CN105267296A - Traditional Chinese medicine for treating erythema nodosum - Google Patents

Traditional Chinese medicine for treating erythema nodosum Download PDF

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Publication number
CN105267296A
CN105267296A CN201510858745.6A CN201510858745A CN105267296A CN 105267296 A CN105267296 A CN 105267296A CN 201510858745 A CN201510858745 A CN 201510858745A CN 105267296 A CN105267296 A CN 105267296A
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parts
ramulus
chinese medicine
erythema nodosum
eriocarpi
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CN201510858745.6A
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陈焕斌
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Abstract

The invention relates to a traditional Chinese medicine for treating erythema nodosum. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 12 parts of eriocarpous glochidion leaves, 9 parts of melothria ndica lour, 30 parts of hylocereus undatus, 12 parts of largeserrate mosla, 12 parts of schefflera pauciflora, 9 parts of lepyrodiclis holosteozides and 12 parts of ilex cornuta. Clinical experiments prove that the traditional Chinese medicine can be used for safely and effectively treating erythema nodosum.

Description

A kind of Chinese medicine being used for the treatment of erythema nodosum
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of erythema nodosum.
Background technology
Erythema nodosum is a kind of painful, nodular vasculitis syndrome of being apt to occur in young women, and pathological changes is positioned at corium deep layer and subcutaneous tissue, and its character is the skin lesion of apyetous erythema nodosum.Skin lesion performance has diameter to be the cerise erythema nodosum of 1 ~ 5cm, and how a little more than skin, obscure boundary, has edema, localized tenderness and tenderness around.Number from several to tens not etc.Many appearance suddenly, be evenly distributed, each tuberosity is many not to be merged.Tuberosity does not generally soften, also never ulceration, and also do not leave cicatrix and atrophy after disappearing, small number of patients can recurrent exerbation.
The traditional Chinese medical science: multiple abscesses due to noxious dampness, vasuclitis nodularis, the traditional Chinese medical science thinks the formation of primary disease, be because have accumulate wet, strongly fragrant heat-transformation of a specified duration, damp-heat accumulation, in blood vessels skin, causes meridians to intercept, coagulation of QI-blood and falling ill; Or because wet not changing insufficiency of the spleen accumulateing, hold concurrently sense cold-evil, and cold-damp is condensed, retardance blood vessels and causing.Sick just damp and hot heresy, pents up in blood vessels, causes coagulation of QI-blood and then see that skin plays red tuberosity, and local is scorching hot, swelling; Sick recurrent exerbation for a long time, insufficiency of the spleen accumulateing wetly is not changed, and cold-damp hinders and do not heal in passages through which vital energy circulates is then repeatedly touching.
Medical material present Research involved in the present invention is as follows:
Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) [another name] hair paint, MAOQI brother, public, the large MAOQI of MAOQI, Fructus glochidionis puberi(Herba Glochidii Puberi), calabazilla, paint uncle, poplar paint husband's aunt, cane basket fruit, the tree of itching, two sides hair, setation seven, Fortunella hindsii, eight stupefied Fructus Citri tangerinaes, octahedral Fructus Citri tangerinae, enter lobe Fructus Citri tangerinae, mountain gold melon.[source] medical material Ji Yuan: be the branch and leaf of euphorbia plant comospore Fructus glochidionis puberi(Herba Glochidii Puberi).Gather and store: summer, autumn adopt, using fresh herb or dry.[nature and flavor] bitter in the mouth; Puckery; Property is put down.[return through] stomach; Spleen; Large intestine channel.[function cures mainly] heat-clearing and toxic substances removing; Removing dampness to relieve itching.Main Resina Toxicodendri verniciflui is irritated; Paddy field dermatitis; Skin pruritus; Urticaria; Eczema; Burn; Mastitis; Acute gastroenteritis; Dysentery.[usage and dosage] takes orally: decoct soup, 5 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Horse hands over youngster's [another name] mouse to draw Fructus Benincasae, native pollen, Radix Melothriae Heterophyllae.[source] is Cucurbitaceae horse friendship youngster platymiscium horse friendship youngster, is used as medicine with root or leaf.Picking leaves in summer, autumn uproots, and cleans and dries or using fresh herb.[nature and flavor] sweet, bitter, cold.[return through] returns lung, liver, kidney three warp.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For laryngopharynx swelling and pain, conjunctivitis; Sore swollen toxin is controlled in external, tuberculous lymphadenitis, orchitis, skin eczema.[usage and dosage] takes orally: decoct soup, 5 ~ 9g.[extracts] " national Chinese herbal medicine compilation ".
Hylocereus undatus [another name] Euphorbia royleana Boiss., Ba Wanghua, Flos Hylocerei Undati, triangle hyperactivity of fire, seven-star Flos Hylocerei Undati.[source] Cactaceae Hylocereus undatus platymiscium Hylocereus undatus, is used as medicine with fleshy stem and flower.Stem can be adopted the whole year, many using fresh herbs; Flower Xia Qiucai, dries.[nature and flavor] are sweet, light, micro-cool.[return through] returns kidney, lung two warp.[function cures mainly] flower: heat clearing away, lung moistening, cough-relieving.For pulmonary tuberculosis, bronchitis, lymphoid tuberculosis; Stem: relaxing muscles and tendons and activating QI and blood in the collateral, removing toxic substances.Fracture is controlled in external, parotitis, and skin ulcer swells.[usage and dosage] takes orally: decoct soup, 25 ~ 50g.[extracts] " China's book on Chinese herbal medicine ".
Herba Moslae Grosseserratae [another name] smelly Soviet Union, bluish white Soviet Union.[source] medical material Ji Yuan: be stem, the leaf of labiate Herba Moslae Grosseserratae.Gather and store: herb of gathering the 7-8 month, drying.[nature and flavor] acrid in the mouth; Warm in nature.[return through] stomach; Large intestine channel.[function cures mainly] inducing diuresis to remove edema; Stomach function regulating antacid.Main ascites edema; Have loose bowels; Hyperchlorhydria; Abdominal pain due to worm stagnation; Swelling and pain of hemorrhoid.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Ball sequence schefflera [another name] seven Cortex Acanthopanacis Radicis, Cortex Acanthopancis.[source] medical material Ji Yuan: be root or the bark of Araliaceae ball sequence schefflera.Gather and store: the whole year all can adopt, and strips peel of stem, uproots, clean, using fresh herb or section are dried.[nature and flavor] mildly bitter flavor; Pungent; Property is put down.[return through] Liver and kidney two warp.[function cures mainly] dispelling, collateral-activating; Eliminating stasis to stop pain; Eliminating mass diuretic.Main air pain of dampness syndrome; Treating swelling and pain by traumatic injury; Fracture; Cirrhotic ascites.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Goddess's dish [source] medical material Ji Yuan: be the herb of the thin capsule grass of pinkwort.Gather and store: the 6-7 month gathers, using fresh herb or dry.[nature and flavor] are sweet; Cold in nature.[return through] returns lung meridian.[function cures mainly] heat clearing and lung benefiting; Dissipating blood stasis poison holding.Main cough due to lung-heat; Carbuncle furuncle.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Ramulus Kalopanacis seu Araliae [another name] llex cornuta, thorn root white skin, bird do not stop, tiger is careless, confused tree.[source] is the stem branch of Araliaceae Kalopanax septemlobum Huo Cortex araliae chinensis.[nature and flavor] are pungent, flat.[function cures mainly] chases after wind analgesic therapy, has deep wonderful.Control pathogenic wind toxic multiple abscess, migratory arthralgia, traumatic injury, labor is timid.Lower tire expedites the emergence of.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.The careful clothes of [attention] anemia of pregnant woman.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of erythema nodosum, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing erythema nodosum.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of erythema nodosum, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 parts, horse hand over youngster 9 parts, Hylocereus undatus 30 parts of, Herba Moslae Grosseserratae 12 parts, ball sequence schefflera 12 parts, goddess's dish 9 parts, Ramulus Kalopanacis seu Araliae 12 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and erythema nodosum patient 100 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 50 example and matched group 50 example at random, 21 ~ 67 years old treatment group age, 20 ~ 68 years old matched group age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national erythema nodosum clinical speciality:
(1.) onset is unexpected, is apt to occur in young women, more common with spring, autumn.(2.) mainly betide two shanks and stretch face, occasionally in thigh and forearm.Be just erythema, gradually develop into the cerise tuberosity of 1 ~ 5cm size, conscious pain, has tenderness, and red joint number order is more, does not merge, not ulceration.With two shin symmetry, prunus mume (sieb.) sieb.et zucc. core size occurs, painful tuberosity is cardinal symptom.(3.) slight General Symptoms is had, as low grade fever, pharyngalgia, general malaise, joint and myalgia.(4.) course of disease is from limit, and general 1 ~ February can heal, but easily recurs.
Lab testing:
(1.) routine blood test and erythrocyte sedimentation rate are generally without anemia, and leukocyte raises sometimes, and patient's erythrocyte sedimentation rate of 2/3 speeds.(2.) immunologic test is when with tuberculosis, and tuberculin test can be positive.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.One month course for the treatment of.
Matched group oral indometacin 25mg, 3 times/day, oral after the meal; Aminophylline: each oral 50mg, every day 2 ~ 3 times; Dexamethasone 1.5mg, 3 times/day.One month course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: within 3 weeks, skin lesion disappears, and no longer recurs more.
Effective: in 4 ~ 6 weeks, skin lesion disappears, and recurrence time extends than before.
Invalid: more than 6 weeks skin lesion without disappearing or increasing the weight of.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Group n Cure Effectively Invalid Total effective rate (%) Serious adverse reaction example
Treatment group 50 11 35 4 92% 0
Matched group 50 9 23 18 64% 0
Visible, the medicine that the present invention obtains can safe and effective treatment erythema nodosum, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 grams, horse hand over youngster 9 grams, Hylocereus undatus 30 grams of, Herba Moslae Grosseserratae 12 grams, ball sequence schefflera 12 grams, goddess's dish 9 grams, Ramulus Kalopanacis seu Araliae 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of erythema nodosum.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 grams, horse hand over youngster 9 grams, Hylocereus undatus 30 grams of, Herba Moslae Grosseserratae 12 grams, ball sequence schefflera 12 grams, goddess's dish 9 grams, Ramulus Kalopanacis seu Araliae 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of erythema nodosum.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 grams, horse hand over youngster 9 grams, Hylocereus undatus 30 grams of, Herba Moslae Grosseserratae 12 grams, ball sequence schefflera 12 grams, goddess's dish 9 grams, Ramulus Kalopanacis seu Araliae 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of erythema nodosum.Oral, every bu Morning Afternoon Evening is taken for three times.

Claims (4)

1. one kind is used for the treatment of the Chinese medicine of erythema nodosum, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 parts, horse hand over youngster 9 parts, Hylocereus undatus 30 parts of, Herba Moslae Grosseserratae 12 parts, ball sequence schefflera 12 parts, goddess's dish 9 parts, Ramulus Kalopanacis seu Araliae 12 parts.
2. be used for the treatment of the Chinese medicine of erythema nodosum as claimed in claim 1, it is characterized in that, its preparation method is: take: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 parts, horse hand over youngster 9 parts, Hylocereus undatus 30 parts of, Herba Moslae Grosseserratae 12 parts, ball sequence schefflera 12 parts, goddess's dish 9 parts, Ramulus Kalopanacis seu Araliae 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of erythema nodosum as claimed in claim 1, it is characterized in that, its preparation method is: take: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 parts, horse hand over youngster 9 parts, Hylocereus undatus 30 parts of, Herba Moslae Grosseserratae 12 parts, ball sequence schefflera 12 parts, goddess's dish 9 parts, Ramulus Kalopanacis seu Araliae 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of erythema nodosum as claimed in claim 1, it is characterized in that, its preparation method is: take: Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 12 parts, horse hand over youngster 9 parts, Hylocereus undatus 30 parts of, Herba Moslae Grosseserratae 12 parts, ball sequence schefflera 12 parts, goddess's dish 9 parts, Ramulus Kalopanacis seu Araliae 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
CN201510858745.6A 2015-12-01 2015-12-01 Traditional Chinese medicine for treating erythema nodosum Withdrawn CN105267296A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853731A (en) * 2016-04-20 2016-08-17 陈程辉 Medicine for treating erythema nodosum

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768169A (en) * 2013-11-15 2014-05-07 广州市云桥生物科技有限公司 Traditional Chinese medicine effective part composition for treating erythema nodosum

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768169A (en) * 2013-11-15 2014-05-07 广州市云桥生物科技有限公司 Traditional Chinese medicine effective part composition for treating erythema nodosum

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
周宝宽: ""审证求因治疗结节性红斑"", 《河北中医》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853731A (en) * 2016-04-20 2016-08-17 陈程辉 Medicine for treating erythema nodosum

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Application publication date: 20160127