CN102793845A - Chinese medicinal composition for treating climacteric syndrome - Google Patents

Chinese medicinal composition for treating climacteric syndrome Download PDF

Info

Publication number
CN102793845A
CN102793845A CN2012103242821A CN201210324282A CN102793845A CN 102793845 A CN102793845 A CN 102793845A CN 2012103242821 A CN2012103242821 A CN 2012103242821A CN 201210324282 A CN201210324282 A CN 201210324282A CN 102793845 A CN102793845 A CN 102793845A
Authority
CN
China
Prior art keywords
parts
climacteric syndrome
medicinal composition
chinese medicinal
chinese medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN2012103242821A
Other languages
Chinese (zh)
Other versions
CN102793845B (en
Inventor
王凤梅
李百荣
朱洪亮
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhang Aili
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201210324282.1A priority Critical patent/CN102793845B/en
Publication of CN102793845A publication Critical patent/CN102793845A/en
Application granted granted Critical
Publication of CN102793845B publication Critical patent/CN102793845B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The invention discloses a Chinese medicinal composition for treating a climacteric syndrome. The Chinese medicinal composition is prepared from large whorlleaf stonecrop herb, pig nail, grifola frondosa, dwarf lilyturf root, deer-horn glue, lily, rosemary, common anemarrhena, Chinese data and red-rooted salvia root. The Chinese medicinal composition can be clinically applied to treatment of the climacteric syndrome.

Description

A kind of Chinese medicine composition of treating climacteric syndrome
Technical field
The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition of treating climacteric syndrome.
Background technology
Climacteric syndrome refers to before and after the postmenopausal women because a series of bodies and spiritual mental symptoms due to the estrogen decrease.Owing to society, life, operating pressure increase, the climacteric women symptom is obvious, bears heavy stress, has a strong impact on the family life harmony in recent years.Most women can reach new balance and no conscious sympton also has the some women symptom obvious through neuroendocrine self regulation, needs Drug therapy to come relief of symptoms.Doctor trained in Western medicine adopts the complementing estrogen treatment more, like nilestriol, livial etc., but its clinical symptoms improvement rate and not really desirable.Long-term practice through the inventor draws, and Chinese medicine is controlled climacteric syndrome and had better effect, obtains good effect.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, to the Chinese medicine composition of the treatment climacteric syndrome of human non-toxic side effect.
The objective of the invention is to realize like this; According to Chinese medical theory; Utilize the unique property of medicine of Chinese medicine, adopt Paraboea dictyoneura (Hance) B. L (Burtt) grass, Unguis Sus domestica, Grifola frondosa, Radix Ophiopogonis, Colla cornus cervi, Bulbus Lilii, Herba Rosmarini Officinalis, the Rhizoma Anemarrhenae, Fructus Jujubae, Radix Salviae Miltiorrhizae be according to certain compatibility requirement, through and being processed into.
Preparing Chinese medicine composition of the present invention is processed by following raw material medicaments: Paraboea dictyoneura (Hance) B. L (Burtt) grass 30-50 part, Unguis Sus domestica 20-40 part, Grifola frondosa 20-40 part, Radix Ophiopogonis 20-30 part, Colla cornus cervi 15-25 part, Bulbus Lilii 15-25 part, Herba Rosmarini Officinalis 10-20 part, Rhizoma Anemarrhenae 10-20 part, Fructus Jujubae 8-15 part, Radix Salviae Miltiorrhizae 8-15 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 40 parts of Paraboea dictyoneura (Hance) B. L (Burtt) grass, 30 parts of Unguis Sus domesticas, 25 parts of Grifola frondosa, 25 parts of Radix Ophiopogonis, 22 parts of Colla cornus cervis, 22 parts of Bulbus Liliies, 13 parts of Herba Rosmarini Officinaliss, 17 parts of the Rhizoma Anemarrhenaes, 12 parts in Fructus Jujubae, 12 parts of Radix Salviae Miltiorrhizaes.
The pharmacological action of Chinese medicine of the present invention is following:
Paraboea dictyoneura (Hance) B. L (Burtt) grass: sweet, puckery, be slightly cold.Mind calming, spleen invigorating, dissipating blood stasis, hemostasis.Be used for palpitation and insomnia, hepatosplenomegaly, uterine prolapse, frequent fetal movement, proctoptosis, spitting of blood, treating swelling and pain by traumatic injury, traumatic hemorrhage, diseases such as herpes zoster.
Unguis Sus domestica: salty, cold.Return stomach, large intestine channel.Eliminating phlegm to relieve asthma, removing toxic substances and promoting granulation.Clinical be used for the cough pant acute appendicitis, anal fistula, chilblain, climacteric syndrome etc.
Grifola frondosa: sweet, flat.Replenishing QI to invigorate the spleen, tonify deficiency are set upright.Be used for deficiency of the spleen causing weakness of QI, fatigue and asthenia, spiritlessness and sparing of words; Diet reduces, abdominal distention after meal; The person that has the above-mentioned symptom after tumor patient radiotherapy or the chemotherapy.
Radix Ophiopogonis: sweet, little hardship, be slightly cold.Return lung, stomach, heart channel.Nourishing YIN and moistening the lung, reinforcing stomach reg fluid, relieving restlessness clears away heart-fire.Cure mainly dryness of the lung dry cough, the deficiency of YIN, Tianjin wound is thirsty, cards such as vexed insomnia.
Colla cornus cervi: sweet, salty, warm.Return liver, kidney channel.The kidney invigorating and essence nourishing, nourishing blood and preventing abortion, hemostasis.It is thin and weak to cure mainly asthenia, dizziness and tinnitus, cards such as soreness of the waist and knees.
Bulbus Lilii: sweet, little hardship is slightly cold GUIXIN, lung meridian.Nourishing YIN to relieve dryness, clearing away heart-fire for tranquillization.Cure mainly the fidgets due to deficiency palpitation with fear due to unsuccessful of deficiency of YIN chronic cough or feelings will, insomnia and dreamful sleep.
Herba Rosmarini Officinalis: hot, warm.Diaphoresis, spleen invigorating, calm the nerves, pain relieving.Be used for various headaches, prevent early stage alopecia, climacteric syndrome etc.
The Rhizoma Anemarrhenae: sweet, bitter, cold, return lung, stomach, kidney channel.Clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.Be used for calentura excessive thirst, cough due to lung-heat.Fructus Jujubae: sweet, warm.Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind relaxes the property of medicine.Be used for insufficiency of the spleen anorexia and loose stool, fatigue and weakness, blood deficiency and yellow complexion and women's internal organs, mind is uneasy, protection healthy energy etc.
Radix Salviae Miltiorrhizae: bitter, be slightly cold.GUIXIN, Liver Channel.Promoting blood flow to regulate menstruation, the removing heat from blood eliminating carbuncle is calmed the nerves.The ambition, epigastric pain that are used for blood stasis is Ji lumps in the chest and abdomen, rheumatic arthralgia, skin infection carbuncle etc.
Climacteric syndrome, the traditional Chinese medical science are referred to as " menopausal syndrome ", kidney qi degradation before and after the postmenopausal women, and menses will exhaust; Essence and blood declines few, is individual character physiology degenerative process gradually, and its pathogenesis is complicated; Clinical manifestation is different, though primary disease is not normal with function of five internal organs, it is relevant that yang blood and qi is unbalance; But, lack when mainly coming from Liver and kidney two dirty essence and blood void, and deterioration and imbalance occur according to women's physiology and pathological characteristic.The spleen invigorating of Paraboea dictyoneura (Hance) B. L (Burtt) grass mind calming, blood circulation promoting and blood stasis dispelling among the present invention, be monarch drug, the Unguis Sus domestica eliminating phlegm to relieve asthma, the pathogenic fire reducing that detoxifies, Grifola frondosa replenishing QI to invigorate the spleen, tonify deficiency are set upright; Be ministerial drug, YIN nourishing Radix Ophiopogonis, the relieving restlessness of promoting the production of body fluid, clear away heart-fire, Colla cornus cervi the kidney invigorating and essence nourishing, Bulbus Lilii nourishing YIN to relieve dryness; Clearing away heart-fire for tranquillization, is calmed the nerves Rhizoma Anemarrhenae clearing away heat-fire, nourshing Yin and drynsessmoistening prescription at the Herba Rosmarini Officinalis spleen invigorating; The Fructus Jujubae invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, Radix Salviae Miltiorrhizae are invigorated blood circulation, are calmed the nerves.All medicines share, and play nourishing the liver and kidney altogether, nourishing YIN to lower pathogenic fire, and the merit that relieving restlessness is calmed the nerves reaches the effect of treating climacteric syndrome.
Chinese medicine composition of the present invention was in 2008 to 2010 clinical observation climacteric syndrome 80 routine patients, and clinical report is following:
1, physical data
Among the 80 routine patients, age 43-55 year, the course of disease is many at 3 months to 2 years, 50 years old mean age.
2, diagnostic criteria
" traditional Chinese medical science disease diagnosis criterion of therapeutical effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:
Age of onset is generally in 45-55 one full year of life, and before and after the menopause, disease is seen menoxenia, and hectic fever is flushing, warms sweating, and is excited; Abnormal emotion-thought, paresthesia of skin, soreness of the waist and knees, dizziness headache, tinnitus, irritated irritability; Binocular dryness, dry mouth and throat, insomnia forgetfulness, red tongue few tongue, thready and rapid pulse or stringy and thready pulse.
3, Therapeutic Method
3.1 prescription: Paraboea dictyoneura (Hance) B. L (Burtt) grass 40g, Unguis Sus domestica 30g, Grifola frondosa 25g, Radix Ophiopogonis 25g, Colla cornus cervi 22g, Bulbus Lilii 22g, Herba Rosmarini Officinalis 13g, Rhizoma Anemarrhenae 17g, Fructus Jujubae 12g, Radix Salviae Miltiorrhizae 12g.
3.2 preparation and method for using: said medicine is processed decoction by common process, and 1 dose of every day, every day 2 times, 15 days was 1 course of treatment.
4, therapeutic outcome:
4.1 formulate with reference to " traditional Chinese medical science disease diagnosis criterion of therapeutical effect ":
Cure: clinical symptoms reduces 90% and reaches the above and lasting person repeatedly that do not have more than 6 months;
Effectively: clinical symptoms reduces 30%-89% and 6 months with interior nothing person repeatedly;
Invalid: clinical symptoms reduces below 29%.
4.2 result: among the 80 routine patients, clinical cure 54 examples, effective 20 examples, invalid 6 examples, total effective rate is 92.5%.
5, model case
5.1 Lee, the woman, 49 years old, patient's readme before 1 year menstruation begin disorder, delay more.The emotion agitation appears in the patient since 3 months, dizziness and tinnitus, and the hectic fever hyperhidrosis, the soreness of waist is weak, and dream is prone to more is waken up.Pale complexion after diagnosing, spirit depressing, dizziness and tinnitus, vexed difficulty is slept, and dream is prone to more is waken up, and soreness of waist body is tired, and light red tongue, tongue are white, and deep-thready pulse is diagnosed as climacteric syndrome.Take medicine of the present invention, treat 1 course of treatment, symptom obviously alleviates, and the soreness of waist is weak, and vexed insomnia obviously improves, and perspires and reduces.Continue to take 2 courses of treatment, recovery from illness is followed up a case by regular visits to and was not seen recurrence in 1 year.
5.2 fourth, woman, 48 years old.Patient's disorder in the period, 2 was passed through once in every 15-18 days, continued 4-5 days; Amount is many, and color is red, and piece is arranged; And companion dizziness and blurred vision, tinnitus, cardiopalmus, insomnia, irritated irritability, warm perspiration, it is not obvious once to obey effect of drugs such as oryzanol, vitamin, stable, GENGNIANAN.Current symptom: the confusion of the menstrual cycle, dizziness, cardiopalmus, forgetful, insomnia, tinnitus, warm perspiration, irritated irritability, sentimental wound, light red tongue, the little Huang of thin lingual fur, stringy and thready pulse.Take medicine of the present invention, 1 dose of every day, after 1 course of treatment, symptom is clearly better, and continues to take 2 courses of treatment, and recovery from illness is followed up a case by regular visits to and do not seen recurrence in 1 year.
5.3 Yin, woman, 49 years old.The patient menstruation occurs successively irregularly over 1 year, and with palpitation and insomnia, spiritlessness and weakness, dysphoria, warm sweating, hypomnesis, poor appetite, constipation with dry stool, 5-6 day delegation, its body of the tongue is light red, white and thin fur, stringy and thready pulse.Be diagnosed as climacteric syndrome.Take medicine of the present invention, 1 dose of every day, after 1 course of treatment, symptom is clearly better, and continues to take 1 course of treatment, and recovery from illness is followed up a case by regular visits to and do not seen recurrence in 6 months.
The specific embodiment
Below in conjunction with embodiment the present invention is further described, following this embodiment only is used to the present invention is described and the present invention is not limited.
Embodiment 1, a kind of Chinese medicine composition of treating climacteric syndrome, be by Paraboea dictyoneura (Hance) B. L (Burtt) grass 30g, Unguis Sus domestica 20g, Grifola frondosa 20g, Radix Ophiopogonis 20g, Colla cornus cervi 15g, Bulbus Lilii 15g, Herba Rosmarini Officinalis 10g, Rhizoma Anemarrhenae 10g, Fructus Jujubae 8g, Radix Salviae Miltiorrhizae 8g process.
Embodiment 2, a kind of Chinese medicine composition of treating climacteric syndrome, be by Paraboea dictyoneura (Hance) B. L (Burtt) grass 40g, Unguis Sus domestica 30g, Grifola frondosa 25g, Radix Ophiopogonis 25g, Colla cornus cervi 22g, Bulbus Lilii 22g, Herba Rosmarini Officinalis 13g, Rhizoma Anemarrhenae 17g, Fructus Jujubae 12g, Radix Salviae Miltiorrhizae 12g process.
Embodiment 3, a kind of Chinese medicine composition of treating climacteric syndrome, be by Paraboea dictyoneura (Hance) B. L (Burtt) grass 50g, Unguis Sus domestica 40g, Grifola frondosa 40g, Radix Ophiopogonis 30g, Colla cornus cervi 25g, Bulbus Lilii 25g, Herba Rosmarini Officinalis 20g, Rhizoma Anemarrhenae 20g, Fructus Jujubae 15g, Radix Salviae Miltiorrhizae 15g process.

Claims (2)

1. Chinese medicine composition of treating climacteric syndrome is characterized in that it is to be processed by following raw material medicaments: Paraboea dictyoneura (Hance) B. L (Burtt) grass 30-50 part, Unguis Sus domestica 20-40 part, Grifola frondosa 20-40 part, Radix Ophiopogonis 20-30 part, Colla cornus cervi 15-25 part, Bulbus Lilii 15-25 part, Herba Rosmarini Officinalis 10-20 part, Rhizoma Anemarrhenae 10-20 part, Fructus Jujubae 8-15 part, Radix Salviae Miltiorrhizae 8-15 part.
2. Chinese medicine composition according to claim 1 is characterized in that it is to be processed by following raw material medicaments: 40 parts of Paraboea dictyoneura (Hance) B. L (Burtt) grass, 30 parts of Unguis Sus domesticas, 25 parts of Grifola frondosa, 25 parts of Radix Ophiopogonis, 22 parts of Colla cornus cervis, 22 parts of Bulbus Liliies, 13 parts of Herba Rosmarini Officinaliss, 17 parts of the Rhizoma Anemarrhenaes, 12 parts in Fructus Jujubae, 12 parts of Radix Salviae Miltiorrhizaes.
CN201210324282.1A 2012-08-26 2012-08-26 Traditional Chinese medicine composition for treating climacteric syndrome Expired - Fee Related CN102793845B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201210324282.1A CN102793845B (en) 2012-08-26 2012-08-26 Traditional Chinese medicine composition for treating climacteric syndrome

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201210324282.1A CN102793845B (en) 2012-08-26 2012-08-26 Traditional Chinese medicine composition for treating climacteric syndrome

Publications (2)

Publication Number Publication Date
CN102793845A true CN102793845A (en) 2012-11-28
CN102793845B CN102793845B (en) 2014-02-12

Family

ID=47193313

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201210324282.1A Expired - Fee Related CN102793845B (en) 2012-08-26 2012-08-26 Traditional Chinese medicine composition for treating climacteric syndrome

Country Status (1)

Country Link
CN (1) CN102793845B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758579A (en) * 2015-04-13 2015-07-08 吴秀娟 Traditional Chinese medicine for treating liver-kidney yin deficiency type climacteric syndrome
CN104888176A (en) * 2015-06-29 2015-09-09 孙小荣 Spleen deficiency type climacteric syndrome treatment traditional Chinese medicine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1102306A (en) * 1994-03-23 1995-05-10 王晓光 "Bazhen" lily bulb and preparing method
CN1215600A (en) * 1997-10-23 1999-05-05 黄付堂 Oral liquid for treating heart disease
CN102120006A (en) * 2010-10-13 2011-07-13 孔祥军 Chinese medicinal formula for treating insomnia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1102306A (en) * 1994-03-23 1995-05-10 王晓光 "Bazhen" lily bulb and preparing method
CN1215600A (en) * 1997-10-23 1999-05-05 黄付堂 Oral liquid for treating heart disease
CN102120006A (en) * 2010-10-13 2011-07-13 孔祥军 Chinese medicinal formula for treating insomnia

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104758579A (en) * 2015-04-13 2015-07-08 吴秀娟 Traditional Chinese medicine for treating liver-kidney yin deficiency type climacteric syndrome
CN104888176A (en) * 2015-06-29 2015-09-09 孙小荣 Spleen deficiency type climacteric syndrome treatment traditional Chinese medicine

Also Published As

Publication number Publication date
CN102793845B (en) 2014-02-12

Similar Documents

Publication Publication Date Title
CN102342992B (en) Chinese medicinal composition for treating insomnia and preparation method of preparation thereof
CN101874874A (en) Chinese medicinal preparation for treating helicobacter pylori concerned chronic gastritis and preparation method thereof
CN103330835A (en) Traditional Chinese medicine composition for treating climacteric syndromes
CN102716334B (en) Chinese medicinal composition for dispelling the cold and removing stasis
CN103550710A (en) Pueraria and fructus trichosanthis thoracic obstruction pill for treating coronary heart disease
CN102793845B (en) Traditional Chinese medicine composition for treating climacteric syndrome
CN103341118B (en) Medicament for treating threatened abortion and preparation method thereof
CN103550521A (en) Traditional Chinese medicine composition for treating night sweat
CN100374147C (en) Traditional Chinese medicine preparation for treating mammary gland hyperplasia
CN103007211B (en) Traditional Chinese medicine preparation for treating primary metrostaxis
CN1253196C (en) Medicine for treating colitis
CN102579607B (en) Chinese medicine composition for treating acne
CN102091163B (en) Chinese medicine composition for treating diabetic heart disease
CN104758579A (en) Traditional Chinese medicine for treating liver-kidney yin deficiency type climacteric syndrome
CN101850101B (en) Chinese medicinal composition for treating metrostaxis and preparation method thereof
CN105288413A (en) Medicine for treating infantile enuresis and preparation method thereof
CN101279007B (en) Chinese medicine for curing aconuresis
CN101116710A (en) Chinese traditional medicine preparations for treating postpartum dysuria
CN101204495B (en) Peroral Chinese traditional medicine composition for chronic nephritis
CN104288581A (en) Traditional Chinese medicine for treating threatened abortion
CN104117018A (en) Traditional Chinese medicine composition for treating coronary heart disease
CN108815226A (en) A kind of gynemetrics's drug and preparation method thereof for treating endocrine disorder
CN103845690A (en) Medicament for treating geriatric depression
CN102846772B (en) Navel-applied plaster for treating senile constipation and preparation method thereof
CN102512586A (en) Traditional Chinese drug preparation with function of yin and yang qi and blood nourishing

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: SUI LIPING

Free format text: FORMER OWNER: WANG FENGMEI

Effective date: 20140102

C41 Transfer of patent application or patent right or utility model
C53 Correction of patent of invention or patent application
CB03 Change of inventor or designer information

Inventor after: Sui Liping

Inventor after: Wang Fengmei

Inventor after: Zhao Jing

Inventor before: Wang Fengmei

Inventor before: Li Bairong

Inventor before: Zhu Hongliang

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: WANG FENGMEI LI BAIRONG ZHU HONGLIANG TO: SUI LIPING WANG FENGMEI ZHAO JING

TA01 Transfer of patent application right

Effective date of registration: 20140102

Address after: 262500 Shandong province Qingzhou City Linglong Mountain Road No. 4138 Weifang Yidu Central Hospital

Applicant after: Sui Liping

Address before: 262500 Qingzhou municipal hospital, 512 Wangfu East Street, Shandong, Qingzhou

Applicant before: Wang Fengmei

C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: FANGCHENGGANG CITY PORT DISTRICT BALANCE ELECTRONI

Free format text: FORMER OWNER: SUI LIPING

Effective date: 20141215

C41 Transfer of patent application or patent right or utility model
COR Change of bibliographic data

Free format text: CORRECT: ADDRESS; FROM: 262500 WEIFANG, SHANDONG PROVINCE TO: 538000 FANGCHENGGANG, GUANGXI ZHUANG AUTONOMOUS REGION

TR01 Transfer of patent right

Effective date of registration: 20141215

Address after: 538000 the Guangxi Zhuang Autonomous Region City, Fangchenggang port area before the intersection of the park and the intersection of the intersection of Dongxing Road, sea and sky are commercial and residential floor 11, No. 1108

Patentee after: FANGCHENGGANG CITY PORT DISTRICT BALANCE ELECTRONIC TECHNOLOGY CO., LTD.

Address before: 262500 Shandong province Qingzhou City Linglong Mountain Road No. 4138 Weifang Yidu Central Hospital

Patentee before: Sui Liping

CB03 Change of inventor or designer information

Inventor after: Zhang Aili

Inventor before: Sui Liping

Inventor before: Wang Fengmei

Inventor before: Zhao Jing

CB03 Change of inventor or designer information
TR01 Transfer of patent right

Effective date of registration: 20170807

Address after: 301705, Tianjin District, Wuqing City flag flag Road on the west side of the Ming Kam garden 3-5-102

Patentee after: Zhang Aili

Address before: 538000 the Guangxi Zhuang Autonomous Region City, Fangchenggang port area before the intersection of the park and the intersection of the intersection of Dongxing Road, sea and sky are commercial and residential floor 11, No. 1108

Patentee before: FANGCHENGGANG CITY PORT DISTRICT BALANCE ELECTRONIC TECHNOLOGY CO., LTD.

TR01 Transfer of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140212

Termination date: 20180826

CF01 Termination of patent right due to non-payment of annual fee