CN105831481A - Special anti-stress enhancer for black sea bream and application thereof - Google Patents
Special anti-stress enhancer for black sea bream and application thereof Download PDFInfo
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- CN105831481A CN105831481A CN201610170489.6A CN201610170489A CN105831481A CN 105831481 A CN105831481 A CN 105831481A CN 201610170489 A CN201610170489 A CN 201610170489A CN 105831481 A CN105831481 A CN 105831481A
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- 239000003623 enhancer Substances 0.000 title abstract 4
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Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
- Y02A40/81—Aquaculture, e.g. of fish
- Y02A40/818—Alternative feeds for fish, e.g. in aquacultures
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses a special anti-stress enhancer for black sea bream and an application thereof. The invention is characterized in that the special anti-stress enhancer is composed of the following raw materials (by weight): 20-35 parts of angelica sulphated polysaccharide, 7-20 parts of vitamin C palmitate, 10-25 parts of total flavonoids of semen ziziphi spinosae, 15-25 parts of a rhizoma acori graminei extract, 5-15 parts of chromium baicalein and 3-10 parts of gamma-schizandrin. The immunoenhancer accounts for 1-2% of mass of a feed for black sea bream. The product of the invention has the following advantages: stress reaction can be relived, anti-stress capability is raised, and immunity is boosted. The anti-stress enhancer just accounts for 1-2% of mass of the feed, but average final weight of black sea bream can be raised by 20.1-48.8% and survival rate is enhanced by 11.67-25.83%.
Description
Technical field
The present invention relates to the feed additive of a kind of aquatic fish, especially relate to a kind of black porgy special anti-stress reinforcing agent and application thereof.
Background technology
Black porgy, belongs to Perciformes, Channa argus section, and Channa argus belongs to, because of its delicious meat, is of high nutritive value, very popular in countries and regions such as China's southeastern coast and Japan, Taiwan, Southeast Asia, is a famous and precious marine fish of class.Black porgy belongs to omnivorousness, and vitality is strong, and premunition is strong, relatively wide to the subject range of salinity and temperature, is one of the improved seeds of sea-farming.But during intensive artificial cultivation, face the stimulus effects of numerous stressors, such as water pollution, water temperature changes, scaring, food nutrition are bad, the invasion and attack of nuisance, and fish for, transport, feed miscarriage etc., various stress, the normal growth that not only can directly affect animal is grown, and the immunity of organisms of fish seriously may be caused to decline, induce ill and the most dead, thus had a strong impact on economic benefit and the ecological benefits of cultivation.Therefore, in feedstuff, anti-stress reinforcing agent is added significant.Anti-stress reinforcing agent, refer to have alleviation, preventing and treating by stressor cause stress the feed additive of syndrome.Can overcome or alleviated by the loss because causing, strengthen fish body to the resistance of undesirable element and immunity, improve survival rate.At present, relevant report and patented invention about black porgy special anti-stress reinforcing agent are less.
Summary of the invention
The technical problem to be solved is to provide one can alleviate stress, improve anti-stress ability, the black porgy special anti-stress reinforcing agent of enhancing immunity and application thereof, this anti-stress additive adds only 1%～2% in feedstuff, the average end that just can make black porgy heavily improves 20.1%～48.8%, and survival rate improves 11.67%～25.83%
The present invention solves the technical scheme that above-mentioned technical problem used: a kind of black porgy special anti-stress reinforcing agent, it is made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 20～35, sodium L-ascorbate-2-phosphate 7～20, Semen Ziziphi Spinosae total flavonoids 10～25, Rhizoma Acori Graminei extract 15～25, baicalin chromium 5～15γ -Schizandrin 3～10.
Preferably it is made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 32, sodium L-ascorbate-2-phosphate 13, Semen Ziziphi Spinosae total flavonoids 19, Rhizoma Acori Graminei extract 18, baicalin chromium 9,γ -Schizandrin 7.
The application of above-mentioned black porgy special anti-stress reinforcing agent, this immunostimulant interpolation mass percent in black porgy feedstuff is 1～2%.
Compared with prior art, it is an advantage of the current invention that: the invention discloses anti-stress additive and the application thereof of a kind of black porgy.In the formula of above-mentioned anti-stress additive, Radix Angelicae Sinensis polysaccharide, for the water soluble ingredient that Radix Angelicae Sinensis is main, the immunocytes such as T, bone-marrow-derived lymphocyte, macrophage, natural killer cell can be activated, the generation of cytokine, activating complement system can be promoted, promote antibody and the generation of immune protein, thus the immune system of black porgy is played regulation effect, recover and strengthen the immunity of black porgy, improve its antibacterial, ability of antiviral.And Radix Angelicae Sinensis sulfated polysaccharide, it is by Radix Angelicae Sinensis polysaccharide, is formed after Sulfation, after introducing sulfate group, its function is substantially strengthened.Sodium L-ascorbate-2-phosphate, formed by vitamin C esterification, it it is the relatively broad vitamin derivative of a kind of range of application, there is ascorbic various biological activity, it is possible to strengthen the immunity of black porgy, promote black porgy Complement C_3, the synthesis of C4, alleviate the black porgy complement content owing to causing to decline, improve it and maintain homeostatic ability, reduce black porgy to stress sensitivity, thus improve the ability of black porgy anti-stress；And vitamin C is after esterification, can change its dissolution characteristics, strengthen ascorbic stability.Semen Ziziphi Spinosae total flavonoids, for the extract of Chinese medicine Semen Ziziphi Spinosae, can suppress the excitement of maincenter, there is mind calming, the function such as calm the nerves, black porgy because stress movable strengthen, motion increases, overhead stream inverse enter, restlessness, add Semen Ziziphi Spinosae total flavonoids and can suppress the excitement of black porgy maincenter, play the effect of tranquilizing soporific.Rhizoma Acori Graminei extract, Rhizoma Acori Graminei has the function of regulation central nervous system, can play calm anticonvulsant effect, so that the black porgy under stress state is kept quite, alleviate and reduce the damage that stress cause.Baicalin chromium, it is baicalin and the organic chromium of chromium formation, there is effect of baicalin and chromium, can antiinflammatory, antibacterial, blood pressure lowering, calmness etc., and the function of black porgy insulin can be strengthened, increase the storage of its muscle glycogen, under emergency rating, the black porgy utilization to glucose can be strengthened, strengthen anti-stress ability, improve survival rate.γ -Schizandrin, Fructus Schisandrae Chinensis extrat, can make cerebral cortex excited and process of inhibition is strengthened, and promotes both balances, thus has stable and anticonvulsant physiologically active, thus strengthens the black porgy resistance to stress.The composition more than added, the most individually adds, and the effect that can play complementation is added in mixing, and effect becomes apparent from, compound anti-stress additive, has calmness, blood pressure lowering, minimizing heat production, improves appetite and the effect of digestion power, health invigorating and anti-stress ability.
In sum, one black porgy special anti-stress reinforcing agent of the present invention and application thereof, test result indicate that through inventor, under the coordinated effect of each composition, anti-stress additive of the present invention adds only 1%～2% in feedstuff, the weightening finish that just can make black porgy improves 20.1%～48.8%, and survival rate improves 11.67%～25.83%
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
One, specific embodiment
A kind of black porgy special anti-stress reinforcing agent, is made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 20～35, sodium L-ascorbate-2-phosphate 7～20, Semen Ziziphi Spinosae total flavonoids 10～25, Rhizoma Acori Graminei extract 15～25, baicalin chromium 5～15,γ -Schizandrin 3～10.Its preparation method: go above-mentioned raw materials to mix in proportion after pulverizing respectively, be dried.
Embodiment 1
A kind of black porgy special anti-stress reinforcing agent, is made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 20, sodium L-ascorbate-2-phosphate 7, Semen Ziziphi Spinosae total flavonoids 10, Rhizoma Acori Graminei extract 15, baicalin chromium 5,γ -Schizandrin 3.Its preparation method: take respectively after above-mentioned raw materials is pulverized and mix in proportion, be dried.
Embodiment 2
A kind of black porgy special anti-stress reinforcing agent, is made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 29, sodium L-ascorbate-2-phosphate 15, Semen Ziziphi Spinosae total flavonoids 15, Rhizoma Acori Graminei extract 17, baicalin chromium 12,γ -Schizandrin 9.Its preparation method: take respectively after above-mentioned raw materials is pulverized and mix in proportion, be dried.
Embodiment 3
A kind of black porgy special anti-stress reinforcing agent, is made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 35, sodium L-ascorbate-2-phosphate 20, Semen Ziziphi Spinosae total flavonoids 25, Rhizoma Acori Graminei extract 25, baicalin chromium 15,γ -Schizandrin 10.Its preparation method: take respectively after above-mentioned raw materials is pulverized and mix in proportion, be dried.
Embodiment 4
A kind of black porgy special anti-stress reinforcing agent, is made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 32, sodium L-ascorbate-2-phosphate 13, Semen Ziziphi Spinosae total flavonoids 19, Rhizoma Acori Graminei extract 18, baicalin chromium 9,γ -Schizandrin 7.Its preparation method: take respectively after above-mentioned raw materials is pulverized and mix in proportion, be dried.
Two, Application Example
Test example
Breed variety: Xiangshan Bay nursery completes culture experiment in Xiangshan County of Ningbo City, chooses the same a collection of black porgy seedling that nursery is hatched then, average weight about 3.77 grams, and body constitution is healthy and strong, juvenile fish 600 tail of anosis wound.It is divided into 5 test group, often organizes 120 tails, raise respectively in 5 identical seawater cages (1.5m × 1.5m × 1.5m), support temporarily with normal feedstuff 7 days, be allowed to adapt to environment.Normal feedstuff forms: imported fish meal 20.0%, bean cake 10.0%, casein 19.0%, flour 30.0%, import fish oil 6.22%, multidimensional 0.5%, many ore deposits 1.5%, choline chloride 0.2%, dalcium biphosphate 1.5%, cellulose 11.08%.
Aquaculture management: other cultivating conditions are suitable and identical, except that test group 1 is thrown something and fed adds the normal feedstuff of 1.5wt% embodiment 1 anti-stress reinforcing agent, test group 2 is thrown something and fed and is added the normal feedstuff of 1.5wt% embodiment 2 anti-stress reinforcing agent, test group 3 is thrown something and fed and is added the normal feedstuff of 1.5wt% embodiment 3 anti-stress reinforcing agent, test group 4 is thrown something and fed and is added the normal feedstuff of 1.5wt% embodiment 4 anti-stress reinforcing agent, test group 5 is thrown something and fed normal feedstuff, with comparing.Every day throws something and feeds 2 times sooner or later, the method for breeding that all using is satiated with food throws something and feeds.Above-mentioned immunostimulant addition in normal feedstuff is alternatively 1% or 2%.
Results contrast: after cultivating 8 weeks, result is analyzed.
Survival rate: survival rate=100* survival mantissa/initial mantissa.
Table 1 black porgy survival rate analysis (%)
| Test group number | Test group 1 | Test group 2 | Test group 3 | Test group 4 | Test group 5(matched group) |
| Average end weight | 25.1 | 26.3 | 30.2 | 31.1 | 20.9 |
| Survival mantissa | 101 | 107 | 111 | 118 | 87 |
| Survival rate % | 84.17 | 89.17 | 92.50 | 98.33 | 72.50 |
From table 1 it follows that average end weight and the survival rate of black porgy are substantially high than matched group (test group 5) in test group 1～4, average end heavily improves 20.1%～48.8%, and survival rate improves 11.67%～25.83%.Illustrate that black porgy of the present invention special anti-stress reinforcing agent can significantly improve the anti-stress ability of black porgy, promote growth, improve its survival rate etc..
Certainly, described above not limitation of the present invention, the present invention is also not limited to the example above.Those skilled in the art, in the essential scope of the present invention, the change made, retrofit, add or replace, and also should belong to protection scope of the present invention.
Claims (3)
1. a black porgy special anti-stress reinforcing agent, it is characterised in that be made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 20～35, sodium L-ascorbate-2-phosphate 7～20, Semen Ziziphi Spinosae total flavonoids 10～25, Rhizoma Acori Graminei extract 15～25, baicalin chromium 5～15,γ～schizandrin 3～10.
A kind of black porgy special anti-stress reinforcing agent the most according to claim 1, it is characterised in that be made up of following raw material and parts by weight thereof: Radix Angelicae Sinensis sulfated polysaccharide 32, sodium L-ascorbate-2-phosphate 13, Semen Ziziphi Spinosae total flavonoids 19, Rhizoma Acori Graminei extract 18, baicalin chromium 9,γ -Schizandrin 7.
3. the application of the black porgy special anti-stress reinforcing agent according to any one of a claim 1～2, it is characterised in that: this immunostimulant interpolation mass percent in black porgy feedstuff is 1～2%.
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| CN110012969A (en) * | 2019-05-23 | 2019-07-16 | 盐城恒兴饲料有限公司 | A kind of resisting stress additive of cray and its application |
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