CN105535077A - Traditional Chinese medicine for treating myocardial infarction - Google Patents
Traditional Chinese medicine for treating myocardial infarction Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention relates to a traditional Chinese medicine for treating myocardial infarction. The traditional Chinese medicine is prepared from, by weight, 12 parts of Sabina squamata, 4.5 parts of actinolite, 12 parts of Ludwigia repens, 15 parts of Nanocnide japonica Bl., 15 parts of Lampranthus, 9 parts of daghestan sweet clover herb, 9 parts of viburnum cylindricum, 12 parts of wedelia chinensis and 9 parts of primula obconica hance. A clinic experiment proves that the traditional Chinese medicine can safely and effectively treat myocardial infarction.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of myocardial infarction.
Background technology
Myocardial infarction refers to coronary occlusion, and the cardiac muscle of corresponding site is necrosed because of severe ischemic.There are violent and lasting retrosternal pain, heating, leukocytosis, erythrocyte sedimentation rate quickening, serum cardiac enzyme activity to increase and Progressive symmetric erythrokeratodermia ECG Change clinically, arrhythmia, shock or heart failure can occur.The patient of 60%-80% with or have hypertension at premorbid, nearly half patient had angina pectoris in the past.Smoking, obesity, diabetes and lack physical exertion person, more ill.Primary disease and very cold, temperature Change are relevant.Peace and quiet of being everlasting are fallen ill with during sleep, and some patients then falls ill after intense physical work, psychentonia or heavy meal, in addition.Shock, hemorrhagely defecate also can bring out primary disease with tachycardia, firmly.
Basic disease cause is coronary atherosclerosis (even caused by coronary thrombosis, spasm, inflammation, congenital malformation), causes luminal stenosis.Once atheromatous plaque increase, Rupture haemorrhag, thrombosis or fixed spasm, tube chamber is entirely shut, can myocardial infarction be caused.Secondly the general anterior descending branch the most often involving left coronary artery is the Circumflex branch of right coronary artery and left coronary artery.Left anterior descending obturation causes front 2/3 infarction in left ventricle antetheca, the apex of the heart and ventricular septum; After left Circumflex branch obturation, infarction betides left ventricular lateral wall, or involves rear portion, interval after left ventricle; Right coronary artery occlusion then causes 1/3 district's infarction behind right ventricle's front side wall, right ventricle's rear wall, LVPW and ventricular septum.Right ventricle blood for main from right coronary artery, but because of right ventricle workload little, locular wall is thinner, therefore its blood is made up in ventricular chamber for more direct, and therefore simple Right Ventricular Infarction is few.
Medical material present Research involved in the present invention is as follows:
High mountain cypress [another name] mountain cypress.[source] medical material Ji Yuan: be branch and leaf or the cone of Cupressaceae plant high mountain cypress.Gather and store: the 8-9 month adopts branch, leaf, dries; October adopts cone, or it is for subsequent use to endure cream.[nature and flavor] bitter in the mouth; Property is put down.[return through] returns kidney channel, urinary bladder channel.[function cures mainly] expelling wind and removing dampness; Removing toxic substances and promoting subsidence of swelling.Main air pain of dampness syndrome; Oedema due to nephritis; Urinary tract infection; Carbuncle pyogenic infections from tumour or sore.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Actinolitum [another name] Bai Shi, Shi Sheng.The Ore that [source] is silicates mineral Actinolitum or actinolite asbestos.Adopt after, remove earth, assorted stone.[nature and flavor] are salty, temperature.[return through] enters kidney channel.[function cures mainly] warming and recuperating the gate of life.Control the inferior burnt deficiency and coldness, the cold numbness of waist knee joint, impotence in male, woman's cold womb, lump in the abdomen metrorrhagia.[usage and dosage] takes orally: decoct soup, 3 ~ 4.5g.[attention] hyperactivity of fire caused by deficiency of YIN person avoids it.Sexual impotence belongs to mental confusion, so that fire of moxibustion closes close must not sending out more and so, and metrorrhagia leukorrhagia is contained but not deficiency and coldness person due to fire, and must not take.[extracts] " China's book on Chinese herbal medicine ".
Radix Phyllagathis fordii [another name] Radix Euonymi japonici, YEXIAHONG, Begonia aptera Bl., Huechys sanguinea De Geer., south of the River Begonia aptera Bl., Pericarpium Arecae Serpentis, blood are revived after death, it is red to revive after death, sand avalanche is careless, false Folium Perillae, red back of the body Begonia aptera Bl..[source] medical material Ji Yuan: be the Herb of Herba Melastomatis Candii Radix Phyllagathis fordii.Gather and store: summer, autumn gather, using fresh herb or dry.[nature and flavor] mildly bitter flavor; Sweet; Cool in nature.[return through] returns liver; The heart; Urinary bladder channel.[function cures mainly] nourishing blood for regulating menstruation.Main blood deficiency and yellow complexion; Menoxenia; Amenorrhea; Dysmenorrhea; Leukorrhagia.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
The high pier grass of Herba Nanocnides Japonicae [another name], Japan flower point grass, little Herba Polygoni Runcinati.[source] medical material Ji Yuan: be the herb of contrayerva flower point grass.Medical material Ji Yuan: be the herb of contrayerva flower point grass.[nature and flavor] are light; Cool in nature.[function cures mainly] heat-clearing and toxic substances removing; Cough-relieving; Hemostasis.Main jaundice; Pulmonary tuberculosis hemoptysis; Hectic fever; Hemorrhoid; Miliaria.[usage and dosage] takes orally: decoct soup, 30 ~ 60g.[extracts] " China's book on Chinese herbal medicine ".
Japan and China spend [another name] Herba Hylothelephii Verticillati, the period of the day from 11 a.m. to 1 p.m is careless, mouth is careless, ricebird tongue.[source] medical material Ji Yuan: be the herb of portulacaceous plant shaggy portulaca.Gather and store: summer, Qiu Erji gather, removing very residual and impurity, cleaning, drying after slightly steaming or scalding.[nature and flavor] are sweet; Cold nature.[function cures mainly] clearing away heat-damp and promoting diuresis; Removing toxic substances.Main hygropyretic dysentery; Furuncle.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Herba Meliloti Suaveolentis [another name] Herba medicaginis falcatae, Kochia scoparia, Herba boeae clarkeanae, Ocimum basilicum L. var. pilosum, wild peanut, Caput Gallus domesticus flowers and plants, chicken lousewort, Herba Meliloti officinalis, smelly Herba Medicaginis, the grass that relieves internal heat, fragrant horse material, Rhizoma aspidistrae luridae grass.[source] is the herb of leguminous plant melilotus.Gather and store: 6-8 extracts aerial parts the florescence month, using fresh herb or dry, cutting is for subsequent use.[nature and flavor] are pungent; Sweet; Micro-hardship; Cool in nature; [return through] liver; Spleen; Stomach warp.[function cures mainly] clearing away summer-heat and eliminating dampness; Stomach invigorating and in.Main heat-damp in summer breast is vexed; Feeling of fullness in the head is had a headache; Dysentery; Malaria; Stranguria; Leukorrhagia; Aphtha; Halitosis; Skin infection; Eczema; Scabies; Lymphoid tuberculosis.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] taste the person of trembling with fear be cautious use of, and anemia of pregnant woman is forbidden.[extracts] " China's book on Chinese herbal medicine ".
Rub Bai Ye [another name] powder Folium paulowniae, sheep gristle, sleep fruit, Canis familiaris L. rib bar.[source] Caprifoliaceae Viburnum vegetation water redwood, is used as medicine with root, leaf, flower.Root, leaf can be adopted the whole year, dry; Hua Xiaqiu gathers.[nature and flavor] are bitter, cool.[return through] returns kidney channel, stomach through, urinary bladder channel.[function cures mainly] leaf: heat-clearing and toxic substances removing.For dysentery, acute gastroenteritis, stomatitis, urinary tract infection; Burn and scald is controlled in external, sore swollen toxin, skin pruritus.Root: dispelling, collateral-activating.For traumatic injury, rheumatism bones and muscles pain.Flower: nourishing the lung to arrest cough.For xeropulmonary cough.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Herbia Wedeliae [another name] Flos Chrysanthemi Indici, Herba Kalimeridis grass, Sesarmae dehaani is colored, water is blue, Herba Wedeliae Prostratae, Hemerocallis citrina Baroni Herba Otteliae Alismoidis, Hemerocallis citrina Baroni Anacamptis pyromaidalis, liatris, Hemerocallis citrina Baroni ink dish, Herba Otteliae Alismoidis.[source] medical material Ji Yuan: be the herb of feverfew Herbia Wedeliae.Gather and store: herb of gathering in spring, summer, autumn uproots, and using fresh herb or cutting are dried.[nature and flavor] mildly bitter flavor; Sweet; Cool in nature.[function cures mainly] heat-clearing and toxic substances removing; Cool the blood dissipate blood stasis.Main cold, fever; Pharyngolaryngitis; Tonsillitis; Rib adenitis; Diphtheria; Pertussis; Tracheitis; Pneumonia; Hemoptysis of pulmonary tuberculosis; Epistaxis; Hematuria; Infectious hepatitis; Dysentery; Hemorrhoid; Furuncle insane asylum toxic swelling.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Primula obconica Hance. [another name] Radix Bischofiae Javanicae [Hubei, Lichuan], Primula obconica.[source] medical material Ji Yuan: be the root of Ofthe Primulaceae Primula obconica Hance..Gather and store: autumn or the early spring dig, removing aerial parts, cleans, dries.[nature and flavor] are bitter; Cool in nature.[return through] spleen, stomach two warp.[function cures mainly] alcoholic intoxication; Only stomachache.Master is addicted to drink immoderate; The alcoholism impairment of the spleen; Stomachache is just let out.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of myocardial infarction, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing myocardial infarction.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of myocardial infarction, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: high mountain cypress 12 parts, Actinolitum 4.5 parts, Radix Phyllagathis fordii 12 parts, Herba Nanocnides Japonicae 15 parts, Japan and China spend 15 parts, Herba Meliloti Suaveolentis 9 parts, rub Bai Ye 9 parts, Herbia Wedeliae 12 parts, Primula obconica Hance. 9 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects outpatient service and myocardial infarction patient 96 example of being in hospital altogether between 2012 09 month ~ 2013 09 month, be divided into treatment group 48 example and matched group 48 example at random, treatment group man 29 example, female 19 example, 48.4 years old mean age; Matched group man 31 example, female 17 example, 53.5 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national myocardial infarction clinical speciality:
Have acutely and comparatively lasting retrosternal pain clinically, heating, leukocytosis, erythrocyte sedimentation rate are accelerated, and serum cardiac enzyme activity increases and Progressive symmetric erythrokeratodermia ECG Change, and arrhythmia, shock or heart failure can occur.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.8 weeks courses for the treatment of.
The oral metoprolol tartrate extended release tablets of matched group, 50mg/ time, 2 times/d.8 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: 1. clinical symptoms disappears substantially; 2. limbs wound surface heals completely; 3. distal limb disturbance of blood circulation and rheography obviously change; 4. walking speed 100 ~ 120 steps/rain, can continue walking and be about about 1000m;
Effective: 1. clinical symptoms is obviously improved; 2. limbs wound healing or close healing: 3. distal limb disturbance of blood circulation and rheography are all improved: 4. walking speed 100 ~ 120 steps/min.Walking about 500m can be continued.
Effective: 1. clinical symptom relief; 2. limbs wound surface is close to healing or reducing; 3. distal limb disturbance of blood circulation and rheography are all improved; 4. walking speed 100 ~ 120 steps/min. can continue walking about 300m.
Invalid: after treating 1 course for the treatment of, symptom and sign continue development person without improvement or the state of an illness.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment myocardial infarction, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: high mountain cypress 12 grams, Actinolitum 4.5 grams, Radix Phyllagathis fordii 12 grams, Herba Nanocnides Japonicae 15 grams, Japan and China spend 15 grams, Herba Meliloti Suaveolentis 9 grams, rub Bai Ye 9 grams, Herbia Wedeliae 12 grams, Primula obconica Hance. 9 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of myocardial infarction.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: high mountain cypress 12 grams, Actinolitum 4.5 grams, Radix Phyllagathis fordii 12 grams, Herba Nanocnides Japonicae 15 grams, Japan and China spend 15 grams, Herba Meliloti Suaveolentis 9 grams, rub Bai Ye 9 grams, Herbia Wedeliae 12 grams, Primula obconica Hance. 9 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of myocardial infarction.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: high mountain cypress 12 grams, Actinolitum 4.5 grams, Radix Phyllagathis fordii 12 grams, Herba Nanocnides Japonicae 15 grams, Japan and China spend 15 grams, Herba Meliloti Suaveolentis 9 grams, rub Bai Ye 9 grams, Herbia Wedeliae 12 grams, Primula obconica Hance. 9 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of myocardial infarction.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of myocardial infarction, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: high mountain cypress 12 parts, Actinolitum 4.5 parts, Radix Phyllagathis fordii 12 parts, Herba Nanocnides Japonicae 15 parts, Japan and China spend 15 parts, Herba Meliloti Suaveolentis 9 parts, rub Bai Ye 9 parts, Herbia Wedeliae 12 parts, Primula obconica Hance. 9 parts.
2. be used for the treatment of the Chinese medicine of myocardial infarction as claimed in claim 1, it is characterized in that, its preparation method is: take: high mountain cypress 12 parts, Actinolitum 4.5 parts, Radix Phyllagathis fordii 12 parts, Herba Nanocnides Japonicae 15 parts, Japan and China spend 15 parts, Herba Meliloti Suaveolentis 9 parts, rub Bai Ye 9 parts, Herbia Wedeliae 12 parts, Primula obconica Hance. 9 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of myocardial infarction as claimed in claim 1, it is characterized in that, its preparation method is: take: high mountain cypress 12 parts, Actinolitum 4.5 parts, Radix Phyllagathis fordii 12 parts, Herba Nanocnides Japonicae 15 parts, Japan and China spend 15 parts, Herba Meliloti Suaveolentis 9 parts, rub Bai Ye 9 parts, Herbia Wedeliae 12 parts, Primula obconica Hance. 9 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of myocardial infarction as claimed in claim 1, it is characterized in that, its preparation method is: take: high mountain cypress 12 parts, Actinolitum 4.5 parts, Radix Phyllagathis fordii 12 parts, Herba Nanocnides Japonicae 15 parts, Japan and China spend 15 parts, Herba Meliloti Suaveolentis 9 parts, rub Bai Ye 9 parts, Herbia Wedeliae 12 parts, Primula obconica Hance. 9 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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CN104983884A (en) * | 2015-07-26 | 2015-10-21 | 黄萍 | Traditional Chinese medicine composition for treating arteriosclerosis obliterans caused by excessive noxious heat |
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Application publication date: 20160504 |