CN103860750B - A kind of Chinese medicine preparation for the treatment of epilepsy - Google Patents

A kind of Chinese medicine preparation for the treatment of epilepsy Download PDF

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CN103860750B
CN103860750B CN201410144660.7A CN201410144660A CN103860750B CN 103860750 B CN103860750 B CN 103860750B CN 201410144660 A CN201410144660 A CN 201410144660A CN 103860750 B CN103860750 B CN 103860750B
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herba
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hour
achyranthis asperae
epilepsy
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CN103860750A (en
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况磊
刘海英
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Jiangsu Bloomer Investment Co Ltd
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Abstract

The invention discloses a kind of Chinese medicine preparation for the treatment of epilepsy, preparation method is: Herba Strigae Asiaticae, PINGDIMU, Herba Epimeredis Indicae, Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Codonopsis lanceolatae, Fructus Leonuri, Fructus Perillae Frutescentis, Herba Centipedae are put into drug-decocting appliance, add the clean water meeting drinking water standard, amount of water, to exceed powder 2-3cm for degree, soaks half an hour; Slow fire boiling half an hour is used again instead after boiling with high heat; Carnis Haliotidis is gilled and adds in drug-decocting appliance after cleaning up and continue slow fire boiling half an hour, removing medicinal residues, get decoction.Compared with prior art, good effect, short treating period, side effect is little, easy to use, cost is low in the present invention, and the present invention passes through long felt, in conjunction with experience among the people, develop the active component extracted from natural animal-plant compositions, safe and reliable, have no side effect.

Description

A kind of Chinese medicine preparation for the treatment of epilepsy
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine preparation for the treatment of epilepsy.
Background technology
Epileptics is a kind of global commonly encountered diseases, frequently-occurring disease, and current global patient reaches more than 7,000 ten thousand people, wherein more than China patient about 9,000,000 people.Epilepsy is commonly called as " sheep is insane crazy ", " epilepsy ", have local title " shading crazy " etc., also usually by popular being called " convulsion " of people.Epilepsy refers to that abnormal and excessive supersynchronousization of brain neuron is discharged the clinical picture caused.Be characterized in unexpected and transient symptom, because the neuron position in the brain of paradoxical discharge is different, and have the diversified form of expression.Generally realize during morbidity and all lose, eyes upwards turn over, and spit out white foams, loss of consciousness, and that exhales does not answer, and gatism, can bite tongue sometimes, take out rear many sleeps.Convulsion general persistence is not long, at least a few second, several minutes at most, is generally no more than 15 minutes, and severe patient can be twitched repeatedly repeatedly, or lasting several tens minutes is more than, is called status epilepticus.Epileptics is a kind of chronic persistent ailment, the title that the state of an illness is complicated, touching difficulty heals, has " not completely annihilated disease ".
Because the cause of disease is complicated, recurrent exerbation, be difficult to radical cure, epileptics causes the misery on great body & mind to patient and household thereof.Current treatment epileptics mainly uses Western medicine and operation, and Western medicine is as phenytoin Sodium, sodium valproate, carbamazepine, clonazepam etc.Western medicine can of short duration elimination symptom, and delays the time that symptom occurs again.But it brings serious side effect simultaneously, Western medicine of taking as usual easily causes cerebellar syndrome, and dystropy is drowsiness, dull expression, hypomnesis, the psychological problem such as aggressive behavior and anxiety.Western medicine also has damage in various degree to liver, shows as Nausea and vomiting, appetite declines, unable etc.In addition, use the western medicine epileptics length course for the treatment of, weak curative effect, dependency is strong, medical expense is high.
Summary of the invention
In order to make up the deficiencies in the prior art, the invention provides the Chinese medicine preparation of a kind of good effect, short treating period, side effect is little, easy to use, cost is low treatment epilepsy.Realize particular by following technical scheme:
A kind of Chinese medicine preparation preparation method for the treatment of epilepsy is: take Carnis Haliotidis 20 ~ 50 weight portion, Herba Strigae Asiaticae 5 ~ 10 weight portion, PINGDIMU 5 ~ 10 weight portion, Herba Epimeredis Indicae 5 ~ 10 weight portion, Radix achyranthis asperae (Herba Achyranthis Asperae) 5 ~ 10 weight portion, Radix Codonopsis lanceolatae 5 ~ 10 weight portion, Fructus Leonuri 5 ~ 10 weight portion, Fructus Perillae Frutescentis 5 ~ 10 weight portion, Herba Centipedae 5 ~ 10 weight portion; Above-mentioned Herba Strigae Asiaticae, PINGDIMU, Herba Epimeredis Indicae, Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Codonopsis lanceolatae, Fructus Leonuri, Fructus Perillae Frutescentis, Herba Centipedae are put into drug-decocting appliance, adds the clean water meeting drinking water standard, amount of water, to exceed powder 2-3cm for degree, soaks half an hour; Slow fire boiling half an hour is used again instead after boiling with high heat; Carnis Haliotidis is gilled and adds in drug-decocting appliance after cleaning up and continue slow fire boiling half an hour, removing medicinal residues, get decoction.
Therapeutic Method: every day potion, take at twice; Take treatment continuously 30 days.
Drug action mechanism of the present invention is as follows:
Carnis Haliotidis: the monoshell Mollusca in ocean, only have demifacet shell, shell heavily fortified point is thick, flat and wide, some ear as people of shape, so be also its " extra large ear ".Carnis Haliotidis is nutritious, containing protein, and fat, the iodine of saccharide and needed by human, calcium, phosphorus, ferrum and multivitamin etc.Carnis Haliotidis has YIN nourishing, dietetic therapy effect of balancing blood pressure and nourishing skin care.Also the composition of " Bao Su " is called as containing one in Bao flesh of fish, can the growth of anticancer, so have anticancer effect.Abalone shells can be used as medicine, and is commonly called as Concha Haliotidis, and ancient book is again its Herba Senecionis Scandentis, has effect of improving eyesight, also has the curative effect of purging liver-heat, YIN nourishing and YANG strengthening.
Herba Strigae Asiaticae: [another name] infantile malnutrition grass.The herb of [source] goatweed Herba Lobeliae Chinensis.[meridian distribution of property and flavor] property is put down, sweet in the mouth, light.Return kidney channel, spleen channel, Liver Channel.[effect and effect] suppressing the hyperactive liver disappears infantile malnutrition, strengthening the spleen to promote digestion, clearing away heat and promoting diuresis.Belong to the heat clearing and fire purging medicine of antipyretic subordinate classification.Certain curative effect is had to diarrhoea, hepatitis.[clinical practice] consumption 9 ~ 15 grams, decoction.With controlling infantile malnutrition, child dyspepsia caused by overeating poor appetite diarrhoea, general edema with yellowish skin, nyctalopia.
PINGDIMU: [another name] Herba Ardisiae Japonicae, YEXIAHONG, Radix Phyllagathis fordii, old not large.The Herb of [source] Myrsinacea plant Herba Ardisiae Japonicae.[meridian distribution of property and flavor] property is put down, bitter in the mouth, pungent.Return lung meridian, Liver Channel.[effect and effect] antitussive, eliminate the phlegm, invigorate blood circulation, diuresis, removing toxic substances.Belong to the medicine for the treatment of cough and asthma under expectorant cough suppressant and anti-asthmatic classification.Mainly there is cough-relieving, eliminating phlegm and relieving asthma, antibacterial and antivirus action.With controlling chronic tracheitis, pulmonary tuberculosis cough spitting of blood, spit blood, de-power impairment caused by overstrain, muscles and bones are ached, hepatitis, dysentery, acute and chronic nephritis, hypertension, hernia, toxic swelling.In addition, the effect reducing rat trachea one lung tissue oxygen consumption is also had.[clinical practice] consumption 9 ~ 12 grams, decoction; Or smash juice.External: smash deposited.
Herba Epimeredis Indicae: [another name] native Radix Saposhnikoviae, smear grass, dirty grass, clothing of failing, false Folium Perillae, horsecloth leaf, Herba Siegesbeckiae, four square-stems, Herba rutae, smelly Radix Perillae, duck are slightd, large thin bamboo strip grass, llama is ancient disturbs.The aerial parts of the wide Radix Saposhnikoviae of [source] labiate.[meridian distribution of property and flavor] is warm in nature, acrid in the mouth, hardship.Gui Jing is vacant.[effect and effect] dispels the wind, dehumidify, detoxify, pain relieving.Belong to the pungent and warm medicine for relieving the exterior syndrome of diaphoretic medicine subordinate classification.[clinical practice] consumption 9 ~ 15 grams, decoction; Suitable amount used externally, decoct wash or smash deposited.By the fever of the body that cures cold, vomiting, stomachache, bones and muscles pain, skin infection, eczema.
Radix achyranthis asperae (Herba Achyranthis Asperae): [another name] barb grass, agnail are careless, Blainvillea acmell. (L.) Philipson..The herb of [source] amaranthaceous plant Radix Achyranthis.[meridian distribution of property and flavor] is cold in nature, sweet in the mouth, light.Return lung meridian, urinary bladder channel, Liver Channel.[effect and effect] heat clearing away of inducing sweat, relieving stranguria by diuresis, promoting blood circulation to remove blood stasis.Belong to the stranguria-relieving diuretic of damp-clearing drug subordinate classification, have inhibitory action to diphtheria corynebacterium, and in having and the effect of diphtheria corynebacterium toxin; Saponin contained by seed obviously can strengthen isolated frog heart, Cor Leporis, the Cavia porcellus heart and Cor Leporis contractility in place; Back-off potash has the effect of blood pressure lowering, decreased heart rate, blood vessel dilating, increase respiratory frequency and amplitude to Canis familiaris L..[clinical practice] consumption 9 ~ 15 grams, decoction; Fresh goods consumption 50 ~ 100 grams.External: decoct washing or smash deposited.With the heating that cures cold, summer-heat headache, damp-warm diseases heat of a specified duration do not move back, malaria alternate attack of chill and fever, laryngopharynx swelling and pain, mumps, pyretic stranguria, edema; Also can be used for preventing and treating influenza, treating swelling and pain by traumatic injury is controlled in external.
Radix Codonopsis lanceolatae: [another name] Lac caprae seu ovis, Radix Rehmanniae, Radix Codonopsis Lanceolatae.The root of [source] Campanulaceae Lac caprae seu ovis.[meridian distribution of property and flavor] is warm in nature, sweet in the mouth.Return spleen channel, lung meridian.[effect and effect] lactogenesis of enriching blood, heat-clearing and toxic substances removing, detumescence and apocenosis.Belong to the heat and toxic materials clearing away medicine under antipyretic classification.[clinical practice] consumption 15 ~ 30 grams; Suitable amount used externally, decocts washing.With body void, hypogalactia, carbuncle sore tumefacting virus, mastitis etc. after curing the disease.
Fructus Leonuri: [another name] Herba Leonuri, the beautiful son of punching, FRUCTUS LEONURI, Fructus Leonuri, Herba vallisneriae Spiralis.The fruit of [source] labiate Herba Leonuri.[meridian distribution of property and flavor] cold nature, acrid in the mouth, hardship.Return pericardium channel, Liver Channel.[effect and effect] promoting blood flow to regulate menstruation, liver heat removing and eyesight improving.Belong to the blood-activating and menstruation-regulating medicinal under drug for invigorating blood circulation and eliminating stasis classification.[clinical practice] consumption 5 ~ 10 grams.With diseases such as treating the liver heat headache, conjunctival congestion and swelling pain.
Fructus Perillae Frutescentis: [another name] weak son, FRUCTUS PERILLAE AIBA.The mature fruit of [source] labiate common perilla.[meridian distribution of property and flavor] is warm in nature, acrid in the mouth.Return lung meridian, large intestine channel.[effect and effect] therapeutic method to keep the adverse QI flowing downwards expectorant, loosening bowel to relieve constipation.Belong to the laxative drug under purgatives medicine classification.[clinical practice] consumption 5 ~ 10 grams.With controlling cough with dyspnea, phlegm dyspnea, dryness of the intestine constipation.
Herba Centipedae: [another name] Myriogyne minuta, Fructus Piperis, three bud halberds.The herb of [source] feverfew Herba Centipedae.[meridian distribution of property and flavor] is warm in nature, acrid in the mouth.Return lung meridian, Liver Channel.[effect and effect] clearing the nasal passage, cough-relieving.The pungent and warm medicine for relieving the exterior syndrome of classifying under belonging to diaphoretic medicine.[clinical practice] consumption 3 ~ 10 grams; Fresh goods doubles, and smashes juice and takes available to 60 grams; Suitable amount used externally.With the disease controlling the nasal obstruction of affection of exogenous wind-cold, watery nasal discharge, headache; Have a stuffy nose obstructed; Cold-phlegm cough with asthma, pertussis; Multiple pain disease and the tinea skin ulcer prurituss such as wind syndrome of head pain, toothache, trauma pain, rheumatic arthralgia, sore, carbuncle and painful swelling, acute filthy disease and dysentery stomachache.
Chinese medicine preparation of the present invention has eliminates phlegm for resuscitation, and relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion, spleen benefiting and stimulating the appetite, the function of benefiting essence and marrow.Chinese medicine preparation of the present invention cures mainly epilepsy; What applicable epilepsy caused faints suddenly, slobbering, gnathospasma, words of breaking by the teeth, platycoria, the eyes turning upwards, incontinence of urination and defecation, tic of the limbs, or the cry etc. sending similar pig sheep in mouth, feel more tired after waking up from head to foot, just like ordinary person, often show effect, unconsciousness Chu during outbreak.
The Chinese medicine preparation beneficial effect for the treatment of epilepsy of the present invention is: good effect, short treating period, side effect is little, easy to use, cost is low, the present invention passes through long felt, in conjunction with experience among the people, develop the active component extracted from natural animal-plant compositions, safe and reliable, have no side effect.
Detailed description of the invention
Embodiment 1:
Take Carnis Haliotidis 20g, Herba Strigae Asiaticae 10g, PINGDIMU 5g, Herba Epimeredis Indicae 10g, Radix achyranthis asperae (Herba Achyranthis Asperae) 5g, Radix Codonopsis lanceolatae 10g, Fructus Leonuri 5g, Fructus Perillae Frutescentis 10g, Herba Centipedae 5g; Above-mentioned Herba Strigae Asiaticae, PINGDIMU, Herba Epimeredis Indicae, Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Codonopsis lanceolatae, Fructus Leonuri, Fructus Perillae Frutescentis, Herba Centipedae are put into drug-decocting appliance, adds the clean water meeting drinking water standard, amount of water, to exceed powder 2-3cm for degree, soaks half an hour; Slow fire boiling half an hour is used again instead after boiling with high heat; Gilled by Carnis Haliotidis and add in drug-decocting appliance after cleaning up and continue slow fire boiling half an hour, removing medicinal residues, get the Chinese medicine preparation that namely decoction obtains treatment epilepsy.
Embodiment 2:
Take Carnis Haliotidis 50g, Herba Strigae Asiaticae 5g, PINGDIMU 10g, Herba Epimeredis Indicae 5g, Radix achyranthis asperae (Herba Achyranthis Asperae) 10g, Radix Codonopsis lanceolatae 5g, Fructus Leonuri 10g, Fructus Perillae Frutescentis 5g, Herba Centipedae 10g; Above-mentioned Herba Strigae Asiaticae, PINGDIMU, Herba Epimeredis Indicae, Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Codonopsis lanceolatae, Fructus Leonuri, Fructus Perillae Frutescentis, Herba Centipedae are put into drug-decocting appliance, adds the clean water meeting drinking water standard, amount of water, to exceed powder 2-3cm for degree, soaks half an hour; Slow fire boiling half an hour is used again instead after boiling with high heat; Gilled by Carnis Haliotidis and add in drug-decocting appliance after cleaning up and continue slow fire boiling half an hour, removing medicinal residues, get the Chinese medicine preparation that namely decoction obtains treatment epilepsy.
Embodiment 3:
Take Carnis Haliotidis 35g, Herba Strigae Asiaticae 8g, PINGDIMU 8g, Herba Epimeredis Indicae 7g, Radix achyranthis asperae (Herba Achyranthis Asperae) 7g, Radix Codonopsis lanceolatae 7g, Fructus Leonuri 7g, Fructus Perillae Frutescentis 7g, Herba Centipedae 7g; Above-mentioned Herba Strigae Asiaticae, PINGDIMU, Herba Epimeredis Indicae, Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Codonopsis lanceolatae, Fructus Leonuri, Fructus Perillae Frutescentis, Herba Centipedae are put into drug-decocting appliance, adds the clean water meeting drinking water standard, amount of water, to exceed powder 2-3cm for degree, soaks half an hour; Slow fire boiling half an hour is used again instead after boiling with high heat; Gilled by Carnis Haliotidis and add in drug-decocting appliance after cleaning up and continue slow fire boiling half an hour, removing medicinal residues, get the Chinese medicine preparation that namely decoction obtains treatment epilepsy.
Clinical data:
To Anhui 300, routine epileptic carries out clinical observation treatment, wherein male 161 example, women 139 example, 24 to 61 years old ages, 41 years old mean age.Be divided into 3 treatment groups immediately, often organize 100 people, treatment group 1 adopts the lotion for treatment of embodiment 1; Treatment group 2 adopts the lotion for treatment of embodiment 2; Treatment group 3 adopts the lotion for treatment of embodiment 3.
(1) Therapeutic Method:
Every day, potion, took at twice; Take treatment continuously 30 days.
(2) efficacy assessment standard: with reference to the evaluation of clinical curative effect standard on probation of antiepileptic (Western medicine) ordered by 1979 Qingdao meetings, point level Four evaluation.
Effective: after medication, epilepsy controls, or attack times comparatively front minimizing more than 75% for the treatment of in same period, and during outbreak, symptom and persistent period all obviously alleviate and shorten, and electroencephalogram improves.
Effective: after medication, epilepsy number of times comparatively reduces 50% ~ 75% before treatment in same period, and there be alleviating and shortening in various degree outbreak symptom and persistent period, and electroencephalogram slightly improves.
Heterodyne: after medication, comparatively the front minimizing for the treatment of is less than 50% in same period for epilepsy number of times, and outbreak symptom and time are not improved, and electroencephalogram is unchanged.
Invalid: after medication, the number of times, clinical symptoms etc. of epilepsy are all unchanged, even trend is serious.
(3) therapeutic effect:
Treatment group 1: effective 69 examples, account for 69%; Effective 31 examples, account for 31%; Heterodyne 0 example; Invalid 0 example; Total effective rate 100%;
Treatment group 2: effective 93 examples, account for 93%; Effective 7 examples, account for 7%; Heterodyne 0 example; Invalid 0 example; Total effective rate 100%;
Treatment group 3: effective 78 examples, account for 78%; Effective 21 examples, account for 21%; Heterodyne 1 example, accounts for 1%; Invalid 0 example; Total effective rate 99%.
The above, be only preferred embodiment of the present invention, be not intended to limit protection scope of the present invention.One skilled in the art will appreciate that protection scope of the present invention is as the criterion with appending claims.

Claims (1)

1. treat a Chinese medicine preparation for epilepsy, it is characterized in that preparation method is: take Carnis Haliotidis 20 ~ 50 weight portion, Herba Strigae Asiaticae 5 ~ 10 weight portion, PINGDIMU 5 ~ 10 weight portion, Herba Epimeredis Indicae 5 ~ 10 weight portion, Radix achyranthis asperae (Herba Achyranthis Asperae) 5 ~ 10 weight portion, Radix Codonopsis lanceolatae 5 ~ 10 weight portion, Fructus Leonuri 5 ~ 10 weight portion, Fructus Perillae Frutescentis 5 ~ 10 weight portion, Herba Centipedae 5 ~ 10 weight portion; Above-mentioned Herba Strigae Asiaticae, PINGDIMU, Herba Epimeredis Indicae, Radix achyranthis asperae (Herba Achyranthis Asperae), Radix Codonopsis lanceolatae, Fructus Leonuri, Fructus Perillae Frutescentis, Herba Centipedae are put into drug-decocting appliance, adds the clean water meeting drinking water standard, amount of water, to exceed powder 2-3cm for degree, soaks half an hour; Slow fire boiling half an hour is used again instead after boiling with high heat; Carnis Haliotidis is gilled and adds in drug-decocting appliance after cleaning up and continue slow fire boiling half an hour, removing medicinal residues, get decoction.
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CN103142759A (en) * 2013-03-25 2013-06-12 威海康博尔生物药业有限公司 Oral liquid capable of complementing vital essence and tonifying Qi and nourishing blood and tranquilization

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