CN101204552A - Chinese traditional medicine composite for breast cancer and cervical carcinoma and preparation method thereof - Google Patents

Chinese traditional medicine composite for breast cancer and cervical carcinoma and preparation method thereof Download PDF

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Publication number
CN101204552A
CN101204552A CNA200710178348XA CN200710178348A CN101204552A CN 101204552 A CN101204552 A CN 101204552A CN A200710178348X A CNA200710178348X A CN A200710178348XA CN 200710178348 A CN200710178348 A CN 200710178348A CN 101204552 A CN101204552 A CN 101204552A
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parts
radix
rhizoma
radix paeoniae
weight
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CNA200710178348XA
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鄢良
张韬
张云峰
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BEIJING ZHONGKE YONGHE MEDICAL TECHNOLOGY Co Ltd
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BEIJING ZHONGKE YONGHE MEDICAL TECHNOLOGY Co Ltd
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Publication of CN101204552A publication Critical patent/CN101204552A/en
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Abstract

The invention discloses a traditional Chinese medicine compound and a preparation method for treating breast cancer and cervical cancer, which is mainly made by cyperi rhizoma, zedoary, angelica, sparganii rhizome, red paeony root, paeoniae radix alba, citri exocarpium immaturum, linderae radix, safflower, sappan wood, cinnamomi cortex tubiformis, fructus psoralea and astragali radix. The traditional Chinese medicine compound provided by the invention has the effect of blood enriching and promoting and menstruation promoting and broomsymptom breaking, which mainly treats the diseases of menstrual atresia, abdominal masses ache, the breast cancer, the cervical cancer, etc. The invention has the advantages of simple prescription, convenient production, thus offering patients convenience for medicine taking with remarkable effect as well as great application value.

Description

A kind of Chinese medicine composition for the treatment of breast carcinoma and cervical cancer and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method thereof, the technical field of pharmaceuticals that belonging to enriches blood invigorated blood circulation and stimulated the menstrual flow brokenly disease.Cure mainly married woman's amenia, diseases such as long-pending piece pain, breast carcinoma and cervical cancer in the abdomen.
Background technology
Breast carcinoma and cervical cancer are a kind of frequently-occurring diseases, and its sickness rate presents ascendant trend year by year in recent years.Cancer be body under various carcinogenic factor effects, the cellular abnormality hypertrophy of local organization and the lump that forms, clinical symptoms shows as tumor location pain, heating and anemia.The traditional Chinese medical science thinks that tumor all shows as qi depression to blood stasis and pyretic toxicity stasis of blood knot mostly, therefore treats breast carcinoma and cervical cancer then adopts the Chinese herbal medicine of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, vigorate qi and replenish the blood, dissipating phlegm and resolving masses and the disease of stimulating the menstrual flow brokenly to carry out Comprehensive Treatment.
The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diseases such as breast carcinoma and cervical cancer.Through clinical treatment observation, find this pharmaceutical composition disease of invigorating blood circulation and stimulate the menstrual flow broken for enriching blood, cure mainly married woman's amenia, long-pending piece pains and other diseases has splendid therapeutic effect in the abdomen, has alleviated the symptom of various discomforts, and the while is not found untoward reaction.
Summary of the invention
The object of the present invention is to provide a kind of evident in efficacy, taking convenience, side effect little, can be fit to the treatment breast carcinoma of taking for a long time and the Chinese medicinal capsule of cervical cancer.
The present invention also provides the preparation method of this Chinese medicinal capsule.
Chinese medicine composition of the present invention can be used for treating diseases such as breast carcinoma and cervical cancer, and the effect that having enriches blood invigorated blood circulation and stimulated the menstrual flow brokenly disease cures mainly married woman's amenia, diseases such as long-pending piece pain, breast carcinoma and cervical cancer in the abdomen.
Chinese medicine composition of the present invention is prepared from by the following weight parts proportion raw material:
10~200 parts of 100~800 parts of Rhizoma Cyperis, 100~700 parts of Rhizoma Curcumae, 100~700 parts of Radix Angelicae Sinensis, 100~700 parts of rhizoma sparganic, 100~500 parts of Radix Paeoniae Rubra, 100~500 parts of the Radix Paeoniae Albas, 100~500 parts on Pericarpium Citri Reticulatae Viride, 50~400 parts of the Radixs Linderae, 10~300 parts on Flos Carthami, 10~300 parts of Lignum Sappans, 10~300 parts of Cortex Cinnamomi, 10~300 parts of Fructus Psoraleaes and the Radixs Astragali.
Chinese medicine composition of the present invention is prepared from by following preferred weight part proportion raw material:
20~100 parts of 200~600 parts of Rhizoma Cyperis, 200~500 parts of Rhizoma Curcumae, 200~500 parts of Radix Angelicae Sinensis, 200~500 parts of rhizoma sparganic, 150~400 parts of Radix Paeoniae Rubra, 150~400 parts of the Radix Paeoniae Albas, 150~400 parts on Pericarpium Citri Reticulatae Viride, 100~300 parts of the Radixs Linderae, 50~200 parts on Flos Carthami, 50~200 parts of Lignum Sappans, 50~150 parts of Cortex Cinnamomi, 50~150 parts of Fructus Psoraleaes and the Radixs Astragali.
Chinese medicine composition of the present invention is prepared from by following optimum weight part proportion raw material:
50 parts of 400 parts of Rhizoma Cyperis, 300 parts of Rhizoma Curcumae, 300 parts of Radix Angelicae Sinensis, 300 parts of rhizoma sparganic, 250 parts of Radix Paeoniae Rubra, 250 parts of the Radix Paeoniae Albas, 250 parts on Pericarpium Citri Reticulatae Viride, 200 parts of the Radixs Linderae, 100 parts on Flos Carthami, 100 parts of Lignum Sappans, 70 parts of Cortex Cinnamomi, 70 parts of Fructus Psoraleaes and the Radixs Astragali.
Chinese medicinal capsule of the present invention can be prepared from by following method:
1, Rhizoma Cyperi, Rhizoma Curcumae and the rhizoma sparganic of described weight portion is ground into coarser powder with the Radix Angelicae Sinensis and the Radix Linderae after with the vinegar parch, 70% alcohol dipping percolation after 48 hours leaves standstill after-filtration, gets supernatant concentration and becomes extractum 1;
2, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride and the Lignum Sappan with described weight portion is ground into coarser powder, with 80% alcohol heating reflux twice, and each each 2 hours, filter, be condensed into extractum 2;
3, the Flos Carthami of residue and described weight portion, Cortex Cinnamomi, Fructus Psoraleae and the Radix Astragali etc. decoct with water three times, and each each 2 hours, to filter, filtrate concentrates the back and merges with extractum 1 and extractum 2, and spray drying behind the mixing incapsulates and gets final product.
Prescription of the present invention is made up of 13 flavor Chinese medicines such as Rhizoma Cyperi, Rhizoma Curcumae, Radix Angelicae Sinensis, rhizoma sparganic, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride, the Radix Linderae, Flos Carthami, Lignum Sappan, Cortex Cinnamomi, Fructus Psoraleae and the Radix Astragali.Modern pharmacological research shows: with Rhizoma Cyperi, Rhizoma Curcumae with when being classified as monarch drug, Rhizoma Cyperi can liver-smoothing, qi-regulating in the side, menstruction regulating and pain relieving, normal and Radix Angelicae Sinensis and Pericarpium Citri Reticulatae Viride compatibility be used for the treating the liver stagnation of QI due to tying menoxenia, abdominal pain during menstruation, distending pain of the breast or caking etc. is arranged; Rhizoma Curcumae can removing blood stasis circulation of qi promoting, the removing food stagnancy pain relieving, both kind removing blood stasis, benefaction gas pain relieving again is used to control amenorrhea stomachache with Radix Angelicae Sinensis and rhizoma sparganic compatibility, and De lumps in the chest and abdomen due to piece and the stagnation of QI and blood is arranged in the abdomen; Radix Angelicae Sinensis can be enriched blood and be invigorated blood circulation, and is used for all diseases of blood deficiency; With rhizoma sparganic, Radix Paeoniae Rubra, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride and the Radix Linderae is ministerial drug, the circulation of qi promoting of rhizoma sparganic energy removing blood stasis, and the removing food stagnancy pain relieving is used for the depressed serious symptom of blood stasis; Radix Paeoniae Rubra can clearing away heat and cooling blood, and stasis-dispelling and pain-killing is used for amenorrhea stimulate the menstrual flow, lumps in the chest and abdomen and sore, carbuncle and painful swelling etc.; Radix Paeoniae Alba energy nourishing blood for regulating menstruation, the suppressing the hyperactive liver pain relieving, astringing YIN to stop sweating, being used for the blood deficiency or the deficiency of YIN has hot menoxenia etc.; Pericarpium Citri Reticulatae Viride energy soothing liver-QI dispelling the stagnated QI, removing food stagnancyization stagnates, and is used for depression of liver-QI and qi stagnation blood stasis etc., controls distending pain of the breast and caking etc.; Radix Linderae energy promoting the circulation of QI to relieve pain, warming kidney for dispelling cold; With Flos Carthami, Lignum Sappan, Cortex Cinnamomi, Fructus Psoraleae and the Radix Astragali is adjuvant drug, Flos Carthami energy promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; Lignum Sappan can be invigorated blood circulation and be cured the wound, and blood stasis dispelling stimulates the menstrual flow, reducing swelling and alleviating pain; It is supporing yang that Cortex Cinnamomi can be mended fire, dispersing cold for relieving pain, warming the meridian and promoting blood circulation; Fructus Psoraleae energy reinforcing the kidney and supporting YANG, warm spleen antidiarrheal, helping inspiration to relieve asthma; Radix Astragali energy tonifying Qi and lifting yang, inducing diuresis to remove edema, holder skin ulcer granulation promoting.All medicine compatibilities are played the effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, vigorate qi and replenish the blood, dissipating phlegm and resolving masses and the disease of stimulating the menstrual flow brokenly altogether.
Pharmaceutical composition of the present invention shows through clinical experiment, we's taking convenience, side effect be little, can be fit to take for a long time, patient's taking convenience, splendid therapeutical effect is arranged, alleviate the symptom of various discomforts, can be used for treating diseases such as breast carcinoma and cervical cancer, the effect that having enriches blood invigorated blood circulation and stimulated the menstrual flow brokenly disease, cure mainly married woman's amenia, diseases such as long-pending piece pain, breast carcinoma and cervical cancer in the abdomen.
Through clinical experiment, this Chinese medicinal capsule carries out observation of curative effect to 111 routine patient with breast cancers, finds that effective percentage reaches 85.59%, 65 routine cervical cancer patient and carries out observation of curative effect, finds that effective percentage reaches 87.69%, therefore is with a wide range of applications.
The specific embodiment
Embodiment 1
Rhizoma Cyperi 200g, Rhizoma Curcumae 200g, Radix Angelicae Sinensis 200g, rhizoma sparganic 200g, Radix Paeoniae Rubra 200g, Radix Paeoniae Alba 200g, Pericarpium Citri Reticulatae Viride 200g, Radix Linderae 200g, Flos Carthami 100g, Lignum Sappan 100g, Cortex Cinnamomi 100g, Fructus Psoraleae 100g and Radix Astragali 100g.Rhizoma Cyperi, Rhizoma Curcumae and the rhizoma sparganic of described weight portion is ground into coarser powder with the Radix Angelicae Sinensis and the Radix Linderae after with the vinegar parch, and 70% alcohol dipping percolation after 48 hours leaves standstill after-filtration, gets supernatant concentration and becomes extractum 1; Radix Paeoniae Rubra, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride and the Lignum Sappan of described weight portion are ground into coarser powder, with 80% alcohol heating reflux twice, each each 2 hours, filter, be condensed into extractum 2; The Flos Carthami of residue and described weight portion, Cortex Cinnamomi, Fructus Psoraleae and the Radix Astragali etc. decoct with water three times, and each each 2 hours, to filter, filtrate concentrates the back and merges with extractum 1 and extractum 2, and spray drying behind the mixing incapsulates and gets final product.Every capsules 0.5g.Instructions of taking: obey every day 3 times, each 5 before the meal.
Embodiment 2
Rhizoma Cyperi 300g, Rhizoma Curcumae 300g, Radix Angelicae Sinensis 300g, rhizoma sparganic 300g, Radix Paeoniae Rubra 100g, Radix Paeoniae Alba 100g, Pericarpium Citri Reticulatae Viride 100g, Radix Linderae 100g, Flos Carthami 50g, Lignum Sappan 50g, Cortex Cinnamomi 50g, Fructus Psoraleae 50g and Radix Astragali 50g.Rhizoma Cyperi, Rhizoma Curcumae and the rhizoma sparganic of described weight portion is ground into coarser powder with the Radix Angelicae Sinensis and the Radix Linderae after with the vinegar parch, and 70% alcohol dipping percolation after 48 hours leaves standstill after-filtration, gets supernatant concentration and becomes extractum 1; Radix Paeoniae Rubra, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride and the Lignum Sappan of described weight portion are ground into coarser powder, with 80% alcohol heating reflux twice, each each 2 hours, filter, be condensed into extractum 2; The Flos Carthami of residue and described weight portion, Cortex Cinnamomi, Fructus Psoraleae and the Radix Astragali etc. decoct with water three times, and each each 2 hours, to filter, filtrate concentrates the back and merges with extractum 1 and extractum 2, and spray drying behind the mixing incapsulates and gets final product.Every capsules 0.5g.Instructions of taking: obey every day 3 times, each 5 before the meal.
Embodiment 3
Rhizoma Cyperi 400g, Rhizoma Curcumae 300g, Radix Angelicae Sinensis 300g, rhizoma sparganic 300g, Radix Paeoniae Rubra 250g, Radix Paeoniae Alba 250g, Pericarpium Citri Reticulatae Viride 250g, Radix Linderae 200g, Flos Carthami 100g, Lignum Sappan 100g, Cortex Cinnamomi 70g, Fructus Psoraleae 70g and Radix Astragali 50g.Rhizoma Cyperi, Rhizoma Curcumae and the rhizoma sparganic of described weight portion is ground into coarser powder with the Radix Angelicae Sinensis and the Radix Linderae after with the vinegar parch, and 70% alcohol dipping percolation after 48 hours leaves standstill after-filtration, gets supernatant concentration and becomes extractum 1; Radix Paeoniae Rubra, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride and the Lignum Sappan of described weight portion are ground into coarser powder, with 80% alcohol heating reflux twice, each each 2 hours, filter, be condensed into extractum 2; The Flos Carthami of residue and described weight portion, Cortex Cinnamomi, Fructus Psoraleae and the Radix Astragali etc. decoct with water three times, and each each 2 hours, to filter, filtrate concentrates the back and merges with extractum 1 and extractum 2, and spray drying behind the mixing incapsulates and gets final product.Every capsules 0.5g.Instructions of taking: obey every day 3 times, each 5 before the meal.

Claims (4)

1. Chinese medicine composition for the treatment of breast carcinoma and cervical cancer is characterized in that the medicine material that raw material contains following weight portion proportioning forms: 10~200 parts of 100~800 parts of Rhizoma Cyperis, 100~700 parts of Rhizoma Curcumae, 100~700 parts of Radix Angelicae Sinensis, 100~700 parts of rhizoma sparganic, 100~500 parts of Radix Paeoniae Rubra, 100~500 parts of the Radix Paeoniae Albas, 100~500 parts on Pericarpium Citri Reticulatae Viride, 50~400 parts of the Radixs Linderae, 10~300 parts on Flos Carthami, 10~300 parts of Lignum Sappans, 10~300 parts of Cortex Cinnamomi, 10~300 parts of Fructus Psoraleaes and the Radixs Astragali.
2. require described Chinese medicine composition according to right 1, it is characterized in that the medicine material that raw material contains following weight portion proportioning forms: 20~100 parts of 200~600 parts of Rhizoma Cyperis, 200~500 parts of Rhizoma Curcumae, 200~500 parts of Radix Angelicae Sinensis, 200~500 parts of rhizoma sparganic, 150~400 parts of Radix Paeoniae Rubra, 150~400 parts of the Radix Paeoniae Albas, 150~400 parts on Pericarpium Citri Reticulatae Viride, 100~300 parts of the Radixs Linderae, 50~200 parts on Flos Carthami, 50~200 parts of Lignum Sappans, 50~150 parts of Cortex Cinnamomi, 50~150 parts of Fructus Psoraleaes and the Radixs Astragali.
3. require the Chinese medicine composition of described treatment breast carcinoma and cervical cancer according to right 1,2, it is characterized in that the optimised quantity of each raw material is: 50 parts of 400 parts of Rhizoma Cyperis, 300 parts of Rhizoma Curcumae, 300 parts of Radix Angelicae Sinensis, 300 parts of rhizoma sparganic, 250 parts of Radix Paeoniae Rubra, 250 parts of the Radix Paeoniae Albas, 250 parts on Pericarpium Citri Reticulatae Viride, 200 parts of the Radixs Linderae, 100 parts on Flos Carthami, 100 parts of Lignum Sappans, 70 parts of Cortex Cinnamomi, 70 parts of Fructus Psoraleaes and the Radixs Astragali.
4. require described medicine according to right 3, Rhizoma Cyperi, Rhizoma Curcumae and the rhizoma sparganic of described weight portion is ground into coarser powder with the Radix Angelicae Sinensis and the Radix Linderae after with the vinegar parch, 70% alcohol dipping percolation after 48 hours leaves standstill after-filtration, gets supernatant concentration and becomes extractum 1; Radix Paeoniae Rubra, the Radix Paeoniae Alba, Pericarpium Citri Reticulatae Viride and the Lignum Sappan of described weight portion are ground into coarser powder, with 80% alcohol heating reflux twice, each each 2 hours, filter, be condensed into extractum 2; The Flos Carthami of residue and described weight portion, Cortex Cinnamomi, Fructus Psoraleae and the Radix Astragali etc. decoct with water three times, and each each 2 hours, to filter, filtrate concentrates the back and merges with extractum 1 and extractum 2, and spray drying behind the mixing incapsulates and gets final product.Every capsules 0.5g.
CNA200710178348XA 2007-11-29 2007-11-29 Chinese traditional medicine composite for breast cancer and cervical carcinoma and preparation method thereof Pending CN101204552A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069194A (en) * 2013-03-26 2014-10-01 成都地奥集团天府药业股份有限公司 A traditional Chinese medicine composition having anticancer effects and a preparing method and uses thereof
CN104383467A (en) * 2014-12-15 2015-03-04 许莹 Traditional Chinese medicine for treating liver-qi depression type cervical cancer and preparation method of traditional Chinese medicine
CN104491719A (en) * 2014-12-16 2015-04-08 牟慧芳 Traditional Chinese medicine composition for treating cervical cancers
CN104623450A (en) * 2015-03-16 2015-05-20 徐若曾 Traditional Chinese medicine preparation for treating breast cancer
CN104623451A (en) * 2015-03-16 2015-05-20 徐若曾 Traditional Chinese medicine composition for treating breast cancer
CN104740561A (en) * 2015-03-09 2015-07-01 王艳君 Phlegm-eliminating and stasis-removing medicine for removing breast tumor and preparation method of phlegm-eliminating and stasis-removing medicine

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104069194A (en) * 2013-03-26 2014-10-01 成都地奥集团天府药业股份有限公司 A traditional Chinese medicine composition having anticancer effects and a preparing method and uses thereof
CN104069194B (en) * 2013-03-26 2017-03-29 成都地奥集团天府药业股份有限公司 A kind of Chinese medicine composition with antitumaous effect and its production and use
CN104383467A (en) * 2014-12-15 2015-03-04 许莹 Traditional Chinese medicine for treating liver-qi depression type cervical cancer and preparation method of traditional Chinese medicine
CN104491719A (en) * 2014-12-16 2015-04-08 牟慧芳 Traditional Chinese medicine composition for treating cervical cancers
CN104740561A (en) * 2015-03-09 2015-07-01 王艳君 Phlegm-eliminating and stasis-removing medicine for removing breast tumor and preparation method of phlegm-eliminating and stasis-removing medicine
CN104623450A (en) * 2015-03-16 2015-05-20 徐若曾 Traditional Chinese medicine preparation for treating breast cancer
CN104623451A (en) * 2015-03-16 2015-05-20 徐若曾 Traditional Chinese medicine composition for treating breast cancer

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