CN104524150A - Traditional Chinese medicine for treating amygdalitis - Google Patents

Traditional Chinese medicine for treating amygdalitis Download PDF

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Publication number
CN104524150A
CN104524150A CN201510030843.0A CN201510030843A CN104524150A CN 104524150 A CN104524150 A CN 104524150A CN 201510030843 A CN201510030843 A CN 201510030843A CN 104524150 A CN104524150 A CN 104524150A
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CN
China
Prior art keywords
parts
amygdalitis
chinese medicine
heat
anemarrhenae
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510030843.0A
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Chinese (zh)
Inventor
李海红
耿建芳
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Individual
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Individual
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Priority to CN201510030843.0A priority Critical patent/CN104524150A/en
Publication of CN104524150A publication Critical patent/CN104524150A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention relates to a traditional Chinese medicine for treating amygdalitis. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 8 parts of scutellaria baicalensis, 6 parts of anemarrhenae, 10 parts of wild chrysanthemum flower and 5 parts of salviae miltiorrhizae. The inventor considers that the amygdalitis attacks due to evil of toxic heat, depression evaporated in the lung and evaporated in the throat. The scutellaria baicalensis, the anemarrhenae and the wild chrysanthemum flower are applied to clear away heat and toxic materials in the prescription; meanwhile, the scutellaria baicalensis and the anemarrhenae are used for clearing away heat, drying dampness, purging intense heat and promoting the secretion of saliva or body fluid; the salviae miltiorrhizae is used for activating blood circulation, restoring menstrual flow and clearing away the heart-fire; the medicines are combined, work together to achieve the efficacies of clearing away heat and toxic materials, promoting the secretion of saliva or body fluid and moistening dryness, and is effectively used for treating amygdalitis. A clinical experiment proves that the amygdalitis can be effectively treated.

Description

One is used for the treatment of tonsillitic Chinese medicine
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to one and be used for the treatment of tonsillitic Chinese medicine.
Background technology
For the Lymph nodes of root of the tongue portion lymphoid tissue agglomerate.Be divided into acute lingual tonsillitis and chronic lingual tonsillitis.How chronic lingual tonsillitis or title lingual tonsillar hypertrophy, transfer to chronic by acute lingual tonsillitis recurrent exerbation.
Tonsillitis because of the Abwehrkraft des Koepers such as to suffer from cold, overtired reduce time, bring out primary disease.Chronic lingual tonsillitis transfers to chronic because of acute lingual tonsillitis recurrent exerbation, and upper respiratory tract chronic inflammatory disease, tobacco and wine are excessively, nice irritable food etc. makes lingual tonsil generation compensatory hypertrophy.
The clinical manifestation of acute tonsillitis is: upper respiratory tract infection symptoms, as dry pharynx, scorching hot and pharyngalgia etc.Pain increases the weight of gradually, and obvious mainly with one or both sides, root of the tongue portion, severe patient can be radiated in ear and cause severe pain, and patient is face of acute ill, occasionally has heating.The clinical manifestation of chronic tonsillitis is frequent pharyngeal discomfort, foreign body sensation, dry, itch, irritable cough, the symptom such as halitosis.
Medical material present Research involved in the present invention is as follows:
Radix Scutellariae [source] this product is the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.Spring, Qiu Erji excavate, and removing fibrous root and silt, hit rough bark after solarization, dry.[nature and flavor] are bitter, cold.[return through] returns lung, gallbladder, spleen, large intestine, small intestine meridian.[function cures mainly] heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.[usage and dosage] 3 ~ 9g.[storage] puts aeration-drying place, moistureproof.
The Rhizoma Anemarrhenae [source] this product is the dry rhizome of liliaceous plant Rhizoma Anemarrhenae Anemarrhena asphodeloides Bunge..Spring, Qiu Erji excavate, and removing fibrous root and silt, dry, and practise and claim " RHIZOMA ANEMARRHENAE with peet "; Or removing crust, dry.[process of preparing Chinese medicine] Rhizoma Anemarrhenae: removing impurity, cleans, runs through, cut sheet, and dry, unhairing is considered to be worth doing.[nature and flavor] are bitter, sweet, cold.[return through] returns lung, stomach, kidney channel.[function cures mainly] clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.[usage and dosage] 6 ~ 12g.[attention] is insufficiency of the spleen, and loose stool person is unsuitable.[storage] puts aeration-drying place, moistureproof.
Flos Chrysanthemi Indici [source] this product is the dry capitulum of feverfew Herba Dendranthematis indici Chrysanthemum indicum L..Autumn, to pluck when spending in season in winter two just open, dry, or dry after steaming.[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns liver, heart channel.[function cures mainly] heat-clearing and toxic substances removing.For furuncle carbuncle, conjunctival congestion and swelling pain, has a headache dizzy.[usage and dosage] 9 ~ 15g.Suitable amount used externally, decocts soup washout or cream processed is coated with outward.
Radix Salviae Miltiorrhizae [source] this product is the dry root and rhizome of labiate Radix Salviae Miltiorrhizae Salvia miltiorrhiza Bunge..Spring, Qiu Erji excavate, removing silt, dry.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.[usage and dosage] 3 ~ 15g.[attention] should not with Rhizoma et radix veratri (Radix Rhizoma Veratri) with using.[storage] puts dry place.
Summary of the invention
The present invention aims to provide one and is used for the treatment of tonsillitic Chinese medicine, by selecting suitable medical material and proportioning thereof, reaches the tonsillitic object of safe and effective healing.
In order to achieve the above object, the present invention is by the following technical solutions:
One is used for the treatment of tonsillitic Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Scutellariae 8 parts, the Rhizoma Anemarrhenae 6 parts, Flos Chrysanthemi Indici 10 parts, Radix Salviae Miltiorrhizae 5 parts.
Inventor thinks that tonsillitis is by the heresy experiencing pyretic toxicity, hot and suffocating in lung, upper steaming throat and falling ill.Use in side: Radix Scutellariae, the Rhizoma Anemarrhenae, Flos Chrysanthemi Indici be heat-clearing and toxic substances removing altogether; Radix Scutellariae, Rhizoma Anemarrhenae heat clearing and damp drying simultaneously, pathogenic fire purging is promoted the production of body fluid; Radix Salviae Miltiorrhizae promoting blood circulation to restore menstrual flow clears away heart-fire.All medicines share, and heat-clearing and toxic substances removing, promotes the production of body fluid and moisturize altogether, are effective to treat tonsillitis.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Select institute of traditional Chinese medicine to meet 119 routine out-patients of inclusive criteria year April in March, 2012 to 2013, be divided into two groups at random, observation group 60 example, man 25 example, female 35 example, 12 ~ 62 years old age; Matched group 59 example, man 26 example, female 33 example, 12 ~ 64 years old age.Two groups of sexes, age, course of disease comparing difference not statistically significant (P>0.05), have comparability.
Diagnostic criteria
Western medicine diagnose standard is with reference to the diagnostic criteria of acute tonsillitis in " all good fortune Chinese bush cherry practical paidonosologies " (the 7th edition).
Tcm diagnosis standard is with reference to the diagnostic criteria of invading type outside tonsillitis wind heat in " Chinese medical disease Standardization of diagnosis and curative effect ".
2, Therapeutic Method
The product of two groups of pungent hard stimulations of the equal fasting of treatments period.
Matched group adopts conventional therapy, oral Chai huang granule (Yangzijiang Pharmaceutical Group Co., Ltd, the accurate word Z19991005 of traditional Chinese medicines), simultaneously Physical temperature-lowering, and a body temperature >38.5 DEG C person takes acetaminophen or ibuprofen.
Observation group on this basis oral the present invention according to the obtained decoct of specific embodiment 1, every day 3 times.
Be 5 days the course for the treatment of.
3, curative effect determinate standard
1. effective: body temperature is down to normal and is stabilized in more than 2 days, Annual wool yield is told pharyngeal sense of discomfort and is disappeared, and tonsil redness obviously disappears, and spirit, diet recover normal; 2. effective: body temperature is normal, Annual wool yield is told pharyngeal sense of discomfort and is disappeared, and pharyngeal tonsillar redness alleviates, and spirit, diet improve; 3. invalid: sings and symptoms is not improved.
4, statistical procedures adopts statistic software SPSS 20.0 to carry out statistical analysis.Measurement data meets normal distribution person with ( ) represent.Enumeration data adopts x 2inspection, correction x 2inspection.Measurement data meets normal distribution and the neat person of variance adopts t to check, and those who do not meet carry out data conversion makes variance neat, and still uneven person adopts non parametric tests.Ranked data adopt wilcoxon rank test.The time data with truncation feature adopts survival analysis.
5, result
Two groups of Clinical efficacy comparisons are through rank test Z=2.04, and P=0.041, P<0.05, have statistical significance (see table 1).Effective percentage compares through x 2inspection, after treatment, observation group effective percentage is 96.67%, and matched group effective percentage is that 86.44%, two groups of effective percentage compare and have statistical significance (P=0.041, P<0.05), and observation group is better than matched group (see table 1 and table 2).
2.2 liang of groups fever time (hour) are compared because fever time is the time data with truncation feature, adopt survival analysis, two groups of average fever time observation groups are (39.71 ± 1.25) hour, matched group is (49.68 ± 1.36) hour (see table 3), two groups of fever time significant differences (P<0.01), have statistical significance.
Visible, the medicine that the present invention obtains can safe and effective treatment tonsillitis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Radix Scutellariae 8g, Rhizoma Anemarrhenae 6g, Flos Chrysanthemi Indici 10g, Radix Salviae Miltiorrhizae 5g, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of tonsillitis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: Radix Scutellariae 8g, Rhizoma Anemarrhenae 6g, Flos Chrysanthemi Indici 10g, Radix Salviae Miltiorrhizae 5g, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of tonsillitis.Oral, daily once.
Specific embodiment 3
Take: Radix Scutellariae 8g, Rhizoma Anemarrhenae 6g, Flos Chrysanthemi Indici 10g, Radix Salviae Miltiorrhizae 5g, add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of tonsillitis.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. be used for the treatment of a tonsillitic Chinese medicine, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Radix Scutellariae 8 parts, the Rhizoma Anemarrhenae 6 parts, Flos Chrysanthemi Indici 10 parts, Radix Salviae Miltiorrhizae 5 parts.
CN201510030843.0A 2015-01-22 2015-01-22 Traditional Chinese medicine for treating amygdalitis Pending CN104524150A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784456A (en) * 2015-05-15 2015-07-22 淄博夸克医药技术有限公司 Traditional Chinese medicine for treating acute tonsillitis

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1616002A (en) * 2004-09-14 2005-05-18 马耀茹 Oral administration or lozenge medicine for treating acute pharyngitis and acute tonsillitis
CN102727825A (en) * 2012-06-20 2012-10-17 葛文农 Oral medicine used for treating tonsillitis
CN103656182A (en) * 2013-12-19 2014-03-26 青岛中科菲力工程技术研发有限公司 Traditional Chinese medicine capsule for treating tonsillitis and preparation method of capsule

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1616002A (en) * 2004-09-14 2005-05-18 马耀茹 Oral administration or lozenge medicine for treating acute pharyngitis and acute tonsillitis
CN102727825A (en) * 2012-06-20 2012-10-17 葛文农 Oral medicine used for treating tonsillitis
CN103656182A (en) * 2013-12-19 2014-03-26 青岛中科菲力工程技术研发有限公司 Traditional Chinese medicine capsule for treating tonsillitis and preparation method of capsule

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104784456A (en) * 2015-05-15 2015-07-22 淄博夸克医药技术有限公司 Traditional Chinese medicine for treating acute tonsillitis

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Application publication date: 20150422

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