CN104740561A - Phlegm-eliminating and stasis-removing medicine for removing breast tumor and preparation method of phlegm-eliminating and stasis-removing medicine - Google Patents

Abstract

The invention discloses a phlegm-eliminating and stasis-removing medicine for removing a breast tumor. The phlegm-eliminating and stasis-removing medicine is prepared from the following main raw materials in parts by weight: 9-15 parts of kelp, 8-15 parts of rhizoma sparganii, 6-9 parts of poria cocos, 5-10 parts of stellaria yunnanensis, 9-16 parts of chickweed, 2-6 parts of silkworm larva, 8-16 parts of brucea javanica, 8-16 parts of eleusine indica, 5-10 parts of sweet clover, 10-15 parts of fructus aurantii, 8-12 parts of curcuma zedoary, 10-15 parts of curcuma aromatic, 10-20 parts of bamboo shavings, 10-20 parts of roasted ginger, 8-15 parts of cuttle bone and 9-12 parts of raw oyster shell. The phlegm-eliminating and stasis-removing medicine has the efficacies of activating blood, removing stasis, eliminating phlegm, removing stasis, inducing resuscitation, activating collaterals, reducing swelling and relieving pain, and has an obvious curative effect on the breast tumor.

Description

Eliminate expectorant powder junction medicine and the preparation method of breast tumor

Technical field

The present invention relates to traditional Chinese medicine field, particularly relate to a kind of expectorant powder junction medicine and the preparation method of eliminating breast tumor.

Background technology

Early stage breast tumor mostly occurs at the first half of breast, accounts for more than 50%, wherein again with outside upper quadrant morbidity at most, more relevant with breast outside upper gland leaf.Early stage breast tumor originates from glandular tube epithelium, and cancer in situ is difficult to find.Also have a kind of rare breast carcinoma to be invisible breast carcinoma, in its breast, lump can not find, but has occurred that oxter is shifted.The many no conscious symptons of breast tumor, lump be often patient inadvertently (as having a bath, changing one's clothes) find.

The Symptoms of early stage breast tumor: 1. lump: patient is to find in breast that lump clients accounts for the overwhelming majority, and lump morphological differences is comparatively large, and it is generally acknowledged that form is irregular, blur margin is clear, and quality is partially hard.Carcinous lump is limited in mammary gland essence in early days, still can promote, but does not have larger mobility like that like benign tumor, once invade fascia or skin, lump just can not promote, and stadium also belongs to more late.2. mammary gland pain: though be found in multiple mastopathy, pain is not the common sympton of breast tumor, no matter optimum or malignant breast tumor is normally painless.In early days in breast carcinoma, occasionally having with pain is unique symptom, can be dull pain or sense of dragging, when lying on one's side more so.Have research display, there is mammary gland pain and increase thick one with body of gland in postmenopausal women, breast cancer detection rate will increase.Certainly, tumor can have distending pain or tenderness with during inflammation.If late tumor is invaded and neural or axillary lymph nodes enlargement compressing or can have shoulder distending pain when invading brachial plexus nerve.3. nipple discharge: have physiological and pathologic point, physiological nipple discharge are mainly seen in gestation and breast-feeding female, and pathologic nipple discharge refer to the breast duct bleeding under non-physiological state, usually said finger the latter.Recent research shows, nipple discharge are the more early stage clinical manifestations of some breast carcinoma, particularly intraductal carcinoma, and get final product individualism before not forming obvious lump.4. nipple changes: be usually expressed as nipple erosion or nipple retraction.Nipple is rotten to the corn: the typical performance having a kind of Paget's disease of breast, often accompanies pruritus, and about 2/3 patient can with the lump at mammary areola or other positions of breast.Nipple bounces back: when tumors invading and nipple or subareolar area, and the fibrous tissue of mammary gland and conduit system shorten, and tractive nipple, makes it cave in, deflection, even completely retraction mammary areola rear.5. skin change: breast tumor causes the change of skin, relevant with infringement degree with the position of tumor, the depth, usually following several performance is had: 1. skin adhesion: mammary gland is between the depth two fascia, and the shallow-layer of superficial fascia is connected with skin, and deep layer invests pectoralis major superficial surface.Superficial fascia forms interlobular septum in mammary gland tissue, i.e. suspensory ligaments of breast.When tumors invading and these ligaments, can make it to shrink, shorten, tractive skin forms depression, and shape as dimple, therefore claims " dimple sign ".2. skin superficial varicosis: gross tumor volume is comparatively large or when growing very fast, its surface skin can be made to become poor, and its lower superficial vein, vein often can varicose.3. skin rubefaction: during acute and chronic mastitis, skin of mammary gland can have redness.4. hydroderma: due to mammary subcutaneous lymphatic vessel to be blocked by tumor cell or mammary gland central area by tumor cell invasion, make lymphatics of mammary gland backflow obstruction, intravascular lymph liquid gathers, and skin is thickening, and follicular orifice expands, get deeply stuck in and show orange peel and change.

At present, the medicine for the treatment of breast tumor exists, and for the problems referred to above, publication number CN 101732547 A (application number 200910226773.0) patent document discloses a kind of nodule removing and breast caring capsule, its raw material composition and consumption weight are: Radix Notoginseng 0.05-5 gram, Radix Panacis Quinquefolii 0.05-5 gram, Ganoderma 0.05-5 gram, Radix Salviae Miltiorrhizae 0.05-5 gram, Radix Puerariae 0.05-5 gram, Poria 0.05-5 gram, Radix Asparagi 0.1-5 gram, Carapax et Plastrum Testudinis 0.05-5 gram.Publication number CN 102697973 A(application number 201210136406.3) patent document discloses a kind of newborn Kang An sachet, provide a kind of using several precious Chinese herbal medicine: the derivant of the form that chemically can accept of the combined extracts such as Herba Houttuyniae, flying apsaras sieve Wield, calabash any of several broadleaf plants, wild Ganoderma, Lignum Aquilariae Resinatum, Catalpa or extract is prepared into the medicine such as powder or granule as main component or pharmaceutically acceptable physical aspect makes newborn Kang An sachet.Publication number CN 104288489 A(application number 201410501826.6) patent document discloses a kind of medicine being used for the treatment of breast tumor and preparation method thereof, the raw material by following parts by weight: cracked feet brown shelf fungus 40-50 part, Codiumfragile(sur.) Hariot. 33-40 part, Phellinus igniarius (L. ex Fr.) Quel. 25-30 part, leopard eyes flower 15-20 part, Stigma Croci 10-12 part, Radix Ranunculi Ternati 10-12 part, Herba Schizonepetae 10-12 part, Radix Ophiopogonis 10-12 part.

Current doctor trained in Western medicine take excision as first-selection, and combination with radiotherapeutic, chemotherapy, endocrine therapy and immunotherapy etc., and operative treatment is not only comparatively large to body injury, and can only for observable cancer cell, helpless to invisible cancerous cell.Chemicotherapy can heavy damage normal immune system, and make the body immunity of patient, lower for the resistance, along with the decline of immunity, resistance, the transfer diffusion velocity of cancerous cell can be faster, and have larger toxic and side effects after radiotherapy in the treatment.

Summary of the invention

For the deficiencies in the prior art, an object of the present invention is to provide a kind of expectorant powder junction medicine eliminating breast tumor, has blood circulation promoting and blood stasis dispelling, expectorant powder junction, dredging collateral of having one's ideas straightened out, effect of reducing swelling and alleviating pain, has obvious curative effect to breast tumor.Another object of the present invention is just to provide the preparation method of above-mentioned expectorant powder junction medicine.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

Eliminate the expectorant powder junction medicine of breast tumor, take off the primary raw material stating weight proportion and be prepared from: Thallus Laminariae (Thallus Eckloniae) 9-15 part; Rhizoma Sparganii 8-15 part; Poria 6-9 part; Radix Stellariae Yunnanensis 5-10 part; Herba stellariae mediae 9-16 part; Bombyx Batryticatus 2-6 part; Fructus Bruceae 8-16 part; Herba Eleusines Indicae 8-16 part; Melilotus 5-10 part; Fructus Aurantii 10-15 part; Rhizoma Curcumae 8-12 part; Radix Curcumae 10-15 part; Caulis Bambusae In Taenia 10-20 part; Rhizoma Zingiberis Preparatum 10-20 part; Os Sepiae 8-15 part; Concha Ostreae 9-12 part.

Eliminate the expectorant powder junction medicine of breast tumor, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Thallus Laminariae (Thallus Eckloniae) 11-13 part; Rhizoma Sparganii 10-13 part; Poria 7-8 part; Radix Stellariae Yunnanensis 6-9 part; Herba stellariae mediae 11-14 part; Bombyx Batryticatus 3-5 part; Fructus Bruceae 11-13 part; Herba Eleusines Indicae 11-13 part; Melilotus 6-9 part; Fructus Aurantii 11-14 part; Rhizoma Curcumae 9-11 part; Radix Curcumae 11-14 part; Caulis Bambusae In Taenia 13-17 part; Rhizoma Zingiberis Preparatum 13-17 part; Os Sepiae 10-13 part; Concha Ostreae 10-11 part.

Eliminate the expectorant powder junction medicine of breast tumor, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from :thallus Laminariae (Thallus Eckloniae) 12 parts; Rhizoma Sparganii 12 parts; 7.5 parts, Poria; Radix Stellariae Yunnanensis 7 parts; Herba stellariae mediae 12 parts; Bombyx Batryticatus 4 parts; Fructus Bruceae 12 parts; Herba Eleusines Indicae 12 parts; Melilotus 7 parts; Fructus Aurantii 12 parts; Rhizoma Curcumae 10 parts; Radix Curcumae 12 parts; Caulis Bambusae In Taenia 15 parts; Rhizoma Zingiberis Preparatum 15 parts; Os Sepiae 12 parts; Concha Ostreae 10.5 parts.

Present invention also offers the preparation method expectorant powder junction medicine of above-mentioned elimination breast tumor being made pharmaceutically acceptable powder, decoction, capsule, pill and tablet.

The preparation method of the expectorant powder junction powdered medicine of described elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), dry in the air cool, be ground into fine powder altogether, excessively 140-180 mesh sieve (preferred 150-170 mesh sieve excessively, was more preferably 160 mesh sieves);

(3) Tumble Dry Thallus Laminariae (Thallus Eckloniae), Rhizoma Sparganii, Radix Stellariae Yunnanensis, Herba stellariae mediae, Herba Eleusines Indicae, melilotus, Fructus Aurantii, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum (preferable temperature 80-90 DEG C, be more preferably temperature 85 DEG C), be placed in pulverizer to pulverize, cross 140-180 mesh sieve (preferred 150-170 mesh sieve excessively, was more preferably 160 mesh sieves);

(4) by step (1)-(3) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.

Instructions of taking: at every turn get 8-10g, is placed in tea bag, soaks, every day 2-3 time, 10 days courses for the treatment of by the warm waters of about 50 DEG C.

The preparation method of the expectorant powder junction medicine decoction of described elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, filter, be concentrated into 1/2 of original volume, sterile packaged, obtain decoction.

Instructions of taking: each 15-20ml, with the warm water delivery service of about 35 DEG C, every day 2-3 time, 10 days courses for the treatment of.

The preparation method of the expectorant powder junction Drug Capsule of described elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) join in step (3) gained filtrate by step (1) gains, mixing, is condensed into the thick paste that relative density is 1.10-1.20, be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, is more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;

(5) step (4) gained medicated powder is made capsule (preferably by the specification of 0.5g/ grain) by the specification of 0.4g-0.6g/ grain.

The preparation method of the expectorant powder junction Drug Capsule of above-mentioned elimination breast tumor, step (4) is preferably condensed into the thick paste that relative density is 1.13-1.17, is more preferably and is condensed into the thick paste that relative density is 1.15.

Instructions of taking: at every turn get 2-3 grain, every day 3 times, 10 days courses for the treatment of.

The preparation method of the expectorant powder junction pill agent of described elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, be condensed into the thick paste that relative density is 1.10-1.30 and (be preferably condensed into the thick paste that relative density is 1.15-1.25, be more preferably and be condensed into the thick paste that relative density is 1.20), be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;

(5) Mel is placed in pot, slow fire is tempered to thick, adds step (4) gained medicated powder, fully mixes into ointment thoroughly, pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm) is made by traditional Chinese medical science tradition pill method.

The preparation method of the expectorant powder junction pill agent of above-mentioned elimination breast tumor, the consumption of the preferred Mel of step (5) is the 30%-40% of medicated powder quality, and the consumption being more preferably Mel is 35% of medicated powder quality.

Instructions of taking: each 10-15 ball, every day 3 times, 10 days courses for the treatment of.

The preparation method of the expectorant powder junction tablet of described elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, be condensed into the thick paste that relative density is 1.10-1.30 and (be preferably condensed into the thick paste that relative density is 1.15-1.25, be more preferably and be condensed into the thick paste that relative density is 1.20), with fashion of extrusion by 18-26 eye mesh screen (preferred 20-24 eye mesh screen excessively, was more preferably 22 eye mesh screens), make single-size, drying, is pressed into lamellar, sugar coating.

Instructions of taking: each 2-3 sheet, every day 3 times, 10 days courses for the treatment of.

Technical advantage of the present invention is mainly reflected in:

1, the present invention eliminate the expectorant powder junction medicine of breast tumor each raw material effect work in coordination with, all medicine compatibilities, bring out the best in each other, and make the treatment of breast tumor reach treating both the principal and secondary aspects of a disease.

2, expectorant powder junction medical instrument of the present invention has blood circulation promoting and blood stasis dispelling, expectorant powder junction, dredging collateral of having one's ideas straightened out, effect of reducing swelling and alleviating pain, can suppress rapidly, kill and wound, killing off tumor cells, thus it is different softening and reduce that cancerous protuberance was had in the short time (in 3-7 days).

3, expectorant powder junction medicine of the present invention is evident in efficacy, take 3-5 the course for the treatment of stable disease, control cancerous protuberance diffusion, transfer, progressively disappear, part lump and cancerous protuberance can disappear completely.

4, the expectorant powder junction medicine selected materials great majority of this elimination breast tumor are Chinese medicine material, and medical material is easy to get, and cost is low.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.

embodiment 1eliminate the expectorant powder junction medicine of breast tumor, take off the primary raw material stating weight proportion and be prepared from (getting 40g for every part): Thallus Laminariae (Thallus Eckloniae) 9 parts; Rhizoma Sparganii 8 parts; 6 parts, Poria; Radix Stellariae Yunnanensis 5 parts; Herba stellariae mediae 9 parts; Bombyx Batryticatus 2 parts; Fructus Bruceae 8 parts; Herba Eleusines Indicae 8 parts; Melilotus 5 parts; Fructus Aurantii 10 parts; Rhizoma Curcumae 8 parts; Radix Curcumae 10 parts; Caulis Bambusae In Taenia 10 parts; Rhizoma Zingiberis Preparatum 10 parts; Os Sepiae 8 parts; Concha Ostreae 9 parts.

The preparation method of the expectorant powder junction powdered medicine of above-mentioned elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder sunk as above method repeatable operation 2 times, discards impurity, merges suspension, leaves standstill 3 hours, the clear water inclined above, gets precipitation and dries, porphyrize, crosses 140 mesh sieves;

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat fries 25 minutes, dries in the air cool, is ground into fine powder altogether, crosses 160 mesh sieves;

(3) Tumble Dry Thallus Laminariae (Thallus Eckloniae), Rhizoma Sparganii, Radix Stellariae Yunnanensis, Herba stellariae mediae, Herba Eleusines Indicae, melilotus, Fructus Aurantii, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum (temperature 85 DEG C), is placed in pulverizer and pulverizes, and crosses 160 mesh sieves;

(4) by step (1)-(3) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.

Instructions of taking: at every turn get 10g, is placed in tea bag, soaks, every day 3 times, 10 days courses for the treatment of by the warm waters of about 50 DEG C.

embodiment 2eliminate the expectorant powder junction medicine of breast tumor, take off the primary raw material stating weight proportion and be prepared from (every part of 18g): Thallus Laminariae (Thallus Eckloniae) 15 parts; Rhizoma Sparganii 15 parts; 9 parts, Poria; Radix Stellariae Yunnanensis 10 parts; Herba stellariae mediae 16 parts; Bombyx Batryticatus 6 parts; Fructus Bruceae 16 parts; Herba Eleusines Indicae 16 parts; Melilotus 10 parts; Fructus Aurantii 15 parts; Rhizoma Curcumae 12 parts; Radix Curcumae 15 parts; Caulis Bambusae In Taenia 20 parts; Rhizoma Zingiberis Preparatum 20 parts; Os Sepiae 5 parts; Concha Ostreae 12 parts.

The preparation method of the expectorant powder junction medicine decoction of above-mentioned elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder sunk as above method repeatable operation 2 times, discards impurity, merges suspension, leaves standstill 3 hours, the clear water inclined above, gets precipitation and dries, porphyrize, crosses 140 mesh sieves;

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat fries 25 minutes, sprays rice vinegar, floods intense fire fried dry after 4 minutes, and taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 40 minutes, add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, filter, be concentrated into 1/2 of original volume, sterile packaged, obtain decoction.

Instructions of taking: each 20ml, every day 3 times, 10 days courses for the treatment of.

model case onexue XX, female, 37 years old, people from Guanyao County, Handan in Hebei province.The year before because having light yellow liquid body pollution in the left side medicated bra that stumbles on, when going to see a doctor, doctor says it is a kind of disease being called breast intraductal papilloma, allows its hospitalisation for surgery.She thinks, does not ache again and does not itch, also touch less than lump, need not perform an operation.So, just have rejected operation and gone home.After 1 year, feel that nipple, mammary areola district distending pain, nipple discharge become courageous and upright material, just feel the seriousness that goes wrong, now the state of an illness has developed more serious, find on inspection at it in the large conduit at disk center position, have the little tumor of the band base of a fruit of a 0.6cm × 0.4cm, left breast is outside upper resembles protuberance, and skin has slightly " Pericarpium Citri Reticulatae sample ".After giving corresponding Breastconserving therapy, fail to fully recover.

Take after gained of the present invention eliminates 2 courses for the treatment of of expectorant powder junction medicine decoction (embodiment 2) of breast tumor, lump obviously reduces, and the outside upper quadrant of left breast can touch the lump of 0.3*0.2*0.2cm.So continue to take 2 courses for the treatment of, the basic cancellation of lump, nipple galactorrhea phenomenon also disappears, and tracing observation is fully recovered, and symptom is without recurrence.

embodiment 3eliminate the expectorant powder junction medicine of breast tumor, take off the primary raw material stating weight proportion and be prepared from (getting 30g for every part): Thallus Laminariae (Thallus Eckloniae) 11 parts; Rhizoma Sparganii 10 parts; 7 parts, Poria; Radix Stellariae Yunnanensis 6 parts; Herba stellariae mediae 11 parts; Bombyx Batryticatus 3 parts; Fructus Bruceae 11 parts; Herba Eleusines Indicae 11 parts; Melilotus 6 parts; Fructus Aurantii 11 parts; Rhizoma Curcumae 9 parts; Radix Curcumae 11 parts; Caulis Bambusae In Taenia 13 parts; Rhizoma Zingiberis Preparatum 13 parts; Os Sepiae 10 parts; Concha Ostreae 10 parts.

The preparation method of the expectorant powder junction Drug Capsule of above-mentioned elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder sunk as above method repeatable operation 2 times, discards impurity, merges suspension, leaves standstill 3 hours, the clear water inclined above, gets precipitation and dries, porphyrize, crosses 140 mesh sieves;

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat fries 25 minutes, sprays rice vinegar, floods intense fire fried dry after 4 minutes, and taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 40 minutes, add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) join in step (3) gained filtrate by step (1) gains, mixing, is condensed into the thick paste that relative density is 1.15, is modulated into the soft material that light pressure is then loose, crosses 100 mesh sieves, dry, pulverize, obtain medicated powder;

(5) step (4) gained medicated powder is made capsule by the specification of 0.5g/ grain.

Instructions of taking: each 2-3 grain, every day 3 times, 10 days courses for the treatment of.

embodiment 4eliminate the expectorant powder junction medicine of breast tumor, take off the primary raw material stating weight proportion and be prepared from (getting 25g for every part): Thallus Laminariae (Thallus Eckloniae) 13 parts; Rhizoma Sparganii 13 parts; 8 parts, Poria; Radix Stellariae Yunnanensis 9 parts; Herba stellariae mediae 14 parts; Bombyx Batryticatus 5 parts; Fructus Bruceae 13 parts; Herba Eleusines Indicae 13 parts; Melilotus 9 parts; Fructus Aurantii 14 parts; Rhizoma Curcumae 11 parts; Radix Curcumae 14 parts; Caulis Bambusae In Taenia 17 parts; Rhizoma Zingiberis Preparatum 17 parts; Os Sepiae 13 parts; Concha Ostreae 11 parts.

The preparation method of the expectorant powder junction pill agent of above-mentioned elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder sunk as above method repeatable operation 2 times, discards impurity, merges suspension, leaves standstill 3 hours, the clear water inclined above, gets precipitation and dries, porphyrize, crosses 140 mesh sieves;

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat fries 25 minutes, sprays rice vinegar, floods intense fire fried dry after 4 minutes, and taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 40 minutes, add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) join in step (3) gained filtrate by step (1) gains, mixing, is condensed into the thick paste that relative density is 1.20, is modulated into the soft material that light pressure is then loose, crosses 100 mesh sieves, dry, pulverize, obtain medicated powder;

(5) be placed in pot by Mel, slow fire is tempered to thick, adds step (4) gained medicated powder, fully mixes into ointment thoroughly, makes by the traditional Chinese medical science tradition pill method pill that diameter is 4mm.

Instructions of taking: each 10 balls, every day 3 times, 10 days courses for the treatment of.

model case twothank to XX, female, 39 years old, people from Tongzhou, Nantong City.Left swelling of the breast thing more than 10 years, is about 0.4cm*0.4cm*0.3cm during discovery, so far about 4cm*3cm*3cm size, and outside upper quadrant has slightly " Pericarpium Citri Reticulatae sample " to change, and increasess slowly, painless.Left laitance skin and nipple are normal, and swollen thing is positioned at the outside upper and LOQ of left breast, and matter is hard, without tenderness, without adhesion fusion, activity still can, border owes clear.Ultrasonic examination: left breast is outside upper and LOQ is visited and a swollen thing, and tentative diagnosis is breast tumor, once intermittently takes multiple antibiotic medicine, all without positive effect.

Take after gained of the present invention eliminates 2 courses for the treatment of of expectorant powder junction pill agent (embodiment 4) of breast tumor, symptom obviously alleviates, and lump obviously reduces.After continuing to take 2 courses for the treatment of, go examination in hospital to find tumor cancellation substantially, do not continue development.Later stage follows up a case by regular visits to and learns and fully recover.

embodiment 5eliminate the expectorant powder junction medicine of breast tumor, take off the primary raw material stating weight proportion and be prepared from (getting 10g for every part): Thallus Laminariae (Thallus Eckloniae) 12 parts; Rhizoma Sparganii 12 parts; 7.5 parts, Poria; Radix Stellariae Yunnanensis 7 parts; Herba stellariae mediae 12 parts; Bombyx Batryticatus 4 parts; Fructus Bruceae 12 parts; Herba Eleusines Indicae 12 parts; Melilotus 7 parts; Fructus Aurantii 12 parts; Rhizoma Curcumae 10 parts; Radix Curcumae 12 parts; Caulis Bambusae In Taenia 15 parts; Rhizoma Zingiberis Preparatum 15 parts; Os Sepiae 12 parts; Concha Ostreae 10.5 parts.

The preparation method of the expectorant powder junction tablet of above-mentioned elimination breast tumor, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder sunk as above method repeatable operation 2 times, discards impurity, merges suspension, leaves standstill 3 hours, the clear water inclined above, gets precipitation and dries, porphyrize, crosses 140 mesh sieves;

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat fries 25 minutes, sprays rice vinegar, floods intense fire fried dry after 4 minutes, and taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 40 minutes, add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 35 minutes at every turn, twice filtrate merges;

(4) join in step (3) gained filtrate by step (1) gains, mixing, is condensed into the thick paste that relative density is 1.20, with fashion of extrusion by 22 eye mesh screens, makes single-size, dry, is pressed into lamellar, sugar coating.

Instructions of taking: each 2-3 sheet, every day 3 times, 10 days courses for the treatment of.

The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:

Thallus Laminariae (Thallus Eckloniae): salty in the mouth, cold in nature.Return liver, stomach, kidney channel.For the dry thallus of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) or Alariaceae plant Thallus Laminariae (Thallus Eckloniae).There is hard masses softening and resolving, expectorant, effect of diuretic.For wart cancer, scrofula, painful and swollen testis, phlegm retention edema.

Rhizoma Sparganii: acrid in the mouth, hardship, property is put down.Return liver, spleen channel.For the dry tuber of Sparganiaceae plant rhizoma scirpi.There is removing blood stasis circulation of qi promoting, effect of removing food stagnancy pain relieving.Yong Yu Disorder trace mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain.

Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.For the dry sclerotia of On Polyporaceae Poria.Have promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieve internal heat anticancer effect.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia, dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, and malignant histocytosis, has loose bowels, seminal emission, stranguria with turbid discharge, and palpitation with fear is forgetful.

Radix Stellariae Yunnanensis: sweet in the mouth, property is put down.For the root of pinkwort Yunnan Herba stellariae mediae.There is strong board, nourishing the liver, effect of kidney tonifying.For the empty anemia of body, spirit is deficient, dizzy nervous, tinnitus dim eyesight, hectic fever, seminal emission, lumbago flaccidity of the lower limbs, and menoxenia, leukorrhagia drenches drop, infantile malnutrition.

Herba stellariae mediae: sweet in the mouth, acid, cool in nature.For Caryophyllaceae Stellaria plant Herba stellariae mediae, with all herbal medicine.Herb is containing Saponin 4.5%, and main ruscogenin is gypsogenin, again containing flavones ingredient: orientin, isorientin, vitexin, isovitexin, luteolin etc.There is heat-clearing and toxic substances removing, blood-activating analgetic, effect of lactogenic.For enteritis, dysentery, hepatitis, appendicitis, postnatal blood stasis is suffered from abdominal pain, uterine contraction pain, toothache, early whitening of hair, agalactia, mastitis, traumatic injury, sore swollen toxin.

Bombyx Batryticatus: acrid in the mouth, salty, property is put down.Return liver, lung, stomach warp.For the larva of Bombycidae insecticide bombyx mori infects muscardine and ossified dry Scorpio.Containing protein, ammonium oxalate, and containing lysine, leucine, aspartic acid etc. 17 seed amino acid, 28 kinds of elements such as magnesium, calcium, zinc, and abnormal activity melts hormone, ecdysone and a kind of pigment 3-hydroxyl cynruin, 6-N-ethoxy adenine.There is expelling wind to relieve convulsion, effect of dissipating phlegm and resolving masses.For apoplectic aphasia, middle tuyere nose eye is oblique, and infantile convulsion is twitched, wind syndrome of head, acute throat trouble, laryngopharynx swelling and pain, scrofula, mumps, rubella, sore sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis.

Fructus Bruceae: bitter in the mouth, cold in nature.Return large intestine, Liver Channel.For the dry mature fruit of quassia Fructus Bruceae.There is heat-clearing and toxic substances removing, preventing the attack (or recurrence) of malaria, dysentery relieving, effect of corrosion wart.For dysentery, malaria; External treatment wart, clavus.

Herba Eleusines Indicae: sweet in the mouth, light, property is put down.Return liver, stomach two warp.For the herb of grass family yard grass platymiscium Herba Eleusines Indicae.Containing isorientin, luteolin-7-O-rutinoside, tricin, luteolin-7-O-glycoside, special Jing Su, isovitexin.There is heat-clearing and toxic substances removing, expelling wind and removing dampness, effect of dissipating blood stasis hemostasis.For preventing and treating epidemic encephalitis type B, epidemic cerebrospinal meningitis, rheumatic arthritis, icterohepatitis, infantile dyspepsia, enteritis, dysentery, urethritis; Traumatic injury is controlled in external, traumatic hemorrhage, dog bite.

Melilotus: bitter in the mouth, light, cool in nature.Belong to pulse family, biennial herb, high 40-100 centimetre, is born in hillside, riverbank, roadside, chiltern meadow.There is effect of heat-clearing and toxic substances removing, be used for the treatment of skin scar, red wind, dysentery with red and white feces, gonorrhea.

Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.For the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.There is regulating the flow of QI to ease the stomach, effect of the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, uterine prolapse.

Rhizoma Curcumae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.For the dry rhizome of zingiberaceous plant Rhizoma Curcumae, Guangxi zedoary or RADIX CURCUMAE.There is circulation of qi promoting removing blood stasis, effect of removing food stagnancy pain relieving.Yong Yu mass in the abdomen mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain, early cervical carcinoma.

Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.For the dried root of zingiberaceous plant RADIX CURCUMAE, Rhizoma Curcumae Longae, Guangxi zedoary or Rhizoma Curcumae.There is regulating qi to disperse stagnation, heart fire-clearing upset-relieving, effect of promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.

Caulis Bambusae In Taenia: sweet in the mouth, cold in nature.Attach to the lung and stomach meridians.For the dry intermediate layer of the stem stalk of grass bambusa breviflora Munro, major part allusion quotation bamboo or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.There is removing heat-phlegm, the effect relieved restlessness and prevented vomiting.For phlegm-heat cough, expectorant held under the arm by gallbladder fire, and dysphoria with smothery sensation is vomitted, palpitation with fear insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.

Rhizoma Zingiberis Preparatum: acrid in the mouth, hot in nature.Return board, stomach, kidney, the heart, lung meridian.For the Preparation process product of Rhizoma Zingiberis.There is warming spleen and stomach for dispelling cold, effect of warming the meridian for stopping bleeding.For Deficiency and coldness of spleen and stomach, stomachache is vomited and diarrhoea, and tell rule metrorrhagia, yang deficiency is lost blood.

Os Sepiae: salty in the mouth, puckery, warm in nature.Return spleen, kidney channel.For the dry inner shell of Sepiidae animal sepiella maindroni de Rochebrune or golden cuttlefish.Containing calcium carbonate more than 85%, in addition, containing methionine, aspartic acid, glutamic acid etc.There is astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, effect of sore.For Peptic Ulcers, hyperchlorhydria, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge, stomachache acid regurgitation; External treatment bleeding due to trauma, the many pus of skin ulcer.

Concha Ostreae: salty in the mouth, cold nature.Return liver, gallbladder, kidney channel.For the shell of the long Concha Ostreae of Ostreidae animal, Dalian Bay Concha Ostreae or Crassostrea rivularis.There is tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, restrain astringent or styptic treatment for spontaneous sweating effect.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.

test examplein order to verify that gained of the present invention eliminates the curative effect of the expectorant powder junction medicine (embodiment 5) of breast tumor, do contrast test in July ,-2011 in June, 2009:

General data: screen 200 routine Breast Tumor Patients in Duo Jia hospital, wherein minimal ages 26 years old, max age 63 years old, 47.6 years old mean age; 26-30 year 49 people, 31-50 year 94 people, 51-63 year 57 people.Be divided into experimental group and matched group two groups (wherein experimental group 150 people, matched group 50 people) at random, two groups are compared there was no significant difference (P > 0.05), have comparability in sex, age, the course of disease, state of an illness scoring etc.

Diagnostic criteria: nipple discharge; Nipple and mammary areola change; Local skin changes; Breast contours changes; Axillary fossa and supraclavicular fossa lymph node etc.

Usage and dosage: experimental group takes the expectorant powder junction tablet that gained of the present invention eliminates breast tumor, each 2, every day 3 times, 10 days courses for the treatment of; Matched group takes other medicine (as PINGXIAO JIA0NANG, Traditional Chinese medicinal liquid for eliminating module in breast etc.), wherein, and PINGXIAO JIA0NANG: oral, a 4-8 grain, 3 times on the one; Traditional Chinese medicinal liquid for eliminating module in breast: oral, a 10ml, 2 times on the one, shakes up when taking.

Criterion of therapeutical effect: cure: after 4 courses for the treatment of of medication, lump in breast disappears, and malaise symptoms disappears.Effective: after 4 courses for the treatment of of medication, lump in breast obviously reduces, and malaise symptoms is obviously alleviated.Invalid: after 4 courses for the treatment of of medication, symptom is unchanged.

4 courses for the treatment of of medication treatment, observe latter 1 year for the treatment of.Adopt the matched group of other drug and take the Comparison of therapeutic that gained of the present invention eliminates the experimental group of the expectorant powder junction medicine of breast tumor, result is as shown in table 1:

Table 1

As can be seen from Table 1, take gained of the present invention and eliminate the cure rate of the expectorant powder junction medicine of breast tumor up to 76.67%, effective percentage is up to 98%; And the cure rate taking other drug only 40%, effective percentage also only has 76%, and inefficiency is up to 24%.Can find out: the successful taking the expectorant powder junction medicine of gained of the present invention elimination breast tumor is better than taking the effect of other drug.

It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or obtain undoubtedly according to the written description of file, the claimed scope of this patent all should be thought.

Claims (10)

1. eliminate the expectorant powder junction medicine of breast tumor, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Thallus Laminariae (Thallus Eckloniae) 9-15 part; Rhizoma Sparganii 8-15 part; Poria 6-9 part; Radix Stellariae Yunnanensis 5-10 part; Herba stellariae mediae 9-16 part; Bombyx Batryticatus 2-6 part; Fructus Bruceae 8-16 part; Herba Eleusines Indicae 8-16 part; Melilotus 5-10 part; Fructus Aurantii 10-15 part; Rhizoma Curcumae 8-12 part; Radix Curcumae 10-15 part; Caulis Bambusae In Taenia 10-20 part; Rhizoma Zingiberis Preparatum 10-20 part; Os Sepiae 8-15 part; Concha Ostreae 9-12 part.

2. expectorant powder junction medicine according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Thallus Laminariae (Thallus Eckloniae) 11-13 part; Rhizoma Sparganii 10-13 part; Poria 7-8 part; Radix Stellariae Yunnanensis 6-9 part; Herba stellariae mediae 11-14 part; Bombyx Batryticatus 3-5 part; Fructus Bruceae 11-13 part; Herba Eleusines Indicae 11-13 part; Melilotus 6-9 part; Fructus Aurantii 11-14 part; Rhizoma Curcumae 9-11 part; Radix Curcumae 11-14 part; Caulis Bambusae In Taenia 13-17 part; Rhizoma Zingiberis Preparatum 13-17 part; Os Sepiae 10-13 part; Concha Ostreae 10-11 part.

3. expectorant powder junction medicine according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Thallus Laminariae (Thallus Eckloniae) 12 parts; Rhizoma Sparganii 12 parts; 7.5 parts, Poria; Radix Stellariae Yunnanensis 7 parts; Herba stellariae mediae 12 parts; Bombyx Batryticatus 4 parts; Fructus Bruceae 12 parts; Herba Eleusines Indicae 12 parts; Melilotus 7 parts; Fructus Aurantii 12 parts; Rhizoma Curcumae 10 parts; Radix Curcumae 12 parts; Caulis Bambusae In Taenia 15 parts; Rhizoma Zingiberis Preparatum 15 parts; Os Sepiae 12 parts; Concha Ostreae 10.5 parts.

4., according to the arbitrary described expectorant powder junction medicine of claim 1-3, it is characterized in that, the preparation method of described powder, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), dry in the air cool, be ground into fine powder altogether, excessively 140-180 mesh sieve (preferred 150-170 mesh sieve excessively, was more preferably 160 mesh sieves);

(3) Tumble Dry Thallus Laminariae (Thallus Eckloniae), Rhizoma Sparganii, Radix Stellariae Yunnanensis, Herba stellariae mediae, Herba Eleusines Indicae, melilotus, Fructus Aurantii, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum (preferable temperature 80-90 DEG C, be more preferably temperature 85 DEG C), be placed in pulverizer to pulverize, cross 140-180 mesh sieve (preferred 150-170 mesh sieve excessively, was more preferably 160 mesh sieves);

(4) by step (1)-(3) gained fine powder mix homogeneously, sterile packaged is carried out by pharmaceutically accepted specification.

5., according to the arbitrary described expectorant powder junction medicine of claim 1-3, it is characterized in that, the preparation method of described decoction, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, filter, be concentrated into 1/2 of original volume, sterile packaged, obtain decoction.

6., according to the arbitrary described expectorant powder junction medicine of claim 1-3, it is characterized in that, the preparation method of described capsule, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) join in step (3) gained filtrate by step (1) gains, mixing, is condensed into the thick paste that relative density is 1.10-1.20, be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, is more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;

(5) step (4) gained medicated powder is made capsule (preferably by the specification of 0.5g/ grain) by the specification of 0.4g-0.6g/ grain.

7. expectorant powder junction Drug Capsule preparation method according to claim 6, is characterized in that: step (4) is preferably condensed into the thick paste that relative density is 1.13-1.17, is more preferably and is condensed into the thick paste that relative density is 1.15.

8., according to the arbitrary described expectorant powder junction medicine of claim 1-3, it is characterized in that, the preparation method of described pill, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, be condensed into the thick paste that relative density is 1.10-1.30 and (be preferably condensed into the thick paste that relative density is 1.15-1.25, be more preferably and be condensed into the thick paste that relative density is 1.20), be modulated into the soft material that light pressure is then loose, cross 80-120 mesh sieve (preferred 90-110 mesh sieve, be more preferably 100 mesh sieves), dry, pulverize, obtain medicated powder;

(5) Mel is placed in pot, slow fire is tempered to thick, adds step (4) gained medicated powder, fully mixes into ointment thoroughly, pill (preferably make the pill that diameter is 3mm-5mm, be more preferably and make the pill that diameter is 4mm) is made by traditional Chinese medical science tradition pill method.

9. the preparation method of expectorant powder junction pill according to claim 8 agent, is characterized in that: the consumption of the preferred Mel of step (5) is the 30%-40% of medicated powder quality, and the consumption being more preferably Mel is 35% of medicated powder quality.

10., according to the arbitrary described expectorant powder junction medicine of claim 1-3, it is characterized in that, the preparation method of described tablet, step is as follows:

(1) Os Sepiae and Concha Ostreae are smashed, be placed in mortar, add clear water and grind to form pasty state, add water stirring, inclines and get suspension, the coarse powder of sinking as above method repeatable operation 2-3 time, discard impurity, merge suspension, leave standstill 2-4 hour, the clear water inclined above, get precipitation to dry, porphyrize, excessively 120-160 mesh sieve (preferred 130-150 mesh sieve excessively, was more preferably 140 mesh sieves);

(2) Poria, Bombyx Batryticatus and Fructus Bruceae are placed in frying pan, moderate heat is fried 20-30 minute (preferred moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes), and spray rice vinegar, flood intense fire fried dry after 3-5 minute, taking-up is dried in the air cool;

(3) Rhizoma Sparganii, Radix Stellariae Yunnanensis, Rhizoma Curcumae, Radix Curcumae, Caulis Bambusae In Taenia and Rhizoma Zingiberis Preparatum are placed in marmite, soak half an hour, intense fire is boiled, turn slow fire boiling 30-50 minute (preferably turn slow fire boiling 35-45 minute, be more preferably and turn slow fire boiling 40 minutes), add step (2) gains, Thallus Laminariae (Thallus Eckloniae), Herba stellariae mediae, Herba Eleusines Indicae, melilotus and Fructus Aurantii, decoct twice, boil 30-40 minute (preferably boil 33-37 minute at every turn, be more preferably and boil 35 minutes at every turn), twice filtrate merges at every turn;

(4) step (1) gains are joined in step (3) gained filtrate, mixing, be condensed into the thick paste that relative density is 1.10-1.30 and (be preferably condensed into the thick paste that relative density is 1.15-1.25, be more preferably and be condensed into the thick paste that relative density is 1.20), with fashion of extrusion by 18-26 eye mesh screen (preferred 20-24 eye mesh screen excessively, was more preferably 22 eye mesh screens), make single-size, drying, is pressed into lamellar, sugar coating.