CN103893374A - Traditional Chinese medicine for treating diabetic retinopathy - Google Patents

Traditional Chinese medicine for treating diabetic retinopathy Download PDF

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CN103893374A
CN103893374A CN201410131871.7A CN201410131871A CN103893374A CN 103893374 A CN103893374 A CN 103893374A CN 201410131871 A CN201410131871 A CN 201410131871A CN 103893374 A CN103893374 A CN 103893374A
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chinese medicine
diabetic retinopathy
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herba
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叶葵
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Abstract

The invention relates to a traditional Chinese medicine for treating diabetic retinopathy. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: 30 parts of serpoletleaf sandwort herb, 10 parts of grass of meadow rue, 9 parts of salvia roborowskii, 15 parts of common leafflower herb with roots, 15 parts of Japanese ligusticum leaves, 30 parts of Stachys palustris L, 15 parts of vicia unijuga, 9 parts of coffee senna seeds, 9 parts of Sarcococca ruscifolia Stapf, 10 parts of gum peach, 15 parts of tall monkshood roots and 10 parts of physalis angulata. Clinical experiments verify that the traditional Chinese medicine can safely and effectively treat diabetic retinopathy when used together with western medicines.

Description

A kind of Chinese medicine for the treatment of of diabetic retinopathy
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of of diabetic retinopathy.
Background technology
Diabetic retinopathy (Diabetic retinopathy, DR) is one of microvascular complication that diabetes are the most common and serious.Along with diabetic duration extends, the first sequela of eyes, and can cause macular area edema, ooze out, retinal hemorrhage, vitreous opacity, tractional detachment of retina, can cause patient's visual function impaired, be the main cause of adult's posteriority blinding.This disease state of an illness is complicated and changeable, and visual acuity is poor.Modern medicine is mainly taking blood sugar lowering as main to the treatment of diabetic retinopathy, but undesirable to its anaphase effect, and along with increasing the weight of of the state of an illness, vision sharply declines.There is no at present the medicine of generally acknowledged definite treatment of diabetic retinopathy.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Herba Arenariae Serpyllifoliae [source] is not in the mood for dish Arebarua serpyllifo for pinkwort] herb of ia L..Gather early summer, dries or using fresh herb.[function cures mainly] heat clearing away; Improving eyesight; Cough-relieving.Main liver-heat conjunctival congestion; Pterygium; Pulmonary tuberculosis cough; Laryngopharynx swelling and pain; Gingivitis.
Thalictrum aquilegifolium L. var. sibiricum Regel [source] is cohosh Thalictrum aquilegifolium L. var. sibiricum Regel Thalictrum aquilegifolum L.var.sibiricum Regel et Tiling[T.comtortum L. l; T.aquilegifoliumL.subsp.asiaticum (Nakai) Kitag.] root and rhizome.Uproot in spring, autumn stem and root, remove stem and leaf on the ground, washes away earth, dries.[function cures mainly] clearing away heat-fire; Dampness removing toxic substances.Main calentura is vexed; Damp-heat dysentery; Cough due to lung-heat; Conjunctival congestion and swelling pain; Carbuncle furuncle.
Salvia roborowskii Maxim [source] is the herb of labiate Salvia roborowskii Maxim Salvia roborowskii Maxim..The herb of gathering summer, cleans, and dries.[function cures mainly] liver heat removing; Improving eyesight; Pain relieving.Main conjunctival congestion and swelling pain; Pterygium.
Herba Phyllanthi Urinariae [source] is pinkwort Herba Phyllanthi Urinariae Sagina saginoides (L.) Karsten[Sper-gula saginoides L.] herb.4-5 gathers between the month, cleans; Using fresh herb or dry.[function cures mainly] endogenous wind stopping relieving convulsion; Clearing away heat-damp and promoting diuresis.Main tetanus; Jaundice.
Folium Ligustri pubescentis [source] is the leaf of Oleaceae plants Ligustrum japonicum Thunb. Ligustrum japonicum Thunb.[L.Japonicum Thunb.var.pubescens Koidz..Gather annual or multiple, autumn, using fresh herb or spill ten.[function cures mainly] clearing away liver-fire; Relieving heat toxin.The main vertigo; Acute catarrhal conjunctivitis; Mouth is lean; Tooth is evil; Innominate toxic swelling; Burn due to hot liquid or fire.
Wangjiang green grass or young crops [source] is root or the herb of labiate Stachys palustris L. Stachys palustris L..Gather spring to early winter, cleans using fresh herb or dry.[function cures mainly] heat-clearing and toxic substances removing; Removing heat from blood and promoting blood circulation.Main laryngopharynx swelling and pain; Lung abscess; Pertussis; Dysentery; Acute mastitis; Herpes zoster; The raw cataracta of order; Spitting of blood; Treating swelling and pain by traumatic injury.
Vicia unijuga [source] pulse family Vetch plant Vicia unijuga Vicia unijuga A.Brown, with all herbal medicine.Xia Qiu gathers, and dries.[function cures mainly] tonify deficiency is adjusted liver, regulating QI to relieve pain, clearing away heat and promoting diuresis.For dizzy, body is impractical swollen, stomachache; Furuncle furuncle is controlled in external.
Semen Cassiae Occidemtalis [source] is the seed of leguminous plant Herba cassiae occidentalis Cassia occidentalis L..When October fruit maturation flavescence, extract with strain, dry rear threshing, get seed and dry again.[function cures mainly] liver heat removing, stomach invigorating, relieving constipation, removing toxic substances.Main conjunctival congestion and swelling pain, dizzy feeling of fullness in the head, dyspepsia, stomachache, dysentery, constipation, carbuncle furunculosis.
Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) fruit [source] is the fruit of the wild fan flower of Buxaceae plant Sarcococca ruscifolia Stapf.Autumn, winter, spring picking fruit, using fresh herb or dry.[function cures mainly] nourishing the liver is calmed the nerves.Main dizziness; Order flower; Cardiopalmus; Sleep uneasy night.
Gumshiraz [source] rosaceous plant Fructus Persicae Prunus persica (L.) Batsch, the resin flowing out on trunk.Xia Qiu gathers, and dries.[function cures mainly] invigorates blood circulation, and QI invigorating is quenched the thirst.For diabetes, chyluria, infantile malnutrition.
Radix aconiti sinomontani [source] Ranunculaceae aconitum plant Aconitum sinomontanum Nakai Aconitum sinomontanum Nakai, is used as medicine with root.Xia Qiu gathers, and dries.[function cures mainly] expelling wind and removing dampness, eliminating stasis to stop pain.For lumbago, skelalgia of rheumatism, peratodynia, traumatic injury.
Physalis minima L. [source] Solanaceae monkey flower Fructus Seu Herba Pubescentis Physalis minima L., with all herbal medicine.Xia Qiu gathers, and clean and dry, or using fresh herb.[function cures mainly] clearing away heat-damp and promoting diuresis, expelling phlegm for arresting cough, hard masses softening and resolving.For icterohepatitis, cholecystitis, cold, fever, laryngopharynx swelling and pain, bronchitis, lung abscess, parotitis, orchitis, cystitis, hematuria, the tuberculosis of cervical lymph nodes; Impetigo is controlled in external, eczema, furuncle and phyma.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of of diabetic retinopathy, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective treatment of diabetic retinopathy.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of of diabetic retinopathy, it is characterized in that, be prepared from by the medical material of following weight proportion: 30 parts of Herba Arenariae Serpyllifoliaes, 10 parts of Thalictrum aquilegifolium L. var. sibiricum Regel, 9 parts of Salvia roborowskii Maxims, 15 parts of Herba Phyllanthi Urinariaes, 15 parts of Folium Ligustri pubescentiss, blue or green 30 parts of Wangjiang, 15 parts of Vicia unijuga, 9 parts of Semen Cassiae Occidemtalis, 9 parts of Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) fruits, 10 parts of gumshiraz, 15 parts of Radix aconiti sinomontani, 10 parts of Physalis minima L..
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
Inventor collects 94 examples between JIUYUE 1 years November in 2011 and is diagnosed as the inpatient of diabetes, diabetic retinopathy altogether, the precious disconnected standard of diabetic retinopathy and by stages according to the treasure who formulates in the 3rd Society of Ophthalmology of Chinese Medical Association in 1985 standard of breaking, before all selected patient treatments, turn out to be I~III phase diabetes merging retinopathy through examination of ocular fundus and fundus fluorescein angiography, patient age 50-65 year, course of disease 3-16.Patient is divided at random: treatment group 49 examples, treatment group 45 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
2.1 all patients treat the in the situation that of strict control blood glucose, the capsule that the oral the present invention for the treatment of group makes according to specific embodiment 1, sooner or later respectively once, oral calcium dobesilate (calcium hydrophenyl sulfonate capsule) 500mg simultaneously, every day 2 times.Matched group is oral calcium dobesilate 500mg only, every day 3 times.The February course for the treatment of.
3, efficacy determination and therapeutic outcome
3.1 criterion of therapeutical effect
Effective: more than vision improves two row, microangioma reduces more than 5, and retinal hemorrhage, oozes out absorption, fluoroscopic visualization seepage disappears.Effective: vision raising is less than two row, and microangioma reduces more than 3, retinal hemorrhage, exfiltrating part absorbs.Invalid: vision is constant, retinal hemorrhage, oozes out and microangioma increases the weight of or constant.
3.2 treatment statistical results are in table 1.
Table 1 liang group curative effect comparison
Figure BSA0000102682160000031
Note: ask comparison for two groups, P < 0.05, has significant difference, shows that treatment group is better than matched group
Visible, the medicine cooperation calcium dobesilate that the present invention makes can safe and effective treatment of diabetic retinopathy.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: 30 grams of Herba Arenariae Serpyllifoliaes, 10 grams of Thalictrum aquilegifolium L. var. sibiricum Regel, 9 grams of Salvia roborowskii Maxims, 15 grams of Herba Phyllanthi Urinariaes, 15 grams of Folium Ligustri pubescentiss, blue or green 30 grams of Wangjiang, 15 grams of Vicia unijuga, 9 grams of Semen Cassiae Occidemtalis, 9 grams of Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) fruits, 10 grams of gumshiraz, 15 grams of Radix aconiti sinomontani, 10 grams of Physalis minima L., add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the go out capsule of consumption of normal adult 1.
Be used for the treatment of diabetic retinopathy.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: 30 grams of Herba Arenariae Serpyllifoliaes, 10 grams of Thalictrum aquilegifolium L. var. sibiricum Regel, 9 grams of Salvia roborowskii Maxims, 15 grams of Herba Phyllanthi Urinariaes, 15 grams of Folium Ligustri pubescentiss, blue or green 30 grams of Wangjiang, 15 grams of Vicia unijuga, 9 grams of Semen Cassiae Occidemtalis, 9 grams of Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) fruits, 10 grams of gumshiraz, 15 grams of Radix aconiti sinomontani, 10 grams of Physalis minima L., add 8 times of water, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of diabetic retinopathy.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: blue or green 30 grams of 30 grams of Herba Arenariae Serpyllifoliaes, 10 grams of Thalictrum aquilegifolium L. var. sibiricum Regel, 9 grams of Salvia roborowskii Maxims, 15 grams of Herba Phyllanthi Urinariaes, 15 grams of Folium Ligustri pubescentiss, Wangjiang, 15 grams of Vicia unijuga, Herba cassiae occidentalis give 9 grams, 9 grams of Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) fruits, 10 grams of gumshiraz, 15 grams of Radix aconiti sinomontani, 10 grams of Physalis minima L., add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and to granulate according to this area common process, packaging, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of diabetic retinopathy.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. the Chinese medicine of a treatment of diabetic retinopathy, it is characterized in that, be prepared from by the medical material of following weight proportion: 30 parts of Herba Arenariae Serpyllifoliaes, 10 parts of Thalictrum aquilegifolium L. var. sibiricum Regel, 9 parts of Salvia roborowskii Maxims, 15 parts of Herba Phyllanthi Urinariaes, cover blue or green 30 parts of 15 parts of Folium Camelliae sinensis, Wangjiang, 15 parts of Vicia unijuga, Herba cassiae occidentalis with mat and give 9 parts, 9 parts of Radix Sarcococcae Ruscifoliae (Herba Sarcoclccae Ruscifoliae) fruits, 10 parts of gumshiraz, 15 parts of Radix aconiti sinomontani, 10 parts of Physalis minima L..
CN201410131871.7A 2014-03-26 2014-03-26 Traditional Chinese medicine for treating diabetic retinopathy Pending CN103893374A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352822A (en) * 2014-09-22 2015-02-18 顾燕君 Traditional Chinese medicine for treating diabetic retinopathy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王超英: "糖尿病性视网膜病变中医辩证分型治疗124例临床分析", 《医药论坛杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104352822A (en) * 2014-09-22 2015-02-18 顾燕君 Traditional Chinese medicine for treating diabetic retinopathy

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Application publication date: 20140702