CN105288413A - Medicine for treating infantile enuresis and preparation method thereof - Google Patents
Medicine for treating infantile enuresis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating infantile enuresis and a preparation method thereof. The preparation method comprises the following steps: carrying out steam sterilization on radix pseudostellariae, radix glehniae, fructus psoraleae, saline rhizoma alismatis, angelica, bran-fried Chinese yam, schisandra, soil-fried bighead atractylodes rhizome, bupleurum, dried orange peel, cassia, bitter cardamon, cherokee rose and roasted licorice in corresponding parts by weight respectively, baking, mixing, and crushing into medicinal powder of more than 100 meshes, thereby obtaining the medicine. The medicine disclosed by the invention adopts a brand-new traditional Chinese medicine formula and has the advantages of scientific compatibility of medicines, simple process, exact curative effect, no side effect and the like.
Description
Technical field
The invention belongs to application in TCM technical field, relate to a kind of medicine for the treatment of bed-wetting, particularly relate to a kind of medicine for the treatment of child and wetting the bed.
Background technology
The enuresis, also known as bed-wetting, is that children's sleeps middle incontinence of urine, a kind of disease that rear of waking up is felt.Betide the child of more than 5 years old, not automatic micturition in sleep, be multiplely born in night.The lighter's number night 1 time, severe one one night repeatedly.
The traditional Chinese medical science thinks bed-wetting, and multifactor body is weak, and kidney qi is not filled, lower first deficiency and coldness, and functioning of bladder functional disorder, can not restrict water channel; Or deficiency of both the splenic and pulmonary QI, deficiency of the upper portion of the body resulting in inability to control the lower portion; Or dampness-heat of the liver, pent up bladder, gasify the not normal and enuresis.
Summary of the invention
The invention discloses a kind of medicine and preparation method thereof for the treatment of child and wetting the bed, this medicine adopts brand-new Chinese medicine formula, has that compatibility science, technique are simple, determined curative effect, the advantage such as have no side effect.
The present invention is achieved through the following technical solutions:
Treating the medicine that child wets the bed, is the medicament be made up of the raw material of following weight portion:
Radix Pseudostellariae 150-450 part Radix Glehniae 100-140 part Fructus Psoraleae 100-140 part
Rhizoma Alismatis(processed with sait) 120-180 part Radix Angelicae Sinensis 100-140 part Rhizoma Dioscoreae (parched with bran) 150-450 part
Fructus Schisandrae Chinensis 100-140 part Rhizoma Atractylodis Macrocephalae (parched with earth) 120-180 part Radix Bupleuri 30-90 part
Pericarpium Citri Reticulatae 30-90 part Cortex Cinnamomi 30-90 part Fructus Alpiniae Oxyphyllae 120-180 part
Fructus Rosae Laevigatae 100-140 part Radix Glycyrrhizae Preparata 60-140 part.
As a kind of preferred implementation, the medicine that described treatment child wets the bed is the medicament be made up of the raw material of following weight portion:
Radix Pseudostellariae 200-400 part Radix Glehniae 110-130 part Fructus Psoraleae 110-130 part
Rhizoma Alismatis(processed with sait) 135-165 part Radix Angelicae Sinensis 110-130 part Rhizoma Dioscoreae (parched with bran) 200-400 part
Fructus Schisandrae Chinensis 110-130 part Rhizoma Atractylodis Macrocephalae (parched with earth) 135-165 part Radix Bupleuri 50-70 part
Pericarpium Citri Reticulatae 50-70 part Cortex Cinnamomi 50-70 part Fructus Alpiniae Oxyphyllae 135-165 part
Fructus Rosae Laevigatae 110-130 part Radix Glycyrrhizae Preparata 80-120 part.
As a kind of preferred implementation, the medicine that described treatment child wets the bed is the medicament be made up of the raw material of following weight portion:
Radix Pseudostellariae 300 portions of Radix Glehniaes 120 parts of Fructus Psoraleaes 120 parts
Rhizoma Alismatis(processed with sait) 150 parts of Radix Angelicae Sinensis 120 parts of Rhizoma Dioscoreae (parched with bran) 300 parts
Fructus Schisandrae Chinensis 120 parts of Rhizoma Atractylodis Macrocephalae (parched with earth) 150 parts of Radix Bupleuri 60 parts
Pericarpium Citri Reticulatae 60 portions of Cortex Cinnamomis 60 parts of Fructus Alpiniae Oxyphyllae 150 parts
Fructus Rosae Laevigatae 120 parts of Radix Glycyrrhizae Preparatas 100 parts.
Certainly, according to different demand, the active component of medicine of the present invention can add various common adjuvant required when preparing different dosage form, as disintegrating agent, lubricant, binding agent etc., be prepared into said dosage form on any one pharmaceutics with the method for Chinese medicinal of routine, as described in medicament can be pill, tablet, powder, capsule etc.
Be not destroyed to both protect the medicine property of medicine; also digestive organs and respiratory tract etc. is protected; described medicament is capsule; its preparation method: be by the Radix Pseudostellariae of corresponding weight portion, Radix Glehniae, Fructus Psoraleae, Rhizoma Alismatis(processed with sait), Radix Angelicae Sinensis, Rhizoma Dioscoreae (parched with bran), Fructus Schisandrae Chinensis, Rhizoma Atractylodis Macrocephalae (parched with earth), Radix Bupleuri, Pericarpium Citri Reticulatae, Cortex Cinnamomi, Fructus Alpiniae Oxyphyllae, Fructus Rosae Laevigatae, Radix Glycyrrhizae Preparata through steam sterilization respectively, oven dry, mix, be ground into the medicated powder of more than 100 orders, incapsulate and get final product.Preferably, can dry at 35-50 DEG C.
Certainly, conventional medicament processing method is adopted can also to be processed into other dosage forms.
In the present invention, the pharmacology analysis of each Chinese medicine is as follows:
Radix Pseudostellariae, sweet in the mouth, micro-hardship, tepor, enters lung, spleen channel, mends strengthening spleen and lung, supplementing QI for promoting the production of body fluid, for weakness of the spleen and stomach, inappetence, lassitude, impairment of both QI and YIN, dry cough expectorant is few, spontaneous perspiration is breathed hard, and the convalescent stage of febrile disease deficiency of vital energy Tianjin wound, and interior-heat is thirsty, or neurasthenia, palpitation and insomnia, dizzy forgetful;
Radix Glehniae, sweet-bitter flavor is light, cool, cold nature, sweet in the mouth, and micro-hardship, enters lung, spleen channel, nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid, again can nourishing the liver, for lung-heat type cough, chronic cough expectorant blood, calentura Tianjin wound is thirsty;
Fructus Psoraleae, bitter in the mouth, pungent, warm in nature, return kidney, spleen channel, kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, lumbago due to renal deficiency, frequent micturition, bed-wetting, kidney leaks, warming spleen and stopping diarrha, helping inspiration to relieve asthma;
Rhizoma Alismatis(processed with sait) is sweet in the mouth, light, cold in nature.Return kidney, urinary bladder channel, promoting diuresis to eliminate damp pathogen, expel the heat-evil, change turbid blood fat reducing; For dysuria, edema distension, oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria, hyperlipemia;
Radix Angelicae Sinensis, sweet in the mouth, pungent, warm, return liver, the heart, spleen channel, enrich blood and invigorate blood circulation, moisturize laxation, all cards of main blood deficiency; For blood deficiency dull yellowish colored skin, dizzy cardiopalmus, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, heavy after bloody dysentery, ulcer sores, injury from falling down;
Rhizoma Dioscoreae (parched with bran), sweet in the mouth, property is put down, and enters lung, spleen, kidney channel, supplementing QI and nourishing YIN, spleen reinforcing lung kidney, treating spontaneous emission and leukorrhagia; For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst;
Fructus Schisandrae Chinensis, sour in the mouth, sweet, warm in nature, return lung, the heart, kidney channel, restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia;
Rhizoma Atractylodis Macrocephalae (parched with earth), bitter in the mouth, sweet, warm in nature, return spleen, stomach warp, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis; For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration;
Radix Bupleuri, acrid in the mouth, hardship, cold nature, returns liver, gallbladder, lung meridian, reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, preventing the attack (or recurrence) of malaria of bringing down a fever; For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium;
Pericarpium Citri Reticulatae, bitter in the mouth, pungent, warm in nature, return lung, spleen channel, regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm; For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm;
Cortex Cinnamomi, acrid in the mouth, sweet, extremely hot in nature, returns kidney, spleen, the heart, Liver Channel, has that to mend fire supporing yang, guiding fire to origin, dispersing cold for relieving pain, effect of promoting the flow of QI-blood by warming the meridian; For sexual impotence cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, upward floating of YANG in deficiency condition, dizzy conjunctival congestion, trusted subordinate's cold type of pain, and deficiency and coldness is vomited and diarrhoea, and colic of cold type is suffered from abdominal pain;
Fructus Alpiniae Oxyphyllae, acrid in the mouth, warm in nature, enter spleen, kidney channel, warming the spleen, warming the kidney, solid and gas, arresting seminal emission; Cure mainly cold air stomachache, invasion by pathogenic cold vomit and diarrhoea, many salivas, seminal emission, dribbling urination, night many urine;
Fructus Rosae Laevigatae, sour in the mouth, sweet, puckery, property is put down, and returns kidney, bladder, large intestine channel, controlling nocturnal emission with astringent drugs reducing urination, stopping metrorrhagia and leukorrhagia, relieving diarrhea with astringents; For emission and spermatorrhea, enuresis frequent micturition, bleeding not during menses, chronic diarrhea chronic dysentery;
Radix Glycyrrhizae Preparata, sweet in the mouth, property is put down, and enters spleen, stomach warp, invigorating the spleen and replenishing QI, and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription.
In the present invention, all medicine compatibilities, have kidney and spleen invigorating, warming and recuperating the kidney-YANG, and the effect that QI invigorating is astringent or styptic treatment for spontaneous sweating has good therapeutic effect to infantile enuresis.Wherein, Radix Glehniae and Radix Pseudostellariae, Radix Angelicae Sinensis, Rhizoma Dioscoreae (parched with bran), Fructus Alpiniae Oxyphyllae, Radix Glycyrrhizae Preparata compatibility, can strengthen the body constitution of bed-wetting child, nurses one's health spleen lung kidney, make enuresis frequent micturition symptom be improved significantly; Fructus Psoraleae and Rhizoma Atractylodis Macrocephalae (parched with earth) synergism, better to the kidney warming effect; Rhizoma Alismatis(processed with sait) and Rhizoma Atractylodis Macrocephalae (parched with earth), Pericarpium Citri Reticulatae, Rhizoma Dioscoreae (parched with bran) combined effect, can better to kidney, bladder two through nursing one's health, child is wet the bed and can fundamentally be treated; Fructus Schisandrae Chinensis and Cortex Cinnamomi, Radix Pseudostellariae, northern husky synergism, at performance conditioning health, while regulating the effect of kidney channel, strengthening is urinated neural reaction; Radix Bupleuri and Pericarpium Citri Reticulatae, Radix Angelicae Sinensis, Cortex Cinnamomi, Radix Pseudostellariae, Radix Glehniae, Radix Glycyrrhizae Preparata compatibility, QI invigorating in can adjusting better, can to sleep the middle enuresis to children's better, subjective symptoms is not treated; Fructus Rosae Laevigatae and Fructus Schisandrae Chinensis, Rhizoma Dioscoreae (parched with bran) combined effect, spleen reinforcing kidney, to nocturia, frequent micturition, sleep after the enuresis have good therapeutic effect.
Detailed description of the invention
Embodiment 1
A kind of medicine for the treatment of child and wetting the bed, by Radix Pseudostellariae 450g, Radix Glehniae 140g, Fructus Psoraleae 140g, Rhizoma Alismatis(processed with sait) 180g, Radix Angelicae Sinensis 140g, Rhizoma Dioscoreae (parched with bran) 450g, Fructus Schisandrae Chinensis 140g, Rhizoma Atractylodis Macrocephalae (parched with earth) 120g, Radix Bupleuri 30g, Pericarpium Citri Reticulatae 30g, Cortex Cinnamomi 30g, Fructus Alpiniae Oxyphyllae 120g, Fructus Rosae Laevigatae 100g, Radix Glycyrrhizae Preparata 60g respectively through steam sterilization, dry at 35 DEG C, mix, be ground into 250 object medicated powder, incapsulate and get final product.
Embodiment 2
A kind of medicine for the treatment of child and wetting the bed, by Radix Pseudostellariae 150g, Radix Glehniae 100g, Fructus Psoraleae 100g, Rhizoma Alismatis(processed with sait) 120g, Radix Angelicae Sinensis 100g, Rhizoma Dioscoreae (parched with bran) 150g, Fructus Schisandrae Chinensis 100g, Rhizoma Atractylodis Macrocephalae (parched with earth) 180g, Radix Bupleuri 90g, Pericarpium Citri Reticulatae 90g, Cortex Cinnamomi 90g, Fructus Alpiniae Oxyphyllae 180g, Fructus Rosae Laevigatae 140g, Radix Glycyrrhizae Preparata 140g respectively through steam sterilization, dry at 50 DEG C, mix, be ground into 150 object medicated powder, incapsulate and get final product.
Embodiment 3
A kind of medicine for the treatment of child and wetting the bed, by Radix Pseudostellariae 400g, Radix Glehniae 110g, Fructus Psoraleae 130g, Rhizoma Alismatis(processed with sait) 135g, Radix Angelicae Sinensis 130g, Rhizoma Dioscoreae (parched with bran) 200g, Fructus Schisandrae Chinensis 130g, Rhizoma Atractylodis Macrocephalae (parched with earth) 135g, Radix Bupleuri 70g, Pericarpium Citri Reticulatae 70g, Cortex Cinnamomi 70g, Fructus Alpiniae Oxyphyllae 165g, Fructus Rosae Laevigatae 130g, Radix Glycyrrhizae Preparata 120g respectively through steam sterilization, dry at 45 DEG C, mix, be ground into 100 object medicated powder, incapsulate and get final product.
Embodiment 4
A kind of medicine for the treatment of child and wetting the bed, by Radix Pseudostellariae 200g, Radix Glehniae 130g, Fructus Psoraleae 110g, Rhizoma Alismatis(processed with sait) 165g, Radix Angelicae Sinensis 110g, Rhizoma Dioscoreae (parched with bran) 400g, Fructus Schisandrae Chinensis 110g, Rhizoma Atractylodis Macrocephalae (parched with earth) 165g, Radix Bupleuri 50g, Pericarpium Citri Reticulatae 50g, Cortex Cinnamomi 50g, Fructus Alpiniae Oxyphyllae 135g, Fructus Rosae Laevigatae 110g, Radix Glycyrrhizae Preparata 80g respectively through steam sterilization, dry at 12 DEG C, mix, be ground into 200 object medicated powder, incapsulate and get final product.
Embodiment 5
A kind of medicine for the treatment of child and wetting the bed, by Radix Pseudostellariae 300g, Radix Glehniae 120g, Fructus Psoraleae 120g, Rhizoma Alismatis(processed with sait) 150g, Radix Angelicae Sinensis 120g, Rhizoma Dioscoreae (parched with bran) 300g, Fructus Schisandrae Chinensis 120g, Rhizoma Atractylodis Macrocephalae (parched with earth) 150g, Radix Bupleuri 60g, Pericarpium Citri Reticulatae 60g, Cortex Cinnamomi 60g, Fructus Alpiniae Oxyphyllae 150g, Fructus Rosae Laevigatae 120g, Radix Glycyrrhizae Preparata 100g respectively through steam sterilization, dry at 38 DEG C, mix, be ground into 300 object medicated powder, incapsulate and get final product.
In order to investigate the clinical efficacy of medicine of the present invention further, the present invention also will carry out following clinical trial.
1. case-data
Observe 350 routine patients, be outpatient service and the admissions office patient of certain academy of traditional Chinese medicine, patient reaches and should control urinate the age (>=5 years old), and it is comparatively dark to there is sleep, not easily wakes up, wets the bed every night or every several days, very then a nocturia bed for several times, and urine is conventional and urinate phenomenons such as cultivating discovery how without exception.300 routine patient's single-blind randomizeds are divided into 6 groups, and 1-5 group is treatment group, and 6-7 group is matched group, and often organize each 50 examples, above-mentioned seven groups are compared at sex, age, the course of disease, coincident with severity degree of condition and accompanying diseases etc., and no significant difference (P >=0.05), has comparability.
2. Therapeutic Method.
The medicine that 2.1 treatment groups take the treatment child bed-wetting that embodiment of the present invention 1-5 obtains to the patient in 1-5 group respectively carries out clinical treatment; Usage and dosage: oral, 3-4 tablet/time, 2-3 times/day; Period in a medicine avoids pungent irritating food.
2.2 matched groups give the conventional western medicine such as imipramine, ephedrine, Desmopressin, amitriptyline, Desmopressin and oxibutynin according to the different situations of the patient in 6 groups, take medicine, or suitably adjust by the description of medicine; Medicine that the obtained treatment child of embodiment 3 wets the bed is given and conventional western medicine carries out Comprehensive Treatment according to the different situations of the patient in 7 groups.
3. observation index.
3.1 curative effect index patient subjective symptomss, record respectively to the symptom before and after patient treatment, pass judgment on therapeutic effect according to criterion of cure, effectively standard.
The general health check-up project of 3.2 safety indexes (body temperature, breathing, pulse, blood pressure), hematuria stool routine, darling renal function inspection etc., to begin a project all before medication and terminate rear each inspection each course for the treatment of once, observe untoward reaction at any time.
4. criterion of therapeutical effect and therapeutic outcome.
4.1 diagnostic criterias: with reference to the regulation of the diagnosis basis of enuresis, syndrome-classification, efficacy evaluation in " People's Republic of China's traditional Chinese medicine industry standard-TCM Pediatrics disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine promulgates, determine following standard:
Cure: through treating without enuresis phenomenon in one month, without recurrence in half a year;
Take a turn for the better: after treatment, enuresis number of times reduces, and can wake and urinate in sleep, occasionally have enuresis phenomenon;
Invalid: after treatment, clinical symptoms is without improvement.
4.2 7 groups of patient's comparitive study, in table 1.
Table 1 seven groups of patient's comparitive study
。
4.3 safety indexes are observed
Before and after this clinical observation treatment, seven groups of general health check-up projects of patient, the inspection of hematuria stool routine, cardiac inspections etc. have no significant change.Viewing duration, seven groups there is not serious adverse events during this clinical observation, and before and after treatment, hepatic and renal function and routine blood test index of correlation are all without significant difference.
As can be seen from the clinical therapeutic efficacy of 1-5 group, the present invention can reach so good therapeutic effect, there is significant relationship with reasonable compatibility of the present invention, arbitrarily change the amount of each component in the zone of reasonableness of each Chinese crude drug setting in the present invention, to therapeutic effect no significant difference.
Visible, simple Chinese medicine of the present invention and the Western medicine of relying on coordinates Chinese medicine of the present invention, and more can significantly improve the curative effect of child's bed-wetting than simple doctor trained in Western medicine Primary Care, and there is not side effect, patient compliance is good, has actual clinical meaning.
Claims (8)
1. treat the medicine that child wets the bed, it is characterized in that the medicament be made up of the raw material of following weight portion:
Radix Pseudostellariae 150-450 part Radix Glehniae 100-140 part Fructus Psoraleae 100-140 part
Rhizoma Alismatis(processed with sait) 120-180 part Radix Angelicae Sinensis 100-140 part Rhizoma Dioscoreae (parched with bran) 150-450 part
Fructus Schisandrae Chinensis 100-140 part Rhizoma Atractylodis Macrocephalae (parched with earth) 120-180 part Radix Bupleuri 30-90 part
Pericarpium Citri Reticulatae 30-90 part Cortex Cinnamomi 30-90 part Fructus Alpiniae Oxyphyllae 120-180 part
Fructus Rosae Laevigatae 100-140 part Radix Glycyrrhizae Preparata 60-140 part.
2. treat the medicine that child wets the bed as claimed in claim 1, it is characterized in that the medicament be made up of the raw material of following weight portion:
Radix Pseudostellariae 200-400 part Radix Glehniae 110-130 part Fructus Psoraleae 110-130 part
Rhizoma Alismatis(processed with sait) 135-165 part Radix Angelicae Sinensis 110-130 part Rhizoma Dioscoreae (parched with bran) 200-400 part
Fructus Schisandrae Chinensis 110-130 part Rhizoma Atractylodis Macrocephalae (parched with earth) 135-165 part Radix Bupleuri 50-70 part
Pericarpium Citri Reticulatae 50-70 part Cortex Cinnamomi 50-70 part Fructus Alpiniae Oxyphyllae 135-165 part
Fructus Rosae Laevigatae 110-130 part Radix Glycyrrhizae Preparata 80-120 part.
3. treat the medicine that child wets the bed as claimed in claim 1, it is characterized in that the medicament be made up of the raw material of following weight portion:
Radix Pseudostellariae 300 portions of Radix Glehniaes 120 parts of Fructus Psoraleaes 120 parts
Rhizoma Alismatis(processed with sait) 150 parts of Radix Angelicae Sinensis 120 parts of Rhizoma Dioscoreae (parched with bran) 300 parts
Fructus Schisandrae Chinensis 120 parts of Rhizoma Atractylodis Macrocephalae (parched with earth) 150 parts of Radix Bupleuri 60 parts
Pericarpium Citri Reticulatae 60 portions of Cortex Cinnamomis 60 parts of Fructus Alpiniae Oxyphyllae 150 parts
Fructus Rosae Laevigatae 120 parts of Radix Glycyrrhizae Preparatas 100 parts.
4., as the medicine that treatment child as described in arbitrary in claim 1-3 wets the bed, it is characterized in that: described medicament is said dosage form on any one pharmaceutics.
5. treat the medicine that child wets the bed as claimed in claim 4, it is characterized in that: described medicament is pill, tablet, powder, capsule.
6. treat the medicine that child wets the bed as claimed in claim 5, it is characterized in that: described medicament is capsule.
7. treat child as claimed in claim 6 to wet the bed the preparation method of medicine, it is characterized in that: be by the Radix Pseudostellariae of corresponding weight portion, Radix Glehniae, Fructus Psoraleae, Rhizoma Alismatis(processed with sait), Radix Angelicae Sinensis, Rhizoma Dioscoreae (parched with bran), Fructus Schisandrae Chinensis, Rhizoma Atractylodis Macrocephalae (parched with earth), Radix Bupleuri, Pericarpium Citri Reticulatae, Cortex Cinnamomi, Fructus Alpiniae Oxyphyllae, Fructus Rosae Laevigatae, Radix Glycyrrhizae Preparata through steam sterilization respectively, oven dry, mix, be ground into the medicated powder of more than 100 orders, incapsulate and get final product.
8. treat child as claimed in claim 7 to wet the bed the preparation method of medicine, it is characterized in that: dry at 35-50 DEG C.
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| CN107233465A (en) * | 2017-07-30 | 2017-10-10 | 赵爱良 | It is a kind of to treat medicine of child bed-wetting and preparation method thereof |
| CN116688046A (en) * | 2023-07-12 | 2023-09-05 | 河南中医药大学第一附属医院 | Traditional Chinese medicine composition for treating children enuresis due to spleen-lung qi deficiency, and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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