CN104797935B - 用于癌症转移的预后和治疗的方法 - Google Patents
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- CN104797935B CN104797935B CN201380027292.1A CN201380027292A CN104797935B CN 104797935 B CN104797935 B CN 104797935B CN 201380027292 A CN201380027292 A CN 201380027292A CN 104797935 B CN104797935 B CN 104797935B
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
- G01N2333/4706—Regulators; Modulating activity stimulating, promoting or activating activity
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- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
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- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
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- Microbiology (AREA)
- Hospice & Palliative Care (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
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- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261621949P | 2012-04-09 | 2012-04-09 | |
| EP12382139.9A EP2650682A1 (en) | 2012-04-09 | 2012-04-09 | Method for the prognosis and treatment of cancer metastasis |
| EP123821399 | 2012-04-09 | ||
| US61/621,949 | 2012-04-09 | ||
| US201261724807P | 2012-11-09 | 2012-11-09 | |
| US61/724,807 | 2012-11-09 | ||
| US201261732175P | 2012-11-30 | 2012-11-30 | |
| US61/732,175 | 2012-11-30 | ||
| PCT/IB2013/001204 WO2013153458A2 (en) | 2012-04-09 | 2013-03-15 | Method for the prognosis and treatment of cancer metastasis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104797935A CN104797935A (zh) | 2015-07-22 |
| CN104797935B true CN104797935B (zh) | 2018-04-27 |
Family
ID=45929479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380027292.1A Active CN104797935B (zh) | 2012-04-09 | 2013-03-15 | 用于癌症转移的预后和治疗的方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9702878B2 (enExample) |
| EP (3) | EP2650682A1 (enExample) |
| JP (4) | JP6381519B2 (enExample) |
| KR (2) | KR102252332B1 (enExample) |
| CN (1) | CN104797935B (enExample) |
| AU (1) | AU2013246618B9 (enExample) |
| BR (1) | BR112014025269B1 (enExample) |
| CA (1) | CA2891609C (enExample) |
| DK (2) | DK2836837T3 (enExample) |
| ES (2) | ES2798107T3 (enExample) |
| FI (1) | FI3825692T3 (enExample) |
| MX (1) | MX374827B (enExample) |
| WO (1) | WO2013153458A2 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2562274T3 (es) | 2010-10-06 | 2016-03-03 | Fundació Institut De Recerca Biomèdica (Irb Barcelona) | Procedimiento para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de mama |
| EP2650682A1 (en) | 2012-04-09 | 2013-10-16 | Fundació Privada Institut de Recerca Biomèdica | Method for the prognosis and treatment of cancer metastasis |
| ES2705237T3 (es) | 2012-06-06 | 2019-03-22 | Fundacio Inst De Recerca Biomedica Irb Barcelona | Método para el diagnóstico y el pronóstico de metástasis del cáncer de pulmón |
| US10119171B2 (en) | 2012-10-12 | 2018-11-06 | Inbiomotion S.L. | Method for the diagnosis, prognosis and treatment of prostate cancer metastasis |
| DK2906718T3 (da) | 2012-10-12 | 2019-07-01 | Inbiomotion Sl | Fremgangsmåde til diagnose, prognose og behandling af prostatakræftmetastase under anvendelse af c-maf |
| AU2014229505B2 (en) * | 2013-03-15 | 2020-02-27 | Fundacio Institut De Recerca Biomedica (Irb Barcelona) | Method for the prognosis and treatment of cancer metastasis |
| US20160032399A1 (en) * | 2013-03-15 | 2016-02-04 | Inbiomotion S.L. | Method for the Prognosis and Treatment of Renal Cell Carcinoma Metastasis |
| BR112015023510A2 (pt) | 2013-03-15 | 2017-10-10 | Fundacio Inst De Recerca Biomedica Irb Barcelona | método para o diagnóstico, prognóstico e tratamento de câncer metastático |
| JP6550045B2 (ja) * | 2013-10-09 | 2019-07-24 | フンダシオ、インスティトゥト、デ、レセルカ、ビオメディカ(イエレベ、バルセロナ)Fundacio Institut De Recerca Biomedica (Irb Barcelona) | 乳がんに由来する骨の転移がんの予後診断および処置のための方法 |
| JP2017538412A (ja) * | 2014-12-11 | 2017-12-28 | インバイオモーション エセ.エレ. | ヒトc−mafに対する結合メンバー |
| WO2016145294A1 (en) * | 2015-03-12 | 2016-09-15 | The University Of Chicago | Methods for determining prognosis for breast cancer patients |
| ES2883249T3 (es) * | 2015-03-17 | 2021-12-07 | Mayo Found Medical Education & Res | Métodos y materiales para evaluar y tratar el cáncer |
| WO2017044715A1 (en) * | 2015-09-09 | 2017-03-16 | Somalogic, Inc. | Methods for developing personalized drug treatment plans and targeted drug development based on proteomic profiles |
| CA3021445A1 (en) * | 2016-04-19 | 2017-10-26 | Exelixis, Inc. | Triple negative breast cancer treatment method |
| CN117230193A (zh) * | 2016-05-25 | 2023-12-15 | 生物运动有限公司 | 基于c-maf状态的乳腺癌治疗性治疗 |
| CN105907886A (zh) * | 2016-07-07 | 2016-08-31 | 蔡维泺 | miR-124在乳腺癌骨转移疾病中的应用 |
| JP7108631B2 (ja) | 2017-01-06 | 2022-07-28 | パルヴェラ セラピューティクス、インク. | mTOR阻害剤の無水組成物およびその使用方法 |
| CN108796071A (zh) * | 2017-04-26 | 2018-11-13 | 中国科学院上海生命科学研究院 | 转移性乳腺癌标记物及其在诊断和治疗中的应用 |
| EP3713581A1 (en) * | 2017-11-22 | 2020-09-30 | Inbiomotion S.L. | Therapeutic treatment of breast cancer based on c-maf |
| KR102664243B1 (ko) * | 2018-01-19 | 2024-05-08 | 데루타-후라이 화마 가부시키가이샤 | 암 환자의 치료에 유용한 오줌의 알칼리제 |
| KR102224910B1 (ko) * | 2018-06-26 | 2021-03-05 | 재단법인 의약바이오컨버젼스연구단 | Rna 은 제자리 혼성화 방법을 통한 aimp2-dx2 신호 자동화 검출 방법 |
| CN110656171B (zh) * | 2018-06-28 | 2023-05-05 | 润安医学科技(苏州)有限公司 | 小核仁核糖核酸snord33作为生物标记物用于制备检测试剂盒中的用途 |
| JP2021530463A (ja) | 2018-07-02 | 2021-11-11 | パルヴェラ セラピューティクス、インク. | mTOR阻害剤の無水組成物および使用方法 |
| US12139764B2 (en) | 2018-11-14 | 2024-11-12 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Systems and methods for characterizing and treating breast cancer |
| WO2021062261A1 (en) * | 2019-09-25 | 2021-04-01 | The Trustees Of Columbia University In The City Of New York | Prognostic markers of metastatic cancer |
| CN112662763A (zh) * | 2020-03-10 | 2021-04-16 | 博尔诚(北京)科技有限公司 | 一种检测常见两性癌症的探针组合物 |
| CN112662764A (zh) * | 2020-03-17 | 2021-04-16 | 博尔诚(北京)科技有限公司 | 一种检测11种癌症的探针组合物 |
| JP7607330B2 (ja) * | 2021-04-30 | 2024-12-27 | 国立大学法人金沢大学 | 骨腫瘍の予後診断方法又は予後診断補助方法 |
| WO2022271702A1 (en) * | 2021-06-21 | 2022-12-29 | Palvella Therapeutics, Inc. | Methods and compositions for treating gorlin syndrome |
| IT202200001817A1 (it) | 2022-02-02 | 2023-08-02 | Aizoon S R L | Procedimento per la prognosi di una malattia in seguito ad un trattamento terapeutico, relativo sistema e prodotto informatico |
| WO2023158783A2 (en) * | 2022-02-18 | 2023-08-24 | Vuja De Sciences, Inc. | Methods, compositions, and combinations for preventing or treating cancer recurrence |
| IT202200005861A1 (it) | 2022-03-24 | 2023-09-24 | Aizoon S R L | Procedimento per stimare una variabile di interesse associata ad una data malattia in funzione di una pluralità di diversi dati omici, relativo dispositivo e prodotto informatico |
| CA3207405A1 (en) | 2022-07-25 | 2024-01-25 | Aizoon S.r.l. | Method for providing a clinical decision support, corresponding system for providing a clinical decision support, and computer program product |
| CN115919464B (zh) * | 2023-03-02 | 2023-06-23 | 四川爱麓智能科技有限公司 | 肿瘤定位方法、系统、装置及肿瘤发展预测方法 |
| CN119614707A (zh) * | 2025-01-13 | 2025-03-14 | 中山大学 | ERα生物标志物在ER+乳腺癌骨转移诊断、治疗和预后中的应用 |
| CN119662833B (zh) * | 2025-01-22 | 2025-08-15 | 中山大学孙逸仙纪念医院 | 基于肿瘤小泡中circCCDC50的Luminal型乳腺癌骨转移标记物、预测诊断试剂盒 |
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| CN103339265A (zh) * | 2010-10-06 | 2013-10-02 | 生物医学研究机构私人基金会 | 用于乳腺癌转移的诊断、预后和治疗的方法 |
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