CN104116857A - Traditional Chinese medicament for treating herpes zoster and preparation method thereof - Google Patents
Traditional Chinese medicament for treating herpes zoster and preparation method thereof Download PDFInfo
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- CN104116857A CN104116857A CN201410395403.0A CN201410395403A CN104116857A CN 104116857 A CN104116857 A CN 104116857A CN 201410395403 A CN201410395403 A CN 201410395403A CN 104116857 A CN104116857 A CN 104116857A
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Abstract
The invention relates to a traditional Chinese medicament for treating herpes zoster and a preparation method thereof. The traditional Chinese medicament is prepared from the following raw medicinal materials in parts by weight: 11 parts of diels stephania root, 8 parts of celastrus oblanceifolius, 23 parts of celastrus oblanceifolius, 9 parts of Chinese starjasmine stem, 36 parts of lippia, 12 parts of blumea balsamifera, 7 parts of frankincense and 2 parts of radix aconiti agrestis. Clinical experiments prove that the traditional Chinese medicament can be used for safely and effectively treating herpes zoster.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine that is used for the treatment of herpes zoster.
Background technology
Herpes zoster is to be caused by varicella zoster virus, and this virus is generally hidden in spinal cord dorsal root ganglia.But Abwehrkraft des Koepers is low or fatigue, infection, cat fever, anger is got angry etc., and virus can regrow breeding, and moves to skin along nerve fiber, makes nerve and the skin of being invaded produce fierce inflammation.The feature that erythra generally has one-sided property and distributes by nerve segment, is made up of the herpes of collection bunch property, and with pain; Age is larger, and neuralgia is heavier.This sick modern medicine is called herpes zoster, and the traditional Chinese medical science is called Fel Serpentis skin ulcer, skirt-roof dragon etc.From Chinese medical discrimination, the formation of primary disease is how not smooth by feelings will, depression of liver-QI, for a long time and fire-transformation; Or eating and drinking without temperance, dysfunction of the spleen in transportation, the strongly fragrant and heat-transformation of endogenous damp formation, retention of damp-heat in the interior, multiple evil because of diseases caused by exogenous pathogenic factor poison, so that damp and hot fire-toxin accumulates long-pending skin and gives birth to.Elderly and infirm, often because of blood-deficiency leading to hyperactivity of the liver, damp and hot malicious Sheng, coagulation of QI-blood so that sharp ache.Chinese traditional treatment is mainly searched the aspects such as poison, removing obstruction in the collateral to relieve pain, blood circulation promoting and blood stasis dispelling, dredge the meridian passage and is set about from removing obstruction in the collateral to relieve pain, wind dispelling.
Medical material present Research involved in the present invention is as follows:
The tuber that Diels Stephania Root [another name] Radix Stephaniae Sinicae (Radix Stephaniae Dielsianae), is bled, Stephania cepharatha Hayata, Radix Cissi Kerrii [source] are menispermaceous plants Diels Stephania Root.Autumn, winter excavate, and clean, and dry.[habitats distribution] is distributed in the ground such as Guangxi, Hunan, Guangdong, Guizhou.[nature and flavor] hardship; Cold.[function cures mainly] heat-clearing and toxic substances removing; Eliminating stasis to stop pain.Your Majesty's respiratory tract infection; Pharyngitis; Carbuncle sore; Stomachache; Gastroenteritis; Toothache; Neuralgia; Traumatic injury.[usage and dosage] is for oral administration: decoct soup, 6-15g.External: appropriate, fresh goods is smash deposited.[extracts] " China's book on Chinese herbal medicine "
Narrow leaf Celastrus orbiculatus Thunb. [another name] Celastrus oblanceifolius Wang et Tsoong [source] is root, the stem of Celastraceae plant narrow leaf Celastrus orbiculatus Thunb..Can gather the whole year, and using fresh herb or section are dried.[nature and flavor] are pungent; Bitter; Tepor.[function cures mainly] expelling wind and removing dampness; Blood-activating and qi-promoting; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Traumatic injury; Colicky; Sore swollen toxin; Herpes zoster; Eczema.[usage and dosage] is for oral administration: decoct soup, 9-15g.External: appropriate, root bark levigation dresses; Or with root add water mill juice be coated with.[extracts] " China's book on Chinese herbal medicine "
The stem and leaf that Caulis et Folium hedyotis hedyotideae [another name] has tomentose fevervine herb, pus to see to disappear, abnormal pigmentary deposit on the skin acute diseases such as cholera and sunstroke rattan, gentiana macrophylla grass [source] are dicotyledon medicine Maguireothamnus speciosus Caulis et Folium hedyotis hedyotideae.Can adopt the whole year.[nature and flavor] are sweet light; Cool.[return through] lung; Liver; Kidney channel.[function cures mainly] heat-clearing and toxic substances removing.Main heatstroke; High heat; Intestinal inflammation; Skin eczema; Herpes zoster; Carbuncle pyogenic infections from tumour or sore.[usage and dosage] is for oral administration: decoct soup, 10-30g.External: appropriate, mash external application.[extracts] " China's book on Chinese herbal medicine "
Caulis Trachelospermi [another name] stone dace, alum, outstanding stone, Yun Zhu, sea urchin roe paste, stone consult [source] be leaf bine stem of apocynaceae plant trachelospermum jasminoide.Plant after 3~4 years autumn Mo clip rattan, be cut into 25~30cm long, be bundled into wisp, dry.[nature and flavor] hardship; Pungent; Cold nature.[return through] heart; Liver; The flat removing obstruction in the collateral to relieve pain of kidney channel [function cures mainly]; Heat clearing and blood cooling; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Soreness of waist and knee joint; The contracture of muscle arteries and veins; Laryngopharynx swelling and pain; Furuncle swelling toxin; Traumatic injury; Traumatic hemorrhage.[usage and dosage] is for oral administration: decoct field, 6-15g single can be used to 30g; Infusing drugs in wine, 30-60g; Or enter ball, powder.External: appropriate, grind into powder and dress or smash juice painting.[extracts] " China's book on Chinese herbal medicine "
Herba phylae nodieflorae [another name] Fructus Ananadis comosi grass, prosperous pears grass, Thunder God hammer grass, Herba Phylae Samentosea [source] are the herb of Verbenaceae Phyla nodiflora.Plant and gather the 9-10 month then.Later short year gather 2 times, the 1st time in the 6-7 month, and the 2nd time in the 9-10 month.After gathering, choose roguing grass and clean, using fresh herb or dry.[habitats distribution] is distributed in southwest and Jiangsu, Jiangxi, Fujian, Taiwan, Hubei, Hunan, Guangdong, Guangxi.[nature and flavor] mildly bitter flavor; Cool in nature.[function cures mainly] heat clearing away; Removing toxic substances.Main laryngopharynx swelling and pain; Ulcerative gingivitis; Have loose bowels; Dysentery; Skin sore; Herpes zoster; Eczema; Scabies.[usage and dosage] is for oral administration: decoct soup, fresh goods 30-60g; Or smash juice.External: appropriate, decocting is washed; Or smash deposited.[extracts] " China's book on Chinese herbal medicine "
Herba Blumeae Balsamiferae [another name] Balsamiferou Blumea Herb, the ears of an ox or cow end, wind Chinese mugwort, Ramulus Et Folium Adhatodae Vasicae, Radix Et Rhizoma Rhei, Borneolum Syntheticum Chinese mugwort [source] this product are the herb of feverfew Herba Blumeae Balsamiferae again.Gather in December, first fallen leaves are concentrated, then cutting with the aerial stem of plant of leaf, using fresh herb or dry; Or transport to processing factory's way of distillation and steam to obtain Chinese mugwort powder.[nature and flavor] acrid in the mouth; Micro-hardship; Warm in nature.[function cures mainly] expelling wind and removing dampness; Warming middle-JIAO to stop diarrhea; Promoting blood circulation and detoxication.Main anemofrigid cold; Wind syndrome of head headache; Rheumatic arthralgia; Cold-damp dysentery; Taeniasis; Venom; Traumatic pain; Tinea skin ulcer.[usage and dosage] is for oral administration: decoct soup, and 10-15g, fresh goods doubles.External: appropriate, decoct washing; Or smash deposited.[extracts] " China's book on Chinese herbal medicine "
Olibanum [another name] nipple perfume (or spice), the perfume (or spice) that collapses, Ma Si answer Ji, it pool is fragrant, Moller is fragrant, Du's Lu perfume (or spice) [source] this product is the oleo-gum-resin that the skin zones such as olive subject plant Boswellia carterii, Bao Da Boswellia carterii, wild Boswellia carterii ooze out.Spring, summer all can gather, with spring for the phase of abounding with.While gathering, in skin zone's order incised wound from bottom to top of trunk, and open a fossula, resin is oozed out from wound, in person who lives in exile's ditch, after a few days, converge into stiff solid, can take.Fall within ground person and often adhere to sand impurity, quality is inferior.[nature and flavor] acrid in the mouth; Bitter; Tepor.[return through] heart; Liver; Spleen channel.[function cures mainly] blood-activating and qi-promoting; Inducing menstruation to relieve menalgia; Detumescence and promoting granulation.Main trusted subordinate's pain; Rheumatic arthralgia; Amenorrhea dysmenorrhea; Traumatic injury stasis of blood pain; Swollen ulcer drug; Coagulation of QI-blood; Intestinal carbuncle; The sore being festered and unhealed.[usage and dosage] is for oral administration: decoct soup, 3-10g; Or enter ball, loose.External: appropriate, grind into powder and dress.[extracts] " China's book on Chinese herbal medicine "
Spread and send out the tuber that [another name] Baoshan Radix Aconiti Lateralis Preparata, little black cattle, Radix Aconiti Kusnezoffii, Water Aconitum carmichaeli Debx., mountain Aconitum carmichjaelii Debx. [source] this product are ranunculaceae plant Baoshan Aconitum carmichjaelii Debx..Excavate tuber in autumn, winter, clean, dry.[nature and flavor] acrid in the mouth; Bitter; Hot in nature; Poisonous.[return through] Liver Channel.[function cures mainly] expelling wind and dampness; Removing obstruction in the collateral to relieve pain.Main anemofrigid-damp arthralgia; Headache.[usage and dosage] is for oral administration: decoct soup, 1.5-3g.[extracts] " China's book on Chinese herbal medicine "
Summary of the invention
The present invention aims to provide a kind of Chinese medicine that is used for the treatment of herpes zoster, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing herpes zoster.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine that is used for the treatment of herpes zoster, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: 11 parts of Diels Stephania Roots, 8 parts of narrow leaf Celastrus orbiculatus Thunb.s, 23 parts of Caulis et Folium hedyotis hedyotideaes, 9 parts of Caulis Trachelospermis, 36 parts of Herba phylae nodiefloraes, 12 parts of Herba Blumeae Balsamiferaes, 7 parts of Olibanums, spread send out 2 parts.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Patients with Herpes Zoster 86 examples that outpatient clinic is collected between year April altogether in inventor in JIUYUE, 2011~2013, all meet diagnosis of herpes zoster standard.All patients are divided into treatment group 43 examples and matched group 43 examples at random.The aspect comparisons such as two groups of Genders, age, the course of disease, the state of an illness, difference not statistically significant (P > 0.05), has comparability, in Table 1-table 3.
Table 1 liang group Sex distribution
Group | n | Man | Female | X 2Value | P value |
Treatment group | 43 | 24 | 19 | 0.427 | 0.701 |
Matched group | 43 | 22 | 21 | ? | ? |
Table 2 liang group age distribution (mean ± SD)
Group | n | Age (year) | T value | P value |
Treatment group | 43 | 37.21±16.32 | 0.412 | 0.631 |
Matched group | 43 | 36.75±14.55 | ? | ? |
Course of disease comparison (mean ± SD) before table 3 liang group treatment
Group | n | The course of disease (my god) | T value | P value |
Treatment group | 43 | 5.23±4.51 | 0.518 | 0.672 |
Matched group | 43 | 4.47±3.69 | ? | ? |
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group makes according to specific embodiment 1, every day 3 times, 7 days courses for the treatment of, treats two courses for the treatment of.
The oral ganciclovir of matched group (using according to its description), 7 days courses for the treatment of, treats two courses for the treatment of.
Within after administration 1,3,5,7,14 day, observe, record, follow up a case by regular visits to sings and symptoms and improve situation, mainly observe analgesic time (time that pain obviously alleviates or disappears), stop the bleb time (original vesicle is without the time that increases, occurs without new vesicle), incrustation time (vesicle starts the time of drying up, forming a scab) and post herpetic neuralgia situation occurred.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinical recovery: skin lesion disappears substantially, pain disappears substantially;
Effective: skin lesion major part disappears, and local pain obviously alleviates;
Take a turn for the better: skin lesion part disappears, pain relief;
Invalid: skin lesion and pain are all without obviously alleviating;
Total effective rate adds effective statistics with clinical recovery.
3.2 therapeutic outcome
Two groups of effective pain relievings of patient, only bleb and incrustation time and clinical efficacy are in table 4, table 5.
The table 4 liang effective pain relieving of group patient, only bleb and incrustation time comparison (my god, mean ± SD)
Group | n | Analgesic time | The only bleb time | The incrustation time |
Treatment group | 43 | 4.01±2.13 | 3.59±1.02 | 6.98±1.27 |
Matched group | 43 | 7.57±2.55 | 5.48±1.35 | 7.64±1.34 |
Table 5 liang group Clinical efficacy comparison n (%)
Two groups of effective pain relievings of patient, only bleb and incrustation time and Clinical efficacy comparison have significant difference (P < 0.01)
Two groups of post herpetic neuralgia incidence rates comparison: post herpetic neuralgia appears in treatment group 3 examples (6.98%) and matched group 6 examples (13.95%), two groups of comparing difference significances (P < 0.05).
It is high that visible the present invention is used for the treatment of herpes zoster cure rate, and post herpetic neuralgia incidence rate is low.There is the value of applying.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: 11 grams of Diels Stephania Roots, 8 grams of narrow leaf Celastrus orbiculatus Thunb.s, 23 grams of Caulis et Folium hedyotis hedyotideaes, 9 grams of Caulis Trachelospermis, 36 grams of Herba phylae nodiefloraes, 12 grams of Herba Blumeae Balsamiferaes, 7 grams of Olibanums, spread send out 2 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of one day consumption of normal adult.
Be used for the treatment of herpes zoster.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: 11 grams of Diels Stephania Roots, 8 grams of narrow leaf Celastrus orbiculatus Thunb.s, 23 grams of Caulis et Folium hedyotis hedyotideaes, 9 grams of Caulis Trachelospermis, 36 grams of Herba phylae nodiefloraes, 12 grams of Herba Blumeae Balsamiferaes, 7 grams of Olibanums, spread send out 2 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, pack, must meet the powder of one day consumption of normal adult.
Be used for the treatment of herpes zoster.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 3
Take: 11 grams of Diels Stephania Roots, 8 grams of narrow leaf Celastrus orbiculatus Thunb.s, 23 grams of Caulis et Folium hedyotis hedyotideaes, 9 grams of Caulis Trachelospermis, 36 grams of Herba phylae nodiefloraes, 12 grams of Herba Blumeae Balsamiferaes, 7 grams of Olibanums, spread send out 2 grams; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, must meet the capsule of one day consumption of normal adult.
Be used for the treatment of herpes zoster.Oral, every bu morning, noon and afternoon take for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of herpes zoster, it is characterized in that, it is to be prepared from by the raw medicinal material of following weight proportion: 11 parts of Diels Stephania Roots, 8 parts of narrow leaf Celastrus orbiculatus Thunb.s, 23 parts of Caulis et Folium hedyotis hedyotideaes, 9 parts of Caulis Trachelospermis, 36 parts of Herba phylae nodiefloraes, 12 parts of Herba Blumeae Balsamiferaes, 7 parts of Olibanums, spread send out 2 parts.
2. the Chinese medicine that is used for the treatment of herpes zoster as claimed in claim 1, it is characterized in that, its preparation method is: take: 11 parts of Diels Stephania Roots, 8 parts of narrow leaf Celastrus orbiculatus Thunb.s, 23 parts of Caulis et Folium hedyotis hedyotideaes, 9 parts of Caulis Trachelospermis, 36 parts of Herba phylae nodiefloraes, 12 parts of Herba Blumeae Balsamiferaes, 7 parts of Olibanums, spread send out 2 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. the Chinese medicine that is used for the treatment of herpes zoster as claimed in claim 1, it is characterized in that, its preparation method is: take: 11 parts of Diels Stephania Roots, 8 parts of narrow leaf Celastrus orbiculatus Thunb.s, 23 parts of Caulis et Folium hedyotis hedyotideaes, 9 parts of Caulis Trachelospermis, 36 parts of Herba phylae nodiefloraes, 12 parts of Herba Blumeae Balsamiferaes, 7 parts of Olibanums, spread send out 2 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. the Chinese medicine that is used for the treatment of herpes zoster as claimed in claim 1, it is characterized in that, its preparation method is: take: 11 parts of Diels Stephania Roots, 8 parts of narrow leaf Celastrus orbiculatus Thunb.s, 23 parts of Caulis et Folium hedyotis hedyotideaes, 9 parts of Caulis Trachelospermis, 36 parts of Herba phylae nodiefloraes, 12 parts of Herba Blumeae Balsamiferaes, 7 parts of Olibanums, spread send out 2 parts; Add 6 times of water gagings, decoct 3 times, decoct 1 hour at every turn, merge decoction liquor, concentrated, dry, incapsulate shell, obtain capsule; Above-mentioned part all refers to weight portion.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105168814A (en) * | 2015-09-30 | 2015-12-23 | 张晰 | Traditional Chinese medicine composition for treating herpes zoster ophthalmicus |
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CN103735784A (en) * | 2013-12-16 | 2014-04-23 | 张圣坤 | Lotion for herpes |
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US20080031892A1 (en) * | 2004-07-16 | 2008-02-07 | Medimush A/S | Immune modulating compounds from fungi |
CN103735784A (en) * | 2013-12-16 | 2014-04-23 | 张圣坤 | Lotion for herpes |
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徐明: "《家有妙方》", 31 August 2010, 海峡出版发行集团 * |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105168814A (en) * | 2015-09-30 | 2015-12-23 | 张晰 | Traditional Chinese medicine composition for treating herpes zoster ophthalmicus |
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Application publication date: 20141029 |