CN104758221A - Spider freeze-dried powder mosquito repellent liquid and preparation method thereof - Google Patents
Spider freeze-dried powder mosquito repellent liquid and preparation method thereof Download PDFInfo
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- CN104758221A CN104758221A CN201510008917.0A CN201510008917A CN104758221A CN 104758221 A CN104758221 A CN 104758221A CN 201510008917 A CN201510008917 A CN 201510008917A CN 104758221 A CN104758221 A CN 104758221A
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Abstract
The invention relates to the field of mosquito repellent liquids and discloses a spider freeze-dried powder mosquito repellent liquid and a preparation method thereof. The spider freeze-dried powder mosquito repellent liquid utilizes spider freeze-dried powder as a main agent and through compatibility, the spider freeze-dried powder mosquito repellent liquid has substantial mosquito repellent effects. Aiming at symptoms of redness, swelling and itching caused by mosquito bites, the spider freeze-dried powder mosquito repellent liquid has good effects of preventing scar, relieving itching, eliminating swelling and relieving pain. In subtropical zones and tropical rain forest zones, the spider freeze-dried powder mosquito repellent liquid has substantial effects of repelling mosquitoes, eliminating swelling, relieving itching, resisting bacteria and diminishing inflammation.
Description
Technical field
The present invention relates to mosquito water field, refer to a kind of spider freeze-drying powder mosquito water and preparation method thereof especially.
Background technology
Mosquito stabs skin by its mouthpart, and its saliva or venom invade skin, and owing to containing plurality of antigens composition in the saliva of mosquito or the leachate of poison gland, these antigens can produce atopic reaction with antibody and cause inflammation after entering human body skin.Time serious, few patients local produces the severe reaction such as bulla, hemorrhagic necrosis, is dermatology common disease disease in summer.Hainan Tropical rainforest area mosquito quantity is many, wide variety, and higher to the requirement of mosquito dispersing medicine, general mosquito dispersing water is difficult to meet its requirement.In addition, existing mosquito dispersing preparation, mostly containing chemical composition, and mosquito-repelling effect is limited.Therefore, exploitation has mosquito-repelling effect mosquito dispersing glassware for drinking water that is good, that have Comprehensive Treatment effect and is of great importance.
Aranea is the natural enemy of mosquito, and its species enrich.There is kind more than 40000 in the whole world, in state-owned kind more than 4000." gold deficient " of the Eastern Han Dynasty carries: " Aranea removing blood stasis with potent drugs and subsiding a swelling." " wide profit side " year of the Tang Dynasty: " and control scorpion and bite people, Aranea grinds juice, deposited it." five generations " Japan hanako materia medica " carry: " Aranea, the main Serpentis of ancient prescription, honeybee, scorpion venom ... " " national Chinese herbal medicine compilation " year: " Aranea, antiinflammatory, removing toxic substances, address wasp and scorpion sting." along with deepening continuously of studying Aranea; the range of application of Aranea and extract thereof constantly expands; as Chinese invention patent CN1839887A discloses a kind of preparation method of spider freeze-drying powder and the application in medicine and health product; by preparing spider freeze-drying powder; active spider component damages is little, and process is simple.Chinese invention patent CN1840638 discloses a kind of spider health care wine and preparation method thereof, by Aranea and the compatibility such as Hippocampus, Cornu Cervi Pantotrichum, has significant antifatigue effect.
Summary of the invention
The present invention proposes a kind of spider freeze-drying powder mosquito water and preparation method thereof, select spider freeze-drying powder to be principal agent, by compatibility, there is mosquito dispersing, anti-to bite, effect of antipruritic, reducing swelling and alleviating pain.
Technical scheme of the present invention is achieved in that
A kind of spider freeze-drying powder mosquito water, comprises the component of following mass fraction: spider freeze-drying powder 20-60 part, Flos Lonicerae 1-30 part, Flos Chrysanthemi Indici 1-30 part, Fructus Cnidii 1-10 part, Borneolum Syntheticum 1-5 part, quintessence oil 1-5 part, Herba Taraxaci 0-20 part.
Further, spider freeze-drying powder 30-50 part, Flos Lonicerae 10-20 part, Flos Chrysanthemi Indici 10-20 part, Fructus Cnidii 2-8 part, Borneolum Syntheticum 2-4 part, quintessence oil 2-4 part, Herba Taraxaci 0-15 part.
Further, described spider freeze-drying powder derives from Selenocosmiahuwena.
Further, described spider freeze-drying powder derives from Jingzhao chilobrachys spider.
A preparation method for spider freeze-drying powder mosquito water, comprises the following steps:
(1) take Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii, Herba Taraxaci by formula ratio, add above-mentioned medical material total amount 5-8 ethanol doubly; Reflux, extract, 3 times, each 10-20 minute, merges 3 extracting solution, crosses and filters residue, decompression recycling ethanol, lyophilization, obtain medical material ethanol extraction;
(2) spider freeze-drying powder, Borneolum Syntheticum and quintessence oil is taken by formula ratio, mix with the medical material ethanol extraction of step (1) gained, add spider freeze-drying powder quality 10-30 dissolve with ethanol doubly, cross and filter insoluble matter, sterilizing, obtains spider freeze-drying powder mosquito water of the present invention.
Further, described step (1) reclaims control temperature 40-50 DEG C in ethanol process.
Further, the ethanol contend concentration added in described step (1) and step (2) is 75%-85%.
Beneficial effect of the present invention:
Spider freeze-drying powder mosquito water of the present invention, select spider freeze-drying powder as principal agent, be equipped with heat clearing away, removing toxic substances, dampness removing, the Flos Lonicerae of itching-relieving action, Flos Chrysanthemi Indici and Fructus Cnidii, and add Borneolum Syntheticum and quintessence oil, abnormal smells from the patient is unique, volatility is good, has significant mosquito-repelling effect; Also can add the Herba Taraxaci with mass dissipating and swelling eliminating effect in prescription, rising of producing due to mosquito bite wrap, the symptom such as to itch has good effect of stopping trace, antipruritic, reducing swelling and alleviating pain.Especially for the multiple mosquito in subtropical zone, Tropical rain forest area, there is significant mosquito dispersing, repellent antipruritic, antibacterial and anti-inflammation functions.
Aranea is to prey on mosquito for food, and the natural enemy of multiple mosquito, has significant mosquito dispersing effect.Simultaneously Aranea has antibacterial, Detoxication, the redness produced mosquito bite, plays bag, with and the various infection that cause there is detumescence, antipruritic, antibacterial, antiinflammatory, Detoxication.Be used as medicine with Aranea, Traditional Chinese Medicine method be Aranea boiled water is scalded extremely then dry, the method such as to dry makes Aranea and does, then pulverize, also have and go extract to be used as medicine by after Aranea extraction.But above processing method needs high-temperature heating, active spider component damages is comparatively large, affects giving full play to of Aranea drug effect.Adopt spider freeze-drying powder in the present invention, processing procedure does not need heating, and at utmost can preserve the bioactive ingredients in Aranea, after using, drug effect is remarkable.
Flos Lonicerae property is sweet cold, gas fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, and fragrance thoroughly reaches and can be eliminating evil.The aromatic odor of Flos Lonicerae, has good mosquito dispersing effect.Simultaneously Flos Lonicerae again can dispelling wind-heat, and also kind removing summer-heat blood poison, has good reducing swelling and alleviating pain effect for congestion and swelling pain.
Flos Chrysanthemi Indici is slightly cold, pungent, bitter, returns lung, Liver Channel, has heat-clearing and toxic substances removing, and effect of detumescence all has good curative effect to furuncle, carbuncle, erysipelas, eczema, dermatitis.
Fructus Cnidii is warm in nature, acrid in the mouth, hardship, has removing toxic substances, dampness, parasite killing, the effect of dispeling the wind.
Above medical material and the same use of spider freeze-drying powder, can form unique abnormal smells from the patient, mosquito dispersing effect is remarkable.And Flos Lonicerae in prescription, Flos Chrysanthemi Indici and Fructus Cnidii all have removing toxic substances, detumescence, the effect such as antipruritic, use same with spider freeze-drying powder, the redness that mosquito bite is caused, itch, the symptom such as rubescent, there is effect of good removing toxic substances, antipruritic, detumescence.
The redness caused for the mosquito bite that toxicity is larger, to itch, can add the Herba Taraxaci with eliminating stagnation, detumescence effect, accelerate blood circulation, promote the disappearance of lump in prescription, its removing toxic substances, detumescence, antipruritic effect are more remarkable.Especially for Tropical rain forest area, due to the weather conditions of uniqueness, mosquito quantity is many, wide variety, and general mosquito dispersing water is subsided a swelling, antipruritic effect is very poor.And still there is in prescription of the present invention good detumescence, antipruritic effect, after adding Herba Taraxaci, its removing toxic substances, detumescence, itching-relieving efficacies is more remarkable.
Borneolum Syntheticum main component is dextro Borneolum Syntheticum, abnormal smells from the patient delicate fragrance, has certain mosquito-repelling effect.Quintessence oil also has good volatility, the two again compatibility there is the spider freeze-drying powder of mosquito dispersing effect, and heat clearing away, removing toxic substances, dampness removing, the Flos Lonicerae of itching-relieving action, Flos Chrysanthemi Indici and Fructus Cnidii, form unique abnormal smells from the patient, while mosquito dispersing, also there is good removing toxic substances and promoting subsidence of swelling, antipruritic effect.Meanwhile, because Borneolum Syntheticum and quintessence oil have good volatility, the effective ingredient be conducive in prescription is vaporized in air, and the mosquito-repelling effect of prescription Chinese crude drug is more remarkable.And Borneolum Syntheticum and quintessence oil are easy to percutaneous absorbtion, to the absorption of other medical material in prescription, there is good facilitation, the removing toxic substances and promoting subsidence of swelling in prescription can be made, antipruritic effect better plays, reach the object of Quick itch stopping, detumescence.
In prescription, spider freeze-drying powder, as principal agent, effectively can prevent mosquito bite, significantly can alleviate redness that mosquito bite causes, infects, itch, have good Detoxication.Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii itself all have certain abnormal smells from the patient, have certain mosquito dispersing effect, use same with Aranea, and have the collaborative effect be added, its mosquito dispersing effect can strengthen mutually, better effects if.The kind poison that purifies the blood of Flos Lonicerae, Flos Chrysanthemi Indici clearing heat for detumescence, Fructus Cnidii removing toxic substances, dampness, above medical material and Aranea are with using, its removing toxic substances, detumescence, the Detoxication of heat clearing away effect to spider freeze-drying powder have great facilitation, and the toxin that mosquito bite can be promoted to produce is discharged fast or decomposes.Borneolum Syntheticum and volatile oil both can promote the volatilization of effective ingredient in prescription, can promote that again skin is to the absorption of medicine, and mosquito dispersing, removing toxic substances, detumescence effect are more remarkable.Quintessence oil can select Herba Lysimachiae foenum-graeci quintessence oil, Flos Lonicerae quintessence oil etc. according to the hobby of individual, makes mosquito dispersing glassware for drinking water have different odor, adapts to the demand of different crowd.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
A kind of spider freeze-drying powder mosquito water, is characterized in that, comprise the component of following mass fraction: spider freeze-drying powder 20g, Flos Lonicerae 1g, Flos Chrysanthemi Indici 1g, Fructus Cnidii 1g, Borneolum Syntheticum 1g, Flos Lonicerae quintessence oil 1g.
A preparation method for spider freeze-drying powder mosquito water, comprises the following steps:
(1) take Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii by formula ratio, add the ethanol of above-mentioned total amount medical material 5 times; Reflux, extract, 3 times, each 10 minutes, merges 3 extracting solution, crosses and filters residue, decompression recycling ethanol at 40 DEG C, lyophilization, obtain medical material ethanol extraction; Ethanol contend concentration used is 75%;
(2) spider freeze-drying powder, Borneolum Syntheticum and Flos Lonicerae quintessence oil is taken by formula ratio, mix with the medical material ethanol extraction of step (1) gained, add the dissolve with ethanol of spider freeze-drying powder quality 10 times, ethanol contend concentration used is 75%, cross and filter insoluble matter, sterilizing, obtains spider freeze-drying powder mosquito water of the present invention.
Embodiment 2
A kind of spider freeze-drying powder mosquito water, is characterized in that, comprise the component of following mass fraction: spider freeze-drying powder 60g, Flos Lonicerae 30g, Flos Chrysanthemi Indici 30g, Fructus Cnidii 10g, Borneolum Syntheticum 5g, Herba Lysimachiae foenum-graeci quintessence oil 5g, Herba Taraxaci 20g.
A preparation method for spider freeze-drying powder mosquito water, comprises the following steps:
(1) take Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii, Herba Taraxaci by formula ratio, add the ethanol of above-mentioned total amount medical material 8 times; Reflux, extract, 3 times, each 20 minutes, merges 3 extracting solution, and cross and filter residue, 50 DEG C of decompression recycling ethanols, lyophilization, obtains medical material ethanol extraction; Ethanol contend concentration used is 85%; (2) spider freeze-drying powder, Borneolum Syntheticum and Herba Lysimachiae foenum-graeci quintessence oil is taken by formula ratio, mix with the medical material ethanol extraction of step (1) gained, add the dissolve with ethanol of spider freeze-drying powder quality 30 times, ethanol contend concentration used is 85%, cross and filter insoluble matter, sterilizing, obtains spider freeze-drying powder mosquito water of the present invention.
Embodiment 3
A kind of spider freeze-drying powder mosquito water, comprises the component of following mass fraction: Selenocosmiahuwena lyophilized powder 30g, Flos Lonicerae 10g, Flos Chrysanthemi Indici 10g, Fructus Cnidii 2g, Borneolum Syntheticum 2g, Flos Rosae Rugosae quintessence oil 2g.
A preparation method for spider freeze-drying powder mosquito water, comprises the following steps:
(1) take Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii by formula ratio, add the ethanol of above-mentioned total amount medical material 5 times, ethanol contend concentration is 75%; Reflux, extract, 3 times, each 10 minutes, merges 3 extracting solution, and cross and filter residue, decompression recycling ethanol at temperature 40 DEG C, lyophilization, obtains medical material ethanol extraction;
(2) Selenocosmiahuwena lyophilized powder, Borneolum Syntheticum and Flos Rosae Rugosae quintessence oil is taken by formula ratio, mix with the medical material ethanol extraction of step (1) gained, add the dissolve with ethanol of spider freeze-drying powder quality 10 times, ethanol contend concentration is 75%, cross and filter insoluble matter, sterilizing, obtains spider freeze-drying powder mosquito water of the present invention.
Embodiment 4
A kind of spider freeze-drying powder mosquito water, comprises the component of following mass fraction: Jingzhao chilobrachy spider lyophilized powder 50g, Flos Lonicerae 20g, Flos Chrysanthemi Indici 20g, Fructus Cnidii 8g, Borneolum Syntheticum 4g, Peppermint essential oil 4g, Herba Taraxaci 15g.
A preparation method for spider freeze-drying powder mosquito water, comprises the following steps:
(1) take Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii, Herba Taraxaci by formula ratio, add the ethanol of above-mentioned total amount medical material 8 times, ethanol contend concentration is 80%; Reflux, extract, 3 times, each 20 minutes, merges 3 extracting solution, and cross and filter residue, decompression recycling ethanol at 50 DEG C of temperature, lyophilization, obtains medical material ethanol extraction;
(2) Jingzhao chilobrachy spider lyophilized powder, Borneolum Syntheticum and Peppermint essential oil is taken by formula ratio, mix with the medical material ethanol extraction of step (1) gained, add the dissolve with ethanol of spider freeze-drying powder quality 30 times, concentration of alcohol is 80%, cross and filter insoluble matter, sterilizing, obtains spider freeze-drying powder mosquito water of the present invention.
Embodiment 5
A kind of spider freeze-drying powder mosquito water, comprises the component of following mass fraction: Selenocosmiahuwena lyophilized powder 40 parts, Flos Lonicerae 15g, Flos Chrysanthemi Indici 15g, Fructus Cnidii 6g, Borneolum Syntheticum 3g, jasmin quintessence oil 3g, Herba Taraxaci 10g.
A preparation method for spider freeze-drying powder mosquito water, comprises the following steps:
(1) take Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii, Herba Taraxaci by formula ratio, add the ethanol of above-mentioned total amount medical material 7 times, ethanol contend concentration is 80%; Reflux, extract, 3 times, each 15 minutes, merges 3 extracting solution, crosses and filters residue, decompression recycling ethanol under temperature 45 C, lyophilization, obtain medical material ethanol extraction;
(2) Selenocosmiahuwena lyophilized powder, Borneolum Syntheticum and jasmin quintessence oil is taken by formula ratio, mix with the medical material ethanol extraction of step (1) gained, add the dissolve with ethanol of spider freeze-drying powder quality 20 times, ethanol contend concentration is 80%, cross and filter insoluble matter, sterilizing, obtains spider freeze-drying powder mosquito water of the present invention.
In above embodiment, according to personal like, quintessence oil can also select peony essential oil, Basil Essential, violet essential etc., makes mosquito-repellent water have different abnormal smells from the patients, adapts to the demand that people are various.
Spider freeze-drying powder mosquito water effect of the present invention
Respectively different place Stochastic choice 30 people, random point 4 groups, work, often organizes 5 people.Wherein 5 groups use the mosquito water of the present invention's 5 embodiment gained as experimental group respectively; 6th group uses Liushen toilet water as a control group.Select the more place such as waterside, the woods, thick grass, open deck of mosquito to try out, the time that record mosquito water plays a role, average, its result is as shown in table 1.
Table 1 spider freeze-drying powder mosquito of the present invention water trial effect
As shown in Table 1, by probation in different places, its mosquito repellent time can reach 5.5-7 hour, suitable with conventional Liushen toilet water repelling effect, evident in efficacy.After the spider freeze-drying powder mosquito water of use gained of the present invention is applied to the skin surface of mosquito bite simultaneously, abnormal smells from the patient delicate fragrance, unique cooling sensation can be produced, the symptom such as can eliminate redness fast, itch, there is good detumescence, antipruritic, anti-inflammation, Detoxication.
Tropical rain forest is warm, rainy all the year round, and plant growing is dense, and mosquito specie and quantity are all far above other areas.In process on probation, Liushen toilet water in contrast, in Tropical rain forest area, mosquito repellent time only has 2 hours, and to redness, the symptom treatment limited efficiency such as to itch that mosquito bite produces.And the mosquito water of the present invention's 3 embodiment gained, the mosquito dispersing time, the symptom simultaneously produced for mosquito bite had significant detumescence, itching-relieving action all more than 5 hours.The serious redness caused for the mosquito bite that some toxicity is larger, itch and wait symptom, Liushen toilet water cannot work substantially, and spider freeze-drying powder mosquito water of the present invention still has significant detumescence, antipruritic effect, and Detoxication is remarkable.
Embodiment 2,4 and 5 is owing to the addition of Herba Taraxaci in prescription, and its removing toxic substances, detumescence, antipruritic effect is especially remarkable.For the lump produced due to mosquito bite, rubescent, infection, the prescription adding Herba Taraxaci can be selected repeatedly to spray, reach better removing toxic substances, detumescence, antipruritic effect.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (7)
1. a spider freeze-drying powder mosquito water, is characterized in that, comprises the component of following mass fraction: spider freeze-drying powder 20-60 part, Flos Lonicerae 1-30 part, Flos Chrysanthemi Indici 1-30 part, Fructus Cnidii 1-10 part, Borneolum Syntheticum 1-5 part, quintessence oil 1-5 part, Herba Taraxaci 0-20 part.
2. a kind of spider freeze-drying powder mosquito water according to claim 1, is characterized in that, comprises component spider freeze-drying powder 30-50 part of following mass fraction, Flos Lonicerae 10-20 part, Flos Chrysanthemi Indici 10-20 part, Fructus Cnidii 2-8 part, Borneolum Syntheticum 2-4 part, quintessence oil 2-4 part, Herba Taraxaci 0-15 part.
3. a kind of spider freeze-drying powder mosquito water according to claim 1 and 2, is characterized in that: described spider freeze-drying powder derives from Selenocosmiahuwena.
4. a kind of spider freeze-drying powder mosquito water according to claim 1 and 2, is characterized in that: described spider freeze-drying powder derives from Jingzhao chilobrachys spider.
5. the preparation method of a kind of spider freeze-drying powder mosquito water according to any one of claim 1 to 5, comprises the following steps:
(1) take Flos Lonicerae, Flos Chrysanthemi Indici, Fructus Cnidii, Herba Taraxaci by formula ratio, add above-mentioned medical material total amount 5-8 ethanol doubly; Reflux, extract, 3 times, each 10-20 minute, merges 3 extracting solution, crosses and filters residue, decompression recycling ethanol, lyophilization, obtain medical material ethanol extraction;
(2) spider freeze-drying powder, Borneolum Syntheticum and quintessence oil is taken by formula ratio, mix with the medical material ethanol extraction of step (1) gained, add spider freeze-drying powder quality 10-30 dissolve with ethanol doubly, cross and filter insoluble matter, sterilizing, obtains spider freeze-drying powder mosquito water of the present invention.
6. the preparation method of a kind of described spider freeze-drying powder mosquito water according to claim 5, is characterized in that: described step (1) reclaims control temperature 40-50 DEG C in ethanol process.
7. the preparation method of a kind of described spider freeze-drying powder mosquito water according to claim 5, is characterized in that: the ethanol contend concentration added in described step (1) and step (2) is 75%-85%.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104997689A (en) * | 2015-07-29 | 2015-10-28 | 江苏奇力康皮肤药业有限公司 | Herbal mosquito-repellent lotion and preparation method thereof |
| CN106333968A (en) * | 2016-08-29 | 2017-01-18 | 梁鹤耀 | Method for preparing freeze-dried spider powder |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1839887A (en) * | 2005-12-22 | 2006-10-04 | 清华大学深圳研究生院 | Spider freeze-drying powder preparation method and its uses in medicine and health product |
| KR100905386B1 (en) * | 2008-12-30 | 2009-06-30 | 주식회사 지씨에이치앤피 | Composition of oriental cosmetics for atopy skin containing herbal extract |
| CN101695469A (en) * | 2009-10-26 | 2010-04-21 | 张发明 | Mosquito dispelling liquid |
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2015
- 2015-01-08 CN CN201510008917.0A patent/CN104758221A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1839887A (en) * | 2005-12-22 | 2006-10-04 | 清华大学深圳研究生院 | Spider freeze-drying powder preparation method and its uses in medicine and health product |
| KR100905386B1 (en) * | 2008-12-30 | 2009-06-30 | 주식회사 지씨에이치앤피 | Composition of oriental cosmetics for atopy skin containing herbal extract |
| CN101695469A (en) * | 2009-10-26 | 2010-04-21 | 张发明 | Mosquito dispelling liquid |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104997689A (en) * | 2015-07-29 | 2015-10-28 | 江苏奇力康皮肤药业有限公司 | Herbal mosquito-repellent lotion and preparation method thereof |
| CN106333968A (en) * | 2016-08-29 | 2017-01-18 | 梁鹤耀 | Method for preparing freeze-dried spider powder |
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