CN104762666A - 双重运行盒 - Google Patents

双重运行盒 Download PDF

Info

Publication number
CN104762666A
CN104762666A CN201410858370.9A CN201410858370A CN104762666A CN 104762666 A CN104762666 A CN 104762666A CN 201410858370 A CN201410858370 A CN 201410858370A CN 104762666 A CN104762666 A CN 104762666A
Authority
CN
China
Prior art keywords
spe post
spe
post
methods according
reaction vessel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410858370.9A
Other languages
English (en)
Chinese (zh)
Inventor
X·弗兰齐
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Priority to CN202110731994.4A priority Critical patent/CN113564722A/zh
Publication of CN104762666A publication Critical patent/CN104762666A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/005—Sugars; Derivatives thereof; Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00495—Means for heating or cooling the reaction vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00709—Type of synthesis
    • B01J2219/00716—Heat activated synthesis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00731—Saccharides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
CN201410858370.9A 2013-11-13 2014-11-12 双重运行盒 Pending CN104762666A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110731994.4A CN113564722A (zh) 2013-11-13 2014-11-12 双重运行盒

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361903486P 2013-11-13 2013-11-13
US61/903486 2013-11-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202110731994.4A Division CN113564722A (zh) 2013-11-13 2014-11-12 双重运行盒

Publications (1)

Publication Number Publication Date
CN104762666A true CN104762666A (zh) 2015-07-08

Family

ID=51897262

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201410858370.9A Pending CN104762666A (zh) 2013-11-13 2014-11-12 双重运行盒
CN202110731994.4A Pending CN113564722A (zh) 2013-11-13 2014-11-12 双重运行盒

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202110731994.4A Pending CN113564722A (zh) 2013-11-13 2014-11-12 双重运行盒

Country Status (18)

Country Link
US (1) US10584078B2 (https=)
EP (1) EP3068747B1 (https=)
JP (1) JP6496726B2 (https=)
KR (1) KR102335535B1 (https=)
CN (2) CN104762666A (https=)
BE (1) BE1022357A9 (https=)
CA (1) CA2930479C (https=)
DE (2) DE202014010612U1 (https=)
DK (1) DK3068747T3 (https=)
ES (1) ES3005832T3 (https=)
FI (1) FI3068747T3 (https=)
HR (1) HRP20250050T1 (https=)
HU (1) HUE069777T2 (https=)
IL (1) IL235650B (https=)
PL (1) PL3068747T3 (https=)
PT (1) PT3068747T (https=)
RS (1) RS66442B1 (https=)
WO (1) WO2015071288A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126648A (zh) * 2018-01-04 2018-06-08 江苏华益科技有限公司 一种放射性药物的自动传输装置及方法
CN113413840A (zh) * 2021-06-04 2021-09-21 四川玖谊源粒子科技有限公司 一种用于制备多核素放射性药物的合成系统
CN113564722A (zh) * 2013-11-13 2021-10-29 通用电气健康护理有限公司 双重运行盒

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201420094D0 (en) 2014-11-12 2014-12-24 Ge Healthcare Ltd Flouride trapping arrangement
US10109385B2 (en) 2009-09-23 2018-10-23 Abt Molecular Imaging, Inc. Dose synthesis card for use with automated biomarker production system
GB201420093D0 (en) 2014-11-12 2014-12-24 Ge Healthcare Ltd Pet tracer purification system
CN107530455A (zh) * 2015-02-10 2018-01-02 Abt分子成像公司 与自动化生物标记物生产系统联用的剂量合成卡
GB201504287D0 (en) 2015-03-13 2015-04-29 Ge Healthcare Ltd Piercing device
NL2014828B1 (en) 2015-05-20 2017-01-31 Out And Out Chemistry S P R L Method of performing a plurality of synthesis processes of preparing a radiopharmaceutical in series, a device and cassette for performing this method.
EP3643707B1 (en) 2017-06-19 2022-02-23 Futurechem Co., Ltd. 18f-labelled compound for prostate cancer diagnosis, and use thereof
WO2018236115A1 (ko) 2017-06-19 2018-12-27 (주)퓨쳐켐 전립선암 진단을 위한 18f-표지된 화합물 및 그의 용도
CN115531963A (zh) * 2017-09-19 2022-12-30 株式会社村田制作所 过滤装置以及过滤方法
CN111107920A (zh) 2017-09-25 2020-05-05 株式会社村田制作所 过滤装置
BE1032491B1 (fr) 2024-03-27 2025-10-27 Trasis S A Synthèse de traceurs à plusieurs passages sur cassette

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1765911A (zh) * 2005-11-18 2006-05-03 南方医科大学南方医院 2－18f－2－脱氧－d－葡萄糖的合成工艺
CN101346391A (zh) * 2005-12-02 2009-01-14 日本医事物理股份有限公司 放射性氟标记化合物的制备方法
CN102292461A (zh) * 2008-12-22 2011-12-21 拜耳先灵医药股份有限公司 使用交换树脂合成放射性核素标记的化合物的方法
US20120108858A1 (en) * 2010-10-28 2012-05-03 Maxim Kiselev Method and device for manufacturing of radiopharmaceuticals

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5082980A (en) * 1990-06-13 1992-01-21 Case Western Reserve University Process and apparatus for synthesizing oxygen-15 labelled butanol for positron emission tomography
US7413714B1 (en) * 2000-07-16 2008-08-19 Ymc Co. Ltd. Sequential reaction system
JP4926546B2 (ja) 2006-05-30 2012-05-09 住友重機械工業株式会社 放射性薬液合成装置の使用方法、及び放射性薬液合成装置
CN101830937B (zh) * 2009-03-12 2012-06-06 张锦明 可视化、双反应管氟-18多功能自动化合成模块
CA2767475A1 (en) * 2009-07-10 2011-01-13 Bayer Pharma Aktiengesellschaft Usage of low to medium-pressure liquid chromatography for the purification of radiotracers
US10639608B2 (en) * 2010-04-08 2020-05-05 Siemens Medical Solutions Usa, Inc. System, device and method for preparing tracers and transferring materials during radiosynthesis
DE102010036356A1 (de) * 2010-07-12 2012-01-12 Abx Advanced Biochemical Compounds Gmbh Vorrichtung zur Synthese radioaktiv markierter Verbindungen
CA2823063C (en) * 2010-12-29 2020-08-11 Ge Healthcare Limited A method for preparation of f for use in a radiofluorination reaction
US20130060017A1 (en) 2011-07-15 2013-03-07 Cardinal Health 414, Llc Methods for synthesizing labeled compounds
GB201117786D0 (en) * 2011-10-14 2011-11-30 Ge Healthcare Ltd Eluent vial
GB201117785D0 (en) * 2011-10-14 2011-11-30 Ge Healthcare Ltd Improved radiosynthesis method
GB201120586D0 (en) * 2011-11-30 2012-01-11 Ge Healthcare Ltd Solid phase extraction neutralisation
ES3005832T3 (en) * 2013-11-13 2025-03-17 Ge Healthcare Ltd Dual run cassette for the synthesis of 18f-labelled compounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1765911A (zh) * 2005-11-18 2006-05-03 南方医科大学南方医院 2－18f－2－脱氧－d－葡萄糖的合成工艺
CN101346391A (zh) * 2005-12-02 2009-01-14 日本医事物理股份有限公司 放射性氟标记化合物的制备方法
CN102292461A (zh) * 2008-12-22 2011-12-21 拜耳先灵医药股份有限公司 使用交换树脂合成放射性核素标记的化合物的方法
US20120108858A1 (en) * 2010-10-28 2012-05-03 Maxim Kiselev Method and device for manufacturing of radiopharmaceuticals

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113564722A (zh) * 2013-11-13 2021-10-29 通用电气健康护理有限公司 双重运行盒
CN108126648A (zh) * 2018-01-04 2018-06-08 江苏华益科技有限公司 一种放射性药物的自动传输装置及方法
CN113413840A (zh) * 2021-06-04 2021-09-21 四川玖谊源粒子科技有限公司 一种用于制备多核素放射性药物的合成系统

Also Published As

Publication number Publication date
CN113564722A (zh) 2021-10-29
IL235650B (en) 2019-10-31
ES3005832T3 (en) 2025-03-17
RS66442B1 (sr) 2025-02-28
EP3068747A1 (en) 2016-09-21
HUE069777T2 (hu) 2025-04-28
BE1022357A9 (fr) 2017-02-02
FI3068747T3 (fi) 2024-12-30
EP3068747B1 (en) 2024-10-30
BE1022357B1 (fr) 2016-03-24
CA2930479A1 (en) 2015-05-21
WO2015071288A1 (en) 2015-05-21
PT3068747T (pt) 2025-01-24
PL3068747T3 (pl) 2025-03-10
US20160257622A1 (en) 2016-09-08
DK3068747T3 (da) 2025-01-13
IL235650A0 (en) 2015-02-26
DE202014010612U1 (de) 2016-04-19
KR102335535B1 (ko) 2021-12-08
JP2017503752A (ja) 2017-02-02
JP6496726B2 (ja) 2019-04-03
DE202015007501U1 (de) 2015-12-17
CA2930479C (en) 2023-03-28
US10584078B2 (en) 2020-03-10
HRP20250050T1 (hr) 2025-04-11
KR20160085769A (ko) 2016-07-18

Similar Documents

Publication Publication Date Title
CN104762666A (zh) 双重运行盒
DK2799091T3 (en) System, device and method for the preparation of tracers and transfer of materials during radiosynthesis
KR102159425B1 (ko) 플루오라이드 포획 배열체
KR20140097225A (ko) 가수분해 탈보호 단계 및 고체상 추출을 포함하는 18f-표지화 화합물의 제조
US10023525B2 (en) Preparation of 18F-fluciclovine
KR102155932B1 (ko) Pet 추적자 정제 시스템
KR20180016418A (ko) 방사성의약품의 제조를 위한 복수의 합성 공정들의 연속 수행 방법, 및 상기 방법을 수행하기 위한 장치 및 카세트
JP7478664B2 (ja) 安定化させた放射性標識反応

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
EXSB Decision made by sipo to initiate substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20150708