CN105435107A - Traditional Chinese medicine composition used for treating chronic pelvic inflammatory disease, and preparation method thereof - Google Patents

Traditional Chinese medicine composition used for treating chronic pelvic inflammatory disease, and preparation method thereof Download PDF

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CN105435107A
CN105435107A CN201510965859.0A CN201510965859A CN105435107A CN 105435107 A CN105435107 A CN 105435107A CN 201510965859 A CN201510965859 A CN 201510965859A CN 105435107 A CN105435107 A CN 105435107A
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Abstract

The invention discloses a traditional Chinese medicine composition used for treating chronic pelvic inflammatory disease. The traditional Chinese medicine composition is prepared from, by mass, 9 to 12 parts of spreading hedyotis herb, 6 to 9 parts of jasminum polyanthum Franch. flower, 4 to 8 parts of cryptotaenia joponica hassk., 3 to 11 parts of zelkova schneideriana bark, 7 to 12 parts of herb of ciliate Leucas, 4 to 9 parts of twelve stamen melastoma herb, 8 to 13 parts of folium perillae, 6 to 11 parts of herb of manystem stonecrop, 4 to 10 parts of rhizoma curcumae, 7 to 13 parts of scabrous doellingeria rhizome and root, 5 to 9 parts of cudrania cochin chinensis (Lour.) Kudo et masam., 3 to 8 parts of iresine herbstii Hook.f., and 6 to 10 parts of common goldenrod herb. The traditional Chinese medicine composition is prepared based on summarization of clinical practice of decades, and is capable of clearing heat and detoxifying, and promoting blood circulation to remove blood stasis; and curative effect is excellent.

Description

Be used for the treatment of Chinese medicine composition and the method for making of chronic pelvic inflammatory disease
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Chinese medicine composition and the method for making that are used for the treatment of chronic pelvic inflammatory disease.
Background technology
Pelvic inflammatory disease and pelvic inflammation refer to female pelvic cavity genitals, periuterine connective tissue and pelvic peritoneal inflammation.Chronic pelvic inflammation often acute stages treated is not thoroughly delayed, and its disease time is long, and the state of an illness is more obstinate.Antibacterial retrograde infection, by uterus, fallopian tube and arrive pelvic cavity.But in actual life, not all women can suffer from pelvic inflammatory disease, morbidity is minority just.This is because female reproductive system has natural defense function, under normal circumstances, the invasion of antibacterial can be resisted, only have the resistance when body to decline, or due to other reasons the natural defense function of women is destroyed time, just can cause the generation of pelvic inflammatory disease.Chronic pelvic inflammation: be due to acute pelvic inflammatory disease fail thoroughly treatment or patient's body constitution poor, caused by course of disease delay, the symptom of chronic pelvic inflammation is hypogastric region falling inflation, and pain and lumbosacral region are ached, and aggravate after fatigue of being everlasting, sexual intercourse and before and after menstruation.Next is irregular menstruation, irregular menses.When the course of disease is long can there is the neurasthenia symptom such as lassitude, whole body discomfort, insomnia in some women.Often prolongedly do not heal, recurrent exerbation, causes infertile, tubal pregnancy, has a strong impact on the health of women.
Publication No. CN103585467A(application number 201310590254.9) Chinese patent literature disclose a kind of medicament for the treatment of chronic pelvic inflammatory disease, it is made up of the material of following weight proportioning: blue pig ear, Cortex catalpae bungei, MANSHANXIANG, Radix Fici comatae, Flos Mume, Cissus pteroclada Hayata, Ilex purpurea Hassk.[I.chinensis Sims, Ramulus et Folium Bischofiae Javanicae, Parmelia tinctorum Despr., Herba hyperici attenuati, Herba Reineckeae Carneae, sanicle, Herba Lespedezae Cuneatae, Pleurospermum hookeri C.B.Clarde var.thomsonii C.B.Clarke, Cortex Xylosmae japonici, Rhizoma disporopsis pernyi, Lombardy poplar, clothing of failing, Caulis et Folium Hyptidis suaveolentis, Herba lychnidis coronatae, Herba hedyotis costatae and Rhizoma Tupistrae Chinensis.Publication No. CN104510812A(application number 201310464051.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of chronic pelvic inflammatory disease, be made up of by weight following Chinese medicinal components: Herba Leonuri 10-30 part, Herba hedyotis costatae 10-30 part, Radix Pulsatillae 10-30 part, flexuose bittercress herb and seed 10-30 part, Radix Clematidis Henryi 5-15 part, ear water Herba Amaranthi tricoloris 5-15 part, Radix Gentianae 5-15 part, Herba Patriniae 5-15 part.Publication No. CN104491540A(application number 201410792754.5) Chinese patent literature disclose a kind of Chinese medicine for the treatment of chronic pelvic inflammatory disease.The Chinese medicine of this treatment chronic pelvic inflammatory disease, is made up of the crude drug of following parts by weight: Herba Taraxaci 10-12g, Radix calophylli membranacei 7g, Radix Rubiae 8g, Radix Angelicae Sinensis 8g, Flos Eriocauli 5-10g, Flos Chrysanthemi 8g, Folium Pruni 3-10g, phyllanthus emblica 8g, Herba Eupatorii 8-10g, Herba Imperata cylindrica 6-10g, basyleaves 9g, rice bean 7-10g, freeze greenery 15g, Aspongopus 9g, Flos Inulae 8g, Fructus Akebiae 7g, Herba Cynomorii 7g, Actinolitum 7g, Fructus Corni 8g.
Drug therapy pelvic inflammatory disease is that primary and secondary effect is comparatively large mainly with Western medicine, and taking bad of rear patient should be serious, and therapeutic effect is very not remarkable, therefore needs to improve treatment means, strengthens the research to prescription face.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of curative effect reliable, take the safe Chinese medicine composition being used for the treatment of chronic pelvic inflammatory disease and method for making.
Technical scheme of the present invention is:
Be used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease, be prepared from primarily of following bulk drugs, be mass parts: Herba Hedyotidis Diffusae 9-12; Flos jasmini 6-9; Caulis et folium cryptotaeniae japonicae 4-8; Cortex zelkovae schneideriane 3-11; Herba leucadis ciliatae 7-12; Herba Melastomatis Dodecandri 4-9; Caulis Perillae 8-13; Herba Sedi Multicaulis 6-11; Rhizoma Curcumae 4-10; Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 7-13; Radix Cudraniae 5-9; Herba Iresines Herbstii 3-8; Herba Solidaginis 6-10.
Preferred version is, Herba Hedyotidis Diffusae 10-11; Flos jasmini 7-8; Caulis et folium cryptotaeniae japonicae 5-7; Cortex zelkovae schneideriane 5-9; Herba leucadis ciliatae 9-10; Herba Melastomatis Dodecandri 5-8; Caulis Perillae 10-11; Herba Sedi Multicaulis 7-10; Rhizoma Curcumae 6-8; Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 9-11; Radix Cudraniae 6-8; Herba Iresines Herbstii 4-7; Herba Solidaginis 7-9.
More preferably, Herba Hedyotidis Diffusae 10.5; Flos jasmini 7.5; Caulis et folium cryptotaeniae japonicae 6; Cortex zelkovae schneideriane 7; Herba leucadis ciliatae 9.5; Herba Melastomatis Dodecandri 6.5; Caulis Perillae 10.5; Herba Sedi Multicaulis 8.5; Rhizoma Curcumae 7; Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 10; Radix Cudraniae 7; Herba Iresines Herbstii 5.5; Herba Solidaginis 8.
The preparation method of the soft extract of described Chinese medicine composition, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) by clean to Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly, freeze-day with constant temperature, pulverizes, makes medicated powder together with step (1) (3) made crude drug, add the alcoholic solution of 65%, reflux, extract, 1-2 hour (preferred: reflux, extract, 1.3-1.7 hour; Be more preferably: reflux, extract, 1.5 hours), collecting by filtration filtrate decompression and solvent recovery;
(5) heat concentration step (4) gained filtrate to clear paste, add the simple syrup mixing of clear paste quality 0.4 times, stir, obtain soft extract.
The preparation method of described Chinese medicine composition soft extract, the consumption of the alcoholic solution of step (4) 65% by extraction medicated powder quality 7-10 doubly (preferred: the consumption of the alcoholic solution of 65% by 8-9 times of extractions medicated powder quality; Be more preferably: the consumption of the alcoholic solution of 65% by 8.5 times of extraction medicated powder quality).
The preparation method of the powder of described Chinese medicine composition, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, freeze-day with constant temperature, pulverizes and sieves, makes medicated powder, obtain powder together with step (1) (3) made crude drug.
The preparation method of described Chinese medicine powder, it is (preferred: to pulverize 200-240 mesh sieve that step (4) pulverized 180-260 mesh sieve; Be more preferably: pulverized 220 mesh sieves).
The preparation method of the honeyed pill of described Chinese medicine composition, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, be placed in marmite, add the water of boiled crude drug quality 6 times, decoct to boiling, lasting 14-26 minute (preferred: to continue 18-22 minute; Be more preferably: continue 20 minutes), collecting by filtration filtrate, filtering residue mixes with step (1) (3) made crude drug, adds water and again decocts, and after filtration, merges twice gained filtrate;
(5) spray drying step (4) gained filtrate, pulverizes dry thing, adds adjuvant refined honey water, generally makes ball, obtains honeyed pill.
The preparation method of described Chinese medicine composition pill, step (4) adds water and again decocts 10-22 minute (preferably: add water and again decoct 14-18 minute; Be more preferably: add water and again decoct 16 minutes).
The preparation method of the decoction of described Chinese medicine composition, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, be placed in marmite, decoct with water to boiling, change little fire and continue to decoct 16-26 minute (preferably: continue to decoct 18-24 minute; Be more preferably: continue decoction 21 minutes), collecting by filtration filtrate;
(5) step (1) (3) made crude drug was pulverized 80-160 mesh sieve (preferred: to pulverize fruit 100-140 mesh sieve; Be more preferably: pulverized 120 mesh sieves), make medicated powder, gained medicated powder is mixed with step (4) gained filtrate, be heated to boiling, filtered while hot, collect filtrate, obtain decoction.
The preparation method of described Chinese medicine composition decoction, the 8-10 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 8.5-9.5 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 9 times of boiled crude drug quality).
The Chinese medicine composition not only scientific formula being used for the treatment of chronic pelvic inflammatory disease provided by the invention, and preparation method is simple, product taking convenience.In addition, excellent results of the present invention also shows:
1, good effect of the present invention, anti-recurrence, untoward reaction is few, effectively can prevent recurrence;
2, this prescription meets Chinese medicine principle completely, has the effect such as heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling;
3, raw material of the present invention is Chinese medicinal plant material, and cheap and easy to get, cost is low, and long-term taking is without obvious toxic-side effects.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
Embodiment 1 is used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Hedyotidis Diffusae 9 parts, Flos jasmini 6 parts, Caulis et folium cryptotaeniae japonicae 4 parts, Cortex zelkovae schneideriane 3 parts, Herba leucadis ciliatae 7 parts, Herba Melastomatis Dodecandri 4 parts, Caulis Perillae 8 parts, Herba Sedi Multicaulis 6 parts, Rhizoma Curcumae 4 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 7 parts, Radix Cudraniae 5 parts, Herba Iresines Herbstii 3 parts, Herba Solidaginis 6 parts.The above-mentioned preparation method being used for the treatment of the Chinese medicine composition soft extract of chronic pelvic inflammatory disease is:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled and soak 7 minutes, take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, add washing water of rice rinse 18 minutes, take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, add yellow wine moistening 25 minutes, take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) by clean to Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly, freeze-day with constant temperature, pulverize together with step (1) (3) made crude drug, make medicated powder, add the alcoholic solution (consumption by 8.5 times of extraction medicated powder quality) of 65%, reflux, extract, 1.5 hours, collecting by filtration filtrate decompression and solvent recovery;
(5) heat concentration step (4) gained filtrate to clear paste, add the simple syrup mixing of clear paste quality 0.4 times, stir, obtain soft extract.
Embodiment 2 is used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Hedyotidis Diffusae 12 parts, Flos jasmini 9 parts, Caulis et folium cryptotaeniae japonicae 8 parts, Cortex zelkovae schneideriane 11 parts, Herba leucadis ciliatae 12 parts, Herba Melastomatis Dodecandri 9 parts, Caulis Perillae 13 parts, Herba Sedi Multicaulis 11 parts, Rhizoma Curcumae 10 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 13 parts, Radix Cudraniae 9 parts, Herba Iresines Herbstii 8 parts, Herba Solidaginis 10 parts.The preparation method being used for the treatment of the Chinese medicine powder of chronic pelvic inflammatory disease is:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled and soak 7 minutes, take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, add washing water of rice rinse 18 minutes, take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, add yellow wine moistening 25 minutes, take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, freeze-day with constant temperature, pulverized 220 mesh sieves, and made medicated powder, obtain powder together with step (1) (3) made crude drug.
Model case: xxx, female, 29 years old.Main suit: hypogastric region falling inflation, pain, companion leucorrhoea grow in quantity, foul smelling; Medical history: patient once must have vaginitis the year before, takes medicine rear remission, just discontinues medication afterwards, recently before and after each menstruation, hypogastric region distending pain, and with low grade fever, oral antibiotic, effect improved not obvious, the mental status is deteriorated gradually, and appetite declines, and to examination in hospital, is diagnosed as chronic pelvic inflammatory disease.
Take the Chinese medicine powder that the present embodiment gained is used for the treatment of chronic pelvic inflammatory disease, every day 2 times, each 3-5g, warm boiled water, 20 days courses for the treatment of.After patient takes a course for the treatment of, uncomfortable disease alleviates to some extent, and after continuing to take two courses for the treatment of, the eumenorrhea, leucorrhea quantity reduces, and the mental status is clearly better, check display, and inflammation is eliminated, and patient fully recovers.
Embodiment 3 is used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Hedyotidis Diffusae 10 parts, Flos jasmini 7 parts, Caulis et folium cryptotaeniae japonicae 5 parts, Cortex zelkovae schneideriane 5 parts, Herba leucadis ciliatae 9 parts, Herba Melastomatis Dodecandri 5 parts, Caulis Perillae 10 parts, Herba Sedi Multicaulis 7 parts, Rhizoma Curcumae 6 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 9 parts, Radix Cudraniae 6 parts, Herba Iresines Herbstii 4 parts, Herba Solidaginis 7 parts.The preparation method being used for the treatment of the Chinese medicine composition honeyed pill of chronic pelvic inflammatory disease is:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled and soak 7 minutes, take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, add washing water of rice rinse 18 minutes, take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, add yellow wine moistening 25 minutes, take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) by clean to Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly, be placed in marmite, add the water of boiled crude drug quality 6 times, decoct to boiling, continue 20 minutes, collecting by filtration filtrate, filtering residue mixes with step (1) (3) made crude drug, add water and again decoct 16 minutes, after filtration, merge twice gained filtrate;
(5) spray drying step (4) gained filtrate, pulverizes dry thing, adds adjuvant refined honey water, generally makes ball, obtains honeyed pill.
Model case: xxx, female, 36 years old.Medical history: patient is because excessively cleaning is lower cloudy, and cause menstruation irregularis, stomachache is serious, is diagnosed as chronic pelvic inflammatory disease on inspection, once took many medicines, the state of an illness does not take a turn for the better completely, occasionally has repeatedly, and existing symptom is whole body fatiguability, hypogastric region falling inflation, overworks or after sexual intercourse, pain increases the weight of.
Introduce through friend and take the Chinese medicine composition honeyed pill that the present embodiment gained is used for the treatment of chronic pelvic inflammatory disease, adopt every day 2 times, each 2-3 grain, with warm boiled water, 20 days courses for the treatment of.After patient takes a course for the treatment of, hypogastralgia is alleviated to some extent, and muscle power strengthens, adhere to taking three courses for the treatment of, menstruation is normal, and leucorrhea quantity reduces, and consolidates again a course for the treatment of, patient body is clearly better, check display, indices is all normal, without other uncomfortable diseases, follow up a case by regular visits in half a year, the state of an illness is without recurrence.
Embodiment 4 is used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Hedyotidis Diffusae 11 parts, Flos jasmini 8 parts, Caulis et folium cryptotaeniae japonicae 7 parts, Cortex zelkovae schneideriane 9 parts, Herba leucadis ciliatae 10 parts, Herba Melastomatis Dodecandri 8 parts, Caulis Perillae 11 parts, Herba Sedi Multicaulis 10 parts, Rhizoma Curcumae 8 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 11 parts, Radix Cudraniae 8 parts, Herba Iresines Herbstii 7 parts, Herba Solidaginis 9 parts.The preparation method being used for the treatment of the Chinese medicine composition decoction of chronic pelvic inflammatory disease is:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled and soak 7 minutes, take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, add washing water of rice rinse 18 minutes, take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, add yellow wine moistening 25 minutes, take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, be placed in marmite, the soak by water adding boiled crude drug quality 9 times, to boiling, changes little fire and continues decoction 21 minutes, collecting by filtration filtrate;
(5) step (1) (3) made crude drug was pulverized 120 mesh sieves, made medicated powder, gained medicated powder was mixed with step (4) gained filtrate, be heated to boiling, filtered while hot, and collected filtrate, obtain decoction.
Model case: xxx, female, 47 years old.Main suit: hypogastric region falling inflation and lumbosacral region are ached, with menorrhagia; Medical history: in nearly three months of patient, each moon is premenstrual, just occurs hypogastric region falling inflation, lumbosacral region is ached obviously, menstrual cycle increases, and increasing number, patient worries health, admission examination, find that uterus is rear position, limitation of activity, there is enclosed mass pelvic cavity side, during pressing, pain increases the weight of, and is diagnosed as chronic pelvic inflammatory disease.
Take the Chinese medicine composition decoction that the present embodiment gained is used for the treatment of chronic pelvic inflammatory disease, adopt every day 2 times, each 200-250ml, warmly to take, 20 days courses for the treatment of.After patient takes a course for the treatment of, uncomfortable disease obviously alleviates, pain relief, and after continuing to take two courses for the treatment of, patient menstrual's basic law, normal through measuring, check pelvic lump is eliminated, and consolidates a course for the treatment of, and patient fully recovers, and follows up a case by regular visits to half a year, without recurrence.
Embodiment 5 is used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease, is prepared from (every part of 10g) primarily of following bulk drugs: Herba Hedyotidis Diffusae 10.5 parts, Flos jasmini 7.5 parts, Caulis et folium cryptotaeniae japonicae 6 parts, Cortex zelkovae schneideriane 7 parts, Herba leucadis ciliatae 9.5 parts, Herba Melastomatis Dodecandri 6.5 parts, Caulis Perillae 10.5 parts, Herba Sedi Multicaulis 8.5 parts, Rhizoma Curcumae 7 parts, Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 10 parts, Radix Cudraniae 7 parts, Herba Iresines Herbstii 5.5 parts, Herba Solidaginis 8 parts.The preparation method being used for the treatment of the Chinese medicine composition soft extract of chronic pelvic inflammatory disease is:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled and soak 7 minutes, take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, add washing water of rice rinse 18 minutes, take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, add yellow wine moistening 25 minutes, take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) by clean to Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly, freeze-day with constant temperature, pulverize together with step (1) (3) made crude drug, make medicated powder, add the alcoholic solution (consumption by 8.5 times of extraction medicated powder quality) of 65%, reflux, extract, 1.5 hours, collecting by filtration filtrate decompression and solvent recovery;
(5) heat concentration step (4) gained filtrate to clear paste, add the simple syrup mixing of clear paste quality 0.4 times, stir, obtain soft extract.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Herba Hedyotidis Diffusae: base is former: be the herb of Rubiaceae plants of Hedyotis Herba Hedyotidis Diffusae.Xia Qiu gathers, and cleans, using fresh herb or dry.Nature and flavor: sweet, light, cool.Gui Jing: enter stomach, large intestine, small intestine meridian.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis), furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria; Furuncle carbuncle is controlled in external, venom.
Flos jasmini: base is former: be the dry flower of Oleaceae plants Flos jasmini.Nature and flavor: micro-hardship; Property is put down.Gui Jing: Liver Channel.Function cures mainly: soothing liver-QI for relieving depression; Promoting the circulation of QI to relieve pain.Side of body rib gastral cavity abdomen caused by main stagnation of QI due to depression of the liver is had a pain; Dysentery is suffered from abdominal pain.
Caulis et folium cryptotaeniae japonicae: base is former: be the stem and leaf of samphire Caulis et folium cryptotaeniae japonicae.Nature and flavor: acrid in the mouth; Bitter; Property is put down.Function cures mainly: dispelling wind stopping cough; Eliminating damp, detoxifying; Blood-activating analgetic.Main cold cough; Lung abscess; Drench pain; Hernia; Menoxenia; Acute toothache; Cataract; Carbuncle skin ulcer swells; Skin pruritus; Treating swelling and pain by traumatic injury; Snake bite and insect sting.
Cortex zelkovae schneideriane: base is former: be the bark of Ulmaceae beech tree.Nature and flavor: bitter; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Hemostasis; Diuretic; Antiabortive.Main cold, fever; Dysentery; Have blood in stool; Edema; Abdominal pain during pregnancy; Conjunctival congestion and swelling pain; Scald; Skin infection swells and ache.
Herba leucadis ciliatae: base is former: be the herb of labiate Herba leucadis ciliatae.Nature and flavor: bitter in the mouth; Pungent; Property is put down.Function cures mainly: dispersing liver and promoting blood circulation; Dispelling pathogenic wind for improving eyesight; Removing toxic substances.Housewife female's blood stasis amenorrhea; The pain over the hypochondriac region; Night blindness in children; Optic atrohic blindness cataracta; Swollen ulcer drug; Syphilis of the bone; Scabies; Erythra.
Herba Melastomatis Dodecandri: base is former: be the herb of Melastomateae plants Herba Melastomatis Dodecandri.Nature and flavor: sweet in the mouth; Puckery; Cool in nature.Gui Jing: GUIXIN; Liver; Spleen; Lung meridian.Function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation and hemostasis.Main high heat; Lung abscess; Pharyngeal swelling; Toothache; Dysentery; Jaundice; Edema; Dysmenorrhea; Metrorrhagia; Leukorrhagia; Puerperal abdonimal pain; Scrofula; Carbuncle; Furuncle; Hemorrhoid; Venom.
Caulis Perillae: base is former: be the stem of labiate wrinkle Folium Perillae, sharp Folium Perillae etc.Chemical analysis: Folium Perillae aerial parts is containing perilla ketone, and isoegomaketone, ergomaketon, Folium Perillae is right ethyl linolenate, linolenic acid and cupreol.Nature and flavor: acrid in the mouth; Warm in nature.Gui Jing: return spleen; Stomach; Lung meridian.Regulating the flow of QI to ease the stomach; Antiabortive; And blood.Main stagnation of QI in spleen and stomach; Gastral cavity abdomen feeling of fullness, nausea is got along well, edema beriberi, and spitting of blood tells nosebleed.
Herba Sedi Multicaulis: base is former: be stem and leaf or the root of crassulaceae plants gold stem Herba hylotelephii erythrosticti.Nature and flavor: sweet in the mouth; Micro-pungent; Cold nature.Gui Jing: lung; Kidney; Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Cooling blood for hemostasis; Wind-damp dispelling.Main laryngopharynx swelling and pain; Burst soup in oral cavity; Eczema sore; Epistaxis; Hemoptysis; Spitting of blood; Rheumatic arthralgia; Headache due to pathogenic wind-heat.
Rhizoma Curcumae: base is former: be the rhizome of zingiberaceous plant Rhizoma Curcumae.Chemical analysis: rhizome is containing volatile oil, and the composition contained in oil has Rhizoma Curcumae furanone, table Rhizoma Curcumae furanone, Rhizoma Curcumae furan hydrocarbon, curdione, curcumenol, Camphora, Borneolum Syntheticum etc.Nature and flavor: toil, temperature.Enter liver, spleen channel.Function cures mainly: removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, gather, women's blood stasis amenorrhea, traumatic injury is had a pain eating accumulation.
Rhizoma et Radix Doellingeriae (Herba Doellingeriae): base is former: be rhizome and the herb of feverfew Rhizoma et Radix Doellingeriae (Herba Doellingeriae) and Doellingeria marchandii (Levl) Ling..Nature and flavor: acrid in the mouth; Sweet; Property is micro-.Function cures mainly: heat-clearing and toxic substances removing; Improving eyesight; Sore-throat relieving.Main anemopyretic cold; Headache and dizziness; Conjunctival congestion and swelling pain; Pharyngitis; Acute kidney fire; Pneumonopathy is spitted blood; Traumatic injury; Carbuncle furuncle; Venom.
Radix Cudraniae: base is former: be the root of moraceae plants cudrania cochinchinensis or Zhe Shu.Nature and flavor: lightly seasoned; Micro-hardship; Cool in nature.Function cures mainly: dispelling wind and removing obstruction in the collateral; Removing damp-heat; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Traumatic injury; Yellow cellulitis; Parotitis; Pulmonary tuberculosis; Gastric duodenal ulcer; Stranguria with turbid discharge; Distention of the abdomen caused by various parasites; Amenorrhea; Impairment caused by overstrain hemoptysis; Treatment carbuncle sore swells.
Herba Iresines Herbstii: base is former: be the herb of amaranthaceous plant Iresine herbetii.Nature and flavor: sweet; Micro-hardship; Cool in nature.Gui Jing: liver; Large intestine channel.Function cures mainly: cooling blood for hemostasis; Clearing away heat-damp and promoting diuresis; Removing toxic substances.Main haematemesis; Epistaxis; Hemoptysis; Have blood in stool; Metrorrhagia; Dysentery; Have loose bowels; Damp-heat vaginal discharge; Carbuncle.
Herba Solidaginis: base is former: be herb or the root of Compositae Herba Solidaginis platymiscium Herba Solidaginis.Composition: aerial parts is containing saponin component: Herba Solidaginis glycosides, activities of Solidago virgaurea L saponin 3 that is 3, Solidago saponin, solidago canadesis saponin, huge Herba Solidaginis saponin, the triterpene glycosides etc. of Polygalacic acid.The property of medicine: pungent, bitter, cool.Function cures mainly: wind and heat dispersing, removing toxic substances and promoting subsidence of swelling.Cure mainly anemopyretic cold, laryngopharynx swelling and pain, cough due to lung-heat, jaundice, pyretic stranguria, carbuncle furuncle, venom, traumatic injury.Compatibility and incompatibility of drugs: " Guangdong Chinese medicine ": " can not decoct for a long time, decoct nauseating for a long time.”
Test example 1 gained of the present invention is used for the treatment of the clinical practice of the Chinese medicine composition (embodiment 5) of chronic pelvic inflammatory disease:
Choose crowd: in April ,-2015 in June, 2014, according to medical case history, screen undergoing chronic pelvic inflammation 258 example of accepting for medical treatment in four hospitals, age 20-48 year, 33.4 ± 1.8 years old mean age, the course of disease 3 months-2 years.All patients all defer to the principle of voluntariness, and meet chronic pelvic inflammatory disease diagnostic criteria (lumbosacral region is ached for 1. symptom: lower abdomen and lumbago, lower abdomen falling inflation, after fatigue of being everlasting, sexual intercourse, defecation time and menstruation before and after increase the weight of.Can increase and leucorrhoea grow in quantity with low grade fever, menstruation.2. gynecologial examination: Chang Chenghou position, uterus, limitation of activity or adhesion are fixed, and can touch streak thing, and have mild tenderness during salpingitis in face, one or both sides, uterus; During inflammation of pelvic connective tissue, one or both sides, uterus have lamellar to thicken, tenderness; Or lay one's hand on and enclosed mass in pelvic cavity one or both sides.）
Standards of grading: (1) uterine activity is limited, tenderness, 5 points; (2) fallopian tube is streak, tenderness, 5 points; (3) one or both sides, uterus have lamellar to thicken, tenderness, 5 points; (4) lower abdomen, waist are ached tenesmus, 3 points; (5) profuse leukorrhea, 1 point; (6) low grade fever, 1 point; (7) abdominal pain in menstruation, 1 point; (8) course of disease often increases by 1 year and adds, 0.5 point.
Before test, patient is divided into two groups at random, experimental group 150 example and matched group 108 routine, two groups in age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 6-8g, one day twice, warm boiled water, within 20 days, is a course for the treatment of; Matched group takes other conventional medicines (Pen Yan Jing pill, JINJI JIAONANG, fuyankang soft capsule etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: symptom, sign and inspection all recover normal, and integration is 0 point; (2) effective: transference cure, gynecologial examination has clear improvement, and reduces by more than 2/3 after treatment than integration before treatment; (3) effective: symptom, sign and check all to have and alleviate, than integration reduction by more than 1/3 before treatment after treatment; (4) invalid: without improving after treatment.
Clinical effectiveness: after the treatment of four courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
The total effective rate of experimental group is 97.3%, and the total effective rate of matched group is 88.9%, contrasts known, and the therapeutic effect of matched group is starkly lower than experimental group, illustrates that products obtained therefrom of the present invention is evident in efficacy, and therapeutic effect is good.Contrast the recurrence number of cases of two groups of patients, known products obtained therefrom of the present invention can effectively prevent the state of an illness from again recurring, treating both the principal and secondary aspects of a disease.
The Chinese medicine used in the present invention, the Herba Hedyotidis Diffusae of heat-clearing and toxic substances removing, Cortex zelkovae schneideriane, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), the Flos jasmini of soothing liver-QI for relieving depression, the Caulis et folium cryptotaeniae japonicae of blood-activating analgetic, the Herba leucadis ciliatae of dispersing liver and promoting blood circulation, the Herba Melastomatis Dodecandri of promoting blood circulation and hemostasis, the Caulis Perillae of regulating the flow of QI to ease the stomach, the Herba Sedi Multicaulis of cooling blood for hemostasis, the Rhizoma Curcumae of removing food stagnancy pain relieving, the Radix Cudraniae of removing damp-heat, Herba Iresines Herbstii, the Herba Solidaginis of removing toxic substances and promoting subsidence of swelling, multiple medical material synergism, plays effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. be used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Herba Hedyotidis Diffusae 9-12; Flos jasmini 6-9; Caulis et folium cryptotaeniae japonicae 4-8; Cortex zelkovae schneideriane 3-11; Herba leucadis ciliatae 7-12; Herba Melastomatis Dodecandri 4-9; Caulis Perillae 8-13; Herba Sedi Multicaulis 6-11; Rhizoma Curcumae 4-10; Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 7-13; Radix Cudraniae 5-9; Herba Iresines Herbstii 3-8; Herba Solidaginis 6-10.
2. be used for the treatment of the Chinese medicine composition of chronic pelvic inflammatory disease as claimed in claim 1, it is characterized in that, Herba Hedyotidis Diffusae 10-11; Flos jasmini 7-8; Caulis et folium cryptotaeniae japonicae 5-7; Cortex zelkovae schneideriane 5-9; Herba leucadis ciliatae 9-10; Herba Melastomatis Dodecandri 5-8; Caulis Perillae 10-11; Herba Sedi Multicaulis 7-10; Rhizoma Curcumae 6-8; Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 9-11; Radix Cudraniae 6-8; Herba Iresines Herbstii 4-7; Herba Solidaginis 7-9(is preferably: Herba Hedyotidis Diffusae 10.5; Flos jasmini 7.5; Caulis et folium cryptotaeniae japonicae 6; Cortex zelkovae schneideriane 7; Herba leucadis ciliatae 9.5; Herba Melastomatis Dodecandri 6.5; Caulis Perillae 10.5; Herba Sedi Multicaulis 8.5; Rhizoma Curcumae 7; Rhizoma et Radix Doellingeriae (Herba Doellingeriae) 10; Radix Cudraniae 7; Herba Iresines Herbstii 5.5; Herba Solidaginis 8).
3. the preparation method of the soft extract of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) by clean to Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly, freeze-day with constant temperature, pulverizes, makes medicated powder together with step (1) (3) made crude drug, add the alcoholic solution of 65%, reflux, extract, 1-2 hour (preferred: reflux, extract, 1.3-1.7 hour; Be more preferably: reflux, extract, 1.5 hours), collecting by filtration filtrate decompression and solvent recovery;
(5) heat concentration step (4) gained filtrate to clear paste, add the simple syrup mixing of clear paste quality 0.4 times, stir, obtain soft extract.
4. the preparation method of Chinese medicine composition soft extract as claimed in claim 3, it is characterized in that, the consumption of the alcoholic solution of step (4) 65% by extraction medicated powder quality 7-10 doubly (preferred: the consumption of the alcoholic solution of 65% by 8-9 times of extractions medicated powder quality; Be more preferably: the consumption of the alcoholic solution of 65% by 8.5 times of extraction medicated powder quality).
5. the preparation method of the powder of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, freeze-day with constant temperature, pulverizes and sieves, makes medicated powder, obtain powder together with step (1) (3) made crude drug.
6. the preparation method of Chinese medicine powder as claimed in claim 5, is characterized in that, it is (preferred: to pulverize 200-240 mesh sieve that step (4) pulverized 180-260 mesh sieve; Be more preferably: pulverized 220 mesh sieves).
7. the preparation method of the honeyed pill of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, be placed in marmite, add the water of boiled crude drug quality 6 times, decoct to boiling, lasting 14-26 minute (preferred: to continue 18-22 minute; Be more preferably: continue 20 minutes), collecting by filtration filtrate, filtering residue mixes with step (1) (3) made crude drug, adds water and again decocts, and after filtration, merges twice gained filtrate;
(5) spray drying step (4) gained filtrate, pulverizes dry thing, adds adjuvant refined honey water, generally makes ball, obtains honeyed pill.
8. the preparation method of Chinese medicine composition pill as claimed in claim 7, is characterized in that, step (4) adds water and again decocts 10-22 minute (preferably: add water and again decoct 14-18 minute; Be more preferably: add water and again decoct 16 minutes).
9. the preparation method of the decoction of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Flos jasmini and Caulis et folium cryptotaeniae japonicae cleans remove impurity, put into the vinegar liquid boiled soak 4-10 minute (preferred: to soak 6-8 minute; Be more preferably: soak 7 minutes), take out, be placed in parch container, moderate heat heats, and fries to surface in burnt brown, spray refined honey water, and go out most Mars, fried dry, and taking-up cools;
(2) get Cortex zelkovae schneideriane, Caulis Perillae and Rhizoma Curcumae and pick up clean impurity, it is (preferred: rinse 16-20 minute to add washing water of rice rinse 12-24 minute; Be more preferably: rinse 18 minutes), take out and be placed in steamer, Steam by water bath is saturating, and taking-up cools, and is cut into thread;
(3) Herba Sedi Multicaulis, Rhizoma et Radix Doellingeriae (Herba Doellingeriae), Radix Cudraniae and Herba Solidaginis are cleaned remove impurity, it is (preferred: moistening 22-28 minute to add yellow wine moistening 20-30 minute; Be more preferably: moistening 25 minutes), take out and cut sheet, be placed in parch container together with step (2) made crude drug, slow fire stir-fries to surface and turns yellow, and taking-up cools;
(4) Herba Hedyotidis Diffusae, Herba leucadis ciliatae, Herba Melastomatis Dodecandri and Herba Iresines Herbstii wash quickly is clean, be placed in marmite, decoct with water to boiling, change little fire and continue to decoct 16-26 minute (preferably: continue to decoct 18-24 minute; Be more preferably: continue decoction 21 minutes), collecting by filtration filtrate;
(5) step (1) (3) made crude drug was pulverized 80-160 mesh sieve (preferred: to pulverize fruit 100-140 mesh sieve; Be more preferably: pulverized 120 mesh sieves), make medicated powder, gained medicated powder is mixed with step (4) gained filtrate, be heated to boiling, filtered while hot, collect filtrate, obtain decoction.
10. the preparation method of Chinese medicine composition decoction as claimed in claim 9, is characterized in that, the 8-10 that step (4) amount of water is boiled crude drug quality is doubly (preferred: the 8.5-9.5 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 9 times of boiled crude drug quality).
CN201510965859.0A 2015-12-22 2015-12-22 Traditional Chinese medicine composition used for treating chronic pelvic inflammatory disease, and preparation method thereof Withdrawn CN105435107A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101167842A (en) * 2007-11-05 2008-04-30 贵阳春科药业技术研发有限公司 Medicinal preparation for treating gynecologic inflammation and hysteromyoma and its preparation method
CN102949672A (en) * 2012-11-27 2013-03-06 薄天宇 Medicine for treating pelvic inflammation
CN104474473A (en) * 2014-12-04 2015-04-01 吴瑞岚 Traditional Chinese medicine composition for treating gynecologic inflammation and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101167842A (en) * 2007-11-05 2008-04-30 贵阳春科药业技术研发有限公司 Medicinal preparation for treating gynecologic inflammation and hysteromyoma and its preparation method
CN102949672A (en) * 2012-11-27 2013-03-06 薄天宇 Medicine for treating pelvic inflammation
CN104474473A (en) * 2014-12-04 2015-04-01 吴瑞岚 Traditional Chinese medicine composition for treating gynecologic inflammation and preparation method thereof

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