Summary of the invention
The object of this invention is to provide a kind of determined curative effect, have no side effect, technique simply treats umbilica sticking plaster of senile constipation and preparation method thereof.
The umbilica sticking plaster for the treatment of senile constipation of the present invention is by the crude drug of following parts by weight: 120~180 parts of Semen Prunis, 100~140 parts of Radix Adenophorae (Radix Glehniae), 120~180 parts of the Rhizoma Atractylodis Macrocephalaes, 100~140 parts of the Radix Paeoniae Albas, 120~180 parts of Radix et Rhizoma Rhei (processed with wine), 80~120 parts of Fructus Anisi Stellatis, 40~80 parts of Cortex Cinnamomis, 120~180 parts of Radix Angelicae Sinensis; Be equipped with adjuvant: 400~600 parts, 400~600 parts, vaseline, Cera Flava are made.
The preparation method of this umbilica sticking plaster comprises the following steps: a, Semen Pruni, Radix Adenophorae (Radix Glehniae), the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Radix et Rhizoma Rhei (processed with wine), Fructus Anisi Stellati, Cortex Cinnamomi, Radix Angelicae Sinensis are mixed according to described parts by weight, be ground into medicated powder more than 100 orders; B, the vaseline of described parts by weight is melted at 38 ℃~60 ℃, add the Cera Flava of described parts by weight, heat and completely after fusing, add the medicated powder of described parts by weight to 62 ℃~67 ℃, rapid stirring is even, cooling and get final product.
Preferably, umbilica sticking plaster of the present invention can be by the crude drug of following parts by weight: 150 parts of Semen Prunis, 120 parts of Radix Adenophorae (Radix Glehniae), 150 parts of the Rhizoma Atractylodis Macrocephalaes, 120 parts of the Radix Paeoniae Albas, 150 parts of Radix et Rhizoma Rhei (processed with wine), 100 parts of Fructus Anisi Stellatis, 60 parts of Cortex Cinnamomis, 150 parts of Radix Angelicae Sinensis; Be equipped with adjuvant: 500 parts, 500 parts, vaseline, Cera Flava are made.
Semen Pruni is moisturized laxation, the therapeutic method to keep the adverse QI flowing downwards, and diuretic, for intestine-dryness due to consumption of fluid, stagnation of QI due to dyspepsia, abdominal distention constipation, edema, beriberi, dysuria; Radix Adenophorae (Radix Glehniae) clearing away heat and nourishing YIN, nourishing the lung to arrest cough, cures mainly tracheitis, pertussis, cough due to lung-heat, coughs up phlegm yellow thick; Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive, for insufficiency of the spleen lack of appetite, abdominal distention have loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement; The pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver, nourishing blood for regulating menstruation, astringing YIN to stop sweating,, hypochondriac pain dizzy for having a headache, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat; It is supporing yang that Cortex Cinnamomi is mended fire, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow; Warming the spleen and stomach, removing accumulated cold, promoting blood circulation; Fructus Anisi Stellati cold expelling, regulates the flow of vital energy, and pain relieving, for colic of cold type stomachache, chills and pain of the waist and kness, gastrofrigid vomiting, epigastric pain, the disturbance of lower legs due to pathogenic cold and dampness; Chinese angelica blood supplementing is invigorated blood circulation, menstruction regulating and pain relieving, and loosening bowel to relieve constipation, for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores; The clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system of Radix et Rhizoma Rhei (processed with wine), for conjunctival congestion pharyngeal swelling, gingivitis.All medicine compatibilities, supplementing QI for promoting the production of body fluid, loosening bowel to relieve constipation, the obstructed effect for the treatment of senile constipation is remarkable.
The present invention makes umbilica sticking plaster by said medicine and uses; compared with prior art there is following characteristics: Cera Flava has the effect of astringent therapy, granulation promoting, pain relieving, removing toxic substances; vaseline has water proofing property, is a kind of extraordinary moisturizing articles for use, the raw material of using for preparing medical ointment and skin care ointment.The substrate (adjuvant) that it adopts as umbilica sticking plaster, chemical stabilization, and this umbilica sticking plaster has the feature of principal agent high volatility, preparation technology is easy, be conducive to umbilicus penetrates and absorbs, especially to skin of umbilicus place without anaphylaxis, more have no side effect.In addition the bad toxic and side effects that can avoid some oral drugs to bring generations such as patient's liver kidneys.
Relevant clinical data is as follows: 60~70 years old age, 51 examples in 90 routine cases, 71~80 years old 39 example.Be divided at random three groups, every group of 30 examples, three groups of case physical data are learned by statistics processing there was no significant difference (P > 0.05) and are had comparability.
The efficacy assessment standard that all cases all adopt by reference in the < < new Chinese medicine guideline of clinical investigations > > that < < traditional Chinese medical science disease Standardization of diagnosis and curative effect (ZY/T001.1~001.9~94) > > develops and publishes about the diagnostic criteria of constipation and Ministry of Health of the People's Republic of China in 1993 is made a definite diagnosis.
Diagnostic criteria: be because of deficiency of both vital energy and Yin, or dryness-heat stagnating in the interior, due to internal organs gas is not smooth, with infrequent defecation time lengthening, constipation with dry stool is difficult to resolve the disease into main clinical manifestation, often refers to habitual constipation.All cases all meets the old diagnostic criteria about old QI and blood deficiency constipation of Xu: disease is seen constipation with dry stool, defecation inability, and lusterless complexion, deficiency of QI with disinclination to talk, insomnia forgetfulness, rectal tenesmus is uncomfortable, and pale tongue with thin fur is white, thready and rapid pulse without strength.
Therapeutic Method: three groups of each 30 examples, accept respectively embodiment 1, embodiment 2, embodiment 3 umbilicus patch clinical treatments, external (stance) is affixed on umbilical part and changes once for 48 hours, and manifold card is taken a day off for six days.Pasting medicine phase edible maror not.
Efficacy evaluation: recovery from illness: stool is normal, or return to the front level of disease, other symptom all disappears.Effective: constipation obviously improves, interval time and just matter approach normal, or slightly dry and infrequent defecation time of stool in 72 hours, other symptom is most of to disappear.Effective: infrequent defecation time shorten 1 day, or the just dry and hard improvement of matter, other symptom all take a favorable turn.Do not heal: clinical symptoms is not improved.
After three groups of case treatments, curative effect comparative statistics result is as follows:
Group |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
Number of cases |
30 |
30 |
30 |
Recovery from illness (n%) |
12(40%) |
9(30%) |
10(33.3%) |
Effective (n%) |
10(33.3%) |
10(33.4%) |
9(30%) |
Effectively (n%) |
5(16.7%) |
7(23.3%) |
6(20%) |
Do not heal (n%) |
3(10%) |
4(13.3%) |
5(16.7%) |
Anaphylaxis (n%) |
0(0%) |
0(0%) |
0(0%) |
Total effective rate (n%) |
90% |
86.7% |
83.3% |
The specific embodiment
The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; according to the present invention, content, to nonessential improvement and adjustment more of the present invention, still belongs to protection scope of the present invention to those skilled in the art.
Embodiment 1: get 150 grams of Semen Prunis, 120 grams of Radix Adenophorae (Radix Glehniae), 150 grams of the Rhizoma Atractylodis Macrocephalaes, 120 grams of the Radix Paeoniae Albas, 150 grams of Radix et Rhizoma Rhei (processed with wine), 100 grams of Fructus Anisi Stellatis, 60 grams of Cortex Cinnamomis, 150 grams of Radix Angelicae Sinensis, after drying, mix at 35 ℃, grinding and processing becomes medicated powder more than 100 orders.
First 500 grams of vaseline are melted at 50 ℃, add 500 grams of Cera Flavas, heat to 63 ℃ completely fusing after, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted to ring size 2cm in 6cm * 7cm() the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, 1.5 grams of doses.8cm * 12cm compound membrane bag for the finished product processing is packed, and one pastes one bag.
Embodiment 2: get 120 grams of Semen Prunis, 100 grams of Radix Adenophorae (Radix Glehniae), 120 grams of the Rhizoma Atractylodis Macrocephalaes, 100 grams of the Radix Paeoniae Albas, 120 grams of Radix et Rhizoma Rhei (processed with wine), 80 grams of Fructus Anisi Stellatis, 40 grams of Cortex Cinnamomis, 120 grams of Radix Angelicae Sinensis, after drying, mix at 67 ℃, grinding and processing becomes medicated powder more than 100 orders.
First 400 grams of vaseline are melted at 60 ℃, add 400 grams of Cera Flavas, heat to 65 ℃ completely fusing after, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted to 7cm * 8cm(internal ring and is of a size of 2.5cm) the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, dose is 3 grams.8cm * 12cm compound membrane bag for the finished product processing is packed, and one pastes one bag.
Embodiment 3: get 180 grams of Semen Prunis, 140 grams of Radix Adenophorae (Radix Glehniae), 180 grams of the Rhizoma Atractylodis Macrocephalaes, 140 grams of the Radix Paeoniae Albas, 180 grams of Radix et Rhizoma Rhei (processed with wine), 120 grams of Fructus Anisi Stellatis, 80 grams of Cortex Cinnamomis, 180 grams of Radix Angelicae Sinensis, after drying, mix at 50 ℃, grinding and processing becomes medicated powder more than 100 orders.
First 600 grams of vaseline are melted at 38 ℃, add 600 grams of Cera Flavas, heat to 62 ℃ completely fusing after, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted to 7cm * 8cm(internal ring and is of a size of 2.5cm) the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, dose is 3.1 grams.8cm * 12cm compound membrane bag for the finished product processing is packed, and one pastes one bag.