CN104998078A - Traditional Chinese medicine for treating infectious endocarditis - Google Patents
Traditional Chinese medicine for treating infectious endocarditis Download PDFInfo
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- CN104998078A CN104998078A CN201510514964.2A CN201510514964A CN104998078A CN 104998078 A CN104998078 A CN 104998078A CN 201510514964 A CN201510514964 A CN 201510514964A CN 104998078 A CN104998078 A CN 104998078A
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Abstract
The invention relates to a traditional Chinese medicine for treating infectious endocarditis. The traditional Chinese medicine is prepared from the following active pharmaceutical ingredients by weight: 20 parts of ludwigia octovalvis, 12 parts of fir seed, 15 parts of lactuca indica, 8 parts of small scouring rush, 15 parts of herb of Chinese arundina, 20 parts of stellaria dichotoma, 30 parts of emblic leafflower fruit and 9 parts of wild achyranthes bidentata. Clinical trials prove that the traditional Chinese medicine can be utilized for safely and effectively treating infectious endocarditis.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of infective endocarditis.
Background technology
Infective endocarditis, refer to produce because of antibacterial, fungus and other microorganism (as Coxsackie virus, rickettsia etc.) direct infection endocardium, cardiac valve acute, subacute inflammation pathological changes.Clinical in heating, cardiac murmur, embolization, blood culture with positive bacteria etc. are feature.Primary disease is more common in natural endowment deficiency, or weakness due to chronic disease, or eating and drinking without temperance, or excess of sexual intercourse, or disorder of emotion, and the cloudy essence of wasting QI-blood, cause positive QI-insufficiency, weakened defensive QI, warm malicious heresy is taken advantage of a weak point.Or through defending biography QI and blood, from outward appearance to inner essence; Also can direct attack edema caused by disorder of QI, or through nutrient blood, the battalion of heat is cloudy, the absurd row of forcing blood, even the pathogen attacking the pericardium adversely, becomes raw danger card.Sick to the later stage, to the greatest extent, cloudy liquid is hindered, and pathogenic heat is loved and divided in the moon, or deficiency of YIN blood is puckery, stops in blood stasis, or the disturbance of deficiency-heat inside the body mind, damp and hot heresy at remaining evil end, and consumption impairment of QI is cloudy, and deficiency of both QI and YIN, insufficiency of vital energy and blood, the heart is become homeless foster, then all cards are grown thickly.Heart governing blood and vessels, healthy energy virtual loss, gives up in the nutrient blood of heart arteries and veins in warm evil poison, then can cause skin visceral hemorrhage; Warm evil poison decocts nutrient blood, and warm blood is tied mutually, checks blood vessels, then can hyperamization arteries and veins thromboembolism is all levies.
Medical material present Research involved in the present invention is as follows:
Dendrobium nobile Lindl, key cylinder, Herba Jussiaeae suffruticosae, syringe grass, water seedling grass, water lamp perfume, water Fructus Musae in Ludwigia octovalvis (Jacq.) Raven [another name] grass, sweep pot grass, grass dragon, false yellow car, false any of several broadleaf plants.[source] medical material Ji Yuan: be the herb of onagraceae plant Herba Ludwigiae Prostratae.Gather and store: aerial parts of gathering in summer, autumn, cleaning, using fresh herb or dry.[nature and flavor] bitter in the mouth; Micro-pungent; Cold in nature.[return through] [function cures mainly] clearing away heat-damp and promoting diuresis; Removing toxic substances and promoting subsidence of swelling.Main cold, fever; Children's's infantile malnutrition with fever; Laryngopharynx swelling and pain; Aphtha of the mouth and tongue; Hypertension; Edema; Damp-heat dysentery; Drench pain; Nebulousurine; Leukorrhagia; Acute mastitis; Furuncle swelling toxin; Hemorrhoid; Burn and scald; Venom.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Semen Abietis Delavayi [another name] Tang Ze, tower China fir.[source] medical material Ji Yuan: be the seed of pinaceae plant Abies delavayi.Gather and store: autumn plucks when cone is closely ripe, lays scale and seed gently, then sifts out seed, life is used or stir-fry is used.[nature and flavor] are pungent; Warm in nature.Regulate the flow of vital energy during [function cures mainly] is wet; Dispersing cold for relieving pain.Main sun stroke pain due to disorder of QI; Gastral cavity abdomen; Cold type of pain, colicky.[usage and dosage] takes orally: decoct soup, 9 ~ 12g.[extracts] " China's book on Chinese herbal medicine ".
The young grass of straw sandals green grass or young crops [another name] goose, Flos Inulae.[source] medical material Ji Yuan: be the herb of Thelypteridaceae plant Pronephrium simplex.Gather and store: the whole year all can gather, drying or using fresh herb.[nature and flavor] are bitter; Micro-puckery; Cool.[return through] returns spleen, stomach, kidney three warp.[function cures mainly] heat-clearing and toxic substances removing.Main laryngopharynx swelling and pain; Dysentery; Venom [usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Equisetum pratense [another name] horse beard.[source] medical material Ji Yuan: for Equisetaceae plant plait asks the herb of type.Gather and store: summer excavates, cleaning, dry or using fresh herb.[nature and flavor] bitter in the mouth; Property is put down.[function cures mainly] invigorates blood circulation; Diuresis; Anthelmintic.Atherosclerosis of aorta; Difficulty and pain in micturition is unfavorable; Intestinal parasitical diseases.[usage and dosage] takes orally: decoct soup, 5-10g, fresh goods 30-60g.[extracts] " China's book on Chinese herbal medicine ".
Herba Arundinae Chinensis [another name] great Ye Radix Cynanchi Paniculati, careless Rhizoma Zingiberis Recens, mountain Corm Eleocharitis.[source] medical material Ji Yuan: be herb and the root stock of orchid Herba Murdanniae Divergentis.Gather and store: the whole year all can adopt, clean, using fresh herb or section are dried.[nature and flavor] are bitter; Be slightly cold, [return through] liver; Kidney; Urinary bladder channel, [function cures mainly] heat-clearing and toxic substances removing; Expelling wind and removing dampness.Main pyretic stranguria; Jaundice; Edema; Beriberi edema; Hernia is suffered from abdominal pain; Rheumatic arthralgia; Venom; Sore and toxic; Traumatic injury, [usage and dosage] are taken orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Herba Stellariae dichotomae [another name] Fructus Choerospondiatis core, mountain Ziziphi Spinosae.[source] Caryophyllaceae Herba Stellariae dichotomae is with root, all herbal medicine.[nature and flavor] are sweet, are slightly cold.[return through] enters liver, kidney, pericardium channel.[function cures mainly] tonifying liver, mind calming, arresting sweating, promotes the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty, night sweat hectic fever due to YIN-deficiency.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[attention] all livers, gallbladder, spleen three through there being the hot person of excess pathogen not use, with its convergence thus also.[extracts] " China's book on Chinese herbal medicine ".
Emblic leafflower fruit [another name] Fructus Phyllanthi, emblic, Buddhist nunnery rub character used in proper names and in rendering some foreign names fruit, hope fruit, Phyllanthus embical fruit, Niu Ganzi, olive pull son, pyhllanth usemhlica L., barna really, Yunnan Fructus Canarii albi.[source] is the fruit of euphorbia plant phyllanthus emblica.9 ~ October gathers when fruit is ripe, dries.[nature and flavor] are bitter sweet, cold.[return through] enters spleen, stomach two warp.[function cures mainly] reduces phlegm, and promotes the production of body fluid, cough-relieving, removing toxic substances.Cure cold heating, cough pharyngalgia, diphtheria, restlessness and fever with thirst.[usage and dosage] takes orally: decoct soup, 10 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Radix Achyranthis Bidentatae [another name] Radix Achyranthis Bidentatae, cattle condyle knee joint, Herba Ophiorrhizae pumilae, Twotooth Achyranthes Root, Red Radix Achyranthis Bidentatae, Du's Radix Achyranthis Bidentatae, Radix Achyranthis.[source] this product is the dry root of amaranthaceous plant Radix Achyranthis Bidentatae.Excavate when winter, stem and leaf was withered, removing fibrous root and silt, be bundled into wisp, shine to shriveling, trimmed on top, dry.[nature and flavor] are bitter, sour, flat.[return through] returns liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, eliminating blood stasis and inducing menstruation, conducting blood to flow downwards.For soreness of waist and knee joint, muscles and bones is unable, amenorrhea lump in the abdomen, dizziness due to hyperactivity of liver-YANG.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] anemia of pregnant woman is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of infective endocarditis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing infective endocarditis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of infective endocarditis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: blue or green 15 parts of Ludwigia octovalvis (Jacq.) Raven 20 parts, Semen Abietis Delavayi 12 parts, straw sandals, Equisetum pratense 8 parts, Herba Arundinae Chinensis 15 parts, Herba Stellariae dichotomae 20 parts, emblic leafflower fruit 30 parts, Radix Achyranthis Bidentatae 9 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor in October, 2012 ~ 2013 collect outpatient service and HOI endocarditis patient 60 example altogether between year October, be divided into treatment group 30 example and matched group 30 example at random, treatment group man 10 example, female 20 example, 41.5 years old mean age; Matched group man 12 example, female 18 example, 39.5 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national infective endocarditis clinical speciality:
(1), original chronic valvulopathy or congenital heart disease, wherein especially with Bicuspid valve, the light moderate regurgitation of aortic valve, little ventricular septal defect and patent ductus arteriosus person common.Minority case premorbid heart is without exception.Premorbid often has operation, instrumental examination or infects history.
(2), irregular moderate heating, minority low grade fever or intermittent fever, companion fear of cold, loss of appetite, lose weight, muscular soreness, anemia, splenomegaly, there is drumstick finger, toe in a few Zhou Houke.
(3), thromboembolism performance: mucocutaneous petechiae, center is canescence, is more common in a conjunctiva, hard palate mucosa or shirtfront and abdominal skin.Or the Roth point on visible optical fundus, there is the striated of tenderness hemorrhage under fingernail, refer to, the aubergine protuberance of toe end, have the Osler of tenderness to tie, the Silent Neuritis Janeways brief summary in palm or vola, or the thromboembolism sign of brain, kidney, spleen, lung and artery of extremity.
(4), pathologic murmur prompting previously had heart change.The change of original noise character, or newly occur that the diagnostic value of noise is not as acute person.Heart failure can be caused.
(5), ultrasoundcardiogram is attached to " lumps " or " lint sample " the vegetation echo on lobe leaf as seen.Lobe leaf is the motion of flail sample, prompting perforation of valve cusp or rupture of chordae tendineae.
(6), lab testing
1. hemoculture more than at least 2 times same strain positive is important diagnosis basis.
2. erythrocyte reduces, and leukocyte Chang Zhongdu increases, shift to left, and Ear lobe blood can find abnormal histiocyte.
3. erythrocyte sedimentation rate speeds.
, can there is Hypergammaglobulinemia or hypocomplementemia in 4. detection of plasma inspection, immune complex is positive, and some patients's emulsion test positive or rheumatoid factor titre increase.Treponema pallidum agglutination Kahn reaction can false positive.
5. visible albumen, erythrocyte in urine, can have renal failure.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.6 weeks courses for the treatment of.
Matched group oral tetracycline, 0.5g is oral, every 6 hours 1 time, 6 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: transference cure, result of laboratory test is normal, and hemoculture more than 3 times is negative, nothing recurrence in surrounding after drug withdrawal.
Effective: body temperature is normal, hemoculture more than 3 times is negative, but legacy part complication or some lab work do not reach normally.
Invalid: symptom, lab testing lab work are without improvement.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment infective endocarditis, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: blue or green 15 grams of Ludwigia octovalvis (Jacq.) Raven 20 grams, Semen Abietis Delavayi 12 grams, straw sandals, Equisetum pratense 8 grams, Herba Arundinae Chinensis 15 grams, Herba Stellariae dichotomae 20 grams, emblic leafflower fruit 30 grams, Radix Achyranthis Bidentatae 9 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of infective endocarditis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: blue or green 15 grams of Ludwigia octovalvis (Jacq.) Raven 20 grams, Semen Abietis Delavayi 12 grams, straw sandals, Equisetum pratense 8 grams, Herba Arundinae Chinensis 15 grams, Herba Stellariae dichotomae 20 grams, emblic leafflower fruit 30 grams, Radix Achyranthis Bidentatae 9 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of infective endocarditis.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: blue or green 15 grams of Ludwigia octovalvis (Jacq.) Raven 20 grams, Semen Abietis Delavayi 12 grams, straw sandals, Equisetum pratense 8 grams, Herba Arundinae Chinensis 15 grams, Herba Stellariae dichotomae 20 grams, emblic leafflower fruit 30 grams, Radix Achyranthis Bidentatae 9 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of infective endocarditis.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of infective endocarditis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: blue or green 15 parts of Ludwigia octovalvis (Jacq.) Raven 20 parts, Semen Abietis Delavayi 12 parts, straw sandals, Equisetum pratense 8 parts, Herba Arundinae Chinensis 15 parts, Herba Stellariae dichotomae 20 parts, emblic leafflower fruit 30 parts, Radix Achyranthis Bidentatae 9 parts.
2. a kind of Chinese medicine being used for the treatment of infective endocarditis as claimed in claim 1, it is characterized in that, its preparation method is: take: blue or green 15 parts of Ludwigia octovalvis (Jacq.) Raven 20 parts, Semen Abietis Delavayi 12 parts, straw sandals, Equisetum pratense 8 parts, Herba Arundinae Chinensis 15 parts, Herba Stellariae dichotomae 20 parts, emblic leafflower fruit 30 parts, Radix Achyranthis Bidentatae 9 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. a kind of Chinese medicine being used for the treatment of infective endocarditis as claimed in claim 1, it is characterized in that, its preparation method is: take: blue or green 15 parts of Ludwigia octovalvis (Jacq.) Raven 20 parts, Semen Abietis Delavayi 12 parts, straw sandals, Equisetum pratense 8 parts, Herba Arundinae Chinensis 15 parts, Herba Stellariae dichotomae 20 parts, emblic leafflower fruit 30 parts, Radix Achyranthis Bidentatae 9 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. a kind of Chinese medicine being used for the treatment of infective endocarditis as claimed in claim 1, it is characterized in that, its preparation method is: take: blue or green 15 parts of Ludwigia octovalvis (Jacq.) Raven 20 parts, Semen Abietis Delavayi 12 parts, straw sandals, Equisetum pratense 8 parts, Herba Arundinae Chinensis 15 parts, Herba Stellariae dichotomae 20 parts, emblic leafflower fruit 30 parts, Radix Achyranthis Bidentatae 9 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105250878A (en) * | 2015-10-30 | 2016-01-20 | 姜秀芹 | Traditional Chinese medicine for treating sub-acute infective endocarditis |
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Non-Patent Citations (3)
| Title |
|---|
| 周端求: "《草药土方辩证治疗经验集》", 30 September 2011, 湖南科学技术出版 * |
| 周跃庭主编: "《世界传统医学大系》", 30 June 1998, 科学出版社出版 * |
| 江育仁等: "《实用中医儿科学》", 30 September 1995, 上海科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105250878A (en) * | 2015-10-30 | 2016-01-20 | 姜秀芹 | Traditional Chinese medicine for treating sub-acute infective endocarditis |
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Application publication date: 20151028 |