CN104839486A - Pelteobagrus fulvidraco feed additive with liver protection function and application thereof - Google Patents

Pelteobagrus fulvidraco feed additive with liver protection function and application thereof Download PDF

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Publication number
CN104839486A
CN104839486A CN201510251708.9A CN201510251708A CN104839486A CN 104839486 A CN104839486 A CN 104839486A CN 201510251708 A CN201510251708 A CN 201510251708A CN 104839486 A CN104839486 A CN 104839486A
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parts
yellow
feed additive
liver
pelteobagrus fulvidraco
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CN201510251708.9A
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Chinese (zh)
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黎明
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Ningbo University
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Ningbo University
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Abstract

The invention discloses a pelteobagrus fulvidraco feed additive with a liver protection function and application of the pelteobagrus fulvidraco feed additive. The pelteobagrus fulvidraco feed additive is characterized by comprising active ingredients in parts by weight:15 to 25 parts of penthorum chinense, 10 to 30 parts of rhizoma alismatis, 10 to 30 parts of cortex moutan, 5 to 15 parts of garlic, 10 to 20 parts of hawthorns and 10 to 20 parts of barbary wolfberry fruits. The pelteobagrus fulvidraco feed additive can be added into the feed according to the dosage being 5 to 10 percent. The pelteobagrus fulvidraco feed additive has the advantages that the liver health of the pelteobagrus fulvidraco can be protected, the fatty liver can be prevented and treated, the fat deposition in the liver and the abdominal cavity can be reduced, and the food intake, the body weight and the survival rate can be improved.

Description

A kind of yellow-head catfish feed additive and application thereof with liver protecting effect
Technical field
The present invention relates to a kind of yellow-head catfish feed additive, especially relate to a kind of yellow-head catfish feed additive and the application thereof with liver protecting effect.
Background technology
Pelteobagrus fulvidraco ( pelteobagrus fulvidraco) be the important economic cultured fishes of China, for omnivorous partially carnivorous, distribute in China the Changjiang river and Pearl River Delta natural water comparatively extensive, the multiple essential amino acid containing needed by human body in its muscle, especially the advantage of stinging between flesh is not had, dark liking by the general common people.According to the AUTHORITATIVE DATA that " 2013 China Fisheries statistical yearbook " is issued, ended for the end of the year 2012, national Pelteobagrus fulvidraco output reaches 260,000 tons, and year, amplification was more than 18 %, has already become one of important freshwater aquiculture kind of China.But often there will be nutritional fatty liver symptom in Pelteobagrus fulvidraco breeding process, cause Pelteobagrus fulvidraco to ingest decline, poor growth, feed coefficient raises, and belly expands, and anti-stress ability declines.Especially in summer, nutritional fatty liver easily causes explosive dead.Separate the sick fish belly portion of plane to find, liver turns white oedema, and abdominal cavity and mesenterium adhere to significant quantities of fat block, and the electromicroscopic photograph of liver finds, nuclear membrane dissolves, mitochondrial swelling and vacuolation, endomembrane system are disorderly.
Cause the reason of Pelteobagrus fulvidraco nutritional fatty liver to have a lot, comprise that mixed feed nutrition is unbalanced, fat content is higher, heavy metals exceeding standard, breeding environment worsen.Nutrition intake inequality easily causes fat to accumulate in liver and abdominal cavity, Pelteobagrus fulvidraco artifical compound feed commercially available at present too asks most low cost, reduce good protein content, make feed nitrogen energy uneven, lack crucial trophic factors, the anti-Adipocyte Factor of interpolation is not attached great importance to, makes cultivation Pelteobagrus fulvidraco frequently occur alimentary fat hepatopathy.Therefore, be necessary to provide a kind of yellow-head catfish feed additive with liver protecting effect, the economic loss that prevention and therapy Pelteobagrus fulvidraco fatty liver causes.At present, the relevant report of any yellow-head catfish feed additive and application thereof about having liver protecting effect is not also disclosed both at home and abroad.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of deposition that obviously can reduce fat in Pelteobagrus fulvidraco liver and abdominal cavity, improves the yellow-head catfish feed additive with liver protecting effect and the application thereof of the grazing rate of Pelteobagrus fulvidraco.
The present invention solves the problems of the technologies described above adopted technical scheme:
1. have the yellow-head catfish feed additive of liver protecting effect, this feed addictive is made up of following raw material: catch up with yellow grass, rhizoma alismatis, the root bark of tree peony, garlic, hawthorn and the fruit of Chinese wolfberry.
Be made up of following raw material and parts by weight thereof: catch up with yellow grass 15 ~ 25 parts, rhizoma alismatis 10 ~ 30 parts, the root bark of tree peony 10 ~ 30 parts, 5 ~ 15 parts, garlic, hawthorn 10 ~ 20 parts, the fruit of Chinese wolfberry 10 ~ 20 parts.
Preferably be made up of following raw material and parts by weight thereof: catch up with yellow grass 20 parts, rhizoma alismatis 20 parts, the root bark of tree peony 20 parts, 10 parts, garlic, hawthorn 15 parts, the fruit of Chinese wolfberry 15 parts.
2, have an application for the yellow-head catfish feed additive of liver protecting effect, the addition of this feed addictive in yellow-head catfish feed is 5 ~ 10%.
The addition of this feed addictive in yellow-head catfish feed is 5 ~ 6%.Addition Homogeneous phase mixing by 5 ~ 6% can prevent the generation of fatty liver in yellow-head catfish feed.
The addition of this feed addictive in yellow-head catfish feed is 8 ~ 10%.Addition Homogeneous phase mixing by 8 ~ 10% can play the effect for the treatment of fatty liver in yellow-head catfish feed.
Compared with prior art, the invention has the advantages that: a kind of yellow-head catfish feed additive with liver protecting effect of the present invention, form by catching up with yellow grass, rhizoma alismatis, the root bark of tree peony, garlic, hawthorn and the fruit of Chinese wolfberry, the active ingredient of wherein catching up with yellow grass is flavones, gallic acid, Quercetin, sitosterol, pinocembrin-7-O-glucoside, has obvious protecting liver, lowering enzymes and antioxidation; Rhizoma alismatis can be alleviated and takes in by high fat the fatty liver symptom caused, and contained triterpenoid, by affect fatty acid decomposition, reduces the synthesis of acetyl coenzyme A, thus reduction cholesterol levels; The root bark of tree peony has obvious inhibitory action to lipolysis, avoids free fatty to the infringement of liver, also has simultaneously and improves immunity, anti-inflammatory and bacteriostasis; Garlic can increase the excretion of allocholestanone alcohol and acid keto-alcohol, reduces the synthesis of lipid in raw in lipid and liver, reduces cholesterol and content of fatty acid, also have obvious bacteriostasis simultaneously; Hawthorn and the fruit of Chinese wolfberry have the deposition alleviating liver cell lipid and the effect reducing blood fat.Above-mentioned raw materials, by reasonable compatibility of the present invention, obviously can reduce the deposition of fat in Pelteobagrus fulvidraco liver and abdominal cavity, reverses Pelteobagrus fulvidraco fatty liver and liver edematous condition to a certain extent; The grazing rate of Pelteobagrus fulvidraco can be significantly improved, cultivation Pelteobagrus fulvidraco is played well protect the liver, the effect of prevention and therapy fatty liver.
Show through inventor's experimental result, above-mentioned feed addictive adds in the higher yellow-head catfish feed of fat content by the dosage by 5 ~ 10%, and experiment fish liver body is than reduction by 5 ~ 10%, and abdominal cavity fat coefficient reduces by 3 ~ 10%, liver oedema is obviously alleviated, and food ration improves 15 ~ 20%.The present invention operates less demanding, easily grasps and implements, can not damage cultured fishes and people.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
One, specific embodiment
Embodiment 1
A kind of yellow-head catfish feed additive with liver protecting effect; its active ingredient, for catching up with yellow grass, rhizoma alismatis, the root bark of tree peony, garlic, hawthorn, the fruit of Chinese wolfberry, is made up of following raw material and parts by weight thereof: catch up with yellow grass 15 ~ 25 parts, rhizoma alismatis 10 ~ 30 parts, the root bark of tree peony 10 ~ 30 parts, 5 ~ 15 parts, garlic, hawthorn 10 ~ 20 parts, the fruit of Chinese wolfberry 10 ~ 20 parts.
Embodiment 2
There is the yellow-head catfish feed additive of liver protecting effect, be made up of following raw material and parts by weight thereof: catch up with yellow grass 20 parts, rhizoma alismatis 20 parts, the root bark of tree peony 20 parts, 10 parts, garlic, hawthorn 15 parts, the fruit of Chinese wolfberry 15 parts.
Embodiment 3
There is the yellow-head catfish feed additive of liver protecting effect, be made up of following raw material and parts by weight thereof: catch up with yellow grass 15 parts, rhizoma alismatis 10 parts, the root bark of tree peony 20 parts, 15 parts, garlic, hawthorn 20 parts, the fruit of Chinese wolfberry 20 parts.
Embodiment 4
There is the yellow-head catfish feed additive of liver protecting effect, be made up of following raw material and parts by weight thereof: catch up with yellow grass 25 parts, rhizoma alismatis 25 parts, the root bark of tree peony 25 parts, 5 parts, garlic, hawthorn 10 parts, the fruit of Chinese wolfberry 10 parts.
Embodiment 5
There is the yellow-head catfish feed additive of liver protecting effect, be made up of following raw material and parts by weight thereof: catch up with yellow grass 18 parts, rhizoma alismatis 30 parts, the root bark of tree peony 30 parts, 8 parts, garlic, hawthorn 12 parts, the fruit of Chinese wolfberry 18 parts.
Two, Application Example
A kind of application with the yellow-head catfish feed additive of liver protecting effect of the present invention, its active ingredient forms by catching up with yellow grass, rhizoma alismatis, the root bark of tree peony, garlic, hawthorn, the fruit of Chinese wolfberry.To have the yellow-head catfish feed additive of liver protecting effect in embodiment 1 in above-mentioned specific embodiment, raw material crosses 60 order mesh screens after pulverizing, and adds in feed in proportion after mixing.This feed addictive addition in yellow-head catfish feed is 5 ~ 6% generations that can prevent fatty liver; Addition is 8 ~ 10% effects can playing treatment fatty liver, below lifts partial example and is described.
Embodiment 1
Take and catch up with yellow careless 200g, rhizoma alismatis 200g, root bark of tree peony 200g, garlic 100g, hawthorn 200g, fruit of Chinese wolfberry 200g, obtain 1kg additive, Pelteobagrus fulvidraco special feed (Ningbo Tianbang Co., Ltd is added respectively to by 0%, 3%, 6% dosage, Pelteobagrus fulvidraco No. 0 material) in be configured to test feed, the Pelteobagrus fulvidraco of nursing original body mass (2.0 ± 0.15) g 12 weeks, the results are shown in following table
As seen from the above table, 6% interpolation group Pelteobagrus fulvidraco liver body than and abdominal cavity fat coefficient be starkly lower than 0% and 3% interpolation group; And the opisthosoma of 6% interpolation group Pelteobagrus fulvidraco is heavy is obviously better than 0% and 3% interpolation group.Dissect and find, the liver body of 6% interpolation group Pelteobagrus fulvidraco is scarlet, without oedema.
Embodiment 2.
Take and catch up with yellow careless 250g, rhizoma alismatis 250g, root bark of tree peony 250g, garlic 50g, hawthorn 100g, fruit of Chinese wolfberry 100g, obtain 1kg additive, add in Pelteobagrus fulvidraco special feed (Ningbo Tianbang Co., Ltd, Pelteobagrus fulvidraco No. 1 material) by 10% dosage and be configured to test feed.Pelteobagrus fulvidraco (5.0 ± 0.55) g feeding high lipid food (fat content about 30%) of ingesting for a long time reaches 8 weeks, the results are shown in following table.
Survival rate (%) Liver body ratio (%) Abdominal cavity fat coefficient (%)
Experimental group 100.00 1.09 2.74
Control group 85.33 4.78 6.45
As seen from the above table, experimental group survival rate is 100.00%, and control group survival rate is 85.33%; Experimental group liver body is significantly less than control group 4.78% than 1.09%; Control group abdominal cavity fat coefficient 2.74% is significantly less than control group 6.45%.Liver Ultrastructural observation finds, experimental group liver organization is even, and control group observes that nuclear membrane dissolves, mitochondrial swelling and vacuolation, endomembrane system are disorderly.
Certainly, above-mentioned explanation is not limitation of the present invention, and the present invention is also not limited to above-mentioned citing.Those skilled in the art are in essential scope of the present invention, and the change made, remodeling, interpolation or replacement, also should belong to protection scope of the present invention.

Claims (6)

1. there is the yellow-head catfish feed additive of liver protecting effect, it is characterized in that this feed addictive is made up of following raw material: catch up with yellow grass, rhizoma alismatis, the root bark of tree peony, garlic, hawthorn and the fruit of Chinese wolfberry.
2. a kind of yellow-head catfish feed additive with liver protecting effect according to claim 1, is characterized in that being made up of following raw material and parts by weight thereof: catch up with yellow grass 15 ~ 25 parts, rhizoma alismatis 10 ~ 30 parts, the root bark of tree peony 10 ~ 30 parts, 5 ~ 15 parts, garlic, hawthorn 10 ~ 20 parts, the fruit of Chinese wolfberry 10 ~ 20 parts.
3. a kind of yellow-head catfish feed additive with liver protecting effect according to claim 2, is characterized in that being made up of following raw material and parts by weight thereof: catch up with yellow grass 20 parts, rhizoma alismatis 20 parts, the root bark of tree peony 20 parts, 10 parts, garlic, hawthorn 15 parts, the fruit of Chinese wolfberry 15 parts.
4. a kind of application with the yellow-head catfish feed additive of liver protecting effect according to Claims 2 or 3, is characterized in that: the addition of this feed addictive in yellow-head catfish feed is 5 ~ 10%.
5. a kind of application with the yellow-head catfish feed additive of liver protecting effect according to claim 4, is characterized in that: the addition of this feed addictive in yellow-head catfish feed is 5 ~ 6%.
6. a kind of application with the yellow-head catfish feed additive of liver protecting effect according to claim 4, is characterized in that: the addition of this feed addictive in yellow-head catfish feed is 8 ~ 10%.
CN201510251708.9A 2015-05-18 2015-05-18 Pelteobagrus fulvidraco feed additive with liver protection function and application thereof Pending CN104839486A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105285508A (en) * 2015-11-23 2016-02-03 王再青 Feed for improving disease resistance of pelteobagrus fulvidraco
CN105961923A (en) * 2016-06-17 2016-09-28 安庆市皖宜季牛水产养殖有限责任公司 Low-cost high-protein multienzyme juvenile pelteobagrus fulvidraco feed capable of promoting digestion
CN108606165A (en) * 2018-04-19 2018-10-02 广东联鲲集团有限公司 It is a kind of to improve the additive and its application that Pelteobagrus fulvidraco enteron aisle hardens

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102228137A (en) * 2011-06-10 2011-11-02 广东粤佳饲料有限公司 Chinese medicinal herb feed additive for controlling nutritional type hepatobiliary syndrome of cultured freshwater fishes
CN103877193A (en) * 2012-12-20 2014-06-25 赵翠 Medicine for treating hepatopathy
CN103989023A (en) * 2014-06-09 2014-08-20 中山大学 Special anti-fatty liver additive for hybrid snakehead and preparation method thereof

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
CN102228137A (en) * 2011-06-10 2011-11-02 广东粤佳饲料有限公司 Chinese medicinal herb feed additive for controlling nutritional type hepatobiliary syndrome of cultured freshwater fishes
CN103877193A (en) * 2012-12-20 2014-06-25 赵翠 Medicine for treating hepatopathy
CN103989023A (en) * 2014-06-09 2014-08-20 中山大学 Special anti-fatty liver additive for hybrid snakehead and preparation method thereof

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105285508A (en) * 2015-11-23 2016-02-03 王再青 Feed for improving disease resistance of pelteobagrus fulvidraco
CN105961923A (en) * 2016-06-17 2016-09-28 安庆市皖宜季牛水产养殖有限责任公司 Low-cost high-protein multienzyme juvenile pelteobagrus fulvidraco feed capable of promoting digestion
CN108606165A (en) * 2018-04-19 2018-10-02 广东联鲲集团有限公司 It is a kind of to improve the additive and its application that Pelteobagrus fulvidraco enteron aisle hardens
CN108606165B (en) * 2018-04-19 2022-02-11 广东联鲲集团有限公司 Additive for improving intestinal sclerosis of pelteobagrus fulvidraco and application thereof

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Inventor after: Li Ming

Inventor after: Chen Yixuan

Inventor after: Wang Ricuan

Inventor before: Li Ming

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Application publication date: 20150819

RJ01 Rejection of invention patent application after publication