic resonance angiography can show aneurysm.
4, cerebral angiography can make a definite diagnosis aneurysmal position and form.
Three, Therapeutic Method:
1, observation group is according to Medications Example one of the present invention, and weighting raw materials, by the treatment of invention implementation method, is got honey pill agent, taken in one hour after meal, each one bag, every day three times.
2, matched group adopts conventional western medicine Buddhist nun flat calcium ion antagonist treatment not, within 7 days, is a course for the treatment of.
Four, efficacy assessment standard:
1, cure: headache, feel sick, the clinical symptoms such as disturbance of consciousness all disappears, and do not leave any sequela.
2, take a turn for the better: the transference cures such as disturbance of consciousness, occur once in a while headache, feel sick etc. symptom, rehabilitation after continual cure a period of time.
3, invalid: through treating more than 1 week, symptom is not all felt any better person.
Five, therapeutic outcome statistics:
Matched group result is added up
Use the Comparison of therapeutic situation of this Chinese medicine preparation two groups of patients, two courses for the treatment of
Wherein: total effective rate=cure rate+improvement rate
Can find that observation group is apparently higher than matched group by the treatment total effective rate contrasting two groups of patients, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness in treatment cerebral aneurysm sequela, effectively can improve the cure rate for the treatment of, Be very effective, cheap, have no adverse reaction and any toxic and side effects, there is wide market application foreground.
Model case and curative effect:
Case one, patient Wang, female, 42 years old, people from Qingdao City, came here and goes to a doctor on January 20th, 2010.Morbidity suddenly, has symptom and the sign of typical subarachnoid hemorrhage.Cranial Computed Tomography display hematoma, subarachnoid hemorrhage situation, CT and magnetic resonance angiography can show aneurysm, are diagnosed as cerebral aneurysm sequela.Through treatment pain relief, but do not cure.Accidentally frightened before ten days, overwork in addition, occur symptom again, here treatment then, adopts made preparation in the embodiment of the present invention one, and selected preparation method, and symptom goes down, and medication, after 7 days, is thoroughly cured, and Effect of follow-up visit by telephone does not recur half a year.
Case two, patient Lee, man, 60 years old, people from Linyi, Shandong.Come here on May 14th, 2010 to go to a doctor, the sudden onset when working in farmland, has symptom and the sign of typical subarachnoid hemorrhage, Cranial Computed Tomography display hematoma, subarachnoid hemorrhage situation, CT and magnetic resonance angiography can show aneurysm, are diagnosed as cerebral aneurysm sequela.Adopt made preparation in the embodiment of the present invention one, and selected preparation method, symptom goes down, and pain slightly alleviates, and medication is after 7 days, and pain disappears, and affected part recovers good, and continue medication 5 days, thoroughly cure, Effect of follow-up visit by telephone does not recur half a year.
Claims (4)
1. the Chinese medicine preparation for cerebral aneurysm sequela, it is characterized in that, this Chinese medicine preparation is made up of the medicine of following weight portion: Radix Astragali 48-52g, Ramulus Cinnamomi 13-17g, Poria 18-22g, Rhizoma Arisaematis 10-14g, Fructus Lycii 16-20g, Flos Campsis 10-14g, Flos Chrysanthemi 8-12g, Rhizoma Pinelliae 8-12g, Eupolyphaga Seu Steleophaga 10-14g, Scolopendra 8-12g, Scorpio 8-12g, Semen Cassiae 22-26g, Spica Prunellae 16-20g, Radix Sophorae Tonkinensis 13-17g, Radix Clematidis 16-20g, Radix Salviae Miltiorrhizae 18-22g, Rhizoma Corydalis 16-20g, Herba Artemisiae Anomalae 18-22g, Radix Rehmanniae Preparata 16-20g, Rhizoma Chuanxiong 13-17g, Radix Paeoniae Alba 13-17g, Radix Angelicae Sinensis 16-20g, Fructus Setariae Germinatus 13-17g, Herba Agrimoniae 28-32g.
2. the Chinese medicine preparation for cerebral aneurysm sequela according to claim 1, it is characterized in that, be made up of the medicine of following weight portion: Radix Astragali 50g, Ramulus Cinnamomi 15g, Poria 20g, Rhizoma Arisaematis 12g, Fructus Lycii 18g, Flos Campsis 12g, Flos Chrysanthemi 10g, Rhizoma Pinelliae 12g, Eupolyphaga Seu Steleophaga 12g, Scolopendra 10g, Scorpio 10g, Semen Cassiae 24g, Spica Prunellae 18g, Radix Sophorae Tonkinensis 15g, Radix Clematidis 18g, Radix Salviae Miltiorrhizae 20g, Rhizoma Corydalis 18g, Herba Artemisiae Anomalae 20g, Radix Rehmanniae Preparata 18g, Rhizoma Chuanxiong 15g, Radix Paeoniae Alba 15g, Radix Angelicae Sinensis 18g, Fructus Setariae Germinatus 15g, Herba Agrimoniae 30g.
3. the Chinese medicine preparation for cerebral aneurysm sequela according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is honey pill agent.
4. for a preparation method for the Chinese medicine preparation of cerebral aneurysm sequela, it is characterized in that, preparation method is as follows: step one: by weight of the present invention, get Radix Rehmanniae Preparata, pulverizes, and crosses 200 mesh sieves, for subsequent use; Step 2: by weight of the present invention, get Eupolyphaga Seu Steleophaga processed, Scolopendra, Scorpio medical material be placed in marmite, add the water of 3 times of volumes, intense fire infusion 20-30 minute, lard speech with literary allusions fiery infusion 30-40 minute, filter liquor, repeatedly infusion three times, merges three filtrates, for subsequent use; Step 3: by weight of the present invention, gets Rhizoma Corydalis and makes vinegar Rhizoma Corydalis according to Traditional Chinese medicine frying method for making vinegar, cooling, pulverizes pulverizing, crosses 200 mesh sieves, for subsequent use; Step 4: by weight proportion of the present invention, get the Radix Astragali, Ramulus Cinnamomi, Rhizoma Arisaematis, the Rhizoma Pinelliae, Radix Sophorae Tonkinensis, Radix Clematidis, Radix Salviae Miltiorrhizae, white Peony Root be placed in marmite, add the water of 8 times of volumes, intense fire infusion is after 20-30 minute, add Poria, Flos Campsis, Flos Chrysanthemi, Spica Prunellae, Herba Artemisiae Anomalae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Herba Agrimoniae and respectively with Semen Cassiae, Fructus Lycii, Fructus Setariae Germinatus intense fire infusion 10-20 minute that bundle ties, fiery infusion of larding speech with literary allusions obtains filtrate in 30 ~ 40 minutes, infusion merges gained filtrate three times repeatedly, for subsequent use; Step 5: combining step two, step 4 gained filtrate and with step one, three gained powder, mixing, stir evenly, medicine soup is carried out concentrate and add ethanol, place precipitation, filter, abandon precipitation, filtrate recycling ethanol, it is the thick paste of relative density 1.15 ~ 1.20 under 75 DEG C of environment by gained concentration of liquid medicine, by air-dry for thick paste pulverizing, add Mel, antiseptic, wetting agent etc., carry out beating, rubbing, one-tenth ball, dry, be distributed into bag, every bag containing effective ingredient 0.1g, both the honeyed pill for the treatment of cerebral aneurysm sequela of the present invention.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109223939A (en) * | 2017-07-10 | 2019-01-18 | 曾令元 | It is a kind of to treat cancer of the brain Chinese medicine composition and preparation method thereof |
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Application publication date: 20160203 |