CN103536803A - Medicament for treating cataract and preparation method thereof - Google Patents

Medicament for treating cataract and preparation method thereof Download PDF

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Publication number
CN103536803A
CN103536803A CN201310533539.9A CN201310533539A CN103536803A CN 103536803 A CN103536803 A CN 103536803A CN 201310533539 A CN201310533539 A CN 201310533539A CN 103536803 A CN103536803 A CN 103536803A
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parts
herba
treatment
sheaths
semen
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纪晓
李勇
孙立新
卢纪杰
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纪晓
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Abstract

The invention discloses a medicament for treating cataract and a preparation method thereof, and belongs to the field of Chinese medicines. The effective components of the medicament are prepared from the following raw materials: gentianopsis barbata, cottonrose hibiscus leaves, scaphium scaphigerum, arenaria rhodantha, tibetan barberry, Chinese mahonia leaves, tetrapanax papyriferus, root of common aeschynomene, seed of feather cockscomb, herba equiseti ramosissimi, cordyceps sobolifera, sheaths of henon bamboo shoot, eriocaulon buergerianum, arctium lappa, amaranthus albus and rhod omyrtustomentosa. The medicament disclosed by the invention has the effects of clearing liver and improving vision, clearing away heat and toxic materials, nourishing the liver and nourishing kidney and removing nebula, can be used for both killing bacilli in eyes, diminishing inflammation, eliminating barrier and recovering the eyesight, and has remarkable curative effects of hot eyes and sore red pain, epiphora induced by wind, slight corneal opacity, eye shielding, and eye side red and festering. The medicament disclosed by the invention is convenient to take, easy to absorb, good in curative effect and rapid in effect taking, patients do not need to have operation, so that the risk is small, the purpose of treating both symptoms and root causes is achieved without toxic and side effects, and the medicament has a good effect in treating cataract.

Description

A kind of cataractous medicine and preparation method for the treatment of
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of cataractous medicine and preparation method for the treatment of.
Background technology
Cataract is a kind of disease occurring on the crystalline lens of eyeball the inside, and any lenticular muddiness all can be described as cataract, but when lenticular opacity is lighter, does not affect one's power of vision significantly and by people, is not found or be left in the basket and do not list cataract ranks in; According to investigation, cataract is modal blinding and reason with visual disabilities, the mankind approximately 25% suffer from cataract, cataractous cardinal symptom is visual deterioration, blurred vision, difference due to cataract position and degree, they are also different on the impact of vision, if cataract length is at lenticular periphery, vision can be unaffected, if muddiness is positioned at lenticular central authorities, the lighter's visual deterioration, severe one vision may only be seen manually or light sensation, can show as in addition myopia degree and deepen, and often needs the frequent glasses of changing; Monocular diplopia or polyopia, stationarity shadow or look thing obfuscation at the moment, the symptoms such as photophobia, generally cataractous eye is without erythralgia symptom.
Senile cataract pathogenic factor is up to the present also very not clear, in senile cortical cataract evolution, there is one section of process medically to cry the phase of expansion, phase at this moment, in crystal, there is more moisture content to gather, make its sharply swelling, volume increases, anterior chamber shoals, patient now can feel the quickening of visual deterioration speed, indivedual patients can be expanded due to crystalline lens, the reasons such as anterior chamber shoals, cause high intraocular pressure and cause glaucoma, it is furious that patient can feel, ophthalmalgia, companioned with headache, feel sick, the General Symptomies such as vomiting, vision sharply declines and even loses light sensation, if this glaucoma treatment not in time, to cause permanent loss vision, even if row cataract operation also cannot be saved vision again.
At present, treating cataractous most effectual way is surgical removal treatment, and operative treatment can only take stopgap measures and can not effect a permanent cure; Postcataract may cause a series of complication, and the patient who suffers from hypertension, heart disease or Other diseases should not perform the operation, owing to suffering from cataractous patient, be all old people mostly again, operation meeting brings very large psychological burden and financial burden to them.
Summary of the invention
The invention provides a kind of cataractous medicine and preparation method for the treatment of, medicine of the present invention has the effect of liver heat removing and eyesight improving, heat-clearing and toxic substances removing, nourishing the liver nourishing kidney, improving acuity of vision and removing nebula, both can kill the bacillus in eyes, can antiinflammatory remove barrier again, recover vision, to treatment conjunctival congestion and swelling pain, epiphora induced by wind, pterygium, the red rotten significant curative effect that has in eye limit.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Cataractous medicine and a preparation method, raw material composition and the parts by weight of making described effective ingredient are:
45~70 parts of 49~75 parts of Herba Astragali Sinici of 50~75 parts of Semen Sterculiae Lychnophoraes of 55~80 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
35~56 parts of 37~60 parts of Radix Aeschynomenes indicaes of 40~65 portions of Medulla Tetrapanaciss of 41~68 parts of Mahonia shenii Chun of black stone pearl
30~43 parts of 30~50 parts of Sheaths Phyllostachydis henoniss of 32~51 parts of Periostracum cicadaes of 35~55 parts of Herba equiseti ramosissimis of Semen Celosiae
10~30 parts of 20~35 parts of mountain Shen of 22~39 parts of Herba Amaranthi Viridis of 25~40 parts of Fructus Arctiis of Flos Eriocauli.
Raw material composition and the parts by weight of making described effective ingredient are:
50~67 parts of 51~70 parts of Herba Astragali Sinici of 55~71 parts of Semen Sterculiae Lychnophoraes of 60~75 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
39~53 parts of 40~57 parts of Radix Aeschynomenes indicaes of 44~60 portions of Medulla Tetrapanaciss of 45~65 parts of Mahonia shenii Chun of black stone pearl
32~40 parts of 33~45 parts of Sheaths Phyllostachydis henoniss of 35~48 parts of Periostracum cicadaes of 38~50 parts of Herba equiseti ramosissimis of Semen Celosiae
13~27 parts of 23~30 parts of mountain Shen of 25~35 parts of Herba Amaranthi Viridis of 28~37 parts of Fructus Arctiis of Flos Eriocauli.
Raw material composition and the parts by weight of making described effective ingredient are:
53~63 parts of 55~65 parts of Herba Astragali Sinici of 60~66 parts of Semen Sterculiae Lychnophoraes of 65~70 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
43~50 parts of 45~55 parts of Radix Aeschynomenes indicaes of 47~55 portions of Medulla Tetrapanaciss of 50~60 parts of Mahonia shenii Chun of black stone pearl
34~37 parts of 35~40 parts of Sheaths Phyllostachydis henoniss of 38~45 parts of Periostracum cicadaes of 40~46 parts of Herba equiseti ramosissimis of Semen Celosiae
15~22 parts of 25~27 parts of mountain Shen of 28~32 parts of Herba Amaranthi Viridis of 30~35 parts of Fructus Arctiis of Flos Eriocauli.
Raw material composition and the parts by weight of making described effective ingredient are:
58 parts of 60 parts of Herba Astragali Sinici of 63 parts of Semen Sterculiae Lychnophoraes of 68 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
47 parts of 50 parts of Radix Aeschynomenes indicaes of 51 portions of Medulla Tetrapanaciss of 55 parts of Mahonia shenii Chun of black stone pearl
35 parts of 38 parts of Sheaths Phyllostachydis henoniss of 41 parts of Periostracum cicadaes of 43 parts of Herba equiseti ramosissimis of Semen Celosiae
18 parts of 26 parts of mountain Shen of 30 parts of Herba Amaranthi Viridis of 33 parts of Fructus Arctiis of Flos Eriocauli.
Treat a preparation method for cataractous medicine, comprise following processing step:
(1) Herba Gentianopsis Paludosae, Folium Hibisci Mutabilis, Semen Sterculiae Lychnophorae, Mahonia shenii Chun, Medulla Tetrapanacis, Radix Aeschynomenes indicae, Herba equiseti ramosissimi, Periostracum cicadae and Flos Eriocauli are cleaned, put into container, add the distilled water of 8~12 times of amounts, soak after 4~5 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 50 ℃, relative density is 1.10~1.14, standby;
(2) Fructus Arctii is cleaned, dried, slow fire is fried, and fries to 10~20 minutes, takes out, and grinds into powder, crosses 200 order fine powders, standby;
(3) mountain Shen is cleaned, immerse 85% alcohol solution dipping 1-2 hour of 5 times of amounts, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.20~1.25, standby;
(4) black stone pearl, Semen Celosiae and Sheaths Phyllostachydis henonis are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 120 order fine powders, standby;
(5) Herba Astragali Sinici and Herba Amaranthi Viridis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(6) the made thick paste in above-mentioned steps (1)-(5), fine powder and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make tablet or capsule, both the cataractous medicine for the treatment of of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Gentianopsis Paludosae: hardship, cold in nature.GUIXIN, Liver Channel.Heat-clearing and toxic substances removing; Reducing swelling and alleviating pain.Main fever caused by exogenous pathogens; Hepatitis; Cholecystitis; Headache conjunctival congestion; Wound swells and ache; Furuncle toxic swelling.
Folium Hibisci Mutabilis: pungent; Bitter; Cool.Return lung, Liver Channel.Qingfei Liangxue; Removing toxic substances and promoting subsidence of swelling.Main cough due to lung-heat; Conjunctival congestion and swelling pain; Swollen ulcer drug; Malignant boil; Herpes zoster is burdened with; Impetigo; Pyelonephritis; Burn due to hot liquid or fire; Venom; Traumatic injury.
Semen Sterculiae Lychnophorae: sweet in the mouth; Light; Cool in nature.Return lung, large intestine channel.Clearing heat and moistening lung, liyan jiedu, loosening bowel to relieve constipation.For lung-heat celostomia, dry cough without phlegm, pharyngodynia with dryness, accumulation of heat just closes, headache conjunctival congestion.Be used for out lung qi, clearing away lung-heat.The < < detailed outline > > that picks up any lost article from the road carries: " control fire and close pox; and control all heat symptom-complex impairments caused by overstrain and tell nosebleed hematochezia; sterilization is driven away summer heat; time row acute conjunctivitis, toothache angrily, eats under malnutrition due to parasitic infestation; hemorrhoid fistulae; dry cough without phlegm, hectic fever due to YIN-deficiency interior-heat, three warmers fire disease.”
Herba Astragali Sinici: Gan Xin; Flat.GUIXIN, liver, lung meridian.Heat-clearing and toxic substances removing, dispelling pathogenic wind for improving eyesight, cooling blood for hemostasis.Main throat pain, wind-phlegm cough, conjunctival congestion and swelling pain, furuncle, herpes zoster, scabies, hemorrhoid, bleeding from the gum, traumatic hemorrhage, menoxenia, leukorrhagia, thrombocytopenic purpura.< < medical herbs handbook > > carries: " dispelling pathogenic wind for improving eyesight, analgesic diuresis.Control wind-phlegm cough, malaria, acute catarrhal conjunctivitis, traumatic hemorrhage.”
Black stone pearl: bitter in the mouth; Cold in nature.Return liver, large intestine channel.Heat clearing and damp drying; Eliminating fire and detoxication.Main diarrhea due to damp-heat; Dysentery; Jaundice; Conjunctival congestion and swelling pain; Trauma infection contamination.
Mahonia shenii Chun: bitter in the mouth, cold in nature, nontoxic.Enter the heart, liver two warps.The stomach-fire that clears away heart-fire, removing toxic substances.Control YANG jaundice, hematodiarrhoea, acute conjunctivitis; External treatment knife injury, heat clearing away, dampness.Main hygropyretic dysentery; Diarrhoea; Jaundice; Conjunctival congestion and swelling pain; Burn and scald.
Medulla Tetrapanacis: sweet, light, be slightly cold.Attach to the lung and stomach meridians.Clearing away heat and promoting diuresis, ventilation stimulating milk secretion.For hygropyrexia dark coloured urine, the puckery pain of gonorrhea, edema oliguria, eliminating the pathogens from the lung, puerpera's galactostasis, blurred vision, nasal obstruction.< < Japan hanako materia medica > > calls it, and " improving eyesight, brings down a fever, and expedites the emergence of lower eyelid, stimulating milk secretion.”
Radix Aeschynomenes indicae: sweetness and bitterness; Cold.Return lung, stomach, urinary bladder channel.Clearing away heat-damp and promoting diuresis, removing food stagnancy, removing toxic substances.Main stranguria with blood, has loose bowels, dysentery, infantile malnutrition, blurred vision, toothache, furuncle.< < Jiangxi medical herbs > > carries: " clearing away heat-damp and promoting diuresis, detumescence hemostasis.”
Semen Celosiae: hardship; Cold in nature.Return Liver Channel.The people's heat of dispelling; Clearing away liver-fire; Improving acuity of vision and removing nebula.Main conjunctival congestion and swelling pain; The nebula of looking unfamiliar film; Blurring of vision; Hypertension; Epistaxis; Skin wind heat pruritus; Skin ulcer tinea.< < property of medicine opinion > > carries: " the dirty pyretic toxicity dotting punch for the treatment of the liver, red barrier, optic atrohic blindness, nebula swell.Main malignant boil scabies scabies, controls the inferior portion worm and reveals skin ulcer.”
Herba equiseti ramosissimi: sweet; Bitter; Flat; Nontoxic; Be slightly cold.GUIXIN, liver, stomach, urinary bladder channel.Liver heat removing and eyesight improving; Hemostasis; Inducing diuresis for treating stranguria syndrome; Main anemopyretic cold; Cough; Conjunctival congestion and swelling pain; Nebula; Epistaxis; Hematuria; Discharging fresh blood stool; Stranguria; Jaundice; Leukorrhagia; Fracture.< < Traditional Chinese Medicine in Sichuan will > > carries: " clearing away heart-fire, removes hectic fever, scattered clouds nebula.Control epidemic hemorrhagic conjunctivitis, puckery pain, overflow tear and conjunctival congestion and swelling pain, and treat nose bleeding.”
Periostracum cicadae: sweet; Cold; Nontoxic.Return lung, Liver Channel.Dispelling wind and heat pathogens; Rash; Relieving spasm by subduing liver-wind; Improving acuity of vision and removing nebula.Main affection due to external wind and heat; Heating; Dizzy; Pharyngalgia; The single board computer rash initial stage; Rash goes out not smooth; Infantile convulsion; Conjunctival congestion and swelling pain; Pterygium; Night cry.Modern medicine pharmacological testing proves, Cordyceps cicadae Shing has the effect of tonifying liver improving eyesight, is applicable to muscae volitantes, cataract, nyctalopia, blurred vision etc.
Sheaths Phyllostachydis henonis: sweet; Light; Cold.Improving acuity of vision and removing nebula, argument nebula.The < < detailed outline > > that picks up any lost article from the road carries: " can remove corneal nebula, the same Fel Ursi of merit.”
Flos Eriocauli: pungent, sweet, flat.Return liver, lung meridian.Dispelling wind and heat pathogens, improving eyesight, nebula removing.For wind heat conjunctival congestion, the photophobia that swells and ache, the nebula of looking unfamiliar film, headache due to pathogenic wind-heat.< < Compendium of Materia Medica > > carries: " the light property of Flos Eriocauli body is floating, can the bright dividing line of up sun.Allly control all diseases in order, add and with it, very good.The merit of improving acuity of vision and removing nebula, like on Flos Chrysanthemi also." modern medicine study confirmation, Flos Eriocauli has the effect for the treatment of wind-heat of liver channel, conjunctival congestion and swelling pain, the raw cataracta of order, headache due to pathogenic wind-heat, nyctalopia.
Fructus Arctii: acrid in the mouth; Bitter; Cold in nature.Return lung; Stomach warp.Dispelling wind and heat pathogens; Heat-clearing and toxic substances removing rash; Lung qi dispersing sore-throat relieving is loose swollen, and improving eyesight invigorating middle warmer, except wind wound.< < Bencao Jingshu > > carries: " disliking in fact, is that loose wind is except the key medicine of thermal detoxification.Pungent can eliminating stagnation, hardship can expel the heat-evil, the loose visceral-qi of accumulation of heat is clear and bright, therefore improving eyesight and invigorating middle warmer." modern pharmacological research shows, Fructus Arctii water logging agent has inhibitory action in various degree to various pathogens; Its extract has the effect of significant blood sugar lowering and improving eyesight; Contained Arctiin has and reduces blood pressure momently and slight diuresis, discharge function.
Herba Amaranthi Viridis: sweet; Light; Cold in nature.Return large intestine, small intestine meridian.Heat clearing away; Dampness removing; Removing toxic substances.Main dysentery; Have loose bowels; Hot urination; Skin ulcer is swollen; Snakeworm sting; Ulcerative gingivitis.Jiangxi < < medical herbs handbook > > carries: " heat clearing away, removing toxic substances, diuresis, pain relieving, improving eyesight.”
Mountain Shen: sweet puckery, flat.Nourish blood, hemostasis, astringing intestine to stop diarrhea, controlling nocturnal emission with astringent drugs.Control blood deficiency, spit blood, epistaxis, has blood in stool, dysentery, proctoptosis, tinnitus, seminal emission, metrorrhagia, leukorrhagia.The < < detailed outline > > that picks up any lost article from the road carries: " nourish blood, improving eyesight.”
The present invention compared with prior art, has following beneficial effect:
1, medicine of the present invention has the effect of liver heat removing and eyesight improving, heat-clearing and toxic substances removing, nourishing the liver nourishing kidney, improving acuity of vision and removing nebula, both can kill the bacillus in eyes, can antiinflammatory remove barrier again, recover vision, to treatment conjunctival congestion and swelling pain, epiphora induced by wind, pterygium, the red rotten significant curative effect that has in eye limit.
2, drug administration of the present invention facilitates, is easy to absorption, good effect, instant effect, patient without operation, and risk is little, reaches the object for the treatment of both the principal and secondary aspects of a disease, has no side effect, and treatment cataract is had to good effect.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
Herba Gentianopsis Paludosae 75g Folium Hibisci Mutabilis 71g Semen Sterculiae Lychnophorae 70g Herba Astragali Sinici 67g
Black stone pearl 65g Mahonia shenii Chun 60g Medulla Tetrapanacis 57g Radix Aeschynomenes indicae 53g
Semen Celosiae 50g Herba equiseti ramosissimi 48g Periostracum cicadae 45g Sheaths Phyllostachydis henonis 40g
Flos Eriocauli 37g Fructus Arctii 35g Herba Amaranthi Viridis 30g mountain Shen 27g.
Treat a preparation method for cataractous medicine, comprise following processing step:
(1) Herba Gentianopsis Paludosae, Folium Hibisci Mutabilis, Semen Sterculiae Lychnophorae, Mahonia shenii Chun, Medulla Tetrapanacis, Radix Aeschynomenes indicae, Herba equiseti ramosissimi, Periostracum cicadae and Flos Eriocauli are cleaned, put into container, add the distilled water of 8~12 times of amounts, soak after 4~5 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 50 ℃, relative density is 1.10~1.14, standby;
(2) Fructus Arctii is cleaned, dried, slow fire is fried, and fries to 10~20 minutes, takes out, and grinds into powder, crosses 200 order fine powders, standby;
(3) mountain Shen is cleaned, immerse 85% alcohol solution dipping 1-2 hour of 5 times of amounts, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.20~1.25, standby;
(4) black stone pearl, Semen Celosiae and Sheaths Phyllostachydis henonis are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 120 order fine powders, standby;
(5) Herba Astragali Sinici and Herba Amaranthi Viridis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(6) the made thick paste in above-mentioned steps (1)-(5), fine powder and juice are mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make tablet or capsule, both the cataractous medicine for the treatment of of the present invention.
Usage and dosage: oral three times of every day of adult, each two; Within seven days, be a course for the treatment of, take effect a common course for the treatment of, three to four recoveries from illness course for the treatment of.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
Herba Gentianopsis Paludosae 70g Folium Hibisci Mutabilis 66g Semen Sterculiae Lychnophorae 65g Herba Astragali Sinici 63g
Black stone pearl 60g Mahonia shenii Chun 55g Medulla Tetrapanacis 55g Radix Aeschynomenes indicae 50g
Semen Celosiae 46g Herba equiseti ramosissimi 45g Periostracum cicadae 40g Sheaths Phyllostachydis henonis 37g
Flos Eriocauli 35g Fructus Arctii 32g Herba Amaranthi Viridis 27g mountain Shen 22g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
Herba Gentianopsis Paludosae 68g Folium Hibisci Mutabilis 63g Semen Sterculiae Lychnophorae 60g Herba Astragali Sinici 58g
Black stone pearl 55g Mahonia shenii Chun 51g Medulla Tetrapanacis 50g Radix Aeschynomenes indicae 47g
Semen Celosiae 43g Herba equiseti ramosissimi 41g Periostracum cicadae 38g Sheaths Phyllostachydis henonis 35g
Flos Eriocauli 33g Fructus Arctii 30g Herba Amaranthi Viridis 26g mountain Shen 18g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is:
Herba Gentianopsis Paludosae 65g Folium Hibisci Mutabilis 60g Semen Sterculiae Lychnophorae 55g Herba Astragali Sinici 53g
Black stone pearl 50g Mahonia shenii Chun 47g Medulla Tetrapanacis 45g Radix Aeschynomenes indicae 43g
Semen Celosiae 40g Herba equiseti ramosissimi 38g Periostracum cicadae 35g Sheaths Phyllostachydis henonis 34g
Flos Eriocauli 30g Fructus Arctii 28g Herba Amaranthi Viridis 25g mountain Shen 15g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.Embodiment 5
The raw material of effective ingredient of the present invention forms and weight is:
Herba Gentianopsis Paludosae 60g Folium Hibisci Mutabilis 55g Semen Sterculiae Lychnophorae 51g Herba Astragali Sinici 50g
Black stone pearl 45g Mahonia shenii Chun 44g Medulla Tetrapanacis 40g Radix Aeschynomenes indicae 39g
Semen Celosiae 38g Herba equiseti ramosissimi 35g Periostracum cicadae 33g Sheaths Phyllostachydis henonis 31g
Flos Eriocauli 28g Fructus Arctii 25g Herba Amaranthi Viridis 23g mountain Shen 13g.
Process for preparing medicine processing step and the usage and dosage of the present embodiment are identical with embodiment 1.Clinical data:
1, case selection:
As the cataractous medicine for the treatment of, select the routine clinical observation of cataract patient 400 of making a definite diagnosis.
Patient is divided into two groups for the treatment of first group and contrast second groups at random, treatment first group 200 examples, male's 97 examples wherein, women's 103 examples, 46~75 years old age, 56.6 years old mean age, the shortest person of the course of disease 6 months, elder 21 years, average 8.7 years.Contrast second group 200 examples, male's 95 examples wherein, women's 105 examples, 43~70 years old age, 54.5 years old mean age, the shortest person of the course of disease 5 months, elder 19 years, average 8.3 years.The course of disease, the degrees of symptoms for the treatment of first group and two groups of cases of contrast second group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment first group is taken medicine of the present invention, and treatment first forms oral three times of people every day, each two; Within seven days, be a course for the treatment of, take effect a common course for the treatment of, three to four recoveries from illness course for the treatment of.
Contrast second group external Benzydalysine eye drop, eye drip, three times on the one, once two or follow the doctor's advice ten days is a course for the treatment of, and take effect five courses for the treatment of, and the person of being in a bad way is conventionally invalid.
3, efficacy determination:
(1) cure: by treating the transference cures such as rear blurred vision, it is normal that functional activity recovers, and indices recovers normal on inspection.
(2) effective: by treating the symptoms such as rear blurred vision substantially or most of disappearance, indices recovers substantially on inspection.
(3) effective: by treating the symptoms such as rear blurred vision, to be clearly better or to take a turn for the better, through inspection indexing section, take a turn for the better.
(4) invalid: unchanged or increase the weight of by treating rear symptom.
4, result:
Select in the treatment first group of medicine of the present invention, cure 80 examples, effective 72 examples, effective 45 examples, invalid 3 examples, cure rate 40%, total effective rate 98.5%.
In contrast second group, cure 30 examples, effective 45 examples, effective 50 examples, invalid 75 examples, cure rate 15%, total effective rate 62.5%.
Above result demonstration, the cure rate for the treatment of first group and total effective rate are apparently higher than contrast second group.Model case is given an example:
1, temperature certain, man, 72 years old, people from Baoding, suffered from cataract more than 6 years, because heart is bad, dare not perform an operation, can only medication treatment, between 6 years, priority is used the cataractous medicine of multiple treatment disease of eye, its effect is undesirable; After take medicine of the present invention after the course for the treatment of, the symptoms such as blurred vision are clearly better, and take medicine after two courses for the treatment of, cataract symptom disappears completely, vision restoration is normal.
2, Bai, female, 65 years old, people from Datong, eyes were suffered from cataract more than 3 years, and vision only has 0.3,0.4, because heart is bad, be difficult for operative treatment, can only medication treat, take the present invention and treat cataractous medicine after two courses for the treatment of, malaise symptoms disappears entirely, continue to strengthen treatment, take again after the course for the treatment of, vision restoration is to normal level.
3, Song, man, 56 years old, people from Shenyang, Liaoning, right eye sensation vision declines gradually, blurred vision, a backsight thing sensitization sense in three months, the unintelligible Chu that do not see, remove immediately examination in hospital, right vision is only 0.2, is diagnosed as senile cataract, owing to having a delicate constitution, patient requires to take the present invention and treats cataractous medicine, after the course for the treatment of, vision makes moderate progress, and continues to strengthen treatment, takes again two courses for the treatment of, fundamental symptoms disappears, through looking into right vision, revert to 0.6, follow up a case by regular visits to, so far not in recurrence.
4, Cai, female, 45 years old, people from Changchun, Jilin, because operating pressure is large, often headache, two eye visions decline, and see that thing is fuzzy, through examination in hospital, are diagnosed as acute cataract; Take medicine of the present invention after the course for the treatment of, see that the symptoms such as thing is fuzzy disappear substantially, continue to take after the course for the treatment of, symptom disappears completely, and vision restoration is normal, follows up a case by regular visits to without recurrence after 1 year.

Claims (5)

1. treat a cataractous medicine, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
45~70 parts of 49~75 parts of Herba Astragali Sinici of 50~75 parts of Semen Sterculiae Lychnophoraes of 55~80 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
35~56 parts of 37~60 parts of Radix Aeschynomenes indicaes of 40~65 portions of Medulla Tetrapanaciss of 41~68 parts of Mahonia shenii Chun of black stone pearl
30~43 parts of 30~50 parts of Sheaths Phyllostachydis henoniss of 32~51 parts of Periostracum cicadaes of 35~55 parts of Herba equiseti ramosissimis of Semen Celosiae
10~30 parts of 20~35 parts of mountain Shen of 22~39 parts of Herba Amaranthi Viridis of 25~40 parts of Fructus Arctiis of Flos Eriocauli.
2. a kind of cataractous medicine for the treatment of according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
50~67 parts of 51~70 parts of Herba Astragali Sinici of 55~71 parts of Semen Sterculiae Lychnophoraes of 60~75 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
39~53 parts of 40~57 parts of Radix Aeschynomenes indicaes of 44~60 portions of Medulla Tetrapanaciss of 45~65 parts of Mahonia shenii Chun of black stone pearl
32~40 parts of 33~45 parts of Sheaths Phyllostachydis henoniss of 35~48 parts of Periostracum cicadaes of 38~50 parts of Herba equiseti ramosissimis of Semen Celosiae
13~27 parts of 23~30 parts of mountain Shen of 25~35 parts of Herba Amaranthi Viridis of 28~37 parts of Fructus Arctiis of Flos Eriocauli.
3. a kind of cataractous medicine for the treatment of according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
53~63 parts of 55~65 parts of Herba Astragali Sinici of 60~66 parts of Semen Sterculiae Lychnophoraes of 65~70 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
43~50 parts of 45~55 parts of Radix Aeschynomenes indicaes of 47~55 portions of Medulla Tetrapanaciss of 50~60 parts of Mahonia shenii Chun of black stone pearl
34~37 parts of 35~40 parts of Sheaths Phyllostachydis henoniss of 38~45 parts of Periostracum cicadaes of 40~46 parts of Herba equiseti ramosissimis of Semen Celosiae
15~22 parts of 25~27 parts of mountain Shen of 28~32 parts of Herba Amaranthi Viridis of 30~35 parts of Fructus Arctiis of Flos Eriocauli.
4. a kind of cataractous medicine for the treatment of according to claim 1, is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
58 parts of 60 parts of Herba Astragali Sinici of 63 parts of Semen Sterculiae Lychnophoraes of 68 parts of Folium Hibisci Mutabiliss of Herba Gentianopsis Paludosae
47 parts of 50 parts of Radix Aeschynomenes indicaes of 51 portions of Medulla Tetrapanaciss of 55 parts of Mahonia shenii Chun of black stone pearl
35 parts of 38 parts of Sheaths Phyllostachydis henoniss of 41 parts of Periostracum cicadaes of 43 parts of Herba equiseti ramosissimis of Semen Celosiae
18 parts of 26 parts of mountain Shen of 30 parts of Herba Amaranthi Viridis of 33 parts of Fructus Arctiis of Flos Eriocauli.
5. as described in claim 1-4 any one, treat a preparation method for cataractous medicine, it is characterized in that: comprise following processing step:
(1) Herba Gentianopsis Paludosae, Folium Hibisci Mutabilis, Semen Sterculiae Lychnophorae, Mahonia shenii Chun, Medulla Tetrapanacis, Radix Aeschynomenes indicae, Herba equiseti ramosissimi, Periostracum cicadae and Flos Eriocauli are cleaned, put into container, add the distilled water of 8~12 times of amounts, soak after 4~5 hours, boil 3~4 hours, extract; Again add 6~8 times of amount distilled water, boil 2~3 hours, extract; Finally, add 4~6 times of amount distilled water, heated and boiled 1~2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, be condensed into the thick paste that at 50 ℃, relative density is 1.10~1.14, standby;
(2) Fructus Arctii is cleaned, dried, slow fire is fried, and fries to 10~20 minutes, takes out, and grinds into powder, crosses 200 order fine powders, standby;
(3) mountain Shen is cleaned, immerse 85% alcohol solution dipping 1-2 hour of 5 times of amounts, heating evaporation, under 60 ℃ of environment of simmer down to, the thick paste of relative density 1.20~1.25, standby;
(4) black stone pearl, Semen Celosiae and Sheaths Phyllostachydis henonis are mixed, after mix homogeneously, carry out pulverization process, grind into powder, cross 120 order fine powders, standby;
(5) Herba Astragali Sinici and Herba Amaranthi Viridis are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice standby;
(6) made thick paste, fine powder and the juice in above-mentioned steps (1)-(5) is mixed, add adjuvant, utilize modern advanced pharmacy science and technology, make tablet or capsule, obtain the cataractous medicine for the treatment of of the present invention.
CN201310533539.9A 2013-11-03 2013-11-03 Medicament for treating cataract and preparation method thereof Pending CN103536803A (en)

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CN105055985A (en) * 2015-09-25 2015-11-18 王金平 Medicament for treating cataract and preparation method thereof
CN106822303A (en) * 2015-12-03 2017-06-13 黄小兵 A kind of medicine for treating cataract

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103860736A (en) * 2014-04-05 2014-06-18 赵凤娥 Chinese herba preparation for treating cataract and preparation method thereof
CN105055985A (en) * 2015-09-25 2015-11-18 王金平 Medicament for treating cataract and preparation method thereof
CN106822303A (en) * 2015-12-03 2017-06-13 黄小兵 A kind of medicine for treating cataract

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Application publication date: 20140129