CN102188595A - Chinese medicine composition for treating arthritis and preparation method thereof - Google Patents

Chinese medicine composition for treating arthritis and preparation method thereof Download PDF

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CN102188595A
CN102188595A CN2011101258178A CN201110125817A CN102188595A CN 102188595 A CN102188595 A CN 102188595A CN 2011101258178 A CN2011101258178 A CN 2011101258178A CN 201110125817 A CN201110125817 A CN 201110125817A CN 102188595 A CN102188595 A CN 102188595A
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rhizoma
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化果
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Abstract

The invention discloses a Chinese medicine composition for treating arthritis, which comprises the following raw materials in parts by weight: 40 to 80 parts of angelica, 20 to 45 parts of Sichuan lovage rhizome, 18 to 50 parts of safflower, 20 to 45 parts of herba schizonepetae, 20 to 45 parts of cassia twig, 45 to 80 parts of angelica dahurica, 15 to 45 parts of common clubmoss herb, 40 to 70 parts of fructus chaenomelis lagenariae, 20 to 40 parts of Chinese clematis root, 15 to 39 parts of notopterygium, 18 to 43 parts of divaricate saposhnikovia root, 20 to 40 parts of garter snake, 3 to 5 scorpions, 45 to 70 parts of paris polyphylla, 35 to 75 parts of brazilwood and 8 to 35 parts of homalomena rhizoma. The Chinese medicine compound is prepared by using natural plants and biological Chinese medicinal herbs as raw materials, and is used for treating rheumatisms such as arthritis, and the like by adopting the synergistic effect of each Chinese medicinal herbs without toxic or side effects.

Description

A kind of arthritic Chinese medicine composition and preparation method thereof that is used for the treatment of
Technical field
The present invention relates to a kind of Chinese medicine composition of treatment of arthritis, belong to the Chinese medicine technical field.
Background technology
In China, arthromyodynia patients such as arthritis account for 18% of population, and its sickness rate can reach 20%.Through investigation, the age, 90% women and 80% male suffered from arthritis in the crowd of over-65s, but in fact rheumatism like disease such as arthritis belong to blue or green, in, common complaint among the elderly and frequently-occurring disease, this disease has the relapse rate height, is difficult for the characteristics of radical cure.According to incompletely statistics, there is the arthritic more than 93% effectively to be treated approximately, controls repeatly and do not heal, sb.'s illness took a turn for the worse back even be forced to the edge of paralysis, severe patient can shorten 10 years life-spans.
Arthritis mainly is the arthritis pathological changes that causes owing to inflammation, infection, wound or other unknown causes from its pathogenesis, belongs to the disease of rheumatism subject.Suffer from the patient and mainly show as redness and swelling of joints, heat, pain and dysfunction etc.Theory of Chinese medical science thinks that primary disease is to take advantage of due to the empty invasion and attack of body because of imbalance of YIN and YANG, positive QI-insufficiency, cold wind.
At present, arthritic treatment mainly contains three kinds: one, and rapid-action, the good analgesic effect of Western medicine, but take a lot of side effect for a long time, seriously damage gastrointestinal function and hepatic and renal function etc., and can't effect a radical cure, easily recurrence; In case after the recurrence, symptom even can increase the weight of; Such as hormonotherapy, though onset is very fast, general dosing can only use 3-4 time in 1 year, and can't effect a radical cure too; Its two, use existing Chinese patent medicine, by oral, also can play certain therapeutical effect, but onset is slow, misery that can't very fast releasing sufferer; Its three, adopt local naturopathy methods such as microwave heat therapeutic, acupuncture, massage, the patient that just this method is light to disease, medical history is short has certain curative effect, but not good enough to the heavier patient's curative effect of disease, and same easily recurrence; The 4th, adopt operative therapy, have certain radical cure curative effect, but the expense costliness of one side operative treatment, and in operation process, develop complications easily, and dangerous.
In the prior art, Chinese patent literature CN101579484A discloses the Chinese medicine preparation of treatment rheumatalgia, said preparation is prepared from pill by following raw materials in weight portion medicine, wherein, crude drug comprises Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Fructus Chaenomelis, Olibanum, Myrrha, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Saposhnikoviae, scholar unit, Pericarpium Citri Reticulatae Viride, Radix Dipsaci, Herba Asari, Flos Carthami, Scorpio, Herba speranskiae tuberculatae, Herba Lycopodii, Radix Glycyrrhizae, the Cortex Eucommiae, Pericarpium Citri Reticulatae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Herba Schizonepetae, see the year, Cortex schizophragmatis integrifolii radicis, Rhizoma Drynariae, Radix Aconiti, the Wan of the Qin, Pheretima, the Rhizoma Anemarrhenae, Zaocys, Caulis Spatholobi, Squama Manis, rue greatly, Rhizoma Gastrodiae, chasing after wind sees, Rhizoma Cibotii, Radix Salviae Miltiorrhizae, parasitic, Radix Aconiti Kusnezoffii, Semen Strychni.The above-mentioned raw materials medicine is collaborative to can be used for deficiency of the liver and kindey, anemofrigid-damp arthralgia, arthralgia, numb limbs and tense tendons, soreness of waist and knee joint, is widely used in rheumatic arthritis, rheumatoid arthritis, hyperosteogeny, scapulohumeral periarthritis etc.
In above-mentioned Chinese medicine preparation, introduced 40 kinds of crude drug, but for Chinese medicine preparation, crude drug uses the certain toxic and side effects of too many appearance easily, and show that through clinical trial the treatment effective percentage of above-mentioned Chinese medicine preparation can only reach 63%.
Summary of the invention
Technical problem to be solved by this invention is to be used for the treatment of arthritic Chinese medicine preparation in the prior art mostly to adopt a lot of crude drug, toxic and side effects appears easily, and its treatment effective percentage can only reach 73%, and then provides a kind of arthritic Chinese medicine composition that is used for the treatment of.
The present invention realizes by following solution, a kind of Chinese medicine composition of treatment of arthritis is made up of following bulk drugs: Radix Angelicae Sinensis 40-80 part, Rhizoma Chuanxiong 20-45 part, Flos Carthami 18-50 part, Herba Schizonepetae 20-45 part, Ramulus Cinnamomi 20-45 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 45-80 part, Herba Lycopodii 15-45 part, Fructus Chaenomelis 40-70 part, Radix Clematidis 20-40 part, Rhizoma Et Radix Notopterygii 15-39 part, Radix Saposhnikoviae 18-43 part, Zaocys 20-40 part, Scorpio 3-5, Rhizoma Paridis 45-70 part, Lignum Sappan 35-75 part, Rhizoma Homalomenae 8-35 part.
Described Chinese medicine composition preferably is made up of following bulk drugs: Radix Angelicae Sinensis 50-70 part, Rhizoma Chuanxiong 25-40 part, Flos Carthami 20-40 part, Herba Schizonepetae 20-40 part, Ramulus Cinnamomi 25-40 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 50-70 part, Herba Lycopodii 20-40 part, Fructus Chaenomelis 45-65 part, Radix Clematidis 20-35 part, Rhizoma Et Radix Notopterygii 20-35 part, Radix Saposhnikoviae 20-40 part, Zaocys 20-35 part, 5 of Scorpios, Rhizoma Paridis 50-65 part, Lignum Sappan 40-70 part, Rhizoma Homalomenae 10-30 part.
More preferably form: 60 parts of Radix Angelicae Sinensis, 30 parts of Rhizoma Chuanxiongs, 30 parts on Flos Carthami, 30 parts of Herba Schizonepetae, 30 parts of Ramulus Cinnamomi, 60 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 30 parts of Herba Lycopodiis, 60 parts of Fructus Chaenomeliss, 30 parts of Radix Clematidis, 30 parts of Rhizoma Et Radix Notopterygiis, 30 parts of Radix Saposhnikoviaes, 30 parts of Zaocys, 5 of Scorpios, 60 parts of Rhizoma Paridis, 60 parts of Lignum Sappans, 15 parts of Rhizoma Homalomenaes by following bulk drugs.
In above-mentioned Chinese medicine composition, also comprise medicated wine 300-2000 part.
Described medicated wine is yellow wine or jowar wine.
The number of degrees of described jowar wine are greater than 52 °.
The dosage form of described Chinese medicine composition is powder, decoct, medicated wine.
The present invention also on the basis that discloses above-mentioned Chinese medicine composition, further discloses described Chinese drug-treated group
The preparation method of compound comprises the steps:
(1) medicated wine of specified weight part is put into container, in medicated wine, add the crude drug of specified weight part, stir after interpolation finishes;
(2) container with above-mentioned interpolation medicated wine and crude drug seals, and is to get final product in preservation 5-20 days in 0-25 ℃ the shady and cool lucifuge environment in temperature.
The traditional Chinese medical science think arthritis by positive QI-insufficiency, pathogen easily go into, blood is gone in prolonged illness, pathogen usually intruding into collateral in protracted disease so that phlegm and blood stasis forms.Treatment is controlled blood earlier to control wind, and blood is lived wind from going out, and being equipped with invigorating spleen and kidney, the body resistance strengthening and constitution consolidating, dispeling rheumatism is that main medicine cooperates realization.Solution of the present invention just is based on above-mentioned to pathogenetic understanding of rheumatism arthritis and Therapeutic Principle, and with reference to modern pharmacological research achievement, the natural Chinese medicine compositions of the blood-supplementing blood-nourishing that obtains, blood circulation promoting and blood stasis dispelling, treating blood disorders circulation of qi promoting, dredging the meridian, expelling wind and removing dampness, dephlogistication and promoting nuscle growth.By the theory of Chinese medical science prescription, this Chinese medicine composition has embodied whole distinguishes control key, has brought into play the effect in treating both the principal and the secondary aspects of a disease at the same time, strong joint, has also strengthened the human body resistance against diseases simultaneously, from truly having played the effect of " strengthening vital QI to eliminate pathogenic factors " treatment of arthritis.
This prescription not only is conceived to the joint to the treatment of this disease, also notes the adjusting of allomeric function, has emphasized that strengthening vital QI to eliminate pathogenic factors is only basic method of treatment.Set upright and to transfer the benefit liver,spleen,kidney; Eliminating evil suitable expelling wind and removing dampness, is let out turbid detoxifcation at blood circulation promoting and blood stasis dispelling.So in the prescription, Radix Angelicae Sinensis gets that it is sweet, hot, the using warming therapy nature and flavor, and ownership liver, the heart, spleen three warps, suffering can be dispersed in the cold-evil of table, can be used for enriching blood invigorating blood circulation; Radix Angelicae Dahuricae (Radix Heraclei Scabridi) acrid in the mouth, hardship, warm in nature, be used for expelling pathogenic wind from the body surface, removing damp and stopping pain; Lignum Sappan, property is flat, and sweet in the mouth, salty is returned through in the heart, liver, stomach and large intestine channel, can be used for blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain.The above-mentioned raw materials medicine is regarded as monarch drug, and its synergism can make the cool acid precipitation symptom of the warm fearness of the osteoarticular happiness of pathological changes be alleviated.
In addition, in the above-mentioned Chinese medicine composition, Ramulus Cinnamomi is warm in nature, and acrid in the mouth, sweet belongs to the heart, lung, urinary bladder channel, but the diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins; Flos Carthami is warm in nature, acrid in the mouth, GUIXIN, Liver Channel, but promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; Rhizoma Paridis can be used for heat-clearing and toxic substances removing, reducing swelling and alleviating pain.This three can be considered ministerial drug.
Rhizoma Chuanxiong is got its suffering, using warming therapy nature and flavor, belongs to liver, gallbladder, pericardium channel, is used for blood-activating and qi-promoting, wind-expelling pain-stopping; Herba Schizonepetae nature and flavor suffering, tepor are returned through lung, Liver Channel, and diffusing wind is used to induce sweat; Zaocys, property sweet-salty, flat is gone into lung, spleen two warps, but wind-damp dispelling, the meridian dredging; Scorpio, nature and flavor suffering, flat is returned Liver Channel, but endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Fructus Chaenomelis sour in the mouth warm in nature is gone into liver, spleen channel, suppressing the hyperactive liver and easing the stomach, and Shujin dries; Herba Lycopodii mildly bitter flavor, suffering, temperature is returned the liver,spleen,kidney warp, but expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral is used for joint aches, joint stuffiness.The above-mentioned raw materials medicine is considered as adjuvant drug.
Radix Clematidis, warm in nature, acrid in the mouth, salty is returned urinary bladder channel, is used for expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; Rhizoma Et Radix Notopterygii, warm in nature, acrid in the mouth, hardship are returned bladder, kidney channel, are used for cold expelling, dispel the wind dehumidifying, pain relieving; Radix Saposhnikoviae, warm in nature, acrid in the mouth, sweet is returned bladder, liver, spleen channel, but inducing diaphoresis to dispel wind wins and wets, relieving convulsion; Rhizoma Homalomenae, warm in nature, bitter in the mouth, suffering are returned liver, kidney channel, can be used for wind-damp dispelling, bone and muscle strengthening, stopping numbness pain.
Use above-mentioned Chinese medicine composition, can be so that to open greatly in patient's natural fibre line of meat, wind-cold damp pathogen is separated from table with sweating, thus it is unobstructed to reach QI and blood, and meridians are unimpeded, regulate internal organs, the merit of Yin Yang balancing.
The present invention has following advantage:
1. it is raw material that Chinese medicine composition of the present invention is selected natural plants, biological Chinese medicine for use, adopts the synergism of the Chinese medicine of respectively distinguishing the flavor of to come arthromyodynias such as treatment of arthritis, has no side effect.
2. Chinese medicine composition of the present invention based on invigorate blood circulation, wind-damp dispelling, pain relieving, pay attention to strengthening the body resistance simultaneously.At the wind-damp dispelling analgesic simultaneously, pay attention to treating both the principal and secondary aspects of a disease, can play enhancing internal organs function simultaneously, make the negative and positive coordinated balance, QI and blood is in harmonious proportion unimpeded, the function of strengthening vital QI to eliminate pathogenic factors.
3. Chinese medicine composition of the present invention has effect preferably by clinical observation to arthritis, and more the back is difficult for recurrence.
4. Chinese medicine composition of the present invention can be a medicated wine, during preparation, at first the medicated wine of specified weight part is put into container, adds the crude drug of specified weight part in medicated wine, stirs after interpolation finishes; The container of above-mentioned interpolation medicated wine and crude drug is sealed, and is to get final product in preservation 5-20 days in 0-25 ℃ the shady and cool lucifuge environment in temperature.For medicated wine, why the selected environment temperature is 0-25 ℃ a shady and cool lucifuge, be because show that only the medicated wine in this temperature range just can be dissolved out the active drug composition in the crude drug by wine stronger volatilization and osmosis after deliberation, obtain good curative effect.
The specific embodiment
Embodiment 1
Take by weighing 40 parts of Radix Angelicae Sinensis, 45 parts of Rhizoma Chuanxiongs, 18 parts on Flos Carthami, 20 parts of Herba Schizonepetae, 25 parts of Ramulus Cinnamomi, 45 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 15 parts of Herba Lycopodiis, 45 parts of Fructus Chaenomeliss, 20 parts of Radix Clematidis, 15 parts of Rhizoma Et Radix Notopterygiis, 18 parts of Radix Saposhnikoviaes, 40 parts of Zaocys, 3 of Scorpios, 70 parts of Rhizoma Paridis, 35 parts of Lignum Sappans, 35 parts of Rhizoma Homalomenaes, it is cleaned and drying, dried medical material is pulverized respectively, and crossed 100 purpose sieves.With the Chinese crude drug mix homogeneously after pulverizing, in the powder pharmaceutical that mixing obtains, add an amount of water, stir into a paste, make used Traditional Chinese Medicine for external application.
Embodiment 2
Take by weighing 80 parts of Radix Angelicae Sinensis, 20 parts of Rhizoma Chuanxiongs, 20 parts on Flos Carthami, 40 parts of Herba Schizonepetae, 20 parts of Ramulus Cinnamomi, 50 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 20 parts of Herba Lycopodiis, 40 parts of Fructus Chaenomeliss, 40 parts of Radix Clematidis, 35 parts of Rhizoma Et Radix Notopterygiis, 43 parts of Radix Saposhnikoviaes, 20 parts of Zaocys, 4 of Scorpios, 45 parts of Rhizoma Paridis, 40 parts of Lignum Sappans, 10 parts of Rhizoma Homalomenaes, it is cleaned and drying, dried medical material is pulverized respectively, and crossed 100 purpose sieves.With the Chinese crude drug mix homogeneously after pulverizing, in the powder pharmaceutical that mixing obtains, add an amount of water, stir into a paste, make used Traditional Chinese Medicine for external application.
Embodiment 3
Take by weighing 50 parts of Radix Angelicae Sinensis, 25 parts of Rhizoma Chuanxiongs, 50 parts on Flos Carthami, 45 parts of Herba Schizonepetae, 45 parts of Ramulus Cinnamomi, 80 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 45 parts of Herba Lycopodiis, 65 parts of Fructus Chaenomeliss, 35 parts of Radix Clematidis, 39 parts of Rhizoma Et Radix Notopterygiis, 40 parts of Radix Saposhnikoviaes, 30 parts of Zaocys, 5 of Scorpios, 50 parts of Rhizoma Paridis, 75 parts of Lignum Sappans, 35 parts of Rhizoma Homalomenaes, it is cleaned and drying, make decoct with adding an amount of water in the dried medical material, decocting.
Embodiment 4
Take by weighing 70 parts of Radix Angelicae Sinensis, 40 parts of Rhizoma Chuanxiongs, 40 parts on Flos Carthami, 30 parts of Herba Schizonepetae, 40 parts of Ramulus Cinnamomi, 70 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 40 parts of Herba Lycopodiis, 70 parts of Fructus Chaenomeliss, 39 parts of Radix Clematidis, 20 parts of Rhizoma Et Radix Notopterygiis, 20 parts of Radix Saposhnikoviaes, 35 parts of Zaocys, 5 of Scorpios, 65 parts of Rhizoma Paridis, 70 parts of Lignum Sappans, 30 parts of Rhizoma Homalomenaes, make decoct with adding an amount of water in the medical material, decocting.
Embodiment 5
Take by weighing 55 parts of Radix Angelicae Sinensis, 35 parts of Rhizoma Chuanxiongs, 35 parts on Flos Carthami, 40 parts of Herba Schizonepetae, 35 parts of Ramulus Cinnamomi, 65 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 38 parts of Herba Lycopodiis, 51 parts of Fructus Chaenomeliss, 30 parts of Radix Clematidis, 35 parts of Rhizoma Et Radix Notopterygiis, 37 parts of Radix Saposhnikoviaes, 35 parts of Zaocys, 5 of Scorpios, 60 parts of Rhizoma Paridis, 70 parts of Lignum Sappans, 19 parts of Rhizoma Homalomenaes, it is cleaned and drying for standby.
The yellow wine of 300 weight portions is put into container, in yellow wine, add above-mentioned standby crude drug, add
Add and stir after finishing; The container of above-mentioned interpolation yellow wine and crude drug is sealed, and preservation can obtain medicated wine in 5 days in 25 ℃ shady and cool lucifuge environment.
Embodiment 6
Take by weighing 60 parts of Radix Angelicae Sinensis, 30 parts of Rhizoma Chuanxiongs, 30 parts on Flos Carthami, 30 parts of Herba Schizonepetae, 30 parts of Ramulus Cinnamomi, 60 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 30 parts of Herba Lycopodiis, 60 parts of Fructus Chaenomeliss, 30 parts of Radix Clematidis, 30 parts of Rhizoma Et Radix Notopterygiis, 30 parts of Radix Saposhnikoviaes, 30 parts of Zaocys, 5 of Scorpios, 60 parts of Rhizoma Paridis, 60 parts of Lignum Sappans, 15 parts of Rhizoma Homalomenaes, it is cleaned and drying for standby.
The yellow wine of 800 weight portions is put into container, in yellow wine, add above-mentioned standby crude drug, add
Add and stir after finishing; The container of above-mentioned interpolation yellow wine and crude drug is sealed, and preservation can obtain medicated wine in 10 days in 10 ℃ shady and cool lucifuge environment.
Embodiment 7
It is standby to take by weighing 60 parts of Radix Angelicae Sinensis, 30 parts of Rhizoma Chuanxiongs, 30 parts on Flos Carthami, 30 parts of Herba Schizonepetae, 30 parts of Ramulus Cinnamomi, 60 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 30 parts of Herba Lycopodiis, 60 parts of Fructus Chaenomeliss, 30 parts of Radix Clematidis, 30 parts of Rhizoma Et Radix Notopterygiis, 30 parts of Radix Saposhnikoviaes, 30 parts of Zaocys, 5 of Scorpios, 60 parts of Rhizoma Paridis, 60 parts of Lignum Sappans, 15 parts of Rhizoma Homalomenaes.
52 ° of jowar wines of 2000 weight portions are put into container, in jowar wine, add above-mentioned standby
Crude drug stirs after interpolation finishes; The container of above-mentioned interpolation jowar wine and crude drug is sealed, and preservation can obtain medicated wine in 20 days in 0 ℃ shady and cool lucifuge environment.
What use in the present embodiment is that the number of degrees are 52 ° jowar wine, also can use the number of degrees to be higher than the jowar wine of arbitrary number of degrees of 52 ° as embodiment that can conversion, such as 68 ° of jowar wines.
Experimental example
Medication one is: place the pasty state Chinese medicine of embodiment 1-2 preparation on the non-woven fabrics and be affixed on the affected part, the external application time is no more than 3 hours and gets final product, and external application every day once.
The course of treatment: external application is for nine times a course of treatment
In order to show this Chinese medicine composition to arthritic therapeutic effect, the present invention is through the clinical observation of 30 routine systems, and writes down its medical history, the state of an illness, age and former Therapeutic Method and compare efficacy experiment.
In above-mentioned patient, show as arthroncus mostly, even distortion, what have reaches knee joint, elbow joint gross distortion, the limited situation of taking action also occurred, and with serious pain and inflammation performance, morning deadlock.In these patients, what the course of disease was long reaches 3 years, and what the course of disease was short also is 5 months.Wherein, 69% sufferer checks in rheumatoid factor and shows the positive, and erythrocyte sedimentation rate increases to some extent to some extent.
Clinical test results shows, only uses this Traditional Chinese Medicine for external application three times, and for the patient who joint deformity occurs, pain symptom just can be clearly better, and takes action limitedly obviously to alleviate, and the check erythrocyte sedimentation rate all descends, and rheumatoid factor also transferred feminine gender to after 6 days.The patient that 10% disease is lighter can reach the specially good effect of curing three times.
The criterion of clinical therapeutic efficacy is:
Clinical cure: the pain complete obiteration, swelling disappears, and is restored after the joint deformity, and RF turns out cloudy.
Produce effects: pain disappears, and only after Changes in weather or the fatigue, idol has hypodynia, and swelling disappears, and RF turns out cloudy.
Take a turn for the better: original state of an illness alleviates to some extent.
Invalid: symptom Signs no change.
Through the clinical trial statistics be clinical cure 26 examples, produce effects 3 examples, 1 example that takes a turn for the better, invalid sign example.
Medication two is: take the decoct with embodiment 3-4 preparation, take twice every day sooner or later, and Time of Administration is half an hour after the meal.
The course of treatment: 15 days is a course of treatment
In order to show this Chinese medicine composition to arthritic therapeutic effect, the present invention is through the clinical observation of 15 routine systems, and writes down its medical history, the state of an illness, age and former Therapeutic Method and compare efficacy experiment.
In above-mentioned patient, show as arthroncus mostly, even distortion, major part shows as deformity of knee-joint, the limited situation of taking action has appearred in part, and with comparatively serious pain and inflammation performance, morning deadlock.In these patients, what the course of disease was long reaches 3 years, and what the course of disease was short also is 8 months.Wherein, 50% sufferer checks in rheumatoid factor and shows the positive, and erythrocyte sedimentation rate increases to some extent to some extent.
Clinical test results shows, only uses this decoct 8 days, and for the patient who joint deformity occurs, pain symptom just can be clearly better, and takes action limitedly obviously to alleviate, and the check erythrocyte sedimentation rate all descends, and rheumatoid factor also transferred feminine gender to after 13 days.
The criterion of clinical therapeutic efficacy is:
Clinical cure: the pain complete obiteration, swelling disappears, and is restored after the joint deformity, and RF turns out cloudy.
Produce effects: pain disappears, and only after Changes in weather or the fatigue, idol has hypodynia, and swelling disappears, and RF turns out cloudy.
Take a turn for the better: original state of an illness alleviates to some extent.
Invalid: symptom Signs no change.
Through the clinical trial statistics be clinical cure 10 examples, produce effects 4 examples, 1 example that takes a turn for the better, invalid sign example.
Medication three is: take the medicated wine with embodiment 5-7 preparation, take twice every day sooner or later, and Time of Administration is half an hour after the meal.
The course of treatment: ten days is a course of treatment
In order to show this Chinese medicine composition to arthritic therapeutic effect, the present invention is through the clinical observation of 15 routine systems, and writes down its medical history, the state of an illness, age and former Therapeutic Method and compare efficacy experiment.
In above-mentioned patient, show as arthroncus mostly, even distortion, major part shows as the distortion of deformity of knee-joint, finger-joint, pain can't be stood, occurs joint numbness simultaneously and be taken action limited situation, and with comparatively serious pain and inflammation performance, morning, regular heating partly appearred in deadlock.In these patients, what the course of disease was long reaches 6 years, and what the course of disease was short also is 8 months.Wherein, 70% sufferer checks in rheumatoid factor and shows the positive, and erythrocyte sedimentation rate increases to some extent to some extent.
Clinical test results shows, only uses this medicated wine 5 days, and for the patient who joint deformity occurs, pain symptom just can be clearly better, and takes action limitedly obviously to alleviate, and the check erythrocyte sedimentation rate all descends, and rheumatoid factor also transferred feminine gender to after 9 days.
The criterion of clinical therapeutic efficacy is:
Clinical cure: the pain complete obiteration, swelling disappears, and is restored after the joint deformity, and RF turns out cloudy.
Produce effects: pain disappears, and only after Changes in weather or the fatigue, idol has hypodynia, and swelling disappears, and RF turns out cloudy.
Take a turn for the better: original state of an illness alleviates to some extent.
Invalid: symptom Signs no change.
Through the clinical trial statistics be clinical cure 12 examples, produce effects 2 examples, 1 example that takes a turn for the better, invalid sign example.
In above-mentioned clinical trial, we have done inspection and record to the hematuria routine before and after patient's medication, hepatic and renal function, electrocardiogram etc., contrast no abnormally, and as seen this Chinese medicine composition has no side effect.
Though the present invention elaborates it by the specific embodiment; but; the any form that does not exceed the claim protection domain that those skilled in the art should be understood that on this basis to be made and the variation of details all belong to invention which is intended to be protected.

Claims (8)

1. the Chinese medicine composition of a treatment of arthritis, it is characterized in that, form: Radix Angelicae Sinensis 40-80 part, Rhizoma Chuanxiong 20-45 part, Flos Carthami 18-50 part, Herba Schizonepetae 20-45 part, Ramulus Cinnamomi 20-45 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 45-80 part, Herba Lycopodii 15-45 part, Fructus Chaenomelis 40-70 part, Radix Clematidis 20-40 part, Rhizoma Et Radix Notopterygii 15-39 part, Radix Saposhnikoviae 18-43 part, Zaocys 20-40 part, Scorpio 3-5, Rhizoma Paridis 45-70 part, Lignum Sappan 35-75 part, Rhizoma Homalomenae 8-35 part by following bulk drugs.
2. Chinese medicine composition according to claim 1, it is characterized in that, form: Radix Angelicae Sinensis 50-70 part, Rhizoma Chuanxiong 25-40 part, Flos Carthami 20-40 part, Herba Schizonepetae 20-40 part, Ramulus Cinnamomi 25-40 part, Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 50-70 part, Herba Lycopodii 20-40 part, Fructus Chaenomelis 45-65 part, Radix Clematidis 20-35 part, Rhizoma Et Radix Notopterygii 20-35 part, Radix Saposhnikoviae 20-40 part, Zaocys 20-35 part, 5 of Scorpios, Rhizoma Paridis 50-65 part, Lignum Sappan 40-70 part, Rhizoma Homalomenae 10-30 part by following bulk drugs.
3. Chinese medicine composition according to claim 2, it is characterized in that, form: 60 parts of Radix Angelicae Sinensis, 30 parts of Rhizoma Chuanxiongs, 30 parts on Flos Carthami, 30 parts of Herba Schizonepetae, 30 parts of Ramulus Cinnamomi, 60 parts of Radix Angelicae Dahuricae (Radix Heraclei Scabridi), 30 parts of Herba Lycopodiis, 60 parts of Fructus Chaenomeliss, 30 parts of Radix Clematidis, 30 parts of Rhizoma Et Radix Notopterygiis, 30 parts of Radix Saposhnikoviaes, 30 parts of Zaocys, 5 of Scorpios, 60 parts of Rhizoma Paridis, 60 parts of Lignum Sappans, 15 parts of Rhizoma Homalomenaes by following bulk drugs.
4. Chinese medicine composition according to claim 1 and 2 is characterized in that, also comprises medicated wine 300-2000 part.
5. Chinese medicine composition according to claim 4 is characterized in that, described medicated wine is yellow wine or jowar wine.
6. Chinese medicine composition according to claim 5 is characterized in that the number of degrees of described jowar wine are greater than 52 °.
7. according to the arbitrary described Chinese medicine composition of claim 1-6, it is characterized in that the dosage form of described Chinese medicine composition is powder, decoct, medicated wine.
8. the preparation method of the described Chinese medicine composition of claim 4 comprises the steps:
(1) medicated wine of specified weight part is put into container, in medicated wine, add the crude drug of specified weight part, stir after interpolation finishes;
(2) container with above-mentioned interpolation medicated wine and crude drug seals, and is to get final product in preservation 5-20 days in 0-25 ℃ the shady and cool lucifuge environment in temperature.
CN2011101258178A 2011-05-16 2011-05-16 Chinese medicine composition for treating arthritis and preparation method thereof Pending CN102188595A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103385944A (en) * 2013-07-31 2013-11-13 钱家美 Formula for osteoproliferation and application method thereof
CN103919949A (en) * 2014-04-28 2014-07-16 化果 Traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis
CN105748842A (en) * 2016-04-06 2016-07-13 华北理工大学 Traditional Chinese medicine composition and application thereof in treatment of arthritis
CN106074750A (en) * 2016-08-15 2016-11-09 王苏敏 Chinese medicine rheumatism is clear and preparation method thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103385944A (en) * 2013-07-31 2013-11-13 钱家美 Formula for osteoproliferation and application method thereof
CN103919949A (en) * 2014-04-28 2014-07-16 化果 Traditional Chinese medicine composition for treating rheumatism and rheumatoid arthritis
CN105748842A (en) * 2016-04-06 2016-07-13 华北理工大学 Traditional Chinese medicine composition and application thereof in treatment of arthritis
CN106074750A (en) * 2016-08-15 2016-11-09 王苏敏 Chinese medicine rheumatism is clear and preparation method thereof

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Application publication date: 20110921