CN106955312A - Cataract of old people and its medicine - Google Patents

Abstract

The present invention relates to cataract of old people and its medicine, pharmaceutical technology field, solves the problems, such as the treatment of cataract of old people, by the pathogenesis for analyzing cataract of old people, from a variety of suitable treatments Chinese medicine as medicine, it is characterized in that being combined by following each traditional Chinese medicine quality part ratio：10 parts of wintercherry fruit or calyx, 10 parts of ginseng, 12 parts of Chinese small iris, 10 parts of honeysuckle, 12 parts of saline cistanche, 10 parts of the root bark of tree peony, 10 parts of the fruit of Chinese wolfberry, 12 parts of the dried rhizome of rehmannia, 10 parts of the root bark of Chinese wolf-berry, 10 parts of trollflower, 8 parts of Radix Notoginseng powder, 10 parts of Semen Cuscutae, 3 parts of pearl powder, 10 parts of mung bean, 7 parts of Radix Glycyrrhizae.

Description

Cataract of old people and its medicine

Technical field

The present invention relates to cataract of old people and its medicine, more particularly to be plurality of Chinese combination treatment Medicine, belongs to medicine technology field.

Background technology

Cataract of old people (senile cataract), is most common cataract type.It is more common in more than 50 years old The elderly, increases the incidence of disease with the age and increases.It is believed that it is relevant with the retrogression that old metabolism slowly occurs.But mostly Number case disease progression is slow, and does not affect one's power of vision.

According to the World Health Organization (WHO) relevant report, with world population's astogeny, age-related cataract is First cause as whole world blinding and inpairment of vision.2002, there was 37,000,000 blinding population in the WHO statistics whole world, white interior Hinder blinding number up to 17,000,000 (47%), and expect the blinding number of the year two thousand twenty cataract up to 4,000 ten thousand.

1996, start that Chinese two areas have been carried out to prevent blind under the support of the Chinese institute of ophthalmology of WHO and the U.S. Control blind project appraisal research.Result of study is shown, in the crowd of 50 years old and more than 50 years old, the burden on society rate of cataract blind person (number of operative treatment need to be carried out by being blinded because of cataract for 50 years old and more than 50 years old for every 100) two places area is respectively 1.63% He 3.80%, averagely about 2.70%；And cataract surgical coverage is only 50%.This result shows the people 50 years old and the above In group, still there is the artificial cataract blind person of half i.e. 1.35%.There will be 2,900,000 cataract blind persons to be badly in need of operation in the whole country Treatment.According to estimates, the year two thousand twenty Chinese population is up to 1,500,000,000, and 50 years old and upper crowd account for total population ratio and will also risen to 25.00%, calculated by this development trend, 506.25 ten thousand people are just up to the Chinese cataract blind person number of the year two thousand twenty, it is more existing In nearly 1 times of the cataract blindness number increase of accumulation.

Cataract of old people, its cause of disease is complex, it may be possible to the synthesis result of many factors.The main cause of disease is (1) It is physiological aging：Metabolism decline, hardening dehydration and long-term adjustment anxiety etc..(2) it is malnutritive：Whole body and locally malnutrition, Vascular sclerosis, ciliary epithelium denaturation etc..(3) radiation injury：Infrared ray, ultraviolet, x-ray and other electromagnetic waves.(4) general metabolism And endocrine disturbance etc..Correlative study shows, drinking too much, all age-related cataract such as smoking is more, women 's fertility is more Generation into positive correlation.In addition, the other factors such as factor such as aging, gene is also an importance.

Cataract of old people pathogenesis is mainly relevant with oxidative damage, and disulphide, first are formd in cataract crystal There is reducible key in methyllanthionine, cysteic acid and the reducible polymer of HMW, cytoplasm-epicyte protein； Reduced glutathione (GSH) is reduced in cataract crystal, oxidized form of glutathione (GSSG) is combined with protein and mixing Disulphide increase；Cell membrane disintegration, MDA are formed, and the metabolic activity of oxidation-sensitive are reduced, potentiality oxide concentration Rise etc..With the increase at age, a series of changes of crystal, such as crystal turn yellow, and point out have the accumulation of some pigments；HMW Albumen increase reduces crystal transparency, and the structure of albumen changes, and some active groups appear, and these changes are vulnerable to The infringement of oxidation.

Cataract of old people is eyes disease, but two morbidities can have priority.Cardinal symptom patient feels to have at the moment and fixed not Dynamic stain, in gradual, Silent Neuritis visual impairment.It is different according to phacoscotasmus position, can have monodiplorpia, it is many depending on and bend Light change etc..Position difference is initially formed by muddiness, age-related cataract is divided into cortex, nuclearity and lower 3 kinds of Lens capsular Type, it is most common with cortical cataract.

1st, cortical cataract (cortical cataract) this be the most common type of age-related cataract, about Account for 70%.

2nd, nuclear cataract (nuclear cataract) is rare compared with cortical cataract, accounts for 20%.This type morbidity compared with It is early, start within general 40 years old or so, make slow progress, often need the several years to many decades.Muddiness starts from embryonic nucleus or adult's core, until arriving into People's core is completely muddy.Early stage lens nucleus is in yellow, and periphery is transparent, and eyesight is unaffected.With the increase of lens nucleus density, Refractive power strengthens, and eyesight is decreased obviously, and its color also gradually becomes brown color or brownish black.

3rd, cataract (subcapsular cataract) is that cortex shallow-layer under posterior capsulotomy goes out under Lens capsular Existing yellow is muddy, small vacuole and golden yellow or white crystals sample particle is mingled with therebetween, outward appearance is like crispy rice shape.Due to muddy position In optical axis area, early stage may occur in which vision disorder.Development of cataracts is slow under Lens capsular, and the later stage merges cortex of lens and core Muddiness, finally develops into mature cataract.

The diagnosis of age-related cataract should be crystalline with ophthalmoscope or examination with slitlamp microscope after big pupil is dissipated Body.It can be made and clarified a diagnosis according to the form and vision condition of phacoscotasmus.When hypopsia and phacoscotasmus situation When not meeting, should further it check, searching causes the other diseases of visual impairment, it is to avoid leaked because of the diagnosis of phacoscotasmus Examine other illness in eye.

It is still most basic, maximally effective means that the cataract operation for causing vision disorder, which is treated,.Drug therapy is interior in vain Although the research of barrier has the medicine for also there are many treatment cataract on very long history, medical market, all do not affirm Conclusion.

Operative treatment：Cataract operation progress is extremely notable, especially to the later stage seventies, using posterior chamber intraocular lenses energy Ideally the dioptric after correction cataract extraction, postoperative to recover eyesight rapidly, sets up binocular single vision and stereoscopic vision, makes patient The good visual function that can be returned to before illness.For old age it is long-term disease bed, can not the person of taking care of oneself, simply extract eyeball.

Drug therapy：Over nearly 10 years, the research of medicine cataract has been made significant headway, and what is had has been used to clinic, What is had achieves the success of zoopery, including the anti-quinone body preparation of sulfur-bearing system, aldose reductase inhibitor, vitamin and energy Mixture, natural extract etc. are measured, such as Guttae Phacosylini is fine, glutathione, vitamin C, celestial being Nuo Linte, C16H8N2O5 can carry out part Or whole body therapeutic.

The content of the invention

Cataract of old people be optic nerve systematicness, feature, viral disease, with traditional Chinese medicine viewpoint analysis it is senile in vain Cataract or glaucoma, belongs to nourishing kidney-yin, easily gets ecited, and wet poison is handed over vehement scorching and obtains this disease with the fire of deficiency type, therefore, should be with enriching yin and nourishing kidney, heat-clearing Removing toxic substances, the Chinese medicine of anti-inflammatory fall fire are combined into therapeutic scheme.

Cataract of old people and its medicine are combined by following each traditional Chinese medicine quality part ratio：10 parts of wintercherry fruit or calyx, people 10 parts of ginseng, 12 parts of Chinese small iris, 10 parts of honeysuckle, 12 parts of saline cistanche, 10 parts of the root bark of tree peony, 10 parts of the fruit of Chinese wolfberry, 12 parts of the dried rhizome of rehmannia, the root bark of Chinese wolf-berry 10 Part, 10 parts of trollflower, 8 parts of Radix Notoginseng powder, 10 parts of Semen Cuscutae, 3 parts of pearl powder, 10 parts of mung bean, 7 parts of Radix Glycyrrhizae.

Property of medicine effect of each Chinese medicinal ingredients in lower surface analysis cataract of old people and its medicine.Wintercherry fruit or calyx, is Solanaceae Perennial herb, medicinal fruit has clearing heat and detoxicating, the function of antibechic diuresis.Ginseng reinforces vital energy, can veins takes off admittedly, tonifying spleen benefit Lung, promote the production of body fluid, calm the nerves, for it is physically weak to be taken off, spleen eating less, the deficiency syndrome of the lung are breathed with cough, injury thirst, Heat Diabetes, prolonged illness void are thin, heart failure The chronic diseases marked by deficiency of vital energy such as exhaust.The sub- heat-clearing of Chinese small iris, dampness removing stops blooding, removing toxic substances, controls jaundice, and rush down dysentery is spitted blood, bleeding from five sense organs or subcutaneous tissue, metrorrhagia, leukorrhea, larynx numbness, carbuncle swells. Honeysuckle heat-clearing, removing toxic substances, controls warm disease heating, toxic-heat and blood stasis, large carbuncle, pyogenic infections, scrofula, anal fistula.Saline cistanche kidney tonifying, strengthening the essence is moisturized, Laxation, is controlled under impotence in male, female sterility, band, metrorrhagia, waist and knee crymodynia, blood depletion constipation.The root bark of tree peony thoughts of returning home, clearing heat and cooling blood, Huoxue San " The stasis of blood, nourishing Yin and falling fire, throat, diuresis, anti-inflammatory is calm, cooling.The fruit of Chinese wolfberry is sweet, mild-natured, enters liver and kidney channel, nourshing kidney, moistening lung, Liver-kidney Yin deficiency is controlled in tonifying liver, improving eyesight, soreness and weakness of waist and knees, and dizzy, dizzy, many tears of blurred vision, cough due to consumptive disease is quenched one's thirst, seminal emission.The heat-clearing of fresh ground Promote the production of body fluid, cool blood, hemostasis, for consumption of YIN caused by febrile disease, the deep red polydipsia of tongue, spot dermexanthesis, bleeding from five sense organs or subcutaneous tissue, abscess of throat.The root bark of Chinese wolf-berry, clearind deficient heat is rushed down Lung-fire, cool blood, main hectic fever due to yin deficiency.Trollflower is rich in alkaloid and Flavonoid substances, through science development on the basis of hired facing-up The globeflower tea processed, have effects that anti-inflammatory quench the thirst, throat-benefiting, clearing heat and detoxicating, toxin-expelling and face nourishing, to chronic pharyngitis, Larynx fire, tonsillitis have good therapeutic effect.Radix Notoginseng powder heat-clearing dissipate blood, stimulate the circulation of the blood and cause the muscles and joints to relax, blood activating and promoting tissue regeneration, improve body immune Power, flutters that the stasis of blood is swollen, obstruction of qi in the chest angina, abdominal mass, blood stasis, sore, carbuncle and painful swelling available for falling.Semen Cuscutae filling liver kidney, benefiting quintessence, improving eyesight is controlled Soreness of waist and knee joint, seminal emission, quenches one's thirst, dripping urination, mesh is dark.Pearl powder can strengthen body immunity, supplement calcium, Bao Chunyan and decline, change Kind sleep, treatment ulcer, nourish the liver to improve visual acuity, secondary buck.Mung bean has clearing heat and detoxicating, obvious effect relieved summer heat of quenching the thirst.Radix Glycyrrhizae is town Eliminating the phlegm medicine is coughed, effect rather extensively, in traditional Chinese herbal decoction and Chinese patent drug compatibility, commonly uses the beneficial spleen of its tonifying Qi and middle emergency, mediation The effect of all medicines.

Cataract of old people and its beneficial effect of medicine invention are：Inventor is belonged to by analyzing cataract of old people In optic nerve systematicness, feature, viral disease, it should be combined into and control with enriching yin and nourishing kidney, clearing heat and detoxicating, anti-inflammatory fall fire Chinese medicine Treatment scheme, has used and has been conducive to strengthening among body immunity, the medicine pearl powder that clears liver and improve vision, anti-inflammatory analgetic, blood activating and promoting tissue regeneration Medicine Radix Notoginseng powder, has reached obvious therapeutic effect.

Embodiment

Cataract of old people and its medicine are applied to the dose drug that an Aged-related Cataract Patients are taken It is to be combined by following each traditional Chinese medicine quality：10 grams of wintercherry fruit or calyx, 10 grams of ginseng, 12 grams of Chinese small iris, 10 grams of honeysuckle, saline cistanche 12 Gram, it is 10 grams of the root bark of tree peony, 10 grams of the fruit of Chinese wolfberry, 12 grams of the dried rhizome of rehmannia, 10 grams of the root bark of Chinese wolf-berry, 10 grams of trollflower, 8 grams of Radix Notoginseng powder, 10 grams of Semen Cuscutae, precious 3 grams of pearl powder, 10 grams of mung bean, 7 grams of Radix Glycyrrhizae.Application method：Decoct soup is taken orally, and patient with severe symptoms takes dose day, and wherein pearl powder should be straight Connect and taken after mixing it with water with boiling water or taken after mixing it with water with above-mentioned medicine soup.The dose taken can with the mitigation of the state of an illness decrement, until recovery from illness.The present invention's Cataract of old people and its medicine treatment cure rate 80%.

Claims (1)

1. cataract of old people and its medicine, it is characterized in that being combined by following each traditional Chinese medicine quality part ratio：Wintercherry fruit or calyx 10 Part, 10 parts of ginseng, Chinese small iris son 12 parts, 10 parts of honeysuckle, 12 parts of saline cistanche, 10 parts of the root bark of tree peony, 10 parts of the fruit of Chinese wolfberry, 12 parts of the dried rhizome of rehmannia, 10 parts of bone skin, 10 parts of trollflower, 8 parts of Radix Notoginseng powder, 10 parts of Semen Cuscutae, 3 parts of pearl powder, 10 parts of mung bean, 7 parts of Radix Glycyrrhizae.