CN104856679B - 用于哮喘、肺结核及肺癌诊断及疾病管控的呼吸分析系统及方法 - Google Patents

用于哮喘、肺结核及肺癌诊断及疾病管控的呼吸分析系统及方法 Download PDF

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Publication number
CN104856679B
CN104856679B CN201510181153.5A CN201510181153A CN104856679B CN 104856679 B CN104856679 B CN 104856679B CN 201510181153 A CN201510181153 A CN 201510181153A CN 104856679 B CN104856679 B CN 104856679B
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individual
ambient air
asthma
volatile organic
breath
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CN104856679A (zh
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王利鹏
杨志林
黄简林
曾关·A·周
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Creation And Control Of Polytron Technologies Inc
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TRICORNTECH CORP
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/097—Devices for facilitating collection of breath or for directing breath into or through measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/028—Microscale sensors, e.g. electromechanical sensors [MEMS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/025—Gas chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • G01N33/4975—Physical analysis of biological material of gaseous biological material, e.g. breath other than oxygen, carbon dioxide or alcohol, e.g. organic vapours

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CN201510181153.5A 2008-12-01 2009-11-30 用于哮喘、肺结核及肺癌诊断及疾病管控的呼吸分析系统及方法 Active CN104856679B (zh)

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US11897708P 2008-12-01 2008-12-01
US61/118,977 2008-12-01
CN2009801558120A CN102300502A (zh) 2008-12-01 2009-11-30 用于哮喘、肺结核及肺癌诊断及疾病管控的呼吸分析系统及方法

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CN104856679B true CN104856679B (zh) 2019-02-22

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CN2009801558120A Pending CN102300502A (zh) 2008-12-01 2009-11-30 用于哮喘、肺结核及肺癌诊断及疾病管控的呼吸分析系统及方法

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US (2) US10568541B2 (https=)
EP (1) EP2369989A4 (https=)
JP (1) JP5848608B2 (https=)
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Families Citing this family (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2858236B1 (fr) 2003-07-29 2006-04-28 Airox Dispositif et procede de fourniture de gaz respiratoire en pression ou en volume
US8302602B2 (en) 2008-09-30 2012-11-06 Nellcor Puritan Bennett Llc Breathing assistance system with multiple pressure sensors
CN104856679B (zh) 2008-12-01 2019-02-22 创控科技股份有限公司 用于哮喘、肺结核及肺癌诊断及疾病管控的呼吸分析系统及方法
US8434479B2 (en) 2009-02-27 2013-05-07 Covidien Lp Flow rate compensation for transient thermal response of hot-wire anemometers
US8439037B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integrated filter and flow sensor
US8469030B2 (en) * 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with selectable contagious/non-contagious latch
US8439036B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integral flow sensor
US8469031B2 (en) 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with integrated filter
WO2012023138A2 (en) 2010-08-18 2012-02-23 Technion Research And Development Foundation Ltd. Volatile organic compounds for detecting cell dysplasia and genetic alterations associated with lung cancer
GB201018692D0 (en) * 2010-11-05 2010-12-22 Univ Manchester Biomarkers
US9629971B2 (en) 2011-04-29 2017-04-25 Covidien Lp Methods and systems for exhalation control and trajectory optimization
RU2466730C1 (ru) * 2011-11-09 2012-11-20 Государственное бюджетное образовательное учреждение высшего профессионального образования "Омская государственная медицинская академия" Министерства здравоохранения и социального развития Российской Федерации (ГБОУ ВПО ОмГМА Минздравсоцразвития России) Способ подготовки к пробе манту с 2 те ппд-л у детей с отягощенным аллергическим анамнезом
US9528979B2 (en) 2011-11-15 2016-12-27 Technion Research And Development Foundation Ltd. Breath analysis of pulmonary nodules
US9364624B2 (en) 2011-12-07 2016-06-14 Covidien Lp Methods and systems for adaptive base flow
US9498589B2 (en) 2011-12-31 2016-11-22 Covidien Lp Methods and systems for adaptive base flow and leak compensation
TWI458464B (zh) * 2012-02-01 2014-11-01 Nat Univ Tsing Hua 可早期偵測及辨識肺炎種類之呼吸器、其氣體辨識晶片、及其氣體辨識方法
US9770192B2 (en) * 2012-03-19 2017-09-26 Richard C. Fuisz Method and system to amplify and measure breath analytes
US9144658B2 (en) 2012-04-30 2015-09-29 Covidien Lp Minimizing imposed expiratory resistance of mechanical ventilator by optimizing exhalation valve control
US9164080B2 (en) 2012-06-11 2015-10-20 Ohio State Innovation Foundation System and method for sensing NO
US8974734B2 (en) 2012-07-20 2015-03-10 Eps Bio Technology Corp. Electronic nose device
JP2014023603A (ja) * 2012-07-25 2014-02-06 Nippon Koden Corp 睡眠時無呼吸判定装置
IN2015DN04092A (https=) * 2012-10-29 2015-10-09 Technion Res & Dev Foundation
JP6159821B2 (ja) * 2012-12-26 2017-07-05 アール バイオ カンパニー リミテッドＲ Ｂｉｏ Ｃｏ．， Ｌｔｄ． 呼吸ガスを利用した癌の診断方法
USD731049S1 (en) 2013-03-05 2015-06-02 Covidien Lp EVQ housing of an exhalation module
USD731065S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ pressure sensor filter of an exhalation module
USD692556S1 (en) 2013-03-08 2013-10-29 Covidien Lp Expiratory filter body of an exhalation module
USD701601S1 (en) 2013-03-08 2014-03-25 Covidien Lp Condensate vial of an exhalation module
USD744095S1 (en) 2013-03-08 2015-11-24 Covidien Lp Exhalation module EVQ internal flow sensor
USD693001S1 (en) 2013-03-08 2013-11-05 Covidien Lp Neonate expiratory filter assembly of an exhalation module
USD736905S1 (en) 2013-03-08 2015-08-18 Covidien Lp Exhalation module EVQ housing
USD731048S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ diaphragm of an exhalation module
US9950135B2 (en) 2013-03-15 2018-04-24 Covidien Lp Maintaining an exhalation valve sensor assembly
JP6182796B2 (ja) * 2013-06-28 2017-08-23 国立研究開発法人産業技術総合研究所 呼気分析システム、肺がんマーカー及び呼気分析方法
AU2014312293B2 (en) * 2013-08-28 2020-04-30 University Of Louisville Research Foundation, Inc. Noninvasive detection of lung cancer using exhaled breath
KR101489093B1 (ko) * 2013-11-06 2015-02-06 경희대학교 산학협력단 호흡 훈련 장치 및 방법
BR112016018896B1 (pt) * 2014-02-19 2022-10-04 Koninklijke Philips N.V. Sistema para fornecer uma indicação de síndrome de desconforto respiratório agudo de um paciente
US10307080B2 (en) 2014-03-07 2019-06-04 Spirosure, Inc. Respiratory monitor
JP6256986B2 (ja) * 2014-03-28 2018-01-10 学校法人順天堂 食道癌の判定方法
US9011779B1 (en) 2014-05-21 2015-04-21 Andas Inc. Device for measurement of exhaled ethanol concentration
US9366664B2 (en) 2014-05-21 2016-06-14 Andas Inc. Device for measurement of exhaled nitric oxide concentration
DE102014210574A1 (de) * 2014-06-04 2015-12-17 Robert Bosch Gmbh Messvorrichtung und Verfahren zur Bestimmung der asthmatisch wirksamen Belastung bei einem Menschen oder Tier
CN106796217A (zh) * 2014-07-21 2017-05-31 泰克年研究发展基金会公司 用于直接呼吸采样的组合物
US11262354B2 (en) 2014-10-20 2022-03-01 Boston Scientific Scimed, Inc. Disposable sensor elements, systems, and related methods
GB201502447D0 (en) * 2015-02-13 2015-04-01 Univ Liverpool Method and apparatus for sample analysis
CN106137204A (zh) * 2015-04-02 2016-11-23 中国科学院生态环境研究中心 利用真空紫外光电离质谱仪进行肺癌早期筛查的方法
USD775345S1 (en) 2015-04-10 2016-12-27 Covidien Lp Ventilator console
KR101813553B1 (ko) * 2015-05-20 2017-12-29 박종복 호기 가스 성분을 이용한 비접촉식 스위치
CN104970775A (zh) * 2015-07-01 2015-10-14 深圳市前海安测信息技术有限公司 肺结核病早期症状监测方法及监测系统
US20170059554A1 (en) * 2015-09-02 2017-03-02 R. J. Reynolds Tobacco Company Method for monitoring use of a tobacco product
EP3143930A1 (en) * 2015-09-21 2017-03-22 Université de Liège Method for the diagnosis of airway disease inflammatory subtype
EP3397156A1 (en) * 2015-12-31 2018-11-07 The Cleveland Clinic Foundation Method, computing device and system for collecting exhaled breath
US11389062B2 (en) 2016-03-01 2022-07-19 Koninklijke Philips N.V. System and method for determining a risk level of a respiratory attack
EP3452150B1 (en) * 2016-05-03 2024-01-17 Pneuma Respiratory, Inc. Droplet delivery device for delivery of fluids to the pulmonary system
WO2017192782A1 (en) * 2016-05-03 2017-11-09 Pneuma Respiratory, Inc. Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment
ES2979317T3 (es) 2016-06-15 2024-09-25 Univ Minnesota Catéteres de muestreo de gas
CN106361343A (zh) * 2016-08-31 2017-02-01 王未来 一种智能峰流速仪及管控使用方法
US11172846B2 (en) 2016-10-21 2021-11-16 Boston Scientific Scimed, Inc. Gas sampling device
CN106422744B (zh) * 2016-11-09 2023-03-14 暨南大学 一次性手术烟雾净化器
JP2020510831A (ja) 2017-03-01 2020-04-09 日本特殊陶業株式会社 還元ガスを用いた一酸化窒素検出装置
JP6879545B2 (ja) * 2017-03-15 2021-06-02 株式会社タニタ 生体ガス検知装置、方法、及びプログラム
WO2018173060A1 (en) 2017-03-23 2018-09-27 Technion Research & Development Foundation Ltd. Device and methods for detection and monitoring of tuberculosis
US10770182B2 (en) 2017-05-19 2020-09-08 Boston Scientific Scimed, Inc. Systems and methods for assessing the health status of a patient
WO2018213834A1 (en) 2017-05-19 2018-11-22 Pneuma Respiratory, Inc. Dry powder delivery device and methods of use
US10852264B2 (en) 2017-07-18 2020-12-01 Boston Scientific Scimed, Inc. Systems and methods for analyte sensing in physiological gas samples
CN111526914A (zh) 2017-10-04 2020-08-11 精呼吸股份有限公司 电子呼吸致动式直线型液滴输送装置及其使用方法
EP4344719B1 (en) 2017-10-17 2025-12-31 Pneuma Respiratory, Inc. NASAL MEDICATION ADMINISTRATION DEVICE
JP2021502178A (ja) 2017-11-08 2021-01-28 ニューマ・リスパイラトリー・インコーポレイテッド 小容積アンプルを有して呼吸により電気的に作動するインライン液滴送達装置および使用方法
WO2019164925A1 (en) * 2018-02-20 2019-08-29 Regents Of The University Of Minnesota Breath sampling mask and system
DE102018114970A1 (de) * 2018-06-21 2019-12-24 breazy-health GmbH System und Verfahren zur Bereitstellung von zumindest einer Information über zumindest eine Wechselwirkung zwischen Umgebungsluft und Atemfunktion von einem Individuum
WO2020049438A2 (en) * 2018-09-03 2020-03-12 Kozhnosys Private Limited System for detection of volatile organic compounds (voc) in exhaled breath for health monitoring
EP3860457A1 (en) * 2018-10-06 2021-08-11 The Cleveland Clinic Foundation Method for diagnosing clostridioides difficile infection
CN112930480A (zh) 2018-10-19 2021-06-08 明尼苏达大学董事会 用于检测脑病症的系统和方法
WO2020112027A1 (en) * 2018-11-28 2020-06-04 National University Of Singapore Method of detecting cancer and/or tuberculosis
CN113167758A (zh) 2018-11-27 2021-07-23 波士顿科学国际有限公司 用于检测健康状况的系统和方法
WO2020131567A1 (en) 2018-12-18 2020-06-25 Boston Scientific Scimed, Inc. Systems and methods for measuring kinetic response of chemical sensor elements
EP3962358A1 (en) 2019-04-29 2022-03-09 Regents of the University of Minnesota Systems and methods for assessing and treating hemorrhage and other conditions
KR102901714B1 (ko) 2019-05-20 2026-01-08 숙명여자대학교산학협력단 비색 센서 어레이 및 이의 제조방법
CN110179467B (zh) * 2019-05-29 2023-11-14 中国医学科学院生物医学工程研究所 一种用于肺癌诊断的呼吸采样装置
EP4013302A1 (en) 2019-08-13 2022-06-22 Respiration Scan Ltd System and method for determining onset and disease progression
JP7411281B2 (ja) 2019-08-26 2024-01-11 ゼテオ テック、 インク． 呼気関連アプリケーションを使用した結核およびその他の疾患の診断
EP4028758A2 (en) 2019-09-10 2022-07-20 Boston Scientific Scimed Inc. Gas measurement device and method
GB201914183D0 (en) * 2019-10-01 2019-11-13 Owlstone Med Ltd Biomarker
CN110755056A (zh) * 2019-11-21 2020-02-07 中国中医科学院 医生四诊过程记录仪
US11054347B1 (en) * 2019-12-31 2021-07-06 X Development Llc Enhanced gas sensor selectivity
BR102020002883A2 (pt) * 2020-02-11 2021-08-24 Nathalia Moraes Do Nascimento Método para identificação e monitoramento de doenças a partir de amostras de gases captadas por um dispositivo e método de treinamento de uma rede neural para identificação de doenças a partir de amostras de gases captadas por um dispositivo
US11896767B2 (en) 2020-03-20 2024-02-13 Covidien Lp Model-driven system integration in medical ventilators
KR102746174B1 (ko) 2020-04-03 2024-12-23 제테오 테크, 인코포레이티드 호기 및 에어로졸 분석을 이용한 호흡기 질환 진단
US12364411B2 (en) 2020-04-03 2025-07-22 Zeteo Tech, Inc. Diagnosis of respiratory diseases using analysis of exhaled breath and aerosols
WO2021256460A1 (ja) * 2020-06-17 2021-12-23 株式会社レボーン システム、情報処理装置及びプログラム
JP7645454B2 (ja) * 2020-06-29 2025-03-14 パナソニックＩｐマネジメント株式会社 ガスセンサ
CN111784683B (zh) * 2020-07-10 2022-05-17 天津大学 病理切片检测方法及装置、计算机设备及存储介质
IT202000032249A1 (it) * 2020-12-23 2022-06-23 Eurotech Spa Apparato di identificazione di stati patologici e relativo metodo
EP4312749A4 (en) 2021-03-31 2025-07-09 Zeteo Tech Inc DIAGNOSIS OF RESPIRATORY DISEASES BY CAPTURE OF AEROSOLIZED BIOMATERIAL PARTICLES USING FIXED BED SYSTEMS AND METHODS
US12480907B2 (en) 2021-04-16 2025-11-25 Regents Of The University Of Minnesota Systems utilizing graphene varactor hysteresis effects for sample characterization
US11793945B2 (en) 2021-06-22 2023-10-24 Pneuma Respiratory, Inc. Droplet delivery device with push ejection
EP4119046A1 (en) 2021-07-13 2023-01-18 Universitäts-kinderspital Beider Basel Method for processing mass spectrometry data obtained from breath gas
CN113588821A (zh) * 2021-07-29 2021-11-02 中国科学院合肥物质科学研究院 一种用于口腔气味检测识别的方法
CN114431854A (zh) * 2021-12-23 2022-05-06 新绎健康科技有限公司 基于呼吸气的数字闻诊检测装置及其检测方法
CN114720542B (zh) * 2022-03-30 2025-08-05 北京大学人民医院 基于hppi-tofms的早期肺癌诊断呼出气标志物筛选及其应用
CN119768202A (zh) 2022-07-18 2025-04-04 精呼吸股份有限公司 小步长高分辨率气溶胶生成系统及方法
US20240264145A1 (en) * 2023-02-07 2024-08-08 Aleck Alexopoulos Device, method, and system for the rapid detection of the tuberculosis mycobacterium dispersed in air
KR102817329B1 (ko) * 2023-02-08 2025-06-05 재단법인 대구경북첨단의료산업진흥재단 호기 가스 분석을 통한 폐질환 진단 시스템 및 이의 제어 방법
EP4666941A1 (en) 2023-02-16 2025-12-24 Gustavo Senna Chelles Exhaled air sample collector for pre-diagnosis of pathologies, and method for using same
TR2023012870A2 (tr) * 2023-10-11 2023-10-23 Kmue Strateji Gelistirme Dairesi Baskanligi Elektroni̇k burun kullanilarak ki̇şi̇ni̇n nefes bi̇lgi̇si̇nden psori̇asi̇s (sedef) hastaliği teşhi̇s si̇stemi̇ ve metodu
WO2025117806A1 (en) * 2023-11-30 2025-06-05 Arizona Board Of Regents On Behalf Of Arizona State University Volatile biomarkers for discriminating valley fever from other lung infections
WO2026033218A1 (en) * 2024-08-06 2026-02-12 Breath Predict Limited System and method for predicting asthma exacerbations

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4869876A (en) * 1984-04-30 1989-09-26 International Business Machines Corp. Multi-purpose plural-oven gas chromatography system with shared controls
US4888295A (en) * 1984-03-02 1989-12-19 The United States Of America As Represented By The United States Department Of Energy Portable system and method combining chromatography and array of electrochemical sensors
CN1954208A (zh) * 2004-05-17 2007-04-25 弗门尼舍有限公司 新型多维气相色谱装置及使用多个冷却线连接件的分析物输送方法
US7343779B1 (en) * 2005-12-05 2008-03-18 Yu Conrad M High performance, hand-held gas chromatograph, method and system

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6378943A (ja) 1986-09-19 1988-04-09 鹿島建設株式会社 スラブの構築方法
US4796639A (en) * 1987-11-05 1989-01-10 Medical Graphics Corporation Pulmonary diagnostic system
JPH06764Y2 (ja) 1987-11-17 1994-01-05 フィガロ技研株式会社 ガス検出装置
FI82367C (fi) * 1988-02-11 1991-03-11 Instrumentarium Oy Till intubationsroer kopplad spirometer och provtagningsfoerbindning i gasanalysator.
US4850371A (en) 1988-06-13 1989-07-25 Broadhurst John H Novel endotracheal tube and mass spectrometer
US5081871A (en) * 1989-02-02 1992-01-21 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Breath sampler
JPH0647047A (ja) * 1992-06-03 1994-02-22 Hideo Ueda 臨床用呼気検査方法及び装置
CA2097363A1 (en) 1992-06-03 1993-12-04 Hideo Ueda Expired air examination device and method for clinical purpose
JP3838671B2 (ja) * 1993-10-25 2006-10-25 アークレイ株式会社 呼気採取装置
JPH07184488A (ja) 1993-12-24 1995-07-25 Kyowa Kk 養液栽培システム
US5465728A (en) 1994-01-11 1995-11-14 Phillips; Michael Breath collection
AU719940B2 (en) * 1996-04-09 2000-05-18 Aerocrine Ab Method and apparatus for the measurement of components of exhaled breath in humans
US5996586A (en) * 1997-03-26 1999-12-07 Phillips; Michael Breath test for detection of lung cancer
SE9801532D0 (sv) 1998-04-30 1998-04-30 Aerocrine Ab Device for the collection of exhaled air samples
WO1999065386A1 (en) * 1998-06-15 1999-12-23 The Trustees Of The University Of Pennsylvania Diagnosing intrapulmonary infection and analyzing nasal sample
WO1999066304A1 (en) * 1998-06-19 1999-12-23 California Institute Of Technology Trace level detection of analytes using artificial olfactometry
WO2000020852A1 (en) 1998-10-02 2000-04-13 California Institute Of Technology Conductive organic sensors, arrays and methods of use
GB9825904D0 (en) 1998-11-27 1999-01-20 Univ Cranfield Diagnosis of gastric and lung disorders
US6468222B1 (en) * 1999-08-02 2002-10-22 Healthetech, Inc. Metabolic calorimeter employing respiratory gas analysis
US20030208133A1 (en) * 2000-06-07 2003-11-06 Mault James R Breath ketone analyzer
US6981947B2 (en) 2002-01-22 2006-01-03 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring respiratory gases during anesthesia
US7076371B2 (en) * 2001-03-03 2006-07-11 Chi Yung Fu Non-invasive diagnostic and monitoring method and apparatus based on odor detection
US20100248268A1 (en) 2001-03-27 2010-09-30 Woods Daniel F Methods to utilize invertebrate chemosensory proteins for industrial and commercial uses
AU2002309803A1 (en) * 2001-04-17 2002-10-28 University Of Virginia Patent Foundation Breath test for assessing diseases, particularly asthma
DE10121262A1 (de) * 2001-04-30 2002-11-14 Siemens Ag Vorrichtung zur quantitativen Messung von Stickoxiden in der Ausatemluft und Verwendung
US20030023181A1 (en) * 2001-07-26 2003-01-30 Mault James R. Gas analyzer of the fluorescent-film type particularly useful for respiratory analysis
US6726637B2 (en) 2001-12-06 2004-04-27 Michael Phillips Breath collection apparatus
US7473229B2 (en) * 2001-12-10 2009-01-06 Pranalytica, Inc. Method of analyzing components of alveolar breath
US7153272B2 (en) * 2002-01-29 2006-12-26 Nanotherapeutics, Inc. Methods of collecting and analyzing human breath
JP2005519291A (ja) * 2002-03-04 2005-06-30 シラノ サイエンシズ インコーポレイテッド 人工的嗅覚検査による医学疾患または病気の検知、診断、およびモニタリング
US7101340B1 (en) * 2002-04-12 2006-09-05 Braun Charles L Spectroscopic breath profile analysis device and uses thereof for facilitating diagnosis of medical conditions
CN1681435B (zh) * 2002-09-16 2011-06-08 艾罗克林有限公司 用于诊断气体分析的设备和方法
US20050150778A1 (en) * 2002-11-18 2005-07-14 Lewis Nathan S. Use of basic polymers in carbon black composite vapor detectors to obtain enhanced sensitivity and classification performance for volatile fatty acids
EP1627223A1 (en) * 2003-04-01 2006-02-22 The Charles Stark Draper Laboratory, INC. Non-invasive breath analysis using field asymmetric ion mobility spectrometry
US7172557B1 (en) * 2003-08-29 2007-02-06 Caldyne, Inc. Spirometer, display and method
WO2006046588A1 (ja) 2004-10-28 2006-05-04 Seems Inc. 疾病診断システム
US7421882B2 (en) * 2004-12-17 2008-09-09 University Of Iowa Research Foundation Breath-based sensors for non-invasive molecular detection
CA2601080A1 (en) 2005-01-10 2006-07-20 David A. Edwards Method and device for decreasing contamination
JP5075638B2 (ja) 2005-01-10 2012-11-21 プルマトリックス，インコーポレイティッド 汚染を減少させるための方法及び装置
US7695681B2 (en) * 2005-03-31 2010-04-13 Intel Corporation Miniature chemical analysis system
US8117896B2 (en) * 2006-08-09 2012-02-21 Seacoast Science, Inc. Preconcentrators and methods of making and using the same
WO2008126519A1 (ja) 2007-03-22 2008-10-23 Shinshu University センサー
US20080275355A1 (en) * 2007-05-04 2008-11-06 Ekips Technologies, Inc. Method For Diagnosing An Infectioin Condition
AU2008284273A1 (en) * 2007-08-08 2009-02-12 Kemeta, Llc Biosensor system with a multifunctional portable electronic device
US9521963B2 (en) * 2008-05-13 2016-12-20 Ric Investments, Llc Respiratory component measurement system with indicating elements
US8087283B2 (en) 2008-06-17 2012-01-03 Tricorntech Corporation Handheld gas analysis systems for point-of-care medical applications
JP5289837B2 (ja) * 2008-06-30 2013-09-11 日本光電工業株式会社 生体由来ガス成分分析装置及び疾病判定支援装置
US8652064B2 (en) * 2008-09-30 2014-02-18 Covidien Lp Sampling circuit for measuring analytes
CN104856679B (zh) * 2008-12-01 2019-02-22 创控科技股份有限公司 用于哮喘、肺结核及肺癌诊断及疾病管控的呼吸分析系统及方法
US8716655B2 (en) * 2009-07-02 2014-05-06 Tricorntech Corporation Integrated ion separation spectrometer
US8999245B2 (en) * 2009-07-07 2015-04-07 Tricorn Tech Corporation Cascaded gas chromatographs (CGCs) with individual temperature control and gas analysis systems using same
US8707760B2 (en) * 2009-07-31 2014-04-29 Tricorntech Corporation Gas collection and analysis system with front-end and back-end pre-concentrators and moisture removal
US8978444B2 (en) * 2010-04-23 2015-03-17 Tricorn Tech Corporation Gas analyte spectrum sharpening and separation with multi-dimensional micro-GC for gas chromatography analysis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888295A (en) * 1984-03-02 1989-12-19 The United States Of America As Represented By The United States Department Of Energy Portable system and method combining chromatography and array of electrochemical sensors
US4869876A (en) * 1984-04-30 1989-09-26 International Business Machines Corp. Multi-purpose plural-oven gas chromatography system with shared controls
CN1954208A (zh) * 2004-05-17 2007-04-25 弗门尼舍有限公司 新型多维气相色谱装置及使用多个冷却线连接件的分析物输送方法
US7343779B1 (en) * 2005-12-05 2008-03-18 Yu Conrad M High performance, hand-held gas chromatograph, method and system

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