CN103989841A

CN103989841A - Pharmaceutical composition for treatment of epidemic hemorrhagic fever

Info

Publication number: CN103989841A
Application number: CN201410186004.3A
Authority: CN
Inventors: 宫占风
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-04-29
Filing date: 2014-04-29
Publication date: 2014-08-20

Abstract

The invention relates to a pharmaceutical composition for treatment of epidemic hemorrhagic fever, and is characterized in that the pharmaceutical composition is prepared from the following raw medicinal materials by weight: 6-9 g of scutellaria baicalensis, 2-4 g of radix bupleuri, 1-3 g of junci medulla, 0.5-1 g of borneolum luodian, 1-3 g of fewflower lysionotus herb, 6-9 g of strophanthus divaricatus, 5-9 g of folium sauropi, 6-8 g of ilex purpurea hassk, 6-8 g of herba laggerae, 6-8 g of male fern rhizome, 6-9 g of radix rehmanniae, 2-3 g of folium picrasmae quassioidis, 5-8 g of sophora flower, and 6-9 g of plantain herb. The pharmaceutical composition has the beneficial effects of clearing heat, detoxifying, cooling blood, dispelling dryness and heat, reducing bleeding in skin, improving renal functions, and expelling toxins. The pharmaceutical composition is often used for diagnosis and treatment based on an overall analysis according to different types of syndromes in clinic. The pharmaceutical composition is fast in curative effect and high in cure rate.

Description

A kind of pharmaceutical composition for the treatment of epidemic hemorrhagic fever

Technical field

The present invention relates to a kind of pharmaceutical composition for the treatment of epidemic hemorrhagic fever.

Background technology

As everyone knows, epidemic hemorrhagic fever claims again hemorrhagic fever with renal syndrome, is the disease of natural focus being caused by epidemic haemorrhagic fever virus, and popular wide, sb.'s sickness becomes critical, and case fatality rate is high, very harmful.Human virus's hemorrhagic fever has 13 kinds in the world, have according to this disease kidney harmless, be divided into have kidney undermine without kidney damage two large classes.Because specific serum is learned establishment and the etiologic solution diagnosed, unified the naming as hemorrhagic fever with renal syndrome of nineteen eighty-two World Health Organization (WHO).Existing China still continues to use the name of disease of epidemic hemorrhagic fever.Route of transmission: (1) respiratory tract; (2) digestive tract; (3) contact transmission; (4) mother-to-baby transmission; (5) arthropod-borne.The traditional Chinese medical science is thought: for heresy enters from outward, above invade in lung, stream lie prostrate under, poison kidney yin, strongly fragrant gesture of a specified duration is opened, malicious evil outgoing, good and evil are anti-mutually, form victory or defeat conversion process.Evil Yu Wei divides, heat is closed in edema caused by disorder of QI, hot stasis blocking.

Summary of the invention

The beneficial effect of this invention Chinese medicine is: heat-clearing and toxic substances removing, removing heat from blood, dispel scorching, reduce dermatorrhagia, improve renal function, discharge toxin.Clinical often according to the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of different disease type.

Technical problem to be solved by this invention is in order to overcome technical deficiency, provides a kind of good effect, short treating period, cure rate high, and a kind of pharmaceutical composition for the treatment of epidemic hemorrhagic fever having no side effect.

For realizing above object, treat a pharmaceutical composition for epidemic hemorrhagic fever, it is characterized in that being made by the crude drug of following weight proportion: Radix Scutellariae 6～9g, Radix Bupleuri 2～4g, Medulla Junci 1～3g, Blumeae preparatum Tabellae 0.5～1g, Herba Lysionoti Pauciflori 1～3g, Folium Microcoris paniculatae 6～9g, Folium Sauropi 5～9g, Ilex purpurea Hassk.[I.chinensis Sims 6～8g, Wingedtooth Laggera Herb 6～8g, Rhizoma Dryopteris Crassirhizomatis 6～8g, Radix Rehmanniae 6～9g, Ramulus Et Folium Picrasmae leaf 2～3g, Flos Sophorae 5～8g, Herba Plantaginis 6～9g.

Scutellariae,radix in Chinese medicine of the present invention is a kind of medical herbs, bitter in the mouth, cold in nature, and heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.That modern study has is antibacterial, antiviral, antiinflammatory antiallergic action, protects the liver, function of gallbladder promoting, antioxidative effect.Join the logical conditioning table of Radix Bupleuri.Medulla Junci sweet in the mouth, light, cold nature.GUIXIN, lung, small intestine meridian.Function with cure mainly: clearing away heart-fire, diuresis.For vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue." detailed outline ": heart-fire is fallen, hemostasis, ventilation, loose swollen, quench the thirst.Folium Artemisiae Argyi acrid in the mouth, hardship, cold nature.GUIXIN, spleen, lung meridian.Function with cure mainly: the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, middle plucked instrument stupor, conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.Herba Lysionoti Pauciflori bitter in the mouth, warm in nature, return lung meridian.Preventing phlegm from forming and stopping coughing, hard masses softening and resolving.Folium Microcoris paniculatae promoting digestion and removing stagnation, clearing away heat-damp and promoting diuresis.Folium Sauropi sweet in the mouth, light, property is flat.Attach to the lung and stomach meridians.Function with cure mainly: nourishing the lung to arrest cough, relieving constipation.For xeropulmonary cough, pharyngalgia aphonia, constipation.Ilex purpurea Hassk.[I.chinensis Sims bitter in the mouth, puckery, cool in nature.Return lung large intestine, urinary bladder channel.Function with cure mainly: heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling.For cough due to lung-heat, laryngopharynx swelling and pain, dysentery, hypochondriac pain, pyretic stranguria; Externally treating burns and scalds, skin ulcer.Wingedtooth Laggera Herb acrid in the mouth, hardship, cold in nature; Poisonous.Return lung meridian.Function with cure mainly: heat-clearing and toxic substances removing, eliminating phlegm and stopping cough.For anemopyretic cold, laryngopharynx swelling and pain, cough due to lung-heat.Rhizoma Dryopteris Crassirhizomatis bitter in the mouth, cold nature.Return liver, stomach warp.Function with cure mainly: heat-clearing and toxic substances removing, anthelmintic.For abdominal pain due to worm stagnation, skin infection.Metrorrhagia.Radix Rehmanniae sweet in the mouth, cold in nature.GUIXIN, liver, kidney channel.Function with cure mainly: there is clearing away heat and cooling blood effect for the warm febrile disease blood of joining the army, high fever coma, xerostomia crimson tongue." book on Chinese herbal medicine performance ": clean ancient cloud: Radix Rehmanniae is cold in nature, bitter in the mouth.Removing heat from blood is enriched blood, and the kidney invigorating water kidney-YIN being deficient is controlled few cloudy heat in the heart interior.Ramulus Et Folium Picrasmae leaf bitter in the mouth, cold in nature; Return lung, large intestine channel.Function with cure mainly: heat clearing away, damp eliminating, removing toxic substances.For anemopyretic cold, laryngopharynx swelling and pain, diarrhoea dysentery, eczema, furuncle, venom.Herba Plantaginis sweet in the mouth, cold in nature.Return liver, kidney, lung, small intestine meridian.Function with cure mainly: clearing away heat and promoting diuresis, eliminate the phlegm, removing heat from blood, removing toxic substances.For edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.Flos Sophorae bitter in the mouth, cold nature, return liver, large intestine channel; Enter blood and hold back and fall, body is slightly loose; There is cooling blood for hemostasis, effect of purging liver-fire; Cure mainly discharging fresh blood stool, hemorrhoidal bleeding, dysentery, hematuria, stranguria with blood, metrorrhagia, spits blood, epistaxis, liver-fire headache, conjunctival congestion and swelling pain, sore throat, aphonia, the above medicine of ulcer sores matches, brings out the best in each other.

The present invention follows the prescriptions principle of the traditional Chinese medical science, and through clinical application for many years checking, effective percentage is that more than 90% cure rate is more than 85%.

Detailed description of the invention

Below in conjunction with implementing case, the invention will be further described:

Embodiment 1: a kind of pharmaceutical composition for the treatment of epidemic hemorrhagic fever, treat a pharmaceutical composition for epidemic hemorrhagic fever, it is characterized in that being made by the crude drug of following weight proportion: Radix Scutellariae 6～9g, Radix Bupleuri 2～4g, Medulla Junci 1～3g, Blumeae preparatum Tabellae 0.5～1g, Herba Lysionoti Pauciflori 1～3g, Folium Microcoris paniculatae 6～9g, Folium Sauropi 5～9g, Ilex purpurea Hassk.[I.chinensis Sims 6～8g, Wingedtooth Laggera Herb 6～8g, Rhizoma Dryopteris Crassirhizomatis 6～8g, Radix Rehmanniae 6～9g, Ramulus Et Folium Picrasmae leaf 2～3g, Flos Sophorae 5～8g, Herba Plantaginis 6～9g.

Embodiment 2: a kind of pharmaceutical composition for the treatment of epidemic hemorrhagic fever, is characterized in that by following proportioning weighting raw materials thing: Radix Scutellariae 9g, Radix Bupleuri 4g, Medulla Junci 2g, Blumeae preparatum Tabellae 0.5g, Herba Lysionoti Pauciflori 2g, Folium Microcoris paniculatae 6g, Folium Sauropi 6g, Ilex purpurea Hassk.[I.chinensis Sims 6g, Wingedtooth Laggera Herb 6g, Rhizoma Dryopteris Crassirhizomatis 6g, Radix Rehmanniae 9g, Ramulus Et Folium Picrasmae leaf 2g, Flos Sophorae 6g, Herba Plantaginis 8g.

Clinical efficacy is summed up

One, physical data: Chinese medicine of the present invention, application for the treatment of epidemic hemorrhagic fever 62 examples clinically for many years, wherein male's 38 examples, women's 34 examples, age 18-62 year

Two, diagnostic criteria: 1. suspected case: epidemic-stricken area and epidemic season, febris acuta, the exhaustion of whole body height, weak, headache, eye socket pain, lumbago, face, neck, upper breast flushing person, or companion's oliguria, hypotension.2. confirmed cases: the 1. hemorrhage sign of skin mucosa, end is thrombocytopenia slightly, occurs atypical lymphocyte, urine protein positive.2. nosetiology or serologic test obtain positive findings.Routine urinalysis: sick day of urine protein the 2nd can occur, 4th～6 sick day urine protein are often reached.There are a large amount of urine protein suddenly, helpful to diagnosing.In some cases urine, occur membranoid substance, this is the condensation product that a large amount of urine protein mix mutually with erythrocyte and Exfoliative cells.Antigen checks: viral separating immune fluorescence or ELISA method, gold colloidal rule is more responsive.Detection of specific antibody etc.

Three, method of administration: the dense 200ml of decocting that adds water, point morning, evening take orally for twice,

Four, curative effect judging standard:

Cure: clinical symptoms disappears completely.

Take a turn for the better: clinical symptoms takes a turn for the better.

Invalid: the state of an illness has no and takes a turn for the better or increase the weight of.

Five, therapeutic effect: clinical application for many years, effective percentage 100% by statistics, cure rate is more than 85%.There is death or complication and sequela without 1 example.

Six, model case:

1, open X, man, 25 years old.Spring in 2009 is medical, main suit's febris acuta, and the exhaustion of whole body height, weak, headache, eye socket pain, lumbago, face, neck, upper breast flushing person, or accompany oliguria 3 days, within 1 week, still repeatedly there are petechia, oliguria through hospitalization.Lab testing: atypical lymphocyte.Patient requires with 10 doses, Chinese medicine of the present invention, and clinical symptoms disappears completely, follows up a case by regular visits to not recurrence again and complication and sequela after March.

2, king XX, female, 42 years old.In June, 2011 is medical, main suit's febris acuta, and the exhaustion of whole body height, weak, headache, eye socket pain, lumbago, face, neck, upper breast flushing person, or accompany oliguria 3 days, within 1 week, still repeatedly there are petechia, oliguria through hospitalization.Lab testing: atypical lymphocyte, occurs membranoid substance in urine protein positive and urine.Patient requires to take 20 doses, Chinese medicine of the present invention, and 1 clinical symptoms disappears completely, follows up a case by regular visits to not recurrence again and complication and sequela after March.

3, Lee X, female, 49 years old.Main suit's febris acuta, the exhaustion of whole body height, weak, headache, eye socket pain, lumbago, face, neck, upper breast flushing person, or accompany oliguria 3 days, within 1 week, still repeatedly there is petechia through hospitalization.Lab testing: atypical lymphocyte, occurs membranoid substance in urine protein positive and urine.Patient requires to take 20 doses, Chinese medicine of the present invention, and clinical symptoms disappears completely, follows up a case by regular visits to not recurrence again and complication and sequela after March.

Claims

1. treat a pharmaceutical composition for epidemic hemorrhagic fever, it is characterized in that being made by the crude drug of following weight proportion: Radix Scutellariae 6～9g, Radix Bupleuri 2～4g, Medulla Junci 1～3g, Blumeae preparatum Tabellae 0.5～1g, Herba Lysionoti Pauciflori 1～3g, Folium Microcoris paniculatae 6～9g, Folium Sauropi 5～9g, Ilex purpurea Hassk.[I.chinensis Sims 6～8g, Wingedtooth Laggera Herb 6～8g, Rhizoma Dryopteris Crassirhizomatis 6～8g, Radix Rehmanniae 6～9g, Ramulus Et Folium Picrasmae leaf 2～3g, Flos Sophorae 5～8g, Herba Plantaginis 6～9g.