CN104971142A - Traditional Chinese medicine for treating viral enteritis - Google Patents
Traditional Chinese medicine for treating viral enteritis Download PDFInfo
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- CN104971142A CN104971142A CN201510346781.4A CN201510346781A CN104971142A CN 104971142 A CN104971142 A CN 104971142A CN 201510346781 A CN201510346781 A CN 201510346781A CN 104971142 A CN104971142 A CN 104971142A
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Abstract
The invention relates to a traditional Chinese medicine for treating viral enteritis. The traditional Chinese medicine for treating viral enteritis is prepared from, by weight, 12 parts of Cyclea hypoglauca (Schauer) Diels, 3 parts of Immature fruit of Medicine Terminalia, 7 parts of Herb of Yellowbell Clematis, 9 parts of Celastrus orbiculatus Thunb., 6 parts of westland dutchmanspipe root, 0.3 parts of Tangut Anisdus Radix and 10 parts of Root of Patent hairy Melastoma. Clinic experiments prove that the viral enteritis can be safely and effectively treated by using the traditional Chinese medicine.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of viral enteritis.
Background technology
Viral enteritis is one group of acute infectious intestinal disease caused by multiple virus.Clinical characters is onset urgency, Nausea and vomiting, stomachache, diarrhoea, passage of watery stools or loose stool, and also can have the symptoms such as heating and general malaise, the course of disease is short, and case fatality rate is low.Caused by various virus, the clinical manifestation of gastroenteritis is substantially similar.The viral species relevant with acute gastroenteritis is more, wherein outbalance, to study more be rotavirus and norwalk virus.In doctor trained in Western medicine, current primary disease there is no specific treatment medicine, adopts diet guide clinical more, and Drug therapy application antiviral, mucosa protective agent, microbial ecological agent, trace element supplement, fluid therapy, correction acidosis etc. are Supporting Therapy to the ill.Chinese medicine thinks this disease mainly caused by gastrointestinal dysfunction and spleen-stomach dysfunction, and the cause of disease mainly contains following several respects, and one is due to the imbalance of patient's chronic dietary; Two is cause weakness of the spleen and stomach because patient's prolonged illness is touching; Three is greedy coolly to sleep in the open, and cold-damp is invaded.Due to stomach receiving food and drink, The spleen has the function to transport and transform nutrients, and weakness of the spleen and stomach is clear QI being mixed up with turbid QI then, stops in humidity hysteresis, can not be received transportation and transformation of water and food, and treatment is the basic rule for the treatment of mainly with " activating the spleen removing dampness ".
Medical material present Research involved in the present invention is as follows:
Radix Ilicis Asprellae rattan [another name] Herba Anoectochili roxburghii, Radix cycleae hypoglaucae, post Eumeces Chinensis, Radix Sophorae Tonkinensis, Jasminum nervosum Lour, the young rattan of clam, JINSUOSHI, unipods Sapium sebiferum (L.) Roxb..The root that [source] is menispermaceae Plant Powder vane rings rattan or rattan.The whole year all can gather, and removes fibrous root or branch and leaf, and clean, cutting, dries.[nature and flavor] are bitter; Cold.[return through] lung; Large intestine; Liver Channel.[function cures mainly] heat-clearing and toxic substances removing; Wind-expelling pain-stopping; Relieving stranguria by diuresis.Main anemopyretic cold; Cough; Laryngopharynx swelling and pain; Diphtheria; Acute toothache; Intestinal is scorching; Dysentery; Urinary tract infection and lithangiuria; Rheumatalgia; Sore swollen toxin; Venom.[usage and dosage] takes orally: decoct soup, 10-30g.[extracts] " China's book on Chinese herbal medicine "
Fructus chebulae immaturus [another name] Tibet Fructus Canarii, FRUCTUS TERMINALIAE IMMATURUS [source] for Combretum Racemosum plant be the young fruit of Combretum Racemosum Fructus Chebulae.To gather the 9-10 month immature young fruit, dry after having one's hair waved.[nature and flavor] bitter in the mouth; Micro-sweet; Puckery; Cold nature.[function cures mainly] clearing away heat and promoting production of body fluid; Liyan jiedu.Main deficiency syndrome diphtheria; Tonsillitis; Bacillary dysentery; Dysentery; Enteritis.[usage and dosage] takes orally: decoct soup, 3-6g; Or buccal.[extracts] " China's book on Chinese herbal medicine "
The herb that Herba Clematidis Glaucae [another name] Radix clematidis floridae, Herba speranskiae tuberculatae, grayish green Radix clematidis floridae [source] are ranunculaceae plant clematis glauca.Herb, summer and autumn taps, and removes weeds, dries.Root, autumn adopts, and clean, cutting, dries.[nature and flavor] are pungent; Temperature.[return through] heart; Stomach warp.[function cures mainly] expelling wind and removing dampness, detoxicating and resolving stagnation of pathogens; Dispelling wind is antipruritic.Main rheumatic arthralgia; Intestinal is scorching; Dysentery; Carbuncle furuncle; Skin pruritus; Snake bite and insect sting.[usage and dosage] takes orally: decoct soup, 6-9g.External: appropriate, smashes deposited; Or endure cream, be coated with; Or decoct soup and wash.[extracts] " China's book on Chinese herbal medicine "
Celastrus orbiculatus Thunb. [another name] Celastrus aceleatus Merr, hang wide whip, rattan that XIANGLONGCAO, Cortex Ampelopsis Aconitifoliae Radicis, great Nan Serpentis, Lobaria pulmonaria (L.) Hoffm., Rhizoma Dioscoreae Nipponicae, old tendon Bovis seu Bubali, Huang Guoteng [source] are Celastraceae plant Celastrus orbiculatus Thunb..Spring, autumn gather, and using fresh herb or cutting are dried.[nature and flavor] are bitter; Pungent; Tepor.[return through] liver; Urinary bladder channel.[function cures mainly] expelling wind and removing dampness; Inducing menstruation to relieve menalgia; Promoting blood circulation and detoxication.Main rheumatic arthritis; Numb limbs and tense tendons, paralysis; Headache; Toothache; Hernia; Dysmenorrhea; Amenorrhea; Infantile convulsion; Osteopatia sprain; Dysentery; Acute filthy disease; Herpes zoster.[usage and dosage] takes orally: decoct soup, 9-10g; Or infusing drugs in wine.[extracts] " China's book on Chinese herbal medicine "
The tuber that Aristolochia westlandii Hemsl [source] is aristolochiaceae plant Aristolochia Versicolar S. m. hwang.Summer, autumn, winter excavate, and clean, cutting, dries.[habitats distribution] is distributed in the ground such as Guangdong, Guangxi, Yunnan.[nature and flavor] are bitter; Cold.[function cures mainly] heat-clearing and toxic substances removing; Reducing swelling and alleviating pain.Main enteritis, diarrhea; Bacillary dysentery; Laryngopharynx swelling and pain; Parotitis; Scrofula; Acute mastitis; Eczema.[usage and dosage] takes orally: decoct soup, 3-10g.External: appropriate, smashes deposited.[extracts] " China's book on Chinese herbal medicine "
Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) [another name] Anisodus carniolicoides C.Y.Wu et C.Chen, stinking nightshade, Camphor tree willow, Camphor tree willow join the root that [source] this product is plant of Solanaceae Radix Anisodi Tangutici.The 9-10 month excavates, and washes away silt, removing crust, fibrous root, and section is dried, and grinds, for subsequent use after processed.[nature and flavor] bitter in the mouth; Pungent; Warm in nature.[function cures mainly] analgesia spasmolytic.Main urgency; Chronic gastroenteritis; Gastral cavity abdomen spasm and pain; Ascariasis of biliary tract; Cholelithiasis; Ulcer sore pain; Traumatic injury; Fracture.[usage and dosage] takes orally: grind into powder, 0.3-0.5g; Or tincture, each 0.6-1.5g, every day 3 times.External: appropriate, grinds into powder and to spread or boiled water dresses.[extracts] " China's book on Chinese herbal medicine "
Radix Melastomatis normalis [another name] false bean is harvested, leopard tooth youth, the red ground in stone tiger, sky are white, opening Fructus Jujubae, white quick-fried tooth youth, Flos Rhododendri Delavayi, caddy leaf [source] are root or the leaf that Melastomateae plants opens up hair Herba Melastomatis Candii.Root all can be excavated the whole year, cleans, and section, dries.Leaf was gathered in the 6-7 month, using fresh herb or dry.[nature and flavor] bitter in the mouth; Puckery; Cool in nature.[function cures mainly] circulation of qi promoting dampness removing; Removing stasis to stop bleeding; Removing toxic substances.Main abdominal distention, enteritis, dysentery, hepatitis, stranguria with turbid discharge, hemoptysis, spits blood, epistaxis; Have blood in stool; Menorrhagia; Dysmenorrhea; Leucorrhea; Colicky; Thromboangiitis; Skin infection festers; Herpes zoster; Treating swelling and pain by traumatic injury.[usage and dosage] takes orally: decoct soup, 9-15g; Or infusing drugs in wine.External: appropriate, smashes deposited, strand juice and is coated with or grinds into powder deposited.[extracts] " China's book on Chinese herbal medicine "
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of viral enteritis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective Cure Viruses enteritis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of viral enteritis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: 12 parts, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 parts, Herba Clematidis Glaucae 7 parts, Celastrus orbiculatus Thunb. 9 parts, Aristolochia westlandii Hemsl 6 parts, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 part, Radix Melastomatis normalis 10 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects viral enteritis patient 90 example of outpatient clinic altogether between in May ,-2013 in April, 2011, all meet viral enteritis diagnostic criteria.All patients are divided at random treatment group 44 example and matched group 45 example.The aspects such as two groups of patient ages, sex, courses of disease compare in Table 1-table 3.
Table 1 liang group patient age (year) compare
Table 2 liang group gender comparison
The table 3 liang group course of disease (moon) compares
Compare P by the visible two groups of patient's basic documents of table 1-table 3 and be all greater than 0.05, namely two groups of patient clinical basic document there was no significant differences, have comparability.
1.2 accurate disconnected standards
" new Chinese medicine treatment viral enteritis) guideline of clinical investigations " with reference to Ministry of Health of the People's Republic of China develops and publishes:
Primary symptom: stool water sample, or as egg style, rush down urgently lower, amount is many, day row more than ten times, abnormal smells from the patient is smelly dirty, poor appetite lack of appetite, and body is tired weak, thirst and drinking, irritated, or accompanies nausea.
Secondary disease: heating oliguria with yellow urine, red tongue, yellow and greasy fur, fingerprint is purple, and Chinese medical discrimination is damp-heat syndrome.
1.3 inclusive criteria
(1) the Western medicine diagnose standard of viral enteritis is met;
(2) diagnostic criteria of traditional Chinese medical science viral enteritis is met;
(3) with heating (body temperature >=37.4 DEG C);
(4) antiviral agents, mucosa protective agent, microbial ecological agent, antidiarrheal was not used to treat before the treatment;
(5) good compliance is had to clinical observation and evaluation.
1.4 exclusion standard
(1) the Western medicine diagnose standard person of viral enteritis is not met;
(2) accept associated treatment, diagnosis or efficacy determination person may be affected;
(3) allergy sufferers is had to this medicine prescription Chinese medicine composition;
(4) severe dehydration companion shock or with severe systemic disease patients such as liver, kidney, the heart, blood systems;
(5) other infectious diarrheas patient except rotavirus infection.
1.5 reject standard
(1) violate inclusive criteria when case is selected in, should carry out clinical trial person;
(2) merge and take the medicine that this programme forbids taking, the person that correctly cannot judge efficacy and saferry;
(3) enter without any data after group, person lost to follow-up for some reason.
1.6 stop or the standard that comes off
(1) there is serious quick reaction or serious adverse reaction person occurred in experimenter during studying;
(2) do not clearly state, but not medication person again.
1.7 Statistical Principles coming off case
(1) if untoward reaction occurs and comes off, then untoward reaction statistics should be listed in;
(2) because of invalid and self falling person, curative effect statistics is listed in;
(3) namely fully recover the course for the treatment of for discontented 1, be not classified as the case that comes off;
(4) effective in therapeutic process, but the whole course for the treatment of can not be completed, then do not list curative effect statistics in; To the case come off, intentional analysis be made.
2, test method
2.1 Therapeutic Method
The decoct that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every day 3 times.2 weeks courses for the treatment of.
Matched group Oral Bifidobacterium live triple falls apart (Birid Triple Viable), and (Xinyi, Shanghai pharmaceutical factory company limited, uses according to its description, 2 weeks courses for the treatment of.
Duration of test all experimenters forbidding is to the medicative Chinese and western drugs of viral enteritis tool and other Therapeutic Method, run into merging disease and must take other drug treatment, the information such as medicine name (comprising trade name and chemical name), consumption, Slurry pump, access times and time must be recorded in case report form, analyzed during summary and report.
3, criterion of therapeutical effect and therapeutic outcome
3.1 clinical cardinal symptoms and sign weight rank scores standard and individual event curative effect determinate standard
Clinical cardinal symptom and sign weight rank scores standard are in table 4.
Table 4 viral enteritis tcm symptom scalar quantization table
3.2 clinical total effects criterion
The criterion of therapeutical effect of working out with reference to Chinese Medical Association's the 7th national disease for digest academic conference " National Consensus to China's diagnosis status of inflammatory bowel disease treatment specification " carries out efficacy determination from intending, specific as follows:
Recovery from illness: clinical symptoms all disappears, anus mirror and enteroscopy intestinal mucosa recover normal, and stool routine examination microscopy is normal.
Effective: clinical symptoms disappears substantially, anus inspection and the reaction of enteroscopy intestinal mucosal surface mild inflammation, congested, edema obviously disappears, and stool routine examination microscopy is normal.
Effective: clinical cardinal symptom partial disappearance or alleviate, anoscopy intestinal mucosal surface congestion and edema, there is hemorrhagic focus local, and ulcer number or ulcer surface reduce or reduce, and stool microscopy is even pus cell or erythrocyte, leukocyte and macrophage.
Invalid: the inspection of clinical symptoms, anus and enteroscopy are without significant change or add severe one.
Total effective rate=(recovery from illness+effective+effectively)/total number of cases * 100%.
3.2.1 before and after each individual event symptom treatment, total mark compares and individual event comparitive study
Before and after two groups of patient treatments, cardinal symptom total mark compares, before after comparing treatment group treatment in two groups of groups, total mark is significantly less than treatment (P < 0.05), total mark there was no significant difference (P > 0.05) front with treatment after treatment of control group; Two groups of total mark there was no significant differences (P > 0.05) before comparison therapy between group, after treatment, treatment group integration is starkly lower than matched group (P < 0.05), the results are shown in Table 5.
The total mark change that the two groups of patient's cardinal symptom signs in front and back treated by table 5 is compared
3.2.2 two groups of clinical total effectses compare
Two groups of clinical total effectses compare in table 6.
The table 6 liang clinical total effects of group compares
Two groups of therapeutic outcomes are through X 2 test, and P=0.04 < 0.05, x2=8.07, it is high that visible i.e. the present invention is used for the treatment of proctitis cure rate, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: 12 grams, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 grams, Herba Clematidis Glaucae 7 grams, Celastrus orbiculatus Thunb. 9 grams, Aristolochia westlandii Hemsl 6 grams, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 gram, Radix Melastomatis normalis 10 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of viral enteritis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 2
Take: 12 grams, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 grams, Herba Clematidis Glaucae 7 grams, Celastrus orbiculatus Thunb. 9 grams, Aristolochia westlandii Hemsl 6 grams, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 gram, Radix Melastomatis normalis 10 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of viral enteritis.Oral, every bu morning, noon and afternoon take for three times.
Specific embodiment 3
Take: 12 grams, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 grams, Herba Clematidis Glaucae 7 grams, Celastrus orbiculatus Thunb. 9 grams, Aristolochia westlandii Hemsl 6 grams, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 gram, Radix Melastomatis normalis 10 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of viral enteritis.Oral, every bu morning, noon and afternoon take for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of viral enteritis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: 12 parts, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 parts, Herba Clematidis Glaucae 7 parts, Celastrus orbiculatus Thunb. 9 parts, Aristolochia westlandii Hemsl 6 parts, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 part, Radix Melastomatis normalis 10 parts.
2. a kind of Chinese medicine being used for the treatment of viral enteritis as claimed in claim 1, it is characterized in that, its preparation method is: take: 12 parts, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 parts, Herba Clematidis Glaucae 7 parts, Celastrus orbiculatus Thunb. 9 parts, Aristolochia westlandii Hemsl 6 parts, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 part, Radix Melastomatis normalis 10 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of viral enteritis as claimed in claim 1, it is characterized in that, its preparation method is: take: 12 parts, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 parts, Herba Clematidis Glaucae 7 parts, Celastrus orbiculatus Thunb. 9 parts, Aristolochia westlandii Hemsl 6 parts, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 part, Radix Melastomatis normalis 10 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of viral enteritis as claimed in claim 1, it is characterized in that, its preparation method is: take: 12 parts, Radix Ilicis Asprellae rattan, Fructus chebulae immaturus 3 parts, Herba Clematidis Glaucae 7 parts, Celastrus orbiculatus Thunb. 9 parts, Aristolochia westlandii Hemsl 6 parts, Radix seu Semen Anisodi tangutici (Radix Anisodi Tangutici) 0.3 part, Radix Melastomatis normalis 10 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1157169A (en) * | 1996-10-31 | 1997-08-20 | 刘铁兴 | Chinese medicine preparation for curing viral enteritis |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1157169A (en) * | 1996-10-31 | 1997-08-20 | 刘铁兴 | Chinese medicine preparation for curing viral enteritis |
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