CN105168763A - Traditional Chinese medicine treating herpes simplex keratitis - Google Patents
Traditional Chinese medicine treating herpes simplex keratitis Download PDFInfo
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- CN105168763A CN105168763A CN201510527544.8A CN201510527544A CN105168763A CN 105168763 A CN105168763 A CN 105168763A CN 201510527544 A CN201510527544 A CN 201510527544A CN 105168763 A CN105168763 A CN 105168763A
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Abstract
The invention relates to a traditional Chinese medicine treating herpes simplex keratitis. The traditional Chinese medicine is prepared from the following raw medicinal materials in parts by weight: 0.6 part of radix.et rhizom veratri japonici, 9 parts of sun euphorbia herb, 3 parts of horse bezoar, 10 parts of indigo plant seed, 2 parts of quercus semicarpifolia Smith, 30 parts of fiddle-leaf fig root, 10 parts of tree-of-heaven ailanthus bark, and 12 parts of naked-flower beauty-berry. Clinic experiments prove that the traditional Chinese medicine is capable of safely effectively treating herpes simplex keratitis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of herpes simplex keratitis.
Background technology
Herpes simplex keratitis (HSK) to be common be also one of more serious infectious keratopathy, its sickness rate has and obviously rises and aggravation trend in recent years.May be relevant with the extensive use of corticosteroid and immunosuppressant, also may be virus morph make aggressivity strengthen caused by.This genus of cornea is transparent, once ill, then its transparency changes, and there is blurred vision in the normal main suit of patient.This disease is generally along nervi trigeminus morbidity, and diseased region is invaded comparatively dark, and it feels to go down, but because of the adjacent tissue of inflammatory stimulus keratopathy, therefore irritation is still more obvious.Viral keratitis, the course of disease herds length, more after and easily recur.Often can react with tunica uvea, even occur iridocyclitis, hypopyon, or secondary glaucoma, be one of comparatively common clinically diseases causing blindness.Herpes simplex keratitis belongs to the categories such as " dendritic keratitis ", " keratomalacia " of motherland's medical science.Primary disease belongs to wind wheel disease, wind wheel planted agent liver and gall, therefore the formation of primary disease is correlated with more than liver and gall.All affection due to external wind and heat (wind and cold) poison is evil, endogenous cause of ill liver fire exuberance, and wind-fire pyretic toxicity is fought mutually, above attacks in order; Or taste accumulate long-pending damp and hot, stifling black eyeball; Or the hepatic and renal YIN deficiency, hyperactivity of deficient fire, all can cause this sick.Primary disease is more with heat syndrome excess syndrome, should carefully distinguish by detailed survey.As cataracta is floated tender, state of an illness the lighter, mostly is wind-heat of liver channel; Cataracta yellow skin, the dark large person of collapse, mostly is liver and gall excess-fire; Cataracta is flickering, and recurrent exerbation person, mostly is the hepatic and renal YIN deficiency.
Medical material present Research involved in the present invention is as follows:
Seven lis of pellet [another name] human hairs, Rhizoma et radix veratri (Radix Rhizoma Veratri).[source] medical material Ji Yuan: be rhizome and the root of the black purple Rhizoma et radix veratri (Radix Rhizoma Veratri) of liliaceous plant.Gather and store: summer, autumn excavate, except defoliation, cleaning, dry or using fresh herb.[nature and flavor] are pungent; Bitter; Cold; [function cures mainly] inducing vomiting; Dissipating blood stasis; Pain relieving; Parasite killing.Main apoplexy; Demented sputum gushes Sheng; Traumatic injury congestive edema; Scabies.[usage and dosage] takes orally: decoct soup, 0.3 ~ 0.6g.[attention] is not taken by pregnant women.Can not with all ginsengs, Herba Asari, Radix Paeoniae compatibility.[extracts] " China's book on Chinese herbal medicine ".
Herba Euphorbiae Helioscopiae [another name] paint stem, Herba Polygoni nepalensis, tendencies Ganoderma, tendencies grass, greenery LVHUA grass, sunshade is careless, five lamps, WUDUOYUN, white race silkweed, 5 grass, five lamp holder grass, Herba Euphorbiae Helioscopiae, swollen hands, careless eye, amanita phalloides, Rhizoma Arisaematis, silkweed, RADIX EUPHORBIAE PEKINENSIS, gagger umbrella, Herba Peristrophes, turnsole, euphorbia peplus.[source] medical material Ji Yuan: be the herb of euphorbia plant Herba Euphorbiae Helioscopiae.Gather and store: gathering when the 4-5 month blooms, removing root and silt, dry.[nature and flavor] acrid in the mouth; Bitter; Cold nature; [return through] large intestine; Small intestinal; Spleen; Lung meridian.[function cures mainly] line water detumescence; Preventing phlegm from forming and stopping coughing; Removing toxic substances parasite killing.Cure mainly edematous asthma; Phlegm retention is breathed with cough malaria; Bacillary dysentery; Scrofula; Tuberculous fistula; Osteomyelitis.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] asthenia of qi and blood person is forbidden.[extracts] " China's book on Chinese herbal medicine ".
Calculus Equi [another name] Preserved-fish Da, CALCULUS EQUI.[source] medical material Ji Yuan: be equine species horse gastrointestinal tract calculus.Gather and store: the storage mode of adopting of Calculus Equi roughly has: take out gastrointestinal tract calculus after 1. killing horse; 2. in calculus morbidity district higher, north, from the feces that horse is discharged, calculus is found; 3. calculus is found when the operation of lithogenous colic.The calculus of taking out clear water is cleaned, or auspicious boiled water boils several minutes (after boiling water, easily dry), dries or dries.[nature and flavor] sweet in the mouth; Salty; Micro-hardship; Cool in nature; [return through] heart; Liver Channel .[function cures mainly] relieving convulsionly to reduce phlegm; Heat-clearing and toxic substances removing.Main infantile convulsion is demented; The hot coma of expectorant; Hematemesis and epistaxis; Phlegm-heat cough; Malignant boil toxic swelling.[usage and dosage] takes orally: decoct soup, 0.3 ~ 3g.[attention] invasion by pathogenic cold phlegm-damp person avoids use.[extracts] " China's book on Chinese herbal medicine ".
Fructus polygoni tinctorii [another name] Lan Zi, Folium Isatidis are real in, Indigo Naturalis.[source] medical material Ji Yuan: be the fruit of polygonaceae plant polygonum tinctorium ait..Gather and store: gathering during fruit maturation in autumn, removing impurity, dries.[nature and flavor] are sweet; Bitter; Cold in nature.[return through] Liver Channel.[function cures mainly] heat clearing away; Removing heat from blood; Removing toxic substances.The high heat of main epidemic febrile disease; Tell nosebleed; Send out speckle; Laryngopharynx swelling and pain; Furuncle and phyma; Innominate toxic swelling; Infantile malnutrition phagedenoma; Honeybee insect sting.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[attention] deficiency and coldness people and chronic diarrhea fear of cold, feel in abdomen that cold person does not take.[extracts] " China's book on Chinese herbal medicine ".
Extract Querci semicarpifoliae Folium [source] medical material Ji Yuan: the condensed cream that the leaf for Fagaceae high mountain oak decocts.Gather and store: the whole year all can picking leaves.Get leaf to drop in boiling water, boil 30-45min, then get young leaves as above method, become sticky shape to boiling water, precipitation concentration becomes cream.[nature and flavor] are bitter; Puckery; Property is put down.[function cures mainly] heat-clearing and toxic substances removing.Control the dysentery of intermingling cold and heat, enteritis and asthma.Seed also can be used as medicine, and function is identical.[usage and dosage] takes orally: decoct soup, 1 ~ 2g.[extracts] " China's book on Chinese herbal medicine ".
Radix fici panduratae [another name] Ramulus et Folium Mussaendae Pubescentis, Syringa pinnatifolia Hemsl., Clausena excavata Burm.f., car pusher enter stone, Niu Genzi [source] medical material Ji Yuan: be root, the leaf of moraceae plants Radix fici panduratae.Gather and store: root, the whole year can adopt, and autumn is good; Leaf, summer, autumn adopt.Using fresh herb or dry.[nature and flavor] sweet in the mouth, micro-pungent, property flat [return through] return spleen, kidney, liver three warp.[function cures mainly] expelling wind and removing dampness; Removing toxic substances and promoting subsidence of swelling; Promoting blood circulation to restore menstrual flow.Main air pain of dampness syndrome; Yellow cellulitis; Malaria; Pertussis; Galactostasis; Acute mastitis; Dysmenorrhea; Amenorrhea; Carbuncle furuncle and phyma pain; Traumatic injury; Venom [usage and dosage] takes orally: decoct soup, 30 ~ 60g.[extracts] " China's book on Chinese herbal medicine ".
Cortex Ailanthi [another name] tree of heaven skin, ailanthus altissima (mill.) swingle skin, bitter Cortex Ailanthi.[source] root for quassia ailanthus altissima (mill.) swingle or the endothelium of cadre.Spring gathers, and takes tree root, scrapes off outside rough bark, beats it gently with wooden stick, make skin zone and woody part loose from, then strip endothelium, face upward and dry; Or strip dried bark.[nature and flavor] are bitter, cold.[return through] GUIXIN, lung, spleen three warp.[function cures mainly] heat extraction, dampness, astringing intestine to stop diarrhea, hemostasis, parasite killing.Control chronic dysentery, chronic diarrhea, discharging fresh blood stool, metrorrhagia, leukorrhagia, seminal emission, nebulousurine, ascarid.[usage and dosage] takes orally: decoct soup, 6 ~ 9g.Person is unavailable for [attention] Deficiency and coldness of spleen and stomach, and metrorrhagia and leukorrhagia belongs to the Kidney-Yin empty person of kidney man and also avoids it, on foot dry therefore also with it.All dysentery pneumatosis are not use up person and also should not hurriedly be used.[extracts] " China's book on Chinese herbal medicine ".
Folium et Ramulus Callicarpae nudiflorae [another name] successively red, meal soup leaf, crafty man's medicine, large Strepopelia orientalis rice, spend tea in vain.The leaf with twig that [source] is Verbenaceae Callicarpa nudiflora, gathers and stores: summer, autumn gather, and dry and grind into powder.[nature and flavor] are puckery micro-arduous; Flat.[return through] GUIXIN warp.[function cures mainly] dissipating blood stasis stops blooding; Removing toxic substances and promoting subsidence of swelling.Main epistaxis; Hemoptysis; Spit blood; Have blood in stool; Traumatic injury congestive edema; Traumatic hemorrhage; Burn due to hot liquid or fire; Sore festers.[usage and dosage] takes orally: decoct soup, 15 ~ 30.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of herpes simplex keratitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing herpes simplex keratitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of herpes simplex keratitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: seven lis of pellets 0.6 part, Herba Euphorbiae Helioscopiae 9 parts, Calculus Equi 3 parts, Fructus polygoni tinctorii 10 parts, Extract Querci semicarpifoliae Folium 2 parts, Radix fici panduratae 30 parts, Cortex Ailanthi 10 parts, Folium et Ramulus Callicarpae nudiflorae 12 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and Patients with Herpes Simplex Keratitis MAO 116 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 60 example and matched group 56 example at random, 22 ~ 45 years old treatment group age; 21 ~ 45 years old matched group age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national herpes simplex keratitis clinical speciality:
1. premorbid has the resistance decline histories such as flu or heating more;
2. conscious ophthalmalgia, photophobia, sheds tears, blurred vision;
3. cornea is from the beginning of point turbidity, then dendroid, map shape, discoid.
4. keratopathy district fluorescent staining is positive.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times, 6 months courses for the treatment of.
The oral levamisole of matched group, daily dose 200mg, one day 3 times, serve on 3 days, drug withdrawal 7 days.An outer 0.25% catilan collyrium, 6 months courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: clinical symptom disappearance; Examination with slitlamp microscope: corneal infiltration absorbs, corneal edema disappears, corneal ulcer reparation, and corneal scarring is formed; Fluorescein sodium is negative staining.
Effective: clinical symptom relief; Slit lamp examination: corneal infiltration basic absorption, corneal edema is not remarkable, and corneal ulcer is repaired substantially; Fluorescein sodium dyeing can be feminine gender, also can be the positive.As being positive, then color range should comparatively before reduce.
Invalid: clinical symptoms, lab testing is without improvement or increase the weight of.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment herpes simplex keratitis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: seven lis of pellets 0.6 gram, Herba Euphorbiae Helioscopiae 9 grams, Calculus Equi 3 grams, Fructus polygoni tinctorii 10 grams, Extract Querci semicarpifoliae Folium 2 grams, Radix fici panduratae 30 grams, Cortex Ailanthi 10 grams, Folium et Ramulus Callicarpae nudiflorae 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of herpes simplex keratitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: seven lis of pellets 0.6 gram, Herba Euphorbiae Helioscopiae 9 grams, Calculus Equi 3 grams, Fructus polygoni tinctorii 10 grams, Extract Querci semicarpifoliae Folium 2 grams, Radix fici panduratae 30 grams, Cortex Ailanthi 10 grams, Folium et Ramulus Callicarpae nudiflorae 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of herpes simplex keratitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: seven lis of pellets 0.6 gram, Herba Euphorbiae Helioscopiae 9 grams, Calculus Equi 3 grams, Fructus polygoni tinctorii 10 grams, Extract Querci semicarpifoliae Folium 2 grams, Radix fici panduratae 30 grams, Cortex Ailanthi 10 grams, Folium et Ramulus Callicarpae nudiflorae 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of herpes simplex keratitis.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of herpes simplex keratitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: seven lis of pellets 0.6 part, Herba Euphorbiae Helioscopiae 9 parts, Calculus Equi 3 parts, Fructus polygoni tinctorii 10 parts, Extract Querci semicarpifoliae Folium 2 parts, Radix fici panduratae 30 parts, Cortex Ailanthi 10 parts, Folium et Ramulus Callicarpae nudiflorae 12 parts.
2. a kind of Chinese medicine being used for the treatment of herpes simplex keratitis as claimed in claim 1, it is characterized in that, its preparation method is: take: seven lis of pellets 0.6 part, Herba Euphorbiae Helioscopiae 9 parts, Calculus Equi 3 parts, Fructus polygoni tinctorii 10 parts, Extract Querci semicarpifoliae Folium 2 parts, Radix fici panduratae 30 parts, Cortex Ailanthi 10 parts, Folium et Ramulus Callicarpae nudiflorae 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of herpes simplex keratitis as claimed in claim 1, it is characterized in that, its preparation method is: take: seven lis of pellets 0.6 part, Herba Euphorbiae Helioscopiae 9 parts, Calculus Equi 3 parts, Fructus polygoni tinctorii 10 parts, Extract Querci semicarpifoliae Folium 2 parts, Radix fici panduratae 30 parts, Cortex Ailanthi 10 parts, Folium et Ramulus Callicarpae nudiflorae 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of herpes simplex keratitis as claimed in claim 1, it is characterized in that, its preparation method is: take: seven lis of pellets 0.6 part, Herba Euphorbiae Helioscopiae 9 parts, Calculus Equi 3 parts, Fructus polygoni tinctorii 10 parts, Extract Querci semicarpifoliae Folium 2 parts, Radix fici panduratae 30 parts, Cortex Ailanthi 10 parts, Folium et Ramulus Callicarpae nudiflorae 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| CN201510527544.8A CN105168763A (en) | 2015-08-25 | 2015-08-25 | Traditional Chinese medicine treating herpes simplex keratitis |
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| CN201510527544.8A CN105168763A (en) | 2015-08-25 | 2015-08-25 | Traditional Chinese medicine treating herpes simplex keratitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106236958A (en) * | 2016-08-24 | 2016-12-21 | 王吉松 | A kind of Chinese medicine preparation treating viral keratitis |
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| CN1110597A (en) * | 1994-12-16 | 1995-10-25 | 赵志强 | Vision recovery capsule |
| CN1157155A (en) * | 1996-12-27 | 1997-08-20 | 王双 | Chinese patent drug for curing monovesicle viral keratitis |
| CN104288306A (en) * | 2014-09-17 | 2015-01-21 | 张道敬 | Traditional Chinese medicine eye drop for treating ocular diseases and preparation method thereof |
-
2015
- 2015-08-25 CN CN201510527544.8A patent/CN105168763A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1110597A (en) * | 1994-12-16 | 1995-10-25 | 赵志强 | Vision recovery capsule |
| CN1157155A (en) * | 1996-12-27 | 1997-08-20 | 王双 | Chinese patent drug for curing monovesicle viral keratitis |
| CN104288306A (en) * | 2014-09-17 | 2015-01-21 | 张道敬 | Traditional Chinese medicine eye drop for treating ocular diseases and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 陈建学等: "中西医结合治疗单疱病毒性角膜炎100例", 《甘肃中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106236958A (en) * | 2016-08-24 | 2016-12-21 | 王吉松 | A kind of Chinese medicine preparation treating viral keratitis |
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