CN102755549B - Drug for curing cataract and preparation method thereof - Google Patents
Drug for curing cataract and preparation method thereof Download PDFInfo
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- CN102755549B CN102755549B CN 201210255638 CN201210255638A CN102755549B CN 102755549 B CN102755549 B CN 102755549B CN 201210255638 CN201210255638 CN 201210255638 CN 201210255638 A CN201210255638 A CN 201210255638A CN 102755549 B CN102755549 B CN 102755549B
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Abstract
The invention relates to a drug for curing cataract and a preparation method of the drug. The drug comprises the following 12 Chinese medicinal plants: tribulus terrestris, lignum dalbergiae odoriferae, verbena, Indian buead, duckweed, radix codonopsitis, reed rhizome, tree peony bark, seeds of feater cockscomb, medicated leaven, pipewort and marine algae. The drug has the effects of tonifying the liver and kidney, invigorating the spleen and the stomach, nourishing the liver, improving eyesight, removing stasis, eliminating cataract, smoothing veins and regaining sight, has a better curativeeffect on patients with cataract, can be used for curing cataract at different stages, has a definite drug effect, takes effect quickly, is convenient to take, and has no toxic or side effects with the total effective rate reaching more than 93%.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of cataractous medicine and preparation method thereof for the treatment of.
Background technology
Cataract is the slow chronic ophthalmic of falling, gradually extremely losing one's sight of vision, be commonly encountered diseases and the frequently-occurring disease on the clinical ophthalmology, according to investigation, cataract is modal blinding and reason with visual disabilities, human about 25% suffers from cataract, the sickness rate of 50～60 years old senile cataract is that the old people who reaches more than 80%, 80 years old more than 60%～70%, 70 years old almost reaches 100%.Medically lenticular muddiness in the human eye cataract because the crystalline lens muddiness is opaque, the thing of seeing just thickens unclear, severe patient then be can't see the external world, patient's pupil is bleached by black, the old friend claims cataract.Its main etiology and pathogenesis is worn with age, both liver and kidney deficiency, and asthenia of essence and blood, or insufficiency of the spleen mistake fortune, vital essence can not sending nutrient upward to eye and cause.Cataractously mainly show as the initial stage and look little dusk of thing, or the where there is light looks dusk, the dark place is looked clearly, or the where there is light looks clearly, and dusk is looked in the dark place, and dim day of dusk is near, does not distinguish the personage, only sees manually, even only deposits light sensation.Along with the formation gradually of aging society, its sickness rate is more and more higher, is having a strong impact on old people's quality of life.
At present, for cataractous treatment, doctor trained in Western medicine is based on operative treatment, curative effect still can, but a plurality of complication may appear in postoperative, directly influence therapeutic effect, patient suffers misery when not only treating, and the expense costliness.The waiting time of operative treatment is longer, and 1～2 year at least, many decades can be ripe at most, just can undergo surgery when vision has only sensitization.Since exenterate most anterior capsule, whole cortex and nuclear, make crystalline lens lose the protective effect of phylloxanthin, increased various impairment factors simultaneously, so the sickness rate of after cataract is still very high.Treat cataractous Western medicine and cure the symptoms, not the disease often, though symptom is alleviated for the moment, drug effect is decorporated, and the symptom resume combustion can not tackle the problem at its root; It is also a lot of to treat cataractous Chinese medicine, but because the particularity of eyes, and the multiformity of cataract pathogenic factor, often make that Chinese medicine effect when the treatment cataract is not remarkable, can not effectively solve sufferer.
Summary of the invention
Task of the present invention provides a kind of cataractous medicine for the treatment of, and simultaneously, the present invention also provides the preparation method of the cataractous medicine of this treatment.Under the guidance of theory of Chinese medical science, by the rational proportion of each medical material, synergism has better curative effect to the treatment cataract.
Cataract belongs to the category of the traditional Chinese medical science " cataract ", refers to brilliant pearl muddiness, and vision is slow falls, Shi Ming chronic oculopathy gradually, because of finally in the middle of pupil god the circular silvery white of appearance or tan nebula buttocks hinder and gain the name.Doctor trained in Western medicine thinks that senile regression, wound, poisoning, immunity and Developmental and Metabolic Disorder, h and E factor affecting are relevant.The traditional Chinese medical science thinks then how weak with age primary disease is, both liver and kidney deficiency, and vital essence can not go up honor, due to the eyes losing nutrition.
According to above theory, in conjunction with cataractous disease, the enforcement of technical scheme of the present invention is as follows:
A kind ofly treat cataractous medicine, the raw material of making described effective ingredient forms and parts by weight are:
15～20 parts in 12～22 parts of Poria of 15～25 portions of Herba Verbenae of 15～25 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
10～20 parts of 10～20 parts of Cortex Moutans of 12～22 parts of Rhizoma Phragmitiss of 12～22 parts of Radix Codonopsis of Herba Spirodelae
2～8 parts of 3～10 portions of Sargassums of 5～15 parts of Flos Eriocaulis of 10～20 parts of Massa Medicata Fermentata of Semen Celosiae
Raw material composition and the parts by weight of making described effective ingredient are:
16～19 parts in 14～20 parts of Poria of 17～22 portions of Herba Verbenae of 17～22 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
13～18 parts of 13～18 parts of Cortex Moutans of 14～20 parts of Rhizoma Phragmitiss of 14～20 parts of Radix Codonopsis of Herba Spirodelae
4～7 parts of 5～9 portions of Sargassums of 8～12 parts of Flos Eriocaulis of 13～18 parts of Massa Medicata Fermentata of Semen Celosiae
Raw material composition and the parts by weight of making described effective ingredient are:
18 parts in 18 parts of Poria of 20 portions of Herba Verbenae of 20 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
16 parts of 16 parts of Cortex Moutans of 18 parts of Rhizoma Phragmitiss of 18 parts of Radix Codonopsis of Herba Spirodelae
5 parts of 7 portions of Sargassums of 10 parts of Flos Eriocaulis of 16 parts of Massa Medicata Fermentata of Semen Celosiae
A kind of cataractous medicine and preparation method thereof for the treatment of comprises following processing step:
(1) according to above-mentioned parts by weight, get Fructus Tribuli, Lignum Dalbergiae Odoriferae, Herba Verbenae, Poria and Herba Spirodelae mix homogeneously after, be ground into 100～120 purpose fine powders.
(2) Radix Codonopsis, Rhizoma Phragmitis, Cortex Moutan, Semen Celosiae, Massa Medicata Fermentata, Flos Eriocauli and Sargassum are decocted with water 3 times, each 1～2 hour, merge 3 times decocting liquid, be condensed into 45～50 ℃ of following relative densities and be 1.12～1.16 thick paste.
(3) fine powder that makes in the step (1) is added mix homogeneously in the thick paste that makes in the step (2), dried, adding fluidizer, antiseptic and lubricant are an amount of, granulate, during granulation is incapsulated, namely again.
Prevent the topmost approach of cataract to be, keep normal circulation of qi and blood in the body, the binocular QI and blood also can circulate unimpeded, and the muddiness of ophthalmic just can not rest on the crystalline lens.The traditional Chinese medical science is thought, takes the Chinese medicine of the logical blood stasis of blood alive, liver heat removing and eyesight improving, diuretic collateral dredging, invigorating the spleen and replenishing QI and can treat cataract.
The property of medicine of the used medicine of the present invention is as follows:
Fructus tribuli: acrid in the mouth, hardship, property is flat; Go into liver, lung meridian; Diffusing wind makes eye bright, the therapeutic method to keep the adverse QI flowing downwards, and promoting the circulation of blood, body light a surname loose, and can rise and can fall; Have suppressing the hyperactive liver and make eye bright, dispersing the stagnated live-QI to relieve the stagnation of QI, the effect of expelling wind and removing dampness; " can cure mirror approximately ": " eliminating the pathogens from the lung gas and the liver-wind that looses, except conjunctivitis, lung abscess, breast carcinoma, eczema.”
Lignum Dalbergiae Odoriferae: acrid in the mouth, temperature; Return liver, spleen channel; Promoting flow of QI and blood, pain relieving, hemostasis; Be used for epigastric pain, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge; " book on Chinese herbal medicine is new again ": " control all pathogenic factor in the exterior, the strongly fragrant gas of a surname's the five internal organs, sharp three warmers heat in blood, emesis, and taste.”
Herba Verbenae: bitter in the mouth, cold; Return liver, spleen channel; Promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, detoxifcation, inducing diuresis to remove edema; " Tian Bao book on Chinese herbal medicine ": " diuresis, suppressing the hyperactive liver pathogenic fire purging.Control red skin ulcer, acute catarrhal conjunctivitis.”
Poria: sweet in the mouth, light, property are flat; Go into the heart, lung, spleen, kidney channel; Be used as medicine have promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming, the effect such as generation, blood sugar lowering, anti-radiation with calmness and the liver protecting, inhibition ulcer." medication heart method ": " sweet with supporing yang, the panacea of dehumidifying also for Poria, the sharp key of light energy.The flat YANG invigorating of sweet in the mouth, strengthening the spleen is relieved oedema or abdominal distension through diuresis or purgation, the inducing QI of promoting the production of body fluid.”
Herba Spirodelae: acrid in the mouth, cold; Go into lung meridian; Have analgesic and bacteriostasis; Diaphoresis is dispeled the wind, row water, heat clearing away, detoxifcation.Holy Benevolent Prescriptions: " control the nose warship again, be on the point of the lake to control conjunctival congestion, aphtha, both be apt to relieve inflammation or internal heat, and heat conduction is descending, it imitates good prompt.”
Radix Codonopsis: property is flat, sweet in the mouth, little acid; Return spleen, lung meridian; Invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, supplementing QI for promoting the production of body fluid; Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst." Bencao Congxin ": " invigorating the spleen and replenishing QI and taste relieving thirst and restlessness.”
Rhizoma Phragmitis: sweet in the mouth, cold in nature; Return lung meridian, stomach warp; Clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis; " Tian Bao book on Chinese herbal medicine ": " kidney tonifying that clears away heart-fire removes the order mist, dizziness, and tinnitus, sore, night, dream was put upside down, seminal emission.”
Cortex Moutan: cold in nature, bitter in the mouth, cold is slightly cold; GUIXIN, liver, kidney, lung meridian; Clearing away heat and cooling blood, promoting blood circulation to remove blood stasis, antiinflammatory is antibacterial; Clear away heart-fire, support kidney, regulating liver-QI, sharp envelope." Bencao Jingshu ": " its gas is cold and nontoxic for Cortex Moutan, its bitter in the mouth and little suffering, and hot poly-with eliminating stagnation, bitter cold is gone into blood system except heat in blood, and the key medicine of removing heat from blood heat also.”
Semen Celosiae: cold nature, bitter in the mouth; Return Liver Channel; Liver heat removing makes eye bright, nebula removing.Be used for liver-heat conjunctival congestion, the nebula of looking unfamiliar film, blurring of vision, dizziness due to liver-fire; Have and let out liver-fire clearly, the function of improving acuity of vision and removing nebula;
Massa Medicata Fermentata: property slightly sweet flavor, delicate fragrance; Go into spleen, stomach, large intestine channel; Strengthening the spleen to promote digestion, regulating QI to expel dampness induces sweat;
" detailed outline ": " by Ni Weide (Qi Weiji) cloud: Massa Medicata Fermentata is controlled the order disease, gives birth to sending out its anger, and is hot with holding back its sudden and violent gas also.”
Flos Eriocauli: property acrid-sweet flavor, cold; Go into liver, stomach warp; Wind and heat eliminating, improving acuity of vision and removing nebula; Control corneal nebula, night blindness is used for the wind heat conjunctival congestion, the photophobia that swells and ache, the nebula of looking unfamiliar film; " detailed outline ": " control the wind syndrome of head pain, blindness nebula film is given birth to nebula, hemostasis after the pox.”
Sargassum: cold in nature, salty in the mouth, hardship are returned lung, spleen, kidney, liver stomach warp; Softening the hard mass, expectorant, diuretic, detumescent; " book on Chinese herbal medicine is just read ": " the capable water of softening the hard mass is its this merit for Sargassum, the product of salty-cold relaxing the bowels with lubricant drugs, thus the card of all scrofula goiter pertinacious phlegm gluings, all available it.”
The present invention compared with prior art has following beneficial effect:
1, the present invention has better curative effect with 12 flavor Chinese medicine science compatibilities to cataract, can be used for the cataractous treatment of different times, is applicable to the crowd of different body constitution; Can improve the physiological function of human body, can accelerate the circulation of anterior ocular segment blood fortune and Nutrition and Metabolism, improve capsulociliary permeability, recover its physiologic barrier effect, effectively control the crystalline lens muddiness, promote muddy the absorption.
2, synergism between each raw material of the present invention, all medicine compatibilities, bring out the best in each other, play the merit that liver and kidney tonifying, invigorating spleen and nourishing heart, promoting flow of QI and blood, liver heat removing and eyesight improving, blood stasis dispelling move back barrier altogether, effect is remarkable, drug effect is definite, short treating period, instant effect has no side effect, more the back is difficult for recurrence, and total effective rate reaches more than 93%.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention is formed and parts by weight are:
15～20 parts in 12～22 parts of Poria of 15～25 portions of Herba Verbenae of 15～25 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
10～20 parts of 10～20 parts of Cortex Moutans of 12～22 parts of Rhizoma Phragmitiss of 12～22 parts of Radix Codonopsis of Herba Spirodelae
2～8 parts of 3～10 portions of Sargassums of 5～15 parts of Flos Eriocaulis of 10～20 parts of Massa Medicata Fermentata of Semen Celosiae
The processing step of said medicine preparation method of the present invention is:
(1) according to above-mentioned parts by weight, get Fructus Tribuli, Lignum Dalbergiae Odoriferae, Herba Verbenae, Poria and Herba Spirodelae mix homogeneously after, be ground into 100～120 purpose fine powders.
(2) Radix Codonopsis, Rhizoma Phragmitis, Cortex Moutan, Semen Celosiae, Massa Medicata Fermentata, Flos Eriocauli and Sargassum are decocted with water 3 times, each 1～2 hour, merge 3 times decocting liquid, be condensed into 45～50 ℃ of following relative densities and be 1.12～1.16 thick paste.
(3) fine powder that makes in the step (1) is added mix homogeneously in the thick paste that makes in the step (2), dried, adding fluidizer, antiseptic and lubricant are an amount of, granulate, during granulation is incapsulated, namely again.
Embodiment 2
The raw material of effective ingredient of the present invention is formed and parts by weight are:
16～19 parts in 14～20 parts of Poria of 17～22 portions of Herba Verbenae of 17～22 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
13～18 parts of 13～18 parts of Cortex Moutans of 14～20 parts of Rhizoma Phragmitiss of 14～20 parts of Radix Codonopsis of Herba Spirodelae
4～7 parts of 5～9 portions of Sargassums of 8～12 parts of Flos Eriocaulis of 13～18 parts of Massa Medicata Fermentata of Semen Celosiae
The process for preparing medicine processing step of present embodiment is identical with embodiment 1.
Embodiment 3
The raw material of effective ingredient of the present invention is formed and parts by weight are:
18 parts in 18 parts of Poria of 20 portions of Herba Verbenae of 20 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
16 parts of 16 parts of Cortex Moutans of 18 parts of Rhizoma Phragmitiss of 18 parts of Radix Codonopsis of Herba Spirodelae
5 parts of 7 portions of Sargassums of 10 parts of Flos Eriocaulis of 16 parts of Massa Medicata Fermentata of Semen Celosiae
The process for preparing medicine processing step of present embodiment is identical with embodiment 1.
Clinical data:
1, case is selected
As the cataractous medicine for the treatment of, select the cataract patient 264 routine clinical observations make a definite diagnosis, male's 145 examples wherein, women's 119 examples, 42～78 years old age, 58.4 years old mean age, the course of disease 2～8 years, average 5 years.All patients all have visual disorder in various degree, get rid of to merge other eye part diseases, as glaucoma, retinopathy, high myopia etc.
2, take medicine of the present invention, oral 3 times of every day of adult, each 2 capsules, 30 days courses for the treatment of, continuous three courses for the treatment of.
3, efficacy determination:
(1) produce effects: vision improves significantly or improves more than 4 row, transference cures such as blurred vision, and the examination with slitlamp microscope lenticular opacity obviously alleviates;
(2) effective: vision improves more than 2 row, big disappearance of symptoms such as blurred vision, and the examination with slitlamp microscope lenticular opacity alleviates;
(3) improve: vision improves more than 1 row, and symptoms such as blurred vision take a turn for the better, and the examination with slitlamp microscope lenticular opacity has slightly and alleviates;
(4) invalid: vision does not have raising, and symptoms such as blurred vision do not have improvement or increase the weight of, and examination with slitlamp microscope lenticular opacity thing does not have change or muddiness increases the weight of.
4, result
Take medicine of the present invention after three courses for the treatment of, produce effects 145 examples, effective 62 examples are improved 39 examples, invalid 18 examples, total effective rate 93.2%.
In the clinical observation process, curative effect of medication is definite, does not find that the patient has untoward reaction and anaphylaxis, illustrates that this product is safe and effective.
Claims (4)
1. treat cataractous medicine for one kind, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
15～20 parts in 12～22 parts of Poria of 15～25 portions of Herba Verbenae of 15～25 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
10～20 parts of 10～20 parts of Cortex Moutans of 12～22 parts of Rhizoma Phragmitiss of 12～22 parts of Radix Codonopsis of Herba Spirodelae
2～8 parts of 3～10 portions of Sargassums of 5～15 parts of Flos Eriocaulis of 10～20 parts of Massa Medicata Fermentata of Semen Celosiae.
2. a kind of cataractous medicine for the treatment of according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
16～19 parts in 14～20 parts of Poria of 17～22 portions of Herba Verbenae of 17～22 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
13～18 parts of 13～18 parts of Cortex Moutans of 14～20 parts of Rhizoma Phragmitiss of 14～20 parts of Radix Codonopsis of Herba Spirodelae
4～7 parts of 5～9 portions of Sargassums of 8～12 parts of Flos Eriocaulis of 13～18 parts of Massa Medicata Fermentata of Semen Celosiae.
3. a kind of cataractous medicine for the treatment of according to claim 1 is characterized in that: the raw material of making described effective ingredient forms and parts by weight are:
18 parts in 18 parts of Poria of 20 portions of Herba Verbenae of 20 parts of Lignum Dalbergiae Odoriferaes of Fructus Tribuli
16 parts of 16 parts of Cortex Moutans of 18 parts of Rhizoma Phragmitiss of 18 parts of Radix Codonopsis of Herba Spirodelae
5 parts of 7 portions of Sargassums of 10 parts of Flos Eriocaulis of 16 parts of Massa Medicata Fermentata of Semen Celosiae.
4. preparation method as claim 1-3 cataractous medicine for the treatment of as described in each is characterized in that: comprise following processing step:
(1) according to above-mentioned parts by weight, get Fructus Tribuli, Lignum Dalbergiae Odoriferae, Herba Verbenae, Poria and Herba Spirodelae mix homogeneously after, be ground into 100～120 purpose fine powders;
(2) Radix Codonopsis, Rhizoma Phragmitis, Cortex Moutan, Semen Celosiae, Massa Medicata Fermentata, Flos Eriocauli and Sargassum are decocted with water 3 times, each 1～2 hour, merge 3 times decocting liquid, be condensed into 45～50 ℃ of following relative densities and be 1.12～1.16 thick paste;
(3) fine powder that makes in the step (1) is added mix homogeneously in the thick paste that makes in the step (2), dried, adding fluidizer, antiseptic and lubricant are an amount of, granulate, during granulation is incapsulated, namely again.
Priority Applications (1)
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| CN 201210255638 CN102755549B (en) | 2012-07-16 | 2012-07-16 | Drug for curing cataract and preparation method thereof |
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| CN 201210255638 CN102755549B (en) | 2012-07-16 | 2012-07-16 | Drug for curing cataract and preparation method thereof |
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| CN102755549B true CN102755549B (en) | 2013-09-25 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104815088A (en) * | 2015-05-12 | 2015-08-05 | 苏州谷力生物科技有限公司 | Eyedrops for treating cataract and preparation method of eyedrops |
| CN105434721A (en) * | 2015-12-28 | 2016-03-30 | 青岛大学附属医院 | Drug for preventing and delaying incipient age-related cataract |
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