CN109045218B - Yao medicine composition for preventing and treating upper respiratory inflammation and preparation method thereof - Google Patents

Yao medicine composition for preventing and treating upper respiratory inflammation and preparation method thereof Download PDF

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CN109045218B
CN109045218B CN201811249751.1A CN201811249751A CN109045218B CN 109045218 B CN109045218 B CN 109045218B CN 201811249751 A CN201811249751 A CN 201811249751A CN 109045218 B CN109045218 B CN 109045218B
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medicine composition
yao medicine
citronella
mint
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李彤
闫国跃
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Guangxi University of Chinese Medicine
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
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    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

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Abstract

The invention provides a Yao medicine composition for preventing and treating upper respiratory inflammation, which belongs to the technical field of national medicines and comprises radix tinosporae, mint, subprostrate sophora, citronella, lysimachia foenum-graecum hance, radix fici simplicissimae, magnolia flower, leafy bout and rhizoma acori graminei. The effective rate of the Yao medicine composition provided by the invention on upper respiratory tract inflammation is 80-93.33%, and no adverse reaction occurs.

Description

Yao medicine composition for preventing and treating upper respiratory inflammation and preparation method thereof
Technical Field
The invention relates to the technical field of national medicines, and particularly relates to a Yao medicine composition for preventing and treating upper respiratory inflammation and a preparation method thereof.
Background
Pharyngitis (pharyngis) is nonspecific inflammation of pharynx, is a general name of inflammation caused by infection of pharynx by various microorganisms, can exist alone, can coexist with rhinitis, tonsillitis and laryngitis, or is a precursor symptom of certain diseases. Pharyngitis is mainly viral and bacterial infection and is mostly transmitted by droplets or direct contact. The pharynx of human body is the pore canal behind nasal cavity and oral cavity, and can be divided into three parts of nasopharynx, oropharynx and laryngopharynx. The pharynx is rich in lymphoid tissues, and they are collected into masses called tonsils. Just as the pharynx is rich in lymphoid tissues, the pharynx is one of the major portals for the human body to block the invasion of pathogens, especially germs. However, since the throat is complicated in structure and tends to deposit foreign matter such as food residue, bacteria are more likely to stay and multiply in the throat of a person and cause inflammation. In addition, the weakened resistance of the whole body, such as fatigue, catching cold, excessive smoking and drinking, is the cause of the disease. In the prior art, the traditional Chinese medicine composition is used for preventing and treating pharyngitis, but the achieved prevention and treatment effect is not ideal.
Disclosure of Invention
The invention aims to provide a Yao medicine composition for preventing and treating upper respiratory inflammation, which has the effects of detoxifying, relieving sore throat and dredging orifices and can be used for effectively preventing and treating the upper respiratory inflammation.
The invention provides a Yao medicine composition for preventing and treating upper respiratory inflammation, which comprises the following components in parts by weight:
2-30 parts of radix tinosporae, 0.5-10 parts of mint, 1-25 parts of subprostrate sophora, 0.5-15 parts of citronella, 0.5-15 parts of lysimachia foenum-graecum hance, 1-15 parts of hispid fig, 0.5-10 parts of magnolia flower, 1-20 parts of leafy waster and 1-20 parts of rhizoma acori graminei.
Preferably, the composition comprises the following components in parts by weight:
3-25 parts of radix tinosporae, 1-8 parts of mint, 1.5-20 parts of subprostrate sophora, 1.5-10 parts of citronella, 1.5-10 parts of lysimachia foenum-graecum hance, 1.5-10 parts of hispid fig, 1-8 parts of magnolia flower, 2-15 parts of leafy waster and 2-15 parts of rhizoma acori graminei.
Preferably, the composition comprises the following components in parts by weight:
10-20 parts of radix tinosporae, 5-7 parts of mint, 2.5-15 parts of subprostrate sophora, 5-8 parts of citronella, 5-8 parts of lysimachia foenum-graecum hance, 5-8 parts of hispid fig, 2-5 parts of magnolia flower, 5-10 parts of leafy blocks and 5-10 parts of rhizoma acori graminei.
The invention also provides a preparation method of the Yao medicine composition, which comprises the following steps:
mixing the tinospora root, the mint, the subprostrate sophora, the citronella, the lysimachia foenum-graecum hance, the hispid fig root, the magnolia flower, the leafy boulder and the grassleaf sweelflag rhizome, and crushing to obtain crushed substances;
and (4) sieving the obtained crushed material with a 20-mesh sieve or a 80-mesh sieve to obtain the Yao medicine composition.
Preferably, the crushed material further comprises, before sieving: and (3) sequentially baking, disinfecting and sterilizing the crushed materials.
The invention provides a Yao medicine composition for preventing and treating upper respiratory tract inflammation, wherein tinospora root, mint, subprostrate sophora, citronella, lysimachia foenum-graecum and magnolia flower have the effects of clearing away heat and toxic materials, eliminating stagnation and reducing swelling, dispelling wind and clearing, dispelling wind and relieving pain and freeing nasal orifices, and the Yao medicine composition is an insecticide; radix fici simplicissimae and folium fici Pumilae are superficial and have effects of aromatizing, eliminating dampness, invigorating spleen, removing dirt, and relieving exterior syndrome, and are wind medicine; rhizoma Acori Graminei has effects of eliminating dampness, promoting appetite, inducing resuscitation, eliminating phlegm, refreshing mind and improving intelligence, and is used as a medicine for treating wind syndrome. Under the combined action of the medicines, the traditional Chinese medicine composition has the effects of detoxifying, relieving sore throat, dissipating stagnation, reducing swelling, dispelling wind, clearing away heat, dispelling wind, relieving pain, dredging nasal orifice, inducing resuscitation with aromatics, invigorating spleen and eliminating dampness, can detoxify, relieve sore throat and dredge orifice in a short time, and further achieves the effect of efficiently preventing and treating upper respiratory tract inflammation.
The results of the embodiments of the present invention show that: the Yao medicine composition provided by the invention has an effective rate of 80-93.33% on pharyngitis and no adverse reaction.
Detailed Description
The invention provides a Yao medicine composition for preventing and treating upper respiratory inflammation, which comprises the following components in parts by weight:
2-30 parts of radix tinosporae, 0.5-10 parts of mint, 1-25 parts of subprostrate sophora, 0.5-15 parts of citronella, 0.5-15 parts of lysimachia foenum-graecum, 1-15 parts of hispid fig, 0.5-10 parts of magnolia flower, 1-20 parts of leafy waster and 1-20 parts of rhizoma acori graminei; preferably 3 to 25 parts of radix tinosporae, 1 to 8 parts of mint, 1.5 to 20 parts of subprostrate sophora, 1.5 to 10 parts of citronella, 1.5 to 10 parts of lysimachia foenum-graecum, 1.5 to 10 parts of hispid fig, 1 to 8 parts of magnolia flower, 2 to 15 parts of leafy waster and 2 to 15 parts of rhizoma acori graminei; more preferably 10 to 20 parts of radix tinosporae, 5 to 7 parts of mint, 2.5 to 15 parts of subprostrate sophora, 5 to 8 parts of citronella, 5 to 8 parts of lysimachia foenum-graecum, 5 to 8 parts of hispid fig, 2 to 5 parts of magnolia flower, 5 to 10 parts of leafy waster and 5 to 10 parts of grassleaf sweelflag rhizome.
The source of the traditional Chinese medicine is not particularly limited, and the traditional Chinese medicine can be obtained by adopting the conventional commercially available traditional Chinese medicine.
In the present invention, the upper respiratory inflammation includes pharyngitis.
In the invention, the tinospora cordifolia, the mint, the subprostrate sophora, the citronella, the lysimachia foenum-graecum and the magnolia flower have the functions of clearing away heat and toxic materials, eliminating stagnation and reducing swelling, dispelling wind and clearing, dispelling wind and relieving pain and freeing nasal orifices, and are taken as an injection; the radix fici simplicissimae and the barren leaves have the effects of aromatizing, eliminating dampness, invigorating spleen, removing dirt and relieving exterior syndrome, and are wind drugs; the rhizoma Acori Graminei has effects of eliminating dampness, promoting appetite, inducing resuscitation, eliminating phlegm, refreshing mind and improving intelligence, and is used as a medicine for treating wind syndrome.
The invention also provides a preparation method of the Yao medicine composition, which comprises the following steps: mixing the tinospora root, the mint, the subprostrate sophora, the citronella, the lysimachia foenum-graecum hance, the hispid fig root, the magnolia flower, the leafy boulder and the grassleaf sweelflag rhizome, and crushing to obtain crushed substances;
and (4) sieving the obtained crushed material with a 20-mesh sieve or a 80-mesh sieve to obtain the Yao medicine composition.
The conditions for mixing and pulverizing are not particularly limited, and conventional conditions for mixing and pulverizing can be adopted.
In the present invention, the pulverized material before sieving preferably further comprises: and (3) sequentially baking, disinfecting and sterilizing the crushed materials.
The conditions of the baking, the disinfection and the sterilization are not specially limited, and the conventional conditions of the baking, the disinfection and the sterilization of the pharmaceutical composition are adopted.
According to the invention, the crushed material is sieved by a 20-mesh sieve to obtain the Yao medicine composition, and the using method of the Yao medicine composition preferably comprises the following steps: the Yao medicine composition is decocted in water, the obtained water decoction is inhaled by atomization, and the Yao medicine composition is taken once in the morning, at noon and at night, and 7 days is a treatment course.
The invention has no special limit on the mass-to-water volume ratio of the Yao medicine composition, and the Yao medicine composition can be prepared by adopting a conventional method.
In the invention, the time for decocting the water is preferably 20-40 min, more preferably 25-35 min, and most preferably 30 min.
According to the invention, the ground material is sieved by a 80-mesh sieve to obtain the Yao medicine composition, and the using method of the Yao medicine composition preferably comprises the following steps: the Yao medicine composition is inhaled by atomization and is used once in the morning, at noon and at night, and 7 days is a treatment course.
The invention has no special limit on the mass ratio of the Yao medicine composition to the volume ratio of boiled water, and the Yao medicine composition can be prepared by adopting a conventional method.
The Yao medicine composition for preventing and treating upper respiratory inflammation and the preparation method thereof are further described in detail with reference to the following specific examples, and the technical scheme of the invention includes but is not limited to the following examples.
Example 1
Mixing 30g of radix tinosporae, 10g of mint, 25g of subprostrate sophora, 15g of citronella, 15g of lysimachia foenum-graecum, 15g of hispid fig, 10g of flos magnoliae, 20g of leafy boulder and 20g of rhizoma acori graminei, then crushing to obtain crushed materials, screening the crushed materials through a 20-mesh sieve after conventional baking, disinfection and sterilization to obtain a Yao medicine composition, mixing the Yao medicine composition with 1280g of water, then decocting for 30min to obtain a water decoction.
Example 2
Mixing 25g of radix tinosporae, 8g of mint, 15g of subprostrate sophora, 10g of citronella, 10g of lysimachia foenum-graecum, 15g of hispid fig, 8g of flos magnoliae, 15g of leafy boulder and 15g of rhizoma acori graminei, crushing to obtain crushed materials, drying, sterilizing and disinfecting the crushed materials by adopting a conventional method, sieving by a 20-mesh sieve to obtain a Yao medicine composition, mixing the Yao medicine composition with 968g of water, and decocting for 30min to obtain a water decoction.
Example 3
Mixing 20g of radix tinosporae, 5g of mint, 10g of subprostrate sophora, 5g of citronella, 5g of lysimachia foenum-graecum, 10g of hispid fig, 5g of flos magnoliae, 10g of leafy boulder and 10g of rhizoma acori graminei, crushing to obtain crushed materials, screening the crushed materials through a 20-mesh sieve after conventional baking, disinfection and sterilization to obtain a Yao medicine composition, mixing the Yao medicine composition with 640g of water, and then decocting for 30min to obtain a water decoction.
Example 4
Mixing and crushing 3g of radix tinosporae, 1g of mint, 2.5g of subprostrate sophora, 1.5g of citronella, 1.5g of lysimachia foenum-graecum, 1.5g of hispid fig, 1g of flos magnoliae, 2g of leafy boulder and 2g of rhizoma acori graminei to obtain crushed materials, and screening the crushed materials through a 80-mesh sieve after conventional baking, disinfection and sterilization to obtain the Yao medicine composition.
Example 5
Mixing and crushing 2.5g of radix tinosporae, 0.8g of mint, 1.5g of subprostrate sophora, 1g of citronella, 1g of lysimachia foenum-graecum, 1.5g of hispid fig, 0.8g of flos magnoliae, 1.5g of leafy bout and 1.5g of rhizoma acori graminei to obtain crushed materials, and screening the crushed materials through a 80-mesh sieve after conventional baking, disinfection and sterilization to obtain the Yao medicine composition.
Example 6
Mixing 2g of radix tinosporae, 0.5g of mint, 1g of subprostrate sophora, 0.5g of citronella, 0.5g of lysimachia foenum-graecum, 1g of hispid fig, 0.5g of flos magnoliae, 1g of leafy boulder and 1g of rhizoma acori graminei, crushing to obtain a crushed material, and screening the crushed material through a 80-mesh sieve after conventional baking, disinfection and sterilization to obtain the Yao medicine composition.
Example 7
Clinical trial observation is carried out on 90 cases of cases diagnosed as pharyngitis and 15 cases of cases in examples 1 to 6 respectively, wherein the cases are diagnosed in Guangxi Jinxiyao medical hospital, Guangxi Chinese medicinal university, Guangxi International Zhuang medical hospital and Guangxi Chong left city people hospital, and the water decoction is atomized and inhaled in examples 1 to 3, and is taken once in the morning, at noon and evening and 7 days as 1 treatment course for 2 treatment courses. The Yao medicine composition prepared in the embodiment 4-6 is atomized and inhaled once in the morning, at noon and at night, and 7 days are 1 treatment course and are used for 2 treatment courses. Clinical symptoms and laboratory indices were observed after 3 days of withdrawal. Any other therapeutic agents were prohibited during the observation period, and no other non-drug treatment was used, and the results are shown in table 1.
TABLE 1 therapeutic results of Yao medicine composition administration
Treatment of Effective rate (%) Adverse reaction
Example 1 86.67%(13/15) Is free of
Example 2 80.00%(12/15) Is free of
Example 3 86.67%(13/15) Is free of
Example 4 93.33%(14/15) Is free of
Example 5 93.33%(14/15) Is free of
Example 6 80.00%(12/15) Is free of
Total 90 86.67%(78/90) Is free of
According to the table 1, the effective rate of the Yao medicine composition on pharyngitis is 80% -93.33%, and no adverse reaction occurs.
Therefore, the effective rate of the Yao medicine composition on pharyngitis is 80-93.33%, and the pharyngitis can be effectively prevented and treated.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (5)

1. The Yao medicine composition for preventing and treating pharyngitis is characterized by comprising the following components in parts by weight:
2-30 parts of radix tinosporae, 0.5-10 parts of mint, 1-25 parts of subprostrate sophora, 0.5-15 parts of citronella, 0.5-15 parts of lysimachia foenum-graecum hance, 1-15 parts of hispid fig, 0.5-10 parts of magnolia flower, 1-20 parts of leafy waster and 1-20 parts of rhizoma acori graminei.
2. The Yao medicine composition of claim 1, wherein the Yao medicine composition is characterized by comprising the following components in parts by weight:
3-25 parts of radix tinosporae, 1-8 parts of mint, 1.5-20 parts of subprostrate sophora, 1.5-10 parts of citronella, 1.5-10 parts of lysimachia foenum-graecum hance, 1.5-10 parts of hispid fig, 1-8 parts of magnolia flower, 2-15 parts of leafy waster and 2-15 parts of rhizoma acori graminei.
3. The Yao medicine composition of claim 1 or 2, which is characterized by comprising the following components in parts by weight:
10-20 parts of radix tinosporae, 5-7 parts of mint, 2.5-15 parts of subprostrate sophora, 5-8 parts of citronella, 5-8 parts of lysimachia foenum-graecum hance, 5-8 parts of hispid fig, 2-5 parts of magnolia flower, 5-10 parts of leafy blocks and 5-10 parts of rhizoma acori graminei.
4. The preparation method of the Yao medicine composition of any one of claims 1-3, comprising the following steps:
mixing the tinospora cordifolia, the mint, the subprostrate sophora, the citronella, the lysimachia foenum-graecum hance, the hispid fig, the magnolia flower, the leafy boulder and the grassleaf sweelflag rhizome of any one of claims 1 to 3, and crushing to obtain a crushed material;
and (4) sieving the obtained crushed material with a 20-mesh sieve or a 80-mesh sieve to obtain the Yao medicine composition.
5. The method of claim 4, wherein the comminuted material further comprises, prior to sieving: and (3) sequentially baking, disinfecting and sterilizing the crushed materials.
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768413A (en) * 2012-10-19 2014-05-07 李征 Traditional Chinese medicinal prescription for treating acute pharyngitis
CN106473268A (en) * 2016-08-17 2017-03-08 成都柏图生物科技有限公司 A kind of pre- anti-virus, Herb medicine gauze mask of allergic rhinitis and its production and use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768413A (en) * 2012-10-19 2014-05-07 李征 Traditional Chinese medicinal prescription for treating acute pharyngitis
CN106473268A (en) * 2016-08-17 2017-03-08 成都柏图生物科技有限公司 A kind of pre- anti-virus, Herb medicine gauze mask of allergic rhinitis and its production and use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
中药雾化吸入对咽炎的治疗体会;朱海玲等;《齐齐哈尔医学院学报》;20091231;第30卷(第6期);708 *
咽喉病见症选药;耿鉴庭等;《陕西新医药》;19781231(第4期);26-27 *

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