CN105233181A - Medicine for treating gallstone - Google Patents
Medicine for treating gallstone Download PDFInfo
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- CN105233181A CN105233181A CN201510791587.7A CN201510791587A CN105233181A CN 105233181 A CN105233181 A CN 105233181A CN 201510791587 A CN201510791587 A CN 201510791587A CN 105233181 A CN105233181 A CN 105233181A
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Abstract
The invention relates to a medicine for treating gallstone. The medicine is prepared from the following raw medical materials in parts by weight: 15 parts of herba lysimachiae, 1 part of rabdosia lophanthide, 1 part of lawn pennywort herb, 8 parts of silybum marianum, 1 part of seed of field pennycress, 12 parts of mile swertia herb, 14 parts of sedum lineare and 8 parts of radix curcumae. According to the medicine, herba lysimachiae has the efficacies of eliminating dampness and heat, rabdosia lophanthide has the efficacies of cooling blood and dissipating blood stasis, lawn pennywort herb has the efficacies of dispelling wind and clearing heat, silybum marianum has the efficacies of protecting liver and gallbladder, field pennycress has the efficacies of inducing diuresis and reducing edema, mile swertia herb has the efficacies of clearing liver and protecting gallbladder, sedum lineare has the efficacies of clearing away heat and toxic materials, and radix curcumae has the efficacies of regulating vital energy and dispersing stagnation; by combining the raw materials, the medicine has the efficacies of soothing liver, protecting gallbladder, clearing heat and removing dampness and is capable of effectively treating the gallstone. A clinical experiment proves that the medicine can be used for safely and effectively treating the gallstone.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine being used for the treatment of cholelithiasis.
Background technology
Cholelithiasis is mainly seen in adult, and women is more than male, and within 40 years old, sequela rate increases with the age and increases.Calculus is cholesterol calculus or the mixed calculus based on cholesterol and black bile pigment calculus.
Cholelithiasis is relevant with many factors.Anyly affect cholesterol and bile acid concentration ratio changes and cause the factor of cholestasis to cause calculus.Indivedual area and ethnic resident, estrogen, obesity, gestation, high fat diet, long-term parenteral, diabetes, hyperlipemia, pacing stomach or the factor such as gastrointestinal anastomosis Post operation, terminal ileum disease and ileal resection is postoperative, liver cirrhosis, hemolytic anemia all can cause cholelithiasis.Relatively high at the cholelithiasis sickness rate in NORTHWEST CHINA area, may be relevant with dietary habit.
Main clinical manifestation is as 1. biliary colic: patient be everlasting heavy meal, feed greasy food after or sleep in Body Position Change time, cause angor.Pain is positioned at upper right abdomen or epigastrium, in paroxysmal, or the aggravation of constant pain paroxysmal, can radiate in scapular region and back to the right, can Nausea and vomiting be accompanied.2. upper abdomen dull pain 3. gallbladder hydrops: hydrops is transparent colourless, is also called white bile.
Current doctor trained in Western medicine clinical treatment cholelithiasis multiselect operative therapy, but mostly get rid of unclean, and drained life again, the basic reason that body calculus produces can not be removed, easily cause Relapse rate to show effect.
Medical material involved in the present invention is recorded in all as seen " China's book on Chinese herbal medicine ".
Herba Lysimachiae [source] this product is the dry herb of Ofthe Primulaceae Lysimachia christinae Hance LysimachiachristinaeHance.Summer, Qiu Erji gather, and removing impurity, dries.[nature and flavor] are sweet, salty, are slightly cold.[return through] returns liver, gallbladder, kidney, urinary bladder channel.[function cures mainly] eliminating damp-heat, treating stranguria, detumescence.For pyretic stranguria, Sha Lin, urinates and puckeryly to have a pain, jaundice dark coloured urine, carbuncle furuncle, venom; Liver and bile stone, lithangiuria.[usage and dosage] 15 ~ 60g; Fresh goods doubles.
Herba Rabdosiae Lophanthoidis [source] Labiatae Rabdosia plant Rabdosia lophanthoides Rabdosialophanthoides (Ham.exD.Don) Hara, herb.Xia Qiu gathers, and dries; Fresh goods can be adopted at any time.[nature and flavor] are bitter, cold.[function cures mainly] clearing away heat-damp and promoting diuresis, cool the blood dissipate blood stasis.For acute icterohepatitis, acute cholecystitis, enteritis, dysentery, treating swelling and pain by traumatic injury.[usage and dosage] 0.5 ~ 1 liang.
Herba Hydrocotyles [source] is samphire Herba Hydrocotyles HydrocotylesibthorpioidesLam. [H.rotundifoliaRoxb.], with all herbal medicine.The whole year can adopt, and using fresh herb or autumn gather and dry.[nature and flavor] are sweet, light, micro-pungent, cool.[function cures mainly] expelling wind and clearing away heat, preventing phlegm from forming and stopping coughing.For icteric infectious hepatitis, cirrhotic ascites, cholelithiasis, urinary system infection, urinary system calculus, Common Cold, cough, pertussis, pharyngolaryngitis, tonsillitis, corneal nebula; Eczema is controlled in external, herpes zoster, epistaxis.[usage and dosage] 3 ~ 5 money; Suitable amount used externally, fresh goods mashes deposited affected part.
Herba Silybi mariani [source] Compositae Silybum plant Herba Silybi mariani Silybummarianum (L.) Gaertn. [CarduusmarianusL.], is used as medicine with achene.Herba Silybi mariani is bloomed at the beginning of 7 months successively from first arrival in May, and head inflorescence is from blooming to ripe need of fruit 25 ~ 30 days, and be inwardly curled into cylinder when bract is withered and yellow, top pappus is when parting a little open, mark seed is ripe, should gather in time.With shears, infructescence is cut.[nature and flavor] are bitter, cool.[function cures mainly] heat-clearing and toxic substances removing, protects the liver, function of gallbladder promoting, protects brain, anti-X-ray.All there is good efficacy to liver, the scorching diseases of gallbladder such as inflammation around acute or chronic hepatitis, liver cirrhosis, fatty liver, metabolism toxic liver injury, cholelithiasis, cholangitis and hepatic duct, hepatopathy patient subjective symptoms and some biochemical index can be made as serum bilirubin, improvement rapidly such as white Anhui and ball Anhui coefficient, prothrombing, glutamate pyruvate transaminase etc.[usage and dosage] takes orally: decoct soup, 6-15g; Or make electuary, capsule, pill.
Herba Thlaspis [source] Cruciferae herba thlaspis genus plant Herba Thlaspis ThlaspiarvenseL., is used as medicine with herb and seed.Spring and summer gathers herb, dries; Autumn in summer fruit picking branch, dries, lays seed.[nature and flavor] herb: bitter, sweet, flat.Seed: pungent, bitter, tepor.[function cures mainly] herb: heat-clearing and toxic substances removing, inducing diuresis and reducing edema, and middle appetizing.For appendicitis, lung abscess, carbuncle furuncle and phyma poison, erysipelas, endometritis, leucorrhea, nephritis, cirrhotic ascites, infantile dyspepsia.Seed: expelling wind and removing dampness, and stomach and alleviating pain.For rheumatic arthritis, lumbago, acute conjunctivitis, stomachache, hepatitis.[usage and dosage] herb 0.3 ~ 1 liang, seed 3 ~ 4 money.
Herba Swertiae Mileensis [source] this product is gentianaceae plant Herba Swertiae Mileensis SwertiamileensisT.N.HeetW.L.Shi, dry herb.Autumn, flowering fruit bearing stage was gathered, and removing silt, dries.[nature and flavor] are bitter, sweet, cold.[return through] returns liver, gallbladder, urinary bladder channel.[function cures mainly] liver heat removing function of gallbladder promoting, clearing away heat-damp and promoting diuresis.For jaundice dark coloured urine, the puckery pain of pyretic stranguria.[usage and dosage] 10 ~ 15g.
Herba Sedi Linearis [source] medical material Ji Yuan: be the stem and leaf of crassulaceae plants Herba Sedi Linearis.[nature and flavor] are sweet; Light; Cold [return through] heart; Lung; Liver; Spleen channel [function cures mainly] heat-clearing and toxic substances removing; Dampness removing; Hemostasis.Main laryngopharynx swelling and pain; Conjunctival congestion toxic swelling; Pyretic toxicity carbuncle; Furuncle; Erysipelas; Herpes zoster; Burn and scald; Venom; Jaundice; Damp-heat dysentery; Have blood in stool; Metrorrhagia; Traumatic hemorrhage; Verruca plana [usage and dosage] external: appropriate, fresh goods is smash deposited; Or smash juice rinsing the mouth, eye dripping.For oral administration: to decoct soup, 9-15g, fresh goods 20-30g; Or smash juice.
Radix Curcumae [source] is zingiberaceous plant Rhizoma Curcumae Longae, the tuber of Radix Curcumae or Rhizoma Curcumae.Winter, spring excavate, and win tuber, and removing fibrous root, cleans earth, enter in boiling water to boil or steam to the saturating heart, takes out, dries.[nature and flavor] are pungent, bitter, cold.[return through] returns liver, the heart, lung meridian.[function cures mainly] regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.[usage and dosage] 3 ~ 9g.
Summary of the invention
The present invention aims to provide a kind of medicine being used for the treatment of cholelithiasis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing cholelithiasis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine being used for the treatment of cholelithiasis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Lysimachiae 15 parts, Herba Rabdosiae Lophanthoidis 1 part, Herba Hydrocotyles 1 part, Herba Silybi mariani 8 parts of, Herba Thlaspiss 1 part, Herba Swertiae Mileensis 12 parts, Herba Sedi Linearis 14 parts, Radix Curcumae 8 parts.
Inventor thinks: the liver failing to maintain the normal flow of QI, damp-heat accumulation.Impurity cannot excrete to deposit in gallbladder and form calculus, takes the method for depressed liver-energy dispersing and function of gallbladder promoting, clearing away heat and eliminating dampness during treatment.
The present invention uses: Herba Lysimachiae eliminating damp-heat; Herba Rabdosiae Lophanthoidis cool the blood dissipate blood stasis; Herba Hydrocotyles expelling wind and clearing away heat; Herba Silybi mariani hepatic cholagogic; Herba Thlaspis is inducing diuresis and reducing edema; Herba Swertiae Mileensis liver heat removing function of gallbladder promoting; Herba Sedi Linearis heat-clearing and toxic substances removing; Radix Curcumae regulating qi to disperse stagnation.All medicines share, and play effect of depressed liver-energy dispersing and function of gallbladder promoting, clearing away heat and eliminating dampness altogether, effectively treat cholelithiasis.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects gallstone patients 80 example for 2012 altogether between year December of December ~ 2014, all from hepatology outpatient service, and 30 ~ 54 years old age, male 35 example, women 45 example.The course of disease 1 ~ 4 year.
Diagnostic criteria: according to clinical typical angor medical history, imaging examination can be made a definite diagnosis.First-selected ultrasound diagnosis, has strong echo group, moves with Body Position Change, has sound shadow to be diagnosed as cholelithiasis thereafter in visible gallbladder.Only have the cholelithiasis of 10% ~ 15% to contain calcium, abdominal X-ray can be made a definite diagnosis, and position, side photo can be distinguished with right renal calculus.
Meet above-mentioned diagnostic criteria, the patient that the age is greater than 18 years old.
Exclusion standard: trimester of pregnancy, women breast-feeding their children; Merge serious cardiopulmonary hepatorenal disease person.
2, test method
The decoct that the oral the present invention of all patients obtains according to embodiment 1, every day 3 times.4 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
With reference to " new Chinese medicine guideline of clinical investigations "
1. cure: patient clinical symptoms, sign after treating 4 weeks disappear, and through ultrasound diagnosis display without calculus;
2. take a turn for the better: patient clinical symptoms, sign after treating 4 weeks make moderate progress, and reduce through ultrasound diagnosis display calculus;
3. invalid: patient clinical symptoms, sign after treating 4 weeks are comparatively treated front without improving, and ultrasound diagnosis display calculus is unchanged or increase.
3.2 therapeutic outcome
80 routine patients cure 54 examples, and take a turn for the better 21 examples, invalid 5 examples, total effective rate 93.7%.There is laxativeness in treatments period 2 example, has no other obvious adverse reaction.It is safe and effective that visible the present invention is used for the treatment of cholelithiasis, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Herba Lysimachiae 15 grams, Herba Rabdosiae Lophanthoidis 1 gram, Herba Hydrocotyles 1 gram, Herba Silybi mariani 8 grams of, Herba Thlaspiss 1 gram, Herba Swertiae Mileensis 12 grams, Herba Sedi Linearis 14 grams, Radix Curcumae 8 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of cholelithiasis.Oral, every bu morning, noon and afternoon take for three times.
Embodiment 2
Take: Herba Lysimachiae 15 grams, Herba Rabdosiae Lophanthoidis 1 gram, Herba Hydrocotyles 1 gram, Herba Silybi mariani 8 grams of, Herba Thlaspiss 1 gram, Herba Swertiae Mileensis 12 grams, Herba Sedi Linearis 14 grams, Radix Curcumae 8 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of cholelithiasis.Oral, daily once.
Embodiment 3
Take: Herba Lysimachiae 15 grams, Herba Rabdosiae Lophanthoidis 1 gram, Herba Hydrocotyles 1 gram, Herba Silybi mariani 8 grams of, Herba Thlaspiss 1 gram, Herba Swertiae Mileensis 12 grams, Herba Sedi Linearis 14 grams, Radix Curcumae 8 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of cholelithiasis.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of the medicine of cholelithiasis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Lysimachiae 15 parts, Herba Rabdosiae Lophanthoidis 1 part, Herba Hydrocotyles 1 part, Herba Silybi mariani 8 parts of, Herba Thlaspiss 1 part, Herba Swertiae Mileensis 12 parts, Herba Sedi Linearis 14 parts, Radix Curcumae 8 parts.
2. be used for the treatment of the medicine of cholelithiasis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Lysimachiae 15 parts, Herba Rabdosiae Lophanthoidis 1 part, Herba Hydrocotyles 1 part, Herba Silybi mariani 8 parts of, Herba Thlaspiss 1 part, Herba Swertiae Mileensis 12 parts, Herba Sedi Linearis 14 parts, Radix Curcumae 8 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the medicine of cholelithiasis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Lysimachiae 15 parts, Herba Rabdosiae Lophanthoidis 1 part, Herba Hydrocotyles 1 part, Herba Silybi mariani 8 parts of, Herba Thlaspiss 1 part, Herba Swertiae Mileensis 12 parts, Herba Sedi Linearis 14 parts, Radix Curcumae 8 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the medicine of cholelithiasis as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Lysimachiae 15 parts, Herba Rabdosiae Lophanthoidis 1 part, Herba Hydrocotyles 1 part, Herba Silybi mariani 8 parts of, Herba Thlaspiss 1 part, Herba Swertiae Mileensis 12 parts, Herba Sedi Linearis 14 parts, Radix Curcumae 8 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510791587.7A CN105233181A (en) | 2015-11-17 | 2015-11-17 | Medicine for treating gallstone |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510791587.7A CN105233181A (en) | 2015-11-17 | 2015-11-17 | Medicine for treating gallstone |
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| CN105233181A true CN105233181A (en) | 2016-01-13 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853582A (en) * | 2016-04-08 | 2016-08-17 | 广州暨南生物医药研究开发基地有限公司 | Folium artemisiae argyi containing medicine preparation for treating cholelithiasis and preparation method thereof |
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| CN101584754A (en) * | 2009-07-10 | 2009-11-25 | 于晓 | Medicinal preparation used for liver and gallbladder diseases and preparation method thereof |
| CN102078561A (en) * | 2009-12-01 | 2011-06-01 | 赵莉 | Chinese traditional medicine composition for treating gallstone |
| CN102743522A (en) * | 2012-07-27 | 2012-10-24 | 李振兴 | Traditional Chinese medicine stone-transforming powder |
| CN102949546A (en) * | 2012-10-29 | 2013-03-06 | 逄瑞莲 | Cholecystitis and gallstone treatment traditional Chinese medicine |
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2015
- 2015-11-17 CN CN201510791587.7A patent/CN105233181A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584754A (en) * | 2009-07-10 | 2009-11-25 | 于晓 | Medicinal preparation used for liver and gallbladder diseases and preparation method thereof |
| CN102078561A (en) * | 2009-12-01 | 2011-06-01 | 赵莉 | Chinese traditional medicine composition for treating gallstone |
| CN102743522A (en) * | 2012-07-27 | 2012-10-24 | 李振兴 | Traditional Chinese medicine stone-transforming powder |
| CN102949546A (en) * | 2012-10-29 | 2013-03-06 | 逄瑞莲 | Cholecystitis and gallstone treatment traditional Chinese medicine |
Non-Patent Citations (1)
| Title |
|---|
| 刘淑娟 等: ""以通为用"治疗胆囊炎的疗效观察与护理", 《青岛医药卫生》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853582A (en) * | 2016-04-08 | 2016-08-17 | 广州暨南生物医药研究开发基地有限公司 | Folium artemisiae argyi containing medicine preparation for treating cholelithiasis and preparation method thereof |
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Application publication date: 20160113 |