CN103948750A - Traditional Chinese medicine preparation comprising sea cucumber composition and used for treating epilepsy - Google Patents
Traditional Chinese medicine preparation comprising sea cucumber composition and used for treating epilepsy Download PDFInfo
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Abstract
The invention discloses an externally-applied traditional Chinese medicine preparation comprising a sea cucumber composition and used for treating epilepsy. A preparation method of the traditional Chinese medicine preparation comprises: putting folium isatidis, bryophyllum pinnatum, herba artemisiae anomalae, Chinese iris seed, humulus iupulus, isatis root, raspberry and folium rhododendri daurici into a medicine decocting utensil, adding clean water according with life drinking water standard to enable exceed medicine surface by 2-3 cm, and immersing for half an hour; boiling with strong fire, then decocting with slow fire for half an hour; and gilling sea cucumber, cleaning, adding into the medicine decocting utensil, continuing to decoct with slow fire for half an hour, removing decoction dregs and getting the decoction. Compared with the prior art, the traditional Chinese medicine preparation has the advantages of good treatment effect, small treatment course, small side effect, usage convenience and low cost. According to the traditional Chinese medicine preparation, through long-term exploration and combining with folk experiences, the method is developed for extracting active compositions from natural animals and plants, and the prepared traditional Chinese medicine preparation is safe and reliable to use and free of toxic and side effects.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine preparation of the treatment epilepsy that contains Stichopus japonicus composition.
Background technology
Epileptics is a kind of global commonly encountered diseases, frequently-occurring disease, and current global patient reaches more than 7,000 ten thousand people, wherein more than China patient approximately 9,000,000 people.Epilepsy is commonly called as " sheep is insane crazy ", " epilepsy ", has local title " shading crazy " etc., also usually by popular being called of people " convulsion ".Epilepsy refers to abnormal and excessive supersynchronousization of the brain neuron clinical picture causing that discharges.Be characterized in suddenly and one cross property symptom due to the neuron of the paradoxical discharge position difference in brain, and have the diversified form of expression.When morbidity, general consciousness is all lost, and eyes upwards turn over, spit out white foams, and loss of consciousness, that exhales does not answer, and gatism, can bite tongue sometimes, takes out rear fall asleep more.Convulsion general persistence is not long, several seconds at least, and several minutes at most, be generally no more than 15 minutes, severe patient can be twitched repeatedly repeatedly, or continues tens of minutes incessantly, is called status epilepticus.Epileptics is a kind of chronic persistent ailment, and state of an illness complexity, touching difficulty heal, have the title of " not completely annihilated disease ".
Due to cause of disease complexity, outbreak repeatedly, is difficult to radical cure, and epileptics has caused the misery on great body & mind to patient and household thereof.Treatment epileptics is mainly used Western medicine and operation at present, and Western medicine is as phenytoin Sodium, sodium valproate, carbamazepine, clonazepam etc.Western medicine can of short duration elimination symptom, and delays the time that symptom occurs again.But it has brought serious side effect simultaneously, the Western medicine of taking as usual easily causes cerebellar syndrome, and dystropy is drowsiness, dull expression, hypomnesis, the psychological problems such as aggressive behavior and anxiety.Western medicine also has damage in various degree to liver, show as nauseating, vomiting, appetite decline, unable etc.In addition, use the western medicine epileptics length course for the treatment of, weak curative effect, dependency is strong, medical expense is high.
Summary of the invention
In order to make up the deficiencies in the prior art, the invention provides the Chinese medicine preparation of a kind of good effect, short treating period, side effect is little, easy to use, cost is low treatment epilepsy.Specifically be achieved by the following technical solution:
A kind of Chinese medicine preparation preparation method of the treatment epilepsy that contains Stichopus japonicus composition is: take Stichopus japonicus 5 ~ 10 weight portions, Folium Isatidis 5 ~ 30 weight portions, Herba Bryophylli Pinnati 5 ~ 30 weight portions, Herba Artemisiae Anomalae 5 ~ 30 weight portions, Semen Iridis 5 ~ 30 weight portions, Flos lupuli (Flos Humuli Lupuli) 5 ~ 30 weight portions, Radix Isatidis 5 ~ 30 weight portions, Fructus Rubi 5 ~ 30 weight portions, Folium Rhododendri Daurici 5 ~ 30 weight portions; Above-mentioned Folium Isatidis, Herba Bryophylli Pinnati, Herba Artemisiae Anomalae, Semen Iridis, Flos lupuli (Flos Humuli Lupuli), Radix Isatidis, Fructus Rubi, Folium Rhododendri Daurici are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction.
Therapeutic Method: every day potion, take at twice; Take continuously treatment 30 days.
Drug action mechanism of the present invention is as follows:
Stichopus japonicus: Echinodermata, Holothuroidea, the common name of Holothuroidea animal, is important oceanic invertebrate.Sea cucumber nutrient is abundant, and body contains the compositions such as protein, fat, vitamin, various trace elements, colloid, holotoxin, acid mucopolysaccharide, but not containing cholesterol.Qing Dynasty's supplementary Amplifications of the Compendium of Materia Medica Chinese medicine ancient books and records record " Stichopus japonicus benefit warm in nature, sufficient enemy joins therefore named Stichopus japonicus; Sweet-salty, the kidney invigorating warp, beneficial marrow, expectorant is prolonged, and takes the photograph urine, flaccidity is treated in tonifying YANG, kills skin ulcer worm ".Successively there is in recent years the traditional Chinese medical science to propose Stichopus japonicus alone or prescription therapeutic tumor, aplastic anemia and diabetes, obtain good result, assisting a ruler in governing a country as commonly encountered diseases treatments such as epilepsy, gastric and duodenal ulcers, chronic viral hepatitis B hepatitis, chronic nephritis, hypertension, pulmonary tuberculosis, neurasthenia's phlebothrombosis, hemorrhoid, proctoptosis and constipation simultaneously, and for general after being ill or in the various medicated diet or diet therapy formulation worked out in postpartum recovery process, Stichopus japonicus has all obtained admitting widely and applying.
Folium Isatidis: [another name] roadside Folium Isatidis.The leaf of [source] Verbenaceae Herba Diclipterae Chinensis.[meridian distribution of property and flavor] is cold in nature, bitter in the mouth.GUIXIN warp, stomach warp.[effect and effect] heat-clearing and toxic substances removing, the clear speckle of removing heat from blood.Belong to the heat and toxic materials clearing away medicine of classifying under antipyretic.10 ~ 15 grams of [clinical practice] decoctions.With controlling that epidemic febrile disease, heat in blood send out that speckle, high fever do not move back and the top hemorrhage of bleeding due to blood-heat etc.[main component], containing flavonoid glycoside one mountain cyrtophyllin, has diuresis to rat, and rat Ovum Gallus domesticus album " arthritis " and dextran " arthritis " are all had to obvious antiinflammatory action.In addition, also contain indigo Magnolia denudata, the composition such as indigo.
Herba Bryophylli Pinnati: [another name] DABUSI, foot order grass, Herba Senecionis Chrysanthemoidis.The herb of [source] crassulaceae plants Herba Bryophylli Pinnati.[meridian distribution of property and flavor] is cold in nature, the micro-acid of taste, puckery.Return lung meridian, kidney channel.[effect and effect] removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, removing toxic substances and promoting tissue regeneration.Belong to the blood-cooling hemostatic of classifying under hemorrhage.15 ~ 30 grams of [clinical practice] consumptions.With controlling laryngopharynx swelling and pain, hot stomachache, diarrhea of heat type hematodiarrhoea, hemoptysis, haematemesis, acute catarrhal conjunctivitis, otitis media, carbuncle furunculosis, acute mastitis, burn due to hot liquid or fire, traumatic hemorrhage etc.
Herba Artemisiae Anomalae: [another name] golden JINU, spend tail, charcoal charcoal bag in vain.The aerial parts of [source] feverfew artemisia anomalas.[meridian distribution of property and flavor] is warm in nature, acrid in the mouth, micro-hardship.GUIXIN warp, Liver Channel, spleen channel.[effect and effect] promoting blood circulation to restore menstrual flow, removing food stagnancy, pain relieving.Belong to the blood-activating and menstruation-regulating medicinal of classifying under drug for invigorating blood circulation and eliminating stasis.3 ~ 10 grams of [clinical practice] consumptions.With controlling amenorrhea due to stagnation of blood, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal; Traumatic injury, blood stasis swell and ache; Food stagnation dysentery, hemorrhoid, have blood in stool.In addition, existing still obstructed with controlling cirrhotic ascites, urinary system calculus, prostate hyperplasia, dysuria or drop.
Semen Iridis: [another name] litchi reality, horse chinaberry, horse Semen Nelumbinis.The mature seed of [source] irides Chinese small iris.[meridian distribution of property and flavor] property is flat, sweet in the mouth.Return Liver Channel, stomach warp, spleen channel, lung meridian.[effect and effect] clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating, hemostasis.Belong to the blood-cooling hemostatic of classifying under hemorrhage.5 ~ 10 grams of [clinical practice] consumptions, soup treatment icterohepatitis, dysentery, haematemesis, epistaxis, metrorrhagia, leucorrhea, pharyngitis, carbuncle, the colic decocted for oral administration.Suitable amount used externally is smash deposited.Treatment bone tuberculosis: Semen Iridis is put fried dry levigation in iron pan, for oral administration, every day 3 times, each 5.7 grams, children's is cut down according to the circumstance.
Flos lupuli (Flos Humuli Lupuli): [another name] hops, Flos lupuli, Flos Lupuli (Hops).The female inflorescence of [source] moraceae plants Flos lupuli (Flos Humuli Lupuli).[meridian distribution of property and flavor] slightly cool in nature, bitter in the mouth; Nontoxic.Return Liver Channel, stomach warp.[effect and effect] invigorating the stomach and promoting digestion, diuresis are calmed the nerves.Belong to digestants.1.5 ~ 5 grams of [clinical practice] consumptions, soup or the soaked tea-drinking of working as decocted for oral administration, treatment dyspepsia, abdominal distention, edema, cystitis, pulmonary tuberculosis, insomnia.
Radix Isatidis: [another name] northern Radix Isatidis, indigo-blue, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait) root.The root of [source] cruciferae isatis.[meridian distribution of property and flavor] is cold in nature, bitter in the mouth.GUIXIN warp, stomach warp.[effect and effect] heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.Belong to the heat and toxic materials clearing away medicine of classifying under antipyretic.9 ~ 15 grams of [clinical practice] consumptions.With controlling, influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, pyretic toxicity are sent out speckle, coma is told nosebleed, pharyngeal swelling, mumps, skin ulcer rash etc.
Fructus Rubi: [another name] covers the aggregate fruit of basin, little pallet [source] rosaceous plant rubus chingii Hu.[meridian distribution of property and flavor] is warm in nature, sweet in the mouth, acid.Return kidney channel, urinary bladder channel.[effect and effect] kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination.Belong to the controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping medicine of classifying under astringent medicinal.6 ~ 12 grams of [clinical practice] consumptions.With controlling seminal emission, spermatorrhea, the enuresis, the frequent micturition of suffering from a deficiency of the kidney due to not consolidating; The poor vision of deficiency of the liver and kindey etc.
Folium Rhododendri Daurici: [another name] Rhododendron simsii Planch., Folium Rhododendri Mucronulati, Jin Dalai.The leaf of [source] ericad Folium Cuculus polioephalus.[meridian distribution of property and flavor] is warm in nature, acrid in the mouth, hardship.Return lung meridian.[effect and effect] cough-relieving, eliminate the phlegm.9 ~ 15 grams of [clinical practice] consumptions, take orally and decoct soup, treat acute and chronic bronchitis.Fresh goods doubles.Points for attention: can have xerostomia, feel sick, the neurological symptom such as vomiting, but degree is slight.Part patient can occur heart rate slowly, blood pressure drops etc.Hepatopath is cautious use of.
Chinese medicine preparation of the present invention has eliminates phlegm for resuscitation, the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., spleen benefiting and stimulating the appetite, the function of benefiting essence and marrow.Chinese medicine preparation of the present invention cures mainly epilepsy; What applicable epilepsy caused faints suddenly, slobbering, gnathospasma, the words of breaking by the teeth, platycoria, the eyes turning upwards, incontinence of urination and defecation, tic of the limbs, or mouthful in send the cry etc. of similar pig sheep, after waking up, feel more from head to foot tired, just like ordinary person, outbreak often, unconsciousness Chu when outbreak.
The Chinese medicine preparation beneficial effect for the treatment of epilepsy of the present invention is: good effect, short treating period, side effect is little, easy to use, cost is low, the present invention is by long-term exploration, in conjunction with experience among the people, develop the active component extracting from natural animal-plant compositions, safe and reliable, have no side effect.
Detailed description of the invention
Embodiment 1:
Take Stichopus japonicus 5g, Folium Isatidis 30g, Herba Bryophylli Pinnati 5g, Herba Artemisiae Anomalae 30g, Semen Iridis 5g, Flos lupuli (Flos Humuli Lupuli) 30g, Radix Isatidis 5g, Fructus Rubi 30g, Folium Rhododendri Daurici 5g; Above-mentioned Folium Isatidis, Herba Bryophylli Pinnati, Herba Artemisiae Anomalae, Semen Iridis, Flos lupuli (Flos Humuli Lupuli), Radix Isatidis, Fructus Rubi, Folium Rhododendri Daurici are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction and obtain the Chinese medicine preparation for the treatment of epilepsy.
Embodiment 2:
Take Stichopus japonicus 10g, Folium Isatidis 5g, Herba Bryophylli Pinnati 30g, Herba Artemisiae Anomalae 5g, Semen Iridis 30g, Flos lupuli (Flos Humuli Lupuli) 5g, Radix Isatidis 30g, Fructus Rubi 5g, Folium Rhododendri Daurici 30g; Above-mentioned Folium Isatidis, Herba Bryophylli Pinnati, Herba Artemisiae Anomalae, Semen Iridis, Flos lupuli (Flos Humuli Lupuli), Radix Isatidis, Fructus Rubi, Folium Rhododendri Daurici are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction and obtain the Chinese medicine preparation for the treatment of epilepsy.
Embodiment 3:
Take Stichopus japonicus 8g, Folium Isatidis 18g, Herba Bryophylli Pinnati 18g, Herba Artemisiae Anomalae 17g, Semen Iridis 17g, Flos lupuli (Flos Humuli Lupuli) 17g, Radix Isatidis 18g, Fructus Rubi 17g, Folium Rhododendri Daurici 17g; Above-mentioned Folium Isatidis, Herba Bryophylli Pinnati, Herba Artemisiae Anomalae, Semen Iridis, Flos lupuli (Flos Humuli Lupuli), Radix Isatidis, Fructus Rubi, Folium Rhododendri Daurici are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction and obtain the Chinese medicine preparation for the treatment of epilepsy.
Clinical data:
To Anhui 300, routine epileptic carries out clinical observation treatment, wherein male's 157 examples, and women's 143 examples, the age 17 is to 62 years old, 45 years old mean age.Be divided into immediately 3 treatment groups, every group of 100 people, treatment group 1 adopts the lotion for treatment of embodiment 1; Treatment group 2 adopts the lotion for treatment of embodiment 2; Treatment group 3 adopts the lotion for treatment of embodiment 3.
(1) Therapeutic Method:
Every day, potion, took at twice; Take continuously treatment 30 days.
(2) efficacy assessment standard: with reference to reference to the ordered antiepileptic (Western medicine) of 1979 Qingdao meetings evaluation of clinical curative effect standard on probation, divide level Four evaluation.
Effective: after medication, epilepsy control, or attack times reduces more than 75% before treatment in same period, and when outbreak, symptom and persistent period all obviously alleviate and shorten, electroencephalogram improvement.
Effective: after medication, epilepsy number of times reduces 50%～75% before treatment in same period, there be alleviating and shortening in various degree outbreak symptom and the persistent period, and electroencephalogram is slightly improved.
Heterodyne: after medication, epilepsy number of times reduces less than 50% before treatment in same period, and outbreak symptom and time are not improved, and electroencephalogram is unchanged.
Invalid: after medication, number of times, the clinical symptoms etc. of epilepsy is all unchanged, even trend is serious.
(3) therapeutic effect:
Treatment group 1: effective 67 examples, account for 67%; Effective 32 examples, account for 32%; Heterodyne 1 example, accounts for 1%; Invalid 0 example; Total effective rate 99%;
Treatment group 2: effective 96 examples, account for 96%; Effective 4 examples, account for 4%; Heterodyne 0 example; Invalid 0 example; Total effective rate 100%;
Treatment group 3: effective 68 examples, account for 68%; Effective 29 examples, account for 29%; Heterodyne 3 examples, account for 3%; Invalid 0 example; Total effective rate 97%.
The above, be only preferred embodiment of the present invention, is not intended to limit protection scope of the present invention.One skilled in the art will appreciate that protection scope of the present invention is as the criterion with appending claims.
Claims (1)
1. contain a Chinese medicine preparation for the treatment epilepsy of Stichopus japonicus composition, it is characterized in that preparation method is: take Stichopus japonicus 5 ~ 10 weight portions, Folium Isatidis 5 ~ 30 weight portions, Herba Bryophylli Pinnati 5 ~ 30 weight portions, Herba Artemisiae Anomalae 5 ~ 30 weight portions, Semen Iridis 5 ~ 30 weight portions, Flos lupuli (Flos Humuli Lupuli) 5 ~ 30 weight portions, Radix Isatidis 5 ~ 30 weight portions, Fructus Rubi 5 ~ 30 weight portions, Folium Rhododendri Daurici 5 ~ 30 weight portions; Above-mentioned Folium Isatidis, Herba Bryophylli Pinnati, Herba Artemisiae Anomalae, Semen Iridis, Flos lupuli (Flos Humuli Lupuli), Radix Isatidis, Fructus Rubi, Folium Rhododendri Daurici are put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water, to exceed powder 2-3cm as degree, soaks half an hour; After boiling with high heat, use again slow fire boiling half an hour instead; Stichopus japonicus is gilled and clean up after add and in drug-decocting appliance, continue slow fire boiling half an hour, remove medicinal residues, get decoction.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860834A (en) * | 2014-04-11 | 2014-06-18 | 郑家园 | Sea cucumber ingredient containing traditional Chinese medicine preparation for treating epilepsy |
| CN107753777A (en) * | 2017-09-28 | 2018-03-06 | 陆垚西 | A kind of Yao nationality medicine endo-medicine for treating epilepsy and preparation method thereof |
-
2014
- 2014-04-11 CN CN201410144663.0A patent/CN103948750A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103860834A (en) * | 2014-04-11 | 2014-06-18 | 郑家园 | Sea cucumber ingredient containing traditional Chinese medicine preparation for treating epilepsy |
| CN103860834B (en) * | 2014-04-11 | 2016-05-11 | 朱长怀 | A kind of Chinese medicine preparation for the treatment of epilepsy |
| CN107753777A (en) * | 2017-09-28 | 2018-03-06 | 陆垚西 | A kind of Yao nationality medicine endo-medicine for treating epilepsy and preparation method thereof |
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Application publication date: 20140730 |